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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7163730
log Bayes Factor = 19.767
Chromosome 15   position 78,814,681  (GRCh37) Explore rs7163730 on Ensembl!
Variant rs7163730 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.004 0.996
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.004 0.996
I73 Other peripheral vascular diseases
0.000 0.006 0.994
J90-J94 Other diseases of pleura
0.000 0.007 0.993
I70 Atherosclerosis
0.000 0.008 0.992
J92 Pleural plaque
0.000 0.011 0.989
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.014 0.986
I73.9 Peripheral vascular disease, unspecified
0.000 0.015 0.985
I60-I69 Cerebrovascular diseases
0.000 0.015 0.985
Chapter IX Diseases of the circulatory system
0.000 0.017 0.983
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.018 0.982
J42 Unspecified chronic bronchitis
0.000 0.019 0.981
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.023 0.977
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.026 0.974
J92.0 Pleural plaque with presence of asbestos
0.000 0.027 0.973
I60 Subarachnoid haemorrhage
0.000 0.032 0.968
J60-J70 Lung diseases due to external agents
0.000 0.032 0.968
J95-J99 Other diseases of the respiratory system
0.000 0.035 0.965
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.043 0.957
I67 Other cerebrovascular diseases
0.000 0.044 0.956
I69 Sequelae of cerebrovascular disease
0.000 0.051 0.949
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.054 0.946
J98 Other respiratory disorders
0.000 0.059 0.941
I27 Other pulmonary heart diseases
0.000 0.060 0.940
I26 Pulmonary embolism
0.000 0.061 0.939
J92.9 Pleural plaque without asbestos
0.000 0.062 0.938
J98.1 Pulmonary collapse
0.000 0.069 0.931
I77 Other disorders of arteries and arterioles
0.000 0.071 0.929
I27.9 Pulmonary heart disease, unspecified
0.000 0.076 0.924
J90 Pleural effusion, not elsewhere classified
0.000 0.088 0.912
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.093 0.907
I67.9 Cerebrovascular disease, unspecified
0.000 0.094 0.906
I73.0 Raynaud's syndrome
0.000 0.104 0.896
I69.3 Sequelae of cerebral infarction
0.000 0.109 0.891
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.109 0.891
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.116 0.884
I72 Other aneurysm
0.000 0.126 0.874
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.135 0.865
J86 Pyothorax
0.000 0.145 0.855
I60.8 Other subarachnoid haemorrhage
0.000 0.150 0.850
I67.8 Other specified cerebrovascular diseases
0.000 0.157 0.843
I77.1 Stricture of artery
0.000 0.163 0.837
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.163 0.837
J43.2 Centrilobular emphysema
0.000 0.167 0.833
I67.1 Cerebral aneurysm, nonruptured
0.000 0.171 0.829
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.171 0.829
J98.4 Other disorders of lung
0.000 0.175 0.825
J93 Pneumothorax
0.000 0.175 0.825
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.176 0.824
J86.9 Pyothorax without fistula
0.000 0.178 0.822
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.179 0.821
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.180 0.820
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.190 0.810
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.194 0.806
I77.0 Arteriovenous fistula, acquired
0.000 0.199 0.801
I72.0 Aneurysm of carotid artery
0.000 0.203 0.797
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.212 0.788
I71.0 Dissection of aorta [any part]
0.000 0.214 0.786
I70.0 Atherosclerosis of aorta
0.000 0.233 0.767
J60 Coalworker's pneumoconiosis
0.000 0.234 0.766
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.234 0.766
J98.9 Respiratory disorder, unspecified
0.000 0.238 0.762
J93.1 Other spontaneous pneumothorax
0.000 0.240 0.760
I61 Intracerebral haemorrhage
0.000 0.245 0.755
J64 Unspecified pneumoconiosis
0.000 0.251 0.749
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.252 0.748
I72.8 Aneurysm of other specified arteries
0.000 0.270 0.730
I77.2 Rupture of artery
0.000 0.273 0.727
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.278 0.722
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.287 0.713
I28 Other diseases of pulmonary vessels
0.000 0.288 0.712
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I78 Diseases of capillaries
0.000 0.293 0.707
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.293 0.706
I00-I02 Acute rheumatic fever
0.000 0.298 0.702
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.299 0.701
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.303 0.697
J69 Pneumonitis due to solids and liquids
0.000 0.305 0.695
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.306 0.694
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.306 0.694
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.306 0.694
J66 Airway disease due to specific organic dust
0.000 0.306 0.694
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.306 0.694
J62 Pneumoconiosis due to dust containing silica
0.000 0.306 0.694
J65 Pneumoconiosis associated with tuberculosis
0.000 0.306 0.694
I27.8 Other specified pulmonary heart diseases
0.000 0.307 0.693
J96 Respiratory failure, not elsewhere classified
0.000 0.308 0.692
J98.2 Interstitial emphysema
0.000 0.312 0.688
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.314 0.686
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.314 0.686
I67.5 Moyamoya disease
0.000 0.314 0.686
I67.4 Hypertensive encephalopathy
0.000 0.314 0.686
I67.3 Progressive vascular leukoencephalopathy
0.000 0.314 0.686
J98.3 Compensatory emphysema
0.000 0.325 0.675
I27.1 Kyphoscoliotic heart disease
0.000 0.326 0.674
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.328 0.672
I72.9 Aneurysm of unspecified site
0.000 0.329 0.671
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.331 0.669
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.331 0.669
I77.5 Necrosis of artery
0.000 0.334 0.666
I77.4 Coeliac artery compression syndrome
0.000 0.334 0.666
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.334 0.666
I74 Arterial embolism and thrombosis
0.000 0.344 0.656
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.350 0.650
I27.0 Primary pulmonary hypertension
0.000 0.354 0.646
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.356 0.644
J70 Respiratory conditions due to other external agents
0.000 0.360 0.640
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.373 0.627
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.373 0.627
I72.1 Aneurysm of artery of upper extremity
0.000 0.373 0.627
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.375 0.625
I73.8 Other specified peripheral vascular diseases
0.000 0.375 0.625
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.378 0.621
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.379 0.621
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.383 0.617
J93.0 Spontaneous tension pneumothorax
0.000 0.387 0.613
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.394 0.606
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.396 0.604
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.399 0.601
I70.1 Atherosclerosis of renal artery
0.000 0.407 0.593
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.409 0.591
I79.1 Aortitis in diseases classified elsewhere
0.000 0.409 0.591
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.409 0.591
J85 Abscess of lung and mediastinum
0.000 0.411 0.589
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.412 0.588
J86.0 Pyothorax with fistula
0.000 0.417 0.583
J43.8 Other emphysema
0.000 0.423 0.577
J99.0 Rheumatoid lung disease
0.000 0.424 0.576
I72.3 Aneurysm of iliac artery
0.000 0.434 0.566
J98.6 Disorders of diaphragm
0.000 0.434 0.565
J40 Bronchitis, not specified as acute or chronic
0.000 0.435 0.565
I77.8 Other specified disorders of arteries and arterioles
0.000 0.440 0.559
J94 Other pleural conditions
0.000 0.442 0.557
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.450 0.550
I77.3 Arterial fibromuscular dysplasia
0.000 0.451 0.548
I67.2 Cerebral atherosclerosis
0.000 0.457 0.543
J93.8 Other pneumothorax
0.000 0.461 0.539
J09-J18 Influenza and pneumonia
0.000 0.462 0.538
J69.8 Pneumonitis due to other solids and liquids
0.000 0.462 0.538
I72.2 Aneurysm of renal artery
0.000 0.464 0.535
I27.2 Other secondary pulmonary hypertension
0.000 0.469 0.531
I72.4 Aneurysm of artery of lower extremity
0.000 0.475 0.525
J95.8 Other postprocedural respiratory disorders
0.000 0.475 0.525
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.476 0.524
I28.8 Other specified diseases of pulmonary vessels
0.000 0.478 0.521
I77.6 Arteritis, unspecified
0.000 0.479 0.521
I62 Other nontraumatic intracranial haemorrhage
0.000 0.481 0.519
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.482 0.517
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.487 0.513
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.490 0.510
I28.1 Aneurysm of pulmonary artery
0.000 0.490 0.510
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.490 0.510
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I78.9 Disease of capillaries, unspecified
0.000 0.493 0.507
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.493 0.506
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.493 0.506
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.493 0.506
I68.0 Cerebral amyloid angiopathy
0.000 0.493 0.506
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.494 0.506
I05-I09 Chronic rheumatic heart diseases
0.000 0.494 0.506
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.496 0.504
J46 Status asthmaticus
0.000 0.497 0.503
I02 Rheumatic chorea
0.000 0.497 0.503
I01 Rheumatic fever with heart involvement
0.000 0.497 0.503
I00 Rheumatic fever without mention of heart involvement
0.000 0.500 0.500
J69.1 Pneumonitis due to oils and essences
0.000 0.501 0.498
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.502 0.498
J62.0 Pneumoconiosis due to talc dust
0.000 0.502 0.498
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.502 0.498
J63.5 Stannosis
0.000 0.502 0.498
J63.4 Siderosis
0.000 0.502 0.498
J63.3 Graphite fibrosis (of lung)
0.000 0.502 0.498
J63.2 Berylliosis
0.000 0.502 0.498
J63.1 Bauxite fibrosis (of lung)
0.000 0.502 0.498
J63.0 Aluminosis (of lung)
0.000 0.502 0.498
J66.8 Airway disease due to other specific organic dusts
0.000 0.502 0.498
J66.2 Cannabinosis
0.000 0.502 0.498
J66.1 Flax-dresser's disease
0.000 0.502 0.498
J66.0 Byssinosis
0.000 0.502 0.498
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.502 0.498
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J96.9 Respiratory failure, unspecified
0.000 0.504 0.496
J96.1 Chronic respiratory failure
0.000 0.504 0.496
J96.0 Acute respiratory failure
0.000 0.504 0.496
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.504 0.496
I78.8 Other diseases of capillaries
0.000 0.513 0.487
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.517 0.483
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.519 0.481
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.522 0.477
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.522 0.477
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.522 0.477
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.522 0.477
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.524 0.476
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.528 0.472
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.529 0.471
J91 Pleural effusion in conditions classified elsewhere
0.000 0.530 0.470
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.530 0.470
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.537 0.463
I74.8 Embolism and thrombosis of other arteries
0.000 0.537 0.463
J95.5 Postprocedural subglottic stenosis
0.000 0.538 0.462
J95.4 Mendelson's syndrome
0.000 0.538 0.462
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.538 0.462
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.538 0.462
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.538 0.462
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.539 0.461
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.541 0.459
J70.8 Respiratory conditions due to other specified external agents
0.000 0.541 0.459
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.541 0.459
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.541 0.459
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.541 0.459
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.541 0.459
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.548 0.452
J69.0 Pneumonitis due to food and vomit
0.000 0.549 0.451
J18 Pneumonia, organism unspecified
0.000 0.551 0.449
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.554 0.445
J67.7 Air-conditioner and humidifier lung
0.000 0.554 0.445
J67.6 Maple-bark-stripper's lung
0.000 0.554 0.445
J67.5 Mushroom-worker's lung
0.000 0.554 0.445
J67.4 Maltworker's lung
0.000 0.554 0.445
J67.3 Suberosis
0.000 0.554 0.445
J67.1 Bagassosis
0.000 0.554 0.445
J67.0 Farmer's lung
0.000 0.554 0.445
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.559 0.441
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.560 0.440
I74.5 Embolism and thrombosis of iliac artery
0.000 0.564 0.436
J18.1 Lobar pneumonia, unspecified
0.000 0.565 0.435
J98.8 Other specified respiratory disorders
0.000 0.566 0.434
J93.9 Pneumothorax, unspecified
0.000 0.568 0.432
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.572 0.427
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.574 0.425
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.575 0.425
J85.1 Abscess of lung with pneumonia
0.000 0.576 0.424
J85.3 Abscess of mediastinum
0.000 0.577 0.422
J85.0 Gangrene and necrosis of lung
0.000 0.577 0.422
J10 Influenza due to identified influenza virus
0.000 0.578 0.422
I61.8 Other intracerebral haemorrhage
0.000 0.585 0.415
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.587 0.413
J67.2 Bird fancier's lung
0.000 0.588 0.411
I09 Other rheumatic heart diseases
0.000 0.594 0.406
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.595 0.404
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.596 0.404
J94.9 Pleural condition, unspecified
0.000 0.600 0.400
J94.0 Chylous effusion
0.000 0.600 0.400
J94.8 Other specified pleural conditions
0.000 0.600 0.400
J20-J22 Other acute lower respiratory infections
0.000 0.600 0.400
J94.1 Fibrothorax
0.000 0.601 0.399
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.605 0.395
J95.0 Tracheostomy malfunction
0.000 0.613 0.387
I07 Rheumatic tricuspid valve diseases
0.000 0.613 0.387
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.614 0.386
J09 Influenza due to certain identified influenza virus
0.000 0.614 0.386
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.621 0.379
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.622 0.378
J17 Pneumonia in diseases classified elsewhere
0.000 0.634 0.366
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.639 0.361
I01.8 Other acute rheumatic heart disease
0.000 0.639 0.361
I01.2 Acute rheumatic myocarditis
0.000 0.639 0.361
I01.1 Acute rheumatic endocarditis
0.000 0.639 0.361
I01.0 Acute rheumatic pericarditis
0.000 0.639 0.361
I02.9 Rheumatic chorea without heart involvement
0.000 0.639 0.361
I02.0 Rheumatic chorea with heart involvement
0.000 0.639 0.361
J85.2 Abscess of lung without pneumonia
0.000 0.640 0.360
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.641 0.359
J96.09 Acute respiratory failure; Type unspecified
0.000 0.644 0.356
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.644 0.356
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.644 0.356
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.644 0.356
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.644 0.356
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.644 0.356
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.644 0.356
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.644 0.356
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.644 0.356
I05 Rheumatic mitral valve diseases
0.000 0.646 0.354
J12 Viral pneumonia, not elsewhere classified
0.000 0.654 0.345
I06 Rheumatic aortic valve diseases
0.000 0.665 0.335
I09.9 Rheumatic heart disease, unspecified
0.000 0.665 0.335
I78.1 Naevus, nonneoplastic
0.000 0.665 0.335
I62.1 Nontraumatic extradural haemorrhage
0.000 0.666 0.334
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.669 0.331
J14 Pneumonia due to Haemophilus influenzae
0.000 0.674 0.326
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.674 0.326
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.676 0.324
J18.2 Hypostatic pneumonia, unspecified
0.000 0.678 0.322
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.681 0.319
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.686 0.314
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.692 0.307
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.697 0.303
I07.1 Tricuspid insufficiency
0.000 0.698 0.302
I05.1 Rheumatic mitral insufficiency
0.000 0.702 0.298
J18.8 Other pneumonia, organism unspecified
0.000 0.707 0.293
I09.8 Other specified rheumatic heart diseases
0.000 0.708 0.291
I09.2 Chronic rheumatic pericarditis
0.000 0.708 0.291
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.708 0.291
I09.0 Rheumatic myocarditis
0.000 0.708 0.291
J84 Other interstitial pulmonary diseases
0.000 0.714 0.286
J21 Acute bronchiolitis
0.000 0.718 0.282
J18.9 Pneumonia, unspecified
0.000 0.721 0.279
I07.9 Tricuspid valve disease, unspecified
0.000 0.722 0.278
I07.8 Other tricuspid valve diseases
0.000 0.722 0.278
I07.2 Tricuspid stenosis with insufficiency
0.000 0.722 0.278
I07.0 Tricuspid stenosis
0.000 0.722 0.278
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.723 0.277
J16.0 Chlamydial pneumonia
0.000 0.723 0.277
J15.2 Pneumonia due to staphylococcus
0.000 0.723 0.277
J45 Asthma
0.000 0.725 0.275
J15.8 Other bacterial pneumonia
0.000 0.727 0.273
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.729 0.271
J15.5 Pneumonia due to Escherichia coli
0.000 0.730 0.270
J20 Acute bronchitis
0.000 0.732 0.267
J15.4 Pneumonia due to other streptococci
0.000 0.736 0.264
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.737 0.263
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.738 0.262
J15.3 Pneumonia due to streptococcus, group B
0.000 0.742 0.257
J00-J06 Acute upper respiratory infections
0.000 0.744 0.256
I05.8 Other mitral valve diseases
0.000 0.746 0.254
I05.0 Mitral stenosis
0.000 0.746 0.254
J15.9 Bacterial pneumonia, unspecified
0.000 0.746 0.254
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.748 0.252
J12.8 Other viral pneumonia
0.000 0.752 0.248
J12.3 Human metapneumovirus pneumonia
0.000 0.752 0.248
J12.2 Parainfluenza virus pneumonia
0.000 0.752 0.248
J12.1 Respiratory syncytial virus pneumonia
0.000 0.752 0.248
J12.0 Adenoviral pneumonia
0.000 0.752 0.248
J94.2 Haemothorax
0.001 0.754 0.246
I63 Cerebral infarction
0.000 0.759 0.241
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.759 0.240
I06.8 Other rheumatic aortic valve diseases
0.000 0.759 0.240
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.759 0.240
I06.1 Rheumatic aortic insufficiency
0.000 0.759 0.240
J11 Influenza, virus not identified
0.000 0.760 0.239
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.761 0.239
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.766 0.234
I05.2 Mitral stenosis with insufficiency
0.000 0.769 0.231
I10-I15 Hypertensive diseases
0.000 0.770 0.230
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.771 0.229
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.771 0.229
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.771 0.229
I99 Other and unspecified disorders of circulatory system
0.000 0.775 0.225
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.776 0.224
J17.3 Pneumonia in parasitic diseases
0.000 0.779 0.221
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.780 0.219
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.783 0.216
I06.0 Rheumatic aortic stenosis
0.000 0.787 0.213
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.788 0.211
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.790 0.210
J15.1 Pneumonia due to Pseudomonas
0.000 0.791 0.208
J12.9 Viral pneumonia, unspecified
0.000 0.793 0.207
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.793 0.206
J84.0 Alveolar and parietoalveolar conditions
0.000 0.794 0.205
J84.8 Other specified interstitial pulmonary diseases
0.000 0.797 0.203
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.797 0.202
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.797 0.202
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.797 0.202
J21.9 Acute bronchiolitis, unspecified
0.000 0.802 0.198
J45.8 Mixed asthma
0.000 0.802 0.197
J45.1 Nonallergic asthma
0.000 0.802 0.197
I05.9 Mitral valve disease, unspecified
0.000 0.805 0.195
J00 Acute nasopharyngitis [common cold]
0.000 0.806 0.194
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.806 0.194
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.806 0.194
I98.0 Cardiovascular syphilis
0.000 0.806 0.194
J20.7 Acute bronchitis due to echovirus
0.000 0.808 0.192
J20.6 Acute bronchitis due to rhinovirus
0.000 0.808 0.192
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.808 0.192
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.808 0.192
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.808 0.192
J20.2 Acute bronchitis due to streptococcus
0.000 0.808 0.192
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.808 0.192
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.808 0.192
J17.2 Pneumonia in mycoses
0.000 0.808 0.191
J20.8 Acute bronchitis due to other specified organisms
0.000 0.809 0.191
Z72.1 Alcohol use
0.000 0.811 0.189
Z72.0 Tobacco use
0.000 0.811 0.189
Z72 Problems related to lifestyle
0.000 0.814 0.186
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.816 0.183
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.820 0.180
I95 Hypotension
0.000 0.820 0.180
J20.9 Acute bronchitis, unspecified
0.000 0.826 0.174
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.827 0.173
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.827 0.173
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.827 0.173
J11.8 Influenza with other manifestations, virus not identified
0.001 0.828 0.172
I15 Secondary hypertension
0.000 0.830 0.170
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.831 0.169
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.831 0.169
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.833 0.167
I13 Hypertensive heart and renal disease
0.000 0.835 0.165
F17.1 Harmful use
0.000 0.836 0.164
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.839 0.160
J01 Acute sinusitis
0.000 0.841 0.159
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.842 0.157
I97.0 Postcardiotomy syndrome
0.000 0.842 0.157
I95.1 Orthostatic hypotension
0.000 0.843 0.157
I65.1 Occlusion and stenosis of basilar artery
0.001 0.843 0.156
J02 Acute pharyngitis
0.000 0.844 0.156
Z72.2 Drug use
0.000 0.851 0.149
J04 Acute laryngitis and tracheitis
0.000 0.851 0.148
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.853 0.147
I87 Other disorders of veins
0.000 0.854 0.146
J03 Acute tonsillitis
0.000 0.856 0.144
I95.8 Other hypotension
0.000 0.856 0.144
I65.2 Occlusion and stenosis of carotid artery
0.000 0.860 0.140
I81 Portal vein thrombosis
0.000 0.863 0.137
I88 Nonspecific lymphadenitis
0.000 0.864 0.136
J11.0 Influenza with pneumonia, virus not identified
0.001 0.864 0.136
I15.1 Hypertension secondary to other renal disorders
0.000 0.864 0.136
Z72.6 Gambling and betting
0.000 0.866 0.134
Z72.5 High-risk sexual behaviour
0.000 0.866 0.134
Z72.3 Lack of physical exercise
0.000 0.866 0.134
Z72.4 Inappropriate diet and eating habits
0.000 0.866 0.134
I85 Oesophageal varices
0.000 0.867 0.133
J81 Pulmonary oedema
0.000 0.867 0.133
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.867 0.133
Z72.8 Other problems related to lifestyle
0.000 0.868 0.132
J05.0 Acute obstructive laryngitis [croup]
0.000 0.868 0.132
J05.1 Acute epiglottitis
0.000 0.868 0.132
I87.1 Compression of vein
0.000 0.868 0.132
J18.0 Bronchopneumonia, unspecified
0.000 0.869 0.131
I15.9 Seconday hypertension, unspecified
0.000 0.870 0.130
I80 Phlebitis and thrombophlebitis
0.000 0.871 0.129
J47 Bronchiectasis
0.000 0.872 0.128
J45.0 Predominantly allergic asthma
0.000 0.872 0.128
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.874 0.126
I11 Hypertensive heart disease
0.000 0.874 0.125
I12 Hypertensive renal disease
0.000 0.875 0.125
I97.1 Other functional disturbances following cardiac surgery
0.000 0.877 0.123
I15.8 Other secondary hypertension
0.000 0.878 0.122
I15.2 Hypertension secondary to endocrine disorders
0.000 0.878 0.122
Z72.9 Problem related to lifestyle, unspecified
0.000 0.878 0.122
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.879 0.121
F17.2 Dependence syndrome
0.000 0.880 0.120
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.880 0.119
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.882 0.118
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.882 0.118
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.882 0.118
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.882 0.118
I85.0 Oesophageal varices with bleeding
0.000 0.883 0.117
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.883 0.117
I87.8 Other specified disorders of veins
0.000 0.883 0.117
J01.0 Acute maxillary sinusitis
0.000 0.884 0.116
J02.0 Streptococcal pharyngitis
0.000 0.884 0.116
J01.8 Other acute sinusitis
0.000 0.885 0.114
J01.4 Acute pansinusitis
0.000 0.885 0.114
J01.3 Acute sphenoidal sinusitis
0.000 0.885 0.114
J01.1 Acute frontal sinusitis
0.000 0.885 0.114
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.890 0.108
J01.2 Acute ethmoidal sinusitis
0.000 0.891 0.108
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.893 0.107
I95.0 Idiopathic hypotension
0.000 0.893 0.107
J04.2 Acute laryngotracheitis
0.000 0.893 0.106
I87.9 Disorder of vein, unspecified
0.000 0.895 0.105
I87.0 Postphlebitic syndrome
0.000 0.895 0.105
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.895 0.105
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.896 0.103
J03.0 Streptococcal tonsillitis
0.000 0.896 0.103
J04.1 Acute tracheitis
0.000 0.897 0.103
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.900 0.099
I63.8 Other cerebral infarction
0.000 0.901 0.098
I88.8 Other nonspecific lymphadenitis
0.000 0.902 0.098
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.902 0.098
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.902 0.098
J01.9 Acute sinusitis, unspecified
0.000 0.904 0.096
I15.0 Renovascular hypertension
0.000 0.904 0.096
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.907 0.092
F17.8 Other mental and behavioural disorders
0.000 0.909 0.091
F17.7 Residual and late-onset psychotic disorder
0.000 0.909 0.091
F17.6 Amnesic syndrome
0.000 0.909 0.091
F17.5 Psychotic disorder
0.000 0.909 0.091
F17.4 Withdrawal state with delirium
0.000 0.909 0.091
F17.3 Withdrawal state
0.000 0.909 0.091
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.910 0.090
F17.9 Unspecified mental and behavioural disorder
0.000 0.913 0.087

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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