TreeWAS – Variant ID: rs7178572

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.976	0.024	0.000
E11 Non-insulin-dependent diabetes mellitus	0.963	0.037	0.000
E11.3 With ophthalmic complications	0.932	0.068	0.000
E11.8 With unspecified complications	0.865	0.135	0.000
E11.6 With other specified complications	0.808	0.192	0.000
E11.5 With peripheral circulatory complications	0.799	0.201	0.000
E11.1 With ketoacidosis	0.791	0.209	0.000
E11.4 With neurological complications	0.771	0.229	0.000
E11.7 With multiple complications	0.690	0.310	0.000
E11.0 With coma	0.644	0.356	0.000
E11.2 With renal complications	0.549	0.451	0.000
Y84.6 Urinary catheterisation	0.133	0.867	0.000
E10-E14 Diabetes mellitus	0.076	0.924	0.000
E12 Malnutrition-related diabetes mellitus	0.055	0.945	0.000
E12.9 Without complications	0.039	0.960	0.000
E12.8 With unspecified complications	0.039	0.960	0.000
E12.7 With multiple complications	0.039	0.960	0.000
E12.6 With other specified complications	0.039	0.960	0.000
E12.5 With peripheral circulatory complications	0.039	0.960	0.000
E12.4 With neurological complications	0.039	0.960	0.000
E12.3 With ophthalmic complications	0.039	0.960	0.000
E12.2 With renal complications	0.039	0.960	0.000
E12.1 With ketoacidosis	0.039	0.960	0.000
E12.0 With coma	0.039	0.960	0.000
E13 Other specified diabetes mellitus	0.038	0.962	0.000
E10 Insulin-dependent diabetes mellitus	0.035	0.965	0.000
E10.2 With renal complications	0.032	0.968	0.000
E10.3 With ophthalmic complications	0.029	0.971	0.000
E13.8 With unspecified complications	0.027	0.972	0.000
E13.7 With multiple complications	0.027	0.972	0.000
E13.6 With other specified complications	0.027	0.972	0.000
E13.5 With peripheral circulatory complications	0.027	0.972	0.000
E13.4 With neurological complications	0.027	0.972	0.000
E13.2 With renal complications	0.027	0.972	0.000
E13.1 With ketoacidosis	0.027	0.972	0.000
E13.0 With coma	0.027	0.972	0.000
E13.3 With ophthalmic complications	0.027	0.973	0.000
E10.0 With coma	0.027	0.973	0.000
E10.8 With unspecified complications	0.025	0.975	0.000
E10.6 With other specified complications	0.024	0.976	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.024	0.976	0.000
E10.7 With multiple complications	0.023	0.977	0.000
E14 Unspecified diabetes mellitus	0.023	0.977	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.022	0.978	0.000
E10.5 With peripheral circulatory complications	0.021	0.979	0.000
E10.4 With neurological complications	0.020	0.980	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.020	0.980	0.000
E14.8 With unspecified complications	0.019	0.981	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.019	0.981	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.019	0.981	0.000
Y84.3 Shock therapy	0.018	0.982	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.018	0.982	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.018	0.982	0.000
Y84.1 Kidney dialysis	0.018	0.982	0.000
E14.0 With coma	0.017	0.982	0.000
E14.7 With multiple complications	0.016	0.984	0.000
E14.2 Withrenal complications	0.016	0.984	0.000
Y84.7 Blood-sampling	0.016	0.984	0.000
Y84.5 Insertion of gastric or duodenal sound	0.016	0.984	0.000
E14.1 With ketoacidosis	0.015	0.985	0.000
E14.6 With other specified complications	0.015	0.985	0.000
Y84.9 Medical procedure, unspecified	0.015	0.985	0.000
E14.5 With peripheral circulatory complications	0.015	0.985	0.000
Y84.8 Other medical procedures	0.015	0.985	0.000
E14.4 With neurological complications	0.014	0.986	0.000
Y84.4 Aspiration of fluid	0.013	0.987	0.000
E14.3 With ophthalmic complications	0.012	0.988	0.000
E13.9 Without complications	0.012	0.988	0.001
Y84.2 Radiological procedure and radiotherapy	0.011	0.989	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.011	0.989	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.011	0.989	0.000
E10.9 Without complications	0.010	0.990	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.009	0.991	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.009	0.991	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.008	0.992	0.000
I24.8 Other forms of acute ischaemic heart disease	0.008	0.992	0.000
Y84.0 Cardiac catheterisation	0.008	0.992	0.000
J84.8 Other specified interstitial pulmonary diseases	0.008	0.992	0.000
E10.1 With ketoacidosis	0.007	0.992	0.000
J84 Other interstitial pulmonary diseases	0.007	0.993	0.000
C34.1 Upper lobe, bronchus or lung	0.007	0.993	0.000
L71.9 Rosacea, unspecified	0.000	0.994	0.006
J84.1 Other interstitial pulmonary diseases with fibrosis	0.006	0.994	0.000
J84.0 Alveolar and parietoalveolar conditions	0.005	0.994	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.005	0.995	0.000
G50.0 Trigeminal neuralgia	0.005	0.995	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.995	0.005
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.995	0.005
Z11.2 Special screening examination for other bacterial diseases	0.004	0.995	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.004	0.996	0.000
I24 Other acute ischaemic heart diseases	0.004	0.996	0.000
K12.2 Cellulitis and abscess of mouth	0.000	0.996	0.004
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
G24.5 Blepharospasm	0.000	0.996	0.004
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.996	0.004
S02.20 Fracture of nasal bones (closed)	0.000	0.996	0.004
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
N83.2 Other and unspecified ovarian cysts	0.003	0.997	0.000
K41 Femoral hernia	0.000	0.997	0.003
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.997	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.003	0.997	0.000
I24.1 Dressler's syndrome	0.003	0.997	0.000
D06.9 Cervix, unspecified	0.003	0.997	0.000
C34.0 Main bronchus	0.003	0.997	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.997	0.003
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.003	0.997	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
C34 Malignant neoplasm of bronchus and lung	0.003	0.997	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.003	0.997	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.997	0.003
L02 Cutaneous abscess, furuncle and carbuncle	0.003	0.997	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.997	0.003
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.997	0.003
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.997	0.003
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
K12.0 Recurrent oral aphthae	0.000	0.997	0.003
G50 Disorders of trigeminal nerve	0.003	0.997	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.003	0.997	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.003	0.997	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.997	0.003
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.003	0.997	0.000
L71 Rosacea	0.000	0.998	0.002
E66.8 Other obesity	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.002	0.998	0.000
M65.34 Trigger finger-Hand	0.002	0.998	0.000
N83.0 Follicular cyst of ovary	0.002	0.998	0.000
K12 Stomatitis and related lesions	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
G50.8 Other disorders of trigeminal nerve	0.002	0.998	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
G50.1 Atypical facial pain	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
C34.8 Overlapping lesion of bronchus and lung	0.002	0.998	0.000
K59.3 Megacolon, not elsewhere classified	0.000	0.998	0.002
L73.8 Other specified follicular disorders	0.000	0.998	0.002
L71.8 Other rosacea	0.000	0.998	0.002
N83.6 Haematosalpinx	0.002	0.998	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
L71.0 Perioral dermatitis	0.000	0.998	0.002
E66 Obesity	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
E66.0 Obesity due to excess calories	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
Z02 Examination and encounter for administrative purposes	0.000	0.998	0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
L11.0 Acquired keratosis follicularis	0.000	0.998	0.002
N42.9 Disorder of prostate, unspecified	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.002
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.998	0.002
C62.9 Testis, unspecified	0.000	0.998	0.002
K12.1 Other forms of stomatitis	0.000	0.998	0.002
G24 Dystonia	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.002	0.998	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.002	0.998	0.000
L71.1 Rhinophyma	0.000	0.998	0.002
N83.3 Acquired atrophy of ovary and Fallopian tube	0.002	0.998	0.000
B95-B98 Bacterial, viral and other infectious agents	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
I20.0 Unstable angina	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
N83.7 Haematoma of broad ligament	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.998	0.000
E16.3 Increased secretion of glucagon	0.002	0.998	0.000
E66.1 Drug-induced obesity	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
Z02.9 Examination for administrative purposes, unspecified	0.000	0.998	0.002
Z02.7 Issue of medical certificate	0.000	0.998	0.002
Z02.6 Examination for insurance purposes	0.000	0.998	0.002
Z02.5 Examination for participation in sport	0.000	0.998	0.002
Z02.4 Examination for driving licence	0.000	0.998	0.002
Z02.3 Examination for recruitment to armed forces	0.000	0.998	0.002
Z02.2 Examination for admission to residential institution	0.000	0.998	0.002
Z02.1 Pre-employment examination	0.000	0.998	0.002
Z02.0 Examination for admission to educational institution	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.002	0.998	0.000
S79.9 Unspecified injury of hip and thigh	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.002	0.998	0.000
T18.0 Foreign body in mouth	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
G24.1 Idiopathic familial dystonia	0.000	0.998	0.002
B37.8 Candidiasis of other sites	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
G24.4 Idiopathic orofacial dystonia	0.000	0.998	0.002
G24.2 Idiopathic nonfamilial dystonia	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
E66.2 Extreme obesity with alveolar hypoventilation	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
C30.0 Nasal cavity	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
E67 Other hyperalimentation	0.001	0.998	0.000
E68 Sequelae of hyperalimentation	0.001	0.998	0.000
E16.1 Other hypoglycaemia	0.001	0.998	0.000
G24.0 Drug-induced dystonia	0.000	0.998	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
E40-E46 Malnutrition	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
D34 Benign neoplasm of thyroid gland	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.998	0.002
T18 Foreign body in alimentary tract	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
E23.6 Other disorders of pituitary gland	0.000	0.998	0.001
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.002	0.998	0.000
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.998	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.001
Q51.3 Bicornate uterus	0.001	0.998	0.000
T18.3 Foreign body in small intestine	0.001	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
G24.8 Other dystonia	0.000	0.998	0.001
G24.3 Spasmodic torticollis	0.000	0.998	0.001
Z11.8 Special screening examination for other infectious and parasitic diseases	0.001	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
D48.7 Other specified sites	0.000	0.998	0.001
Z11 Special screening examination for infectious and parasitic diseases	0.001	0.999	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.999	0.001
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.999	0.001
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.999	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.001	0.999	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.001	0.999	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.001	0.999	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.001	0.999	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.001	0.999	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.001	0.999	0.000
E67.8 Other specified hyperalimentation	0.001	0.999	0.000
E67.3 Hypervitaminosis D	0.001	0.999	0.000
E67.2 Megavitamin-B6 syndrome	0.001	0.999	0.000
E67.1 Hypercarotenaemia	0.001	0.999	0.000
E67.0 Hypervitaminosis A	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.999	0.000
T18.5 Foreign body in anus and rectum	0.001	0.999	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.999	0.001
Z99.1 Dependence on respirator	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
N83.1 Corpus luteum cyst	0.001	0.999	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.999	0.001
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.999	0.001
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.999	0.001
T18.8 Foreign body in other and multiple parts of alimentary tract	0.001	0.999	0.000
T18.4 Foreign body in colon	0.001	0.999	0.000
W10.4 Street and highway	0.000	0.999	0.001
C30 Malignant neoplasm of nasal cavity and middle ear	0.001	0.999	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.999	0.000
E45 Retarded development following protein-energy malnutrition	0.001	0.999	0.000
E43 Unspecified severe protein-energy malnutrition	0.001	0.999	0.000
E42 Marasmic kwashiorkor	0.001	0.999	0.000
E41 Nutritional marasmus	0.001	0.999	0.000
E40 Kwashiorkor	0.001	0.999	0.000
E24.2 Drug-induced Cushing's syndrome	0.001	0.999	0.000
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
Q51 Congenital malformations of uterus and cervix	0.001	0.999	0.000
H26.8 Other specified cataract	0.001	0.999	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.999	0.001
N87.0 Mild cervical dysplasia	0.001	0.999	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.999	0.001
T79.7 Traumatic subcutaneous emphysema	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.999	0.001
C48.2 Peritoneum, unspecified	0.000	0.999	0.001
C78.2 Secondary malignant neoplasm of pleura	0.001	0.999	0.000
E26.0 Primary hyperaldosteronism	0.001	0.999	0.000
I27.9 Pulmonary heart disease, unspecified	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.999	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.000	0.999	0.001
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
Z56.3 Stressful work schedule	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.001	0.999	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.999	0.001
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
C30.1 Middle ear	0.001	0.999	0.000
E44.1 Mild protein-energy malnutrition	0.001	0.999	0.000
E44.0 Moderate protein-energy malnutrition	0.001	0.999	0.000
M65.3 Trigger finger	0.001	0.999	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.999	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.999	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.999	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.999	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.999	0.000
T18.2 Foreign body in stomach	0.001	0.999	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.999	0.001
Y54.7 Agents affecting calcification	0.000	0.999	0.001
M79.58 Residual foreign body in soft tissue (Other)	0.001	0.999	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.999	0.001
F30.0 Hypomania	0.000	0.999	0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
K22.0 Achalasia of cardia	0.000	0.999	0.001
E66.9 Obesity, unspecified	0.001	0.999	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.999	0.001
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.999	0.000
V23.4 Driver injured in traffic accident	0.000	0.999	0.001
Y60.0 During surgical operation	0.001	0.999	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.001	0.999	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.001	0.999	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.999	0.001
M65.39 Trigger finger-Site unspec	0.001	0.999	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.999	0.000
N36.8 Other specified disorders of urethra	0.001	0.999	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.001	0.999	0.000
M65.38 Trigger finger-Other	0.001	0.999	0.000
M65.37 Trigger finger-Ankle/foot	0.001	0.999	0.000
M65.36 Trigger finger-Lower leg	0.001	0.999	0.000
M65.35 Trigger finger-Pelvic/thigh	0.001	0.999	0.000
M65.33 Trigger finger-Forearm	0.001	0.999	0.000
M65.32 Trigger finger-Upper arm	0.001	0.999	0.000
M65.31 Trigger finger-Shldr region	0.001	0.999	0.000
M65.30 Trigger finger-Mult sites	0.001	0.999	0.000
E24.8 Other Cushing's syndrome	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.999	0.001
E24 Cushing's syndrome	0.001	0.999	0.000
E65 Localised adiposity	0.001	0.999	0.000
T16 Foreign body in ear	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
C48.1 Specified parts of peritoneum	0.000	0.999	0.001
E26.9 Hyperaldosteronism, unspecified	0.001	0.999	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.999	0.001
W19.2 School, other institution and public administrative area	0.001	0.999	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.001	0.999	0.000
E46 Unspecified protein-energy malnutrition	0.001	0.999	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.999	0.001
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.999	0.001
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.999	0.001
Q51.2 Other doubling of uterus	0.001	0.999	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.001	0.999	0.000
T40.1 Heroin	0.001	0.999	0.000
Z43.1 Attention to gastrostomy	0.000	0.999	0.001
O86 Other puerperal infections	0.000	0.999	0.001
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.999	0.001
C48.0 Retroperitoneum	0.000	0.999	0.001
Q44.6 Cystic disease of liver	0.000	0.999	0.001
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
T19.1 Foreign body in bladder	0.001	0.999	0.000
Y54.9 Mineral salts, not elsewhere classified	0.000	0.999	0.001
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.999	0.001
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.999	0.001
E26 Hyperaldosteronism	0.001	0.999	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.999	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.999	0.000
E24.1 Nelson's syndrome	0.001	0.999	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
O86.8 Other specified puerperal infections	0.000	0.999	0.001
S32.5 Fracture of pubis	0.000	0.999	0.001
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.001	0.999	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.001	0.999	0.000
C31 Malignant neoplasm of accessory sinuses	0.001	0.999	0.000
T19 Foreign body in genito-urinary tract	0.001	0.999	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.999	0.000
E89.2 Postprocedural hypoparathyroidism	0.001	0.999	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.999	0.001
T19.2 Foreign body in vulva and vagina	0.001	0.999	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
W10.8 Other specified place	0.000	0.999	0.001
B35.1 Tinea unguium	0.001	0.999	0.000
E26.8 Other hyperaldosteronism	0.001	0.999	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.999	0.001
O86.3 Other genito-urinary tract infections following delivery	0.000	0.999	0.001
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
T15.1 Foreign body in conjunctival sac	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.000	0.999	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.999	0.001
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
C31.9 Accessory sinus, unspecified	0.001	0.999	0.000
C31.8 Overlapping lesion of accessory sinuses	0.001	0.999	0.000
C31.3 Sphenoidal sinus	0.001	0.999	0.000
C31.2 Frontal sinus	0.001	0.999	0.000
C31.1 Ethmoidal sinus	0.001	0.999	0.000
C39.9 Ill-defined sites within the respiratory system	0.001	0.999	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.001	0.999	0.000
C39.0 Upper respiratory tract, part unspecified	0.001	0.999	0.000
E80.1 Porphyria cutanea tarda	0.000	0.999	0.001
F45.8 Other somatoform disorders	0.001	0.999	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.001	0.999	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.001	0.999	0.000
T19.3 Foreign body in uterus [any part]	0.001	0.999	0.000
T19.0 Foreign body in urethra	0.001	0.999	0.000
T40.6 Other and unspecified narcotics	0.001	0.999	0.000
W10.6 Industrial and construction area	0.000	0.999	0.001
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
B97 Viral agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.999	0.001
M79.52 Residual foreign body in soft tissue (Upper arm)	0.001	0.999	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.001	0.999	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.001	0.999	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.999	0.001
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C32.1 Supraglottis	0.001	0.999	0.000
C32.0 Glottis	0.001	0.999	0.000
E24.9 Cushing's syndrome, unspecified	0.001	0.999	0.000
N36.1 Urethral diverticulum	0.001	0.999	0.000
O86.1 Other infection of genital tract following delivery	0.000	0.999	0.001
R41.2 Retrograde amnesia	0.000	0.999	0.001
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
Z11.5 Special screening examination for other viral diseases	0.001	0.999	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
C37 Malignant neoplasm of thymus	0.001	0.999	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.999	0.001
H90 Conductive and sensorineural hearing loss	0.000	0.999	0.001
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C31.0 Maxillary sinus	0.001	0.999	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.001	0.999	0.000
M79.5 Residual foreign body in soft tissue	0.001	0.999	0.000
T40.3 Methadone	0.001	0.999	0.000
B99 Other and unspecified infectious diseases	0.000	0.999	0.001
E28 Ovarian dysfunction	0.001	0.999	0.000
T15 Foreign body on external eye	0.001	0.999	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.999	0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.001	0.999	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.001	0.999	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.001	0.999	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.001	0.999	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.001	0.999	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.999	0.001
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
G03.9 Meningitis, unspecified	0.001	0.999	0.000
O86.2 Urinary tract infection following delivery	0.000	0.999	0.001
T15.8 Foreign body in other and multiple parts of external eye	0.001	0.999	0.000
T40.5 Cocaine	0.001	0.999	0.000
Y54.5 Other diuretics	0.000	0.999	0.001
C32 Malignant neoplasm of larynx	0.001	0.999	0.000
C33 Malignant neoplasm of trachea	0.001	0.999	0.000
I27 Other pulmonary heart diseases	0.001	0.999	0.000
L11 Other acantholytic disorders	0.000	0.999	0.001
C32.8 Overlapping lesion of larynx	0.001	0.999	0.000
C32.2 Subglottis	0.001	0.999	0.000
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
I27.1 Kyphoscoliotic heart disease	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations