TreeWAS – Variant ID: rs7188445

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04 Other non-toxic goitre	0.980	0.020	0.000
E04.9 Non-toxic goitre, unspecified	0.980	0.020	0.000
E04.2 Non-toxic multinodular goitre	0.979	0.021	0.000
E00-E07 Disorders of thyroid gland	0.904	0.096	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.862	0.138	0.000
E07 Other disorders of thyroid	0.841	0.159	0.000
E05.8 Other thyrotoxicosis	0.796	0.204	0.000
E05.9 Thyrotoxicosis, unspecified	0.775	0.225	0.000
E07.9 Disorder of thyroid, unspecified	0.758	0.242	0.000
E04.0 Non-toxic diffuse goitre	0.751	0.249	0.000
E07.8 Other specified disorders of thyroid	0.710	0.290	0.000
E04.8 Other specified non-toxic goitre	0.703	0.297	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.653	0.347	0.000
E06 Thyroiditis	0.650	0.350	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.648	0.352	0.000
E00 Congenital iodine-deficiency syndrome	0.648	0.352	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.631	0.369	0.000
E05.5 Thyroid crisis or storm	0.618	0.382	0.000
E05.4 Thyrotoxicosis factitia	0.618	0.382	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.618	0.382	0.000
E07.1 Dyshormogenetic goitre	0.603	0.397	0.000
E07.0 Hypersecretion of calcitonin	0.603	0.397	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.591	0.409	0.000
E04.1 Non-toxic single thyroid nodule	0.574	0.426	0.000
E03 Other hypothyroidism	0.541	0.459	0.000
E06.3 Autoimmune thyroiditis	0.541	0.459	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.539	0.461	0.000
E06.5 Other chronic thyroiditis	0.466	0.534	0.000
E06.4 Drug-induced thyroiditis	0.466	0.534	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.466	0.534	0.000
E06.0 Acute thyroiditis	0.466	0.534	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.465	0.535	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.465	0.535	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.465	0.535	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.465	0.535	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.465	0.535	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.465	0.535	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.465	0.535	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.465	0.535	0.000
E06.1 Subacute thyroiditis	0.448	0.551	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.430	0.570	0.000
E03.8 Other specified hypothyroidism	0.422	0.578	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.409	0.591	0.000
E03.5 Myxoedema coma	0.388	0.612	0.000
E03.4 Atrophy of thyroid (acquired)	0.388	0.612	0.000
E03.3 Postinfectious hypothyroidism	0.388	0.612	0.000
E03.1 Congenital hypothyroidism without goitre	0.388	0.612	0.000
E06.9 Thyroiditis, unspecified	0.370	0.630	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.327	0.673	0.000
K44 Diaphragmatic hernia	0.158	0.842	0.000
K44.1 Diaphragmatic hernia with gangrene	0.120	0.880	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.116	0.884	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.043	0.957	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.958	0.042
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.027	0.973	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.022	0.978	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.987	0.013
S19.9 Unspecified injury of neck	0.013	0.987	0.000
E89.0 Postprocedural hypothyroidism	0.013	0.987	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.989	0.011
S20 Superficial injury of thorax	0.000	0.989	0.011
N45 Orchitis and epididymitis	0.010	0.990	0.000
S20.2 Contusion of thorax	0.000	0.990	0.010
G35 Multiple sclerosis	0.000	0.990	0.010
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.991	0.009
E03.9 Hypothyroidism, unspecified	0.009	0.991	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.991	0.009
S27 Injury of other and unspecified intrathoracic organs	0.000	0.991	0.009
S20.1 Other and unspecified superficial injuries of breast	0.000	0.991	0.009
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.009	0.991	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.009	0.991	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.009	0.991	0.000
S27.0 Traumatic pneumothorax	0.000	0.992	0.008
R10.2 Pelvic and perineal pain	0.008	0.992	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.992	0.008
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.992	0.008
S20.7 Multiple superficial injuries of thorax	0.000	0.992	0.008
S20.0 Contusion of breast	0.000	0.992	0.008
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.008	0.992	0.000
L50.9 Urticaria, unspecified	0.008	0.992	0.000
S20-S29 Injuries to the thorax	0.000	0.992	0.008
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.992	0.008
B44.9 Aspergillosis, unspecified	0.007	0.993	0.000
S27.3 Other injuries of lung	0.000	0.993	0.007
E89.2 Postprocedural hypoparathyroidism	0.007	0.993	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.993	0.007
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
K62.3 Rectal prolapse	0.000	0.993	0.007
S20.4 Other superficial injuries of back wall of thorax	0.000	0.993	0.007
S27.1 Traumatic haemothorax	0.000	0.993	0.007
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.993	0.007
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.007	0.993	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.993	0.007
S27.7 Multiple injuries of intrathoracic organs	0.000	0.993	0.007
S27.6 Injury of pleura	0.000	0.993	0.007
S27.5 Injury of thoracic trachea	0.000	0.993	0.007
S27.4 Injury of bronchus	0.000	0.993	0.007
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.993	0.007
N99.4 Postprocedural pelvic peritoneal adhesions	0.007	0.993	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.993	0.007
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.006	0.993	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.006	0.993	0.000
E89.5 Postprocedural testicular hypofunction	0.006	0.993	0.000
E89.1 Postprocedural hypoinsulinaemia	0.006	0.993	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.007	0.993	0.000
E11.5 With peripheral circulatory complications	0.000	0.993	0.007
S19 Other and unspecified injuries of neck	0.006	0.994	0.000
V18.3 Person injured while boarding or alighting	0.000	0.994	0.006
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.006	0.994	0.000
E89.3 Postprocedural hypopituitarism	0.006	0.994	0.000
S20.3 Other superficial injuries of front wall of thorax	0.000	0.994	0.006
V18.1 Passenger injured in nontraffic accident	0.000	0.994	0.006
S29 Other and unspecified injuries of thorax	0.000	0.994	0.006
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.994	0.006
V18.4 Driver injured in traffic accident	0.000	0.994	0.006
V18.5 Passenger injured in traffic accident	0.000	0.994	0.006
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.994	0.006
S21 Open wound of thorax	0.000	0.994	0.006
Chapter IV Endocrine, nutritional and metabolic diseases	0.006	0.994	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.994	0.006
S25 Injury of blood vessels of thorax	0.000	0.994	0.006
S24 Injury of nerves and spinal cord at thorax level	0.000	0.994	0.006
Z75 Problems related to medical facilities and other health care	0.000	0.994	0.006
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.994	0.006
T83.1 Mechanical complication of other urinary devices and implants	0.006	0.994	0.000
B44.1 Other pulmonary aspergillosis	0.006	0.994	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.994	0.006
B44 Aspergillosis	0.006	0.994	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.006	0.994	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.005	0.995	0.000
S26 Injury of heart	0.000	0.995	0.005
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.995	0.005
M67.1 Other contracture of tendon (sheath)	0.000	0.995	0.005
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.005	0.995	0.000
N99.5 Malfunction of external stoma of urinary tract	0.005	0.995	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.005	0.995	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.995	0.005
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.995	0.005
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.995	0.005
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.995	0.005
D34 Benign neoplasm of thyroid gland	0.005	0.995	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.005	0.995	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.005	0.995	0.000
N48.1 Balanoposthitis	0.000	0.995	0.005
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.995	0.005
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.995	0.005
E89.4 Postprocedural ovarian failure	0.005	0.995	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.995	0.005
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.995	0.005
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.995	0.005
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.995	0.005
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.995	0.005
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.995	0.005
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.995	0.005
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.995	0.005
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.995	0.005
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.995	0.005
N99.0 Postprocedural renal failure	0.005	0.995	0.000
N81.6 Rectocele	0.005	0.995	0.000
S21.1 Open wound of front wall of thorax	0.000	0.995	0.005
S19.7 Multiple injuries of neck	0.005	0.995	0.000
S29.9 Unspecified injury of thorax	0.000	0.995	0.005
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.005	0.995	0.000
S23.4 Sprain and strain of ribs and sternum	0.000	0.995	0.005
S21.2 Open wound of back wall of thorax	0.000	0.995	0.005
N99.1 Postprocedural urethral stricture	0.005	0.995	0.000
N99.2 Postprocedural adhesions of vagina	0.005	0.995	0.000
M67 Other disorders of synovium and tendon	0.000	0.995	0.005
E27 Other disorders of adrenal gland	0.005	0.995	0.000
S06.2 Diffuse brain injury	0.000	0.995	0.005
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.995	0.004
S23.3 Sprain and strain of thoracic spine	0.000	0.995	0.004
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.995	0.004
S23.1 Dislocation of thoracic vertebra	0.000	0.995	0.004
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.995	0.004
S29.7 Multiple injuries of thorax	0.000	0.995	0.004
S29.0 Injury of muscle and tendon at thorax level	0.000	0.995	0.004
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.995	0.004
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.995	0.004
S21.8 Open wound of other parts of thorax	0.000	0.995	0.004
S21.7 Multiple open wounds of thoracic wall	0.000	0.995	0.004
S21.0 Open wound of breast	0.000	0.995	0.004
S29.8 Other specified injuries of thorax	0.000	0.995	0.004
R93 Abnormal findings on diagnostic imaging of other body structures	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.995	0.000
S24.6 Injury of unspecified nerve of thorax	0.000	0.995	0.004
S24.5 Injury of other nerves of thorax	0.000	0.995	0.004
S24.4 Injury of thoracic sympathetic nerves	0.000	0.995	0.004
S24.3 Injury of peripheral nerves of thorax	0.000	0.995	0.004
S24.2 Injury of nerve root of thoracic spine	0.000	0.995	0.004
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.995	0.004
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.995	0.004
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.995	0.004
S25.8 Injury of other blood vessels of thorax	0.000	0.995	0.004
S25.7 Injury of multiple blood vessels of thorax	0.000	0.995	0.004
S25.5 Injury of intercostal blood vessels	0.000	0.995	0.004
S25.4 Injury of pulmonary blood vessels	0.000	0.995	0.004
S25.3 Injury of innominate or subclavian vein	0.000	0.995	0.004
S25.2 Injury of superior vena cava	0.000	0.995	0.004
S25.1 Injury of innominate or subclavian artery	0.000	0.995	0.004
S25.0 Injury of thoracic aorta	0.000	0.995	0.004
S28.1 Traumatic amputation of part of thorax	0.000	0.995	0.004
S28.0 Crushed chest	0.000	0.995	0.004
M11.26 Other chondrocalcinosis (Lower leg)	0.004	0.996	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.996	0.004
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
S19.8 Other specified injuries of neck	0.004	0.996	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.004	0.996	0.000
B44.8 Other forms of aspergillosis	0.004	0.996	0.000
B44.7 Disseminated aspergillosis	0.004	0.996	0.000
B44.2 Tonsillar aspergillosis	0.004	0.996	0.000
B44.0 Invasive pulmonary aspergillosis	0.004	0.996	0.000
K10.8 Other specified diseases of jaws	0.000	0.996	0.004
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.004	0.996	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.004	0.996	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.004	0.996	0.000
S26.9 Injury of heart, unspecified	0.000	0.996	0.004
S26.0 Injury of heart with haemopericardium	0.000	0.996	0.004
Z75.0 Medical services not available in home	0.000	0.996	0.004
L50 Urticaria	0.004	0.996	0.000
S21.9 Open wound of thorax, part unspecified	0.000	0.996	0.004
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
T83.2 Mechanical complication of graft of urinary organ	0.004	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.996	0.004
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
M67.4 Ganglion	0.000	0.996	0.004
M67.0 Short Achilles tendon (acquired)	0.000	0.996	0.004
C22.1 Intrahepatic bile duct carcinoma	0.004	0.996	0.000
Z93.2 Ileostomy status	0.000	0.996	0.004
S26.8 Other injuries of heart	0.000	0.996	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.996	0.000
E24.8 Other Cushing's syndrome	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
E50-E64 Other nutritional deficiencies	0.004	0.996	0.000
Z75.8 Other problems related to medical facilities and other health care	0.000	0.996	0.003
Z75.5 Holiday relief care	0.000	0.996	0.003
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.996	0.001
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.004	0.996	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.996	0.004
M67.3 Transient synovitis	0.000	0.996	0.004
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.003	0.996	0.000
E27.0 Other adrenocortical overactivity	0.003	0.996	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.996	0.003
C22.0 Liver cell carcinoma	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.003	0.996	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.004	0.996	0.000
E27.2 Addisonian crisis	0.003	0.996	0.000
L50.8 Other urticaria	0.003	0.996	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.996	0.004
J38.4 Oedema of larynx	0.000	0.996	0.004
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.996	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.997	0.003
I49.4 Other and unspecified premature depolarisation	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
N99-N99 Other disorders of the genitourinary system	0.003	0.997	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.003	0.997	0.000
M67.43 Ganglion, wrist	0.000	0.997	0.003
E53.8 Deficiency of other specified B group vitamins	0.003	0.997	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.997	0.003
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.997	0.003
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.997	0.003
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.997	0.003
L50.6 Contact urticaria	0.003	0.997	0.000
L50.5 Cholinergic urticaria	0.003	0.997	0.000
L50.4 Vibratory urticaria	0.003	0.997	0.000
L50.3 Dermatographic urticaria	0.003	0.997	0.000
L50.2 Urticaria due to cold and heat	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.000	0.997	0.003
E25 Adrenogenital disorders	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
R82.9 Other and unspecified abnormal finding in urine	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.000	0.997	0.003
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
M67.49 Ganglion, multiple sites	0.000	0.997	0.003
M67.45 Ganglion, hip	0.000	0.997	0.003
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.997	0.003
K40-K46 Hernia	0.003	0.997	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.003	0.997	0.000
E51 Thiamine deficiency	0.003	0.997	0.000
S06 Intracranial injury	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
N71.1 Chronic inflammatory disease of uterus	0.003	0.997	0.000
R41.2 Retrograde amnesia	0.003	0.997	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.997	0.003
E58 Dietary calcium deficiency	0.003	0.997	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.003	0.997	0.000
E63 Other nutritional deficiencies	0.003	0.997	0.000
E50 Vitamin A deficiency	0.003	0.997	0.000
E60 Dietary zinc deficiency	0.003	0.997	0.000
E59 Dietary selenium deficiency	0.003	0.997	0.000
E54 Ascorbic acid deficiency	0.003	0.997	0.000
E52 Niacin deficiency [pellagra]	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
E56 Other vitamin deficiencies	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
E15 Nondiabetic hypoglycaemic coma	0.002	0.997	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
L50.1 Idiopathic urticaria	0.003	0.997	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.997	0.003
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.000	0.997	0.003
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.000	0.997	0.003
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.000	0.997	0.003
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.000	0.997	0.003
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.000	0.997	0.003
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.000	0.997	0.003
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.000	0.997	0.003
E28 Ovarian dysfunction	0.003	0.997	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.000	0.997	0.003
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
S42.20 Fracture of upper end of humerus (closed)	0.000	0.997	0.003
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
S42 Fracture of shoulder and upper arm	0.000	0.997	0.003
Z75.2 Other waiting period for investigation and treatment	0.001	0.997	0.002
S42.31 Fracture of shaft of humerus (open)	0.000	0.997	0.003
S42.2 Fracture of upper end of humerus	0.000	0.997	0.003
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
E11.4 With neurological complications	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.997	0.000
E42 Marasmic kwashiorkor	0.002	0.997	0.000
E41 Nutritional marasmus	0.002	0.997	0.000
E40 Kwashiorkor	0.002	0.997	0.000
L50.0 Allergic urticaria	0.003	0.997	0.000
S73.0 Dislocation of hip	0.003	0.997	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.001	0.997	0.002
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.997	0.003
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
S42.1 Fracture of scapula	0.000	0.997	0.003
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.000	0.997	0.003
E51.2 Wernicke's encephalopathy	0.002	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.997	0.000
M11.2 Other chondrocalcinosis	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.002	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.997	0.000
E25.8 Other adrenogenital disorders	0.002	0.997	0.000
S06.4 Epidural haemorrhage	0.000	0.997	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.003	0.997	0.000
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
C22.9 Liver, unspecified	0.003	0.997	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.002	0.997	0.000
E34.0 Carcinoid syndrome	0.002	0.997	0.000
S06.8 Other intracranial injuries	0.000	0.997	0.002
C22.7 Other specified carcinomas of liver	0.002	0.997	0.000
C22.4 Other sarcomas of liver	0.002	0.997	0.000
C22.3 Angiosarcoma of liver	0.002	0.997	0.000
C22.2 Hepatoblastoma	0.002	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.997	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.997	0.000
E51.1 Beriberi	0.002	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.997	0.002
S06.1 Traumatic cerebral oedema	0.000	0.997	0.002
E28.3 Primary ovarian failure	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
M47.1 Other spondylosis with myelopathy	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
R82 Other abnormal findings in urine	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.998	0.002
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S42.21 Fracture of upper end of humerus (open)	0.000	0.998	0.002
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.001	0.998	0.001
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.998	0.002
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
E44.1 Mild protein-energy malnutrition	0.002	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.002	0.998	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.998	0.002
I70 Atherosclerosis	0.000	0.998	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
I70.1 Atherosclerosis of renal artery	0.000	0.998	0.002
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
S42.11 Fracture of scapula (open)	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
L50-L54 Urticaria and erythema	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
C44.1 Skin of eyelid, including canthus	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.000	0.998	0.002
K42 Umbilical hernia	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
C81.1 Nodular sclerosis	0.000	0.998	0.002
R82.1 Myoglobinuria	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.998	0.002
C50.2 Upper-inner quadrant of breast	0.002	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.002	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.998	0.002
E55 Vitamin D deficiency	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
K42.9 Umbilical hernia without obstruction or gangrene	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.002
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.002
N48.4 Impotence of organic origin	0.000	0.998	0.002
R82.4 Acetonuria	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations