TreeWAS – Variant ID: rs7195486

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J18.9 Pneumonia, unspecified	0.000	0.701	0.299
J18 Pneumonia, organism unspecified	0.000	0.872	0.128
J18.0 Bronchopneumonia, unspecified	0.000	0.883	0.117
J18.8 Other pneumonia, organism unspecified	0.000	0.904	0.096
J18.2 Hypostatic pneumonia, unspecified	0.000	0.908	0.092
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.033	0.967	0.000
G44.2 Tension-type headache	0.026	0.974	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.021	0.979	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.020	0.980	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
T39.0 Salicylates	0.019	0.981	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.018	0.982	0.000
K91.4 Colostomy and enterostomy malfunction	0.017	0.983	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.016	0.984	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.015	0.985	0.000
W19.9 Unspecified place	0.000	0.985	0.015
K91.5 Postcholecystectomy syndrome	0.015	0.985	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.014	0.986	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.014	0.986	0.000
T39.1 4-Aminophenol derivatives	0.014	0.986	0.000
T39.4 Antirheumatics, not elsewhere classified	0.014	0.986	0.000
T39.2 Pyrazolone derivatives	0.014	0.986	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.013	0.987	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.012	0.987	0.000
H43.8 Other disorders of vitreous body	0.000	0.988	0.012
K91.1 Postgastric surgery syndromes	0.011	0.989	0.000
D51 Vitamin B12 deficiency anaemia	0.010	0.990	0.000
K07.6 Temporomandibular joint disorders	0.010	0.990	0.000
H43 Disorders of vitreous body	0.000	0.991	0.009
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.009	0.991	0.000
H44.2 Degenerative myopia	0.000	0.991	0.009
H44 Disorders of globe	0.000	0.991	0.009
J09-J18 Influenza and pneumonia	0.000	0.992	0.008
G93.0 Cerebral cysts	0.008	0.992	0.000
G93.2 Benign intracranial hypertension	0.008	0.992	0.000
G93 Other disorders of brain	0.008	0.992	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.008	0.992	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.008	0.992	0.000
H43.3 Other vitreous opacities	0.000	0.992	0.008
H43-H45 Disorders of vitreous body and globe	0.000	0.992	0.008
H43.2 Crystalline deposits in vitreous body	0.000	0.992	0.008
N89.9 Noninflammatory disorder of vagina, unspecified	0.008	0.992	0.000
K07.3 Anomalies of tooth position	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.008	0.992	0.000
H44.1 Other endophthalmitis	0.000	0.992	0.007
D51.8 Other vitamin B12 deficiency anaemias	0.007	0.993	0.000
D51.2 Transcobalamin II deficiency	0.007	0.993	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.007	0.993	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
H44.0 Purulent endophthalmitis	0.000	0.993	0.007
M81.9 Osteoporosis, unspecified	0.007	0.993	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
K91.3 Postoperative intestinal obstruction	0.007	0.993	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.993	0.007
H43.0 Vitreous prolapse	0.000	0.993	0.007
K07 Dentofacial anomalies [including malocclusion]	0.007	0.993	0.000
G93.4 Encephalopathy, unspecified	0.007	0.993	0.000
G44 Other headache syndromes	0.007	0.993	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T40.2 Other opioids	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
H44.9 Disorder of globe, unspecified	0.000	0.993	0.006
H44.8 Other disorders of globe	0.000	0.993	0.006
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.993	0.006
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.993	0.006
H44.5 Degenerated conditions of globe	0.000	0.993	0.006
H44.3 Other degenerative disorders of globe	0.000	0.993	0.006
G93.6 Cerebral oedema	0.006	0.994	0.000
H44.4 Hypotony of eye	0.000	0.994	0.006
G93.5 Compression of brain	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.994	0.006
J09 Influenza due to certain identified influenza virus	0.000	0.994	0.006
G90-G99 Other disorders of the nervous system	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
M81.98 Osteoporosis, unspecified (Other)	0.006	0.994	0.000
G93.7 Reye's syndrome	0.006	0.994	0.000
M81 Osteoporosis without pathological fracture	0.006	0.994	0.000
M81.4 Drug-induced osteoporosis	0.006	0.994	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.994	0.006
T36.0 Penicillins	0.006	0.994	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.000	0.994	0.006
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.006	0.994	0.000
G90 Disorders of autonomic nervous system	0.006	0.994	0.000
G96 Other disorders of central nervous system	0.006	0.994	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.994	0.006
J10 Influenza due to identified influenza virus	0.000	0.994	0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.994	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.994	0.005
M81.93 Osteoporosis, unspecified (Forearm)	0.005	0.994	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.006	0.994	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.005	0.994	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.005	0.994	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.005	0.994	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.994	0.000
E89.0 Postprocedural hypothyroidism	0.005	0.995	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.995	0.005
N89 Other noninflammatory disorders of vagina	0.005	0.995	0.000
G95.0 Syringomyelia and syringobulbia	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.995	0.000
T50.5 Appetite depressants	0.005	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.005	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.995	0.000
J12 Viral pneumonia, not elsewhere classified	0.000	0.995	0.005
J17 Pneumonia in diseases classified elsewhere	0.000	0.995	0.005
T46.1 Calcium-channel blockers	0.005	0.995	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.995	0.005
G96.1 Disorders of meninges, not elsewhere classified	0.005	0.995	0.000
K07.0 Major anomalies of jaw size	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.005	0.995	0.000
G44.1 Vascular headache, not elsewhere classified	0.005	0.995	0.000
K07.8 Other dentofacial anomalies	0.005	0.995	0.000
K07.5 Dentofacial functional abnormalities	0.005	0.995	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.995	0.005
K07.2 Anomalies of dental arch relationship	0.005	0.995	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.005	0.995	0.000
K07.9 Dentofacial anomaly, unspecified	0.005	0.995	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.995	0.005
G95 Other diseases of spinal cord	0.005	0.995	0.000
N89.5 Stricture and atresia of vagina	0.005	0.995	0.000
J11 Influenza, virus not identified	0.000	0.995	0.005
M81.2 Osteoporosis of disuse	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
G44.3 Chronic posttraumatic headache	0.005	0.995	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.005	0.995	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.995	0.005
G90.0 Idiopathic peripheral autonomic neuropathy	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
G96.8 Other specified disorders of central nervous system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.995	0.005
G98 Other disorders of nervous system, not elsewhere classified	0.005	0.995	0.000
G44.0 Cluster headache syndrome	0.005	0.995	0.000
N89.0 Mild vaginal dysplasia	0.005	0.995	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.005	0.995	0.000
K07.4 Malocclusion, unspecified	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.005	0.995	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.005	0.995	0.000
M25.4 Effusion of joint	0.000	0.995	0.005
M81.0 Postmenopausal osteoporosis	0.005	0.995	0.000
G92 Toxic encephalopathy	0.005	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
M81.8 Other osteoporosis	0.005	0.995	0.000
M81.6 Localised osteoporosis [Lequesne]	0.005	0.995	0.000
M81.5 Idiopathic osteoporosis	0.005	0.995	0.000
M81.1 Postoophorectomy osteoporosis	0.005	0.995	0.000
J14 Pneumonia due to Haemophilus influenzae	0.000	0.995	0.004
M81.48 Drug-induced osteoporosis (Other)	0.004	0.995	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.004	0.995	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.004	0.995	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.004	0.995	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.004	0.995	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.004	0.995	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.004	0.995	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.004	0.995	0.000
J15.5 Pneumonia due to Escherichia coli	0.000	0.995	0.005
N89.1 Moderate vaginal dysplasia	0.005	0.995	0.000
G93.9 Disorder of brain, unspecified	0.005	0.995	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.995	0.004
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.995	0.004
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.995	0.004
M81.20 Osteoporosis of disuse (Multiple sites)	0.004	0.995	0.000
J16.0 Chlamydial pneumonia	0.000	0.995	0.004
G94 Other disorders of brain in diseases classified elsewhere	0.004	0.995	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.004	0.996	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
G91 Hydrocephalus	0.004	0.996	0.000
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.996	0.004
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.996	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.996	0.004
C43.5 Malignant melanoma of trunk	0.004	0.996	0.000
M25.40 Effusion of joint (Multiple sites)	0.000	0.996	0.004
G90.8 Other disorders of autonomic nervous system	0.004	0.996	0.000
G90.4 Autonomic dysreflexia	0.004	0.996	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.004	0.996	0.000
J11.0 Influenza with pneumonia, virus not identified	0.000	0.996	0.004
J17.3 Pneumonia in parasitic diseases	0.000	0.996	0.004
G96.9 Disorder of central nervous system, unspecified	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
G93.3 Postviral fatigue syndrome	0.004	0.996	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.000	0.996	0.004
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.996	0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.004	0.996	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.004	0.996	0.000
J15.8 Other bacterial pneumonia	0.000	0.996	0.004
J15.3 Pneumonia due to streptococcus, group B	0.000	0.996	0.004
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.996	0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.004	0.996	0.000
N89.7 Haematocolpos	0.004	0.996	0.000
N89.4 Leukoplakia of vagina	0.004	0.996	0.000
N89.3 Dysplasia of vagina, unspecified	0.004	0.996	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.004	0.996	0.000
G90.2 Horner's syndrome	0.004	0.996	0.000
J12.8 Other viral pneumonia	0.000	0.996	0.004
J12.3 Human metapneumovirus pneumonia	0.000	0.996	0.004
J12.2 Parainfluenza virus pneumonia	0.000	0.996	0.004
J12.1 Respiratory syncytial virus pneumonia	0.000	0.996	0.004
J12.0 Adenoviral pneumonia	0.000	0.996	0.004
J15.4 Pneumonia due to other streptococci	0.000	0.996	0.004
J17.8 Pneumonia in other diseases classified elsewhere	0.000	0.996	0.004
J15.1 Pneumonia due to Pseudomonas	0.000	0.996	0.004
I22.9 Subsequent myocardial infarction of unspecified site	0.004	0.996	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.996	0.004
M96.5 Postradiation scoliosis	0.000	0.996	0.004
M96.4 Postsurgical lordosis	0.000	0.996	0.004
M96.3 Postlaminectomy kyphosis	0.000	0.996	0.004
M96.2 Postradiation kyphosis	0.000	0.996	0.004
G95.2 Cord compression, unspecified	0.004	0.996	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.004	0.996	0.000
G97.8 Other postprocedural disorders of nervous system	0.004	0.996	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.004	0.996	0.000
G91.0 Communicating hydrocephalus	0.004	0.996	0.000
J11.8 Influenza with other manifestations, virus not identified	0.000	0.996	0.004
M81.29 Osteoporosis of disuse (Site unspecified)	0.004	0.996	0.000
M81.28 Osteoporosis of disuse (Other)	0.004	0.996	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.004	0.996	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.004	0.996	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.004	0.996	0.000
M81.24 Osteoporosis of disuse (Hand)	0.004	0.996	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.004	0.996	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.004	0.996	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
M25.44 Effusion of joint (Hand)	0.000	0.996	0.004
N94.6 Dysmenorrhoea, unspecified	0.000	0.996	0.004
E89.3 Postprocedural hypopituitarism	0.004	0.996	0.000
J17.2 Pneumonia in mycoses	0.000	0.996	0.004
G95.8 Other specified diseases of spinal cord	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
C43.9 Malignant melanoma of skin, unspecified	0.004	0.996	0.000
T51.9 Alcohol, unspecified	0.004	0.996	0.000
M25.43 Effusion of joint (Forearm)	0.000	0.996	0.004
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.004	0.996	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.004	0.996	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.004	0.996	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.004	0.996	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.004	0.996	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.004	0.996	0.000
N89.6 Tight hymenal ring	0.004	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.996	0.004
M25.49 Effusion of joint (Site unspecified)	0.000	0.996	0.004
M25.48 Effusion of joint (Other)	0.000	0.996	0.004
M25.41 Effusion of joint (Shoulder region)	0.000	0.996	0.004
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.996	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.996	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.996	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.996	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.996	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.996	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.996	0.000
E89.4 Postprocedural ovarian failure	0.004	0.996	0.000
E89.2 Postprocedural hypoparathyroidism	0.004	0.996	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.996	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.996	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.996	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.996	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.996	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.996	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.996	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.996	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.996	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.996	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.996	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.996	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.996	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.996	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.996	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.996	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.996	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.996	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.996	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.996	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.996	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.996	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.996	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.996	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.996	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.996	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.996	0.000
M81.88 Other osteoporosis (Other)	0.003	0.996	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.996	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.996	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.996	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.996	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.996	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.996	0.000
G90.3 Multisystem degeneration	0.003	0.996	0.000
M25.42 Effusion of joint (Upper arm)	0.000	0.996	0.003
G44.8 Other specified headache syndromes	0.003	0.996	0.000
G91.2 Normal-pressure hydrocephalus	0.003	0.996	0.000
C43.4 Malignant melanoma of scalp and neck	0.003	0.996	0.000
G91.8 Other hydrocephalus	0.003	0.996	0.000
G94.1 Hydrocephalus in neoplastic disease	0.003	0.996	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.003	0.996	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
I22.8 Subsequent myocardial infarction of other sites	0.003	0.997	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.997	0.003
G91.3 Posttraumatic hydrocephalus, unspecified	0.003	0.997	0.000
G95.1 Vascular myelopathies	0.003	0.997	0.000
C43 Malignant melanoma of skin	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
E80.4 Gilbert's syndrome	0.003	0.997	0.000
J12.9 Viral pneumonia, unspecified	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.997	0.003
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.997	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.997	0.000
E89.5 Postprocedural testicular hypofunction	0.003	0.997	0.000
E89.1 Postprocedural hypoinsulinaemia	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.997	0.003
N89.8 Other specified noninflammatory disorders of vagina	0.003	0.997	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.997	0.003
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.997	0.003
G93.8 Other specified disorders of brain	0.003	0.997	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
H43.1 Vitreous haemorrhage	0.000	0.997	0.003
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
G91.1 Obstructive hydrocephalus	0.003	0.997	0.000
T40.6 Other and unspecified narcotics	0.003	0.997	0.001
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
G95.9 Disease of spinal cord, unspecified	0.003	0.997	0.000
T51 Toxic effect of alcohol	0.003	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
K22.7 Barrett's oesophagus	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.997	0.002
W19 Unspecified fall	0.000	0.997	0.003
C44.2 Skin of ear and external auricular canal	0.000	0.997	0.003
H53.0 Amblyopia ex anopsia	0.003	0.997	0.000
C43.8 Overlapping malignant melanoma of skin	0.003	0.997	0.000
C43.0 Malignant melanoma of lip	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.003	0.997	0.000
T51.0 Ethanol	0.003	0.997	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.003	0.997	0.000
N39.8 Other specified disorders of urinary system	0.000	0.997	0.003
I22 Subsequent myocardial infarction	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
Q61 Cystic kidney disease	0.000	0.998	0.002
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.002	0.998	0.000
N88 Other noninflammatory disorders of cervix uteri	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
T51.8 Other alcohols	0.002	0.998	0.000
T51.3 Fusel oil	0.002	0.998	0.000
T51.2 2-Propanol	0.002	0.998	0.000
T51.1 Methanol	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.001	0.998	0.002
W19.8 Other specified place	0.000	0.998	0.002
W19.5 Trade and service area	0.000	0.998	0.002
W19.0 Home	0.000	0.998	0.002
W19.7 Farm	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
I67.9 Cerebrovascular disease, unspecified	0.000	0.998	0.002
T63.4 Venom of other arthropods	0.002	0.998	0.000
W19.1 Residential institution	0.000	0.998	0.002
O03 Spontaneous abortion	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
W07.9 Unspecified place	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
W19.6 Industrial and construction area	0.000	0.998	0.002
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations