TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs721394
log Bayes Factor = 9.98725
Chromosome 6   position 33,117,818  (GRCh37) Explore rs721394 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.013 0.987
E10.1 With ketoacidosis
0.000 0.017 0.983
E00-E07 Disorders of thyroid gland
0.000 0.025 0.975
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.028 0.972
E16 Other disorders of pancreatic internal secretion
0.000 0.039 0.961
E16.2 Hypoglycaemia, unspecified
0.000 0.046 0.954
E10.5 With peripheral circulatory complications
0.000 0.051 0.949
E11 Non-insulin-dependent diabetes mellitus
0.000 0.064 0.936
E06 Thyroiditis
0.000 0.072 0.928
E04 Other non-toxic goitre
0.000 0.076 0.924
E50-E64 Other nutritional deficiencies
0.000 0.089 0.911
E03 Other hypothyroidism
0.000 0.090 0.910
E10.2 With renal complications
0.000 0.090 0.910
E11.4 With neurological complications
0.000 0.115 0.885
E06.3 Autoimmune thyroiditis
0.000 0.117 0.883
E03.9 Hypothyroidism, unspecified
0.000 0.125 0.875
E11.1 With ketoacidosis
0.000 0.147 0.853
E04.2 Non-toxic multinodular goitre
0.000 0.149 0.851
E10.6 With other specified complications
0.000 0.153 0.847
E14 Unspecified diabetes mellitus
0.000 0.155 0.845
E04.1 Non-toxic single thyroid nodule
0.000 0.165 0.835
E10.4 With neurological complications
0.000 0.165 0.835
E53 Deficiency of other B group vitamins
0.000 0.177 0.823
E11.3 With ophthalmic complications
0.000 0.178 0.822
E55 Vitamin D deficiency
0.000 0.179 0.821
E14.3 With ophthalmic complications
0.000 0.217 0.783
E53.8 Deficiency of other specified B group vitamins
0.000 0.221 0.779
E55.9 Vitamin D deficiency, unspecified
0.000 0.243 0.757
E10.0 With coma
0.000 0.250 0.750
E06.9 Thyroiditis, unspecified
0.000 0.261 0.738
E11.2 With renal complications
0.000 0.268 0.732
E11.6 With other specified complications
0.000 0.271 0.729
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.278 0.722
E04.0 Non-toxic diffuse goitre
0.000 0.278 0.722
E10.8 With unspecified complications
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E20-E35 Disorders of other endocrine glands
0.000 0.300 0.700
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.301 0.699
E00 Congenital iodine-deficiency syndrome
0.000 0.301 0.699
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.301 0.699
E15 Nondiabetic hypoglycaemic coma
0.000 0.303 0.697
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.307 0.693
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.311 0.689
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.311 0.689
E16.4 Abnormal secretion of gastrin
0.000 0.311 0.689
E16.3 Increased secretion of glucagon
0.000 0.311 0.689
E11.7 With multiple complications
0.000 0.329 0.671
E06.5 Other chronic thyroiditis
0.000 0.334 0.666
E06.4 Drug-induced thyroiditis
0.000 0.334 0.666
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.334 0.666
E06.1 Subacute thyroiditis
0.000 0.334 0.666
E06.0 Acute thyroiditis
0.000 0.334 0.666
E04.8 Other specified non-toxic goitre
0.000 0.337 0.663
E11.8 With unspecified complications
0.000 0.346 0.654
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.347 0.653
E63 Other nutritional deficiencies
0.000 0.347 0.653
E56 Other vitamin deficiencies
0.000 0.347 0.653
E50 Vitamin A deficiency
0.000 0.347 0.653
E60 Dietary zinc deficiency
0.000 0.347 0.653
E59 Dietary selenium deficiency
0.000 0.347 0.653
E58 Dietary calcium deficiency
0.000 0.347 0.653
E54 Ascorbic acid deficiency
0.000 0.347 0.653
E52 Niacin deficiency [pellagra]
0.000 0.347 0.653
E03.5 Myxoedema coma
0.000 0.347 0.652
E03.4 Atrophy of thyroid (acquired)
0.000 0.347 0.652
E03.3 Postinfectious hypothyroidism
0.000 0.347 0.652
E03.1 Congenital hypothyroidism without goitre
0.000 0.347 0.652
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.347 0.652
E20 Hypoparathyroidism
0.000 0.358 0.642
E16.1 Other hypoglycaemia
0.000 0.364 0.636
E11.0 With coma
0.000 0.374 0.626
E51 Thiamine deficiency
0.000 0.379 0.621
E14.1 With ketoacidosis
0.000 0.380 0.619
E27 Other disorders of adrenal gland
0.000 0.386 0.614
E14.8 With unspecified complications
0.000 0.390 0.610
E14.7 With multiple complications
0.000 0.394 0.606
E14.6 With other specified complications
0.000 0.394 0.606
E14.5 With peripheral circulatory complications
0.000 0.394 0.606
E14.2 Withrenal complications
0.000 0.394 0.606
E14.0 With coma
0.000 0.394 0.606
E20.9 Hypoparathyroidism, unspecified
0.000 0.400 0.600
E53.1 Pyridoxine deficiency
0.000 0.410 0.590
E53.0 Riboflavin deficiency
0.000 0.410 0.590
E27.1 Primary adrenocortical insufficiency
0.000 0.411 0.589
E55.0 Rickets, active
0.000 0.411 0.589
E14.4 With neurological complications
0.000 0.423 0.577
E65-E68 Obesity and other hyperalimentation
0.000 0.471 0.529
E13 Other specified diabetes mellitus
0.001 0.479 0.520
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.498 0.502
E32 Diseases of thymus
0.000 0.498 0.502
E31 Polyglandular dysfunction
0.000 0.498 0.502
E30 Disorders of puberty, not elsewhere classified
0.000 0.498 0.502
E25 Adrenogenital disorders
0.000 0.498 0.502
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.499 0.501
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.499 0.501
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.499 0.501
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.499 0.501
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.499 0.501
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.499 0.501
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.499 0.501
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.499 0.501
E40-E46 Malnutrition
0.001 0.500 0.499
E61 Deficiency of other nutrient elements
0.000 0.503 0.497
E53.9 Vitamin B deficiency, unspecified
0.000 0.504 0.496
E26 Hyperaldosteronism
0.000 0.517 0.483
E34 Other endocrine disorders
0.000 0.518 0.482
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.519 0.481
E07 Other disorders of thyroid
0.000 0.520 0.479
E50.9 Vitamin A deficiency, unspecified
0.000 0.532 0.468
E50.8 Other manifestations of vitamin A deficiency
0.000 0.532 0.468
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.532 0.468
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.532 0.468
E50.5 Vitamin A deficiency with night blindness
0.000 0.532 0.468
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.532 0.468
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.532 0.468
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.532 0.468
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.532 0.468
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.532 0.468
E56.9 Vitamin deficiency, unspecified
0.000 0.532 0.468
E56.8 Deficiency of other vitamins
0.000 0.532 0.468
E56.1 Deficiency of vitamin K
0.000 0.532 0.468
E56.0 Deficiency of vitamin E
0.000 0.532 0.468
E63.9 Nutritional deficiency, unspecified
0.000 0.532 0.468
E63.8 Other specified nutritional deficiencies
0.000 0.532 0.468
E63.1 Imbalance of constituents of food intake
0.000 0.532 0.468
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.532 0.468
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.532 0.468
E64.8 Sequelae of other nutritional deficiencies
0.000 0.532 0.468
E64.3 Sequelae of rickets
0.000 0.532 0.468
E64.2 Sequelae of vitamin C deficiency
0.000 0.532 0.468
E64.1 Sequelae of vitamin A deficiency
0.000 0.532 0.468
E64.0 Sequelae of protein-energy malnutrition
0.000 0.532 0.468
E20.8 Other hypoparathyroidism
0.000 0.540 0.460
E20.1 Pseudohypoparathyroidism
0.000 0.540 0.460
E20.0 Idiopathic hypoparathyroidism
0.000 0.540 0.460
E27.2 Addisonian crisis
0.000 0.541 0.459
E29 Testicular dysfunction
0.000 0.545 0.455
E22 Hyperfunction of pituitary gland
0.000 0.546 0.453
E51.9 Thiamine deficiency, unspecified
0.000 0.554 0.445
E51.8 Other manifestations of thiamine deficiency
0.000 0.554 0.445
E51.1 Beriberi
0.000 0.554 0.445
E28 Ovarian dysfunction
0.000 0.555 0.445
E03.8 Other specified hypothyroidism
0.000 0.556 0.444
E04.9 Non-toxic goitre, unspecified
0.000 0.558 0.442
E27.5 Adrenomedullary hyperfunction
0.000 0.559 0.440
E27.0 Other adrenocortical overactivity
0.000 0.559 0.440
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.561 0.439
E14.9 Without complications
0.000 0.563 0.437
E27.9 Disorder of adrenal gland, unspecified
0.000 0.582 0.417
E51.2 Wernicke's encephalopathy
0.000 0.586 0.413
E21.0 Primary hyperparathyroidism
0.000 0.592 0.408
E65 Localised adiposity
0.000 0.608 0.392
E67 Other hyperalimentation
0.000 0.620 0.379
E68 Sequelae of hyperalimentation
0.000 0.620 0.379
E13.8 With unspecified complications
0.001 0.627 0.373
E13.7 With multiple complications
0.001 0.627 0.373
E13.6 With other specified complications
0.001 0.627 0.373
E13.5 With peripheral circulatory complications
0.001 0.627 0.373
E13.4 With neurological complications
0.001 0.627 0.373
E13.3 With ophthalmic complications
0.001 0.627 0.373
E13.2 With renal complications
0.001 0.627 0.373
E13.1 With ketoacidosis
0.001 0.627 0.373
E13.0 With coma
0.001 0.627 0.373
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.629 0.370
E34.0 Carcinoid syndrome
0.000 0.630 0.370
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.639 0.361
E25.9 Adrenogenital disorder, unspecified
0.000 0.640 0.360
E25.8 Other adrenogenital disorders
0.000 0.640 0.360
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.640 0.360
E30.9 Disorder of puberty, unspecified
0.000 0.640 0.360
E30.8 Other disorders of puberty
0.000 0.640 0.360
E30.1 Precocious puberty
0.000 0.640 0.360
E30.0 Delayed puberty
0.000 0.640 0.360
E31.9 Polyglandular dysfunction, unspecified
0.000 0.640 0.360
E31.8 Other polyglandular dysfunction
0.000 0.640 0.360
E31.1 Polyglandular hyperfunction
0.000 0.640 0.360
E31.0 Autoimmune polyglandular failure
0.000 0.640 0.360
E32.9 Disease of thymus, unspecified
0.000 0.640 0.360
E32.8 Other diseases of thymus
0.000 0.640 0.360
E32.1 Abscess of thymus
0.000 0.640 0.360
E32.0 Persistent hyperplasia of thymus
0.000 0.640 0.360
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.640 0.360
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.640 0.360
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.640 0.360
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.641 0.358
E45 Retarded development following protein-energy malnutrition
0.001 0.641 0.358
E43 Unspecified severe protein-energy malnutrition
0.001 0.641 0.358
E42 Marasmic kwashiorkor
0.001 0.641 0.358
E41 Nutritional marasmus
0.001 0.641 0.358
E40 Kwashiorkor
0.001 0.641 0.358
E24 Cushing's syndrome
0.000 0.642 0.358
E61.9 Deficiency of nutrient element, unspecified
0.000 0.644 0.356
E61.8 Deficiency of other specified nutrient elements
0.000 0.644 0.356
E61.7 Deficiency of multiple nutrient elements
0.000 0.644 0.356
E61.6 Vanadium deficiency
0.000 0.644 0.356
E61.5 Molybdenum deficiency
0.000 0.644 0.356
E61.4 Chromium deficiency
0.000 0.644 0.356
E61.3 Manganese deficiency
0.000 0.644 0.356
E61.0 Copper deficiency
0.000 0.644 0.356
E26.0 Primary hyperaldosteronism
0.000 0.645 0.355
E23 Hypofunction and other disorders of pituitary gland
0.000 0.647 0.352
E26.8 Other hyperaldosteronism
0.000 0.654 0.346
E26.1 Secondary hyperaldosteronism
0.000 0.654 0.346
E34.5 Androgen resistance syndrome
0.000 0.654 0.345
E34.4 Constitutional tall stature
0.000 0.654 0.345
E34.3 Short stature, not elsewhere classified
0.000 0.654 0.345
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.654 0.345
E34.1 Other hypersecretion of intestinal hormones
0.000 0.654 0.345
E21.4 Other specified disorders of parathyroid gland
0.000 0.655 0.345
E21.2 Other hyperparathyroidism
0.000 0.655 0.345
E07.1 Dyshormogenetic goitre
0.000 0.656 0.344
E07.0 Hypersecretion of calcitonin
0.000 0.656 0.344
E28.3 Primary ovarian failure
0.000 0.661 0.339
E21.3 Hyperparathyroidism, unspecified
0.000 0.663 0.337
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.670 0.329
E34.9 Endocrine disorder, unspecified
0.000 0.673 0.327
E29.9 Testicular dysfunction, unspecified
0.000 0.674 0.326
E29.8 Other testicular dysfunction
0.000 0.674 0.326
E29.0 Testicular hyperfunction
0.000 0.674 0.326
E07.8 Other specified disorders of thyroid
0.000 0.674 0.325
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.675 0.325
E22.8 Other hyperfunction of pituitary gland
0.000 0.675 0.325
E28.9 Ovarian dysfunction, unspecified
0.000 0.681 0.319
E28.8 Other ovarian dysfunction
0.000 0.681 0.319
E28.1 Androgen excess
0.000 0.681 0.319
E28.0 Oestrogen excess
0.000 0.681 0.319
E27.8 Other specified disorders of adrenal gland
0.000 0.681 0.319
E26.9 Hyperaldosteronism, unspecified
0.000 0.683 0.316
E34.8 Other specified endocrine disorders
0.000 0.686 0.314
E61.2 Magnesium deficiency
0.000 0.690 0.310
E11.5 With peripheral circulatory complications
0.000 0.709 0.291
E22.0 Acromegaly and pituitary gigantism
0.000 0.715 0.285
E23.6 Other disorders of pituitary gland
0.000 0.718 0.282
E29.1 Testicular hypofunction
0.000 0.721 0.278
E61.1 Iron deficiency
0.000 0.727 0.273
E67.8 Other specified hyperalimentation
0.000 0.728 0.272
E67.3 Hypervitaminosis D
0.000 0.728 0.272
E67.2 Megavitamin-B6 syndrome
0.000 0.728 0.272
E67.1 Hypercarotenaemia
0.000 0.728 0.272
E67.0 Hypervitaminosis A
0.000 0.728 0.272
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.729 0.271
E22.1 Hyperprolactinaemia
0.000 0.733 0.267
E23.7 Disorder of pituitary gland, unspecified
0.000 0.739 0.261
E44.1 Mild protein-energy malnutrition
0.001 0.743 0.257
E44.0 Moderate protein-energy malnutrition
0.001 0.743 0.257
E24.8 Other Cushing's syndrome
0.000 0.743 0.257
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.743 0.257
E24.3 Ectopic ACTH syndrome
0.000 0.743 0.257
E24.1 Nelson's syndrome
0.000 0.743 0.257
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.747 0.253
E23.1 Drug-induced hypopituitarism
0.000 0.747 0.253
E24.2 Drug-induced Cushing's syndrome
0.000 0.748 0.251
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.764 0.236
E28.2 Polycystic ovarian syndrome
0.000 0.772 0.228
E24.9 Cushing's syndrome, unspecified
0.000 0.783 0.217
E05.5 Thyroid crisis or storm
0.000 0.805 0.194
E05.4 Thyrotoxicosis factitia
0.000 0.805 0.194
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.805 0.194
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.805 0.194
E24.0 Pituitary-dependent Cushing's disease
0.001 0.810 0.189
E13.9 Without complications
0.001 0.821 0.178
E05.8 Other thyrotoxicosis
0.000 0.826 0.174
E66 Obesity
0.000 0.829 0.171
E23.0 Hypopituitarism
0.000 0.830 0.170
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.832 0.167
E07.9 Disorder of thyroid, unspecified
0.000 0.833 0.166
E46 Unspecified protein-energy malnutrition
0.001 0.849 0.149
E23.2 Diabetes insipidus
0.001 0.857 0.143
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.866 0.134
E05.9 Thyrotoxicosis, unspecified
0.000 0.869 0.131
E66.1 Drug-induced obesity
0.000 0.877 0.123
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.890 0.110
E66.0 Obesity due to excess calories
0.000 0.890 0.109
E66.8 Other obesity
0.000 0.905 0.095
E11.9 Without complications
0.000 0.969 0.031
E70-E90 Metabolic disorders
0.000 0.972 0.028
R20.2 Paraesthesia of skin
0.027 0.973 0.000
N81.2 Incomplete uterovaginal prolapse
0.027 0.973 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.979 0.021
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.979 0.021
E77 Disorders of glycoprotein metabolism
0.000 0.979 0.020
E76 Disorders of glycosaminoglycan metabolism
0.000 0.979 0.020
E72 Other disorders of amino-acid metabolism
0.000 0.979 0.020
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.979 0.020
E70 Disorders of aromatic amino-acid metabolism
0.000 0.979 0.020
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.979 0.020
E79 Disorders of purine and pyrimidine metabolism
0.000 0.980 0.020
E84 Cystic fibrosis
0.000 0.980 0.019
E74 Other disorders of carbohydrate metabolism
0.000 0.981 0.019
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.981 0.019
E83 Disorders of mineral metabolism
0.000 0.982 0.018
E88 Other metabolic disorders
0.000 0.983 0.017
E73 Lactose intolerance
0.000 0.983 0.017
E89.2 Postprocedural hypoparathyroidism
0.000 0.983 0.017
E83.4 Disorders of magnesium metabolism
0.000 0.984 0.016
E80.6 Other disorders of bilirubin metabolism
0.000 0.984 0.016
E89.3 Postprocedural hypopituitarism
0.000 0.985 0.015
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.985 0.015
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.985 0.015
E89.5 Postprocedural testicular hypofunction
0.000 0.985 0.015
E89.1 Postprocedural hypoinsulinaemia
0.000 0.985 0.015
E86 Volume depletion
0.000 0.985 0.015
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.985 0.015
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.985 0.015
E70.3 Albinism
0.000 0.985 0.015
E70.2 Disorders of tyrosine metabolism
0.000 0.985 0.015
E70.1 Other hyperphenylalaninaemias
0.000 0.985 0.015
E70.0 Classical phenylketonuria
0.000 0.985 0.015
E71.3 Disorders of fatty-acid metabolism
0.000 0.985 0.015
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.985 0.015
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.985 0.015
E71.0 Maple-syrup-urine disease
0.000 0.985 0.015
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.985 0.015
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.985 0.015
E72.5 Disorders of glycine metabolism
0.000 0.985 0.015
E72.4 Disorders of ornithine metabolism
0.000 0.985 0.015
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.985 0.015
E72.2 Disorders of urea cycle metabolism
0.000 0.985 0.015
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.985 0.015
E72.0 Disorders of amino-acid transport
0.000 0.985 0.015
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.985 0.015
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.985 0.015
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.985 0.015
E76.2 Other mucopolysaccharidoses
0.000 0.985 0.015
E76.1 Mucopolysaccharidosis, type II
0.000 0.985 0.015
E76.0 Mucopolysaccharidosis, type I
0.000 0.985 0.015
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.985 0.015
E77.8 Other disorders of glycoprotein metabolism
0.000 0.985 0.015
E77.1 Defects in glycoprotein degradation
0.000 0.985 0.015
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.985 0.015
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.985 0.015
E80.5 Crigler-Najjar syndrome
0.000 0.985 0.015
E80.3 Defects of catalase and peroxydase
0.000 0.985 0.015
E80.2 Other porphyria
0.000 0.985 0.015
E80.1 Porphyria cutanea tarda
0.000 0.985 0.015
E80.0 Hereditary erythropoietic porphyria
0.000 0.985 0.015
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.985 0.015
E89.0 Postprocedural hypothyroidism
0.000 0.985 0.015
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.985 0.014
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.985 0.014
E79.1 Lesch-Nyhan syndrome
0.000 0.985 0.014
E89.4 Postprocedural ovarian failure
0.000 0.985 0.014
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.985 0.014
E84.8 Cystic fibrosis with other manifestations
0.000 0.986 0.014
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.986 0.014
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.986 0.014
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.986 0.014
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.986 0.014
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.986 0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.986 0.014
E74.2 Disorders of galactose metabolism
0.000 0.986 0.014
E74.1 Disorders of fructose metabolism
0.000 0.986 0.014
E74.0 Glycogen storage disease
0.000 0.986 0.014
E75.6 Lipid storage disorder, unspecified
0.000 0.986 0.014
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.986 0.014
E75.3 Sphingolipidosis, unspecified
0.000 0.986 0.014
E75.2 Other sphingolipidosis
0.000 0.986 0.014
E75.1 Other gangliosidosis
0.000 0.986 0.014
E75.0 GM2 gangliosidosis
0.000 0.986 0.014
E80.4 Gilbert's syndrome
0.000 0.986 0.014
Y85.0 Sequelae of motor-vehicle accident
0.000 0.986 0.014
E85 Amyloidosis
0.000 0.986 0.013
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.987 0.013
E83.8 Other disorders of mineral metabolism
0.000 0.987 0.013
E83.2 Disorders of zinc metabolism
0.000 0.987 0.013
E83.0 Disorders of copper metabolism
0.000 0.987 0.013
E84.9 Cystic fibrosis, unspecified
0.000 0.987 0.013
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.987 0.013
E75.5 Other lipid storage disorders
0.000 0.987 0.013
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.987 0.012
E73.8 Other lactose intolerance
0.000 0.987 0.012
E73.1 Secondary lactase deficiency
0.000 0.987 0.012
E73.0 Congenital lactase deficiency
0.000 0.987 0.012
E83.1 Disorders of iron metabolism
0.000 0.988 0.012
E88.2 Lipomatosis, not elsewhere classified
0.000 0.988 0.012
R20 Disturbances of skin sensation
0.012 0.988 0.000
E88.8 Other specified metabolic disorders
0.000 0.989 0.011
H36.0 Diabetic retinopathy
0.000 0.989 0.011
E88.9 Metabolic disorder, unspecified
0.000 0.989 0.011
E83.3 Disorders of phosphorus metabolism
0.000 0.989 0.010
E88.3 Tumour lysis syndrome
0.000 0.990 0.010
E85.8 Other amyloidosis
0.000 0.990 0.010
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.990 0.010
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.990 0.010
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.990 0.010
R20.3 Hyperaesthesia
0.010 0.990 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.990 0.010
E73.9 Lactose intolerance, unspecified
0.000 0.991 0.009
E83.5 Disorders of calcium metabolism
0.000 0.991 0.009
I35.0 Aortic (valve) stenosis
0.009 0.991 0.000
R20.1 Hypoaesthesia of skin
0.008 0.991 0.000
E85.4 Organ-limited amyloidosis
0.000 0.992 0.008
R20.0 Anaesthesia of skin
0.008 0.992 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.992 0.008
M19.97 Arthrosis, unspecified (Ankle and foot)
0.008 0.992 0.000
Z87.8 Personal history of other specified conditions
0.000 0.993 0.007
E78.2 Mixed hyperlipidaemia
0.000 0.993 0.007
R20.8 Other and unspecified disturbances of skin sensation
0.007 0.993 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.993 0.007
E85.9 Amyloidosis, unspecified
0.001 0.993 0.006
E78.4 Other hyperlipidaemia
0.000 0.993 0.007
Y85 Sequelae of transport accidents
0.000 0.993 0.007
E78.6 Lipoprotein deficiency
0.000 0.994 0.006
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.994 0.006
E78.3 Hyperchylomicronaemia
0.000 0.994 0.006
K90.0 Coeliac disease
0.000 0.994 0.006
S70.9 Superficial injury of hip and thigh, unspecified
0.006 0.994 0.000
K91.4 Colostomy and enterostomy malfunction
0.000 0.994 0.006
L40.9 Psoriasis, unspecified
0.000 0.995 0.005
H36 Retinal disorders in diseases classified elsewhere
0.000 0.995 0.005
Y85.9 Sequelae of other and unspecified transport accidents
0.000 0.995 0.005
E66.9 Obesity, unspecified
0.000 0.995 0.005
S52.60 Fracture of lower end of both ulna and radius (closed)
0.000 0.995 0.005
E78.8 Other disorders of lipoprotein metabolism
0.000 0.996 0.004
L40 Psoriasis
0.000 0.996 0.004
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.996 0.004
L40.5 Arthropathic psoriasis
0.000 0.996 0.004
L40.0 Psoriasis vulgaris
0.000 0.996 0.004
L40.8 Other psoriasis
0.000 0.996 0.004
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.996 0.004
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.996 0.004
M35.0 Sicca syndrome [Sjogren]
0.000 0.996 0.004
K14.8 Other diseases of tongue
0.000 0.997 0.003
K12.1 Other forms of stomatitis
0.000 0.997 0.003
I35 Nonrheumatic aortic valve disorders
0.003 0.997 0.000
L40.4 Guttate psoriasis
0.000 0.997 0.003
L40.2 Acrodermatitis continua
0.000 0.997 0.003
Q66 Congenital deformities of feet
0.003 0.997 0.000
Q66.9 Congenital deformity of feet, unspecified
0.003 0.997 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.000 0.997 0.003
Q76 Congenital malformations of spine and bony thorax
0.003 0.997 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.003 0.997 0.000
L29.9 Pruritus, unspecified
0.000 0.997 0.003
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.997 0.003
D06.9 Cervix, unspecified
0.000 0.997 0.003
H52.3 Anisometropia and aniseikonia
0.003 0.997 0.000
I35.1 Aortic (valve) insufficiency
0.003 0.997 0.000
Q65 Congenital deformities of hip
0.003 0.997 0.000
L40.1 Generalised pustular psoriasis
0.000 0.997 0.003
Q50.4 Embryonic cyst of Fallopian tube
0.000 0.997 0.003
Q44.6 Cystic disease of liver
0.003 0.997 0.000
Q65.8 Other congenital deformities of hip
0.003 0.997 0.000
Q76.0 Spina bifida occulta
0.003 0.997 0.000
M35.1 Other overlap syndromes
0.000 0.997 0.003
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.003 0.997 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.997 0.003
M35.7 Hypermobility syndrome
0.000 0.997 0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.003 0.997 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.997 0.003
M35 Other systemic involvement of connective tissue
0.000 0.997 0.003
E87.3 Alkalosis
0.000 0.997 0.003
D12.8 Rectum
0.000 0.997 0.003
M31.3 Wegener's granulomatosis
0.003 0.997 0.000
Q66.2 Metatarsus varus
0.003 0.997 0.000
Q66.0 Talipes equinovarus
0.003 0.997 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.003 0.997 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.003 0.997 0.000
H52 Disorders of refraction and accommodation
0.003 0.997 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.003 0.997 0.000
Q66.3 Other congenital varus deformities of feet
0.003 0.997 0.000
H52.0 Hypermetropia
0.003 0.997 0.000
M31.6 Other giant cell arteritis
0.003 0.997 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.003 0.997 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.003 0.997 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.997 0.003
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.000 0.997 0.003
Q66.6 Other congenital valgus deformities of feet
0.002 0.997 0.000
Q66.5 Congenital pes planus
0.002 0.997 0.000
Q66.4 Talipes calcaneovalgus
0.002 0.997 0.000
Q66.1 Talipes calcaneovarus
0.002 0.997 0.000
K90 Intestinal malabsorption
0.000 0.997 0.003
Q51.2 Other doubling of uterus
0.002 0.997 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.002 0.997 0.000
Q76.8 Other congenital malformations of bony thorax
0.002 0.997 0.000
Q76.7 Congenital malformation of sternum
0.002 0.997 0.000
Q76.6 Other congenital malformations of ribs
0.002 0.997 0.000
Q76.5 Cervical rib
0.002 0.997 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.002 0.997 0.000
Q76.2 Congenital spondylolisthesis
0.002 0.997 0.000
Q76.1 Klippel-Feil syndrome
0.002 0.997 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.002 0.997 0.000
Q75 Other congenital malformations of skull and face bones
0.002 0.997 0.000
Q73 Reduction defects of unspecified limb
0.002 0.997 0.000
Q72 Reduction defects of lower limb
0.002 0.997 0.000
Q71 Reduction defects of upper limb
0.002 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2025 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.