TreeWAS – Variant ID: rs7235528

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T40.2 Other opioids	0.000	0.716	0.284
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.716	0.284
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.718	0.282
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.724	0.276
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.726	0.274
T39.1 4-Aminophenol derivatives	0.000	0.731	0.269
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.740	0.260
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.748	0.252
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.758	0.242
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.762	0.238
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.763	0.237
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.772	0.228
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.776	0.224
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.780	0.220
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.781	0.219
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.790	0.210
T46.1 Calcium-channel blockers	0.000	0.794	0.206
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.796	0.204
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.796	0.204
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.796	0.204
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.796	0.204
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.796	0.204
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.796	0.204
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.798	0.202
T40.8 Lysergide [LSD]	0.000	0.798	0.202
T40.7 Cannabis (derivatives)	0.000	0.798	0.202
T40.5 Cocaine	0.000	0.798	0.202
T40.3 Methadone	0.000	0.798	0.202
T40.1 Heroin	0.000	0.798	0.202
T40.0 Opium	0.000	0.798	0.202
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.798	0.202
T39.4 Antirheumatics, not elsewhere classified	0.000	0.802	0.198
T39.2 Pyrazolone derivatives	0.000	0.802	0.198
T43.9 Psychotropic drug, unspecified	0.000	0.803	0.197
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.803	0.197
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.803	0.197
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.803	0.197
T43.6 Psychostimulants with abuse potential	0.000	0.806	0.193
T40.4 Other synthetic narcotics	0.000	0.808	0.191
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.809	0.191
T36 Poisoning by systemic antibiotics	0.000	0.813	0.187
T42.4 Benzodiazepines	0.000	0.814	0.186
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.814	0.186
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.814	0.186
T46.7 Peripheral vasodilators	0.000	0.814	0.186
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.814	0.186
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.814	0.186
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.814	0.186
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.814	0.186
T42.1 Iminostilbenes	0.000	0.816	0.184
T39.0 Salicylates	0.000	0.821	0.179
T40.6 Other and unspecified narcotics	0.000	0.822	0.178
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.826	0.174
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.826	0.174
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.826	0.174
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.826	0.174
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.826	0.174
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.826	0.174
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.826	0.174
T44.0 Anticholinesterase agents	0.000	0.826	0.174
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.831	0.169
T43.2 Other and unspecified antidepressants	0.000	0.838	0.162
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.838	0.161
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.842	0.157
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.842	0.157
T42.3 Barbiturates	0.000	0.842	0.157
T42.2 Succinimides and oxazolidinediones	0.000	0.842	0.157
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.843	0.157
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.846	0.154
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.854	0.146
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.854	0.146
T37.5 Antiviral drugs	0.000	0.854	0.146
T37.4 Anthelminthics	0.000	0.854	0.146
T37.3 Other antiprotozoal drugs	0.000	0.854	0.146
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.854	0.146
T37.1 Antimycobacterial drugs	0.000	0.854	0.146
T37.0 Sulphonamides	0.000	0.854	0.146
T41.5 Therapeutic gases	0.000	0.854	0.146
T41.4 Anaesthetic, unspecified	0.000	0.854	0.146
T41.3 Local anaesthetics	0.000	0.854	0.146
T41.2 Other and unspecified general anaesthetics	0.000	0.854	0.146
T41.1 Intravenous anaesthetics	0.000	0.854	0.146
T41.0 Inhaled anaesthetics	0.000	0.854	0.146
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.854	0.146
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.854	0.146
T47.7 Emetics	0.000	0.854	0.146
T47.6 Antidiarrhoeal drugs	0.000	0.854	0.146
T47.5 Digestants	0.000	0.854	0.146
T47.4 Other laxatives	0.000	0.854	0.146
T47.3 Saline and osmotic laxatives	0.000	0.854	0.146
T47.2 Stimulant laxatives	0.000	0.854	0.146
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.854	0.146
T47.0 Histamine H(2)-receptor antagonists	0.000	0.854	0.146
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.854	0.146
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.854	0.146
T48.5 Anti-common-cold drugs	0.000	0.854	0.146
T48.4 Expectorants	0.000	0.854	0.146
T48.3 Antitussives	0.000	0.854	0.146
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.854	0.146
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.854	0.146
T48.0 Oxytocic drugs	0.000	0.854	0.146
T49.9 Topical agent, unspecified	0.000	0.854	0.146
T49.8 Other topical agents	0.000	0.854	0.146
T49.7 Dental drugs, topically applied	0.000	0.854	0.146
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.854	0.146
T49.5 Ophthalmological drugs and preparations	0.000	0.854	0.146
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.854	0.146
T49.3 Emollients, demulcents and protectants	0.000	0.854	0.146
T49.2 Local astringents and local detergents	0.000	0.854	0.146
T49.1 Antipruritics	0.000	0.854	0.146
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.854	0.146
T38.9 Other and unspecified hormone antagonists	0.000	0.854	0.146
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.854	0.146
T38.7 Androgens and anabolic congeners	0.000	0.854	0.146
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.854	0.146
T38.5 Other oestrogens and progestogens	0.000	0.854	0.146
T38.4 Oral contraceptives	0.000	0.854	0.146
T38.2 Antithyroid drugs	0.000	0.854	0.146
T38.0 Glucocorticoids and synthetic analogues	0.000	0.854	0.146
T42.0 Hydantoin derivatives	0.000	0.855	0.145
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.856	0.144
T36.9 Systemic antibiotic, unspecified	0.000	0.866	0.134
T36.8 Other systemic antibiotics	0.000	0.866	0.134
T36.7 Antifungal antibiotics, systemically used	0.000	0.866	0.134
T36.6 Rifamycins	0.000	0.866	0.134
T36.5 Aminoglycosides	0.000	0.866	0.134
T36.4 Tetracyclines	0.000	0.866	0.134
T36.3 Macrolides	0.000	0.866	0.134
T36.2 Chloramphenicol group	0.000	0.866	0.134
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.866	0.134
T38.1 Thyroid hormones and substitutes	0.000	0.867	0.132
T50.7 Analeptics and opioid receptor antagonists	0.000	0.879	0.121
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.879	0.121
T50.5 Appetite depressants	0.000	0.879	0.121
T50.4 Drugs affecting uric acid metabolism	0.000	0.879	0.121
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.879	0.121
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.879	0.121
T50.1 Loop [high-ceiling] diuretics	0.000	0.879	0.121
T50.0 Mineralocorticoids and their antagonists	0.000	0.879	0.121
T36.0 Penicillins	0.000	0.882	0.117
T50.8 Diagnostic agents	0.000	0.893	0.107
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.895	0.105
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.897	0.103
T45.8 Other primarily systemic and haematological agents	0.000	0.897	0.103
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.897	0.103
T45.6 Fibrinolysis-affecting drugs	0.000	0.897	0.103
T45.4 Iron and its compounds	0.000	0.897	0.103
T45.3 Enzymes, not elsewhere classified	0.000	0.897	0.103
T45.0 Antiallergic and antiemetic drugs	0.000	0.897	0.102
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.900	0.100
T45.2 Vitamins, not elsewhere classified	0.000	0.902	0.098
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.910	0.090
T45.5 Anticoagulants	0.000	0.922	0.078
D05 Carcinoma in situ of breast	0.036	0.964	0.000
D00-D09 In situ neoplasms	0.035	0.965	0.000
D03 Melanoma in situ	0.035	0.965	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.035	0.965	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.034	0.966	0.000
D05.1 Intraductal carcinoma in situ	0.033	0.967	0.000
D04 Carcinoma in situ of skin	0.032	0.968	0.000
D04.5 Skin of trunk	0.031	0.969	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.031	0.969	0.000
D03.4 Melanoma in situ of scalp and neck	0.030	0.970	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.029	0.971	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.027	0.973	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.027	0.973	0.000
D05.0 Lobular carcinoma in situ	0.026	0.974	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.026	0.974	0.000
D04.1 Skin of eyelid, including canthus	0.026	0.974	0.000
D03.9 Melanoma in situ, unspecified	0.025	0.974	0.000
D03.8 Melanoma in situ of other sites	0.025	0.974	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.025	0.974	0.000
D03.0 Melanoma in situ of lip	0.025	0.974	0.000
D07.5 Prostate	0.025	0.975	0.000
D09 Carcinoma in situ of other and unspecified sites	0.025	0.975	0.000
D07.2 Vagina	0.025	0.975	0.000
D01.0 Colon	0.025	0.975	0.000
D05.7 Other carcinoma in situ of breast	0.024	0.976	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.024	0.976	0.000
D04.4 Skin of scalp and neck	0.024	0.976	0.000
D04.3 Skin of other and unspecified parts of face	0.024	0.976	0.000
D07.4 Penis	0.023	0.976	0.000
D04.9 Skin, unspecified	0.023	0.977	0.000
D04.8 Skin of other sites	0.023	0.977	0.000
D04.0 Skin of lip	0.023	0.977	0.000
D03.5 Melanoma in situ of trunk	0.023	0.977	0.000
D04.2 Skin of ear and external auricular canal	0.022	0.977	0.000
D07.6 Other and unspecified male genital organs	0.022	0.978	0.000
D07.3 Other and unspecified female genital organs	0.022	0.978	0.000
D07.0 Endometrium	0.022	0.978	0.000
D06 Carcinoma in situ of cervix uteri	0.022	0.978	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.021	0.978	0.000
D04.7 Skin of lower limb, including hip	0.021	0.979	0.000
D01.9 Digestive organ, unspecified	0.021	0.979	0.000
D01.7 Other specified digestive organs	0.021	0.979	0.000
D01.5 Liver, gallbladder and bile ducts	0.021	0.979	0.000
D01.4 Other and unspecified parts of intestine	0.021	0.979	0.000
D01.3 Anus and anal canal	0.021	0.979	0.000
D01.2 Rectum	0.021	0.979	0.000
D01.1 Rectosigmoid junction	0.021	0.979	0.000
D07.1 Vulva	0.020	0.980	0.000
R47.1 Dysarthria and anarthria	0.020	0.980	0.000
D00.0 Lip, oral cavity and pharynx	0.019	0.981	0.000
D23.7 Skin of lower limb, including hip	0.000	0.981	0.019
D00.2 Stomach	0.019	0.981	0.000
D00.1 Oesophagus	0.019	0.981	0.000
D09.9 Carcinoma in situ, unspecified	0.018	0.982	0.000
D09.7 Carcinoma in situ of other specified sites	0.018	0.982	0.000
D09.3 Thyroid and other endocrine glands	0.018	0.982	0.000
D09.2 Eye	0.018	0.982	0.000
D09.1 Other and unspecified urinary organs	0.018	0.982	0.000
D09.0 Bladder	0.018	0.982	0.000
D04.6 Skin of upper limb, including shoulder	0.017	0.983	0.000
D06.7 Other parts of cervix	0.016	0.984	0.000
D06.1 Exocervix	0.016	0.984	0.000
D06.0 Endocervix	0.016	0.984	0.000
D02.4 Respiratory system, unspecified	0.016	0.984	0.000
D02.3 Other parts of respiratory system	0.016	0.984	0.000
D02.2 Bronchus and lung	0.016	0.984	0.000
D02.1 Trachea	0.016	0.984	0.000
R47 Speech disturbances, not elsewhere classified	0.014	0.986	0.000
R47.0 Dysphasia and aphasia	0.013	0.987	0.000
D06.9 Cervix, unspecified	0.012	0.988	0.000
D02.0 Larynx	0.011	0.988	0.000
G35 Multiple sclerosis	0.011	0.989	0.000
M50.3 Other cervical disk degeneration	0.000	0.989	0.011
M13.96 Arthritis, unspecified (Lower leg)	0.011	0.989	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.990	0.010
R47.8 Other and unspecified speech disturbances	0.010	0.990	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
H90.5 Sensorineural hearing loss, unspecified	0.009	0.991	0.000
H90.3 Sensorineural hearing loss, bilateral	0.008	0.992	0.000
H90 Conductive and sensorineural hearing loss	0.008	0.992	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.007	0.993	0.000
R47-R49 Symptoms and signs involving speech and voice	0.007	0.993	0.000
N89.5 Stricture and atresia of vagina	0.007	0.993	0.000
G37 Other demyelinating diseases of central nervous system	0.007	0.993	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.007	0.993	0.000
H16 Keratitis	0.007	0.993	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.007	0.993	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.006	0.994	0.000
Z88.5 Personal history of allergy to narcotic agent	0.006	0.994	0.000
H21 Other disorders of iris and ciliary body	0.006	0.994	0.000
M13.93 Arthritis, unspecified (Forearm)	0.006	0.994	0.000
H20 Iridocyclitis	0.006	0.994	0.000
H17 Corneal scars and opacities	0.006	0.994	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
M13.9 Arthritis, unspecified	0.006	0.994	0.000
H90.2 Conductive hearing loss, unspecified	0.006	0.994	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.006	0.994	0.000
H16.0 Corneal ulcer	0.006	0.994	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.006	0.994	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.006	0.994	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.006	0.994	0.000
H20.8 Other iridocyclitis	0.006	0.994	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.006	0.994	0.000
H16.3 Interstitial and deep keratitis	0.006	0.994	0.000
G36 Other acute disseminated demyelination	0.005	0.994	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.994	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.005	0.994	0.000
H90.0 Conductive hearing loss, bilateral	0.005	0.994	0.000
H21.4 Pupillary membranes	0.005	0.995	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.005	0.995	0.000
H17.9 Corneal scar and opacity, unspecified	0.005	0.995	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.995	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.995	0.005
G37.5 Concentric sclerosis [Balo]	0.005	0.995	0.000
G37.4 Subacute necrotising myelitis	0.005	0.995	0.000
G37.2 Central pontine myelinolysis	0.005	0.995	0.000
G37.1 Central demyelination of corpus callosum	0.005	0.995	0.000
G37.0 Diffuse sclerosis	0.005	0.995	0.000
H21.2 Degeneration of iris and ciliary body	0.005	0.995	0.000
H21.0 Hyphaema	0.005	0.995	0.000
H15 Disorders of sclera	0.005	0.995	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.005	0.995	0.000
R48.0 Dyslexia and alexia	0.005	0.995	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.005	0.995	0.000
H16.8 Other keratitis	0.005	0.995	0.000
H16.4 Corneal neovascularisation	0.005	0.995	0.000
H17.8 Other corneal scars and opacities	0.005	0.995	0.000
H16.2 Keratoconjunctivitis	0.005	0.995	0.000
R49 Voice disturbances	0.005	0.995	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.995	0.005
M13.92 Arthritis, unspecified (Upper arm)	0.005	0.995	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.005	0.995	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.005	0.995	0.000
H16.9 Keratitis, unspecified	0.005	0.995	0.000
H20.9 Iridocyclitis, unspecified	0.005	0.995	0.000
H18.8 Other specified disorders of cornea	0.005	0.995	0.000
H18.2 Other corneal oedema	0.005	0.995	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.005	0.995	0.000
H20.0 Acute and subacute iridocyclitis	0.005	0.995	0.000
H17.1 Other central corneal opacity	0.004	0.995	0.000
H17.0 Adherent leukoma	0.004	0.995	0.000
H20.2 Lens-induced iridocyclitis	0.005	0.995	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.005	0.995	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.995	0.005
M24.23 Disorder of ligament (Forearm)	0.005	0.995	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.004	0.995	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.004	0.995	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.004	0.995	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.004	0.995	0.000
R48.2 Apraxia	0.004	0.995	0.000
R48.1 Agnosia	0.004	0.995	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.996	0.004
M24.2 Disorder of ligament	0.004	0.996	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.004	0.996	0.000
H15.8 Other disorders of sclera	0.004	0.996	0.000
C49.9 Connective and soft tissue, unspecified	0.004	0.996	0.000
H20.1 Chronic iridocyclitis	0.004	0.996	0.000
H21.8 Other specified disorders of iris and ciliary body	0.004	0.996	0.000
C49.3 Connective and soft tissue of thorax	0.004	0.996	0.000
G36.9 Acute disseminated demyelination, unspecified	0.004	0.996	0.000
G36.8 Other specified acute disseminated demyelination	0.004	0.996	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.004	0.996	0.000
G36.0 Neuromyelitis optica [Devic]	0.004	0.996	0.000
H15.9 Disorder of sclera, unspecified	0.004	0.996	0.000
H15.0 Scleritis	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
C49.4 Connective and soft tissue of abdomen	0.004	0.996	0.000
R49.8 Other and unspecified voice disturbances	0.004	0.996	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
C49.0 Connective and soft tissue of head, face and neck	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.996	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.004	0.996	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.004	0.996	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
R49.1 Aphonia	0.004	0.996	0.000
R20.2 Paraesthesia of skin	0.000	0.996	0.004
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
R49.2 Hypernasality and hyponasality	0.004	0.996	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.004	0.996	0.000
I08.0 Disorders of both mitral and aortic valves	0.004	0.996	0.000
H15.1 Episcleritis	0.004	0.996	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.996	0.004
Z86.0 Personal history of other neoplasms	0.004	0.996	0.000
C49.5 Connective and soft tissue of pelvis	0.004	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
N80.1 Endometriosis of ovary	0.000	0.996	0.004
M24 Other specific joint derangements	0.004	0.996	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.996	0.004
H90-H95 Other disorders of ear	0.004	0.996	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.996	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.996	0.003
H18.4 Corneal degeneration	0.003	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.003	0.997	0.000
M24.28 Disorder of ligament (Other)	0.003	0.997	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.997	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.997	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.997	0.000
M24.6 Ankylosis of joint	0.003	0.997	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.003	0.997	0.000
M24.5 Contracture of joint	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.003
C49.1 Connective and soft tissue of upper limb, including shoulder	0.003	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.997	0.000
M24.21 Disorder of ligament (Shoulder region)	0.003	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.003	0.997	0.000
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
L50.9 Urticaria, unspecified	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
N89 Other noninflammatory disorders of vagina	0.003	0.997	0.000
H44.2 Degenerative myopia	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
M50 Cervical disk disorders	0.000	0.997	0.003
R49.0 Dysphonia	0.003	0.997	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.997	0.000
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
M24.7 Protrusio acetabuli	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.000	0.997	0.003
H94 Other disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
D75.1 Secondary polycythaemia	0.000	0.997	0.003
M13 Other arthritis	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.003	0.997	0.000
M13.98 Arthritis, unspecified (Other)	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
H91 Other hearing loss	0.003	0.997	0.000
I08 Multiple valve diseases	0.003	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.003	0.997	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.003	0.997	0.000
N89.0 Mild vaginal dysplasia	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.003	0.997	0.000
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.997	0.003
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
M10.90 Gout, unspecified (Multiple sites)	0.003	0.997	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.997	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.003	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
M24.0 Loose body in joint	0.002	0.997	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.997	0.000
M50.9 Cervical disk disorder, unspecified	0.000	0.997	0.002
H44 Disorders of globe	0.003	0.997	0.000
H92 Otalgia and effusion of ear	0.002	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.997	0.000
N89.7 Haematocolpos	0.002	0.997	0.000
N89.4 Leukoplakia of vagina	0.002	0.997	0.000
N89.3 Dysplasia of vagina, unspecified	0.002	0.997	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.002	0.997	0.000
N89.1 Moderate vaginal dysplasia	0.002	0.997	0.000
F17.2 Dependence syndrome	0.003	0.997	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
M50.8 Other cervical disk disorders	0.000	0.998	0.002
L50 Urticaria	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
M47.8 Other spondylosis	0.000	0.998	0.002
H91.8 Other specified hearing loss	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.000	0.998	0.002
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
L50.8 Other urticaria	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M13.1 Monoarthritis, not elsewhere classified	0.002	0.998	0.000
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.998	0.002
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations