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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7237497
log Bayes Factor = 11.9138
Chromosome 18   position 12,777,325  (GRCh37) Explore rs7237497 on Ensembl!
Variant rs7237497 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.013 0.987
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.014 0.986
E10.3 With ophthalmic complications
0.000 0.019 0.981
E11.3 With ophthalmic complications
0.000 0.023 0.977
E27 Other disorders of adrenal gland
0.000 0.046 0.954
E21.0 Primary hyperparathyroidism
0.000 0.046 0.954
E10.1 With ketoacidosis
0.000 0.053 0.947
D50.9 Iron deficiency anaemia, unspecified
0.000 0.082 0.918
D50 Iron deficiency anaemia
0.000 0.091 0.909
E11.1 With ketoacidosis
0.000 0.095 0.905
E21.3 Hyperparathyroidism, unspecified
0.000 0.110 0.890
K50 Crohn's disease [regional enteritis]
0.000 0.113 0.887
K50.9 Crohn's disease, unspecified
0.000 0.116 0.884
E24 Cushing's syndrome
0.000 0.123 0.877
E27.9 Disorder of adrenal gland, unspecified
0.000 0.124 0.876
D50-D53 Nutritional anaemias
0.000 0.126 0.874
D51 Vitamin B12 deficiency anaemia
0.000 0.130 0.870
K50.0 Crohn's disease of small intestine
0.000 0.130 0.870
D50.8 Other iron deficiency anaemias
0.000 0.133 0.867
E10.4 With neurological complications
0.000 0.140 0.860
E10.6 With other specified complications
0.000 0.141 0.859
E23 Hypofunction and other disorders of pituitary gland
0.000 0.145 0.855
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.151 0.849
E29 Testicular dysfunction
0.000 0.152 0.848
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.157 0.842
K50.1 Crohn's disease of large intestine
0.000 0.163 0.837
E03.1 Congenital hypothyroidism without goitre
0.000 0.170 0.830
E27.8 Other specified disorders of adrenal gland
0.000 0.190 0.810
E22 Hyperfunction of pituitary gland
0.000 0.195 0.805
E34 Other endocrine disorders
0.000 0.196 0.804
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.198 0.802
E21.4 Other specified disorders of parathyroid gland
0.000 0.202 0.798
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.202 0.798
E11.6 With other specified complications
0.000 0.212 0.788
K50.8 Other Crohn's disease
0.000 0.215 0.785
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.224 0.776
E10.8 With unspecified complications
0.000 0.240 0.760
E32 Diseases of thymus
0.000 0.244 0.756
E11.2 With renal complications
0.000 0.250 0.750
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.250 0.750
E14 Unspecified diabetes mellitus
0.000 0.265 0.734
E50-E64 Other nutritional deficiencies
0.000 0.268 0.732
E25 Adrenogenital disorders
0.000 0.269 0.731
E23.6 Other disorders of pituitary gland
0.000 0.270 0.730
E24.9 Cushing's syndrome, unspecified
0.000 0.274 0.726
E31 Polyglandular dysfunction
0.000 0.276 0.724
K50-K52 Noninfective enteritis and colitis
0.000 0.280 0.720
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.282 0.718
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.285 0.715
E40-E46 Malnutrition
0.000 0.285 0.715
E29.1 Testicular hypofunction
0.000 0.290 0.710
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.291 0.709
K51 Ulcerative colitis
0.000 0.304 0.696
E07 Other disorders of thyroid
0.000 0.304 0.696
E11.7 With multiple complications
0.000 0.306 0.694
E11.5 With peripheral circulatory complications
0.000 0.310 0.690
E24.0 Pituitary-dependent Cushing's disease
0.000 0.311 0.689
E10.7 With multiple complications
0.000 0.312 0.687
E27.5 Adrenomedullary hyperfunction
0.000 0.316 0.684
E27.0 Other adrenocortical overactivity
0.000 0.316 0.684
E10.0 With coma
0.000 0.323 0.677
E11.8 With unspecified complications
0.000 0.324 0.675
E53 Deficiency of other B group vitamins
0.000 0.329 0.670
E24.2 Drug-induced Cushing's syndrome
0.000 0.330 0.670
E11.0 With coma
0.000 0.330 0.670
E26 Hyperaldosteronism
0.000 0.332 0.668
K90.0 Coeliac disease
0.000 0.332 0.668
E29.9 Testicular dysfunction, unspecified
0.000 0.341 0.659
E23.7 Disorder of pituitary gland, unspecified
0.000 0.341 0.659
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.343 0.657
E34.8 Other specified endocrine disorders
0.000 0.344 0.656
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.345 0.655
K51.4 Pseudopolyposis of colon
0.000 0.346 0.654
E27.1 Primary adrenocortical insufficiency
0.000 0.346 0.654
K51.9 Ulcerative colitis, unspecified
0.000 0.346 0.654
E23.0 Hypopituitarism
0.000 0.347 0.653
E22.1 Hyperprolactinaemia
0.000 0.348 0.652
E24.8 Other Cushing's syndrome
0.000 0.351 0.649
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.353 0.647
D50.1 Sideropenic dysphagia
0.000 0.355 0.645
E20 Hypoparathyroidism
0.000 0.360 0.640
E34.0 Carcinoid syndrome
0.000 0.362 0.638
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.366 0.634
E14.9 Without complications
0.000 0.368 0.632
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.371 0.629
E24.3 Ectopic ACTH syndrome
0.000 0.371 0.629
E24.1 Nelson's syndrome
0.000 0.371 0.629
E53.8 Deficiency of other specified B group vitamins
0.000 0.373 0.627
D51.2 Transcobalamin II deficiency
0.000 0.376 0.624
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.376 0.624
E06 Thyroiditis
0.000 0.377 0.623
E03.8 Other specified hypothyroidism
0.000 0.378 0.622
E23.1 Drug-induced hypopituitarism
0.000 0.387 0.613
E14.1 With ketoacidosis
0.000 0.390 0.610
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.390 0.610
E29.8 Other testicular dysfunction
0.000 0.392 0.608
E29.0 Testicular hyperfunction
0.000 0.392 0.608
E21.2 Other hyperparathyroidism
0.000 0.393 0.607
E10.5 With peripheral circulatory complications
0.000 0.394 0.606
E13.9 Without complications
0.000 0.397 0.603
E05.9 Thyrotoxicosis, unspecified
0.000 0.398 0.602
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.400 0.600
E14.4 With neurological complications
0.000 0.405 0.595
E27.2 Addisonian crisis
0.000 0.410 0.590
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.410 0.590
D52 Folate deficiency anaemia
0.000 0.411 0.589
E32.8 Other diseases of thymus
0.000 0.419 0.581
E22.8 Other hyperfunction of pituitary gland
0.000 0.423 0.577
E34.5 Androgen resistance syndrome
0.000 0.423 0.576
E34.4 Constitutional tall stature
0.000 0.423 0.576
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.423 0.576
E34.1 Other hypersecretion of intestinal hormones
0.000 0.423 0.576
E13.3 With ophthalmic complications
0.000 0.429 0.571
E34.3 Short stature, not elsewhere classified
0.000 0.429 0.571
E16 Other disorders of pancreatic internal secretion
0.000 0.429 0.571
D53 Other nutritional anaemias
0.000 0.438 0.561
E10.2 With renal complications
0.000 0.439 0.561
E05.8 Other thyrotoxicosis
0.000 0.441 0.559
E13.8 With unspecified complications
0.000 0.444 0.556
E13.7 With multiple complications
0.000 0.444 0.556
E13.6 With other specified complications
0.000 0.444 0.556
E13.5 With peripheral circulatory complications
0.000 0.444 0.556
E13.4 With neurological complications
0.000 0.444 0.556
E13.2 With renal complications
0.000 0.444 0.556
E13.1 With ketoacidosis
0.000 0.444 0.556
E13.0 With coma
0.000 0.444 0.556
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.452 0.548
E32.9 Disease of thymus, unspecified
0.000 0.458 0.542
E32.1 Abscess of thymus
0.000 0.458 0.542
E32.0 Persistent hyperplasia of thymus
0.000 0.458 0.542
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.461 0.538
K51.5 Mucosal proctocolitis
0.000 0.461 0.539
E58 Dietary calcium deficiency
0.000 0.462 0.538
E15 Nondiabetic hypoglycaemic coma
0.000 0.462 0.538
E28 Ovarian dysfunction
0.000 0.466 0.534
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.469 0.531
E07.9 Disorder of thyroid, unspecified
0.000 0.471 0.529
E14.7 With multiple complications
0.000 0.473 0.527
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.474 0.526
E31.0 Autoimmune polyglandular failure
0.000 0.474 0.526
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.475 0.525
E50 Vitamin A deficiency
0.000 0.475 0.525
E60 Dietary zinc deficiency
0.000 0.475 0.525
E59 Dietary selenium deficiency
0.000 0.475 0.525
E52 Niacin deficiency [pellagra]
0.000 0.475 0.525
E25.9 Adrenogenital disorder, unspecified
0.000 0.476 0.524
E25.8 Other adrenogenital disorders
0.000 0.476 0.524
E31.9 Polyglandular dysfunction, unspecified
0.000 0.481 0.519
E31.8 Other polyglandular dysfunction
0.000 0.481 0.519
E31.1 Polyglandular hyperfunction
0.000 0.481 0.519
E34.9 Endocrine disorder, unspecified
0.000 0.485 0.515
E56 Other vitamin deficiencies
0.000 0.485 0.515
E14.0 With coma
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.487 0.512
E45 Retarded development following protein-energy malnutrition
0.000 0.487 0.512
E43 Unspecified severe protein-energy malnutrition
0.000 0.487 0.512
E42 Marasmic kwashiorkor
0.000 0.487 0.512
E41 Nutritional marasmus
0.000 0.487 0.512
E40 Kwashiorkor
0.000 0.487 0.512
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.488 0.512
E46 Unspecified protein-energy malnutrition
0.000 0.490 0.510
E05.5 Thyroid crisis or storm
0.000 0.491 0.508
E05.4 Thyrotoxicosis factitia
0.000 0.491 0.508
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.491 0.508
E14.8 With unspecified complications
0.000 0.492 0.507
E14.6 With other specified complications
0.000 0.493 0.507
E63 Other nutritional deficiencies
0.000 0.498 0.501
E07.1 Dyshormogenetic goitre
0.000 0.501 0.499
E07.0 Hypersecretion of calcitonin
0.000 0.501 0.499
E11.4 With neurological complications
0.000 0.502 0.498
E54 Ascorbic acid deficiency
0.000 0.502 0.498
E06.3 Autoimmune thyroiditis
0.000 0.508 0.492
E23.2 Diabetes insipidus
0.000 0.511 0.489
E53.1 Pyridoxine deficiency
0.000 0.519 0.481
E53.0 Riboflavin deficiency
0.000 0.519 0.481
E53.9 Vitamin B deficiency, unspecified
0.000 0.519 0.480
E26.8 Other hyperaldosteronism
0.000 0.521 0.479
E26.1 Secondary hyperaldosteronism
0.000 0.521 0.479
E26.9 Hyperaldosteronism, unspecified
0.000 0.525 0.475
E14.5 With peripheral circulatory complications
0.000 0.527 0.473
K90 Intestinal malabsorption
0.000 0.528 0.472
E51 Thiamine deficiency
0.000 0.529 0.471
E14.2 Withrenal complications
0.000 0.535 0.465
E20.0 Idiopathic hypoparathyroidism
0.000 0.541 0.459
E20.1 Pseudohypoparathyroidism
0.000 0.544 0.456
E22.0 Acromegaly and pituitary gigantism
0.000 0.545 0.454
K51.8 Other ulcerative colitis
0.000 0.547 0.453
E55 Vitamin D deficiency
0.000 0.548 0.452
E06.4 Drug-induced thyroiditis
0.000 0.553 0.446
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.553 0.446
E06.0 Acute thyroiditis
0.000 0.553 0.446
E07.8 Other specified disorders of thyroid
0.000 0.562 0.438
E20.8 Other hypoparathyroidism
0.000 0.563 0.437
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.564 0.436
E16.2 Hypoglycaemia, unspecified
0.000 0.564 0.436
E26.0 Primary hyperaldosteronism
0.000 0.565 0.435
E61 Deficiency of other nutrient elements
0.000 0.573 0.427
D52.8 Other folate deficiency anaemias
0.000 0.578 0.422
D52.1 Drug-induced folate deficiency anaemia
0.000 0.578 0.422
D52.0 Dietary folate deficiency anaemia
0.000 0.578 0.422
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.579 0.421
E06.1 Subacute thyroiditis
0.000 0.583 0.416
E20.9 Hypoparathyroidism, unspecified
0.000 0.585 0.415
E11.9 Without complications
0.000 0.590 0.410
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.590 0.409
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.590 0.409
E16.4 Abnormal secretion of gastrin
0.000 0.590 0.409
E16.3 Increased secretion of glucagon
0.000 0.590 0.409
E16.1 Other hypoglycaemia
0.000 0.594 0.406
E06.5 Other chronic thyroiditis
0.000 0.596 0.403
D53.8 Other specified nutritional anaemias
0.000 0.597 0.403
D53.2 Scorbutic anaemia
0.000 0.597 0.403
D53.0 Protein deficiency anaemia
0.000 0.597 0.403
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.604 0.396
K51.2 Ulcerative (chronic) proctitis
0.000 0.607 0.393
D52.9 Folate deficiency anaemia, unspecified
0.000 0.616 0.384
E28.9 Ovarian dysfunction, unspecified
0.000 0.617 0.383
E28.8 Other ovarian dysfunction
0.000 0.617 0.383
E28.1 Androgen excess
0.000 0.617 0.383
E28.0 Oestrogen excess
0.000 0.617 0.383
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.618 0.382
E50.9 Vitamin A deficiency, unspecified
0.000 0.623 0.376
E50.8 Other manifestations of vitamin A deficiency
0.000 0.623 0.376
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.623 0.376
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.623 0.376
E50.5 Vitamin A deficiency with night blindness
0.000 0.623 0.376
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.623 0.376
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.623 0.376
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.623 0.376
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.623 0.376
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.623 0.376
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.623 0.376
E64.8 Sequelae of other nutritional deficiencies
0.000 0.623 0.376
E64.3 Sequelae of rickets
0.000 0.623 0.376
E64.2 Sequelae of vitamin C deficiency
0.000 0.623 0.376
E64.1 Sequelae of vitamin A deficiency
0.000 0.623 0.376
E64.0 Sequelae of protein-energy malnutrition
0.000 0.623 0.376
E06.9 Thyroiditis, unspecified
0.000 0.626 0.373
E56.9 Vitamin deficiency, unspecified
0.000 0.631 0.369
E56.8 Deficiency of other vitamins
0.000 0.631 0.369
E56.0 Deficiency of vitamin E
0.000 0.631 0.369
K90.8 Other intestinal malabsorption
0.000 0.631 0.368
E44.1 Mild protein-energy malnutrition
0.000 0.632 0.367
E44.0 Moderate protein-energy malnutrition
0.000 0.632 0.367
E63.8 Other specified nutritional deficiencies
0.000 0.640 0.360
E63.1 Imbalance of constituents of food intake
0.000 0.640 0.360
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.640 0.360
E56.1 Deficiency of vitamin K
0.000 0.641 0.359
K90.9 Intestinal malabsorption, unspecified
0.000 0.647 0.353
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.656 0.344
K90.3 Pancreatic steatorrhoea
0.000 0.661 0.338
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.661 0.338
K90.1 Tropical sprue
0.000 0.661 0.338
E51.9 Thiamine deficiency, unspecified
0.000 0.662 0.338
E51.8 Other manifestations of thiamine deficiency
0.000 0.662 0.338
E51.1 Beriberi
0.000 0.662 0.338
E63.9 Nutritional deficiency, unspecified
0.000 0.664 0.336
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.666 0.334
E55.0 Rickets, active
0.000 0.676 0.324
E65-E68 Obesity and other hyperalimentation
0.000 0.681 0.319
E28.3 Primary ovarian failure
0.000 0.684 0.315
E61.9 Deficiency of nutrient element, unspecified
0.000 0.694 0.306
E61.8 Deficiency of other specified nutrient elements
0.000 0.694 0.306
E61.7 Deficiency of multiple nutrient elements
0.000 0.694 0.306
E61.6 Vanadium deficiency
0.000 0.694 0.306
E61.5 Molybdenum deficiency
0.000 0.694 0.306
E61.4 Chromium deficiency
0.000 0.694 0.306
E61.3 Manganese deficiency
0.000 0.694 0.306
E61.0 Copper deficiency
0.000 0.694 0.306
K52 Other non-infective gastro-enteritis and colitis
0.000 0.697 0.303
E28.2 Polycystic ovarian syndrome
0.000 0.698 0.302
E61.2 Magnesium deficiency
0.000 0.710 0.290
E51.2 Wernicke's encephalopathy
0.000 0.716 0.283
D53.9 Nutritional anaemia, unspecified
0.001 0.722 0.277
E70-E90 Metabolic disorders
0.000 0.730 0.270
E14.3 With ophthalmic complications
0.000 0.731 0.268
E04 Other non-toxic goitre
0.000 0.734 0.266
K90-K93 Other diseases of the digestive system
0.000 0.739 0.261
E55.9 Vitamin D deficiency, unspecified
0.000 0.749 0.250
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.750 0.250
E89.0 Postprocedural hypothyroidism
0.000 0.758 0.242
E83 Disorders of mineral metabolism
0.000 0.759 0.241
Chapter XI Diseases of the digestive system
0.000 0.762 0.238
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.766 0.234
E61.1 Iron deficiency
0.000 0.766 0.233
E83.1 Disorders of iron metabolism
0.000 0.767 0.233
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.000 0.767 0.233
E85 Amyloidosis
0.000 0.769 0.231
K07 Dentofacial anomalies [including malocclusion]
0.000 0.770 0.230
E67 Other hyperalimentation
0.000 0.771 0.229
E68 Sequelae of hyperalimentation
0.000 0.771 0.229
K11 Diseases of salivary glands
0.000 0.772 0.228
K07.3 Anomalies of tooth position
0.000 0.773 0.227
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.782 0.218
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.788 0.212
E04.0 Non-toxic diffuse goitre
0.000 0.789 0.211
K11.2 Sialoadenitis
0.000 0.793 0.207
K11.5 Sialolithiasis
0.000 0.796 0.204
E84 Cystic fibrosis
0.000 0.797 0.203
K12 Stomatitis and related lesions
0.000 0.799 0.201
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.799 0.201
K09 Cysts of oral region, not elsewhere classified
0.000 0.799 0.201
E70 Disorders of aromatic amino-acid metabolism
0.000 0.801 0.199
E74 Other disorders of carbohydrate metabolism
0.000 0.802 0.198
E89.5 Postprocedural testicular hypofunction
0.000 0.804 0.196
E89.1 Postprocedural hypoinsulinaemia
0.000 0.804 0.196
E76 Disorders of glycosaminoglycan metabolism
0.000 0.806 0.193
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.806 0.193
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.806 0.193
K11.9 Disease of salivary gland, unspecified
0.000 0.807 0.193
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.808 0.192
E85.9 Amyloidosis, unspecified
0.000 0.808 0.191
E04.8 Other specified non-toxic goitre
0.000 0.809 0.191
K52.3 Indeterminate colitis
0.000 0.810 0.190
E79 Disorders of purine and pyrimidine metabolism
0.000 0.811 0.189
E77 Disorders of glycoprotein metabolism
0.000 0.812 0.188
K11.1 Hypertrophy of salivary gland
0.000 0.813 0.187
K12.1 Other forms of stomatitis
0.000 0.813 0.187
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.813 0.187
K07.4 Malocclusion, unspecified
0.000 0.815 0.185
E83.4 Disorders of magnesium metabolism
0.000 0.816 0.184
K07.1 Anomalies of jaw-cranial base relationship
0.000 0.817 0.183
E85.8 Other amyloidosis
0.000 0.819 0.181
K09.0 Developmental odontogenic cysts
0.000 0.819 0.181
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.821 0.179
E89.2 Postprocedural hypoparathyroidism
0.000 0.821 0.178
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.822 0.178
E85.3 Secondary systemic amyloidosis
0.000 0.823 0.177
K04 Diseases of pulp and periapical tissues
0.000 0.823 0.177
K11.3 Abscess of salivary gland
0.000 0.823 0.176
K07.9 Dentofacial anomaly, unspecified
0.000 0.824 0.176
K07.0 Major anomalies of jaw size
0.000 0.824 0.176
K03 Other diseases of hard tissues of teeth
0.000 0.825 0.175
K00 Disorders of tooth development and eruption
0.000 0.825 0.175
E72 Other disorders of amino-acid metabolism
0.000 0.827 0.173
E83.8 Other disorders of mineral metabolism
0.000 0.827 0.173
E83.2 Disorders of zinc metabolism
0.000 0.827 0.173
E83.0 Disorders of copper metabolism
0.000 0.827 0.173
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.827 0.173
E73 Lactose intolerance
0.000 0.829 0.171
K11.0 Atrophy of salivary gland
0.000 0.833 0.167
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.834 0.166
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.834 0.166
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.834 0.166
K07.5 Dentofacial functional abnormalities
0.000 0.834 0.166
K04.8 Radicular cyst
0.000 0.834 0.166
E67.8 Other specified hyperalimentation
0.000 0.836 0.164
E67.3 Hypervitaminosis D
0.000 0.836 0.164
E67.2 Megavitamin-B6 syndrome
0.000 0.836 0.164
E67.1 Hypercarotenaemia
0.000 0.836 0.164
E67.0 Hypervitaminosis A
0.000 0.836 0.164
K11.4 Fistula of salivary gland
0.000 0.836 0.164
K07.6 Temporomandibular joint disorders
0.000 0.838 0.162
K06 Other disorders of gingiva and edentulous alveolar ridge
0.000 0.839 0.161
E85.4 Organ-limited amyloidosis
0.000 0.839 0.161
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.839 0.160
K12.0 Recurrent oral aphthae
0.000 0.841 0.159
K09.8 Other cysts of oral region, not elsewhere classified
0.000 0.842 0.158
E89.4 Postprocedural ovarian failure
0.000 0.846 0.153
K11.7 Disturbances of salivary secretion
0.000 0.847 0.153
K07.8 Other dentofacial anomalies
0.000 0.847 0.152
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.848 0.152
E84.9 Cystic fibrosis, unspecified
0.000 0.848 0.152
E89.3 Postprocedural hypopituitarism
0.000 0.849 0.151
K11.8 Other diseases of salivary glands
0.000 0.849 0.151
E65 Localised adiposity
0.001 0.849 0.150
E75.2 Other sphingolipidosis
0.000 0.851 0.149
E70.3 Albinism
0.000 0.851 0.148
K14 Diseases of tongue
0.000 0.852 0.148
E75.5 Other lipid storage disorders
0.000 0.852 0.148
K04.4 Acute apical periodontitis of pulpal origin
0.000 0.852 0.148
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.852 0.148
K00.0 Anodontia
0.000 0.853 0.147
K10 Other diseases of jaws
0.000 0.854 0.146
E84.8 Cystic fibrosis with other manifestations
0.000 0.854 0.145
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.854 0.145
E83.5 Disorders of calcium metabolism
0.000 0.855 0.145
E75.6 Lipid storage disorder, unspecified
0.000 0.855 0.144
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.855 0.144
E75.3 Sphingolipidosis, unspecified
0.000 0.855 0.144
E75.1 Other gangliosidosis
0.000 0.855 0.144
E75.0 GM2 gangliosidosis
0.000 0.855 0.144
K09.9 Cyst of oral region, unspecified
0.000 0.856 0.144
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.000 0.856 0.144
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.857 0.143
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.857 0.143
E70.2 Disorders of tyrosine metabolism
0.000 0.857 0.143
E70.1 Other hyperphenylalaninaemias
0.000 0.857 0.143
E70.0 Classical phenylketonuria
0.000 0.857 0.143
K07.2 Anomalies of dental arch relationship
0.000 0.857 0.142
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.858 0.142
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.858 0.142
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.858 0.142
E74.2 Disorders of galactose metabolism
0.000 0.858 0.142
E74.1 Disorders of fructose metabolism
0.000 0.858 0.142
K04.5 Chronic apical periodontitis
0.000 0.858 0.142
E71.3 Disorders of fatty-acid metabolism
0.000 0.861 0.139
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.861 0.139
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.861 0.139
E71.0 Maple-syrup-urine disease
0.000 0.861 0.139
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.861 0.139
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.861 0.139
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.861 0.139
E76.2 Other mucopolysaccharidoses
0.000 0.861 0.139
E76.1 Mucopolysaccharidosis, type II
0.000 0.861 0.139
E76.0 Mucopolysaccharidosis, type I
0.000 0.861 0.139
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.861 0.139
K03.8 Other specified diseases of hard tissues of teeth
0.000 0.864 0.136
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.864 0.135
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.864 0.135
E79.1 Lesch-Nyhan syndrome
0.000 0.864 0.135
K09.1 Developmental (nonodontogenic) cysts of oral region
0.000 0.864 0.135
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.865 0.135
E77.1 Defects in glycoprotein degradation
0.000 0.865 0.135
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.865 0.135
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.866 0.134
K93.1 Megacolon in Chagas' disease
0.000 0.866 0.134
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.866 0.134
K03.9 Disease of hard tissues of teeth, unspecified
0.000 0.867 0.133
K11.6 Mucocele of salivary gland
0.000 0.867 0.133
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.869 0.131
E77.8 Other disorders of glycoprotein metabolism
0.000 0.871 0.129
K12.3 Oral mucositis (ulcerative)
0.000 0.871 0.129
K00.1 Supernumerary teeth
0.000 0.873 0.127
K09.2 Other cysts of jaw
0.000 0.873 0.127
K04.3 Abnormal hard tissue formation in pulp
0.000 0.873 0.127
K04.2 Pulp degeneration
0.000 0.873 0.127
K04.1 Necrosis of pulp
0.000 0.873 0.127
K01 Embedded and impacted teeth
0.000 0.873 0.127
K03.7 Posteruptive colour changes of dental hard tissues
0.000 0.874 0.126
K03.5 Ankylosis of teeth
0.000 0.874 0.126
K03.4 Hypercementosis
0.000 0.874 0.126
K03.2 Erosion of teeth
0.000 0.874 0.126
K03.1 Abrasion of teeth
0.000 0.874 0.126
K03.0 Excessive attrition of teeth
0.000 0.874 0.126
K00.7 Teething syndrome
0.000 0.874 0.125
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified
0.000 0.874 0.125
K00.4 Disturbances in tooth formation
0.000 0.874 0.125
K00.3 Mottled teeth
0.000 0.874 0.125
K00.2 Abnormalities of size and form of teeth
0.000 0.874 0.125
K05 Gingivitis and periodontal diseases
0.000 0.875 0.125
K00.8 Other disorders of tooth development
0.000 0.875 0.124
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.876 0.124
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.876 0.124
E72.5 Disorders of glycine metabolism
0.000 0.876 0.124
E72.4 Disorders of ornithine metabolism
0.000 0.876 0.124
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.876 0.124
E72.2 Disorders of urea cycle metabolism
0.000 0.876 0.124
E73.8 Other lactose intolerance
0.000 0.877 0.123
E73.1 Secondary lactase deficiency
0.000 0.877 0.123
E73.0 Congenital lactase deficiency
0.000 0.877 0.123
E74.0 Glycogen storage disease
0.000 0.877 0.123
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.878 0.122
E04.2 Non-toxic multinodular goitre
0.000 0.879 0.121
K00.9 Disorder of tooth development, unspecified
0.000 0.879 0.121
E87.3 Alkalosis
0.000 0.879 0.121
E04.9 Non-toxic goitre, unspecified
0.000 0.879 0.120
K03.3 Pathological resorption of teeth
0.000 0.880 0.120

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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