TreeWAS – Variant ID: rs72700121

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z92.1 Personal history of long-term (current) use of anticoagulants	1.000	0.000	0.000
D68.2 Hereditary deficiency of other clotting factors	0.566	0.434	0.000
D68 Other coagulation defects	0.520	0.480	0.000
D68.9 Coagulation defect, unspecified	0.486	0.514	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.430	0.570	0.000
D68.5 Primary Thrombophilia	0.417	0.583	0.000
D68.8 Other specified coagulation defects	0.411	0.589	0.000
D68.0 Von Willebrand's disease	0.395	0.605	0.000
D68.4 Acquired coagulation factor deficiency	0.373	0.627	0.000
D68.1 Hereditary factor XI deficiency	0.373	0.627	0.000
D68.6 Other Thrombophilia	0.334	0.666	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.104	0.896	0.000
D67 Hereditary factor IX deficiency	0.075	0.925	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.069	0.931	0.000
D66 Hereditary factor VIII deficiency	0.068	0.932	0.000
D69 Purpura and other haemorrhagic conditions	0.037	0.962	0.000
H53.8 Other visual disturbances	0.000	0.969	0.031
D69.0 Allergic purpura	0.029	0.971	0.000
D69.2 Other nonthrombocytopenic purpura	0.029	0.971	0.000
D69.9 Haemorrhagic condition, unspecified	0.029	0.971	0.000
D69.8 Other specified haemorrhagic conditions	0.027	0.973	0.000
D69.1 Qualitative platelet defects	0.027	0.973	0.000
H53 Visual disturbances	0.000	0.973	0.027
H53.1 Subjective visual disturbances	0.000	0.974	0.026
D69.5 Secondary thrombocytopenia	0.026	0.974	0.000
D69.4 Other primary thrombocytopenia	0.025	0.975	0.000
H53.9 Visual disturbance, unspecified	0.000	0.977	0.023
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.979	0.021
H53.0 Amblyopia ex anopsia	0.000	0.980	0.020
H53.4 Visual field defects	0.000	0.980	0.020
H53.6 Night blindness	0.000	0.981	0.019
H53.5 Colour vision deficiencies	0.000	0.981	0.019
H53.3 Other disorders of binocular vision	0.000	0.981	0.019
D69.3 Idiopathic thrombocytopenic purpura	0.016	0.984	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.015	0.985	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.986	0.014
D55-D59 Haemolytic anaemias	0.014	0.986	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.987	0.013
D59 Acquired haemolytic anaemia	0.012	0.988	0.000
D80-D89 Certain disorders involving the immune mechanism	0.011	0.989	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.011	0.989	0.000
D58 Other hereditary haemolytic anaemias	0.011	0.989	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.011	0.989	0.000
D59.1 Other autoimmune haemolytic anaemias	0.010	0.989	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.010	0.990	0.000
S82.86 Maisonneuve's fracture	0.000	0.990	0.010
D57 Sickle-cell disorders	0.010	0.990	0.000
D56 Thalassaemia	0.010	0.990	0.000
D55 Anaemia due to enzyme disorders	0.010	0.990	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.010	0.990	0.000
D72 Other disorders of white blood cells	0.009	0.990	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.009	0.991	0.000
D72.1 Eosinophilia	0.009	0.991	0.000
D58.0 Hereditary spherocytosis	0.009	0.991	0.000
D59.8 Other acquired haemolytic anaemias	0.009	0.991	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.009	0.991	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.009	0.991	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.009	0.991	0.000
D59.3 Haemolytic-uraemic syndrome	0.009	0.991	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.009	0.991	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.009	0.991	0.000
S64.4 Injury of digital nerve of other finger	0.009	0.991	0.000
D84 Other immunodeficiencies	0.008	0.991	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.008	0.991	0.000
D83 Common variable immunodeficiency	0.008	0.991	0.000
D82 Immunodeficiency associated with other major defects	0.008	0.991	0.000
D81 Combined immunodeficiencies	0.008	0.991	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.008	0.992	0.000
D89.3 Immune reconstitution syndrome	0.008	0.992	0.000
D89.1 Cryoglobulinaemia	0.008	0.992	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.008	0.992	0.000
M79.60 Pain in limb (Multiple sites)	0.008	0.992	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.008	0.992	0.000
D58.2 Other haemoglobinopathies	0.008	0.992	0.000
D58.1 Hereditary elliptocytosis	0.008	0.992	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.992	0.008
H53-H54 Visual disturbances and blindness	0.000	0.992	0.008
D73 Diseases of spleen	0.008	0.992	0.000
D74 Methaemoglobinaemia	0.007	0.992	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.007	0.992	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.007	0.992	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.008	0.992	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.007	0.992	0.000
D55.8 Other anaemias due to enzyme disorders	0.007	0.992	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.007	0.992	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.007	0.992	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.007	0.992	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.007	0.992	0.000
D56.9 Thalassaemia, unspecified	0.007	0.992	0.000
D56.8 Other thalassaemias	0.007	0.992	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.007	0.992	0.000
D56.3 Thalassaemia trait	0.007	0.992	0.000
D56.2 Delta-beta thalassaemia	0.007	0.992	0.000
D56.1 Beta thalassaemia	0.007	0.992	0.000
D56.0 Alpha thalassaemia	0.007	0.992	0.000
D57.8 Other sickle-cell disorders	0.007	0.992	0.000
D57.3 Sickle-cell trait	0.007	0.992	0.000
D57.2 Double heterozygous sickling disorders	0.007	0.992	0.000
D57.1 Sickle-cell anaemia without crisis	0.007	0.992	0.000
D57.0 Sickle-cell anaemia with crisis	0.007	0.992	0.000
D75 Other diseases of blood and blood-forming organs	0.007	0.993	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.007	0.993	0.000
N39.4 Other specified urinary incontinence	0.007	0.993	0.000
D72.9 Disorder of white blood cells, unspecified	0.007	0.993	0.000
D72.0 Genetic anomalies of leukocytes	0.007	0.993	0.000
D84.9 Immunodeficiency, unspecified	0.007	0.993	0.000
D72.8 Other specified disorders of white blood cells	0.007	0.993	0.000
D80 Immunodeficiency with predominantly antibody defects	0.006	0.993	0.001
D73.8 Other diseases of spleen	0.007	0.993	0.000
D84.8 Other specified immunodeficiencies	0.006	0.993	0.000
D84.1 Defects in the complement system	0.006	0.993	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.006	0.993	0.000
D73.3 Abscess of spleen	0.006	0.994	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.006	0.994	0.000
D81.9 Combined immunodeficiency, unspecified	0.006	0.994	0.000
D81.8 Other combined immunodeficiencies	0.006	0.994	0.000
D81.7 Major histocompatibility complex class II deficiency	0.006	0.994	0.000
D81.6 Major histocompatibility complex class I deficiency	0.006	0.994	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.006	0.994	0.000
D81.4 Nezelof's syndrome	0.006	0.994	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.006	0.994	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.006	0.994	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.006	0.994	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.006	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.006	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.006	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.006	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.006	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.006	0.994	0.000
D82.1 Di George's syndrome	0.006	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.006	0.994	0.000
D83.9 Common variable immunodeficiency, unspecified	0.006	0.994	0.000
D83.8 Other common variable immunodeficiencies	0.006	0.994	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.006	0.994	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.006	0.994	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.006	0.994	0.000
C20 Malignant neoplasm of rectum	0.000	0.994	0.006
H52.1 Myopia	0.006	0.994	0.000
D75.0 Familial erythrocytosis	0.006	0.994	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.994	0.006
D73.9 Disease of spleen, unspecified	0.006	0.994	0.000
D73.4 Cyst of spleen	0.006	0.994	0.000
D73.2 Chronic congestive splenomegaly	0.006	0.994	0.000
D73.1 Hypersplenism	0.006	0.994	0.000
D74.9 Methaemoglobinaemia, unspecified	0.005	0.994	0.000
D74.8 Other methaemoglobinaemias	0.005	0.994	0.000
D74.0 Congenital methaemoglobinaemia	0.005	0.994	0.000
D69.6 Thrombocytopenia, unspecified	0.005	0.994	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.006	0.994	0.000
M79.62 Pain in limb (Upper arm)	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
S64 Injury of nerves at wrist and hand level	0.005	0.995	0.000
M16.1 Other primary coxarthrosis	0.000	0.995	0.005
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
D76.3 Other histiocytosis syndromes	0.005	0.995	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.005	0.995	0.001
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.001
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.001
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.001
H50.9 Strabismus, unspecified	0.005	0.995	0.000
H50.2 Vertical strabismus	0.005	0.995	0.000
D73.0 Hyposplenism	0.005	0.995	0.000
D75.2 Essential thrombocytosis	0.005	0.995	0.000
H50 Other strabismus	0.005	0.995	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.005	0.995	0.000
D75.1 Secondary polycythaemia	0.005	0.995	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.995	0.001
M20.4 Other hammer toe(s) (acquired)	0.005	0.995	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.005	0.995	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.004	0.995	0.000
Z96.8 Presence of other specified functional implants	0.004	0.996	0.000
M20.5 Other deformities of toe(s) (acquired)	0.004	0.996	0.000
H53.2 Diplopia	0.000	0.996	0.004
D73.5 Infarction of spleen	0.004	0.996	0.000
H50.5 Heterophoria	0.004	0.996	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.004	0.996	0.000
S64.8 Injury of other nerves at wrist and hand level	0.004	0.996	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.004	0.996	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.004	0.996	0.000
Z92 Personal history of medical treatment	0.004	0.996	0.000
S64.1 Injury of median nerve at wrist and hand level	0.004	0.996	0.000
H50.8 Other specified strabismus	0.004	0.996	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.996	0.004
H50.6 Mechanical strabismus	0.004	0.996	0.000
H50.4 Other and unspecified heterotropia	0.004	0.996	0.000
H50.3 Intermittent heterotropia	0.004	0.996	0.000
M79.6 Pain in limb	0.004	0.996	0.000
D86 Sarcoidosis	0.003	0.996	0.001
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
M79.61 Pain in limb (Shoulder region)	0.004	0.996	0.000
H50.1 Divergent concomitant strabismus	0.004	0.996	0.000
H52 Disorders of refraction and accommodation	0.004	0.996	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.004	0.996	0.000
S64.3 Injury of digital nerve of thumb	0.003	0.996	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.996	0.001
H54 Blindness and low vision	0.000	0.996	0.004
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.996	0.004
H50.0 Convergent concomitant strabismus	0.003	0.997	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.003	0.997	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.997	0.003
C44.5 Skin of trunk	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.003	0.997	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
Z92.9 Personal history of medical treatment, unspecified	0.003	0.997	0.000
Z92.5 Personal history of rehabilitation measures	0.003	0.997	0.000
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
H49 Paralytic strabismus	0.003	0.997	0.000
C22.9 Liver, unspecified	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.002	0.997	0.001
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.001
M20 Acquired deformities of fingers and toes	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
M79.68 Pain in limb (Other)	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
H52.6 Other disorders of refraction	0.003	0.997	0.000
H52.5 Disorders of accommodation	0.003	0.997	0.000
H52.4 Presbyopia	0.003	0.997	0.000
H51 Other disorders of binocular movement	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.997	0.001
D04.5 Skin of trunk	0.003	0.997	0.000
H54.4 Blindness, one eye	0.000	0.997	0.003
H54.6 Unqualified visual loss, one eye	0.000	0.997	0.003
H54.5 Low vision, one eye	0.000	0.997	0.003
H54.3 Unqualified visual loss, both eyes	0.000	0.997	0.003
H54.2 Low vision, both eyes	0.000	0.997	0.003
H54.1 Blindness, one eye, low vision, other eye	0.000	0.997	0.003
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.997	0.001
H92 Otalgia and effusion of ear	0.003	0.997	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
N39.8 Other specified disorders of urinary system	0.003	0.997	0.000
C22.1 Intrahepatic bile duct carcinoma	0.003	0.997	0.000
H52.2 Astigmatism	0.002	0.997	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.003	0.997	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.997	0.002
V18.4 Driver injured in traffic accident	0.000	0.997	0.002
V18.5 Passenger injured in traffic accident	0.000	0.997	0.002
V18.3 Person injured while boarding or alighting	0.000	0.997	0.002
V18.1 Passenger injured in nontraffic accident	0.000	0.997	0.002
D53 Other nutritional anaemias	0.002	0.997	0.000
D04.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
M79.63 Pain in limb (Forearm)	0.002	0.997	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
D04.4 Skin of scalp and neck	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.997	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.002	0.997	0.000
S60-S69 Injuries to the wrist and hand	0.003	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.002	0.997	0.000
H92.2 Otorrhagia	0.002	0.997	0.000
H92.1 Otorrhoea	0.002	0.997	0.000
M20.1 Hallux valgus (acquired)	0.003	0.997	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.003	0.997	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
S69.8 Other specified injuries of wrist and hand	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
H52.0 Hypermetropia	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
Z92.0 Personal history of contraception	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.002	0.998	0.000
Z92.8 Personal history of other medical treatment	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
H51.9 Disorder of binocular movement, unspecified	0.002	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.002	0.998	0.000
H51.2 Internuclear ophthalmoplegia	0.002	0.998	0.000
H51.1 Convergence insufficiency and excess	0.002	0.998	0.000
H51.0 Palsy of conjugate gaze	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
H54.7 Unspecified visual loss	0.000	0.998	0.002
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
S65 Injury of blood vessels at wrist and hand level	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
S69 Other and unspecified injuries of wrist and hand	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.001	0.998	0.001
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
D61 Other aplastic anaemias	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
D52 Folate deficiency anaemia	0.002	0.998	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.998	0.002
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.998	0.002
C62.9 Testis, unspecified	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.000	0.998	0.002
M79.69 Pain in limb (Site unspecified)	0.002	0.998	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
S67 Crushing injury of wrist and hand	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
S65.1 Injury of radial artery at wrist and hand level	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
F60.0 Paranoid personality disorder	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.998	0.002
E89.2 Postprocedural hypoparathyroidism	0.000	0.998	0.002
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
R09.1 Pleurisy	0.002	0.998	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.002	0.998	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.002	0.998	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.002	0.998	0.000
S65.4 Injury of blood vessel(s) of thumb	0.002	0.998	0.000
S65.3 Injury of deep palmar arch	0.002	0.998	0.000
S65.2 Injury of superficial palmar arch	0.002	0.998	0.000
D04.9 Skin, unspecified	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.002	0.998	0.000
S69.7 Multiple injuries of wrist and hand	0.002	0.998	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.002
M79.66 Pain in limb (Lower leg)	0.002	0.998	0.000
M79.64 Pain in limb (Hand)	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.001	0.998	0.001
D04.8 Skin of other sites	0.002	0.998	0.000
D04.1 Skin of eyelid, including canthus	0.002	0.998	0.000
D04.0 Skin of lip	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
S65.5 Injury of blood vessel(s) of other finger	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.001	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.001	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.001	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.001	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
S60.2 Contusion of other parts of wrist and hand	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.998	0.002
H90-H95 Other disorders of ear	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
N39 Other disorders of urinary system	0.002	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.002	0.998	0.000
S60.1 Contusion of finger(s) with damage to nail	0.002	0.998	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.002	0.998	0.000
C22.7 Other specified carcinomas of liver	0.002	0.998	0.000
C22.4 Other sarcomas of liver	0.002	0.998	0.000
C22.3 Angiosarcoma of liver	0.002	0.998	0.000
C22.2 Hepatoblastoma	0.002	0.998	0.000
C54.1 Endometrium	0.002	0.998	0.000
N84.2 Polyp of vagina	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.998	0.002
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.998	0.002
E89.5 Postprocedural testicular hypofunction	0.000	0.998	0.002
E89.4 Postprocedural ovarian failure	0.000	0.998	0.002
E89.1 Postprocedural hypoinsulinaemia	0.000	0.998	0.002
F11.2 Dependence syndrome	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.001	0.998	0.000
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
S60.0 Contusion of finger(s) without damage to nail	0.002	0.998	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.002	0.998	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.002	0.998	0.000
S68.4 Traumatic amputation of hand at wrist level	0.002	0.998	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.002	0.998	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.998	0.002
C53.0 Endocervix	0.002	0.998	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.998	0.001
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.998	0.001
D51.2 Transcobalamin II deficiency	0.001	0.998	0.001
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.998	0.001
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
N43.3 Hydrocele, unspecified	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.001	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
R09.0 Asphyxia	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
F31 Bipolar affective disorder	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.001	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.001	0.998	0.000
C53.1 Exocervix	0.001	0.998	0.000
K60.3 Anal fistula	0.000	0.998	0.002
R59.0 Localised enlarged lymph nodes	0.000	0.998	0.002
D03 Melanoma in situ	0.002	0.998	0.000
D70 Agranulocytosis	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.001	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.998	0.000
N39.2 Orthostatic proteinuria, unspecified	0.001	0.998	0.000
N39.1 Persistent proteinuria, unspecified	0.001	0.998	0.000
C54.9 Corpus uteri, unspecified	0.001	0.998	0.000
C57.0 Fallopian tube	0.001	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.001	0.998	0.000
H02.3 Blepharochalasis	0.000	0.998	0.002
C54 Malignant neoplasm of corpus uteri	0.001	0.998	0.000
D64 Other anaemias	0.001	0.998	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.001	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
G44 Other headache syndromes	0.000	0.998	0.001
C62.1 Descended testis	0.001	0.999	0.000
E83.1 Disorders of iron metabolism	0.001	0.999	0.000
D62 Acute posthaemorrhagic anaemia	0.001	0.999	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.999	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.999	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.999	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.999	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.999	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.999	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.999	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.999	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.999	0.000
S72.10 Pertrochanteric fracture (closed)	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.001	0.999	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.999	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.999	0.001
N83.1 Corpus luteum cyst	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.000	0.999	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.999	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.001	0.999	0.000
F33.8 Other recurrent depressive disorders	0.001	0.999	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.001	0.999	0.000
G44.8 Other specified headache syndromes	0.000	0.999	0.001
H35 Other retinal disorders	0.000	0.999	0.001
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations