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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72795726
log Bayes Factor = 16.0429
Chromosome 10   position 50,871,492  (GRCh37) Explore rs72795726 on Ensembl!
Variant rs72795726 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
M17 Gonarthrosis [arthrosis of knee]
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
M20-M25 Other joint disorders
0.990 0.010 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.988 0.012 0.000
M17.9 Gonarthrosis, unspecified
0.987 0.013 0.000
Chapter VII Diseases of the eye and adnexa
0.984 0.016 0.000
I51 Complications and ill-defined descriptions of heart disease
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.979 0.021 0.000
I51.7 Cardiomegaly
0.977 0.023 0.000
Chapter XIV Diseases of the genitourinary system
0.973 0.027 0.000
Chapter XXI Factors influencing health status and contact with health services
0.968 0.032 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.967 0.033 0.000
N17-N19 Renal failure
0.964 0.036 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
H53-H54 Visual disturbances and blindness
0.959 0.041 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.959 0.041 0.000
M20 Acquired deformities of fingers and toes
0.959 0.041 0.000
J47 Bronchiectasis
0.959 0.041 0.000
N20-N23 Urolithiasis
0.956 0.044 0.000
I50 Heart failure
0.955 0.045 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.954 0.046 0.000
N20 Calculus of kidney and ureter
0.953 0.047 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.951 0.049 0.000
N20.1 Calculus of ureter
0.944 0.056 0.000
H54 Blindness and low vision
0.941 0.059 0.000
I35 Nonrheumatic aortic valve disorders
0.938 0.062 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.937 0.063 0.000
J30-J39 Other diseases of upper respiratory tract
0.935 0.065 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.929 0.071 0.000
N17 Acute renal failure
0.927 0.073 0.000
I73 Other peripheral vascular diseases
0.927 0.073 0.000
S60-S69 Injuries to the wrist and hand
0.924 0.076 0.000
J84 Other interstitial pulmonary diseases
0.913 0.087 0.000
I50.1 Left ventricular failure
0.912 0.088 0.000
M25 Other joint disorders, not elsewhere classified
0.907 0.093 0.000
Chapter V Mental and behavioural disorders
0.901 0.099 0.000
N17.9 Acute renal failure, unspecified
0.901 0.099 0.000
M20.1 Hallux valgus (acquired)
0.898 0.102 0.000
E70-E90 Metabolic disorders
0.896 0.104 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.893 0.107 0.000
I38 Endocarditis, valve unspecified
0.892 0.108 0.000
N18 Chronic renal failure
0.890 0.110 0.000
M20.5 Other deformities of toe(s) (acquired)
0.889 0.111 0.000
J09-J18 Influenza and pneumonia
0.885 0.115 0.000
H30-H36 Disorders of choroid and retina
0.884 0.116 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.883 0.117 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.876 0.124 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.876 0.124 0.000
M80-M85 Disorders of bone density and structure
0.876 0.124 0.000
M05-M14 Inflammatory polyarthropathies
0.876 0.124 0.000
I73.0 Raynaud's syndrome
0.874 0.126 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.873 0.127 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.873 0.127 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.865 0.135 0.000
F30-F39 Mood [affective] disorders
0.865 0.135 0.000
M16 Coxarthrosis [arthrosis of hip]
0.863 0.137 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.863 0.137 0.000
B95-B98 Bacterial, viral and other infectious agents
0.861 0.139 0.000
M17.0 Primary gonarthrosis, bilateral
0.860 0.140 0.000
M19 Other arthrosis
0.859 0.141 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.857 0.143 0.000
M17.1 Other primary gonarthrosis
0.856 0.144 0.000
J43 Emphysema
0.852 0.148 0.000
A30-A49 Other bacterial diseases
0.845 0.155 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.843 0.157 0.000
Chapter XXII Codes for special purposes
0.837 0.163 0.000
H54.7 Unspecified visual loss
0.837 0.163 0.000
S00-S09 Injuries to the head
0.836 0.164 0.000
H54.4 Blindness, one eye
0.831 0.169 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.829 0.171 0.000
I50.0 Congestive heart failure
0.829 0.171 0.000
S20-S29 Injuries to the thorax
0.829 0.171 0.000
Chapter XX External causes of morbidity and mortality
0.829 0.171 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.827 0.173 0.000
N20.0 Calculus of kidney
0.825 0.175 0.000
M65-M68 Disorders of synovium and tendon
0.824 0.176 0.000
Z82.3 Family history of stroke
0.823 0.177 0.000
Z96 Presence of other functional implants
0.823 0.177 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.823 0.177 0.000
H54.0 Blindness, both eyes
0.819 0.181 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.818 0.182 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.817 0.183 0.000
Z89 Acquired absence of limb
0.816 0.184 0.000
Chapter VIII Diseases of the ear and mastoid process
0.816 0.184 0.000
N10-N16 Renal tubulo-interstitial diseases
0.813 0.187 0.000
M31 Other necrotising vasculopathies
0.810 0.189 0.000
I73.9 Peripheral vascular disease, unspecified
0.805 0.195 0.000
J40 Bronchitis, not specified as acute or chronic
0.805 0.195 0.000
A00-A09 Intestinal infectious diseases
0.805 0.195 0.000
M19.0 Primary arthrosis of other joints
0.803 0.197 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.800 0.200 0.000
M25.7 Osteophyte
0.800 0.200 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.798 0.202 0.000
I60-I69 Cerebrovascular diseases
0.798 0.202 0.000
I35.0 Aortic (valve) stenosis
0.798 0.202 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.798 0.202 0.000
S80-S89 Injuries to the knee and lower leg
0.797 0.203 0.000
Z93 Artificial opening status
0.794 0.206 0.000
J32 Chronic sinusitis
0.793 0.207 0.000
Z94 Transplanted organ and tissue status
0.791 0.209 0.000
M17.3 Other posttraumatic gonarthrosis
0.790 0.210 0.000
M10 Gout
0.790 0.210 0.000
H55-H59 Other disorders of eye and adnexa
0.790 0.210 0.000
F33 Recurrent depressive disorder
0.790 0.210 0.000
J60-J70 Lung diseases due to external agents
0.788 0.212 0.000
N18.9 Chronic renal failure, unspecified
0.788 0.212 0.000
J18 Pneumonia, organism unspecified
0.787 0.213 0.000
B35-B49 Mycoses
0.785 0.215 0.000
S67 Crushing injury of wrist and hand
0.783 0.217 0.000
J81 Pulmonary oedema
0.782 0.218 0.000
I77 Other disorders of arteries and arterioles
0.782 0.218 0.000
S62 Fracture at wrist and hand level
0.781 0.219 0.000
M16.1 Other primary coxarthrosis
0.780 0.220 0.000
H40-H42 Glaucoma
0.780 0.220 0.000
N19 Unspecified renal failure
0.780 0.220 0.000
T66-T78 Other and unspecified effects of external causes
0.779 0.220 0.000
Z97 Presence of other devices
0.778 0.222 0.000
T93 Sequelae of injuries of lower limb
0.777 0.223 0.000
Z80 Family history of malignant neoplasm
0.777 0.223 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.776 0.224 0.000
H33 Retinal detachments and breaks
0.770 0.230 0.000
H35 Other retinal disorders
0.770 0.230 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.770 0.230 0.000
M00-M03 Infectious arthropathies
0.766 0.234 0.000
L40-L45 Papulosquamous disorders
0.764 0.236 0.000
H54.9 Unspecified visual impairment (binocular)
0.763 0.237 0.000
Chapter VI Diseases of the nervous system
0.762 0.238 0.000
N20.2 Calculus of kidney with calculus of ureter
0.761 0.239 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.759 0.241 0.000
M34 Systemic sclerosis
0.759 0.241 0.000
N18.0 End-stage renal disease
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.758 0.242 0.000
J33 Nasal polyp
0.756 0.244 0.000
J38.2 Nodules of vocal cords
0.756 0.244 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.753 0.246 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.753 0.247 0.000
E65-E68 Obesity and other hyperalimentation
0.753 0.247 0.000
M81 Osteoporosis without pathological fracture
0.751 0.249 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.751 0.249 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.750 0.250 0.000
I33 Acute and subacute endocarditis
0.748 0.252 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
J43.9 Emphysema, unspecified
0.746 0.254 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.746 0.254 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.746 0.254 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.745 0.255 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.739 0.261 0.000
I35.8 Other aortic valve disorders
0.738 0.261 0.000
J38.7 Other diseases of larynx
0.738 0.262 0.000
F31 Bipolar affective disorder
0.737 0.263 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.264 0.000
H10-H13 Disorders of conjunctiva
0.736 0.264 0.000
I35.1 Aortic (valve) insufficiency
0.736 0.264 0.000
N20.9 Urinary calculus, unspecified
0.734 0.266 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.733 0.267 0.000
Z02 Examination and encounter for administrative purposes
0.731 0.269 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.731 0.269 0.000
M10.9 Gout, unspecified
0.729 0.271 0.000
J38.3 Other diseases of vocal cords
0.729 0.271 0.000
L60-L75 Disorders of skin appendages
0.728 0.272 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.728 0.272 0.000
E87.7 Fluid overload
0.726 0.274 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.726 0.274 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.726 0.274 0.000
M20.0 Deformity of finger(s)
0.725 0.275 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.725 0.275 0.000
M25.4 Effusion of joint
0.724 0.276 0.000
E20-E35 Disorders of other endocrine glands
0.724 0.276 0.000
M21 Other acquired deformities of limbs
0.723 0.276 0.000
T79-T79 Certain early complications of trauma
0.722 0.277 0.000
E87.6 Hypokalaemia
0.722 0.278 0.000
S90-S99 Injuries to the ankle and foot
0.721 0.279 0.000
M40-M43 Deforming dorsopathies
0.721 0.279 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.721 0.279 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.721 0.279 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.720 0.280 0.000
N25-N29 Other disorders of kidney and ureter
0.720 0.280 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.718 0.281 0.000
S61 Open wound of wrist and hand
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
E50-E64 Other nutritional deficiencies
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
M15 Polyarthrosis
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
E83 Disorders of mineral metabolism
0.716 0.284 0.000
I70 Atherosclerosis
0.716 0.284 0.000
M17.5 Other secondary gonarthrosis
0.715 0.285 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.715 0.285 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
M65 Synovitis and tenosynovitis
0.713 0.286 0.000
B25-B34 Other viral diseases
0.713 0.287 0.000
J42 Unspecified chronic bronchitis
0.713 0.287 0.000
M20.2 Hallux rigidus
0.712 0.288 0.000
I72 Other aneurysm
0.712 0.288 0.000
N13 Obstructive and reflux uropathy
0.711 0.289 0.000
E87.5 Hyperkalaemia
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M33 Dermatopolymyositis
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.709 0.291 0.000
M25.77 Osteophyte (Ankle and foot)
0.708 0.292 0.000
J18.1 Lobar pneumonia, unspecified
0.707 0.293 0.000
L50-L54 Urticaria and erythema
0.707 0.293 0.000
Z83 Family history of other specific disorders
0.707 0.293 0.000
J38.4 Oedema of larynx
0.706 0.294 0.000
A41 Other septicaemia
0.705 0.295 0.000
I34 Nonrheumatic mitral valve disorders
0.705 0.295 0.000
I51.6 Cardiovascular disease, unspecified
0.704 0.296 0.000
I51.5 Myocardial degeneration
0.704 0.296 0.000
I51.4 Myocarditis, unspecified
0.704 0.296 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.704 0.296 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.704 0.296 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.704 0.296 0.000
I51.0 Cardiac septal defect, acquired
0.704 0.296 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
H35.3 Degeneration of macula and posterior pole
0.704 0.296 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.702 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
B65-B83 Helminthiases
0.702 0.298 0.000
B50-B64 Protozoal diseases
0.702 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
H53 Visual disturbances
0.701 0.299 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.701 0.299 0.000
F32 Depressive episode
0.701 0.299 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.700 0.299 0.000
E87.0 Hyperosmolality and hypernatraemia
0.700 0.300 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.301 0.000
M35 Other systemic involvement of connective tissue
0.699 0.301 0.000
J80 Adult respiratory distress syndrome
0.698 0.302 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.698 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.697 0.303 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.697 0.303 0.000
M23 Internal derangement of knee
0.695 0.305 0.000
J95-J99 Other diseases of the respiratory system
0.695 0.305 0.000
I31 Other diseases of pericardium
0.694 0.306 0.000
S02 Fracture of skull and facial bones
0.693 0.307 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.693 0.307 0.000
N18.4 Chronic kidney disease, stage 4
0.692 0.308 0.000
I71 Aortic aneurysm and dissection
0.692 0.308 0.000
S01 Open wound of head
0.692 0.308 0.000
Z92 Personal history of medical treatment
0.691 0.309 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.689 0.311 0.000
Z89.6 Acquired absence of leg above knee
0.689 0.311 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.688 0.312 0.000
B02 Zoster [herpes zoster]
0.687 0.313 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.686 0.314 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.685 0.314 0.000
T93.2 Sequelae of other fractures of lower limb
0.685 0.315 0.000
J32.9 Chronic sinusitis, unspecified
0.685 0.315 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.684 0.316 0.000
N00-N08 Glomerular diseases
0.683 0.317 0.000
I35.9 Aortic valve disorder, unspecified
0.683 0.317 0.000
I45 Other conduction disorders
0.682 0.317 0.000
M25.8 Other specified joint disorders
0.682 0.318 0.000
A49 Bacterial infection of unspecified site
0.682 0.318 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.682 0.318 0.000
H65-H75 Diseases of middle ear and mastoid
0.682 0.318 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.682 0.318 0.000
M31.6 Other giant cell arteritis
0.682 0.318 0.000
Z84 Family history of other conditions
0.682 0.318 0.000
Z81 Family history of mental and behavioural disorders
0.682 0.318 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.681 0.318 0.000
S20 Superficial injury of thorax
0.681 0.319 0.000
E86 Volume depletion
0.681 0.319 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.681 0.319 0.000
J33.8 Other polyp of sinus
0.681 0.319 0.000
I51.9 Heart disease, unspecified
0.680 0.320 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.680 0.320 0.000
L40 Psoriasis
0.680 0.320 0.000
A04 Other bacterial intestinal infections
0.679 0.321 0.000
Z95.1 Presence of aortocoronary bypass graft
0.679 0.321 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.678 0.322 0.000
Z96.0 Presence of urogenital implants
0.677 0.323 0.000
J10 Influenza due to identified influenza virus
0.677 0.323 0.000
F33.9 Recurrent depressive disorder, unspecified
0.676 0.324 0.000
M16.0 Primary coxarthrosis, bilateral
0.676 0.324 0.000
Z63 Other problems related to primary support group, including family circumstances
0.675 0.325 0.000
M22 Disorders of patella
0.675 0.325 0.000
H33.2 Serous retinal detachment
0.675 0.325 0.000
H54.6 Unqualified visual loss, one eye
0.675 0.325 0.000
H54.5 Low vision, one eye
0.675 0.325 0.000
H54.3 Unqualified visual loss, both eyes
0.675 0.325 0.000
H54.2 Low vision, both eyes
0.675 0.325 0.000
H54.1 Blindness, one eye, low vision, other eye
0.675 0.325 0.000
Z96.6 Presence of orthopaedic joint implants
0.674 0.326 0.000
S70-S79 Injuries to the hip and thigh
0.673 0.326 0.000
E40-E46 Malnutrition
0.672 0.328 0.000
M19.1 Posttraumatic arthrosis of other joints
0.671 0.329 0.000
J37 Chronic laryngitis and laryngotracheitis
0.670 0.330 0.000
Z56 Problems related to employment and unemployment
0.670 0.330 0.000
M85 Other disorders of bone density and structure
0.670 0.330 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.669 0.331 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.668 0.332 0.000
T59 Toxic effect of other gases, fumes and vapours
0.667 0.332 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.667 0.333 0.000
J00-J06 Acute upper respiratory infections
0.666 0.334 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.666 0.334 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.666 0.334 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.666 0.334 0.000
Z82.2 Family history of deafness and hearing loss
0.666 0.334 0.000
Z82.1 Family history of blindness and visual loss
0.666 0.334 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.666 0.334 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.666 0.334 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.665 0.335 0.000
N17.8 Other acute renal failure
0.665 0.335 0.000
N17.2 Acute renal failure with medullary necrosis
0.665 0.335 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.665 0.335 0.000
N17.0 Acute renal failure with tubular necrosis
0.665 0.335 0.000
Z94.0 Kidney transplant status
0.665 0.335 0.000
I73.8 Other specified peripheral vascular diseases
0.665 0.335 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.665 0.335 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.664 0.336 0.000
Z93.2 Ileostomy status
0.664 0.336 0.000
S82 Fracture of lower leg, including ankle
0.664 0.336 0.000
S69 Other and unspecified injuries of wrist and hand
0.663 0.337 0.000
S65 Injury of blood vessels at wrist and hand level
0.663 0.337 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.663 0.337 0.000
S60 Superficial injury of wrist and hand
0.663 0.337 0.000
M84 Disorders of continuity of bone
0.661 0.339 0.000
M18 Arthrosis of first carpometacarpal joint
0.661 0.339 0.000
S50-S59 Injuries to the elbow and forearm
0.660 0.340 0.000
Q80-Q89 Other congenital malformations
0.660 0.340 0.000
M05 Seropositive rheumatoid arthritis
0.659 0.341 0.000
M20.3 Other deformity of hallux (acquired)
0.658 0.341 0.000
Z98 Other postsurgical states
0.657 0.343 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.657 0.343 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.656 0.344 0.000
N99-N99 Other disorders of the genitourinary system
0.656 0.344 0.000
I63 Cerebral infarction
0.656 0.344 0.000
I42 Cardiomyopathy
0.655 0.345 0.000
W20-W49 Exposure to inanimate mechanical forces
0.655 0.345 0.000
F60-F69 Disorders of adult personality and behaviour
0.654 0.345 0.000
J84.8 Other specified interstitial pulmonary diseases
0.654 0.345 0.000
J84.0 Alveolar and parietoalveolar conditions
0.654 0.345 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.654 0.346 0.000
J20-J22 Other acute lower respiratory infections
0.654 0.346 0.000
E87.2 Acidosis
0.653 0.347 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.652 0.348 0.000
D50-D53 Nutritional anaemias
0.652 0.348 0.000
Z02.8 Other examinations for administrative purposes
0.651 0.349 0.000
M25.9 Joint disorder, unspecified
0.651 0.349 0.000
M25.3 Other instability of joint
0.651 0.349 0.000
M25.2 Flail joint
0.651 0.349 0.000
M25.1 Fistula of joint
0.651 0.349 0.000
M25.0 Haemarthrosis
0.651 0.349 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.650 0.350 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.650 0.350 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.649 0.351 0.000
N71 Inflammatory disease of uterus, except cervix
0.649 0.351 0.000
J39 Other diseases of upper respiratory tract
0.649 0.351 0.000
M24 Other specific joint derangements
0.648 0.352 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.647 0.353 0.000
H57 Other disorders of eye and adnexa
0.647 0.353 0.000
F99-F99 Unspecified mental disorder
0.646 0.354 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.646 0.354 0.000
F80-F89 Disorders of psychological development
0.646 0.354 0.000
F70-F79 Mental retardation
0.646 0.354 0.000
M16.7 Other secondary coxarthrosis
0.646 0.354 0.000
T92 Sequelae of injuries of upper limb
0.646 0.354 0.000
B37 Candidiasis
0.645 0.354 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.645 0.355 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.645 0.355 0.000
S40-S49 Injuries to the shoulder and upper arm
0.645 0.355 0.000
M81.9 Osteoporosis, unspecified
0.643 0.357 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.643 0.357 0.000
E85 Amyloidosis
0.643 0.357 0.000
E84 Cystic fibrosis
0.643 0.357 0.000
E79 Disorders of purine and pyrimidine metabolism
0.643 0.357 0.000
E77 Disorders of glycoprotein metabolism
0.643 0.357 0.000
E76 Disorders of glycosaminoglycan metabolism
0.643 0.357 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.643 0.357 0.000
E74 Other disorders of carbohydrate metabolism
0.643 0.357 0.000
E73 Lactose intolerance
0.643 0.357 0.000
E72 Other disorders of amino-acid metabolism
0.643 0.357 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.643 0.357 0.000
E70 Disorders of aromatic amino-acid metabolism
0.643 0.357 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.643 0.357 0.000
Z89.5 Acquired absence of leg at or below knee
0.642 0.358 0.000
H33.5 Other retinal detachments
0.642 0.358 0.000
L20-L30 Dermatitis and eczema
0.640 0.359 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.640 0.360 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.640 0.360 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.640 0.360 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.640 0.360 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.640 0.360 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.640 0.360 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.640 0.360 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.640 0.360 0.000
T36 Poisoning by systemic antibiotics
0.640 0.360 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.640 0.360 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.639 0.361 0.000
N18.8 Other chronic renal failure
0.638 0.362 0.000
N18.1 Chronic kidney disease, stage 1
0.638 0.362 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.638 0.362 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.638 0.362 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.638 0.362 0.000
S68 Traumatic amputation of wrist and hand
0.638 0.362 0.000
M25.74 Osteophyte (Hand)
0.638 0.362 0.000
X50-X57 Overexertion, travel and privation
0.637 0.363 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.637 0.363 0.000
E88 Other metabolic disorders
0.636 0.364 0.000
T90 Sequelae of injuries of head
0.636 0.364 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.635 0.365 0.000
J17 Pneumonia in diseases classified elsewhere
0.634 0.365 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.634 0.365 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.634 0.365 0.000
J12 Viral pneumonia, not elsewhere classified
0.634 0.365 0.000
J11 Influenza, virus not identified
0.634 0.365 0.000
J14 Pneumonia due to Haemophilus influenzae
0.634 0.365 0.000
J09 Influenza due to certain identified influenza virus
0.634 0.365 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.634 0.366 0.000
H31 Other disorders of choroid
0.634 0.366 0.000
H30 Chorioretinal inflammation
0.634 0.366 0.000
H40 Glaucoma
0.634 0.366 0.000
J32.4 Chronic pansinusitis
0.634 0.366 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.633 0.366 0.000
J38.6 Stenosis of larynx
0.633 0.367 0.000
J38.5 Laryngeal spasm
0.633 0.367 0.000
J38.0 Paralysis of vocal cords and larynx
0.633 0.367 0.000
V10-V19 Pedal cyclist injured in transport accident
0.633 0.367 0.000
I78 Diseases of capillaries
0.633 0.367 0.000
H43-H45 Disorders of vitreous body and globe
0.633 0.367 0.000
T51 Toxic effect of alcohol
0.633 0.367 0.000
I74 Arterial embolism and thrombosis
0.633 0.367 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.633 0.367 0.000
M65.3 Trigger finger
0.632 0.367 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.632 0.368 0.000
Z60 Problems related to social environment
0.632 0.368 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.632 0.368 0.000
M07 Psoriatic and enteropathic arthropathies
0.630 0.369 0.000
M80 Osteoporosis with pathological fracture
0.629 0.371 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.629 0.371 0.000
Q00-Q07 Congenital malformations of the nervous system
0.629 0.371 0.000
M13 Other arthritis
0.629 0.371 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.629 0.371 0.000
I77.8 Other specified disorders of arteries and arterioles
0.628 0.372 0.000
T98 Sequelae of other and unspecified effects of external causes
0.628 0.372 0.000
T95 Sequelae of burns, corrosions and frostbite
0.628 0.372 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.628 0.372 0.000
T91 Sequelae of injuries of neck and trunk
0.628 0.372 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.628 0.372 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.628 0.372 0.000
T87 Complications peculiar to reattachment and amputation
0.628 0.372 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.628 0.372 0.000
I10-I15 Hypertensive diseases
0.628 0.372 0.000
M83 Adult osteomalacia
0.628 0.372 0.000
M82 Osteoporosis in diseases classified elsewhere
0.628 0.372 0.000
Z93.0 Tracheostomy status
0.628 0.372 0.000
M14 Arthropathies in other diseases classified elsewhere
0.628 0.372 0.000
M12 Other specific arthropathies
0.628 0.372 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.628 0.372 0.000
M08 Juvenile arthritis
0.628 0.372 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.628 0.372 0.000
J46 Status asthmaticus
0.627 0.372 0.000
I99 Other and unspecified disorders of circulatory system
0.627 0.372 0.000
Z95.3 Presence of xenogenic heart valve
0.626 0.374 0.000
L10-L14 Bullous disorders
0.626 0.374 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.625 0.375 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.625 0.375 0.000
T81 Complications of procedures, not elsewhere classified
0.624 0.376 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.624 0.376 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.623 0.377 0.000
T78 Adverse effects, not elsewhere classified
0.622 0.378 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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