TreeWAS – Variant ID: rs72902579

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.002	0.998
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.005	0.995
I25.1 Atherosclerotic heart disease	0.000	0.006	0.994
I20 Angina pectoris	0.000	0.009	0.991
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.025	0.975
I24 Other acute ischaemic heart diseases	0.000	0.045	0.955
I25.2 Old myocardial infarction	0.000	0.048	0.952
I20.9 Angina pectoris, unspecified	0.000	0.056	0.944
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.058	0.942
I20.0 Unstable angina	0.000	0.062	0.938
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.063	0.937
Z95.1 Presence of aortocoronary bypass graft	0.000	0.096	0.904
I24.8 Other forms of acute ischaemic heart disease	0.000	0.097	0.903
I20.8 Other forms of angina pectoris	0.000	0.139	0.861
I21.4 Acute subendocardial myocardial infarction	0.000	0.152	0.848
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.160	0.840
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.173	0.827
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.177	0.823
I22 Subsequent myocardial infarction	0.000	0.203	0.797
I25.3 Aneurysm of heart	0.000	0.213	0.787
I21.9 Acute myocardial infarction, unspecified	0.000	0.217	0.783
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.236	0.764
I25.5 Ischaemic cardiomyopathy	0.000	0.266	0.734
Z95.0 Presence of cardiac pacemaker	0.000	0.269	0.731
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.279	0.721
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.4 Coronary artery aneurysm	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.284	0.715
I24.1 Dressler's syndrome	0.000	0.315	0.684
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.326	0.674
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.353	0.646
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.356	0.644
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.373	0.627
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.385	0.615
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.428	0.572
I22.8 Subsequent myocardial infarction of other sites	0.000	0.428	0.572
I20.1 Angina pectoris with documented spasm	0.000	0.445	0.554
E78.5 Hyperlipidaemia, unspecified	0.000	0.464	0.536
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.467	0.533
Z95.2 Presence of prosthetic heart valve	0.000	0.483	0.517
I23.8 Other current complications following acute myocardial infarction	0.000	0.486	0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.486	0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
Z95.3 Presence of xenogenic heart valve	0.000	0.529	0.471
E78.2 Mixed hyperlipidaemia	0.000	0.555	0.445
Z95.4 Presence of other heart-valve replacement	0.000	0.564	0.436
E78.6 Lipoprotein deficiency	0.000	0.589	0.410
E78.3 Hyperchylomicronaemia	0.000	0.589	0.410
E78.1 Pure hyperglyceridaemia	0.000	0.613	0.387
E78.4 Other hyperlipidaemia	0.000	0.624	0.376
E78.8 Other disorders of lipoprotein metabolism	0.000	0.666	0.334
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.676	0.324
I44.7 Left bundle-branch block, unspecified	0.000	0.921	0.079
I44 Atrioventricular and left bundle-branch block	0.000	0.924	0.076
I45.1 Other and unspecified right bundle-branch block	0.000	0.926	0.074
I30-I52 Other forms of heart disease	0.000	0.926	0.074
I45 Other conduction disorders	0.000	0.927	0.073
Chapter IX Diseases of the circulatory system	0.000	0.929	0.071
I49 Other cardiac arrhythmias	0.000	0.930	0.070
I49.3 Ventricular premature depolarisation	0.000	0.932	0.068
I45.9 Conduction disorder, unspecified	0.000	0.938	0.062
I44.3 Other and unspecified atrioventricular block	0.000	0.938	0.062
I30 Acute pericarditis	0.000	0.940	0.059
I44.0 Atrioventricular block, first degree	0.000	0.941	0.059
I49.9 Cardiac arrhythmia, unspecified	0.000	0.941	0.059
I49.4 Other and unspecified premature depolarisation	0.000	0.945	0.055
I44.1 Atrioventricular block, second degree	0.000	0.945	0.055
I49.1 Atrial premature depolarisation	0.000	0.945	0.055
I44.6 Other and unspecified fascicular block	0.000	0.945	0.055
I44.5 Left posterior fascicular block	0.000	0.945	0.055
I44.4 Left anterior fascicular block	0.000	0.945	0.055
I36 Nonrheumatic tricuspid valve disorders	0.000	0.945	0.055
I38 Endocarditis, valve unspecified	0.000	0.946	0.054
I49.0 Ventricular fibrillation and flutter	0.000	0.947	0.053
I52 Other heart disorders in diseases classified elsewhere	0.000	0.947	0.053
I48 Atrial fibrillation and flutter	0.000	0.947	0.053
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.947	0.053
I41 Myocarditis in diseases classified elsewhere	0.000	0.947	0.053
I40 Acute myocarditis	0.000	0.947	0.053
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.947	0.053
I37 Pulmonary valve disorders	0.000	0.947	0.053
I32 Pericarditis in diseases classified elsewhere	0.000	0.947	0.053
I45.8 Other specified conduction disorders	0.000	0.947	0.053
I45.4 Nonspecific intraventricular block	0.000	0.947	0.053
I45.3 Trifascicular block	0.000	0.947	0.053
I45.0 Right fascicular block	0.000	0.947	0.053
I42 Cardiomyopathy	0.000	0.947	0.052
I00-I02 Acute rheumatic fever	0.000	0.949	0.051
I49.2 Junctional premature depolarisation	0.000	0.950	0.050
I30.9 Acute pericarditis, unspecified	0.000	0.950	0.049
I45.6 Preexcitation syndrome	0.000	0.953	0.047
I45.5 Other specified heart block	0.000	0.953	0.047
M24 Other specific joint derangements	0.047	0.953	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.953	0.047
M20-M25 Other joint disorders	0.045	0.955	0.000
I45.2 Bifascicular block	0.000	0.955	0.044
I33 Acute and subacute endocarditis	0.000	0.955	0.044
M24.5 Contracture of joint	0.044	0.956	0.000
I46 Cardiac arrest	0.000	0.956	0.044
M35 Other systemic involvement of connective tissue	0.043	0.957	0.000
I30.8 Other forms of acute pericarditis	0.000	0.957	0.043
I30.1 Infective pericarditis	0.000	0.957	0.043
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.957	0.043
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.957	0.043
M35.3 Polymyalgia rheumatica	0.042	0.958	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.958	0.042
M24.1 Other articular cartilage disorders	0.041	0.958	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.959	0.041
M22 Disorders of patella	0.041	0.959	0.000
I44.2 Atrioventricular block, complete	0.000	0.959	0.041
I51 Complications and ill-defined descriptions of heart disease	0.000	0.959	0.041
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.959	0.041
I50 Heart failure	0.000	0.960	0.040
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.961	0.039
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.961	0.039
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.961	0.039
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.961	0.039
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.961	0.039
M24.56 Contracture of joint (Lower leg)	0.038	0.962	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.962	0.038
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.962	0.038
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.962	0.038
I37.9 Pulmonary valve disorder, unspecified	0.000	0.962	0.038
I37.8 Other pulmonary valve disorders	0.000	0.962	0.038
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.962	0.038
I37.1 Pulmonary valve insufficiency	0.000	0.962	0.038
I37.0 Pulmonary valve stenosis	0.000	0.962	0.038
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.962	0.038
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.962	0.038
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.962	0.038
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.962	0.038
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.962	0.038
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.962	0.038
I40.9 Acute myocarditis, unspecified	0.000	0.962	0.038
I40.8 Other acute myocarditis	0.000	0.962	0.038
I40.1 Isolated myocarditis	0.000	0.962	0.038
I40.0 Infective myocarditis	0.000	0.962	0.038
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.962	0.038
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.962	0.038
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.962	0.038
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.962	0.038
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.962	0.038
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.962	0.038
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.962	0.038
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.962	0.038
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.962	0.038
I48.4 Atypical atrial flutter	0.000	0.962	0.038
I48.3 Typical atrial flutter	0.000	0.962	0.038
I48.2 Chronic atrial fibrillation	0.000	0.962	0.038
I48.1 Persistent atrial fibrillation	0.000	0.962	0.038
I48.0 Paroxysmal atrial fibrillation	0.000	0.962	0.038
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.962	0.038
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.962	0.038
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.962	0.038
I49.8 Other specified cardiac arrhythmias	0.000	0.962	0.038
M23 Internal derangement of knee	0.038	0.962	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.962	0.038
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.962	0.038
I42.6 Alcoholic cardiomyopathy	0.000	0.962	0.038
I42.5 Other restrictive cardiomyopathy	0.000	0.962	0.038
I42.4 Endocardial fibroelastosis	0.000	0.962	0.038
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.962	0.038
M24.4 Recurrent dislocation and subluxation of joint	0.038	0.962	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.038	0.962	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.962	0.037
M31 Other necrotising vasculopathies	0.037	0.963	0.000
I02 Rheumatic chorea	0.000	0.963	0.037
I01 Rheumatic fever with heart involvement	0.000	0.963	0.037
I00 Rheumatic fever without mention of heart involvement	0.000	0.963	0.037
M24.54 Contracture of joint (Hand)	0.037	0.963	0.000
I31 Other diseases of pericardium	0.000	0.963	0.037
I42.0 Dilated cardiomyopathy	0.000	0.964	0.036
M25 Other joint disorders, not elsewhere classified	0.036	0.964	0.000
M24.2 Disorder of ligament	0.036	0.964	0.000
M24.51 Contracture of joint (Shoulder region)	0.036	0.964	0.000
I35.8 Other aortic valve disorders	0.000	0.964	0.036
I35.0 Aortic (valve) stenosis	0.000	0.964	0.036
M22.4 Chondromalacia patellae	0.036	0.964	0.000
M22.8 Other disorders of patella	0.036	0.964	0.000
I51.9 Heart disease, unspecified	0.000	0.964	0.036
I05-I09 Chronic rheumatic heart diseases	0.000	0.964	0.035
M30 Polyarteritis nodosa and related conditions	0.035	0.964	0.000
M24.0 Loose body in joint	0.035	0.965	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.965	0.035
M24.8 Other specific joint derangements, not elsewhere classified	0.035	0.965	0.000
M23.5 Chronic instability of knee	0.035	0.965	0.000
M35.7 Hypermobility syndrome	0.034	0.966	0.000
M31.3 Wegener's granulomatosis	0.034	0.966	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.034	0.966	0.000
M24.9 Joint derangement, unspecified	0.034	0.966	0.000
M24.7 Protrusio acetabuli	0.034	0.966	0.000
M24.6 Ankylosis of joint	0.034	0.966	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.034	0.966	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.966	0.034
M23.4 Loose body in knee	0.033	0.967	0.000
I49.5 Sick sinus syndrome	0.000	0.967	0.032
I27 Other pulmonary heart diseases	0.000	0.967	0.033
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.032	0.967	0.000
M33 Dermatopolymyositis	0.032	0.967	0.000
M32 Systemic lupus erythematosus	0.032	0.967	0.000
M21 Other acquired deformities of limbs	0.032	0.968	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.032	0.968	0.000
M25.8 Other specified joint disorders	0.032	0.968	0.000
M34 Systemic sclerosis	0.032	0.968	0.000
I33.9 Acute endocarditis, unspecified	0.000	0.968	0.032
M24.59 Contracture of joint (Site unspecified)	0.032	0.968	0.000
M24.58 Contracture of joint (Other)	0.032	0.968	0.000
M24.57 Contracture of joint (Ankle and foot)	0.032	0.968	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.032	0.968	0.000
M24.53 Contracture of joint (Forearm)	0.032	0.968	0.000
M24.52 Contracture of joint (Upper arm)	0.032	0.968	0.000
M24.50 Contracture of joint (Multiple sites)	0.032	0.968	0.000
I46.1 Sudden cardiac death, so described	0.000	0.968	0.032
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.031	0.969	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.031	0.969	0.000
M35.8 Other specified systemic involvement of connective tissue	0.031	0.969	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.031	0.969	0.000
M35.5 Multifocal fibrosclerosis	0.031	0.969	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.031	0.969	0.000
M35.2 Behcet's disease	0.031	0.969	0.000
M35.1 Other overlap syndromes	0.031	0.969	0.000
I42.8 Other cardiomyopathies	0.000	0.969	0.031
I28 Other diseases of pulmonary vessels	0.000	0.969	0.031
M22.3 Other derangements of patella	0.030	0.970	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.030	0.970	0.000
M24.18 Other articular cartilage disorders (Other)	0.030	0.970	0.000
M24.14 Other articular cartilage disorders (Hand)	0.030	0.970	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.030	0.970	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.030	0.970	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.030	0.970	0.000
M22.1 Recurrent subluxation of patella	0.030	0.970	0.000
M22.9 Disorder of patella, unspecified	0.030	0.970	0.000
M22.0 Recurrent dislocation of patella	0.030	0.970	0.000
I51.5 Myocardial degeneration	0.000	0.970	0.030
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.970	0.030
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.970	0.030
I51.0 Cardiac septal defect, acquired	0.000	0.970	0.030
M23.6 Other spontaneous disruption of ligament(s) of knee	0.030	0.970	0.000
M23.8 Other internal derangements of knee	0.030	0.970	0.000
M25.3 Other instability of joint	0.029	0.971	0.000
M22.2 Patellofemoral disorders	0.029	0.971	0.000
I50.0 Congestive heart failure	0.000	0.971	0.029
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.029	0.971	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.971	0.029
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.029	0.971	0.000
M25.7 Osteophyte	0.029	0.971	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.971	0.028
M23.49 Loose body in knee-Unspec lig/men	0.028	0.972	0.000
I51.8 Other ill-defined heart diseases	0.000	0.972	0.028
I51.4 Myocarditis, unspecified	0.000	0.972	0.028
M24.07 Loose body in joint (Ankle and foot)	0.028	0.972	0.000
M24.23 Disorder of ligament (Forearm)	0.028	0.972	0.000
M25.5 Pain in joint	0.028	0.972	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.972	0.028
M23.9 Internal derangement of knee, unspecified	0.028	0.972	0.000
M23.1 Discoid meniscus (congenital)	0.028	0.972	0.000
M23.0 Cystic meniscus	0.028	0.972	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.972	0.027
M25.87 Other specified joint disorders (Ankle and foot)	0.027	0.972	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.027	0.973	0.000
M25.83 Other specified joint disorders (Forearm)	0.027	0.973	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.027	0.973	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.027	0.973	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.027	0.973	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.027	0.973	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.027	0.973	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.027	0.973	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.027	0.973	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.027	0.973	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.027	0.973	0.000
I50.1 Left ventricular failure	0.000	0.973	0.027
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.973	0.027
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.973	0.027
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.973	0.027
M31.9 Necrotising vasculopathy, unspecified	0.027	0.973	0.000
M31.8 Other specified necrotising vasculopathies	0.027	0.973	0.000
M31.7 Microscopic polyangiitis	0.027	0.973	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.027	0.973	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.027	0.973	0.000
M31.2 Lethal midline granuloma	0.027	0.973	0.000
M31.1 Thrombotic microangiopathy	0.027	0.973	0.000
M31.0 Hypersensitivity angiitis	0.027	0.973	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.973	0.027
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.973	0.027
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.973	0.026
I01.8 Other acute rheumatic heart disease	0.000	0.973	0.026
I01.2 Acute rheumatic myocarditis	0.000	0.973	0.026
I01.1 Acute rheumatic endocarditis	0.000	0.973	0.026
I01.0 Acute rheumatic pericarditis	0.000	0.973	0.026
I02.9 Rheumatic chorea without heart involvement	0.000	0.973	0.026
I02.0 Rheumatic chorea with heart involvement	0.000	0.973	0.026
M23.43 Loose body in knee-Med lig/oth men	0.027	0.973	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.026	0.973	0.000
I31.8 Other specified diseases of pericardium	0.000	0.973	0.026
I31.2 Haemopericardium, not elsewhere classified	0.000	0.973	0.026
I31.1 Chronic constrictive pericarditis	0.000	0.973	0.026
I31.0 Chronic adhesive pericarditis	0.000	0.973	0.026
M25.2 Flail joint	0.026	0.974	0.000
M25.1 Fistula of joint	0.026	0.974	0.000
M25.0 Haemarthrosis	0.026	0.974	0.000
M24.29 Disorder of ligament (Site unspecified)	0.026	0.974	0.000
M24.28 Disorder of ligament (Other)	0.026	0.974	0.000
M24.26 Disorder of ligament (Lower leg)	0.026	0.974	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.026	0.974	0.000
M24.24 Disorder of ligament (Hand)	0.026	0.974	0.000
M24.22 Disorder of ligament (Upper arm)	0.026	0.974	0.000
M24.21 Disorder of ligament (Shoulder region)	0.026	0.974	0.000
M24.20 Disorder of ligament (Multiple sites)	0.026	0.974	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.026	0.974	0.000
I09 Other rheumatic heart diseases	0.000	0.974	0.026
I06 Rheumatic aortic valve diseases	0.000	0.974	0.026
M30.8 Other conditions related to polyarteritis nodosa	0.026	0.974	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.026	0.974	0.000
M30.2 Juvenile polyarteritis	0.026	0.974	0.000
M30.0 Polyarteritis nodosa	0.026	0.974	0.000
M24.09 Loose body in joint (Site unspecified)	0.025	0.974	0.000
M24.08 Loose body in joint (Other)	0.025	0.974	0.000
M24.06 Loose body in joint-Lower leg	0.025	0.974	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.025	0.974	0.000
M24.04 Loose body in joint (Hand)	0.025	0.974	0.000
M24.03 Loose body in joint (Forearm)	0.025	0.974	0.000
M24.01 Loose body in joint (Shoulder region)	0.025	0.974	0.000
M24.00 Loose body in joint (Multiple sites)	0.025	0.974	0.000
M21.2 Flexion deformity	0.025	0.974	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.025	0.975	0.000
M35.0 Sicca syndrome [Sjogren]	0.025	0.975	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.975	0.025
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.025	0.975	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.025	0.975	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.025	0.975	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.025	0.975	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.025	0.975	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.025	0.975	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.025	0.975	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.025	0.975	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.025	0.975	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.025	0.975	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.025	0.975	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.025	0.975	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.025	0.975	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.025	0.975	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.025	0.975	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.025	0.975	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.025	0.975	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.025	0.975	0.000
M21.4 Flat foot [pes planus] (acquired)	0.025	0.975	0.000
M24.02 Loose body in joint (Upper arm)	0.025	0.975	0.000
M25.9 Joint disorder, unspecified	0.025	0.975	0.000
M25.54 Pain in joint (Hand)	0.025	0.975	0.000
M25.34 Other instability of joint (Hand)	0.025	0.975	0.000
I27.0 Primary pulmonary hypertension	0.000	0.975	0.025
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.024	0.975	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.024	0.975	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.024	0.975	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.024	0.975	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.024	0.975	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.024	0.975	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.024	0.975	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.024	0.975	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.024	0.975	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.024	0.975	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.024	0.975	0.000
M24.68 Ankylosis of joint (Other)	0.024	0.975	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.024	0.975	0.000
M24.66 Ankylosis of joint (Lower leg)	0.024	0.975	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.024	0.975	0.000
M24.64 Ankylosis of joint (Hand)	0.024	0.975	0.000
M24.63 Ankylosis of joint (Forearm)	0.024	0.975	0.000
M24.62 Ankylosis of joint (Upper arm)	0.024	0.975	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.024	0.975	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.024	0.975	0.000
M24.79 Protrusio acetabuli-Site unspec	0.024	0.975	0.000
M24.78 Protrusio acetabuli-Other	0.024	0.975	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.024	0.975	0.000
M24.76 Protrusio acetabuli-Lower leg	0.024	0.975	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.024	0.975	0.000
M24.74 Protrusio acetabuli-Hand	0.024	0.975	0.000
M24.73 Protrusio acetabuli-Forearm	0.024	0.975	0.000
M24.72 Protrusio acetabuli-Upper arm	0.024	0.975	0.000
M24.71 Protrusio acetabuli-Shldr region	0.024	0.975	0.000
M24.70 Protrusio acetabuli-Mult sites	0.024	0.975	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.024	0.975	0.000
M24.98 Joint derangement, unspecified (Other)	0.024	0.975	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.024	0.975	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.024	0.975	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.024	0.975	0.000
M24.94 Joint derangement, unspecified (Hand)	0.024	0.975	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.024	0.975	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.024	0.975	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.024	0.975	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.024	0.975	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.976	0.024
M23.47 Loose body in knee-Capsular lig	0.024	0.976	0.000
M23.46 Loose body in knee-O/unsp lat men	0.024	0.976	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.024	0.976	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.024	0.976	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.024	0.976	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.024	0.976	0.000
M23.40 Loose body in knee-Mult sites	0.024	0.976	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.976	0.023
I10-I15 Hypertensive diseases	0.000	0.976	0.024
I27.8 Other specified pulmonary heart diseases	0.000	0.976	0.023
I27.1 Kyphoscoliotic heart disease	0.000	0.976	0.023
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.023	0.976	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.024	0.976	0.000
M21.6 Other acquired deformities of ankle and foot	0.023	0.976	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.023	0.976	0.000
M32.8 Other forms of systemic lupus erythematosus	0.023	0.976	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.023	0.976	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.023	0.976	0.000
M33.9 Dermatopolymyositis, unspecified	0.023	0.976	0.000
M33.2 Polymyositis	0.023	0.976	0.000
M33.1 Other dermatomyositis	0.023	0.976	0.000
M33.0 Juvenile dermatomyositis	0.023	0.976	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.023	0.976	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.023	0.976	0.000
M36.3 Arthropathy in other blood disorders	0.023	0.976	0.000
M36.2 Haemophilic arthropathy	0.023	0.976	0.000
M36.1 Arthropathy in neoplastic disease	0.023	0.976	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.023	0.976	0.000
M21.9 Acquired deformity of limb, unspecified	0.023	0.976	0.000
M21.8 Other specified acquired deformities of limbs	0.023	0.976	0.000
M21.7 Unequal limb length (acquired)	0.023	0.976	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.023	0.976	0.000
I60-I69 Cerebrovascular diseases	0.000	0.976	0.024
M25.89 Other specified joint disorders (Site unspecified)	0.023	0.977	0.000
M25.88 Other specified joint disorders (Other)	0.023	0.977	0.000
M25.82 Other specified joint disorders (Upper arm)	0.023	0.977	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.023	0.977	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.023	0.977	0.000
M34.8 Other forms of systemic sclerosis	0.023	0.977	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.023	0.977	0.000
M34.1 CR(E)ST syndrome	0.023	0.977	0.000
M34.0 Progressive systemic sclerosis	0.023	0.977	0.000
M25.51 Pain in joint (Shoulder region)	0.023	0.977	0.000
M34.9 Systemic sclerosis, unspecified	0.023	0.977	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.023	0.977	0.000
M25.31 Other instability of joint (Shoulder region)	0.023	0.977	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.977	0.023
M25.52 Pain in joint (Upper arm)	0.023	0.977	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.977	0.023
I47 Paroxysmal tachycardia	0.000	0.977	0.023
I34.1 Mitral (valve) prolapse	0.000	0.977	0.023
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.022	0.977	0.000
M25.84 Other specified joint disorders (Hand)	0.022	0.977	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.977	0.022
I28.8 Other specified diseases of pulmonary vessels	0.000	0.977	0.022
I28.1 Aneurysm of pulmonary artery	0.000	0.977	0.022
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.977	0.022
M21.1 Varus deformity, not elsewhere classified	0.022	0.978	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.022	0.978	0.000
M25.78 Osteophyte (Other)	0.022	0.978	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.022	0.978	0.000
M21.3 Wrist or foot drop (acquired)	0.022	0.978	0.000
M25.58 Pain in joint (Other)	0.022	0.978	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.021	0.978	0.000
M25.74 Osteophyte (Hand)	0.022	0.978	0.000
M21.0 Valgus deformity, not elsewhere classified	0.021	0.978	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.021	0.978	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.021	0.978	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.021	0.978	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.021	0.978	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.021	0.978	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.021	0.978	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.021	0.978	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.021	0.978	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.021	0.979	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.021	0.979	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.021	0.979	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.021	0.979	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.021	0.979	0.000
M25.39 Other instability of joint (Site unspecified)	0.021	0.979	0.000
M25.38 Other instability of joint (Other)	0.021	0.979	0.000
M25.36 Other instability of joint (Lower leg)	0.021	0.979	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.021	0.979	0.000
M25.33 Other instability of joint (Forearm)	0.021	0.979	0.000
M25.32 Other instability of joint (Upper arm)	0.021	0.979	0.000
M25.30 Other instability of joint (Multiple sites)	0.021	0.979	0.000
I08 Multiple valve diseases	0.000	0.979	0.021
M25.77 Osteophyte (Ankle and foot)	0.021	0.979	0.000
M25.79 Osteophyte (Site unspecified)	0.021	0.979	0.000
M25.73 Osteophyte (Forearm)	0.021	0.979	0.000
M25.72 Osteophyte (Upper arm)	0.021	0.979	0.000
M25.70 Osteophyte (Multiple sites)	0.021	0.979	0.000
M21.24 Flexion deformity (Hand)	0.020	0.979	0.000
M31.6 Other giant cell arteritis	0.020	0.980	0.000
M25.59 Pain in joint (Site unspecified)	0.020	0.980	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.980	0.020
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.980	0.020
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.980	0.020

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations