TreeWAS – Variant ID: rs72932726

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.981	0.019
M06.9 Rheumatoid arthritis, unspecified	0.000	0.983	0.017
K51.8 Other ulcerative colitis	0.000	0.984	0.016
K51 Ulcerative colitis	0.000	0.984	0.016
K51.2 Ulcerative (chronic) proctitis	0.000	0.985	0.015
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.985	0.015
H61.0 Perichondritis of external ear	0.015	0.985	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.985	0.015
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.986	0.014
O42.9 Premature rupture of membranes, unspecified	0.000	0.986	0.014
K51.9 Ulcerative colitis, unspecified	0.000	0.986	0.014
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.986	0.014
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.986	0.014
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.987	0.013
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.987	0.013
H61 Other disorders of external ear	0.013	0.987	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.987	0.013
H61.8 Other specified disorders of external ear	0.013	0.987	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.987	0.013
M06 Other rheumatoid arthritis	0.000	0.988	0.012
Z57 Occupational exposure to risk-factors	0.012	0.988	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.988	0.012
O42 Premature rupture of membranes	0.000	0.988	0.012
Z57.2 Occupational exposure to dust	0.012	0.988	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.988	0.012
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.988	0.012
Z57.3 Occupational exposure to other air contaminants	0.012	0.988	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.011	0.989	0.000
H61.2 Impacted cerumen	0.011	0.989	0.000
K50.1 Crohn's disease of large intestine	0.000	0.989	0.011
K50-K52 Noninfective enteritis and colitis	0.000	0.989	0.011
K51.5 Mucosal proctocolitis	0.000	0.989	0.011
K50.9 Crohn's disease, unspecified	0.000	0.989	0.011
H61.1 Non-infective disorders of pinna	0.011	0.989	0.000
Z63 Other problems related to primary support group, including family circumstances	0.011	0.989	0.000
K50.8 Other Crohn's disease	0.000	0.990	0.010
Z60 Problems related to social environment	0.010	0.990	0.000
M06.3 Rheumatoid nodule	0.000	0.990	0.010
Z63.0 Problems in relationship with spouse or partner	0.010	0.990	0.000
Y84.6 Urinary catheterisation	0.010	0.990	0.000
Y57 Other and unspecified drugs and medicaments	0.010	0.990	0.000
Z60.2 Living alone	0.010	0.990	0.000
Y57.5 X-ray contrast media	0.010	0.990	0.000
Z56 Problems related to employment and unemployment	0.010	0.990	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.010	0.990	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.990	0.010
M06.0 Seronegative rheumatoid arthritis	0.000	0.990	0.009
H61.9 Disorder of external ear, unspecified	0.009	0.990	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.010	0.990	0.000
K51.4 Pseudopolyposis of colon	0.000	0.991	0.009
Y44 Agents primarily affecting blood constituents	0.009	0.991	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.991	0.009
M06.2 Rheumatoid bursitis	0.000	0.991	0.009
M06.1 Adult-onset Still's disease	0.000	0.991	0.009
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.991	0.009
Z57.9 Occupational exposure to unspecified risk-factor	0.009	0.991	0.000
Z57.8 Occupational exposure to other risk-factors	0.009	0.991	0.000
Z57.7 Occupational exposure to vibration	0.009	0.991	0.000
Z57.6 Occupational exposure to extreme temperature	0.009	0.991	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.009	0.991	0.000
Z57.1 Occupational exposure to radiation	0.009	0.991	0.000
Z57.0 Occupational exposure to noise	0.009	0.991	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.991	0.009
Z59 Problems related to housing and economic circumstances	0.009	0.991	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.991	0.009
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.991	0.009
Y44.2 Anticoagulants	0.009	0.991	0.000
K50.0 Crohn's disease of small intestine	0.000	0.991	0.009
K01.1 Impacted teeth	0.000	0.991	0.009
Y57.6 Other diagnostic agents	0.009	0.991	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.009	0.991	0.000
Y84.4 Aspiration of fluid	0.009	0.991	0.000
Z56.6 Other physical and mental strain related to work	0.008	0.991	0.000
X60-X84 Intentional self-harm	0.009	0.991	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.008	0.992	0.000
Z65 Problems related to other psychosocial circumstances	0.008	0.992	0.000
Z64 Problems related to certain psychosocial circumstances	0.008	0.992	0.000
Z62 Other problems related to upbringing	0.008	0.992	0.000
Z61 Problems related to negative life events in childhood	0.008	0.992	0.000
Z55 Problems related to education and literacy	0.008	0.992	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.008	0.992	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
Z91.5 Personal history of self-harm	0.008	0.992	0.000
Z63.8 Other specified problems related to primary support group	0.008	0.992	0.000
Z58 Problems related to physical environment	0.008	0.992	0.000
Z63.7 Other stressful life events affecting family and household	0.008	0.992	0.000
I73.0 Raynaud's syndrome	0.008	0.992	0.000
Y57.9 Drug or medicament, unspecified	0.008	0.992	0.000
O02.1 Missed abortion	0.008	0.992	0.000
Z63.5 Disruption of family by separation and divorce	0.008	0.992	0.000
Y48 Anaesthetics and therapeutic gases	0.008	0.992	0.000
Z63.9 Problem related to primary support group, unspecified	0.008	0.992	0.000
Z63.6 Dependent relative needing care at home	0.008	0.992	0.000
Z63.3 Absence of family member	0.008	0.992	0.000
Z63.2 Inadequate family support	0.008	0.992	0.000
Z63.1 Problems in relationship with parents and in-laws	0.008	0.992	0.000
Chapter XX External causes of morbidity and mortality	0.008	0.992	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.992	0.008
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.992	0.008
Y40 Systemic antibiotics	0.008	0.992	0.000
Z63.4 Disappearance and death of family member	0.008	0.992	0.000
Z60.9 Problem related to social environment, unspecified	0.008	0.992	0.000
Z60.8 Other problems related to social environment	0.008	0.992	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.008	0.992	0.000
Z60.4 Social exclusion and rejection	0.008	0.992	0.000
Z60.3 Acculturation difficulty	0.008	0.992	0.000
Z60.1 Atypical parenting situation	0.008	0.992	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.008	0.992	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.008	0.992	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.992	0.007
M06.38 Rheumatoid nodule (Other)	0.000	0.992	0.007
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.992	0.007
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.992	0.007
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.992	0.007
M06.33 Rheumatoid nodule (Forearm)	0.000	0.992	0.007
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.992	0.007
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.992	0.007
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.992	0.007
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.992	0.008
Y54.8 Agents affecting uric acid metabolism	0.008	0.992	0.000
Y84.2 Radiological procedure and radiotherapy	0.008	0.992	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.007	0.992	0.000
Y57.8 Other drugs and medicaments	0.007	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.007	0.992	0.000
Y57.4 Pharmaceutical excipients	0.007	0.992	0.000
Y57.3 Alcohol deterrents	0.007	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.007	0.992	0.000
Y57.1 Lipotropic drugs	0.007	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.007	0.992	0.000
R05 Cough	0.008	0.992	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.007	0.993	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.007	0.993	0.000
X78 Intentional self-harm by sharp object	0.007	0.993	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.007	0.993	0.000
Y84.9 Medical procedure, unspecified	0.007	0.993	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.007	0.993	0.000
Z56.7 Other and unspecified problems related to employment	0.007	0.993	0.000
Z56.5 Uncongenial work	0.007	0.993	0.000
Z56.4 Discord with boss and workmates	0.007	0.993	0.000
Z56.3 Stressful work schedule	0.007	0.993	0.000
Z56.2 Threat of job loss	0.007	0.993	0.000
Z56.1 Change of job	0.007	0.993	0.000
Z56.0 Unemployment, unspecified	0.007	0.993	0.000
Y59 Other and unspecified vaccines and biological substances	0.007	0.993	0.000
Y58 Bacterial vaccines	0.007	0.993	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.007	0.993	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.007	0.993	0.000
V01-V09 Pedestrian injured in transport accident	0.007	0.993	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.993	0.007
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.993	0.007
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.993	0.007
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.993	0.007
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.993	0.007
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.993	0.007
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.993	0.007
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.993	0.007
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.993	0.007
Y44.5 Thrombolytic drugs	0.007	0.993	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.993	0.007
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.993	0.007
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.993	0.007
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.993	0.007
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.993	0.007
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.993	0.007
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.993	0.007
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.993	0.007
Y41.5 Antiviral drugs	0.007	0.993	0.000
Y84.7 Blood-sampling	0.007	0.993	0.000
Y84.5 Insertion of gastric or duodenal sound	0.007	0.993	0.000
Y84.3 Shock therapy	0.007	0.993	0.000
Z59.0 Homelessness	0.007	0.993	0.000
Y41.0 Sulphonamides	0.007	0.993	0.000
Y84.0 Cardiac catheterisation	0.007	0.993	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.007	0.993	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.007	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.007	0.993	0.000
Y44.7 Plasma substitutes	0.007	0.993	0.000
Y44.6 Natural blood and blood products	0.007	0.993	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.007	0.993	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.007	0.993	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.007	0.993	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.007	0.993	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.993	0.007
M06.18 Adult-onset Still's disease (Other)	0.000	0.993	0.007
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.993	0.007
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.993	0.007
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.993	0.007
M06.14 Adult-onset Still's disease (Hand)	0.000	0.993	0.007
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.993	0.007
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.993	0.007
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.993	0.007
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.993	0.007
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.993	0.007
M06.28 Rheumatoid bursitis (Other)	0.000	0.993	0.007
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.993	0.007
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.993	0.007
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.993	0.007
M06.24 Rheumatoid bursitis (Hand)	0.000	0.993	0.007
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.993	0.007
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.993	0.007
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.993	0.007
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.993	0.007
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.993	0.007
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.993	0.007
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.993	0.007
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.993	0.007
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.993	0.007
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.993	0.007
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.993	0.007
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.993	0.007
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.993	0.007
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.993	0.007
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.993	0.007
Z59.8 Other problems relating to housing and economic circumstances	0.007	0.993	0.000
Y84.8 Other medical procedures	0.007	0.993	0.000
V95-V97 Air and space transport accidents	0.007	0.993	0.000
Y54.3 Benzothiadiazine derivatives	0.007	0.993	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.006	0.993	0.000
Z59.7 Insufficient social insurance and welfare support	0.006	0.993	0.000
Z59.6 Low income	0.006	0.993	0.000
Z59.5 Extreme poverty	0.006	0.993	0.000
Z59.4 Lack of adequate food	0.006	0.993	0.000
Z59.3 Problems related to living in residential institution	0.006	0.993	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.006	0.993	0.000
Z59.1 Inadequate housing	0.006	0.993	0.000
H61.3 Acquired stenosis of external ear canal	0.006	0.993	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.993	0.000
Y41.4 Anthelminthics	0.006	0.993	0.000
Y41.3 Other antiprotozoal drugs	0.006	0.993	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.993	0.000
Y41.1 Antimycobacterial drugs	0.006	0.993	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.993	0.006
X62.9 Unspecified place	0.006	0.993	0.000
X78.0 Home	0.006	0.993	0.000
Y48.4 Anaesthetic, unspecified	0.006	0.994	0.000
Y84.1 Kidney dialysis	0.006	0.994	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.006	0.994	0.000
Y48.3 Local anaesthetics	0.006	0.994	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.006	0.994	0.000
X84 Intentional self-harm by unspecified means	0.006	0.994	0.000
X83 Intentional self-harm by other specified means	0.006	0.994	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.006	0.994	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.006	0.994	0.000
X80 Intentional self-harm by jumping from a high place	0.006	0.994	0.000
X79 Intentional self-harm by blunt object	0.006	0.994	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.006	0.994	0.000
X76 Intentional self-harm by smoke, fire and flames	0.006	0.994	0.000
X75 Intentional self-harm by explosive material	0.006	0.994	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.006	0.994	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.006	0.994	0.000
X72 Intentional self-harm by handgun discharge	0.006	0.994	0.000
X71 Intentional self-harm by drowning and submersion	0.006	0.994	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.006	0.994	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.006	0.994	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.006	0.994	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
Y40.8 Other systemic antibiotics	0.006	0.994	0.000
O02 Other abnormal products of conception	0.006	0.994	0.000
Y54.4 Loop [high-ceiling] diuretics	0.006	0.994	0.000
X20-X29 Contact with venomous animals and plants	0.006	0.994	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.006	0.994	0.000
Z55.8 Other problems relating to education and literacy	0.006	0.994	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.006	0.994	0.000
Z55.3 Underachievement in school	0.006	0.994	0.000
Z55.2 Failed examinations	0.006	0.994	0.000
Z55.1 Schooling unavailable and unattainable	0.006	0.994	0.000
Z55.0 Illiteracy and low-level literacy	0.006	0.994	0.000
Z61.9 Negative life events in childhood, unspecified	0.006	0.994	0.000
Z61.8 Other negative life events in childhood	0.006	0.994	0.000
Z61.7 Personal frightening experience in childhood	0.006	0.994	0.000
Z61.6 Problems related to alleged physical abuse of child	0.006	0.994	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.006	0.994	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.006	0.994	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.006	0.994	0.000
Z61.2 Altered pattern of family relationships in childhood	0.006	0.994	0.000
Z61.1 Removal from home in childhood	0.006	0.994	0.000
Z61.0 Loss of love relationship in childhood	0.006	0.994	0.000
Z62.9 Problem related to upbringing, unspecified	0.006	0.994	0.000
Z62.8 Other specified problems related to upbringing	0.006	0.994	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.006	0.994	0.000
Z62.5 Other problems related to neglect in upbringing	0.006	0.994	0.000
Z62.4 Emotional neglect of child	0.006	0.994	0.000
Z62.3 Hostility towards and scapegoating of child	0.006	0.994	0.000
Z62.2 Institutional upbringing	0.006	0.994	0.000
Z62.1 Parental overprotection	0.006	0.994	0.000
Z62.0 Inadequate parental supervision and control	0.006	0.994	0.000
Z64.4 Discord with counsellors	0.006	0.994	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.006	0.994	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.006	0.994	0.000
Z64.1 Problems related to multiparity	0.006	0.994	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.006	0.994	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.006	0.994	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.006	0.994	0.000
Z65.4 Victim of crime and terrorism	0.006	0.994	0.000
Z65.3 Problems related to other legal circumstances	0.006	0.994	0.000
Z65.2 Problems related to release from prison	0.006	0.994	0.000
Z65.1 Imprisonment and other incarceration	0.006	0.994	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.006	0.994	0.000
Y54.9 Mineral salts, not elsewhere classified	0.006	0.994	0.000
Y54.7 Agents affecting calcification	0.006	0.994	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.006	0.994	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.006	0.994	0.000
Y54.0 Mineralocorticoids	0.006	0.994	0.000
Z64.0 Problems related to unwanted pregnancy	0.006	0.994	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
Y51.0 Anticholinesterase agents	0.006	0.994	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
W50-W64 Exposure to animate mechanical forces	0.006	0.994	0.000
V98-V99 Other and unspecified transport accidents	0.006	0.994	0.000
Y40.0 Penicillins	0.006	0.994	0.000
Y00-Y09 Assault	0.006	0.994	0.000
X69.9 Unspecified place	0.006	0.994	0.000
Y53.4 Other laxatives	0.006	0.994	0.000
Z58.9 Problem related to physical environment, unspecified	0.006	0.994	0.000
Z58.8 Other problems related to physical environment	0.006	0.994	0.000
Z58.7 Exposure to tobacco smoke	0.006	0.994	0.000
Z58.6 Inadequate drinking-water supply	0.006	0.994	0.000
Z58.5 Exposure to other pollution	0.006	0.994	0.000
Z58.4 Exposure to radiation	0.006	0.994	0.000
Z58.3 Exposure to soil pollution	0.006	0.994	0.000
Z58.2 Exposure to water pollution	0.006	0.994	0.000
Z58.0 Exposure to noise	0.006	0.994	0.000
V40-V49 Car occupant injured in transport accident	0.006	0.994	0.000
X50-X57 Overexertion, travel and privation	0.006	0.994	0.000
X10-X19 Contact with heat and hot substances	0.006	0.994	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.006	0.994	0.000
Y48.5 Therapeutic gases	0.006	0.994	0.000
Y48.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
Y48.1 Parenteral anaesthetics	0.006	0.994	0.000
Y48.0 Inhaled anaesthetics	0.006	0.994	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.006	0.994	0.000
V01 Pedestrian injured in collision with pedal cycle	0.006	0.994	0.000
Y35-Y36 Legal intervention and operations of war	0.006	0.994	0.000
Y10-Y34 Event of undetermined intent	0.006	0.994	0.000
X85-X99 Assault	0.006	0.994	0.000
X30-X39 Exposure to forces of nature	0.006	0.994	0.000
X00-X09 Exposure to smoke, fire and flames	0.006	0.994	0.000
W75-W84 Other accidental threats to breathing	0.006	0.994	0.000
W65-W74 Accidental drowning and submersion	0.006	0.994	0.000
V90-V94 Water transport accidents	0.006	0.994	0.000
V70-V79 Bus occupant injured in transport accident	0.006	0.994	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.006	0.994	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.006	0.994	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.006	0.994	0.000
M07.3 Other psoriatic arthropathies	0.000	0.994	0.006
Y53.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.006	0.994	0.000
V09 Pedestrian injured in other and unspecified transport accidents	0.006	0.994	0.000
V04 Pedestrian injured in collision with heavy transport vehicle or bus	0.006	0.994	0.000
Z58.1 Exposure to air pollution	0.006	0.994	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.006	0.994	0.000
Y40.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
Y40.6 Rifamycins	0.006	0.994	0.000
Y40.5 Aminoglycosides	0.006	0.994	0.000
Y40.4 Tetracyclines	0.006	0.994	0.000
Y40.3 Macrolides	0.006	0.994	0.000
Y40.2 Chloramphenicol group	0.006	0.994	0.000
V96 Accident to nonpowered aircraft causing injury to occupant	0.006	0.994	0.000
Y46.4 Iminostilbenes	0.006	0.994	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
V80-V89 Other land transport accidents	0.006	0.994	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y53.7 Emetics	0.006	0.994	0.000
Y53.6 Antidiarrhoeal drugs	0.006	0.994	0.000
Y53.5 Digestants	0.006	0.994	0.000
Y53.3 Saline and osmotic laxatives	0.006	0.994	0.000
Y53.2 Stimulant laxatives	0.006	0.994	0.000
Y53.0 Histamine H2-receptor antagonists	0.006	0.994	0.000
Y49.2 Other and unspecified antidepressants	0.006	0.994	0.000
V20-V29 Motorcycle rider injured in transport accident	0.006	0.994	0.000
X65.8 Other specified place	0.006	0.994	0.000
X69.0 Home	0.006	0.994	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.006	0.994	0.000
Y54.5 Other diuretics	0.006	0.994	0.000
Y49.5 Other antipsychotics and neuroleptics	0.005	0.994	0.000
X63.0 Home	0.006	0.994	0.000
X68.9 Unspecified place	0.005	0.994	0.000
Y46.8 Antispasticity drugs	0.005	0.994	0.000
Y46.7 Anti-Parkinsonism drugs	0.005	0.994	0.000
Y46.6 Other and unspecified antiepileptics	0.005	0.994	0.000
Y46.5 Valproic acid	0.005	0.994	0.000
Y46.3 Deoxybarbiturates	0.005	0.994	0.000
Y46.2 Hydantoin derivatives	0.005	0.994	0.000
Y46.1 Oxazolidinediones	0.005	0.994	0.000
Y46.0 Succinimides	0.005	0.994	0.000
Y49.9 Psychotropic drug, unspecified	0.005	0.994	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.005	0.994	0.000
Y49.7 Psychostimulants with abuse potential	0.005	0.994	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.005	0.994	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.994	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.994	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.994	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.005	0.994	0.000
Z91.2 Personal history of poor personal hygiene	0.006	0.994	0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.005	0.994	0.000
X62.0 Home	0.005	0.994	0.000
X62.8 Other specified place	0.005	0.994	0.000
X62.7 Farm	0.005	0.994	0.000
X62.6 Industrial and construction area	0.005	0.994	0.000
X62.5 Trade and service area	0.005	0.994	0.000
X62.4 Street and highway	0.005	0.994	0.000
X62.3 Sports and athletics area	0.005	0.994	0.000
X62.2 School, other institution and public administrative area	0.005	0.994	0.000
X62.1 Residential institution	0.005	0.994	0.000
X78.9 Unspecified place	0.005	0.994	0.000
X78.8 Other specified place	0.005	0.994	0.000
X78.7 Farm	0.005	0.994	0.000
X78.6 Industrial and construction area	0.005	0.994	0.000
X78.5 Trade and service area	0.005	0.994	0.000
X78.4 Street and highway	0.005	0.994	0.000
X78.3 Sports and athletics area	0.005	0.994	0.000
X78.2 School, other institution and public administrative area	0.005	0.994	0.000
X78.1 Residential institution	0.005	0.994	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.005	0.994	0.000
X69.8 Other specified place	0.005	0.995	0.000
X69.7 Farm	0.005	0.995	0.000
X69.6 Industrial and construction area	0.005	0.995	0.000
X69.5 Trade and service area	0.005	0.995	0.000
X69.4 Street and highway	0.005	0.995	0.000
X69.3 Sports and athletics area	0.005	0.995	0.000
X69.2 School, other institution and public administrative area	0.005	0.995	0.000
X69.1 Residential institution	0.005	0.995	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.005	0.995	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.005	0.995	0.000
Y47.4 Bromine compounds	0.005	0.995	0.000
Y47.3 Paraldehyde	0.005	0.995	0.000
Y47.2 Chloral derivatives	0.005	0.995	0.000
Y47.1 Benzodiazepines	0.005	0.995	0.000
Y47.0 Barbiturates, not elsewhere classified	0.005	0.995	0.000
Y50.9 Central nervous system stimulant, unspecified	0.005	0.995	0.000
Y50.8 Other central nervous system stimulants	0.005	0.995	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.005	0.995	0.000
Y50.1 Opioid receptor antagonists	0.005	0.995	0.000
Y50.0 Analeptics	0.005	0.995	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
Y55.5 Anticommon cold drugs	0.005	0.995	0.000
Y55.4 Expectorants	0.005	0.995	0.000
Y55.3 Antitussives	0.005	0.995	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
Y55.0 Oxytocic drugs	0.005	0.995	0.000
Y56.9 Topical agent, unspecified	0.005	0.995	0.000
Y56.8 Other topical agents	0.005	0.995	0.000
Y56.7 Dental drugs, topically applied	0.005	0.995	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
Y56.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
Y56.3 Emollients, demulcents and protectants	0.005	0.995	0.000
Y56.2 Local astringents and local detergents	0.005	0.995	0.000
Y56.1 Antipruritics	0.005	0.995	0.000
Y58.9 Other and unspecified bacterial vaccines	0.005	0.995	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.005	0.995	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.005	0.995	0.000
Y58.5 Diphtheria vaccine	0.005	0.995	0.000
Y58.4 Tetanus vaccine	0.005	0.995	0.000
Y58.3 Plague vaccine	0.005	0.995	0.000
Y58.2 Cholera vaccine	0.005	0.995	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.005	0.995	0.000
Y58.0 BCG vaccine	0.005	0.995	0.000
Y59.9 Vaccine or biological substance, unspecified	0.005	0.995	0.000
Y59.8 Other specified vaccines and biological substances	0.005	0.995	0.000
Y59.3 Immunoglobulin	0.005	0.995	0.000
Y59.2 Protozoal vaccines	0.005	0.995	0.000
Y59.1 Rickettsial vaccines	0.005	0.995	0.000
Y59.0 Viral vaccines	0.005	0.995	0.000
V06 Pedestrian injured in collision with other nonmotor vehicle	0.005	0.995	0.000
V05 Pedestrian injured in collision with railway train or railway vehicle	0.005	0.995	0.000
V03 Pedestrian injured in collision with car, pick-up truck or van	0.005	0.995	0.000
V02 Pedestrian injured in collision with two- or three-wheeled motor vehicle	0.005	0.995	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.995	0.005
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.005	0.995	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.005	0.995	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.005	0.995	0.000
V96.1 Hang-glider accident injuring occupant	0.005	0.995	0.000
X65.9 Unspecified place	0.005	0.995	0.000
X65.0 Home	0.005	0.995	0.000
X65.7 Farm	0.005	0.995	0.000
X65.6 Industrial and construction area	0.005	0.995	0.000
X65.5 Trade and service area	0.005	0.995	0.000
X65.4 Street and highway	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations