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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72977016
log Bayes Factor = 0.166281
Chromosome 3   position 140,370,012  (GRCh37) Explore rs72977016 on Ensembl!
Variant rs72977016 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.306 0.694 0.000
M54 Dorsalgia
0.305 0.695 0.000
M50-M54 Other dorsopathies
0.303 0.697 0.000
M54.9 Dorsalgia, unspecified
0.293 0.707 0.000
M80-M85 Disorders of bone density and structure
0.289 0.711 0.000
M54.5 Low back pain
0.289 0.711 0.000
M20-M25 Other joint disorders
0.284 0.716 0.000
M45-M49 Spondylopathies
0.282 0.718 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.281 0.719 0.000
M86-M90 Other osteopathies
0.279 0.721 0.000
M24 Other specific joint derangements
0.278 0.722 0.000
M54.56 Low back pain (Lumbar region)
0.274 0.726 0.000
M84 Disorders of continuity of bone
0.267 0.733 0.000
M05-M14 Inflammatory polyarthropathies
0.265 0.735 0.000
M47 Spondylosis
0.262 0.738 0.000
M60-M63 Disorders of muscles
0.256 0.744 0.000
M06 Other rheumatoid arthritis
0.254 0.746 0.000
M24.2 Disorder of ligament
0.253 0.747 0.000
M47.8 Other spondylosis
0.250 0.750 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.248 0.752 0.000
M25 Other joint disorders, not elsewhere classified
0.247 0.753 0.000
M54.57 Low back pain (Lumbosacral region)
0.246 0.754 0.000
M89 Other disorders of bone
0.246 0.754 0.000
M21 Other acquired deformities of limbs
0.241 0.759 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.240 0.760 0.000
M47.86 Other spondylosis (Lumbar region)
0.238 0.761 0.000
M53 Other dorsopathies, not elsewhere classified
0.238 0.762 0.000
M65-M68 Disorders of synovium and tendon
0.238 0.762 0.000
M06.9 Rheumatoid arthritis, unspecified
0.238 0.762 0.000
M81 Osteoporosis without pathological fracture
0.237 0.763 0.000
M87 Osteonecrosis
0.234 0.765 0.000
M54.2 Cervicalgia
0.234 0.766 0.000
M54.3 Sciatica
0.231 0.769 0.000
M91-M94 Chondropathies
0.230 0.770 0.000
M30 Polyarteritis nodosa and related conditions
0.229 0.771 0.000
M24.0 Loose body in joint
0.229 0.771 0.000
M48 Other spondylopathies
0.228 0.772 0.000
M31 Other necrotising vasculopathies
0.225 0.775 0.000
M85 Other disorders of bone density and structure
0.223 0.776 0.000
M54.50 Low back pain (Multiple sites in spine)
0.223 0.777 0.000
M34 Systemic sclerosis
0.220 0.780 0.000
M62 Other disorders of muscle
0.220 0.780 0.000
M24.1 Other articular cartilage disorders
0.220 0.780 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.220 0.780 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.219 0.781 0.000
M54.4 Lumbago with sciatica
0.219 0.781 0.000
M54.8 Other dorsalgia
0.219 0.781 0.000
M54.0 Panniculitis affecting regions of neck and back
0.219 0.781 0.000
M00-M03 Infectious arthropathies
0.219 0.781 0.000
M54.6 Pain in thoracic spine
0.218 0.782 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.218 0.782 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.218 0.782 0.000
M24.5 Contracture of joint
0.217 0.783 0.000
M90 Osteopathies in diseases classified elsewhere
0.216 0.784 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.216 0.784 0.000
M89.9 Disorder of bone, unspecified
0.215 0.785 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.213 0.787 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.212 0.788 0.000
M54.1 Radiculopathy
0.212 0.788 0.000
M25.5 Pain in joint
0.212 0.788 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.210 0.790 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.210 0.790 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.210 0.790 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.210 0.790 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.210 0.790 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.210 0.790 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.210 0.790 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.209 0.791 0.000
M83 Adult osteomalacia
0.207 0.793 0.000
M82 Osteoporosis in diseases classified elsewhere
0.207 0.793 0.000
M54.55 Low back pain (Thoracolumbar region)
0.207 0.793 0.000
M54.54 Low back pain-Thoracic
0.207 0.793 0.000
M54.53 Low back pain-Cervicothoracic
0.207 0.793 0.000
M54.52 Low back pain-Cervical
0.207 0.793 0.000
M54.51 Low back pain-Occipit-atl-axl
0.207 0.793 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.206 0.793 0.000
M21.0 Valgus deformity, not elsewhere classified
0.205 0.795 0.000
M24.24 Disorder of ligament (Hand)
0.205 0.795 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.205 0.795 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.204 0.796 0.000
M33 Dermatopolymyositis
0.204 0.796 0.000
M32 Systemic lupus erythematosus
0.204 0.796 0.000
M49 Spondylopathies in diseases classified elsewhere
0.202 0.797 0.000
M87.9 Osteonecrosis, unspecified
0.202 0.798 0.000
M84.0 Malunion of fracture
0.202 0.798 0.000
M05 Seropositive rheumatoid arthritis
0.202 0.798 0.000
M67 Other disorders of synovium and tendon
0.202 0.798 0.000
M06.0 Seronegative rheumatoid arthritis
0.202 0.798 0.000
M25.8 Other specified joint disorders
0.201 0.799 0.000
M80 Osteoporosis with pathological fracture
0.201 0.799 0.000
M24.9 Joint derangement, unspecified
0.199 0.800 0.000
M24.7 Protrusio acetabuli
0.199 0.800 0.000
M24.6 Ankylosis of joint
0.199 0.800 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.199 0.800 0.000
M06.4 Inflammatory polyarthropathy
0.199 0.801 0.000
M25.9 Joint disorder, unspecified
0.199 0.801 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.199 0.801 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.198 0.801 0.000
M81.4 Drug-induced osteoporosis
0.198 0.802 0.000
M86 Osteomyelitis
0.197 0.803 0.000
M45 Ankylosing spondylitis
0.197 0.803 0.000
M14 Arthropathies in other diseases classified elsewhere
0.197 0.803 0.000
M24.26 Disorder of ligament (Lower leg)
0.196 0.804 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.195 0.805 0.000
M25.51 Pain in joint (Shoulder region)
0.195 0.805 0.000
M47.9 Spondylosis, unspecified
0.194 0.806 0.000
M62.8 Other specified disorders of muscle
0.194 0.806 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.194 0.806 0.000
M46 Other inflammatory spondylopathies
0.192 0.808 0.000
M21.3 Wrist or foot drop (acquired)
0.192 0.808 0.000
M84.9 Disorder of continuity of bone, unspecified
0.191 0.809 0.000
M84.8 Other disorders of continuity of bone
0.191 0.809 0.000
M84.4 Pathological fracture, not elsewhere classified
0.191 0.809 0.000
M84.3 Stress fracture, not elsewhere classified
0.191 0.809 0.000
M84.2 Delayed union of fracture
0.191 0.809 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.191 0.809 0.000
M40-M43 Deforming dorsopathies
0.191 0.809 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.191 0.809 0.000
M11 Other crystal arthropathies
0.191 0.809 0.000
M89.8 Other specified disorders of bone
0.191 0.809 0.000
M51 Other intervertebral disk disorders
0.191 0.809 0.000
M12 Other specific arthropathies
0.190 0.809 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.190 0.809 0.000
M08 Juvenile arthritis
0.190 0.809 0.000
M50 Cervical disk disorders
0.190 0.810 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.190 0.810 0.000
M66 Spontaneous rupture of synovium and tendon
0.189 0.811 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.188 0.812 0.000
M47.1 Other spondylosis with myelopathy
0.187 0.813 0.000
M07 Psoriatic and enteropathic arthropathies
0.186 0.814 0.000
M25.3 Other instability of joint
0.186 0.814 0.000
M88 Paget's disease of bone [osteitis deformans]
0.185 0.815 0.000
M54.22 Cervicalgia (Cervical region)
0.184 0.816 0.000
M24.01 Loose body in joint (Shoulder region)
0.184 0.816 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.183 0.816 0.000
M61 Calcification and ossification of muscle
0.183 0.816 0.000
M60 Myositis
0.183 0.816 0.000
M06.8 Other specified rheumatoid arthritis
0.182 0.818 0.000
M06.3 Rheumatoid nodule
0.182 0.818 0.000
M06.2 Rheumatoid bursitis
0.182 0.818 0.000
M06.1 Adult-onset Still's disease
0.182 0.818 0.000
M24.29 Disorder of ligament (Site unspecified)
0.181 0.818 0.000
M24.28 Disorder of ligament (Other)
0.181 0.818 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.181 0.818 0.000
M24.23 Disorder of ligament (Forearm)
0.181 0.818 0.000
M24.22 Disorder of ligament (Upper arm)
0.181 0.818 0.000
M24.21 Disorder of ligament (Shoulder region)
0.181 0.818 0.000
M24.20 Disorder of ligament (Multiple sites)
0.181 0.818 0.000
M31.3 Wegener's granulomatosis
0.181 0.818 0.000
M24.07 Loose body in joint (Ankle and foot)
0.181 0.819 0.000
M92 Other juvenile osteochondrosis
0.181 0.819 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.180 0.820 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.179 0.820 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.179 0.821 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.179 0.821 0.000
M47.84 Other spondylosis (Thoracic region)
0.179 0.821 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.179 0.821 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.179 0.821 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.179 0.821 0.000
M85.0 Fibrous dysplasia (monostotic)
0.179 0.821 0.000
M47.89 Other spondylosis (Site unspecified)
0.178 0.822 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.178 0.822 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.178 0.822 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.178 0.822 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.178 0.822 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.178 0.822 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.178 0.822 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.177 0.823 0.000
M25.2 Flail joint
0.177 0.823 0.000
M25.1 Fistula of joint
0.177 0.823 0.000
M25.0 Haemarthrosis
0.177 0.823 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.177 0.823 0.000
M54.39 Sciatica (Site unspecified)
0.177 0.823 0.000
M48.0 Spinal stenosis
0.176 0.824 0.000
M89.6 Osteopathy after poliomyelitis
0.176 0.824 0.000
M89.5 Osteolysis
0.176 0.824 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.176 0.824 0.000
M89.3 Hypertrophy of bone
0.176 0.824 0.000
M89.2 Other disorders of bone development and growth
0.176 0.824 0.000
M89.1 Epiphyseal arrest
0.176 0.824 0.000
M89.0 Algoneurodystrophy
0.176 0.824 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.175 0.825 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.175 0.825 0.000
M34.9 Systemic sclerosis, unspecified
0.174 0.825 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.174 0.826 0.000
M89.98 Disorder of bone, unspecified (Other)
0.174 0.826 0.000
M67.8 Other specified disorders of synovium and tendon
0.174 0.826 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.174 0.826 0.000
M25.57 Pain in joint (Ankle and foot)
0.173 0.827 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.173 0.827 0.000
M21.9 Acquired deformity of limb, unspecified
0.173 0.827 0.000
M21.8 Other specified acquired deformities of limbs
0.173 0.827 0.000
M21.7 Unequal limb length (acquired)
0.173 0.827 0.000
M21.6 Other acquired deformities of ankle and foot
0.173 0.827 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.173 0.827 0.000
M21.4 Flat foot [pes planus] (acquired)
0.173 0.827 0.000
M21.2 Flexion deformity
0.173 0.827 0.000
M24.54 Contracture of joint (Hand)
0.173 0.827 0.000
M81.9 Osteoporosis, unspecified
0.172 0.828 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.172 0.828 0.000
M90.7 Fracture of bone in neoplastic disease
0.171 0.829 0.000
M53.9 Dorsopathy, unspecified
0.171 0.829 0.000
M53.8 Other specified dorsopathies
0.171 0.829 0.000
M53.2 Spinal instabilities
0.171 0.829 0.000
M53.1 Cervicobrachial syndrome
0.171 0.829 0.000
M53.0 Cervicocranial syndrome
0.171 0.829 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.171 0.829 0.000
M25.50 Pain in joint (Multiple sites)
0.171 0.829 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.170 0.829 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.170 0.829 0.000
M47.2 Other spondylosis with radiculopathy
0.170 0.829 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.170 0.830 0.000
M81.8 Other osteoporosis
0.170 0.830 0.000
M81.6 Localised osteoporosis [Lequesne]
0.170 0.830 0.000
M81.5 Idiopathic osteoporosis
0.170 0.830 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.170 0.830 0.000
M81.2 Osteoporosis of disuse
0.170 0.830 0.000
M81.1 Postoophorectomy osteoporosis
0.170 0.830 0.000
M81.0 Postmenopausal osteoporosis
0.170 0.830 0.000
M87.8 Other osteonecrosis
0.168 0.832 0.000
M87.3 Other secondary osteonecrosis
0.168 0.832 0.000
M87.2 Osteonecrosis due to previous trauma
0.168 0.832 0.000
M87.1 Osteonecrosis due to drugs
0.168 0.832 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.168 0.832 0.000
M54.29 Cervicalgia-Site unspe
0.168 0.832 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.168 0.832 0.000
M54.27 Cervicalgia-Lumbosacral
0.168 0.832 0.000
M54.26 Cervicalgia-Lumbar
0.168 0.832 0.000
M54.25 Cervicalgia-Thoracolumbar
0.168 0.832 0.000
M54.24 Cervicalgia-Thoracic
0.168 0.832 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.168 0.832 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.168 0.832 0.000
M54.20 Cervicalgia-Mult site
0.168 0.832 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.167 0.833 0.000
M25.4 Effusion of joint
0.167 0.833 0.000
M94 Other disorders of cartilage
0.167 0.833 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.167 0.833 0.000
M54.36 Sciatica (Lumbar region)
0.166 0.834 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.166 0.834 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.166 0.834 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.165 0.834 0.000
M54.37 Sciatica (Lumbosacral region)
0.165 0.834 0.000
M54.35 Sciatica (Thoracolumbar region)
0.165 0.834 0.000
M54.34 Sciatica-Thoracic
0.165 0.834 0.000
M54.33 Sciatica-Cervicothoracic
0.165 0.834 0.000
M54.32 Sciatica-Cervical
0.165 0.834 0.000
M54.31 Sciatica-Occipit-atl-axl
0.165 0.834 0.000
M54.30 Sciatica (Multiple sites in spine)
0.165 0.834 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.165 0.835 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.165 0.835 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.164 0.835 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.164 0.835 0.000
M30.2 Juvenile polyarteritis
0.164 0.835 0.000
M30.0 Polyarteritis nodosa
0.164 0.835 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.164 0.835 0.000
M24.09 Loose body in joint (Site unspecified)
0.164 0.836 0.000
M24.08 Loose body in joint (Other)
0.164 0.836 0.000
M24.06 Loose body in joint-Lower leg
0.164 0.836 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.164 0.836 0.000
M24.04 Loose body in joint (Hand)
0.164 0.836 0.000
M24.03 Loose body in joint (Forearm)
0.164 0.836 0.000
M24.00 Loose body in joint (Multiple sites)
0.164 0.836 0.000
M48.9 Spondylopathy, unspecified
0.164 0.836 0.000
M48.8 Other specified spondylopathies
0.164 0.836 0.000
M48.4 Fatigue fracture of vertebra
0.164 0.836 0.000
M48.3 Traumatic spondylopathy
0.164 0.836 0.000
M48.2 Kissing spine
0.164 0.836 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.164 0.836 0.000
M70-M79 Other soft tissue disorders
0.163 0.837 0.000
M25.84 Other specified joint disorders (Hand)
0.163 0.837 0.000
M31.6 Other giant cell arteritis
0.162 0.837 0.000
M31.9 Necrotising vasculopathy, unspecified
0.161 0.839 0.000
M31.8 Other specified necrotising vasculopathies
0.161 0.839 0.000
M31.7 Microscopic polyangiitis
0.161 0.839 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.161 0.839 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.161 0.839 0.000
M31.2 Lethal midline granuloma
0.161 0.839 0.000
M31.1 Thrombotic microangiopathy
0.161 0.839 0.000
M31.0 Hypersensitivity angiitis
0.161 0.839 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.161 0.839 0.000
M21.1 Varus deformity, not elsewhere classified
0.161 0.839 0.000
M24.02 Loose body in joint (Upper arm)
0.161 0.839 0.000
M85.9 Disorder of bone density and structure, unspecified
0.160 0.839 0.000
M85.6 Other cyst of bone
0.160 0.839 0.000
M85.5 Aneurysmal bone cyst
0.160 0.839 0.000
M85.4 Solitary bone cyst
0.160 0.839 0.000
M85.3 Osteitis condensans
0.160 0.839 0.000
M85.2 Hyperostosis of skull
0.160 0.839 0.000
M85.1 Skeletal fluorosis
0.160 0.839 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.160 0.840 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.159 0.841 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.159 0.841 0.000
M48.02 Spinal stenosis (Cervical region)
0.158 0.842 0.000
M34.8 Other forms of systemic sclerosis
0.158 0.842 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.158 0.842 0.000
M34.1 CR(E)ST syndrome
0.158 0.842 0.000
M34.0 Progressive systemic sclerosis
0.158 0.842 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.158 0.842 0.000
M85.8 Other specified disorders of bone density and structure
0.158 0.842 0.000
M62.9 Disorder of muscle, unspecified
0.158 0.842 0.000
M62.6 Muscle strain
0.158 0.842 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.158 0.842 0.000
M62.4 Contracture of muscle
0.158 0.842 0.000
M62.3 Immobility syndrome (paraplegic)
0.158 0.842 0.000
M62.2 Ischaemic infarction of muscle
0.158 0.842 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.158 0.842 0.000
M62.0 Diastasis of muscle
0.158 0.842 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.158 0.842 0.000
M24.18 Other articular cartilage disorders (Other)
0.158 0.842 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.158 0.842 0.000
M24.14 Other articular cartilage disorders (Hand)
0.158 0.842 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.158 0.842 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.158 0.842 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.158 0.842 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.158 0.842 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.158 0.842 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.158 0.842 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.158 0.842 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.158 0.842 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.158 0.842 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.158 0.842 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.158 0.842 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.157 0.843 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.157 0.843 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.157 0.843 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.157 0.843 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.157 0.843 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.157 0.843 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.157 0.843 0.000
M54.44 Lumbago with sciatica-Thoracic
0.157 0.843 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.157 0.843 0.000
M54.42 Lumbago with sciatica-Cervical
0.157 0.843 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.157 0.843 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.157 0.843 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.157 0.843 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.157 0.843 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.157 0.843 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.157 0.843 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.157 0.843 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.157 0.843 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.157 0.843 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.157 0.843 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.157 0.843 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.157 0.843 0.000
M54.89 Other dorsalgia (Site unspecified)
0.157 0.843 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.157 0.843 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.157 0.843 0.000
M54.86 Other dorsalgia (Lumbar region)
0.157 0.843 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.157 0.843 0.000
M54.84 Other dorsalgia (Thoracic region)
0.157 0.843 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.157 0.843 0.000
M54.82 Other dorsalgia (Cervical region)
0.157 0.843 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.157 0.843 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.157 0.843 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.157 0.843 0.000
M02 Reactive arthropathies
0.157 0.843 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.157 0.843 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.157 0.843 0.000
M54.69 Pain in thoracic spine-Site unspe
0.156 0.843 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.156 0.843 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.156 0.843 0.000
M54.66 Pain in thoracic spine-Lumbar
0.156 0.843 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.156 0.843 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.156 0.843 0.000
M54.62 Pain in thoracic spine-Cervical
0.156 0.843 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.156 0.843 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.156 0.843 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.156 0.844 0.000
M00 Pyogenic arthritis
0.156 0.844 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.156 0.844 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.156 0.844 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.156 0.844 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.156 0.844 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.156 0.844 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.156 0.844 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.156 0.844 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.156 0.844 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.156 0.844 0.000
M25.56 Pain in joint (Lower leg)
0.156 0.844 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.156 0.844 0.000
M93 Other osteochondropathies
0.156 0.844 0.000
M24.59 Contracture of joint (Site unspecified)
0.155 0.844 0.000
M24.58 Contracture of joint (Other)
0.155 0.844 0.000
M24.57 Contracture of joint (Ankle and foot)
0.155 0.844 0.000
M24.56 Contracture of joint (Lower leg)
0.155 0.844 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.155 0.844 0.000
M24.53 Contracture of joint (Forearm)
0.155 0.844 0.000
M24.52 Contracture of joint (Upper arm)
0.155 0.844 0.000
M24.51 Contracture of joint (Shoulder region)
0.155 0.844 0.000
M24.50 Contracture of joint (Multiple sites)
0.155 0.844 0.000
M51.4 Schmorl's nodes
0.155 0.845 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.155 0.845 0.000
M90.6 Osteitis deformans in neoplastic disease
0.155 0.845 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.155 0.845 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.155 0.845 0.000
M90.3 Osteonecrosis in caisson disease
0.155 0.845 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.155 0.845 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.155 0.845 0.000
M90.0 Tuberculosis of bone
0.155 0.845 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.154 0.845 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.154 0.845 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.154 0.845 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.154 0.845 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.154 0.845 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.154 0.845 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.154 0.845 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.153 0.847 0.000
M54.19 Radiculopathy (Site unspecified)
0.152 0.848 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.152 0.848 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.152 0.848 0.000
M54.14 Radiculopathy (Thoracic region)
0.152 0.848 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.152 0.848 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.152 0.848 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.152 0.848 0.000
M25.58 Pain in joint (Other)
0.152 0.848 0.000
M25.52 Pain in joint (Upper arm)
0.152 0.848 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.152 0.848 0.000
M50.2 Other cervical disk displacement
0.152 0.848 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.152 0.848 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.152 0.848 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.151 0.849 0.000
M50.1 Cervical disk disorder with radiculopathy
0.151 0.849 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.151 0.849 0.000
M66.0 Rupture of popliteal cyst
0.150 0.850 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.150 0.850 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.149 0.851 0.000
M82.1 Osteoporosis in endocrine disorders
0.149 0.851 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.149 0.851 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.149 0.851 0.000
M83.9 Adult osteomalacia, unspecified
0.149 0.851 0.000
M83.8 Other adult osteomalacia
0.149 0.851 0.000
M83.5 Other drug-induced osteomalacia in adults
0.149 0.851 0.000
M83.4 Aluminum bone disease
0.149 0.851 0.000
M83.3 Adult osteomalacia due to malnutrition
0.149 0.851 0.000
M83.2 Adult osteomalacia due to malabsorption
0.149 0.851 0.000
M83.1 Senile osteomalacia
0.149 0.851 0.000
M83.0 Puerperal osteomalacia
0.149 0.851 0.000
M67.1 Other contracture of tendon (sheath)
0.148 0.851 0.000
M10 Gout
0.148 0.852 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.147 0.852 0.000
M14.6 Neuropathic arthropathy
0.147 0.853 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.147 0.853 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.147 0.853 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.147 0.853 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.147 0.853 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.147 0.853 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.147 0.853 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.147 0.853 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.147 0.853 0.000
M25.59 Pain in joint (Site unspecified)
0.147 0.853 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.146 0.854 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.146 0.854 0.000
M32.8 Other forms of systemic lupus erythematosus
0.146 0.854 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.146 0.854 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.146 0.854 0.000
M33.9 Dermatopolymyositis, unspecified
0.146 0.854 0.000
M33.2 Polymyositis
0.146 0.854 0.000
M33.1 Other dermatomyositis
0.146 0.854 0.000
M33.0 Juvenile dermatomyositis
0.146 0.854 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.146 0.854 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.146 0.854 0.000
M36.3 Arthropathy in other blood disorders
0.146 0.854 0.000
M36.2 Haemophilic arthropathy
0.146 0.854 0.000
M36.1 Arthropathy in neoplastic disease
0.146 0.854 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.146 0.854 0.000
M92.6 Juvenile osteochondrosis of tarsus
0.146 0.854 0.000
M22 Disorders of patella
0.146 0.854 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.145 0.854 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.145 0.854 0.000
M49.4 Neuropathic spondylopathy
0.145 0.854 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.145 0.854 0.000
M49.2 Enterobacterial spondylitis
0.145 0.854 0.000
M49.1 Brucella spondylitis
0.145 0.854 0.000
M49.0 Tuberculosis of spine
0.145 0.854 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.145 0.855 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.145 0.855 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.145 0.855 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.145 0.855 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.145 0.855 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.145 0.855 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.145 0.855 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.145 0.855 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.145 0.855 0.000
M84.09 Malunion of fracture (Site unspecified)
0.145 0.855 0.000
M84.08 Malunion of fracture (Other)
0.145 0.855 0.000
M84.06 Malunion of fracture (Lower leg)
0.145 0.855 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.145 0.855 0.000
M84.04 Malunion of fracture (Hand)
0.145 0.855 0.000
M84.02 Malunion of fracture (Upper arm)
0.145 0.855 0.000
M84.01 Malunion of fracture (Shoulder region)
0.145 0.855 0.000
M84.00 Malunion of fracture (Multiple sites)
0.145 0.855 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.145 0.855 0.000
M05.8 Other seropositive rheumatoid arthritis
0.145 0.855 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.145 0.855 0.000
M05.2 Rheumatoid vasculitis
0.145 0.855 0.000
M05.1 Rheumatoid lung disease
0.145 0.855 0.000
M05.0 Felty's syndrome
0.145 0.855 0.000
M25.86 Other specified joint disorders (Lower leg)
0.145 0.855 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.145 0.855 0.000
M67.4 Ganglion
0.145 0.855 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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