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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73008782
log Bayes Factor = 8.48892
Chromosome 6   position 145,689,914  (GRCh37) Explore rs73008782 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E87.1 Hypo-osmolality and hyponatraemia
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I95 Hypotension
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.999 0.001 0.000
G56.2 Lesion of ulnar nerve
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
E86 Volume depletion
0.998 0.002 0.000
G56 Mononeuropathies of upper limb
0.998 0.002 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.998 0.002 0.000
I42 Cardiomyopathy
0.997 0.003 0.000
I51 Complications and ill-defined descriptions of heart disease
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.995 0.005 0.000
I95.9 Hypotension, unspecified
0.994 0.006 0.000
G40-G47 Episodic and paroxysmal disorders
0.994 0.006 0.000
G44 Other headache syndromes
0.990 0.010 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.986 0.014 0.000
I51.7 Cardiomegaly
0.986 0.014 0.000
F20 Schizophrenia
0.979 0.021 0.000
I42.9 Cardiomyopathy, unspecified
0.976 0.024 0.000
G44.2 Tension-type headache
0.972 0.028 0.000
I71 Aortic aneurysm and dissection
0.970 0.030 0.000
F30-F39 Mood [affective] disorders
0.968 0.032 0.000
Chapter XXII Codes for special purposes
0.966 0.034 0.000
I95.2 Hypotension due to drugs
0.966 0.034 0.000
I95.1 Orthostatic hypotension
0.964 0.036 0.000
I42.0 Dilated cardiomyopathy
0.960 0.040 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.957 0.043 0.000
F60-F69 Disorders of adult personality and behaviour
0.947 0.053 0.000
F20.0 Paranoid schizophrenia
0.945 0.055 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.944 0.056 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.942 0.058 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.941 0.059 0.000
I73 Other peripheral vascular diseases
0.940 0.060 0.000
F20.9 Schizophrenia, unspecified
0.937 0.063 0.000
E87.6 Hypokalaemia
0.936 0.064 0.000
Q60-Q64 Congenital malformations of the urinary system
0.927 0.073 0.000
Chapter XX External causes of morbidity and mortality
0.927 0.073 0.000
I73.9 Peripheral vascular disease, unspecified
0.925 0.075 0.000
Q18 Other congenital malformations of face and neck
0.906 0.094 0.000
E87.5 Hyperkalaemia
0.906 0.094 0.000
F60 Specific personality disorders
0.906 0.094 0.000
U51 Admission status on psychiatric patients
0.904 0.096 0.000
G56.8 Other mononeuropathies of upper limb
0.892 0.108 0.000
G44.0 Cluster headache syndrome
0.885 0.115 0.000
E87.0 Hyperosmolality and hypernatraemia
0.882 0.118 0.000
I74 Arterial embolism and thrombosis
0.878 0.122 0.000
I31 Other diseases of pericardium
0.873 0.127 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.868 0.132 0.000
I51.6 Cardiovascular disease, unspecified
0.862 0.138 0.000
F32 Depressive episode
0.860 0.140 0.000
G40 Epilepsy
0.855 0.145 0.000
U80 Agent resistant to penicillin and related antibiotics
0.854 0.146 0.000
Q12 Congenital lens malformations
0.851 0.149 0.000
G44.8 Other specified headache syndromes
0.847 0.153 0.000
E87.2 Acidosis
0.847 0.153 0.000
E50-E64 Other nutritional deficiencies
0.845 0.155 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.844 0.156 0.000
I51.8 Other ill-defined heart diseases
0.842 0.158 0.000
E20-E35 Disorders of other endocrine glands
0.841 0.159 0.000
Q61 Cystic kidney disease
0.840 0.160 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.834 0.165 0.000
F80-F89 Disorders of psychological development
0.834 0.166 0.000
G20-G26 Extrapyramidal and movement disorders
0.831 0.169 0.000
U51.1 Previously admitted to a psychiatric hospital of the provider
0.831 0.169 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.829 0.171 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.828 0.172 0.000
Chapter X Diseases of the respiratory system
0.822 0.178 0.000
I31.9 Disease of pericardium, unspecified
0.821 0.179 0.000
F32.1 Moderate depressive episode
0.821 0.179 0.000
G41 Status epilepticus
0.821 0.179 0.000
X60-X84 Intentional self-harm
0.818 0.182 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.817 0.183 0.000
I51.9 Heart disease, unspecified
0.809 0.191 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.809 0.191 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.807 0.193 0.000
G70-G73 Diseases of myoneural junction and muscle
0.807 0.193 0.000
E84 Cystic fibrosis
0.803 0.197 0.000
I42.8 Other cardiomyopathies
0.802 0.198 0.000
F30 Manic episode
0.802 0.198 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.797 0.203 0.000
F60.9 Personality disorder, unspecified
0.797 0.203 0.000
V90-V94 Water transport accidents
0.793 0.207 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.792 0.208 0.000
F39 Unspecified mood [affective] disorder
0.791 0.209 0.000
I42.6 Alcoholic cardiomyopathy
0.791 0.209 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.789 0.211 0.000
E55 Vitamin D deficiency
0.789 0.211 0.000
I44 Atrioventricular and left bundle-branch block
0.785 0.215 0.000
Q18.1 Preauricular sinus and cyst
0.784 0.216 0.000
J09-J18 Influenza and pneumonia
0.784 0.216 0.000
I70 Atherosclerosis
0.783 0.216 0.000
F33 Recurrent depressive disorder
0.781 0.219 0.000
I95.8 Other hypotension
0.780 0.220 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.778 0.222 0.000
J90-J94 Other diseases of pleura
0.776 0.224 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.775 0.225 0.000
Q12.0 Congenital cataract
0.774 0.226 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.766 0.234 0.000
I36 Nonrheumatic tricuspid valve disorders
0.764 0.236 0.000
I37 Pulmonary valve disorders
0.764 0.236 0.000
F25 Schizoaffective disorders
0.758 0.241 0.000
F60.3 Emotionally unstable personality disorder
0.758 0.242 0.000
Q61.3 Polycystic kidney, unspecified
0.758 0.242 0.000
I42.2 Other hypertrophic cardiomyopathy
0.752 0.248 0.000
I45 Other conduction disorders
0.752 0.248 0.000
Q60.0 Renal agenesis, unilateral
0.750 0.250 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.749 0.250 0.000
E55.9 Vitamin D deficiency, unspecified
0.748 0.252 0.000
F23 Acute and transient psychotic disorders
0.748 0.252 0.000
F34 Persistent mood [affective] disorders
0.745 0.255 0.000
E85 Amyloidosis
0.745 0.255 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.743 0.257 0.000
F70-F79 Mental retardation
0.743 0.257 0.000
I49 Other cardiac arrhythmias
0.741 0.259 0.000
G52 Disorders of other cranial nerves
0.739 0.261 0.000
I78 Diseases of capillaries
0.737 0.263 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.736 0.264 0.000
V40-V49 Car occupant injured in transport accident
0.735 0.265 0.000
G50 Disorders of trigeminal nerve
0.734 0.266 0.000
J60-J70 Lung diseases due to external agents
0.733 0.267 0.000
G56.3 Lesion of radial nerve
0.730 0.270 0.000
F69 Unspecified disorder of adult personality and behaviour
0.729 0.271 0.000
I51.0 Cardiac septal defect, acquired
0.727 0.273 0.000
U80.0 Penicillin resistant agent
0.725 0.275 0.000
W20-W49 Exposure to inanimate mechanical forces
0.721 0.279 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.721 0.279 0.000
W75-W84 Other accidental threats to breathing
0.721 0.279 0.000
I71.0 Dissection of aorta [any part]
0.720 0.280 0.000
Y00-Y09 Assault
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E87.4 Mixed disorder of acid-base balance
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
I74.5 Embolism and thrombosis of iliac artery
0.716 0.284 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.716 0.284 0.000
G56.4 Causalgia
0.716 0.284 0.000
Q25 Congenital malformations of great arteries
0.716 0.284 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.715 0.285 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.715 0.285 0.000
I42.5 Other restrictive cardiomyopathy
0.715 0.285 0.000
I42.4 Endocardial fibroelastosis
0.715 0.285 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
I51.5 Myocardial degeneration
0.714 0.286 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.714 0.286 0.000
F60.8 Other specific personality disorders
0.714 0.286 0.000
F31 Bipolar affective disorder
0.713 0.287 0.000
G44.3 Chronic posttraumatic headache
0.710 0.290 0.000
G44.1 Vascular headache, not elsewhere classified
0.710 0.290 0.000
F60.5 Anankastic personality disorder
0.708 0.292 0.000
F28 Other nonorganic psychotic disorders
0.707 0.293 0.000
F24 Induced delusional disorder
0.707 0.293 0.000
F21 Schizotypal disorder
0.707 0.293 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.707 0.293 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.293 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.293 0.000
F81 Specific developmental disorders of scholastic skills
0.707 0.293 0.000
E88 Other metabolic disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.703 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.703 0.297 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.702 0.298 0.000
F20.8 Other schizophrenia
0.702 0.298 0.000
F20.6 Simple schizophrenia
0.702 0.298 0.000
F20.5 Residual schizophrenia
0.702 0.298 0.000
F20.4 Postschizophrenic depression
0.702 0.298 0.000
F20.3 Undifferentiated schizophrenia
0.702 0.298 0.000
F20.2 Catatonic schizophrenia
0.702 0.298 0.000
F20.1 Hebephrenic schizophrenia
0.702 0.298 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.702 0.298 0.000
X78 Intentional self-harm by sharp object
0.701 0.299 0.000
G25 Other extrapyramidal and movement disorders
0.699 0.301 0.000
Q80-Q89 Other congenital malformations
0.699 0.301 0.000
J90 Pleural effusion, not elsewhere classified
0.698 0.302 0.000
V93 Accident on board watercraft without accident to watercraft, not causing drowning and submersion
0.698 0.302 0.000
J91 Pleural effusion in conditions classified elsewhere
0.698 0.302 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.698 0.302 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.697 0.303 0.000
E28 Ovarian dysfunction
0.697 0.303 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.696 0.304 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.696 0.304 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.696 0.304 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.696 0.304 0.000
I31.1 Chronic constrictive pericarditis
0.694 0.306 0.000
F38 Other mood [affective] disorders
0.694 0.306 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.693 0.307 0.000
Q60.2 Renal agenesis, unspecified
0.692 0.308 0.000
Q50-Q56 Congenital malformations of genital organs
0.692 0.308 0.000
J15.2 Pneumonia due to staphylococcus
0.690 0.310 0.000
E40-E46 Malnutrition
0.689 0.311 0.000
G45.3 Amaurosis fugax
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.688 0.312 0.000
G72 Other myopathies
0.688 0.312 0.000
E23 Hypofunction and other disorders of pituitary gland
0.688 0.312 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.687 0.313 0.000
Q17 Other congenital malformations of ear
0.686 0.313 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.686 0.313 0.000
Q15 Other congenital malformations of eye
0.686 0.313 0.000
Q14 Congenital malformations of posterior segment of eye
0.686 0.313 0.000
Q13 Congenital malformations of anterior segment of eye
0.686 0.313 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.686 0.313 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.686 0.313 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.685 0.315 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.684 0.316 0.000
I51.4 Myocarditis, unspecified
0.684 0.316 0.000
F29 Unspecified nonorganic psychosis
0.684 0.316 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.682 0.318 0.000
I49.5 Sick sinus syndrome
0.681 0.319 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.680 0.319 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.679 0.321 0.000
F68 Other disorders of adult personality and behaviour
0.679 0.321 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.679 0.321 0.000
F65 Disorders of sexual preference
0.679 0.321 0.000
F63 Habit and impulse disorders
0.679 0.321 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.679 0.321 0.000
F61 Mixed and other personality disorders
0.679 0.321 0.000
F60.6 Anxious [avoidant] personality disorder
0.678 0.322 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.676 0.324 0.000
U50 Level of care administered to neonates
0.675 0.325 0.000
U07 Emergency use of U07
0.675 0.325 0.000
U06 Emergency use of U06
0.675 0.325 0.000
U04 Severe acute respiratory syndrome [SARS]
0.675 0.325 0.000
U52 First in a series of a regular day/night admissions
0.675 0.325 0.000
F30.0 Hypomania
0.674 0.326 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.674 0.326 0.000
F60.7 Dependent personality disorder
0.674 0.326 0.000
J00-J06 Acute upper respiratory infections
0.672 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.671 0.329 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.670 0.329 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.670 0.330 0.000
G24 Dystonia
0.669 0.331 0.000
I44.1 Atrioventricular block, second degree
0.669 0.331 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.667 0.333 0.000
J14 Pneumonia due to Haemophilus influenzae
0.666 0.334 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.666 0.334 0.000
Q64 Other congenital malformations of urinary system
0.665 0.335 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.665 0.335 0.000
E87.3 Alkalosis
0.664 0.335 0.000
Y35-Y36 Legal intervention and operations of war
0.664 0.335 0.000
X85-X99 Assault
0.664 0.335 0.000
X30-X39 Exposure to forces of nature
0.664 0.335 0.000
X00-X09 Exposure to smoke, fire and flames
0.664 0.335 0.000
W65-W74 Accidental drowning and submersion
0.664 0.335 0.000
V98-V99 Other and unspecified transport accidents
0.664 0.335 0.000
V95-V97 Air and space transport accidents
0.664 0.335 0.000
V70-V79 Bus occupant injured in transport accident
0.664 0.335 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.664 0.335 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.664 0.335 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.664 0.335 0.000
J15.1 Pneumonia due to Pseudomonas
0.664 0.336 0.000
V01-V09 Pedestrian injured in transport accident
0.664 0.336 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.664 0.336 0.000
I45.3 Trifascicular block
0.664 0.336 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.663 0.337 0.000
E84.9 Cystic fibrosis, unspecified
0.662 0.338 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.659 0.341 0.000
G41.9 Status epilepticus, unspecified
0.658 0.342 0.000
W50-W64 Exposure to animate mechanical forces
0.658 0.342 0.000
E22 Hyperfunction of pituitary gland
0.658 0.342 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.657 0.342 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.656 0.344 0.000
E21.3 Hyperparathyroidism, unspecified
0.655 0.345 0.000
I44.2 Atrioventricular block, complete
0.654 0.346 0.000
X59 Exposure to unspecified factor
0.651 0.349 0.000
Q18.9 Congenital malformation of face and neck, unspecified
0.650 0.350 0.000
Q18.8 Other specified congenital malformations of face and neck
0.650 0.350 0.000
Q18.7 Microcheilia
0.650 0.350 0.000
Q18.6 Macrocheilia
0.650 0.350 0.000
Q18.5 Microstomia
0.650 0.350 0.000
Q18.4 Macrostomia
0.650 0.350 0.000
Q18.3 Webbing of neck
0.650 0.350 0.000
Q18.2 Other branchial cleft malformations
0.650 0.350 0.000
F60.4 Histrionic personality disorder
0.649 0.350 0.000
F60.2 Dissocial personality disorder
0.649 0.350 0.000
F60.1 Schizoid personality disorder
0.649 0.350 0.000
F60.0 Paranoid personality disorder
0.649 0.350 0.000
E20 Hypoparathyroidism
0.649 0.351 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.649 0.351 0.000
U51.2 Previously admitted to a psychiatric hospital of another provider
0.648 0.352 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.648 0.352 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.647 0.353 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.646 0.354 0.000
F64 Gender identity disorders
0.645 0.355 0.000
G41.0 Grand mal status epilepticus
0.643 0.357 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.643 0.357 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.643 0.357 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.641 0.359 0.000
E83 Disorders of mineral metabolism
0.641 0.359 0.000
X50-X57 Overexertion, travel and privation
0.639 0.361 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.638 0.362 0.000
X45 Accidental poisoning by and exposure to alcohol
0.637 0.363 0.000
Q61.2 Polycystic kidney, adult type
0.636 0.364 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.636 0.364 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.635 0.365 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.632 0.368 0.000
V20-V29 Motorcycle rider injured in transport accident
0.632 0.368 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.631 0.369 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.630 0.370 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.630 0.370 0.000
V93.1 Passenger ship
0.629 0.371 0.000
E28.2 Polycystic ovarian syndrome
0.629 0.371 0.000
E26 Hyperaldosteronism
0.628 0.372 0.000
G45.0 Vertebro-basilar artery syndrome
0.628 0.372 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.626 0.374 0.000
I31.8 Other specified diseases of pericardium
0.626 0.374 0.000
I31.2 Haemopericardium, not elsewhere classified
0.626 0.374 0.000
I31.0 Chronic adhesive pericarditis
0.626 0.374 0.000
Q61.5 Medullary cystic kidney
0.625 0.375 0.000
I78.1 Naevus, nonneoplastic
0.625 0.375 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.624 0.376 0.000
J12 Viral pneumonia, not elsewhere classified
0.622 0.377 0.000
I34 Nonrheumatic mitral valve disorders
0.622 0.378 0.000
J11 Influenza, virus not identified
0.620 0.380 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.620 0.380 0.000
I47 Paroxysmal tachycardia
0.618 0.382 0.000
X78.0 Home
0.616 0.384 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.615 0.384 0.000
F80 Specific developmental disorders of speech and language
0.615 0.385 0.000
F30.2 Mania with psychotic symptoms
0.613 0.387 0.000
E87.7 Fluid overload
0.613 0.387 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.613 0.387 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.613 0.387 0.000
I45.8 Other specified conduction disorders
0.611 0.389 0.000
Q12.9 Congenital lens malformation, unspecified
0.610 0.390 0.000
Q12.8 Other congenital lens malformations
0.610 0.390 0.000
Q12.4 Spherophakia
0.610 0.390 0.000
Q12.3 Congenital aphakia
0.610 0.390 0.000
Q12.2 Coloboma of lens
0.610 0.390 0.000
Q12.1 Congenital displaced lens
0.610 0.390 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.610 0.390 0.000
F32.8 Other depressive episodes
0.609 0.391 0.000
E24 Cushing's syndrome
0.609 0.391 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.609 0.391 0.000
Y00 Assault by blunt object
0.608 0.392 0.000
E73 Lactose intolerance
0.608 0.392 0.000
Q61.0 Congenital single renal cyst
0.608 0.392 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.606 0.394 0.000
E63 Other nutritional deficiencies
0.606 0.394 0.000
E56 Other vitamin deficiencies
0.606 0.394 0.000
E51 Thiamine deficiency
0.606 0.394 0.000
E50 Vitamin A deficiency
0.606 0.394 0.000
E60 Dietary zinc deficiency
0.606 0.394 0.000
E59 Dietary selenium deficiency
0.606 0.394 0.000
E58 Dietary calcium deficiency
0.606 0.394 0.000
E54 Ascorbic acid deficiency
0.606 0.394 0.000
E52 Niacin deficiency [pellagra]
0.606 0.394 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.606 0.394 0.000
I73.8 Other specified peripheral vascular diseases
0.606 0.394 0.000
Q60.6 Potter's syndrome
0.605 0.395 0.000
Q60.5 Renal hypoplasia, unspecified
0.605 0.395 0.000
Q60.4 Renal hypoplasia, bilateral
0.605 0.395 0.000
Q60.3 Renal hypoplasia, unilateral
0.605 0.395 0.000
Q60.1 Renal agenesis, bilateral
0.605 0.395 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.603 0.397 0.000
E32 Diseases of thymus
0.603 0.397 0.000
E31 Polyglandular dysfunction
0.603 0.397 0.000
E30 Disorders of puberty, not elsewhere classified
0.603 0.397 0.000
E25 Adrenogenital disorders
0.603 0.397 0.000
J06.9 Acute upper respiratory infection, unspecified
0.602 0.398 0.000
Q61.8 Other cystic kidney diseases
0.602 0.398 0.000
Q61.4 Renal dysplasia
0.602 0.398 0.000
Q61.1 Polycystic kidney, infantile type
0.602 0.398 0.000
I70.1 Atherosclerosis of renal artery
0.602 0.398 0.000
Q24 Other congenital malformations of heart
0.601 0.399 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.601 0.399 0.000
Q61.9 Cystic kidney disease, unspecified
0.600 0.400 0.000
F84 Pervasive developmental disorders
0.599 0.401 0.000
F89 Unspecified disorder of psychological development
0.598 0.402 0.000
F88 Other disorders of psychological development
0.598 0.402 0.000
F83 Mixed specific developmental disorders
0.598 0.402 0.000
F82 Specific developmental disorder of motor function
0.598 0.402 0.000
I77 Other disorders of arteries and arterioles
0.598 0.402 0.000
I44.6 Other and unspecified fascicular block
0.597 0.402 0.000
G23 Other degenerative diseases of basal ganglia
0.596 0.404 0.000
G21 Secondary Parkinsonism
0.596 0.404 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.596 0.404 0.000
G22 Parkinsonism in diseases classified elsewhere
0.596 0.404 0.000
I95.0 Idiopathic hypotension
0.596 0.404 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.596 0.404 0.000
I37.1 Pulmonary valve insufficiency
0.595 0.405 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.594 0.406 0.000
Q25.3 Stenosis of aorta
0.594 0.406 0.000
X48 Accidental poisoning by and exposure to pesticides
0.593 0.407 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.593 0.407 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.593 0.407 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.593 0.407 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.593 0.407 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.593 0.407 0.000
J17 Pneumonia in diseases classified elsewhere
0.590 0.409 0.000
E21.2 Other hyperparathyroidism
0.590 0.410 0.000
Y77.3 Surgical instruments, materials and devices (including sutures)
0.589 0.411 0.000
G41.8 Other status epilepticus
0.588 0.411 0.000
G41.2 Complex partial status epilepticus
0.588 0.411 0.000
G41.1 Petit mal status epilepticus
0.588 0.411 0.000
V80-V89 Other land transport accidents
0.588 0.412 0.000
G71 Primary disorders of muscles
0.588 0.412 0.000
Q23 Congenital malformations of aortic and mitral valves
0.588 0.412 0.000
G40.8 Other epilepsy
0.588 0.412 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.587 0.412 0.000
E85.9 Amyloidosis, unspecified
0.587 0.413 0.000
X84 Intentional self-harm by unspecified means
0.586 0.413 0.000
X83 Intentional self-harm by other specified means
0.586 0.413 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.586 0.413 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.586 0.413 0.000
X80 Intentional self-harm by jumping from a high place
0.586 0.413 0.000
X79 Intentional self-harm by blunt object
0.586 0.413 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.586 0.413 0.000
X76 Intentional self-harm by smoke, fire and flames
0.586 0.413 0.000
X75 Intentional self-harm by explosive material
0.586 0.413 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.586 0.413 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.586 0.413 0.000
X72 Intentional self-harm by handgun discharge
0.586 0.413 0.000
X71 Intentional self-harm by drowning and submersion
0.586 0.413 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.586 0.413 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.586 0.413 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.586 0.413 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.586 0.413 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.586 0.413 0.000
J93 Pneumothorax
0.586 0.414 0.000
I44.7 Left bundle-branch block, unspecified
0.585 0.415 0.000
F34.1 Dysthymia
0.585 0.415 0.000
I45.5 Other specified heart block
0.584 0.416 0.000
E85.3 Secondary systemic amyloidosis
0.583 0.417 0.000
X58 Exposure to other specified factors
0.583 0.417 0.000
V10-V19 Pedal cyclist injured in transport accident
0.582 0.418 0.000
E88.2 Lipomatosis, not elsewhere classified
0.581 0.419 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.580 0.420 0.000
I45.9 Conduction disorder, unspecified
0.580 0.420 0.000
Q27 Other congenital malformations of peripheral vascular system
0.579 0.421 0.000
Q26 Congenital malformations of great veins
0.579 0.421 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.579 0.421 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.579 0.421 0.000
J69 Pneumonitis due to solids and liquids
0.579 0.421 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.578 0.422 0.000
G72.8 Other specified myopathies
0.578 0.422 0.000
Q25.6 Stenosis of pulmonary artery
0.577 0.423 0.000
J92 Pleural plaque
0.577 0.423 0.000
E84.8 Cystic fibrosis with other manifestations
0.576 0.424 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.576 0.424 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.576 0.424 0.000
Q00-Q07 Congenital malformations of the nervous system
0.576 0.424 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.575 0.424 0.001
F25.1 Schizoaffective disorder, depressive type
0.575 0.424 0.000
F30.8 Other manic episodes
0.575 0.425 0.000
F30.1 Mania without psychotic symptoms
0.575 0.425 0.000
I33 Acute and subacute endocarditis
0.575 0.425 0.000
I49.0 Ventricular fibrillation and flutter
0.575 0.425 0.000
I50 Heart failure
0.574 0.426 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.572 0.427 0.000
W79 Inhalation and ingestion of food causing obstruction of respiratory tract
0.571 0.429 0.000
Q83 Congenital malformations of breast
0.569 0.431 0.000
V94 Other and unspecified water transport accidents
0.569 0.431 0.000
V92 Water-transport-related drowning and submersion without accident to watercraft
0.569 0.431 0.000
V91 Accident to watercraft causing other injury
0.569 0.431 0.000
V90 Accident to watercraft causing drowning and submersion
0.569 0.431 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.568 0.431 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.568 0.432 0.000
G24.9 Dystonia, unspecified
0.568 0.432 0.000
J15.9 Bacterial pneumonia, unspecified
0.568 0.432 0.000
E22.0 Acromegaly and pituitary gigantism
0.567 0.432 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.567 0.433 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.567 0.433 0.000
E55.0 Rickets, active
0.565 0.434 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.565 0.435 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.564 0.436 0.000
W22 Striking against or struck by other objects
0.563 0.437 0.000
F31.7 Bipolar affective disorder, currently in remission
0.563 0.437 0.000
I44.5 Left posterior fascicular block
0.563 0.437 0.000
I44.4 Left anterior fascicular block
0.563 0.437 0.000
W87 Exposure to unspecified electric current
0.562 0.437 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.562 0.438 0.000
J09 Influenza due to certain identified influenza virus
0.562 0.438 0.000
I70.9 Generalised and unspecified atherosclerosis
0.562 0.438 0.000
I70.8 Atherosclerosis of other arteries
0.562 0.438 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.562 0.438 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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