TreeWAS – Variant ID: rs73082331

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.001	0.999
Chapter XV Pregnancy, childbirth and the puerperium	0.997	0.003	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.005	0.995
I20-I25 Ischaemic heart diseases	0.000	0.005	0.995
O20-O29 Other maternal disorders predominantly related to pregnancy	0.993	0.007	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.991	0.009	0.000
O60-O75 Complications of labour and delivery	0.988	0.012	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.975	0.025	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.026	0.974
E78.5 Hyperlipidaemia, unspecified	0.000	0.027	0.973
I20 Angina pectoris	0.000	0.031	0.969
I21 Acute myocardial infarction	0.000	0.038	0.962
E78.0 Pure hypercholesterolaemia	0.000	0.038	0.962
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.959	0.041	0.000
I20.9 Angina pectoris, unspecified	0.000	0.042	0.958
E70-E90 Metabolic disorders	0.000	0.044	0.956
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.053	0.947
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.947	0.053	0.000
I10 Essential (primary) hypertension	0.000	0.055	0.945
O42 Premature rupture of membranes	0.943	0.057	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.063	0.937
O20 Haemorrhage in early pregnancy	0.937	0.063	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.066	0.934
E66 Obesity	0.000	0.066	0.934
E66.9 Obesity, unspecified	0.000	0.072	0.928
O36 Maternal care for other known or suspected foetal problems	0.918	0.082	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.916	0.084	0.000
E10-E14 Diabetes mellitus	0.000	0.094	0.906
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.902	0.098	0.000
O20.0 Threatened abortion	0.901	0.099	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.901	0.099	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.100	0.900
O42.9 Premature rupture of membranes, unspecified	0.896	0.104	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.895	0.105	0.000
I25.2 Old myocardial infarction	0.000	0.107	0.893
I22 Subsequent myocardial infarction	0.000	0.109	0.891
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.890	0.110	0.000
E66.8 Other obesity	0.000	0.116	0.884
O30 Multiple gestation	0.876	0.124	0.000
I10-I15 Hypertensive diseases	0.000	0.127	0.873
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.136	0.864
E86 Volume depletion	0.000	0.140	0.860
O14.9 Preeclampsia, unspecified	0.855	0.145	0.000
O21 Excessive vomiting in pregnancy	0.853	0.147	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.852	0.148	0.000
E11.2 With renal complications	0.000	0.149	0.851
O00-O08 Pregnancy with abortive outcome	0.839	0.161	0.000
O80-O84 Delivery	0.839	0.161	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.162	0.838
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.169	0.831
O23 Infections of genito-urinary tract in pregnancy	0.830	0.170	0.000
O28 Abnormal findings on antenatal screening of mother	0.828	0.172	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.826	0.174	0.000
I12 Hypertensive renal disease	0.000	0.177	0.823
O41 Other disorders of amniotic fluid and membranes	0.812	0.188	0.000
E83 Disorders of mineral metabolism	0.000	0.190	0.810
O63 Long labour	0.810	0.190	0.000
O62 Abnormalities of forces of labour	0.809	0.191	0.000
O72 Postpartum haemorrhage	0.803	0.197	0.000
E11.4 With neurological complications	0.000	0.203	0.797
O61 Failed induction of labour	0.796	0.204	0.000
O36.5 Maternal care for poor foetal growth	0.794	0.206	0.000
O30.0 Twin pregnancy	0.793	0.207	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.211	0.789
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.788	0.212	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.785	0.215	0.000
O03 Spontaneous abortion	0.784	0.216	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.783	0.217	0.000
O85-O92 Complications predominantly related to the puerperium	0.783	0.217	0.000
O34.4 Maternal care for other abnormalities of cervix	0.781	0.219	0.000
E78.4 Other hyperlipidaemia	0.000	0.220	0.780
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.221	0.779
O26.8 Other specified pregnancy-related conditions	0.778	0.222	0.000
O82 Single delivery by Caesarean section	0.775	0.225	0.000
E11.3 With ophthalmic complications	0.000	0.225	0.775
O74 Complications of anaesthesia during labour and delivery	0.769	0.231	0.000
O47 False labour	0.768	0.232	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.768	0.232	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.768	0.232	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.767	0.233	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.236	0.764
O33 Maternal care for known or suspected disproportion	0.761	0.239	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.240	0.760
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.760	0.240	0.000
O34.1 Maternal care for tumour of corpus uteri	0.753	0.247	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.753	0.247	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.248	0.752
O36.4 Maternal care for intra-uterine death	0.748	0.252	0.000
O20.8 Other haemorrhage in early pregnancy	0.748	0.252	0.000
I25.4 Coronary artery aneurysm	0.000	0.259	0.741
E11.6 With other specified complications	0.000	0.261	0.739
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.263	0.737
O66 Other obstructed labour	0.736	0.264	0.000
O22 Venous complications in pregnancy	0.736	0.264	0.000
E85 Amyloidosis	0.000	0.267	0.733
O14.1 Severe preeclampsia	0.725	0.274	0.000
E11.5 With peripheral circulatory complications	0.000	0.275	0.725
O72.2 Delayed and secondary postpartum haemorrhage	0.724	0.276	0.000
O82.0 Delivery by elective Caesarean section	0.722	0.278	0.000
O03.4 Incomplete, without complication	0.722	0.278	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.278	0.722
O71 Other obstetric trauma	0.721	0.279	0.000
E83.1 Disorders of iron metabolism	0.000	0.280	0.720
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.718	0.282	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.717	0.282	0.000
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
E13 Other specified diabetes mellitus	0.000	0.284	0.716
Chapter IX Diseases of the circulatory system	0.000	0.284	0.716
I23 Certain current complications following acute myocardial infarction	0.000	0.286	0.714
O29 Complications of anaesthesia during pregnancy	0.712	0.288	0.000
O25 Malnutrition in pregnancy	0.712	0.288	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.712	0.288	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.712	0.288	0.000
O26.2 Pregnancy care of habitual aborter	0.711	0.289	0.000
O31 Complications specific to multiple gestation	0.710	0.290	0.000
O63.9 Long labour, unspecified	0.710	0.290	0.000
O21.0 Mild hyperemesis gravidarum	0.708	0.292	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.708	0.292	0.000
O60 Preterm delivery	0.708	0.292	0.000
O73 Retained placenta and membranes, without haemorrhage	0.703	0.296	0.000
E11.0 With coma	0.000	0.297	0.703
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.701	0.299	0.000
E78.6 Lipoprotein deficiency	0.000	0.302	0.698
E78.3 Hyperchylomicronaemia	0.000	0.302	0.698
E11.9 Without complications	0.000	0.307	0.693
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.310	0.690
O23.4 Unspecified infection of urinary tract in pregnancy	0.690	0.310	0.000
O26.9 Pregnancy-related condition, unspecified	0.689	0.311	0.000
O62.2 Other uterine inertia	0.689	0.311	0.000
E00-E07 Disorders of thyroid gland	0.000	0.312	0.688
E84 Cystic fibrosis	0.000	0.314	0.686
E79 Disorders of purine and pyrimidine metabolism	0.000	0.314	0.686
E77 Disorders of glycoprotein metabolism	0.000	0.314	0.686
E76 Disorders of glycosaminoglycan metabolism	0.000	0.314	0.686
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.314	0.686
E72 Other disorders of amino-acid metabolism	0.000	0.314	0.686
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.314	0.686
E70 Disorders of aromatic amino-acid metabolism	0.000	0.314	0.686
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.314	0.686
I12.9 Hypertensive renal disease without renal failure	0.000	0.315	0.685
E78.1 Pure hyperglyceridaemia	0.000	0.317	0.683
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.318	0.682
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.319	0.681
O41.0 Oligohydramnios	0.681	0.319	0.000
O15 Eclampsia	0.679	0.321	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.679	0.321	0.000
O40 Polyhydramnios	0.677	0.323	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.676	0.324	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.325	0.675
E74 Other disorders of carbohydrate metabolism	0.000	0.328	0.671
O34.8 Maternal care for other abnormalities of pelvic organs	0.671	0.329	0.000
E67 Other hyperalimentation	0.000	0.330	0.669
E68 Sequelae of hyperalimentation	0.000	0.330	0.669
E66.1 Drug-induced obesity	0.000	0.330	0.669
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.669	0.331	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.664	0.336	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.663	0.336	0.000
O24 Diabetes mellitus in pregnancy	0.662	0.338	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.661	0.339	0.000
O63.0 Prolonged first stage (of labour)	0.660	0.340	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.660	0.340	0.000
O61.0 Failed medical induction of labour	0.659	0.341	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.658	0.341	0.000
O36.2 Maternal care for hydrops foetalis	0.658	0.341	0.000
O36.1 Maternal care for other isoimmunisation	0.658	0.341	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.342	0.658
O26.5 Maternal hypotension syndrome	0.656	0.343	0.000
O26.4 Herpes gestationis	0.656	0.343	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.656	0.343	0.000
O26.1 Low weight gain in pregnancy	0.656	0.343	0.000
O26.0 Excessive weight gain in pregnancy	0.656	0.343	0.000
I20.0 Unstable angina	0.000	0.350	0.650
E12 Malnutrition-related diabetes mellitus	0.000	0.350	0.650
E66.0 Obesity due to excess calories	0.000	0.351	0.649
E89.0 Postprocedural hypothyroidism	0.000	0.351	0.649
O21.8 Other vomiting complicating pregnancy	0.649	0.351	0.000
O14.0 Moderate preeclampsia	0.647	0.353	0.000
O14.2 HELLP syndrome	0.646	0.353	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.646	0.354	0.000
O34.6 Maternal care for abnormality of vagina	0.646	0.354	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.646	0.354	0.000
O34.0 Maternal care for congenital malformation of uterus	0.646	0.354	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.646	0.354	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.646	0.354	0.000
E11.7 With multiple complications	0.000	0.354	0.646
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.356	0.644
O12.1 Gestational proteinuria	0.643	0.357	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.642	0.358	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.642	0.358	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.642	0.358	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.642	0.358	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.642	0.358	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.642	0.358	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.642	0.358	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.358	0.642
O45 Premature separation of placenta [abruptio placentae]	0.641	0.358	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.359	0.641
O81 Single delivery by forceps and vacuum extractor	0.639	0.361	0.000
O90 Complications of the puerperium, not elsewhere classified	0.639	0.361	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.363	0.637
E04 Other non-toxic goitre	0.000	0.363	0.637
O30.9 Multiple gestation, unspecified	0.628	0.372	0.000
O30.8 Other multiple gestation	0.628	0.372	0.000
O30.2 Quadruplet pregnancy	0.628	0.372	0.000
O30.1 Triplet pregnancy	0.628	0.372	0.000
I13 Hypertensive heart and renal disease	0.000	0.374	0.626
O34.3 Maternal care for cervical incompetence	0.626	0.374	0.000
E73 Lactose intolerance	0.000	0.374	0.625
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.624	0.376	0.000
O36.9 Maternal care for foetal problem, unspecified	0.622	0.378	0.000
O36.8 Maternal care for other specified foetal problems	0.620	0.380	0.000
O12.2 Gestational oedema with proteinuria	0.617	0.382	0.000
O44 Placenta praevia	0.617	0.383	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.614	0.386	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.613	0.387	0.000
O21.2 Late vomiting of pregnancy	0.612	0.388	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.612	0.388	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.611	0.388	0.000
I20.8 Other forms of angina pectoris	0.000	0.389	0.611
O47.1 False labour at or after 37 completed weeks of gestation	0.609	0.391	0.000
E11.1 With ketoacidosis	0.000	0.391	0.609
O72.1 Other immediate postpartum haemorrhage	0.602	0.398	0.000
O07 Failed attempted abortion	0.602	0.398	0.000
O06 Unspecified abortion	0.602	0.398	0.000
O05 Other abortion	0.602	0.398	0.000
O01 Hydatidiform mole	0.602	0.398	0.000
O84 Multiple delivery	0.601	0.399	0.000
O83 Other assisted single delivery	0.601	0.399	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.401	0.599
O89 Complications of anaesthesia during the puerperium	0.596	0.404	0.000
O33.9 Maternal care for disproportion, unspecified	0.596	0.404	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.595	0.404	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.595	0.405	0.000
O23.2 Infections of urethra in pregnancy	0.595	0.405	0.000
O23.1 Infections of bladder in pregnancy	0.595	0.405	0.000
O23.0 Infections of kidney in pregnancy	0.595	0.405	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.594	0.406	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.594	0.406	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.594	0.406	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.594	0.406	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.594	0.406	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.594	0.406	0.000
O03.9 Complete or unspecified, without complication	0.589	0.411	0.000
O62.0 Primary inadequate contractions	0.589	0.411	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.589	0.411	0.000
O43 Placental disorders	0.588	0.412	0.000
O86 Other puerperal infections	0.587	0.413	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.587	0.413	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.416	0.584
O82.1 Delivery by emergency Caesarean section	0.584	0.416	0.000
E85.9 Amyloidosis, unspecified	0.000	0.416	0.584
O69 Labour and delivery complicated by umbilical cord complications	0.583	0.417	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.582	0.418	0.000
O41.1 Infection of amniotic sac and membranes	0.582	0.418	0.000
O23.5 Infections of the genital tract in pregnancy	0.581	0.418	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.419	0.581
E83.8 Other disorders of mineral metabolism	0.000	0.419	0.581
E83.2 Disorders of zinc metabolism	0.000	0.419	0.581
E83.0 Disorders of copper metabolism	0.000	0.419	0.581
O63.2 Delayed delivery of second twin, triplet, etc.	0.581	0.419	0.000
E13.9 Without complications	0.000	0.420	0.580
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.580	0.420	0.000
O62.9 Abnormality of forces of labour, unspecified	0.580	0.420	0.000
O62.8 Other abnormalities of forces of labour	0.580	0.420	0.000
O72.3 Postpartum coagulation defects	0.576	0.424	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.575	0.425	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.574	0.426	0.000
O61.9 Failed induction of labour, unspecified	0.571	0.429	0.000
O61.8 Other failed induction of labour	0.571	0.429	0.000
O61.1 Failed instrumental induction of labour	0.571	0.429	0.000
I15 Secondary hypertension	0.000	0.430	0.570
O47.0 False labour before 37 completed weeks of gestation	0.567	0.433	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.434	0.566
O62.3 Precipitate labour	0.565	0.435	0.000
O75.9 Complication of labour and delivery, unspecified	0.563	0.437	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.563	0.437	0.000
O75.4 Other complications of obstetric surgery and procedures	0.563	0.437	0.000
O75.3 Other infection during labour	0.563	0.437	0.000
O75.1 Shock during or following labour and delivery	0.563	0.437	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.562	0.438	0.000
O03.7 Complete or unspecified, complicated by embolism	0.562	0.438	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.562	0.438	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.562	0.438	0.000
O03.3 Incomplete, with other and unspecified complications	0.562	0.438	0.000
O03.2 Incomplete, complicated by embolism	0.562	0.438	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.562	0.438	0.000
O62.1 Secondary uterine inertia	0.562	0.438	0.000
O91 Infections of breast associated with childbirth	0.561	0.439	0.000
O88 Obstetric embolism	0.561	0.439	0.000
O71.8 Other specified obstetric trauma	0.561	0.439	0.000
O82.9 Delivery by Caesarean section, unspecified	0.560	0.440	0.000
I25.3 Aneurysm of heart	0.000	0.441	0.559
O82.8 Other single delivery by Caesarean section	0.556	0.444	0.000
O82.2 Delivery by Caesarean hysterectomy	0.556	0.444	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.553	0.447	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.552	0.448	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.552	0.448	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.552	0.448	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.552	0.448	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.552	0.448	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.552	0.448	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.552	0.448	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.552	0.448	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.552	0.448	0.000
O75.8 Other specified complications of labour and delivery	0.551	0.448	0.000
E06 Thyroiditis	0.000	0.454	0.546
O33.8 Maternal care for disproportion of other origin	0.545	0.454	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.545	0.454	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.545	0.454	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.545	0.454	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.545	0.454	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.545	0.454	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.545	0.454	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.545	0.454	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.545	0.454	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.455	0.545
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.455	0.545
E89.5 Postprocedural testicular hypofunction	0.000	0.455	0.545
E89.4 Postprocedural ovarian failure	0.000	0.455	0.545
E89.1 Postprocedural hypoinsulinaemia	0.000	0.455	0.545
O71.7 Obstetric haematoma of pelvis	0.542	0.458	0.000
O02 Other abnormal products of conception	0.540	0.460	0.000
I11 Hypertensive heart disease	0.000	0.460	0.540
O04 Medical abortion	0.539	0.461	0.000
E14 Unspecified diabetes mellitus	0.000	0.464	0.536
O47.9 False labour, unspecified	0.533	0.467	0.000
O66.9 Obstructed labour, unspecified	0.528	0.472	0.000
O66.8 Other specified obstructed labour	0.528	0.472	0.000
O66.4 Failed trial of labour, unspecified	0.528	0.472	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.528	0.472	0.000
O66.2 Obstructed labour due to unusually large foetus	0.528	0.472	0.000
O66.1 Obstructed labour due to locked twins	0.528	0.472	0.000
O22.9 Venous complication in pregnancy, unspecified	0.528	0.472	0.000
O22.8 Other venous complications in pregnancy	0.528	0.472	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.528	0.472	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.528	0.472	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.528	0.472	0.000
O22.1 Genital varices in pregnancy	0.528	0.472	0.000
O22.4 Haemorrhoids in pregnancy	0.526	0.474	0.000
O85 Puerperal sepsis	0.525	0.474	0.000
E85.8 Other amyloidosis	0.000	0.474	0.525
E85.3 Secondary systemic amyloidosis	0.000	0.474	0.525
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.474	0.525
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.474	0.525
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.474	0.525
O20.9 Haemorrhage in early pregnancy, unspecified	0.522	0.478	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.481	0.519
O75.0 Maternal distress during labour and delivery	0.519	0.481	0.000
O21.9 Vomiting of pregnancy, unspecified	0.518	0.482	0.000
O71.9 Obstetric trauma, unspecified	0.517	0.483	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.517	0.483	0.000
O71.5 Other obstetric injury to pelvic organs	0.517	0.483	0.000
O71.3 Obstetric laceration of cervix	0.517	0.483	0.000
O71.2 Postpartum inversion of uterus	0.517	0.483	0.000
O71.1 Rupture of uterus during labour	0.517	0.483	0.000
O71.0 Rupture of uterus before onset of labour	0.517	0.483	0.000
O90.9 Complication of the puerperium, unspecified	0.517	0.483	0.000
O73.0 Retained placenta, without haemorrhage	0.516	0.484	0.000
O00 Ectopic pregnancy	0.515	0.485	0.000
E11.8 With unspecified complications	0.000	0.486	0.514
E13.8 With unspecified complications	0.000	0.486	0.514
E13.7 With multiple complications	0.000	0.486	0.514
E13.6 With other specified complications	0.000	0.486	0.514
E13.5 With peripheral circulatory complications	0.000	0.486	0.514
E13.4 With neurological complications	0.000	0.486	0.514
E13.3 With ophthalmic complications	0.000	0.486	0.514
E13.2 With renal complications	0.000	0.486	0.514
E13.1 With ketoacidosis	0.000	0.486	0.514
E13.0 With coma	0.000	0.486	0.514
I23.8 Other current complications following acute myocardial infarction	0.000	0.487	0.513
O64 Obstructed labour due to malposition and malpresentation of foetus	0.512	0.487	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.488	0.512
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.488	0.512
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.488	0.512
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.488	0.512
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.488	0.512
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.488	0.512
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.488	0.512
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.510	0.489	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.510	0.489	0.000
O29.6 Failed or difficult intubation during pregnancy	0.510	0.489	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.510	0.489	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.510	0.489	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.510	0.489	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.510	0.489	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.510	0.489	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.510	0.489	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.510	0.490	0.000
O97 Death from sequelae of direct obstetric causes	0.510	0.490	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.510	0.490	0.000
O95 Obstetric death of unspecified cause	0.510	0.490	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.510	0.490	0.000
E85.4 Organ-limited amyloidosis	0.000	0.490	0.510
O31.8 Other complications specific to multiple gestation	0.509	0.490	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.509	0.490	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.509	0.490	0.000
O31.0 Papyraceous foetus	0.509	0.490	0.000
O60.3 Preterm delivery without spontaneous labour	0.508	0.492	0.000
O60.2 Preterm spontaneous labour with term delivery	0.508	0.492	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.508	0.492	0.000
O60.0 Preterm labour without delivery	0.508	0.492	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.508	0.492	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.508	0.492	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.508	0.492	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.508	0.492	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.508	0.492	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.508	0.492	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.508	0.492	0.000
O65.0 Obstructed labour due to deformed pelvis	0.508	0.492	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.507	0.493	0.000
O36.6 Maternal care for excessive foetal growth	0.503	0.497	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.499	0.501
O81.4 Vacuum extractor delivery	0.500	0.500	0.000
E40-E46 Malnutrition	0.001	0.500	0.499
E65 Localised adiposity	0.000	0.501	0.499
O66.0 Obstructed labour due to shoulder dystocia	0.496	0.504	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.493	0.506	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.506	0.493
E00 Congenital iodine-deficiency syndrome	0.000	0.506	0.493
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.508	0.492
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.508	0.492
E70.3 Albinism	0.000	0.508	0.492
E70.2 Disorders of tyrosine metabolism	0.000	0.508	0.492
E70.1 Other hyperphenylalaninaemias	0.000	0.508	0.492
E70.0 Classical phenylketonuria	0.000	0.508	0.492
E71.3 Disorders of fatty-acid metabolism	0.000	0.508	0.492
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.508	0.492
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.508	0.492
E71.0 Maple-syrup-urine disease	0.000	0.508	0.492
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.508	0.492
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.508	0.492
E72.5 Disorders of glycine metabolism	0.000	0.508	0.492
E72.4 Disorders of ornithine metabolism	0.000	0.508	0.492
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.508	0.492
E72.2 Disorders of urea cycle metabolism	0.000	0.508	0.492
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.508	0.492
E72.0 Disorders of amino-acid transport	0.000	0.508	0.492
E75.6 Lipid storage disorder, unspecified	0.000	0.508	0.492
E75.5 Other lipid storage disorders	0.000	0.508	0.492
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.508	0.492
E75.3 Sphingolipidosis, unspecified	0.000	0.508	0.492
E75.2 Other sphingolipidosis	0.000	0.508	0.492
E75.1 Other gangliosidosis	0.000	0.508	0.492
E75.0 GM2 gangliosidosis	0.000	0.508	0.492
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.508	0.492
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.508	0.492
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.508	0.492
E76.2 Other mucopolysaccharidoses	0.000	0.508	0.492
E76.1 Mucopolysaccharidosis, type II	0.000	0.508	0.492
E76.0 Mucopolysaccharidosis, type I	0.000	0.508	0.492
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.508	0.492
E77.8 Other disorders of glycoprotein metabolism	0.000	0.508	0.492
E77.1 Defects in glycoprotein degradation	0.000	0.508	0.492
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.508	0.492
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.508	0.492
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.508	0.492
E79.1 Lesch-Nyhan syndrome	0.000	0.508	0.492
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.508	0.492
E84.9 Cystic fibrosis, unspecified	0.000	0.508	0.492
E84.8 Cystic fibrosis with other manifestations	0.000	0.508	0.492
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.508	0.492
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.508	0.492
O46 Antepartum haemorrhage, not elsewhere classified	0.491	0.508	0.000
E50-E64 Other nutritional deficiencies	0.000	0.509	0.491
O87 Venous complications in the puerperium	0.489	0.511	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.511	0.489
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.511	0.489
E80.6 Other disorders of bilirubin metabolism	0.000	0.511	0.489
E80.5 Crigler-Najjar syndrome	0.000	0.511	0.489
E80.3 Defects of catalase and peroxydase	0.000	0.511	0.489
E80.2 Other porphyria	0.000	0.511	0.489
E80.1 Porphyria cutanea tarda	0.000	0.511	0.489
E80.0 Hereditary erythropoietic porphyria	0.000	0.511	0.489
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.487	0.513	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.513	0.487
O15.9 Eclampsia, unspecified as to time period	0.487	0.513	0.000
O15.2 Eclampsia in the puerperium	0.487	0.513	0.000
O15.1 Eclampsia in labour	0.487	0.513	0.000
O15.0 Eclampsia in pregnancy	0.487	0.513	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.486	0.514	0.000
E80.4 Gilbert's syndrome	0.000	0.515	0.485
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.518	0.481
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.518	0.481
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.518	0.481
E74.2 Disorders of galactose metabolism	0.000	0.518	0.481
E74.1 Disorders of fructose metabolism	0.000	0.518	0.481
E74.0 Glycogen storage disease	0.000	0.518	0.481
E67.8 Other specified hyperalimentation	0.000	0.520	0.480
E67.3 Hypervitaminosis D	0.000	0.520	0.480
E67.2 Megavitamin-B6 syndrome	0.000	0.520	0.480
E67.1 Hypercarotenaemia	0.000	0.520	0.480
E67.0 Hypervitaminosis A	0.000	0.520	0.480
O67.8 Other intrapartum haemorrhage	0.480	0.520	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.480	0.520	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.475	0.525	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.475	0.525	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.475	0.525	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.475	0.525	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.533	0.467

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations