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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74335365
log Bayes Factor = 9.03859
Chromosome 14   position 60,693,242  (GRCh37) Explore rs74335365 on Ensembl!
Variant rs74335365 is part of Cluster X0221

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I50.0 Congestive heart failure
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
0.999 0.001 0.000
J33 Nasal polyp
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.990 0.010 0.000
I44 Atrioventricular and left bundle-branch block
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
J33.0 Polyp of nasal cavity
0.987 0.013 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.983 0.017 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.982 0.018 0.000
I44.2 Atrioventricular block, complete
0.972 0.028 0.000
L03 Cellulitis
0.963 0.037 0.000
N17-N19 Renal failure
0.962 0.038 0.000
E20-E35 Disorders of other endocrine glands
0.960 0.040 0.000
N18 Chronic renal failure
0.958 0.042 0.000
I44.7 Left bundle-branch block, unspecified
0.956 0.044 0.000
Chapter XIV Diseases of the genitourinary system
0.953 0.047 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.949 0.051 0.000
N17 Acute renal failure
0.943 0.057 0.000
I50.9 Heart failure, unspecified
0.937 0.063 0.000
J09-J18 Influenza and pneumonia
0.937 0.063 0.000
I99 Other and unspecified disorders of circulatory system
0.937 0.063 0.000
I49 Other cardiac arrhythmias
0.934 0.066 0.000
J33.8 Other polyp of sinus
0.931 0.069 0.000
E65-E68 Obesity and other hyperalimentation
0.929 0.071 0.000
N17.9 Acute renal failure, unspecified
0.928 0.072 0.000
L03.1 Cellulitis of other parts of limb
0.927 0.073 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.923 0.077 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.922 0.078 0.000
S90-S99 Injuries to the ankle and foot
0.921 0.079 0.000
J36 Peritonsillar abscess
0.920 0.080 0.000
J31.0 Chronic rhinitis
0.915 0.085 0.000
N18.5 Chronic kidney disease, stage 5
0.913 0.087 0.000
I34 Nonrheumatic mitral valve disorders
0.912 0.088 0.000
J40-J47 Chronic lower respiratory diseases
0.911 0.089 0.000
N18.4 Chronic kidney disease, stage 4
0.904 0.096 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.902 0.098 0.000
N18.9 Chronic renal failure, unspecified
0.901 0.099 0.000
I60-I69 Cerebrovascular diseases
0.901 0.099 0.000
L03.2 Cellulitis of face
0.894 0.106 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.893 0.107 0.000
L50-L54 Urticaria and erythema
0.890 0.110 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.888 0.112 0.000
E66 Obesity
0.879 0.121 0.000
T51 Toxic effect of alcohol
0.878 0.122 0.000
J43 Emphysema
0.877 0.123 0.000
J20-J22 Other acute lower respiratory infections
0.872 0.128 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.869 0.131 0.000
I42 Cardiomyopathy
0.868 0.132 0.000
E66.8 Other obesity
0.867 0.133 0.000
I34.0 Mitral (valve) insufficiency
0.863 0.137 0.000
E34 Other endocrine disorders
0.863 0.137 0.000
I51 Complications and ill-defined descriptions of heart disease
0.863 0.137 0.000
I30 Acute pericarditis
0.862 0.138 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.862 0.138 0.000
K82.8 Other specified diseases of gallbladder
0.861 0.139 0.000
K82 Other diseases of gallbladder
0.859 0.141 0.000
J33.9 Nasal polyp, unspecified
0.859 0.141 0.000
S92 Fracture of foot, except ankle
0.857 0.143 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.856 0.144 0.000
J35 Chronic diseases of tonsils and adenoids
0.854 0.146 0.000
I82 Other venous embolism and thrombosis
0.854 0.146 0.000
T79-T79 Certain early complications of trauma
0.853 0.147 0.000
J43.9 Emphysema, unspecified
0.853 0.147 0.000
N19 Unspecified renal failure
0.847 0.153 0.000
I49.0 Ventricular fibrillation and flutter
0.847 0.153 0.000
K86 Other diseases of pancreas
0.847 0.153 0.000
T51.0 Ethanol
0.847 0.153 0.000
E22 Hyperfunction of pituitary gland
0.845 0.155 0.000
I51.8 Other ill-defined heart diseases
0.842 0.158 0.000
L53 Other erythematous conditions
0.842 0.158 0.000
L03.8 Cellulitis of other sites
0.842 0.158 0.000
N25-N29 Other disorders of kidney and ureter
0.839 0.161 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.837 0.163 0.000
I95 Hypotension
0.836 0.164 0.000
I82.8 Embolism and thrombosis of other specified veins
0.836 0.164 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.834 0.166 0.000
E23 Hypofunction and other disorders of pituitary gland
0.834 0.166 0.000
I47 Paroxysmal tachycardia
0.828 0.172 0.000
J18 Pneumonia, organism unspecified
0.827 0.173 0.000
Chapter XI Diseases of the digestive system
0.825 0.175 0.000
S60-S69 Injuries to the wrist and hand
0.821 0.179 0.000
I49.3 Ventricular premature depolarisation
0.818 0.182 0.000
N10-N16 Renal tubulo-interstitial diseases
0.817 0.183 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.817 0.183 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
I77 Other disorders of arteries and arterioles
0.815 0.185 0.000
E28 Ovarian dysfunction
0.811 0.189 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.809 0.191 0.000
J35.1 Hypertrophy of tonsils
0.808 0.192 0.000
L53.9 Erythematous condition, unspecified
0.808 0.192 0.000
J18.1 Lobar pneumonia, unspecified
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.804 0.196 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.804 0.196 0.000
S32 Fracture of lumbar spine and pelvis
0.803 0.197 0.000
S10-S19 Injuries to the neck
0.802 0.198 0.000
K35-K38 Diseases of appendix
0.798 0.202 0.000
E00-E07 Disorders of thyroid gland
0.796 0.204 0.000
J44 Other chronic obstructive pulmonary disease
0.794 0.206 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.793 0.207 0.000
S92.3 Fracture of metatarsal bone
0.790 0.210 0.000
I61 Intracerebral haemorrhage
0.789 0.211 0.000
K35 Acute appendicitis
0.779 0.221 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.778 0.222 0.000
L08 Other local infections of skin and subcutaneous tissue
0.778 0.222 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.774 0.226 0.000
I60 Subarachnoid haemorrhage
0.772 0.228 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.772 0.228 0.000
N00-N08 Glomerular diseases
0.771 0.229 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.770 0.230 0.000
K86.1 Other chronic pancreatitis
0.770 0.230 0.000
J37 Chronic laryngitis and laryngotracheitis
0.768 0.231 0.000
N13 Obstructive and reflux uropathy
0.769 0.231 0.000
E03 Other hypothyroidism
0.766 0.234 0.000
S31 Open wound of abdomen, lower back and pelvis
0.765 0.234 0.000
I63 Cerebral infarction
0.764 0.236 0.000
S62 Fracture at wrist and hand level
0.764 0.236 0.000
I80 Phlebitis and thrombophlebitis
0.764 0.236 0.000
I95.1 Orthostatic hypotension
0.763 0.237 0.000
E70-E90 Metabolic disorders
0.763 0.237 0.000
L03.0 Cellulitis of finger and toe
0.760 0.240 0.000
L05 Pilonidal cyst
0.760 0.240 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.758 0.242 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.758 0.242 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.752 0.248 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.748 0.252 0.000
S36 Injury of intra-abdominal organs
0.747 0.253 0.000
Chapter VIII Diseases of the ear and mastoid process
0.747 0.253 0.000
L10-L14 Bullous disorders
0.745 0.255 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.745 0.255 0.000
E87.6 Hypokalaemia
0.744 0.256 0.000
S92.30 Fracture of metatarsal bone (closed)
0.742 0.258 0.000
I77.1 Stricture of artery
0.739 0.261 0.000
N18.2 Chronic kidney disease, stage 2
0.739 0.261 0.000
I49.8 Other specified cardiac arrhythmias
0.737 0.263 0.000
E29 Testicular dysfunction
0.737 0.263 0.000
I73 Other peripheral vascular diseases
0.736 0.264 0.000
E34.9 Endocrine disorder, unspecified
0.735 0.265 0.000
N18.0 End-stage renal disease
0.735 0.265 0.000
L40-L45 Papulosquamous disorders
0.734 0.266 0.000
E87.7 Fluid overload
0.733 0.267 0.000
E34.0 Carcinoid syndrome
0.732 0.268 0.000
K86.8 Other specified diseases of pancreas
0.732 0.268 0.000
J17 Pneumonia in diseases classified elsewhere
0.732 0.268 0.000
I42.6 Alcoholic cardiomyopathy
0.731 0.269 0.000
E22.1 Hyperprolactinaemia
0.731 0.269 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.725 0.275 0.000
I70 Atherosclerosis
0.725 0.275 0.000
S60 Superficial injury of wrist and hand
0.724 0.276 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.724 0.276 0.000
J11 Influenza, virus not identified
0.723 0.277 0.000
T86 Failure and rejection of transplanted organs and tissues
0.723 0.277 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.721 0.279 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.718 0.282 0.000
I42.0 Dilated cardiomyopathy
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
I47.1 Supraventricular tachycardia
0.715 0.285 0.000
J33.1 Polypoid sinus degeneration
0.715 0.285 0.000
I49.1 Atrial premature depolarisation
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S90 Superficial injury of ankle and foot
0.712 0.288 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.712 0.288 0.000
J30 Vasomotor and allergic rhinitis
0.712 0.288 0.000
K85 Acute pancreatitis
0.711 0.289 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.710 0.289 0.000
I30.1 Infective pericarditis
0.709 0.291 0.000
T56 Toxic effect of metals
0.709 0.291 0.000
I69 Sequelae of cerebrovascular disease
0.709 0.291 0.000
I44.5 Left posterior fascicular block
0.708 0.291 0.000
I44.4 Left anterior fascicular block
0.708 0.291 0.000
J00-J06 Acute upper respiratory infections
0.708 0.292 0.000
Q78 Other osteochondrodysplasias
0.708 0.292 0.000
Q50-Q56 Congenital malformations of genital organs
0.708 0.292 0.000
I63.9 Cerebral infarction, unspecified
0.707 0.293 0.000
E65 Localised adiposity
0.707 0.293 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.706 0.294 0.000
T20 Burn and corrosion of head and neck
0.706 0.294 0.000
J21 Acute bronchiolitis
0.706 0.294 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.705 0.295 0.000
Chapter XX External causes of morbidity and mortality
0.705 0.295 0.000
I30.9 Acute pericarditis, unspecified
0.705 0.295 0.000
T23 Burn and corrosion of wrist and hand
0.705 0.295 0.000
N18.8 Other chronic renal failure
0.704 0.296 0.000
I88 Nonspecific lymphadenitis
0.704 0.296 0.000
L04 Acute lymphadenitis
0.704 0.296 0.000
L01 Impetigo
0.704 0.296 0.000
L00 Staphylococcal scalded skin syndrome
0.704 0.296 0.000
K82.1 Hydrops of gallbladder
0.704 0.296 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.704 0.296 0.000
I89.1 Lymphangitis
0.704 0.296 0.000
J15.1 Pneumonia due to Pseudomonas
0.702 0.298 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.702 0.298 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.701 0.299 0.000
J22 Unspecified acute lower respiratory infection
0.700 0.300 0.000
N17.0 Acute renal failure with tubular necrosis
0.699 0.301 0.000
I87 Other disorders of veins
0.699 0.301 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.699 0.301 0.000
T92 Sequelae of injuries of upper limb
0.699 0.301 0.000
E23.0 Hypopituitarism
0.698 0.302 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.697 0.303 0.000
I36 Nonrheumatic tricuspid valve disorders
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.692 0.307 0.000
E40-E46 Malnutrition
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
K82.2 Perforation of gallbladder
0.690 0.310 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.690 0.310 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.690 0.310 0.000
E27 Other disorders of adrenal gland
0.689 0.311 0.000
T59 Toxic effect of other gases, fumes and vapours
0.689 0.311 0.000
J60-J70 Lung diseases due to external agents
0.689 0.311 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.689 0.311 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.688 0.312 0.000
E32 Diseases of thymus
0.688 0.312 0.000
E31 Polyglandular dysfunction
0.688 0.312 0.000
E30 Disorders of puberty, not elsewhere classified
0.688 0.312 0.000
E25 Adrenogenital disorders
0.688 0.312 0.000
E20 Hypoparathyroidism
0.688 0.312 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.687 0.313 0.000
N18.1 Chronic kidney disease, stage 1
0.687 0.313 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.687 0.313 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.686 0.314 0.000
S92.2 Fracture of other tarsal bone(s)
0.686 0.314 0.000
K86.9 Disease of pancreas, unspecified
0.685 0.315 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.684 0.316 0.000
E28.2 Polycystic ovarian syndrome
0.683 0.317 0.000
J15.5 Pneumonia due to Escherichia coli
0.683 0.317 0.000
K37 Unspecified appendicitis
0.682 0.318 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.680 0.319 0.000
J31.1 Chronic nasopharyngitis
0.680 0.320 0.000
J40 Bronchitis, not specified as acute or chronic
0.680 0.320 0.000
J20 Acute bronchitis
0.677 0.323 0.000
J15.4 Pneumonia due to other streptococci
0.677 0.323 0.000
E23.2 Diabetes insipidus
0.676 0.324 0.000
N17.8 Other acute renal failure
0.676 0.324 0.000
N17.2 Acute renal failure with medullary necrosis
0.676 0.324 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.676 0.324 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.676 0.324 0.000
S80-S89 Injuries to the knee and lower leg
0.676 0.324 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.675 0.325 0.000
N26 Unspecified contracted kidney
0.674 0.326 0.000
I49.9 Cardiac arrhythmia, unspecified
0.674 0.326 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.673 0.327 0.000
I42.8 Other cardiomyopathies
0.673 0.327 0.000
K82.4 Cholesterolosis of gallbladder
0.672 0.328 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.672 0.328 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.672 0.328 0.000
J12 Viral pneumonia, not elsewhere classified
0.672 0.328 0.000
J09 Influenza due to certain identified influenza virus
0.672 0.328 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.672 0.328 0.000
E03.8 Other specified hypothyroidism
0.671 0.329 0.000
E03.9 Hypothyroidism, unspecified
0.670 0.330 0.000
I49.2 Junctional premature depolarisation
0.669 0.331 0.000
J39 Other diseases of upper respiratory tract
0.668 0.332 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.667 0.333 0.000
E24 Cushing's syndrome
0.666 0.334 0.000
E67 Other hyperalimentation
0.666 0.334 0.000
E68 Sequelae of hyperalimentation
0.666 0.334 0.000
E26 Hyperaldosteronism
0.666 0.334 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.665 0.335 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.664 0.336 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.664 0.336 0.000
T79.7 Traumatic subcutaneous emphysema
0.663 0.337 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.662 0.338 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.662 0.338 0.000
T65 Toxic effect of other and unspecified substances
0.662 0.338 0.000
T62 Toxic effect of other noxious substances eaten as food
0.662 0.338 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.662 0.338 0.000
T60 Toxic effect of pesticides
0.662 0.338 0.000
T57 Toxic effect of other inorganic substances
0.662 0.338 0.000
T54 Toxic effect of corrosive substances
0.662 0.338 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.662 0.338 0.000
T52 Toxic effect of organic solvents
0.662 0.338 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.662 0.338 0.000
T55 Toxic effect of soaps and detergents
0.662 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.661 0.339 0.000
S37 Injury of urinary and pelvic organs
0.661 0.339 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.661 0.339 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.661 0.339 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.661 0.339 0.000
S98 Traumatic amputation of ankle and foot
0.660 0.339 0.000
S97 Crushing injury of ankle and foot
0.660 0.339 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.660 0.339 0.000
S95 Injury of blood vessels at ankle and foot level
0.660 0.339 0.000
S94 Injury of nerves at ankle and foot level
0.660 0.339 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.659 0.341 0.000
S32.3 Fracture of ilium
0.659 0.341 0.000
T21 Burn and corrosion of trunk
0.658 0.341 0.000
J31.2 Chronic pharyngitis
0.658 0.342 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.657 0.343 0.000
I31 Other diseases of pericardium
0.656 0.344 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.656 0.344 0.000
S91 Open wound of ankle and foot
0.656 0.344 0.000
L20-L30 Dermatitis and eczema
0.655 0.345 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.654 0.346 0.000
J41 Simple and mucopurulent chronic bronchitis
0.653 0.347 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.652 0.348 0.000
H65-H75 Diseases of middle ear and mastoid
0.650 0.350 0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.648 0.352 0.000
N13.4 Hydroureter
0.648 0.352 0.000
J00 Acute nasopharyngitis [common cold]
0.647 0.352 0.000
S10 Superficial injury of neck
0.647 0.353 0.000
S62.7 Multiple fractures of fingers
0.647 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.646 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.353 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.646 0.354 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.646 0.354 0.000
T58 Toxic effect of carbon monoxide
0.644 0.356 0.000
I61.8 Other intracerebral haemorrhage
0.643 0.357 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
S20-S29 Injuries to the thorax
0.642 0.358 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.641 0.359 0.000
I46 Cardiac arrest
0.641 0.359 0.000
T25 Burn and corrosion of ankle and foot
0.640 0.360 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.639 0.361 0.000
S31.1 Open wound of abdominal wall
0.639 0.361 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.639 0.361 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.639 0.361 0.000
L54 Erythema in diseases classified elsewhere
0.638 0.362 0.000
L51 Erythema multiforme
0.638 0.362 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.638 0.362 0.000
N13.3 Other and unspecified hydronephrosis
0.637 0.363 0.000
S92.4 Fracture of great toe
0.636 0.364 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.634 0.366 0.000
S62.2 Fracture of first metacarpal bone
0.633 0.366 0.000
J42 Unspecified chronic bronchitis
0.632 0.368 0.000
N25 Disorders resulting from impaired renal tubular function
0.632 0.368 0.000
S32.4 Fracture of acetabulum
0.632 0.368 0.000
D68 Other coagulation defects
0.631 0.369 0.000
N05 Unspecified nephritic syndrome
0.631 0.369 0.000
T86.1 Kidney transplant failure and rejection
0.631 0.369 0.000
Q78.0 Osteogenesis imperfecta
0.630 0.370 0.000
E66.1 Drug-induced obesity
0.630 0.370 0.000
E66.0 Obesity due to excess calories
0.630 0.370 0.000
Q12 Congenital lens malformations
0.630 0.370 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.630 0.370 0.000
I73.0 Raynaud's syndrome
0.630 0.370 0.000
K86.2 Cyst of pancreas
0.630 0.370 0.000
I44.6 Other and unspecified fascicular block
0.629 0.370 0.000
T51.8 Other alcohols
0.629 0.371 0.000
T51.3 Fusel oil
0.629 0.371 0.000
T51.2 2-Propanol
0.629 0.371 0.000
T51.1 Methanol
0.629 0.371 0.000
J43.8 Other emphysema
0.629 0.371 0.000
J43.2 Centrilobular emphysema
0.629 0.371 0.000
J43.1 Panlobular emphysema
0.629 0.371 0.000
J43.0 MacLeod's syndrome
0.629 0.371 0.000
S92.1 Fracture of talus
0.628 0.372 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.628 0.372 0.000
I95.8 Other hypotension
0.627 0.372 0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.627 0.373 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.627 0.373 0.000
I60.8 Other subarachnoid haemorrhage
0.627 0.373 0.000
L52 Erythema nodosum
0.626 0.374 0.000
I95.2 Hypotension due to drugs
0.626 0.374 0.000
J15.9 Bacterial pneumonia, unspecified
0.623 0.377 0.000
J15.8 Other bacterial pneumonia
0.623 0.377 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.623 0.377 0.000
J15.3 Pneumonia due to streptococcus, group B
0.623 0.377 0.000
S62.4 Multiple fractures of metacarpal bones
0.622 0.378 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.622 0.378 0.000
I42.5 Other restrictive cardiomyopathy
0.622 0.378 0.000
I42.4 Endocardial fibroelastosis
0.622 0.378 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.622 0.378 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.622 0.378 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.622 0.378 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.622 0.378 0.000
Q80-Q89 Other congenital malformations
0.621 0.379 0.000
N04 Nephrotic syndrome
0.621 0.379 0.000
S80 Superficial injury of lower leg
0.621 0.379 0.000
E28.3 Primary ovarian failure
0.620 0.380 0.000
T92.1 Sequelae of fracture of arm
0.620 0.380 0.000
T51.9 Alcohol, unspecified
0.620 0.380 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.619 0.381 0.000
Q76 Congenital malformations of spine and bony thorax
0.619 0.381 0.000
E85 Amyloidosis
0.619 0.381 0.000
E34.8 Other specified endocrine disorders
0.619 0.381 0.000
E34.5 Androgen resistance syndrome
0.619 0.381 0.000
E34.4 Constitutional tall stature
0.619 0.381 0.000
E34.3 Short stature, not elsewhere classified
0.619 0.381 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.619 0.381 0.000
E34.1 Other hypersecretion of intestinal hormones
0.619 0.381 0.000
I77.0 Arteriovenous fistula, acquired
0.619 0.381 0.000
I51.5 Myocardial degeneration
0.619 0.381 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.619 0.381 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.619 0.381 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.619 0.381 0.000
J10 Influenza due to identified influenza virus
0.619 0.381 0.000
I30.8 Other forms of acute pericarditis
0.618 0.382 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.618 0.382 0.000
I87.1 Compression of vein
0.618 0.382 0.000
S99 Other and unspecified injuries of ankle and foot
0.618 0.382 0.000
I45 Other conduction disorders
0.618 0.382 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.618 0.382 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.617 0.382 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.617 0.383 0.000
K82.3 Fistula of gallbladder
0.616 0.384 0.000
K82.0 Obstruction of gallbladder
0.616 0.384 0.000
S92.9 Fracture of foot, unspecified
0.615 0.385 0.000
S92.7 Multiple fractures of foot
0.615 0.385 0.000
S92.5 Fracture of other toe
0.615 0.385 0.000
Y52 Agents primarily affecting the cardiovascular system
0.614 0.386 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.614 0.386 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.614 0.386 0.000
L81 Other disorders of pigmentation
0.613 0.387 0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.613 0.387 0.000
J35.2 Hypertrophy of adenoids
0.613 0.387 0.000
I82.3 Embolism and thrombosis of renal vein
0.613 0.387 0.000
I82.1 Thrombophlebitis migrans
0.613 0.387 0.000
I82.0 Budd-Chiari syndrome
0.613 0.387 0.000
D68.2 Hereditary deficiency of other clotting factors
0.612 0.388 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.612 0.388 0.000
Q65 Congenital deformities of hip
0.612 0.388 0.000
T82.1 Mechanical complication of cardiac electronic device
0.611 0.389 0.000
N15 Other renal tubulo-interstitial diseases
0.609 0.390 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.608 0.391 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.608 0.392 0.000
I47.2 Ventricular tachycardia
0.608 0.392 0.000
L83 Acanthosis nigricans
0.607 0.393 0.000
T93 Sequelae of injuries of lower limb
0.607 0.393 0.000
Q51 Congenital malformations of uterus and cervix
0.606 0.394 0.000
T91 Sequelae of injuries of neck and trunk
0.606 0.394 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.606 0.394 0.000
E22.8 Other hyperfunction of pituitary gland
0.606 0.394 0.000
I71 Aortic aneurysm and dissection
0.606 0.394 0.000
E22.0 Acromegaly and pituitary gigantism
0.604 0.396 0.000
I10-I15 Hypertensive diseases
0.604 0.396 0.000
L53.8 Other specified erythematous conditions
0.604 0.396 0.000
L53.3 Other chronic figurate erythema
0.604 0.396 0.000
L53.2 Erythema marginatum
0.604 0.396 0.000
L53.1 Erythema annulare centrifugum
0.604 0.396 0.000
L53.0 Toxic erythema
0.604 0.396 0.000
L60-L75 Disorders of skin appendages
0.603 0.397 0.000
J37.0 Chronic laryngitis
0.603 0.397 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.603 0.397 0.000
I44.0 Atrioventricular block, first degree
0.603 0.397 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.602 0.398 0.000
K35.3 Acute appendicitis with localized peritonitis
0.601 0.398 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.601 0.398 0.000
N27 Small kidney of unknown cause
0.601 0.398 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.601 0.399 0.000
N99-N99 Other disorders of the genitourinary system
0.601 0.399 0.000
L27 Dermatitis due to substances taken internally
0.601 0.399 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.600 0.400 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.600 0.400 0.000
I97.0 Postcardiotomy syndrome
0.600 0.400 0.000
E10-E14 Diabetes mellitus
0.600 0.400 0.000
I95.0 Idiopathic hypotension
0.599 0.401 0.000
T82.3 Mechanical complication of other vascular grafts
0.599 0.401 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.598 0.402 0.000
E23.7 Disorder of pituitary gland, unspecified
0.598 0.402 0.000
E23.6 Other disorders of pituitary gland
0.598 0.402 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.598 0.402 0.000
E23.1 Drug-induced hypopituitarism
0.598 0.402 0.000
S36.0 Injury of spleen
0.596 0.404 0.000
I51.6 Cardiovascular disease, unspecified
0.596 0.404 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.596 0.404 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.596 0.404 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.595 0.404 0.000
S50-S59 Injuries to the elbow and forearm
0.595 0.405 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.595 0.405 0.000
E50-E64 Other nutritional deficiencies
0.595 0.405 0.000
J15.2 Pneumonia due to staphylococcus
0.594 0.406 0.000
T87 Complications peculiar to reattachment and amputation
0.594 0.406 0.000
J30.1 Allergic rhinitis due to pollen
0.593 0.407 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.593 0.407 0.000
J18.8 Other pneumonia, organism unspecified
0.593 0.407 0.000
J18.2 Hypostatic pneumonia, unspecified
0.593 0.407 0.000
S60.8 Other superficial injuries of wrist and hand
0.589 0.411 0.000
T14 Injury of unspecified body region
0.589 0.411 0.000
K81 Cholecystitis
0.588 0.412 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.588 0.412 0.000
S92.0 Fracture of calcaneus
0.588 0.412 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.587 0.413 0.000
J21.9 Acute bronchiolitis, unspecified
0.587 0.413 0.000
J81 Pulmonary oedema
0.587 0.413 0.000
J14 Pneumonia due to Haemophilus influenzae
0.586 0.414 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.586 0.414 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.586 0.414 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.586 0.414 0.000
Q75 Other congenital malformations of skull and face bones
0.586 0.414 0.000
Q74 Other congenital malformations of limb(s)
0.586 0.414 0.000
Q73 Reduction defects of unspecified limb
0.586 0.414 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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