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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74651669
log Bayes Factor = 14.1557
Chromosome 15   position 87,206,617  (GRCh37) Explore rs74651669 on Ensembl!
Variant rs74651669 is part of Cluster X0065

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
S00-S09 Injuries to the head
0.993 0.007 0.000
Chapter VIII Diseases of the ear and mastoid process
0.992 0.008 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.991 0.009 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.991 0.009 0.000
J09-J18 Influenza and pneumonia
0.985 0.015 0.000
C18 Malignant neoplasm of colon
0.983 0.017 0.000
C18.2 Ascending colon
0.979 0.021 0.000
J18 Pneumonia, organism unspecified
0.976 0.024 0.000
C15-C26 Malignant neoplasms of digestive organs
0.975 0.025 0.000
Chapter II Neoplasms
0.974 0.026 0.000
H53-H54 Visual disturbances and blindness
0.971 0.029 0.000
S02 Fracture of skull and facial bones
0.970 0.030 0.000
H30-H36 Disorders of choroid and retina
0.968 0.032 0.000
J40-J47 Chronic lower respiratory diseases
0.964 0.036 0.000
O60-O75 Complications of labour and delivery
0.961 0.039 0.000
T39.1 4-Aminophenol derivatives
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.959 0.041 0.000
J18.1 Lobar pneumonia, unspecified
0.958 0.042 0.000
S01 Open wound of head
0.956 0.044 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.955 0.045 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.951 0.049 0.000
J95-J99 Other diseases of the respiratory system
0.951 0.049 0.000
H02 Other disorders of eyelid
0.949 0.051 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.947 0.053 0.000
H65-H75 Diseases of middle ear and mastoid
0.943 0.057 0.000
H02.4 Ptosis of eyelid
0.940 0.060 0.000
S60-S69 Injuries to the wrist and hand
0.939 0.061 0.000
J00-J06 Acute upper respiratory infections
0.934 0.066 0.000
S01.8 Open wound of other parts of head
0.932 0.068 0.000
S40-S49 Injuries to the shoulder and upper arm
0.932 0.068 0.000
H01 Other inflammation of eyelid
0.926 0.074 0.000
H53 Visual disturbances
0.922 0.078 0.000
J98 Other respiratory disorders
0.919 0.081 0.000
H90-H95 Other disorders of ear
0.918 0.082 0.000
H33 Retinal detachments and breaks
0.915 0.085 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.913 0.087 0.000
C18.0 Caecum
0.906 0.094 0.000
T43.2 Other and unspecified antidepressants
0.903 0.097 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.897 0.103 0.000
H04 Disorders of lachrymal system
0.894 0.106 0.000
H35 Other retinal disorders
0.894 0.106 0.000
J47 Bronchiectasis
0.893 0.107 0.000
S02.2 Fracture of nasal bones
0.890 0.110 0.000
H10-H13 Disorders of conjunctiva
0.890 0.110 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.889 0.111 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.885 0.115 0.000
J43 Emphysema
0.883 0.117 0.000
H01.0 Blepharitis
0.880 0.120 0.000
C18.9 Colon, unspecified
0.876 0.124 0.000
J04 Acute laryngitis and tracheitis
0.871 0.129 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.869 0.131 0.000
O63 Long labour
0.866 0.134 0.000
H60-H62 Diseases of external ear
0.863 0.137 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.861 0.139 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.859 0.141 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.859 0.141 0.000
T66-T78 Other and unspecified effects of external causes
0.858 0.142 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.858 0.142 0.000
T79-T79 Certain early complications of trauma
0.857 0.143 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.855 0.145 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.855 0.145 0.000
J45 Asthma
0.854 0.146 0.000
H54 Blindness and low vision
0.854 0.146 0.000
H72 Perforation of tympanic membrane
0.851 0.149 0.000
H65 Nonsuppurative otitis media
0.844 0.156 0.000
S42 Fracture of shoulder and upper arm
0.842 0.158 0.000
E20-E35 Disorders of other endocrine glands
0.841 0.159 0.000
Chapter XIV Diseases of the genitourinary system
0.838 0.162 0.000
H55-H59 Other disorders of eye and adnexa
0.838 0.162 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.837 0.163 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.837 0.163 0.000
S02.20 Fracture of nasal bones (closed)
0.833 0.167 0.000
H33.2 Serous retinal detachment
0.833 0.167 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.829 0.171 0.000
S90-S99 Injuries to the ankle and foot
0.828 0.172 0.000
J04.0 Acute laryngitis
0.826 0.174 0.000
J43.9 Emphysema, unspecified
0.826 0.174 0.000
Q60-Q64 Congenital malformations of the urinary system
0.825 0.174 0.000
H53.2 Diplopia
0.825 0.175 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.824 0.176 0.000
J18.0 Bronchopneumonia, unspecified
0.824 0.176 0.000
M65-M68 Disorders of synovium and tendon
0.823 0.177 0.000
H11 Other disorders of conjunctiva
0.822 0.178 0.000
C18.4 Transverse colon
0.819 0.181 0.000
S70-S79 Injuries to the hip and thigh
0.818 0.182 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.818 0.182 0.000
S01.3 Open wound of ear
0.817 0.183 0.000
C18.6 Descending colon
0.817 0.183 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.815 0.185 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.813 0.187 0.000
J98.4 Other disorders of lung
0.810 0.190 0.000
H90 Conductive and sensorineural hearing loss
0.808 0.192 0.000
H66 Suppurative and unspecified otitis media
0.807 0.193 0.000
J45.9 Asthma, unspecified
0.805 0.195 0.000
N60-N64 Disorders of breast
0.804 0.196 0.000
T39.0 Salicylates
0.804 0.196 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.803 0.197 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.803 0.197 0.000
O43 Placental disorders
0.803 0.197 0.000
S02.4 Fracture of malar and maxillary bones
0.801 0.199 0.000
H91 Other hearing loss
0.800 0.200 0.000
J18.9 Pneumonia, unspecified
0.800 0.200 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.794 0.206 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.792 0.208 0.000
M20-M25 Other joint disorders
0.792 0.208 0.000
N64 Other disorders of breast
0.791 0.209 0.000
O63.1 Prolonged second stage (of labour)
0.791 0.209 0.000
H35.9 Retinal disorder, unspecified
0.791 0.209 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.789 0.211 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.788 0.212 0.000
J00 Acute nasopharyngitis [common cold]
0.787 0.213 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.787 0.213 0.000
M67 Other disorders of synovium and tendon
0.785 0.215 0.000
D50-D53 Nutritional anaemias
0.785 0.215 0.000
H65.3 Chronic mucoid otitis media
0.783 0.217 0.000
E27 Other disorders of adrenal gland
0.783 0.217 0.000
N64.5 Other signs and symptoms in breast
0.782 0.218 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.781 0.219 0.000
S02.7 Multiple fractures involving skull and facial bones
0.780 0.220 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.779 0.221 0.000
H53.4 Visual field defects
0.779 0.221 0.000
H46 Optic neuritis
0.779 0.221 0.000
M24 Other specific joint derangements
0.779 0.221 0.000
S20-S29 Injuries to the thorax
0.778 0.222 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.778 0.222 0.000
S40 Superficial injury of shoulder and upper arm
0.777 0.223 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.777 0.223 0.000
H33.5 Other retinal detachments
0.777 0.223 0.000
O41 Other disorders of amniotic fluid and membranes
0.776 0.223 0.000
O40 Polyhydramnios
0.776 0.224 0.000
D50 Iron deficiency anaemia
0.775 0.225 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.774 0.226 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.773 0.226 0.000
S01.9 Open wound of head, part unspecified
0.773 0.227 0.000
C18.7 Sigmoid colon
0.773 0.227 0.000
E10-E14 Diabetes mellitus
0.772 0.228 0.000
T42.4 Benzodiazepines
0.771 0.229 0.000
O62 Abnormalities of forces of labour
0.770 0.230 0.000
S10-S19 Injuries to the neck
0.770 0.230 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.770 0.230 0.000
H35.3 Degeneration of macula and posterior pole
0.769 0.231 0.000
H61 Other disorders of external ear
0.769 0.231 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.769 0.231 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.767 0.233 0.000
J98.8 Other specified respiratory disorders
0.767 0.233 0.000
Q80-Q89 Other congenital malformations
0.766 0.234 0.000
S02.0 Fracture of vault of skull
0.766 0.234 0.000
H40-H42 Glaucoma
0.766 0.234 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.766 0.234 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.764 0.236 0.000
H35.4 Peripheral retinal degeneration
0.762 0.238 0.000
J98.9 Respiratory disorder, unspecified
0.762 0.238 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.762 0.238 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.761 0.239 0.000
H33.3 Retinal breaks without detachment
0.760 0.240 0.000
T78 Adverse effects, not elsewhere classified
0.757 0.243 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.756 0.243 0.000
O66 Other obstructed labour
0.756 0.244 0.000
S02.8 Fractures of other skull and facial bones
0.756 0.244 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.756 0.244 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.755 0.245 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.755 0.245 0.000
O85-O92 Complications predominantly related to the puerperium
0.754 0.246 0.000
O47 False labour
0.754 0.246 0.000
O42 Premature rupture of membranes
0.754 0.246 0.000
T51 Toxic effect of alcohol
0.751 0.249 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.750 0.250 0.000
C18.5 Splenic flexure
0.750 0.250 0.000
D50.9 Iron deficiency anaemia, unspecified
0.750 0.250 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.749 0.251 0.000
C25 Malignant neoplasm of pancreas
0.748 0.252 0.000
Q61 Cystic kidney disease
0.747 0.253 0.000
S42.2 Fracture of upper end of humerus
0.747 0.253 0.000
H53.9 Visual disturbance, unspecified
0.745 0.254 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.745 0.255 0.000
H05 Disorders of orbit
0.743 0.257 0.000
C71 Malignant neoplasm of brain
0.740 0.260 0.000
M67.8 Other specified disorders of synovium and tendon
0.740 0.260 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.739 0.261 0.000
S69 Other and unspecified injuries of wrist and hand
0.739 0.261 0.000
S06 Intracranial injury
0.739 0.261 0.000
O00-O08 Pregnancy with abortive outcome
0.739 0.261 0.000
H53.1 Subjective visual disturbances
0.738 0.262 0.000
N20-N23 Urolithiasis
0.736 0.264 0.000
O36 Maternal care for other known or suspected foetal problems
0.735 0.265 0.000
H80-H83 Diseases of inner ear
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.734 0.266 0.000
H36 Retinal disorders in diseases classified elsewhere
0.732 0.268 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.730 0.270 0.000
C18.3 Hepatic flexure
0.730 0.270 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.729 0.271 0.000
S65 Injury of blood vessels at wrist and hand level
0.728 0.272 0.000
Q50-Q56 Congenital malformations of genital organs
0.727 0.273 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.726 0.274 0.000
C17 Malignant neoplasm of small intestine
0.725 0.274 0.000
S02.1 Fracture of base of skull
0.725 0.275 0.000
S02.3 Fracture of orbital floor
0.722 0.277 0.000
S60 Superficial injury of wrist and hand
0.722 0.278 0.000
S05 Injury of eye and orbit
0.721 0.279 0.000
D50.8 Other iron deficiency anaemias
0.721 0.279 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.721 0.279 0.000
H66.9 Otitis media, unspecified
0.720 0.280 0.000
N17-N19 Renal failure
0.719 0.281 0.000
H53.8 Other visual disturbances
0.718 0.282 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.718 0.282 0.000
O71 Other obstetric trauma
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
E24 Cushing's syndrome
0.715 0.285 0.000
N00-N08 Glomerular diseases
0.715 0.285 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.715 0.285 0.000
H91.9 Hearing loss, unspecified
0.715 0.285 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.714 0.286 0.000
S50-S59 Injuries to the elbow and forearm
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.712 0.288 0.000
S07 Crushing injury of head
0.712 0.288 0.000
S04 Injury of cranial nerves
0.712 0.288 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.712 0.288 0.000
S02.6 Fracture of mandible
0.712 0.288 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.711 0.289 0.000
H54.4 Blindness, one eye
0.711 0.289 0.000
J98.6 Disorders of diaphragm
0.711 0.289 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.711 0.289 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.711 0.289 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.710 0.290 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.710 0.290 0.000
T39.4 Antirheumatics, not elsewhere classified
0.710 0.290 0.000
T39.2 Pyrazolone derivatives
0.710 0.290 0.000
M05-M14 Inflammatory polyarthropathies
0.710 0.290 0.000
H02.5 Other disorders affecting eyelid function
0.709 0.291 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.707 0.293 0.000
J17 Pneumonia in diseases classified elsewhere
0.706 0.294 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.706 0.294 0.000
J12 Viral pneumonia, not elsewhere classified
0.706 0.294 0.000
J11 Influenza, virus not identified
0.706 0.294 0.000
J10 Influenza due to identified influenza virus
0.706 0.294 0.000
J09 Influenza due to certain identified influenza virus
0.706 0.294 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.705 0.295 0.000
C18.8 Overlapping lesion of colon
0.705 0.295 0.000
C18.1 Appendix
0.705 0.295 0.000
H74 Other disorders of middle ear and mastoid
0.705 0.295 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.704 0.296 0.000
J98.1 Pulmonary collapse
0.704 0.296 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.703 0.297 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.703 0.297 0.000
M23 Internal derangement of knee
0.702 0.298 0.000
C34 Malignant neoplasm of bronchus and lung
0.702 0.298 0.000
J14 Pneumonia due to Haemophilus influenzae
0.701 0.299 0.000
J18.8 Other pneumonia, organism unspecified
0.700 0.300 0.000
J18.2 Hypostatic pneumonia, unspecified
0.700 0.300 0.000
H90.5 Sensorineural hearing loss, unspecified
0.700 0.300 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.699 0.301 0.000
C23 Malignant neoplasm of gallbladder
0.699 0.301 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.697 0.303 0.000
M60-M63 Disorders of muscles
0.697 0.303 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.696 0.304 0.000
H02.6 Xanthelasma of eyelid
0.695 0.305 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.695 0.305 0.000
H11.0 Pterygium
0.695 0.305 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.694 0.305 0.000
H33.1 Retinoschisis and retinal cysts
0.694 0.306 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.694 0.306 0.000
H31 Other disorders of choroid
0.694 0.306 0.000
H30 Chorioretinal inflammation
0.694 0.306 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.693 0.307 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.693 0.307 0.000
T17 Foreign body in respiratory tract
0.692 0.308 0.000
J41 Simple and mucopurulent chronic bronchitis
0.691 0.309 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.691 0.309 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.691 0.309 0.000
M24.1 Other articular cartilage disorders
0.691 0.309 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.690 0.310 0.000
S67 Crushing injury of wrist and hand
0.690 0.310 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.690 0.310 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
O74 Complications of anaesthesia during labour and delivery
0.689 0.311 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.689 0.311 0.000
O60 Preterm delivery
0.689 0.311 0.000
S80-S89 Injuries to the knee and lower leg
0.688 0.312 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.688 0.312 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.688 0.312 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.312 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.312 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.312 0.000
H54.7 Unspecified visual loss
0.685 0.315 0.000
Q00-Q07 Congenital malformations of the nervous system
0.684 0.315 0.000
T43.9 Psychotropic drug, unspecified
0.684 0.316 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
T43.6 Psychostimulants with abuse potential
0.684 0.316 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.684 0.316 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.684 0.316 0.000
N18 Chronic renal failure
0.683 0.317 0.000
J46 Status asthmaticus
0.683 0.317 0.000
O43.1 Malformation of placenta
0.683 0.317 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.682 0.318 0.000
O45 Premature separation of placenta [abruptio placentae]
0.682 0.318 0.000
O44 Placenta praevia
0.682 0.318 0.000
O33 Maternal care for known or suspected disproportion
0.682 0.318 0.000
O31 Complications specific to multiple gestation
0.682 0.318 0.000
J96 Respiratory failure, not elsewhere classified
0.681 0.318 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.680 0.320 0.000
H02.2 Lagophthalmos
0.680 0.320 0.000
C21 Malignant neoplasm of anus and anal canal
0.680 0.320 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.680 0.320 0.000
S01.7 Multiple open wounds of head
0.679 0.321 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.679 0.321 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.679 0.321 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.679 0.321 0.000
T42.3 Barbiturates
0.679 0.321 0.000
T42.2 Succinimides and oxazolidinediones
0.679 0.321 0.000
T42.1 Iminostilbenes
0.679 0.321 0.000
T42.0 Hydantoin derivatives
0.679 0.321 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.679 0.321 0.000
S42.20 Fracture of upper end of humerus (closed)
0.678 0.322 0.000
O48 Prolonged pregnancy
0.678 0.322 0.000
M80-M85 Disorders of bone density and structure
0.678 0.322 0.000
S70 Superficial injury of hip and thigh
0.676 0.324 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.676 0.324 0.000
H70 Mastoiditis and related conditions
0.676 0.324 0.000
H68 Eustachian salpingitis and obstruction
0.676 0.324 0.000
H67 Otitis media in diseases classified elsewhere
0.676 0.324 0.000
C64-C68 Malignant neoplasms of urinary tract
0.676 0.324 0.000
J30-J39 Other diseases of upper respiratory tract
0.675 0.325 0.000
M23.8 Other internal derangements of knee
0.674 0.325 0.000
H73 Other disorders of tympanic membrane
0.674 0.326 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.673 0.327 0.000
E28 Ovarian dysfunction
0.672 0.328 0.000
S30.1 Contusion of abdominal wall
0.672 0.328 0.000
H54.0 Blindness, both eyes
0.672 0.328 0.000
E34 Other endocrine disorders
0.671 0.329 0.000
M06 Other rheumatoid arthritis
0.671 0.329 0.000
O73 Retained placenta and membranes, without haemorrhage
0.670 0.330 0.000
S68 Traumatic amputation of wrist and hand
0.670 0.330 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.669 0.331 0.000
S02.5 Fracture of tooth
0.669 0.331 0.000
J40 Bronchitis, not specified as acute or chronic
0.669 0.331 0.000
N62 Hypertrophy of breast
0.669 0.331 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.669 0.331 0.000
S48 Traumatic amputation of shoulder and upper arm
0.668 0.332 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.668 0.332 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.668 0.332 0.000
S44 Injury of nerves at shoulder and upper arm level
0.668 0.332 0.000
S41 Open wound of shoulder and upper arm
0.668 0.332 0.000
S47 Crushing injury of shoulder and upper arm
0.668 0.332 0.000
J01 Acute sinusitis
0.667 0.333 0.000
C51-C58 Malignant neoplasms of female genital organs
0.667 0.333 0.000
H35.7 Separation of retinal layers
0.666 0.334 0.000
N20 Calculus of kidney and ureter
0.666 0.334 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.666 0.334 0.000
C32 Malignant neoplasm of larynx
0.666 0.334 0.000
E65-E68 Obesity and other hyperalimentation
0.665 0.335 0.000
H01.9 Inflammation of eyelid, unspecified
0.664 0.336 0.000
H01.8 Other specified inflammation of eyelid
0.664 0.336 0.000
H01.1 Non-infectious dermatoses of eyelid
0.664 0.336 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.664 0.336 0.000
H69 Other disorders of Eustachian tube
0.664 0.336 0.000
E22 Hyperfunction of pituitary gland
0.663 0.336 0.000
H92 Otalgia and effusion of ear
0.663 0.337 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.663 0.337 0.000
T23 Burn and corrosion of wrist and hand
0.662 0.337 0.000
H53.6 Night blindness
0.661 0.339 0.000
H53.5 Colour vision deficiencies
0.661 0.339 0.000
H53.3 Other disorders of binocular vision
0.661 0.339 0.000
O61 Failed induction of labour
0.661 0.339 0.000
H61.8 Other specified disorders of external ear
0.661 0.339 0.000
H61.2 Impacted cerumen
0.661 0.339 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.660 0.339 0.000
M91-M94 Chondropathies
0.660 0.340 0.000
S01.5 Open wound of lip and oral cavity
0.660 0.340 0.000
S64 Injury of nerves at wrist and hand level
0.660 0.340 0.000
J81 Pulmonary oedema
0.659 0.341 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.659 0.341 0.000
J98.3 Compensatory emphysema
0.659 0.341 0.000
J98.2 Interstitial emphysema
0.659 0.341 0.000
E14 Unspecified diabetes mellitus
0.659 0.341 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.658 0.342 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.658 0.342 0.000
M67.1 Other contracture of tendon (sheath)
0.658 0.342 0.000
N05 Unspecified nephritic syndrome
0.657 0.343 0.000
E27.1 Primary adrenocortical insufficiency
0.657 0.343 0.000
S42.3 Fracture of shaft of humerus
0.657 0.343 0.000
H33.4 Traction detachment of retina
0.656 0.344 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.655 0.345 0.000
O30 Multiple gestation
0.655 0.345 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.654 0.345 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.653 0.347 0.000
O63.9 Long labour, unspecified
0.653 0.347 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.652 0.347 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.652 0.347 0.000
Q61.3 Polycystic kidney, unspecified
0.652 0.348 0.000
J42 Unspecified chronic bronchitis
0.652 0.348 0.000
C71.1 Frontal lobe
0.652 0.348 0.000
H18 Other disorders of cornea
0.651 0.349 0.000
O69.8 Labour and delivery complicated by other cord complications
0.651 0.349 0.000
O03 Spontaneous abortion
0.651 0.349 0.000
E26 Hyperaldosteronism
0.650 0.350 0.000
H20 Iridocyclitis
0.649 0.351 0.000
J15.1 Pneumonia due to Pseudomonas
0.649 0.351 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.649 0.351 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.648 0.352 0.000
T81 Complications of procedures, not elsewhere classified
0.647 0.353 0.000
S20 Superficial injury of thorax
0.646 0.354 0.000
J20-J22 Other acute lower respiratory infections
0.646 0.354 0.000
H02.0 Entropion and trichiasis of eyelid
0.646 0.354 0.000
T51.9 Alcohol, unspecified
0.645 0.355 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.645 0.355 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.644 0.356 0.000
S02.70 Multiple fractures involving skull and facial bones (closed)
0.643 0.357 0.000
J06.9 Acute upper respiratory infection, unspecified
0.642 0.358 0.000
S42.1 Fracture of scapula
0.642 0.358 0.000
H04.1 Other disorders of lachrymal gland
0.642 0.358 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.642 0.358 0.000
C26.0 Intestinal tract, part unspecified
0.641 0.359 0.000
H04.9 Disorder of lachrymal system, unspecified
0.641 0.359 0.000
H04.8 Other disorders of lachrymal system
0.641 0.359 0.000
H04.6 Other changes in lachrymal passages
0.641 0.359 0.000
H04.4 Chronic inflammation of lachrymal passages
0.641 0.359 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.641 0.359 0.000
H04.0 Dacryoadenitis
0.641 0.359 0.000
H35.5 Hereditary retinal dystrophy
0.641 0.359 0.000
H35.2 Other proliferative retinopathy
0.641 0.359 0.000
H35.1 Retinopathy of prematurity
0.641 0.359 0.000
M24.0 Loose body in joint
0.641 0.359 0.000
N18.9 Chronic renal failure, unspecified
0.641 0.359 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.639 0.360 0.000
M06.9 Rheumatoid arthritis, unspecified
0.639 0.361 0.000
H93 Other disorders of ear, not elsewhere classified
0.639 0.361 0.000
S02.21 Fracture of nasal bones (open)
0.638 0.362 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.638 0.362 0.000
H47.3 Other disorders of optic disk
0.638 0.362 0.000
E10 Insulin-dependent diabetes mellitus
0.637 0.363 0.000
S42.0 Fracture of clavicle
0.637 0.363 0.000
Q27 Other congenital malformations of peripheral vascular system
0.636 0.364 0.000
H90.0 Conductive hearing loss, bilateral
0.635 0.364 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.635 0.365 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.635 0.365 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.635 0.365 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.635 0.365 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.635 0.365 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.635 0.365 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.634 0.366 0.000
T40.6 Other and unspecified narcotics
0.634 0.366 0.000
J43.8 Other emphysema
0.633 0.367 0.000
J43.2 Centrilobular emphysema
0.633 0.367 0.000
J43.1 Panlobular emphysema
0.633 0.367 0.000
J43.0 MacLeod's syndrome
0.633 0.367 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.633 0.367 0.000
T40.2 Other opioids
0.633 0.367 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.633 0.367 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.633 0.367 0.000
H72.0 Central perforation of tympanic membrane
0.632 0.368 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.632 0.368 0.000
S62 Fracture at wrist and hand level
0.632 0.368 0.000
O72 Postpartum haemorrhage
0.632 0.368 0.000
N20.1 Calculus of ureter
0.630 0.370 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.630 0.370 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.630 0.370 0.000
H61.3 Acquired stenosis of external ear canal
0.630 0.370 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.629 0.371 0.000
S00 Superficial injury of head
0.629 0.371 0.000
S10 Superficial injury of neck
0.628 0.372 0.000
M24.5 Contracture of joint
0.628 0.372 0.000
M24.2 Disorder of ligament
0.628 0.372 0.000
M65 Synovitis and tenosynovitis
0.627 0.373 0.000
H02.3 Blepharochalasis
0.627 0.373 0.000
H16 Keratitis
0.627 0.373 0.000
H11.8 Other specified disorders of conjunctiva
0.626 0.374 0.000
H02.8 Other specified disorders of eyelid
0.626 0.374 0.000
E24.9 Cushing's syndrome, unspecified
0.625 0.375 0.000
J04.2 Acute laryngotracheitis
0.624 0.375 0.000
J04.1 Acute tracheitis
0.624 0.375 0.000
S01.2 Open wound of nose
0.624 0.376 0.000
T17.2 Foreign body in pharynx
0.623 0.377 0.000
H60 Otitis externa
0.623 0.377 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.623 0.377 0.000
H04.2 Epiphora
0.623 0.377 0.000
Q61.2 Polycystic kidney, adult type
0.622 0.378 0.000
T79.8 Other early complications of trauma
0.621 0.378 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.621 0.379 0.000
N75 Diseases of Bartholin's gland
0.621 0.379 0.000
Chapter XX External causes of morbidity and mortality
0.621 0.379 0.000
C45 Mesothelioma
0.620 0.380 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.620 0.380 0.000
S02.00 Fracture of vault of skull (closed)
0.620 0.380 0.000
E27.9 Disorder of adrenal gland, unspecified
0.619 0.381 0.000
H65.4 Other chronic nonsuppurative otitis media
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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