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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74745420
log Bayes Factor = 15.0287
Chromosome 3   position 125,702,812  (GRCh37) Explore rs74745420 on Ensembl!
Variant rs74745420 is part of Cluster X0026

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
N18 Chronic renal failure
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
I63 Cerebral infarction
0.997 0.003 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.997 0.003 0.000
I63.9 Cerebral infarction, unspecified
0.995 0.005 0.000
R79 Other abnormal findings of blood chemistry
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.991 0.009 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.986 0.014 0.000
R94 Abnormal results of function studies
0.983 0.017 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.980 0.020 0.000
R94.5 Abnormal results of liver function studies
0.979 0.021 0.000
W00-W19 Falls
0.976 0.024 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.976 0.024 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.972 0.028 0.000
N10-N16 Renal tubulo-interstitial diseases
0.968 0.032 0.000
B35-B49 Mycoses
0.966 0.034 0.000
N18.9 Chronic renal failure, unspecified
0.959 0.041 0.000
I51 Complications and ill-defined descriptions of heart disease
0.958 0.042 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.954 0.046 0.000
W19 Unspecified fall
0.953 0.047 0.000
S50-S59 Injuries to the elbow and forearm
0.953 0.047 0.000
N30-N39 Other diseases of urinary system
0.951 0.049 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.950 0.050 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.948 0.052 0.000
N18.5 Chronic kidney disease, stage 5
0.944 0.056 0.000
W19.9 Unspecified place
0.943 0.057 0.000
E20-E35 Disorders of other endocrine glands
0.941 0.059 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.939 0.061 0.000
Chapter XXI Factors influencing health status and contact with health services
0.939 0.061 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.937 0.063 0.000
N18.0 End-stage renal disease
0.931 0.069 0.000
I44 Atrioventricular and left bundle-branch block
0.930 0.070 0.000
B37 Candidiasis
0.929 0.071 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.926 0.074 0.000
E70-E90 Metabolic disorders
0.925 0.075 0.000
S52 Fracture of forearm
0.917 0.083 0.000
N17 Acute renal failure
0.915 0.085 0.000
I51.8 Other ill-defined heart diseases
0.908 0.092 0.000
N25-N29 Other disorders of kidney and ureter
0.906 0.094 0.000
B37.0 Candidal stomatitis
0.904 0.096 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.900 0.100 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.895 0.105 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.894 0.106 0.000
E78.5 Hyperlipidaemia, unspecified
0.892 0.108 0.000
R22.0 Localised swelling, mass and lump, head
0.888 0.112 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.887 0.113 0.000
I95 Hypotension
0.886 0.114 0.000
N00-N08 Glomerular diseases
0.885 0.115 0.000
T93 Sequelae of injuries of lower limb
0.883 0.117 0.000
N13 Obstructive and reflux uropathy
0.882 0.118 0.000
R21 Rash and other nonspecific skin eruption
0.880 0.120 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.872 0.128 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.872 0.128 0.000
I74 Arterial embolism and thrombosis
0.869 0.131 0.000
I49 Other cardiac arrhythmias
0.863 0.137 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.863 0.137 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.858 0.142 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.858 0.142 0.000
I44.7 Left bundle-branch block, unspecified
0.857 0.143 0.000
I45 Other conduction disorders
0.856 0.144 0.000
N17.9 Acute renal failure, unspecified
0.855 0.145 0.000
I60 Subarachnoid haemorrhage
0.854 0.146 0.000
N18.3 Chronic kidney disease, stage 3
0.854 0.146 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.854 0.146 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.851 0.149 0.000
I44.2 Atrioventricular block, complete
0.850 0.150 0.000
Z85 Personal history of malignant neoplasm
0.849 0.151 0.000
S80-S89 Injuries to the knee and lower leg
0.849 0.151 0.000
Z98 Other postsurgical states
0.848 0.152 0.000
I51.9 Heart disease, unspecified
0.848 0.152 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.847 0.153 0.000
A00-A09 Intestinal infectious diseases
0.845 0.155 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.844 0.156 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.841 0.159 0.000
R22.1 Localised swelling, mass and lump, neck
0.840 0.160 0.000
S52.1 Fracture of upper end of radius
0.840 0.160 0.000
Z94 Transplanted organ and tissue status
0.837 0.163 0.000
I95.9 Hypotension, unspecified
0.837 0.163 0.000
I05-I09 Chronic rheumatic heart diseases
0.836 0.164 0.000
S90-S99 Injuries to the ankle and foot
0.835 0.165 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.833 0.167 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.829 0.171 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.822 0.178 0.000
I69 Sequelae of cerebrovascular disease
0.819 0.181 0.000
N18.4 Chronic kidney disease, stage 4
0.818 0.182 0.000
E27 Other disorders of adrenal gland
0.817 0.183 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.813 0.187 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.811 0.189 0.000
S40-S49 Injuries to the shoulder and upper arm
0.808 0.192 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.807 0.193 0.000
Z90.7 Acquired absence of genital organ(s)
0.806 0.194 0.000
E50-E64 Other nutritional deficiencies
0.805 0.195 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.802 0.198 0.000
N32 Other disorders of bladder
0.800 0.200 0.000
Y86 Sequelae of other accidents
0.800 0.200 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.799 0.201 0.000
Z98.0 Intestinal bypass and anastomosis status
0.798 0.202 0.000
N18.8 Other chronic renal failure
0.798 0.202 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.798 0.202 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.797 0.203 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.797 0.203 0.000
E21.3 Hyperparathyroidism, unspecified
0.793 0.206 0.000
R77 Other abnormalities of plasma proteins
0.793 0.207 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.792 0.208 0.000
Z99.2 Dependence on renal dialysis
0.791 0.209 0.000
B65-B83 Helminthiases
0.790 0.210 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.790 0.210 0.000
I61 Intracerebral haemorrhage
0.789 0.211 0.000
Z86 Personal history of certain other diseases
0.789 0.211 0.000
T86 Failure and rejection of transplanted organs and tissues
0.788 0.212 0.000
S52.10 Fracture of upper end of radius (closed)
0.784 0.216 0.000
W18 Other fall on same level
0.783 0.217 0.000
I73 Other peripheral vascular diseases
0.782 0.218 0.000
A30-A49 Other bacterial diseases
0.780 0.220 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.780 0.220 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.779 0.220 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.779 0.221 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.779 0.221 0.000
I33 Acute and subacute endocarditis
0.778 0.222 0.000
N05 Unspecified nephritic syndrome
0.775 0.225 0.000
W10 Fall on and from stairs and steps
0.775 0.225 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.775 0.225 0.000
T39.1 4-Aminophenol derivatives
0.774 0.226 0.000
B99-B99 Other infectious diseases
0.771 0.229 0.000
B49 Unspecified mycosis
0.771 0.229 0.000
N36 Other disorders of urethra
0.770 0.230 0.000
S52.5 Fracture of lower end of radius
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
Z90.5 Acquired absence of kidney
0.765 0.235 0.000
I72 Other aneurysm
0.765 0.235 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.765 0.235 0.000
X60-X84 Intentional self-harm
0.764 0.236 0.000
R76 Other abnormal immunological findings in serum
0.764 0.236 0.000
B07 Viral warts
0.763 0.237 0.000
Z22 Carrier of infectious disease
0.762 0.238 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.762 0.238 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.761 0.239 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.761 0.239 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.759 0.241 0.000
S60-S69 Injuries to the wrist and hand
0.759 0.241 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.759 0.241 0.000
T93.2 Sequelae of other fractures of lower limb
0.758 0.242 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.758 0.242 0.000
T92 Sequelae of injuries of upper limb
0.757 0.243 0.000
B37.8 Candidiasis of other sites
0.756 0.244 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.754 0.246 0.000
I49.5 Sick sinus syndrome
0.752 0.248 0.000
B00 Herpesviral [herpes simplex] infections
0.751 0.249 0.000
R94.3 Abnormal results of cardiovascular function studies
0.748 0.252 0.000
I45.5 Other specified heart block
0.746 0.254 0.000
Z94.8 Other transplanted organ and tissue status
0.746 0.254 0.000
Z86.7 Personal history of diseases of the circulatory system
0.745 0.255 0.000
Chapter XXII Codes for special purposes
0.744 0.256 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
I62 Other nontraumatic intracranial haemorrhage
0.743 0.257 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.742 0.257 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.742 0.258 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.742 0.258 0.000
S81 Open wound of lower leg
0.741 0.259 0.000
N19 Unspecified renal failure
0.740 0.260 0.000
W08 Fall involving other furniture
0.738 0.262 0.000
W20-W49 Exposure to inanimate mechanical forces
0.738 0.262 0.000
I31 Other diseases of pericardium
0.737 0.263 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.735 0.265 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.733 0.267 0.000
E24 Cushing's syndrome
0.733 0.267 0.000
N35 Urethral stricture
0.733 0.267 0.000
I08 Multiple valve diseases
0.733 0.267 0.000
N18.2 Chronic kidney disease, stage 2
0.732 0.267 0.000
T90 Sequelae of injuries of head
0.732 0.268 0.000
B35 Dermatophytosis
0.732 0.268 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.731 0.269 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
W19.2 School, other institution and public administrative area
0.728 0.271 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.728 0.272 0.000
S52.8 Fracture of other parts of forearm
0.728 0.272 0.000
D80-D89 Certain disorders involving the immune mechanism
0.728 0.272 0.000
Z93 Artificial opening status
0.727 0.273 0.000
E28 Ovarian dysfunction
0.725 0.275 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.725 0.275 0.000
T93.1 Sequelae of fracture of femur
0.725 0.275 0.000
W07 Fall involving chair
0.725 0.275 0.000
E78.4 Other hyperlipidaemia
0.724 0.276 0.000
I77 Other disorders of arteries and arterioles
0.724 0.276 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.724 0.276 0.000
I49.9 Cardiac arrhythmia, unspecified
0.723 0.277 0.000
E40-E46 Malnutrition
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.719 0.281 0.000
B44 Aspergillosis
0.719 0.281 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.719 0.281 0.000
N71 Inflammatory disease of uterus, except cervix
0.718 0.282 0.000
N40-N51 Diseases of male genital organs
0.718 0.282 0.000
N03 Chronic nephritic syndrome
0.718 0.282 0.000
S52.7 Multiple fractures of forearm
0.717 0.283 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
N18.1 Chronic kidney disease, stage 1
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
Z99.1 Dependence on respirator
0.716 0.284 0.000
T82.1 Mechanical complication of cardiac electronic device
0.716 0.284 0.000
Z53.8 Procedure not carried out for other reasons
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
I63.8 Other cerebral infarction
0.715 0.285 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.715 0.285 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.715 0.285 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.715 0.285 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.715 0.285 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.715 0.285 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.715 0.285 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.715 0.285 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.715 0.285 0.000
R71 Abnormality of red blood cells
0.715 0.285 0.000
E22 Hyperfunction of pituitary gland
0.714 0.286 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
I73.0 Raynaud's syndrome
0.711 0.289 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.711 0.289 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.711 0.289 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.711 0.289 0.000
T82.3 Mechanical complication of other vascular grafts
0.711 0.289 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.711 0.289 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.709 0.291 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.709 0.291 0.000
S52.0 Fracture of upper end of ulna
0.708 0.292 0.000
Z22.3 Carrier of other specified bacterial diseases
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
N32.8 Other specified disorders of bladder
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.706 0.294 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.706 0.294 0.000
T79-T79 Certain early complications of trauma
0.706 0.294 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.705 0.295 0.000
R94.7 Abnormal results of other endocrine function studies
0.705 0.295 0.000
R94.6 Abnormal results of thyroid function studies
0.705 0.295 0.000
R94.4 Abnormal results of kidney function studies
0.705 0.295 0.000
R94.2 Abnormal results of pulmonary function studies
0.705 0.295 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.705 0.295 0.000
R94.0 Abnormal results of function studies of central nervous system
0.705 0.295 0.000
S50 Superficial injury of forearm
0.703 0.297 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.703 0.297 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.702 0.298 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.702 0.298 0.000
Z89 Acquired absence of limb
0.701 0.299 0.000
W17 Other fall from one level to another
0.700 0.300 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.700 0.300 0.000
W15 Fall from cliff
0.700 0.300 0.000
W14 Fall from tree
0.700 0.300 0.000
W12 Fall on and from scaffolding
0.700 0.300 0.000
W11 Fall on and from ladder
0.700 0.300 0.000
W09 Fall involving playground equipment
0.700 0.300 0.000
W05 Fall involving wheelchair
0.700 0.300 0.000
W04 Fall while being carried or supported by other persons
0.700 0.300 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.700 0.300 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.700 0.300 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.700 0.300 0.000
W00 Fall on same level involving ice and snow
0.700 0.300 0.000
I44.6 Other and unspecified fascicular block
0.700 0.300 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.699 0.301 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.699 0.301 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.699 0.301 0.000
Z98.8 Other specified postsurgical states
0.697 0.303 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.697 0.303 0.000
Z49 Care involving dialysis
0.696 0.304 0.000
E87.7 Fluid overload
0.696 0.304 0.000
A04 Other bacterial intestinal infections
0.696 0.304 0.000
Z46 Fitting and adjustment of other devices
0.696 0.304 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.694 0.306 0.000
N15 Other renal tubulo-interstitial diseases
0.694 0.306 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.694 0.306 0.000
N11 Chronic tubulo-interstitial nephritis
0.694 0.306 0.000
N10 Acute tubulo-interstitial nephritis
0.694 0.306 0.000
I30 Acute pericarditis
0.693 0.307 0.000
R47-R49 Symptoms and signs involving speech and voice
0.693 0.307 0.000
B48 Other mycoses, not elsewhere classified
0.692 0.308 0.000
B47 Mycetoma
0.692 0.308 0.000
B46 Zygomycosis
0.692 0.308 0.000
B45 Cryptococcosis
0.692 0.308 0.000
B43 Chromomycosis and phaeomycotic abscess
0.692 0.308 0.000
B42 Sporotrichosis
0.692 0.308 0.000
B41 Paracoccidioidomycosis
0.692 0.308 0.000
B40 Blastomycosis
0.692 0.308 0.000
B39 Histoplasmosis
0.692 0.308 0.000
B38 Coccidioidomycosis
0.692 0.308 0.000
B36 Other superficial mycoses
0.692 0.308 0.000
Z97 Presence of other devices
0.692 0.308 0.000
Z41 Procedures for purposes other than remedying health state
0.692 0.308 0.000
V20-V29 Motorcycle rider injured in transport accident
0.690 0.310 0.000
R23 Other skin changes
0.688 0.312 0.000
I47 Paroxysmal tachycardia
0.688 0.312 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.688 0.312 0.000
Y85 Sequelae of transport accidents
0.688 0.312 0.000
N99-N99 Other disorders of the genitourinary system
0.687 0.313 0.000
I49.4 Other and unspecified premature depolarisation
0.687 0.313 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.687 0.313 0.000
I51.6 Cardiovascular disease, unspecified
0.687 0.313 0.000
I51.5 Myocardial degeneration
0.687 0.313 0.000
I51.4 Myocarditis, unspecified
0.687 0.313 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.687 0.313 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.687 0.313 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.687 0.313 0.000
I51.0 Cardiac septal defect, acquired
0.687 0.313 0.000
N28.0 Ischaemia and infarction of kidney
0.685 0.315 0.000
I95.2 Hypotension due to drugs
0.684 0.316 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.684 0.316 0.000
I51.7 Cardiomegaly
0.684 0.316 0.000
R79.0 Abnormal level of blood mineral
0.684 0.316 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.684 0.316 0.000
W19.3 Sports and athletics area
0.684 0.316 0.000
W19.8 Other specified place
0.683 0.316 0.000
W19.5 Trade and service area
0.683 0.316 0.000
W19.0 Home
0.683 0.316 0.000
W19.7 Farm
0.683 0.316 0.000
W19.6 Industrial and construction area
0.683 0.316 0.000
W19.1 Residential institution
0.683 0.316 0.000
S59 Other and unspecified injuries of forearm
0.683 0.316 0.000
S58 Traumatic amputation of forearm
0.683 0.316 0.000
S57 Crushing injury of forearm
0.683 0.316 0.000
S56 Injury of muscle and tendon at forearm level
0.683 0.316 0.000
S55 Injury of blood vessels at forearm level
0.683 0.316 0.000
S54 Injury of nerves at forearm level
0.683 0.316 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.683 0.316 0.000
S51 Open wound of forearm
0.683 0.316 0.000
I45.2 Bifascicular block
0.683 0.317 0.000
R74 Abnormal serum enzyme levels
0.682 0.318 0.000
N26 Unspecified contracted kidney
0.682 0.318 0.000
N37 Urethral disorders in diseases classified elsewhere
0.682 0.318 0.000
N34 Urethritis and urethral syndrome
0.682 0.318 0.000
N33 Bladder disorders in diseases classified elsewhere
0.682 0.318 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.681 0.318 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.318 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.681 0.318 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.681 0.318 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.681 0.318 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.681 0.318 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.681 0.318 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.681 0.318 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.681 0.318 0.000
T36 Poisoning by systemic antibiotics
0.681 0.318 0.000
T98 Sequelae of other and unspecified effects of external causes
0.680 0.320 0.000
T95 Sequelae of burns, corrosions and frostbite
0.680 0.320 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.680 0.320 0.000
T91 Sequelae of injuries of neck and trunk
0.680 0.320 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
Chapter II Neoplasms
0.679 0.321 0.000
W06 Fall involving bed
0.679 0.321 0.000
Z43 Attention to artificial openings
0.678 0.322 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.677 0.323 0.000
I70 Atherosclerosis
0.676 0.323 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.675 0.325 0.000
W13 Fall from, out of or through building or structure
0.674 0.326 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.674 0.326 0.000
E34 Other endocrine disorders
0.674 0.326 0.000
E32 Diseases of thymus
0.674 0.326 0.000
E31 Polyglandular dysfunction
0.674 0.326 0.000
E30 Disorders of puberty, not elsewhere classified
0.674 0.326 0.000
E29 Testicular dysfunction
0.674 0.326 0.000
E26 Hyperaldosteronism
0.674 0.326 0.000
E25 Adrenogenital disorders
0.674 0.326 0.000
E20 Hypoparathyroidism
0.674 0.326 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.673 0.326 0.000
Z94.0 Kidney transplant status
0.673 0.326 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.673 0.327 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.672 0.328 0.000
I99 Other and unspecified disorders of circulatory system
0.672 0.328 0.000
R73 Elevated blood glucose level
0.672 0.328 0.000
T40.4 Other synthetic narcotics
0.671 0.329 0.000
E27.1 Primary adrenocortical insufficiency
0.671 0.329 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.670 0.329 0.000
I74.5 Embolism and thrombosis of iliac artery
0.668 0.332 0.000
N13.8 Other obstructive and reflux uropathy
0.668 0.332 0.000
Z93.2 Ileostomy status
0.668 0.332 0.000
N76 Other inflammation of vagina and vulva
0.668 0.332 0.000
N30 Cystitis
0.668 0.332 0.000
I44.3 Other and unspecified atrioventricular block
0.667 0.333 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.333 0.000
I44.5 Left posterior fascicular block
0.667 0.333 0.000
I44.4 Left anterior fascicular block
0.667 0.333 0.000
B37.7 Candidal septicaemia
0.666 0.334 0.000
B37.6 Candidal endocarditis
0.666 0.334 0.000
B37.5 Candidal meningitis
0.666 0.334 0.000
B37.4 Candidiasis of other urogenital sites
0.666 0.334 0.000
B37.2 Candidiasis of skin and nail
0.666 0.334 0.000
B37.1 Pulmonary candidiasis
0.666 0.334 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.666 0.334 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.665 0.335 0.000
N73 Other female pelvic inflammatory diseases
0.664 0.336 0.000
Z84 Family history of other conditions
0.664 0.336 0.000
E88 Other metabolic disorders
0.663 0.337 0.000
E85 Amyloidosis
0.663 0.337 0.000
E84 Cystic fibrosis
0.663 0.337 0.000
E79 Disorders of purine and pyrimidine metabolism
0.663 0.337 0.000
E77 Disorders of glycoprotein metabolism
0.663 0.337 0.000
E76 Disorders of glycosaminoglycan metabolism
0.663 0.337 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.663 0.337 0.000
E74 Other disorders of carbohydrate metabolism
0.663 0.337 0.000
E73 Lactose intolerance
0.663 0.337 0.000
E72 Other disorders of amino-acid metabolism
0.663 0.337 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.663 0.337 0.000
E70 Disorders of aromatic amino-acid metabolism
0.663 0.337 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.663 0.337 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.662 0.338 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.662 0.338 0.000
D86 Sarcoidosis
0.662 0.338 0.000
S52.50 Fracture of lower end of radius (closed)
0.662 0.338 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.661 0.339 0.000
T39.0 Salicylates
0.661 0.339 0.000
N39 Other disorders of urinary system
0.661 0.339 0.000
B15-B19 Viral hepatitis
0.659 0.341 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.658 0.342 0.000
S52.9 Fracture of forearm, part unspecified
0.658 0.342 0.000
S52.4 Fracture of shafts of both ulna and radius
0.658 0.342 0.000
S52.3 Fracture of shaft of radius
0.658 0.342 0.000
S52.2 Fracture of shaft of ulna
0.658 0.342 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.658 0.342 0.000
S99 Other and unspecified injuries of ankle and foot
0.657 0.342 0.000
E61 Deficiency of other nutrient elements
0.657 0.343 0.000
N17.8 Other acute renal failure
0.656 0.344 0.000
N17.2 Acute renal failure with medullary necrosis
0.656 0.344 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.656 0.344 0.000
N17.0 Acute renal failure with tubular necrosis
0.656 0.344 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.656 0.344 0.000
S92 Fracture of foot, except ankle
0.656 0.344 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.656 0.344 0.000
B91 Sequelae of poliomyelitis
0.655 0.345 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.655 0.345 0.000
I38 Endocarditis, valve unspecified
0.655 0.345 0.000
I61.8 Other intracerebral haemorrhage
0.655 0.345 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.653 0.347 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.653 0.347 0.000
R30-R39 Symptoms and signs involving the urinary system
0.653 0.347 0.000
I95.1 Orthostatic hypotension
0.652 0.348 0.000
Chapter X Diseases of the respiratory system
0.652 0.348 0.000
E23 Hypofunction and other disorders of pituitary gland
0.650 0.350 0.000
N05.9 Unspecified
0.650 0.350 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.650 0.350 0.000
N27 Small kidney of unknown cause
0.650 0.350 0.000
N25 Disorders resulting from impaired renal tubular function
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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