TreeWAS – Variant ID: rs74877722

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44 Other chronic obstructive pulmonary disease	0.000	0.000	1.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.000	1.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.000	1.000
J43.9 Emphysema, unspecified	0.000	0.002	0.998
J43 Emphysema	0.000	0.006	0.994
J40-J47 Chronic lower respiratory diseases	0.000	0.010	0.990
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.034	0.966
J43.2 Centrilobular emphysema	0.000	0.190	0.810
J43.8 Other emphysema	0.000	0.247	0.753
J41 Simple and mucopurulent chronic bronchitis	0.000	0.280	0.720
J43.1 Panlobular emphysema	0.000	0.287	0.713
J43.0 MacLeod's syndrome	0.000	0.287	0.713
J42 Unspecified chronic bronchitis	0.000	0.289	0.711
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.317	0.683
J41.0 Simple chronic bronchitis	0.000	0.474	0.526
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.484	0.516
J41.1 Mucopurulent chronic bronchitis	0.000	0.484	0.516
J46 Status asthmaticus	0.000	0.490	0.510
J47 Bronchiectasis	0.000	0.551	0.449
J40 Bronchitis, not specified as acute or chronic	0.000	0.623	0.377
J45 Asthma	0.000	0.664	0.336
J45.8 Mixed asthma	0.000	0.774	0.226
J45.9 Asthma, unspecified	0.000	0.780	0.220
J45.1 Nonallergic asthma	0.000	0.782	0.218
J45.0 Predominantly allergic asthma	0.000	0.932	0.067
N86 Erosion and ectropion of cervix uteri	0.043	0.957	0.000
R27.0 Ataxia, unspecified	0.000	0.971	0.029
R27 Other lack of coordination	0.000	0.973	0.027
R29.6 Tendency to fall, not elsewhere classified	0.000	0.974	0.026
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.974	0.026
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.976	0.024
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.976	0.024
R26 Abnormalities of gait and mobility	0.000	0.977	0.023
R27.8 Other and unspecified lack of coordination	0.000	0.978	0.022
I69.3 Sequelae of cerebral infarction	0.000	0.979	0.021
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.979	0.021
I69 Sequelae of cerebrovascular disease	0.000	0.980	0.020
R26.0 Ataxic gait	0.000	0.980	0.020
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.980	0.020
R29.4 Clicking hip	0.000	0.982	0.018
R29.3 Abnormal posture	0.000	0.982	0.018
R29.0 Tetany	0.000	0.982	0.018
R29.1 Meningismus	0.000	0.983	0.017
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.983	0.017
R26.1 Paralytic gait	0.000	0.983	0.017
R29.2 Abnormal reflex	0.000	0.983	0.017
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.984	0.016
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.984	0.016
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.985	0.015
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.015	0.985	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.986	0.014
N61 Inflammatory disorders of breast	0.000	0.987	0.013
M54.16 Radiculopathy (Lumbar region)	0.000	0.989	0.011
G81.9 Hemiplegia, unspecified	0.000	0.990	0.010
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.990	0.010
R26.3 Immobility	0.000	0.991	0.009
J38.4 Oedema of larynx	0.009	0.991	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.992	0.008
I35.1 Aortic (valve) insufficiency	0.000	0.992	0.008
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.008	0.992	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.993	0.007
G81 Hemiplegia	0.000	0.993	0.007
K86.9 Disease of pancreas, unspecified	0.000	0.993	0.007
N64.1 Fat necrosis of breast	0.000	0.994	0.006
N64 Other disorders of breast	0.000	0.994	0.006
N64.4 Mastodynia	0.000	0.994	0.006
Y42.5 Other oestrogens and progestogens	0.000	0.994	0.006
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.006	0.994	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
N64.9 Disorder of breast, unspecified	0.000	0.994	0.006
I35.9 Aortic valve disorder, unspecified	0.000	0.994	0.006
N64.5 Other signs and symptoms in breast	0.000	0.994	0.006
C34.1 Upper lobe, bronchus or lung	0.000	0.995	0.005
G81.1 Spastic hemiplegia	0.000	0.995	0.005
H33.3 Retinal breaks without detachment	0.000	0.995	0.005
K86.8 Other specified diseases of pancreas	0.000	0.995	0.005
G81.0 Flaccid hemiplegia	0.000	0.995	0.005
Z86.0 Personal history of other neoplasms	0.000	0.995	0.005
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.995	0.005
K86 Other diseases of pancreas	0.000	0.995	0.005
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.995	0.005
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.005	0.995	0.000
N64.3 Galactorrhoea not associated with childbirth	0.000	0.995	0.005
N64.2 Atrophy of breast	0.000	0.995	0.005
N64.0 Fissure and fistula of nipple	0.000	0.995	0.005
G82 Paraplegia and tetraplegia	0.000	0.996	0.004
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.996	0.004
E55 Vitamin D deficiency	0.000	0.996	0.004
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
G82.1 Spastic paraplegia	0.000	0.996	0.004
I35 Nonrheumatic aortic valve disorders	0.000	0.996	0.004
R25 Abnormal involuntary movements	0.000	0.996	0.004
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.004	0.996	0.000
G82.5 Tetraplegia, unspecified	0.000	0.996	0.004
G82.4 Spastic tetraplegia	0.000	0.996	0.004
J38.7 Other diseases of larynx	0.004	0.996	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.996	0.004
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.996	0.004
G82.2 Paraplegia, unspecified	0.000	0.996	0.004
C56 Malignant neoplasm of ovary	0.000	0.996	0.004
K86.2 Cyst of pancreas	0.000	0.996	0.004
J38.3 Other diseases of vocal cords	0.004	0.996	0.000
F17.1 Harmful use	0.000	0.996	0.004
G82.3 Flaccid tetraplegia	0.000	0.997	0.003
G82.0 Flaccid paraplegia	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
N81.5 Vaginal enterocele	0.000	0.997	0.003
E55.0 Rickets, active	0.000	0.997	0.003
R25.0 Abnormal head movements	0.000	0.997	0.003
S90.0 Contusion of ankle	0.003	0.997	0.000
O16 Unspecified maternal hypertension	0.000	0.997	0.003
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
K80.4 Calculus of bile duct with cholecystitis	0.000	0.997	0.003
N60-N64 Disorders of breast	0.000	0.997	0.003
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.003	0.997	0.000
C22.0 Liver cell carcinoma	0.000	0.997	0.003
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.997	0.003
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.997	0.003
O15 Eclampsia	0.000	0.997	0.003
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
J91 Pleural effusion in conditions classified elsewhere	0.003	0.997	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.997	0.002
J38.0 Paralysis of vocal cords and larynx	0.003	0.997	0.000
C22.9 Liver, unspecified	0.000	0.997	0.003
J38.6 Stenosis of larynx	0.002	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
G80 Infantile cerebral palsy	0.000	0.997	0.002
K29.0 Acute haemorrhagic gastritis	0.003	0.997	0.000
L93.0 Discoid lupus erythematosus	0.000	0.997	0.003
O81.3 Other and unspecified forceps delivery	0.002	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.997	0.002
K86.1 Other chronic pancreatitis	0.000	0.997	0.002
N64.8 Other specified disorders of breast	0.000	0.998	0.002
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.002	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.002	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.002	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.002	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.002	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.002	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.002	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
R25.3 Fasciculation	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
M15.8 Other polyarthrosis	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
M15.1 Heberden's nodes (with arthropathy)	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
O14.2 HELLP syndrome	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.000	0.998	0.002
O15.2 Eclampsia in the puerperium	0.000	0.998	0.002
O15.1 Eclampsia in labour	0.000	0.998	0.002
O15.0 Eclampsia in pregnancy	0.000	0.998	0.002
O43.1 Malformation of placenta	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
M15.3 Secondary multiple arthrosis	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.000	0.998	0.002
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
Z31.2 In vitro fertilisation	0.000	0.998	0.002
M15 Polyarthrosis	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.000	0.998	0.002
K65.8 Other peritonitis	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.000	0.998	0.002
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.002
G80.1 Spastic diplegia	0.000	0.998	0.002
J38.5 Laryngeal spasm	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
B02.3 Zoster ocular disease	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
E50-E64 Other nutritional deficiencies	0.000	0.998	0.002
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.998	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.998	0.002
G80.8 Other infantile cerebral palsy	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
C71.7 Brain stem	0.002	0.998	0.000
I35.8 Other aortic valve disorders	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M15.0 Primary generalised (osteo)arthrosis	0.002	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
G83 Other paralytic syndromes	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
D29.1 Prostate	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M15.4 Erosive (osteo)arthrosis	0.002	0.998	0.000
E51 Thiamine deficiency	0.000	0.998	0.002
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
F17.2 Dependence syndrome	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
T86.4 Liver transplant failure and rejection	0.000	0.998	0.002
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
E61.2 Magnesium deficiency	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.998	0.002
E63 Other nutritional deficiencies	0.000	0.998	0.002
E50 Vitamin A deficiency	0.000	0.998	0.002
E60 Dietary zinc deficiency	0.000	0.998	0.002
E59 Dietary selenium deficiency	0.000	0.998	0.002
E54 Ascorbic acid deficiency	0.000	0.998	0.002
E52 Niacin deficiency [pellagra]	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
F17.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F17.8 Other mental and behavioural disorders	0.000	0.998	0.002
F17.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F17.6 Amnesic syndrome	0.000	0.998	0.002
F17.5 Psychotic disorder	0.000	0.998	0.002
F17.4 Withdrawal state with delirium	0.000	0.998	0.002
F17.3 Withdrawal state	0.000	0.998	0.002
F17.0 Acute intoxication	0.000	0.998	0.002
C22.7 Other specified carcinomas of liver	0.000	0.998	0.002
C22.4 Other sarcomas of liver	0.000	0.998	0.002
C22.3 Angiosarcoma of liver	0.000	0.998	0.002
C22.2 Hepatoblastoma	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
T86 Failure and rejection of transplanted organs and tissues	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
M15.9 Polyarthrosis, unspecified	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
X78.0 Home	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
G83.5 Locked-in syndrome	0.000	0.998	0.001
G83.3 Monoplegia, unspecified	0.000	0.998	0.001
G83.0 Diplegia of upper limbs	0.000	0.998	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
W44.0 Home	0.000	0.998	0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
W50.9 Unspecified place	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.000	0.998	0.002
O12.1 Gestational proteinuria	0.000	0.998	0.001
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.001
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.001
E51.1 Beriberi	0.000	0.998	0.001
O12.2 Gestational oedema with proteinuria	0.000	0.998	0.001
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.000	0.998	0.001
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.001
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.001
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.001
E61.6 Vanadium deficiency	0.000	0.998	0.001
E61.5 Molybdenum deficiency	0.000	0.998	0.001
E61.4 Chromium deficiency	0.000	0.998	0.001
E61.3 Manganese deficiency	0.000	0.998	0.001
E61.0 Copper deficiency	0.000	0.998	0.001
K07.1 Anomalies of jaw-cranial base relationship	0.002	0.998	0.000
Z31.8 Other procreative management	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
G83.1 Monoplegia of lower limb	0.000	0.998	0.001
H18.4 Corneal degeneration	0.000	0.998	0.002
R23.4 Changes in skin texture	0.000	0.998	0.002
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
Z31 Procreative management	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.000	0.998	0.001
E53.0 Riboflavin deficiency	0.000	0.998	0.001
K51.8 Other ulcerative colitis	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.998	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.998	0.002
O43.8 Other placental disorders	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.001	0.998	0.000
D35.0 Adrenal gland	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.001
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.001
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.001
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.001
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.001
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.001
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.001
E53.8 Deficiency of other specified B group vitamins	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.001
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.001
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.001
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.001
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.001
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.001
E64.3 Sequelae of rickets	0.000	0.998	0.001
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.001
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.001
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.001
I05.8 Other mitral valve diseases	0.000	0.998	0.001
O32.4 Maternal care for high head at term	0.000	0.998	0.002
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.998	0.001
T86.3 Heart-lung transplant failure and rejection	0.000	0.998	0.001
T86.2 Heart transplant failure and rejection	0.000	0.998	0.001
B02 Zoster [herpes zoster]	0.000	0.998	0.002
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.001
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.001
O32.8 Maternal care for other malpresentation of foetus	0.000	0.998	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
M53.96 Dorsopathy, unspecified (Lumbar region)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
G83.2 Monoplegia of upper limb	0.000	0.999	0.001
I74.8 Embolism and thrombosis of other arteries	0.000	0.999	0.001
O81.0 Low forceps delivery	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
Y42.4 Oral contraceptives	0.000	0.999	0.001
M53 Other dorsopathies, not elsewhere classified	0.001	0.999	0.000
C18.3 Hepatic flexure	0.000	0.999	0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.999	0.001
M53.9 Dorsopathy, unspecified	0.001	0.999	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.999	0.001
O43 Placental disorders	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
E61.1 Iron deficiency	0.000	0.999	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.999	0.001
T01.2 Open wounds involving multiple regions of upper limb(s)	0.001	0.999	0.000
Y42.2 Antithyroid drugs	0.000	0.999	0.001
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.999	0.001
E56.9 Vitamin deficiency, unspecified	0.000	0.999	0.001
E56.8 Deficiency of other vitamins	0.000	0.999	0.001
E56.0 Deficiency of vitamin E	0.000	0.999	0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.999	0.001
Y95 Nosocomial condition	0.000	0.999	0.001
Y47.1 Benzodiazepines	0.000	0.999	0.001
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.999	0.001
Z31.6 General counselling and advice on procreation	0.000	0.999	0.001
Z31.5 Genetic counselling	0.000	0.999	0.001
Z31.3 Other assisted fertilisation methods	0.000	0.999	0.001
Z31.1 Artifical insemination	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
M15.99 Polyosteoarthritis, unspecified	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.999	0.001
C71.2 Temporal lobe	0.001	0.999	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.999	0.001
H53.8 Other visual disturbances	0.000	0.999	0.001
M53.2 Spinal instabilities	0.001	0.999	0.000
W50.2 School, other institution and public administrative area	0.001	0.999	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.999	0.001
B02.7 Disseminated zoster	0.000	0.999	0.001
B02.1 Zoster meningitis	0.000	0.999	0.001
B02.0 Zoster encephalitis	0.000	0.999	0.001
H20.0 Acute and subacute iridocyclitis	0.000	0.999	0.001
H54.4 Blindness, one eye	0.000	0.999	0.001
K25.4 Chronic or unspecified with haemorrhage	0.000	0.999	0.001
O12.0 Gestational oedema	0.000	0.999	0.001
O32.0 Maternal care for unstable lie	0.000	0.999	0.001
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.000	0.999	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.999	0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
M86.8 Other osteomyelitis	0.000	0.999	0.001
Y49.2 Other and unspecified antidepressants	0.000	0.999	0.001
Z31.9 Procreative management, unspecified	0.000	0.999	0.001
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M53.1 Cervicobrachial syndrome	0.001	0.999	0.000
M53.0 Cervicocranial syndrome	0.001	0.999	0.000
Y49.5 Other antipsychotics and neuroleptics	0.000	0.999	0.001
Y48 Anaesthetics and therapeutic gases	0.000	0.999	0.001
M53.22 Spinal instabilities (Cervical region)	0.001	0.999	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.001	0.999	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.001	0.999	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.001	0.999	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M86.86 Other osteomyelitis (Lower leg)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations