TreeWAS – Variant ID: rs7517337

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.176	0.824	0.000
T39.1 4-Aminophenol derivatives	0.174	0.826	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.171	0.829	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.156	0.844	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.156	0.844	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.154	0.846	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.149	0.851	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.148	0.852	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.146	0.854	0.000
T36 Poisoning by systemic antibiotics	0.145	0.855	0.000
T39.0 Salicylates	0.143	0.857	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.143	0.857	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.142	0.858	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.139	0.861	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.135	0.865	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.135	0.865	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.131	0.869	0.000
T39.4 Antirheumatics, not elsewhere classified	0.126	0.874	0.000
T39.2 Pyrazolone derivatives	0.126	0.874	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.126	0.874	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.126	0.874	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.126	0.874	0.000
T47.6 Antidiarrhoeal drugs	0.125	0.875	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.125	0.875	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.124	0.876	0.000
T47.0 Histamine H(2)-receptor antagonists	0.123	0.877	0.000
T47.4 Other laxatives	0.123	0.877	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.122	0.877	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.122	0.878	0.000
T42.4 Benzodiazepines	0.120	0.880	0.000
T36.0 Penicillins	0.119	0.881	0.000
T47.2 Stimulant laxatives	0.119	0.881	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.115	0.885	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.114	0.886	0.000
T36.4 Tetracyclines	0.113	0.887	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.112	0.888	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.112	0.888	0.000
T47.7 Emetics	0.112	0.888	0.000
T47.5 Digestants	0.112	0.888	0.000
T47.3 Saline and osmotic laxatives	0.112	0.888	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.112	0.888	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.112	0.888	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.112	0.888	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.112	0.888	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.112	0.888	0.000
T44.0 Anticholinesterase agents	0.112	0.888	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.111	0.889	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.111	0.889	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.111	0.889	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.110	0.890	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.110	0.890	0.000
T38.1 Thyroid hormones and substitutes	0.109	0.891	0.000
T50.4 Drugs affecting uric acid metabolism	0.108	0.892	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.107	0.893	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.107	0.893	0.000
T46.7 Peripheral vasodilators	0.107	0.893	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.107	0.893	0.000
I21.9 Acute myocardial infarction, unspecified	0.107	0.893	0.000
T50.7 Analeptics and opioid receptor antagonists	0.106	0.894	0.000
T50.5 Appetite depressants	0.106	0.894	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.106	0.894	0.000
T50.1 Loop [high-ceiling] diuretics	0.106	0.894	0.000
T50.0 Mineralocorticoids and their antagonists	0.106	0.894	0.000
T36.3 Macrolides	0.106	0.894	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.105	0.895	0.000
T38.9 Other and unspecified hormone antagonists	0.104	0.895	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.104	0.895	0.000
T38.7 Androgens and anabolic congeners	0.104	0.895	0.000
T38.5 Other oestrogens and progestogens	0.104	0.895	0.000
T38.4 Oral contraceptives	0.104	0.895	0.000
T38.2 Antithyroid drugs	0.104	0.895	0.000
T38.0 Glucocorticoids and synthetic analogues	0.104	0.895	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.104	0.896	0.000
T36.9 Systemic antibiotic, unspecified	0.104	0.896	0.000
T36.8 Other systemic antibiotics	0.104	0.896	0.000
T36.7 Antifungal antibiotics, systemically used	0.104	0.896	0.000
T36.6 Rifamycins	0.104	0.896	0.000
T36.5 Aminoglycosides	0.104	0.896	0.000
T36.2 Chloramphenicol group	0.104	0.896	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.104	0.896	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.103	0.897	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.103	0.897	0.000
T50.8 Diagnostic agents	0.103	0.897	0.000
T46.1 Calcium-channel blockers	0.101	0.899	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.097	0.903	0.000
T37.5 Antiviral drugs	0.097	0.903	0.000
T37.4 Anthelminthics	0.097	0.903	0.000
T37.3 Other antiprotozoal drugs	0.097	0.903	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.097	0.903	0.000
T37.1 Antimycobacterial drugs	0.097	0.903	0.000
T37.0 Sulphonamides	0.097	0.903	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.097	0.903	0.000
T42.3 Barbiturates	0.097	0.903	0.000
T42.2 Succinimides and oxazolidinediones	0.097	0.903	0.000
T42.0 Hydantoin derivatives	0.096	0.904	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.096	0.904	0.000
T49.9 Topical agent, unspecified	0.094	0.905	0.000
T49.8 Other topical agents	0.094	0.905	0.000
T49.7 Dental drugs, topically applied	0.094	0.905	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.094	0.905	0.000
T49.5 Ophthalmological drugs and preparations	0.094	0.905	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.094	0.905	0.000
T49.3 Emollients, demulcents and protectants	0.094	0.905	0.000
T49.2 Local astringents and local detergents	0.094	0.905	0.000
T49.1 Antipruritics	0.094	0.905	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.094	0.906	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.090	0.910	0.000
T48.5 Anti-common-cold drugs	0.090	0.910	0.000
T48.4 Expectorants	0.090	0.910	0.000
T48.3 Antitussives	0.090	0.910	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.090	0.910	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.090	0.910	0.000
T48.0 Oxytocic drugs	0.090	0.910	0.000
T41.5 Therapeutic gases	0.088	0.912	0.000
T41.4 Anaesthetic, unspecified	0.088	0.912	0.000
T41.3 Local anaesthetics	0.088	0.912	0.000
T41.2 Other and unspecified general anaesthetics	0.088	0.912	0.000
T41.1 Intravenous anaesthetics	0.088	0.912	0.000
T41.0 Inhaled anaesthetics	0.088	0.912	0.000
T42.1 Iminostilbenes	0.087	0.913	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.079	0.921	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.078	0.922	0.000
T45.0 Antiallergic and antiemetic drugs	0.074	0.926	0.000
T45.2 Vitamins, not elsewhere classified	0.072	0.928	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.071	0.929	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.069	0.931	0.000
T45.8 Other primarily systemic and haematological agents	0.069	0.931	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.069	0.931	0.000
T45.6 Fibrinolysis-affecting drugs	0.069	0.931	0.000
T45.4 Iron and its compounds	0.069	0.931	0.000
T45.3 Enzymes, not elsewhere classified	0.069	0.931	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.067	0.933	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.063	0.936	0.000
K35.8 Acute appendicitis, other and unspecified	0.057	0.943	0.000
K35 Acute appendicitis	0.057	0.943	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.053	0.946	0.000
K35.9 Acute appendicitis, unspecified	0.051	0.949	0.000
T40.1 Heroin	0.051	0.949	0.000
T40.5 Cocaine	0.049	0.950	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.048	0.952	0.000
T40.8 Lysergide [LSD]	0.048	0.952	0.000
T40.7 Cannabis (derivatives)	0.048	0.952	0.000
T40.3 Methadone	0.048	0.952	0.000
T40.0 Opium	0.048	0.952	0.000
T45.5 Anticoagulants	0.048	0.952	0.000
T40.4 Other synthetic narcotics	0.048	0.952	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.961	0.039
K35.2 Acute appendicitis with generalized peritonitis	0.035	0.965	0.000
T40.6 Other and unspecified narcotics	0.029	0.971	0.000
K35-K38 Diseases of appendix	0.027	0.973	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.976	0.024
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.022	0.977	0.001
K36 Other appendicitis	0.022	0.978	0.000
T40.2 Other opioids	0.022	0.978	0.000
K38 Other diseases of appendix	0.022	0.978	0.000
K35.3 Acute appendicitis with localized peritonitis	0.021	0.978	0.000
K38.8 Other specified diseases of appendix	0.021	0.979	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.018	0.982	0.000
T43.6 Psychostimulants with abuse potential	0.016	0.983	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.016	0.983	0.001
K38.0 Hyperplasia of appendix	0.016	0.984	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.016	0.984	0.000
K38.2 Diverticulum of appendix	0.016	0.984	0.000
K38.3 Fistula of appendix	0.016	0.984	0.000
T43.9 Psychotropic drug, unspecified	0.015	0.984	0.001
H33.0 Retinal detachment with retinal break	0.015	0.985	0.000
K38.9 Disease of appendix, unspecified	0.014	0.986	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.014	0.986	0.000
K37 Unspecified appendicitis	0.013	0.987	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.012	0.987	0.001
M19.01 Primary arthrosis of other joints (Shoulder region)	0.012	0.988	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.010	0.990	0.000
K38.1 Appendicular concretions	0.009	0.990	0.000
H50.9 Strabismus, unspecified	0.009	0.991	0.000
H50.0 Convergent concomitant strabismus	0.009	0.991	0.000
C18.6 Descending colon	0.000	0.991	0.009
H50 Other strabismus	0.009	0.991	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.991	0.009
H50.2 Vertical strabismus	0.008	0.992	0.000
I49.3 Ventricular premature depolarisation	0.008	0.992	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.008	0.992	0.000
N75.1 Abscess of Bartholin's gland	0.008	0.992	0.000
H50.1 Divergent concomitant strabismus	0.007	0.993	0.000
H50.8 Other specified strabismus	0.007	0.993	0.000
S52.6 Fracture of lower end of both ulna and radius	0.007	0.993	0.000
H50.3 Intermittent heterotropia	0.007	0.993	0.000
H50.4 Other and unspecified heterotropia	0.007	0.993	0.000
H50.6 Mechanical strabismus	0.006	0.993	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.006	0.994	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.001	0.994	0.005
N43.3 Hydrocele, unspecified	0.000	0.995	0.005
M79.69 Pain in limb (Site unspecified)	0.000	0.995	0.005
H00.1 Chalazion	0.000	0.995	0.005
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.995	0.005
N75 Diseases of Bartholin's gland	0.005	0.995	0.000
S05.8 Other injuries of eye and orbit	0.005	0.995	0.000
N75.0 Cyst of Bartholin's gland	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
H00 Hordeolum and chalazion	0.000	0.996	0.004
H44.2 Degenerative myopia	0.004	0.996	0.000
H50.5 Heterophoria	0.004	0.996	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.996	0.004
D34 Benign neoplasm of thyroid gland	0.000	0.996	0.004
S81.0 Open wound of knee	0.004	0.996	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.004	0.996	0.000
S52.10 Fracture of upper end of radius (closed)	0.004	0.996	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.996	0.004
N75.8 Other diseases of Bartholin's gland	0.004	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.996	0.004
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.004	0.996	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.996	0.004
S52.1 Fracture of upper end of radius	0.004	0.996	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
S52 Fracture of forearm	0.004	0.996	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.996	0.004
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.997	0.003
Z71.8 Other specified counselling	0.000	0.997	0.003
S52.9 Fracture of forearm, part unspecified	0.003	0.997	0.000
S52.2 Fracture of shaft of ulna	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
G95.8 Other specified diseases of spinal cord	0.003	0.997	0.000
Z52.0 Blood donor	0.000	0.997	0.003
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.997	0.003
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.997	0.003
O36.1 Maternal care for other isoimmunisation	0.000	0.997	0.003
S52.11 Fracture of upper end of radius (open)	0.003	0.997	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.003	0.997	0.000
S52.20 Fracture of shaft of ulna (closed)	0.003	0.997	0.000
S52.4 Fracture of shafts of both ulna and radius	0.003	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
S72.20 Subtrochanteric fracture (closed)	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
O36.2 Maternal care for hydrops foetalis	0.000	0.997	0.002
H44.1 Other endophthalmitis	0.003	0.997	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.997	0.003
S52.21 Fracture of shaft of ulna (open)	0.002	0.997	0.000
S52.0 Fracture of upper end of ulna	0.003	0.997	0.000
S52.01 Fracture of upper end of ulna (open)	0.003	0.997	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.002	0.997	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.000	0.997	0.002
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.997	0.000
S52.3 Fracture of shaft of radius	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
S05.6 Penetrating wound of eyeball without foreign body	0.002	0.998	0.000
H44 Disorders of globe	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.000	0.998	0.002
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
N43.4 Spermatocele	0.000	0.998	0.002
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
Z52.4 Kidney donor	0.000	0.998	0.002
C92 Myeloid leukaemia	0.000	0.998	0.002
C92.9 Myeloid leukaemia, unspecified	0.000	0.998	0.002
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.998	0.002
S05.7 Avulsion of eye	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
T51.0 Ethanol	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.002
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
C91.1 Chronic lymphocytic leukaemia	0.000	0.998	0.002
S52.51 Fracture of lower end of radius (open)	0.002	0.998	0.000
S52.5 Fracture of lower end of radius	0.002	0.998	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.998	0.002
H51 Other disorders of binocular movement	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.998	0.002
H44.5 Degenerated conditions of globe	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.998	0.002
N80.9 Endometriosis, unspecified	0.002	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
S52.31 Fracture of shaft of radius (open)	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
H44.6 Retained (old) intraocular foreign body, magnetic	0.002	0.998	0.000
H44.3 Other degenerative disorders of globe	0.002	0.998	0.000
N43.1 Infected hydrocele	0.000	0.998	0.002
I49 Other cardiac arrhythmias	0.002	0.998	0.000
S52.71 Multiple fractures of forearm (open)	0.002	0.998	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.002	0.998	0.000
H52.3 Anisometropia and aniseikonia	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.998	0.002
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.998	0.002
C92.5 Acute myelomonocytic leukaemia	0.000	0.998	0.002
C92.3 Myeloid sarcoma	0.000	0.998	0.002
C92.2 Subacute myeloid leukaemia	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
Z52 Donors of organs and tissues	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
H51.2 Internuclear ophthalmoplegia	0.002	0.998	0.000
H44.9 Disorder of globe, unspecified	0.002	0.998	0.000
T13.1 Open wound of lower limb, level unspecified	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
S52.81 Fracture of other parts of forearm (open)	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
Q12.0 Congenital cataract	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M47.12 Other spondylosis with myelopathy (Cervical region)	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.000	0.998	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
D48.1 Connective and other soft tissue	0.002	0.998	0.000
H51.9 Disorder of binocular movement, unspecified	0.002	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.002	0.998	0.000
H51.1 Convergence insufficiency and excess	0.002	0.998	0.000
H51.0 Palsy of conjugate gaze	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
N43.2 Other hydrocele	0.000	0.998	0.002
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.998	0.002
R50.8 Other specified fever	0.000	0.998	0.002
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.000	0.998	0.002
Z52.8 Donor of other organs and tissues	0.000	0.998	0.002
B16 Acute hepatitis B	0.000	0.998	0.002
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.000	0.998	0.002
H44.4 Hypotony of eye	0.001	0.998	0.000
Z52.9 Donor of unspecified organ or tissue	0.000	0.998	0.002
Z52.7 Heart donor	0.000	0.998	0.002
Z52.6 Liver donor	0.000	0.998	0.002
Z52.5 Cornea donor	0.000	0.998	0.002
Z52.1 Skin donor	0.000	0.998	0.002
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
S52.30 Fracture of shaft of radius (closed)	0.001	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.002	0.998	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
H44.8 Other disorders of globe	0.001	0.998	0.000
Z99.8 Dependence on other enabling machines and devices	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.001
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.001
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.001
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.001
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
H44.0 Purulent endophthalmitis	0.001	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.998	0.002
G95 Other diseases of spinal cord	0.002	0.998	0.000
K58 Irritable bowel syndrome	0.000	0.998	0.002
C24.0 Extrahepatic bile duct	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.001
T13 Other injuries of lower limb, level unspecified	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.001
T13.0 Superficial injury of lower limb, level unspecified	0.001	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.998	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.998	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.998	0.001
C83.3 Large cell (diffuse)	0.001	0.998	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.001	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.001
M77.47 Metatarsalgia-Ankle/Foot	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.001	0.999	0.000
G60.3 Idiopathic progressive neuropathy	0.000	0.999	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.999	0.001
G60.1 Refsum's disease	0.000	0.999	0.001
Z52.2 Bone donor	0.000	0.999	0.001
K61.3 Ischiorectal abscess	0.000	0.999	0.001
K86.1 Other chronic pancreatitis	0.001	0.999	0.000
W20.0 Home	0.000	0.999	0.001
T09 Other injuries of spine and trunk, level unspecified	0.001	0.999	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.999	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.999	0.001
I51.0 Cardiac septal defect, acquired	0.001	0.999	0.000
T09.3 Injury of spinal cord, level unspecified	0.001	0.999	0.000
Z99.3 Dependence on wheelchair	0.001	0.999	0.000
G95.9 Disease of spinal cord, unspecified	0.001	0.999	0.000
O33.9 Maternal care for disproportion, unspecified	0.000	0.999	0.001
S70.9 Superficial injury of hip and thigh, unspecified	0.001	0.999	0.000
Z52.3 Bone marrow donor	0.000	0.999	0.001
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
D40.0 Prostate	0.000	0.999	0.001
M20.4 Other hammer toe(s) (acquired)	0.000	0.999	0.001
S27.3 Other injuries of lung	0.000	0.999	0.001
S27.1 Traumatic haemothorax	0.000	0.999	0.001
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.999	0.001
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.999	0.001
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.999	0.001
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.999	0.001
T13.9 Unspecified injury of lower limb, level unspecified	0.001	0.999	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.001	0.999	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.001	0.999	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.001	0.999	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.001	0.999	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.001	0.999	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.001	0.999	0.000
C91 Lymphoid leukaemia	0.000	0.999	0.001
F30.1 Mania without psychotic symptoms	0.001	0.999	0.000
G70.0 Myasthenia gravis	0.001	0.999	0.000
H52.6 Other disorders of refraction	0.001	0.999	0.000
H52.5 Disorders of accommodation	0.001	0.999	0.000
H52.4 Presbyopia	0.001	0.999	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.999	0.001
F30.8 Other manic episodes	0.001	0.999	0.000
O42 Premature rupture of membranes	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
H01.8 Other specified inflammation of eyelid	0.001	0.999	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.001	0.999	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.001	0.999	0.000
O32.4 Maternal care for high head at term	0.000	0.999	0.001
O42.9 Premature rupture of membranes, unspecified	0.001	0.999	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.999	0.001
S27.7 Multiple injuries of intrathoracic organs	0.000	0.999	0.001
S27.6 Injury of pleura	0.000	0.999	0.001
S27.5 Injury of thoracic trachea	0.000	0.999	0.001
S27.4 Injury of bronchus	0.000	0.999	0.001
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.999	0.001
C91.9 Lymphoid leukaemia, unspecified	0.000	0.999	0.001
C91.4 Hairy-cell leukaemia	0.000	0.999	0.001
F30.0 Hypomania	0.001	0.999	0.000
H05.2 Exophthalmic conditions	0.000	0.999	0.001
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
H52.2 Astigmatism	0.001	0.999	0.000
S05.1 Contusion of eyeball and orbital tissues	0.001	0.999	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.001	0.999	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.001	0.999	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.001	0.999	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.001	0.999	0.000
T09.1 Open wound of trunk, level unspecified	0.001	0.999	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
C91.5 Adult T-cell leukaemia	0.000	0.999	0.001
E04.0 Non-toxic diffuse goitre	0.001	0.999	0.000
G95.0 Syringomyelia and syringobulbia	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.999	0.001
O36.9 Maternal care for foetal problem, unspecified	0.000	0.999	0.001
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.999	0.001
V17.4 Driver injured in traffic accident	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.999	0.001
C67.4 Posterior wall of bladder	0.000	0.999	0.001
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.999	0.001
T09.9 Unspecified injury of trunk, level unspecified	0.001	0.999	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.001	0.999	0.000
Z99.1 Dependence on respirator	0.001	0.999	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.999	0.001
C91.7 Other lymphoid leukaemia	0.000	0.999	0.001
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.999	0.001
C91.3 Prolymphocytic leukaemia	0.000	0.999	0.001
C91.2 Subacute lymphocytic leukaemia	0.000	0.999	0.001
H05.9 Disorder of orbit, unspecified	0.000	0.999	0.001
H49.8 Other paralytic strabismus	0.001	0.999	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.999	0.000
T09.0 Superficial injury of trunk, level unspecified	0.001	0.999	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.001	0.999	0.000
C18.7 Sigmoid colon	0.000	0.999	0.001
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.999	0.001
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.999	0.001
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.000	0.999	0.001
H49 Paralytic strabismus	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations