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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7561317
log Bayes Factor = 7.75616
Chromosome 2   position 644,953  (GRCh37) Explore rs7561317 on Ensembl!
Variant rs7561317 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E66.9 Obesity, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E66 Obesity
0.000 0.000 1.000
E11.9 Without complications
0.000 0.001 0.999
E66.8 Other obesity
0.000 0.002 0.998
E11.4 With neurological complications
0.000 0.006 0.994
E10-E14 Diabetes mellitus
0.000 0.029 0.971
E11.2 With renal complications
0.000 0.030 0.970
E65-E68 Obesity and other hyperalimentation
0.000 0.044 0.956
E11.3 With ophthalmic complications
0.000 0.058 0.942
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.094 0.906
E10 Insulin-dependent diabetes mellitus
0.000 0.126 0.874
E11.5 With peripheral circulatory complications
0.000 0.150 0.850
E66.0 Obesity due to excess calories
0.000 0.202 0.798
E11.8 With unspecified complications
0.000 0.204 0.796
E10.9 Without complications
0.000 0.212 0.788
E65 Localised adiposity
0.000 0.213 0.787
E14 Unspecified diabetes mellitus
0.000 0.238 0.762
E11.7 With multiple complications
0.000 0.283 0.717
E66.1 Drug-induced obesity
0.000 0.283 0.717
E10.4 With neurological complications
0.000 0.291 0.709
E10.2 With renal complications
0.000 0.296 0.704
E12 Malnutrition-related diabetes mellitus
0.000 0.304 0.696
E10.0 With coma
0.000 0.305 0.694
E10.8 With unspecified complications
0.000 0.306 0.694
E67 Other hyperalimentation
0.000 0.314 0.685
E68 Sequelae of hyperalimentation
0.000 0.314 0.685
E14.3 With ophthalmic complications
0.000 0.318 0.682
E11.1 With ketoacidosis
0.000 0.329 0.670
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.339 0.661
E11.6 With other specified complications
0.000 0.354 0.646
E13 Other specified diabetes mellitus
0.000 0.356 0.644
E10.5 With peripheral circulatory complications
0.000 0.369 0.631
E10.7 With multiple complications
0.000 0.373 0.627
E10.6 With other specified complications
0.000 0.402 0.598
E11.0 With coma
0.000 0.407 0.592
E50-E64 Other nutritional deficiencies
0.000 0.412 0.588
E10.3 With ophthalmic complications
0.000 0.451 0.549
E14.8 With unspecified complications
0.000 0.452 0.548
E14.7 With multiple complications
0.000 0.454 0.546
E14.6 With other specified complications
0.000 0.454 0.546
E14.5 With peripheral circulatory complications
0.000 0.454 0.546
E14.2 Withrenal complications
0.000 0.454 0.546
E14.1 With ketoacidosis
0.000 0.454 0.546
E14.0 With coma
0.000 0.454 0.546
E61 Deficiency of other nutrient elements
0.000 0.464 0.536
E61.1 Iron deficiency
0.000 0.497 0.503
E12.9 Without complications
0.000 0.501 0.499
E12.8 With unspecified complications
0.000 0.501 0.499
E12.7 With multiple complications
0.000 0.501 0.499
E12.6 With other specified complications
0.000 0.501 0.499
E12.5 With peripheral circulatory complications
0.000 0.501 0.499
E12.4 With neurological complications
0.000 0.501 0.499
E12.3 With ophthalmic complications
0.000 0.501 0.499
E12.2 With renal complications
0.000 0.501 0.499
E12.1 With ketoacidosis
0.000 0.501 0.499
E12.0 With coma
0.000 0.501 0.499
E67.8 Other specified hyperalimentation
0.000 0.508 0.491
E67.3 Hypervitaminosis D
0.000 0.508 0.491
E67.2 Megavitamin-B6 syndrome
0.000 0.508 0.491
E67.1 Hypercarotenaemia
0.000 0.508 0.491
E67.0 Hypervitaminosis A
0.000 0.508 0.491
E40-E46 Malnutrition
0.000 0.515 0.484
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.523 0.477
E14.4 With neurological complications
0.000 0.530 0.470
E13.8 With unspecified complications
0.000 0.538 0.462
E13.7 With multiple complications
0.000 0.538 0.462
E13.6 With other specified complications
0.000 0.538 0.462
E13.5 With peripheral circulatory complications
0.000 0.538 0.462
E13.4 With neurological complications
0.000 0.538 0.462
E13.3 With ophthalmic complications
0.000 0.538 0.462
E13.2 With renal complications
0.000 0.538 0.462
E13.1 With ketoacidosis
0.000 0.538 0.462
E13.0 With coma
0.000 0.538 0.462
E14.9 Without complications
0.000 0.539 0.461
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.578 0.422
E63 Other nutritional deficiencies
0.000 0.578 0.422
E56 Other vitamin deficiencies
0.000 0.578 0.422
E50 Vitamin A deficiency
0.000 0.578 0.422
E60 Dietary zinc deficiency
0.000 0.578 0.422
E59 Dietary selenium deficiency
0.000 0.578 0.422
E58 Dietary calcium deficiency
0.000 0.578 0.422
E54 Ascorbic acid deficiency
0.000 0.578 0.422
E52 Niacin deficiency [pellagra]
0.000 0.578 0.422
E13.9 Without complications
0.000 0.590 0.410
E51 Thiamine deficiency
0.000 0.600 0.400
E61.9 Deficiency of nutrient element, unspecified
0.000 0.616 0.384
E61.8 Deficiency of other specified nutrient elements
0.000 0.616 0.384
E61.7 Deficiency of multiple nutrient elements
0.000 0.616 0.384
E61.6 Vanadium deficiency
0.000 0.616 0.384
E61.5 Molybdenum deficiency
0.000 0.616 0.384
E61.4 Chromium deficiency
0.000 0.616 0.384
E61.3 Manganese deficiency
0.000 0.616 0.384
E61.0 Copper deficiency
0.000 0.616 0.384
E61.2 Magnesium deficiency
0.000 0.637 0.363
I10 Essential (primary) hypertension
0.000 0.649 0.351
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.652 0.347
E45 Retarded development following protein-energy malnutrition
0.000 0.652 0.347
E43 Unspecified severe protein-energy malnutrition
0.000 0.652 0.347
E42 Marasmic kwashiorkor
0.000 0.652 0.347
E41 Nutritional marasmus
0.000 0.652 0.347
E40 Kwashiorkor
0.000 0.652 0.347
E15 Nondiabetic hypoglycaemic coma
0.000 0.658 0.342
E10.1 With ketoacidosis
0.000 0.684 0.316
E55 Vitamin D deficiency
0.000 0.695 0.305
E50.9 Vitamin A deficiency, unspecified
0.000 0.697 0.302
E50.8 Other manifestations of vitamin A deficiency
0.000 0.697 0.302
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.697 0.302
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.697 0.302
E50.5 Vitamin A deficiency with night blindness
0.000 0.697 0.302
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.697 0.302
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.697 0.302
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.697 0.302
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.697 0.302
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.697 0.302
E56.9 Vitamin deficiency, unspecified
0.000 0.697 0.302
E56.8 Deficiency of other vitamins
0.000 0.697 0.302
E56.1 Deficiency of vitamin K
0.000 0.697 0.302
E56.0 Deficiency of vitamin E
0.000 0.697 0.302
E63.9 Nutritional deficiency, unspecified
0.000 0.697 0.302
E63.8 Other specified nutritional deficiencies
0.000 0.697 0.302
E63.1 Imbalance of constituents of food intake
0.000 0.697 0.302
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.697 0.302
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.697 0.302
E64.8 Sequelae of other nutritional deficiencies
0.000 0.697 0.302
E64.3 Sequelae of rickets
0.000 0.697 0.302
E64.2 Sequelae of vitamin C deficiency
0.000 0.697 0.302
E64.1 Sequelae of vitamin A deficiency
0.000 0.697 0.302
E64.0 Sequelae of protein-energy malnutrition
0.000 0.697 0.302
E51.9 Thiamine deficiency, unspecified
0.000 0.713 0.287
E51.8 Other manifestations of thiamine deficiency
0.000 0.713 0.287
E51.1 Beriberi
0.000 0.713 0.287
E51.2 Wernicke's encephalopathy
0.000 0.735 0.265
E44.1 Mild protein-energy malnutrition
0.000 0.751 0.249
E44.0 Moderate protein-energy malnutrition
0.000 0.751 0.249
E55.0 Rickets, active
0.000 0.781 0.219
E53 Deficiency of other B group vitamins
0.001 0.786 0.213
E46 Unspecified protein-energy malnutrition
0.001 0.817 0.182
E16 Other disorders of pancreatic internal secretion
0.000 0.831 0.169
I10-I15 Hypertensive diseases
0.000 0.834 0.166
E53.1 Pyridoxine deficiency
0.001 0.846 0.153
E53.0 Riboflavin deficiency
0.001 0.846 0.153
I15 Secondary hypertension
0.000 0.869 0.130
I12 Hypertensive renal disease
0.000 0.872 0.128
E53.9 Vitamin B deficiency, unspecified
0.001 0.873 0.127
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.879 0.121
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.879 0.121
E16.4 Abnormal secretion of gastrin
0.000 0.879 0.121
E16.3 Increased secretion of glucagon
0.000 0.879 0.121
I13 Hypertensive heart and renal disease
0.000 0.881 0.119
E16.1 Other hypoglycaemia
0.000 0.889 0.110
I15.1 Hypertension secondary to other renal disorders
0.000 0.894 0.106
I12.9 Hypertensive renal disease without renal failure
0.000 0.894 0.106
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.895 0.105
E55.9 Vitamin D deficiency, unspecified
0.000 0.898 0.102
I11 Hypertensive heart disease
0.000 0.898 0.102
I15.8 Other secondary hypertension
0.000 0.906 0.094
I15.2 Hypertension secondary to endocrine disorders
0.000 0.906 0.094
I15.0 Renovascular hypertension
0.000 0.906 0.094
I15.9 Seconday hypertension, unspecified
0.000 0.907 0.092
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.914 0.085
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.914 0.085
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.914 0.085
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.914 0.085
I12.0 Hypertensive renal disease with renal failure
0.000 0.918 0.082
G56.0 Carpal tunnel syndrome
0.000 0.926 0.074
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.926 0.074
I84.6 Residual haemorrhoidal skin tags
0.000 0.932 0.068
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.945 0.055
E00-E07 Disorders of thyroid gland
0.000 0.961 0.039
E16.2 Hypoglycaemia, unspecified
0.000 0.966 0.033
J22 Unspecified acute lower respiratory infection
0.000 0.969 0.031
Z86.4 Personal history of psychoactive substance abuse
0.000 0.971 0.029
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.972 0.028
E00 Congenital iodine-deficiency syndrome
0.000 0.972 0.028
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.972 0.028
E53.8 Deficiency of other specified B group vitamins
0.001 0.973 0.026
E07 Other disorders of thyroid
0.000 0.975 0.025
E20-E35 Disorders of other endocrine glands
0.006 0.977 0.016
G56 Mononeuropathies of upper limb
0.000 0.979 0.021
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.980 0.020
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.980 0.020
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.980 0.020
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.980 0.020
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.980 0.020
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.980 0.020
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.980 0.020
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.980 0.020
O48 Prolonged pregnancy
0.020 0.980 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.981 0.019
E07.1 Dyshormogenetic goitre
0.000 0.982 0.018
E07.0 Hypersecretion of calcitonin
0.000 0.982 0.018
E35 Disorders of endocrine glands in diseases classified elsewhere
0.005 0.983 0.012
E32 Diseases of thymus
0.005 0.983 0.012
E31 Polyglandular dysfunction
0.005 0.983 0.012
E30 Disorders of puberty, not elsewhere classified
0.005 0.983 0.012
E06 Thyroiditis
0.000 0.984 0.016
E34 Other endocrine disorders
0.003 0.984 0.013
K76.8 Other specified diseases of liver
0.016 0.984 0.000
G56.8 Other mononeuropathies of upper limb
0.000 0.984 0.016
E20 Hypoparathyroidism
0.004 0.984 0.011
G56.3 Lesion of radial nerve
0.000 0.984 0.016
E25 Adrenogenital disorders
0.005 0.984 0.010
E26 Hyperaldosteronism
0.005 0.985 0.011
G56.1 Other lesions of median nerve
0.000 0.985 0.015
E29 Testicular dysfunction
0.004 0.985 0.010
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.985 0.014
G59.0 Diabetic mononeuropathy
0.000 0.986 0.014
G56.4 Causalgia
0.000 0.986 0.014
E07.8 Other specified disorders of thyroid
0.000 0.986 0.014
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.986 0.014
E28 Ovarian dysfunction
0.005 0.986 0.009
E24 Cushing's syndrome
0.005 0.986 0.008
I85.9 Oesophageal varices without bleeding
0.000 0.987 0.013
E23 Hypofunction and other disorders of pituitary gland
0.008 0.987 0.006
S83.2 Tear of meniscus, current
0.000 0.987 0.013
E34.9 Endocrine disorder, unspecified
0.002 0.987 0.011
E22 Hyperfunction of pituitary gland
0.004 0.987 0.008
I85 Oesophageal varices
0.000 0.988 0.012
I84.4 External haemorrhoids with other complications
0.000 0.988 0.012
E30.9 Disorder of puberty, unspecified
0.003 0.988 0.009
E30.8 Other disorders of puberty
0.003 0.988 0.009
E30.1 Precocious puberty
0.003 0.988 0.009
E30.0 Delayed puberty
0.003 0.988 0.009
E31.9 Polyglandular dysfunction, unspecified
0.003 0.988 0.009
E31.8 Other polyglandular dysfunction
0.003 0.988 0.009
E31.1 Polyglandular hyperfunction
0.003 0.988 0.009
E31.0 Autoimmune polyglandular failure
0.003 0.988 0.009
E32.9 Disease of thymus, unspecified
0.003 0.988 0.009
E32.8 Other diseases of thymus
0.003 0.988 0.009
E32.1 Abscess of thymus
0.003 0.988 0.009
E32.0 Persistent hyperplasia of thymus
0.003 0.988 0.009
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.003 0.988 0.009
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.003 0.988 0.009
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.003 0.988 0.009
E06.5 Other chronic thyroiditis
0.000 0.988 0.012
E06.4 Drug-induced thyroiditis
0.000 0.988 0.012
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.988 0.012
E06.1 Subacute thyroiditis
0.000 0.988 0.012
E06.0 Acute thyroiditis
0.000 0.988 0.012
E34.5 Androgen resistance syndrome
0.003 0.988 0.009
E34.4 Constitutional tall stature
0.003 0.988 0.009
E34.3 Short stature, not elsewhere classified
0.003 0.988 0.009
E34.2 Ectopic hormone secretion, not elsewhere classified
0.003 0.988 0.009
E34.1 Other hypersecretion of intestinal hormones
0.003 0.988 0.009
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.988 0.012
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.988 0.012
E34.0 Carcinoid syndrome
0.002 0.988 0.010
I84 Haemorrhoids
0.000 0.988 0.012
E20.8 Other hypoparathyroidism
0.003 0.988 0.008
E20.1 Pseudohypoparathyroidism
0.003 0.988 0.008
E20.0 Idiopathic hypoparathyroidism
0.003 0.988 0.008
N80.9 Endometriosis, unspecified
0.012 0.988 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.000 0.989 0.011
E25.9 Adrenogenital disorder, unspecified
0.004 0.989 0.008
E25.8 Other adrenogenital disorders
0.004 0.989 0.008
E26.9 Hyperaldosteronism, unspecified
0.003 0.989 0.008
E26.8 Other hyperaldosteronism
0.003 0.989 0.008
E26.1 Secondary hyperaldosteronism
0.003 0.989 0.008
E34.8 Other specified endocrine disorders
0.003 0.989 0.009
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.989 0.011
I89.0 Lymphoedema, not elsewhere classified
0.000 0.989 0.011
I80 Phlebitis and thrombophlebitis
0.000 0.989 0.011
E20.9 Hypoparathyroidism, unspecified
0.003 0.989 0.008
E70-E90 Metabolic disorders
0.000 0.989 0.011
E29.9 Testicular dysfunction, unspecified
0.003 0.989 0.008
E29.8 Other testicular dysfunction
0.003 0.989 0.008
E29.0 Testicular hyperfunction
0.003 0.989 0.008
J20-J22 Other acute lower respiratory infections
0.000 0.989 0.011
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.005 0.989 0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.005 0.990 0.006
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.990 0.010
I82 Other venous embolism and thrombosis
0.000 0.990 0.010
E26.0 Primary hyperaldosteronism
0.004 0.990 0.007
E28.9 Ovarian dysfunction, unspecified
0.003 0.990 0.007
E28.8 Other ovarian dysfunction
0.003 0.990 0.007
E28.1 Androgen excess
0.003 0.990 0.007
E28.0 Oestrogen excess
0.003 0.990 0.007
E24.8 Other Cushing's syndrome
0.004 0.990 0.006
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.004 0.990 0.006
E24.3 Ectopic ACTH syndrome
0.004 0.990 0.006
E24.1 Nelson's syndrome
0.004 0.990 0.006
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.000 0.990 0.010
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.990 0.010
E24.0 Pituitary-dependent Cushing's disease
0.004 0.990 0.006
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.990 0.010
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.006 0.990 0.004
E23.1 Drug-induced hypopituitarism
0.006 0.990 0.004
E23.0 Hypopituitarism
0.009 0.990 0.001
I84.0 Internal thrombosed haemorrhoids
0.000 0.991 0.009
I82.8 Embolism and thrombosis of other specified veins
0.000 0.991 0.009
I85.0 Oesophageal varices with bleeding
0.000 0.991 0.009
E22.9 Hyperfunction of pituitary gland, unspecified
0.003 0.991 0.006
E22.8 Other hyperfunction of pituitary gland
0.003 0.991 0.006
E24.2 Drug-induced Cushing's syndrome
0.005 0.991 0.005
E23.2 Diabetes insipidus
0.007 0.991 0.002
I81 Portal vein thrombosis
0.000 0.991 0.009
E23.7 Disorder of pituitary gland, unspecified
0.005 0.991 0.004
E27 Other disorders of adrenal gland
0.005 0.991 0.004
E24.9 Cushing's syndrome, unspecified
0.004 0.991 0.005
E85 Amyloidosis
0.000 0.991 0.009
N99.0 Postprocedural renal failure
0.000 0.991 0.009
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.991 0.009
E03 Other hypothyroidism
0.000 0.991 0.009
E23.6 Other disorders of pituitary gland
0.004 0.991 0.005
E29.1 Testicular hypofunction
0.003 0.991 0.006
H54.7 Unspecified visual loss
0.000 0.991 0.009
E28.3 Primary ovarian failure
0.004 0.991 0.005
N99.5 Malfunction of external stoma of urinary tract
0.000 0.991 0.009
I89.1 Lymphangitis
0.000 0.991 0.009
E28.2 Polycystic ovarian syndrome
0.002 0.991 0.006
I86 Varicose veins of other sites
0.000 0.991 0.009
N99.2 Postprocedural adhesions of vagina
0.000 0.991 0.008
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.992 0.008
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.992 0.008
I84.1 Internal haemorrhoids with other complications
0.000 0.992 0.008
E22.1 Hyperprolactinaemia
0.004 0.992 0.005
E22.0 Acromegaly and pituitary gigantism
0.003 0.992 0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.002 0.992 0.006
G43.1 Migraine with aura [classical migraine]
0.000 0.992 0.008
E06.3 Autoimmune thyroiditis
0.000 0.992 0.008
E84 Cystic fibrosis
0.000 0.992 0.008
E79 Disorders of purine and pyrimidine metabolism
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.000 0.992 0.008
E76 Disorders of glycosaminoglycan metabolism
0.000 0.992 0.008
E72 Other disorders of amino-acid metabolism
0.000 0.992 0.008
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.992 0.008
E70 Disorders of aromatic amino-acid metabolism
0.000 0.992 0.008
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.992 0.008
E06.9 Thyroiditis, unspecified
0.001 0.992 0.007
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.992 0.008
E73 Lactose intolerance
0.000 0.992 0.008
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.992 0.008
E21.4 Other specified disorders of parathyroid gland
0.004 0.992 0.004
E21.2 Other hyperparathyroidism
0.004 0.992 0.004
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.992 0.008
N99.1 Postprocedural urethral stricture
0.000 0.992 0.008
E05.8 Other thyrotoxicosis
0.000 0.992 0.008
E05.5 Thyroid crisis or storm
0.000 0.992 0.008
E05.4 Thyrotoxicosis factitia
0.000 0.992 0.008
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.992 0.008
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.992 0.008
J21 Acute bronchiolitis
0.000 0.992 0.008
G35 Multiple sclerosis
0.008 0.992 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.992 0.008
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.992 0.008
I82.3 Embolism and thrombosis of renal vein
0.000 0.992 0.007
I82.1 Thrombophlebitis migrans
0.000 0.992 0.007
I82.0 Budd-Chiari syndrome
0.000 0.992 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.004 0.992 0.004
I86.8 Varicose veins of other specified sites
0.000 0.992 0.007
G40-G47 Episodic and paroxysmal disorders
0.000 0.992 0.008
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.000 0.993 0.007
G47.3 Sleep apnoea
0.000 0.993 0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.003 0.993 0.004
E85.4 Organ-limited amyloidosis
0.000 0.993 0.007
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.000 0.993 0.007
G43 Migraine
0.000 0.993 0.007
G59.8 Other mononeuropathies in diseases classified elsewhere
0.000 0.993 0.007
N99.3 Prolapse of vaginal vault after hysterectomy
0.000 0.993 0.007
E85.9 Amyloidosis, unspecified
0.000 0.993 0.007
E74 Other disorders of carbohydrate metabolism
0.000 0.993 0.007
J20 Acute bronchitis
0.000 0.993 0.007
I88 Nonspecific lymphadenitis
0.001 0.993 0.006
E27.5 Adrenomedullary hyperfunction
0.004 0.993 0.003
E27.0 Other adrenocortical overactivity
0.004 0.993 0.003
E85.8 Other amyloidosis
0.000 0.993 0.007
E85.3 Secondary systemic amyloidosis
0.000 0.993 0.007
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.993 0.007
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E03.5 Myxoedema coma
0.000 0.993 0.007
E03.4 Atrophy of thyroid (acquired)
0.000 0.993 0.007
E03.3 Postinfectious hypothyroidism
0.000 0.993 0.007
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.993 0.007
E27.3 Drug-induced adrenocortical insufficiency
0.004 0.993 0.003
I82.2 Embolism and thrombosis of vena cava
0.000 0.993 0.007
G47 Sleep disorders
0.000 0.993 0.007
E87.5 Hyperkalaemia
0.000 0.993 0.007
E27.9 Disorder of adrenal gland, unspecified
0.005 0.993 0.002
G44 Other headache syndromes
0.000 0.993 0.007
Chapter IX Diseases of the circulatory system
0.000 0.993 0.007
I86.2 Pelvic varices
0.000 0.993 0.006
E27.8 Other specified disorders of adrenal gland
0.004 0.993 0.002
E27.2 Addisonian crisis
0.003 0.994 0.003
I87 Other disorders of veins
0.000 0.994 0.006
I86.3 Vulval varices
0.000 0.994 0.006
I86.0 Sublingual varices
0.000 0.994 0.006
I73.9 Peripheral vascular disease, unspecified
0.000 0.994 0.006
I50.0 Congestive heart failure
0.000 0.994 0.006
E78.8 Other disorders of lipoprotein metabolism
0.000 0.994 0.006
G56.2 Lesion of ulnar nerve
0.000 0.994 0.006
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.994 0.006
G43.8 Other migraine
0.000 0.994 0.006
I86.4 Gastric varices
0.000 0.994 0.006
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.994 0.006
G45.3 Amaurosis fugax
0.000 0.994 0.006
N99.8 Other postprocedural disorders of genito-urinary system
0.000 0.994 0.006
G44.2 Tension-type headache
0.000 0.994 0.006
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.994 0.006
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.994 0.006
E70.3 Albinism
0.000 0.994 0.006
E70.2 Disorders of tyrosine metabolism
0.000 0.994 0.006
E70.1 Other hyperphenylalaninaemias
0.000 0.994 0.006
E70.0 Classical phenylketonuria
0.000 0.994 0.006
E71.3 Disorders of fatty-acid metabolism
0.000 0.994 0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.994 0.006
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.994 0.006
E71.0 Maple-syrup-urine disease
0.000 0.994 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.994 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.994 0.006
E72.5 Disorders of glycine metabolism
0.000 0.994 0.006
E72.4 Disorders of ornithine metabolism
0.000 0.994 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.994 0.006
E72.2 Disorders of urea cycle metabolism
0.000 0.994 0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.994 0.006
E72.0 Disorders of amino-acid transport
0.000 0.994 0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.994 0.006
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.994 0.006
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.994 0.006
E76.2 Other mucopolysaccharidoses
0.000 0.994 0.006
E76.1 Mucopolysaccharidosis, type II
0.000 0.994 0.006
E76.0 Mucopolysaccharidosis, type I
0.000 0.994 0.006
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.994 0.006
E77.8 Other disorders of glycoprotein metabolism
0.000 0.994 0.006
E77.1 Defects in glycoprotein degradation
0.000 0.994 0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.994 0.006
E78.5 Hyperlipidaemia, unspecified
0.000 0.994 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.994 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.994 0.006
E79.1 Lesch-Nyhan syndrome
0.000 0.994 0.006
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.000 0.994 0.006
E84.8 Cystic fibrosis with other manifestations
0.000 0.994 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.994 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.994 0.006
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.994 0.006
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.994 0.006
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.994 0.006
E27.4 Other and unspecified adrenocortical insufficiency
0.004 0.994 0.002
G45.2 Multiple and bilateral precerebral artery syndromes
0.000 0.994 0.006
K60.1 Chronic anal fissure
0.000 0.994 0.006
G45.0 Vertebro-basilar artery syndrome
0.000 0.994 0.006
E03.1 Congenital hypothyroidism without goitre
0.000 0.994 0.006
E73.8 Other lactose intolerance
0.000 0.994 0.006
E73.1 Secondary lactase deficiency
0.000 0.994 0.006
E73.0 Congenital lactase deficiency
0.000 0.994 0.006
E78.1 Pure hyperglyceridaemia
0.000 0.994 0.006
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.994 0.006
Z50.1 Other physical therapy
0.000 0.994 0.006
G41 Status epilepticus
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.000 0.994 0.006
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.994 0.006
E75.3 Sphingolipidosis, unspecified
0.000 0.994 0.006
E75.2 Other sphingolipidosis
0.000 0.994 0.006
E75.1 Other gangliosidosis
0.000 0.994 0.006
E75.0 GM2 gangliosidosis
0.000 0.994 0.006
E73.9 Lactose intolerance, unspecified
0.000 0.994 0.006
H54 Blindness and low vision
0.000 0.994 0.006
E78.0 Pure hypercholesterolaemia
0.000 0.994 0.006
E21.3 Hyperparathyroidism, unspecified
0.002 0.994 0.004
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.994 0.006
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.994 0.006
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.994 0.006
I84.3 External thrombosed haemorrhoids
0.000 0.994 0.006
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.994 0.006
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.994 0.006
E78.6 Lipoprotein deficiency
0.000 0.994 0.006
E78.3 Hyperchylomicronaemia
0.000 0.994 0.006
G43.0 Migraine without aura [common migraine]
0.000 0.994 0.006
E75.5 Other lipid storage disorders
0.000 0.994 0.005
H54.9 Unspecified visual impairment (binocular)
0.000 0.994 0.006
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.000 0.994 0.006
E27.1 Primary adrenocortical insufficiency
0.003 0.994 0.003
G43.3 Complicated migraine
0.000 0.994 0.005
G43.2 Status migrainosus
0.000 0.994 0.005
J21.9 Acute bronchiolitis, unspecified
0.000 0.994 0.005
E78.4 Other hyperlipidaemia
0.000 0.994 0.005
G45.1 Carotid artery syndrome (hemispheric)
0.000 0.994 0.005
G44.4 Drug-induced headache, not elsewhere classified
0.000 0.995 0.005
E21.0 Primary hyperparathyroidism
0.005 0.995 0.001
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.995 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.995 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.995 0.005
E74.2 Disorders of galactose metabolism
0.000 0.995 0.005
E74.1 Disorders of fructose metabolism
0.000 0.995 0.005
E74.0 Glycogen storage disease
0.000 0.995 0.005
J20.7 Acute bronchitis due to echovirus
0.000 0.995 0.005
J20.6 Acute bronchitis due to rhinovirus
0.000 0.995 0.005
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.995 0.005
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.995 0.005
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.995 0.005
J20.2 Acute bronchitis due to streptococcus
0.000 0.995 0.005
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.995 0.005
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.995 0.005
E03.8 Other specified hypothyroidism
0.000 0.995 0.005
I88.8 Other nonspecific lymphadenitis
0.001 0.995 0.005
I88.1 Chronic lymphadenitis, except mesenteric
0.001 0.995 0.005
I88.0 Nonspecific mesenteric lymphadenitis
0.001 0.995 0.005
E88 Other metabolic disorders
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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