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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75911208
log Bayes Factor = 8.932
Chromosome 22   position 39,905,549  (GRCh37) Explore rs75911208 on Ensembl!
Variant rs75911208 is part of Cluster X0283

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.996 0.004 0.000
N10-N16 Renal tubulo-interstitial diseases
0.991 0.009 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.990 0.010 0.000
N18.9 Chronic renal failure, unspecified
0.988 0.012 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.981 0.019 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.980 0.020 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.979 0.021 0.000
N13 Obstructive and reflux uropathy
0.978 0.022 0.000
Y43 Primarily systemic agents
0.978 0.022 0.000
C77.1 Intrathoracic lymph nodes
0.978 0.022 0.000
N18.3 Chronic kidney disease, stage 3
0.977 0.023 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.975 0.025 0.000
L89 Decubitus ulcer
0.969 0.031 0.000
D22 Melanocytic naevi
0.960 0.040 0.000
D10-D36 Benign neoplasms
0.957 0.043 0.000
C79.2 Secondary malignant neoplasm of skin
0.957 0.043 0.000
Y43.3 Other antineoplastic drugs
0.950 0.050 0.000
L89.1 Stage II decubitus ulcer
0.948 0.052 0.000
F30-F39 Mood [affective] disorders
0.948 0.052 0.000
Q60-Q64 Congenital malformations of the urinary system
0.941 0.059 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.940 0.060 0.000
F31 Bipolar affective disorder
0.939 0.061 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.937 0.063 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.937 0.063 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.935 0.065 0.000
E70-E90 Metabolic disorders
0.935 0.065 0.000
N19 Unspecified renal failure
0.931 0.069 0.000
C32 Malignant neoplasm of larynx
0.926 0.074 0.000
L85 Other epidermal thickening
0.926 0.074 0.000
C77.8 Lymph nodes of multiple regions
0.919 0.081 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.919 0.081 0.000
E83 Disorders of mineral metabolism
0.914 0.086 0.000
D22.4 Melanocytic naevi of scalp and neck
0.913 0.087 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.911 0.089 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.911 0.089 0.000
N17 Acute renal failure
0.910 0.090 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.908 0.092 0.000
S70-S79 Injuries to the hip and thigh
0.907 0.093 0.000
N13.8 Other obstructive and reflux uropathy
0.905 0.095 0.000
D11 Benign neoplasm of major salivary glands
0.899 0.101 0.000
C80 Malignant neoplasm without specification of site
0.890 0.110 0.000
F40 Phobic anxiety disorders
0.889 0.111 0.000
Q61 Cystic kidney disease
0.889 0.111 0.000
L60-L75 Disorders of skin appendages
0.889 0.111 0.000
N18.5 Chronic kidney disease, stage 5
0.885 0.115 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.879 0.121 0.000
S79 Other and unspecified injuries of hip and thigh
0.876 0.124 0.000
D36 Benign neoplasm of other and unspecified sites
0.876 0.124 0.000
C34 Malignant neoplasm of bronchus and lung
0.875 0.125 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.874 0.126 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.873 0.127 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.866 0.134 0.000
D22.5 Melanocytic naevi of trunk
0.866 0.134 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.861 0.139 0.000
D32 Benign neoplasm of meninges
0.859 0.141 0.000
L60 Nail disorders
0.855 0.145 0.000
F40.2 Specific (isolated) phobias
0.854 0.146 0.000
V80-V89 Other land transport accidents
0.851 0.149 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.850 0.150 0.000
Y52 Agents primarily affecting the cardiovascular system
0.849 0.151 0.000
N10 Acute tubulo-interstitial nephritis
0.848 0.152 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.848 0.152 0.000
L40-L45 Papulosquamous disorders
0.845 0.155 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.844 0.156 0.000
Y43.4 Immunosuppressive agents
0.841 0.159 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.839 0.161 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.839 0.161 0.000
D11.0 Parotid gland
0.838 0.162 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.837 0.163 0.000
E83.3 Disorders of phosphorus metabolism
0.837 0.163 0.000
F31.9 Bipolar affective disorder, unspecified
0.837 0.163 0.000
Y44 Agents primarily affecting blood constituents
0.835 0.165 0.000
L85.8 Other specified epidermal thickening
0.833 0.167 0.000
Y57 Other and unspecified drugs and medicaments
0.830 0.170 0.000
C34.1 Upper lobe, bronchus or lung
0.829 0.171 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.828 0.172 0.000
S90-S99 Injuries to the ankle and foot
0.827 0.173 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.825 0.175 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.824 0.176 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.823 0.177 0.000
L85.9 Epidermal thickening, unspecified
0.820 0.180 0.000
N17.9 Acute renal failure, unspecified
0.819 0.181 0.000
L91 Hypertrophic disorders of skin
0.818 0.182 0.000
L81 Other disorders of pigmentation
0.818 0.182 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.817 0.183 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.816 0.184 0.000
Q61.2 Polycystic kidney, adult type
0.815 0.185 0.000
E87.5 Hyperkalaemia
0.813 0.187 0.000
S79.9 Unspecified injury of hip and thigh
0.812 0.188 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.812 0.188 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.811 0.189 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.811 0.189 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.808 0.192 0.000
W50-W64 Exposure to animate mechanical forces
0.807 0.193 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.807 0.193 0.000
N13.3 Other and unspecified hydronephrosis
0.805 0.195 0.000
F42 Obsessive-compulsive disorder
0.803 0.197 0.000
L60.0 Ingrowing nail
0.802 0.198 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.801 0.199 0.000
E83.1 Disorders of iron metabolism
0.799 0.201 0.000
T00-T07 Injuries involving multiple body regions
0.799 0.201 0.000
D36.7 Other specified sites
0.796 0.204 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.795 0.204 0.000
C77.0 Lymph nodes of head, face and neck
0.795 0.205 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.793 0.207 0.000
S79.8 Other specified injuries of hip and thigh
0.792 0.208 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.792 0.208 0.000
L89.2 Stage III decubitus ulcer
0.791 0.209 0.000
D16 Benign neoplasm of bone and articular cartilage
0.789 0.211 0.000
X50-X57 Overexertion, travel and privation
0.789 0.211 0.000
Chapter I Certain infectious and parasitic diseases
0.789 0.211 0.000
C32.2 Subglottis
0.787 0.213 0.000
D22.0 Melanocytic naevi of lip
0.787 0.213 0.000
F43 Reaction to severe stress, and adjustment disorders
0.786 0.214 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.786 0.214 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.784 0.216 0.000
E83.4 Disorders of magnesium metabolism
0.784 0.216 0.000
Chapter XXII Codes for special purposes
0.783 0.217 0.000
Y48 Anaesthetics and therapeutic gases
0.781 0.219 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.779 0.221 0.000
N18.2 Chronic kidney disease, stage 2
0.776 0.224 0.000
V20-V29 Motorcycle rider injured in transport accident
0.775 0.225 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.773 0.227 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.773 0.227 0.000
C32.1 Supraglottis
0.772 0.228 0.000
C32.0 Glottis
0.770 0.229 0.000
L50-L54 Urticaria and erythema
0.770 0.230 0.000
L94 Other localised connective tissue disorders
0.770 0.230 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.768 0.232 0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.768 0.232 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.767 0.233 0.000
N18.0 End-stage renal disease
0.766 0.234 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.766 0.234 0.000
N18.4 Chronic kidney disease, stage 4
0.766 0.234 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.765 0.235 0.000
E73 Lactose intolerance
0.765 0.235 0.000
W75-W84 Other accidental threats to breathing
0.765 0.235 0.000
N13.4 Hydroureter
0.764 0.236 0.000
S40-S49 Injuries to the shoulder and upper arm
0.763 0.237 0.000
L89.3 Stage IV decubitus ulcer
0.762 0.238 0.000
E86 Volume depletion
0.762 0.238 0.000
Q50-Q56 Congenital malformations of genital organs
0.760 0.240 0.000
L43 Lichen planus
0.760 0.240 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.758 0.242 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.754 0.246 0.000
X60-X84 Intentional self-harm
0.751 0.249 0.000
C77.4 Inguinal and lower limb lymph nodes
0.750 0.250 0.000
L93 Lupus erythematosus
0.749 0.250 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.749 0.251 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.749 0.251 0.000
C92 Myeloid leukaemia
0.748 0.252 0.000
O00-O08 Pregnancy with abortive outcome
0.747 0.253 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.747 0.253 0.000
F70-F79 Mental retardation
0.747 0.253 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.745 0.255 0.000
E80.4 Gilbert's syndrome
0.745 0.255 0.000
A30-A49 Other bacterial diseases
0.744 0.256 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.742 0.258 0.000
N75 Diseases of Bartholin's gland
0.742 0.258 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.258 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.741 0.259 0.000
Y42.5 Other oestrogens and progestogens
0.740 0.260 0.000
D32.0 Cerebral meninges
0.740 0.260 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.740 0.260 0.000
L91.8 Other hypertrophic disorders of skin
0.740 0.260 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.740 0.260 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.738 0.261 0.000
C32.9 Larynx, unspecified
0.738 0.262 0.000
Q61.3 Polycystic kidney, unspecified
0.735 0.265 0.000
Y43.0 Antiallergic and antiemetic drugs
0.734 0.266 0.000
N18.8 Other chronic renal failure
0.734 0.266 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.734 0.266 0.000
C93 Monocytic leukaemia
0.734 0.266 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.733 0.267 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.732 0.268 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.731 0.269 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.731 0.269 0.000
D60-D64 Aplastic and other anaemias
0.731 0.269 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.729 0.271 0.000
Y00-Y09 Assault
0.728 0.272 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.727 0.272 0.000
E88 Other metabolic disorders
0.726 0.274 0.000
N17.0 Acute renal failure with tubular necrosis
0.726 0.274 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.723 0.277 0.000
E00-E07 Disorders of thyroid gland
0.722 0.278 0.000
Q64 Other congenital malformations of urinary system
0.722 0.278 0.000
C80.9 Malignant neoplasm, unspecified
0.721 0.279 0.000
Y44.2 Anticoagulants
0.720 0.280 0.000
F30 Manic episode
0.719 0.281 0.000
X10-X19 Contact with heat and hot substances
0.718 0.282 0.000
Q00-Q07 Congenital malformations of the nervous system
0.718 0.282 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
N18.1 Chronic kidney disease, stage 1
0.717 0.283 0.000
D22.9 Melanocytic naevi, unspecified
0.716 0.284 0.000
S90 Superficial injury of ankle and foot
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
A41 Other septicaemia
0.715 0.285 0.000
Y59 Other and unspecified vaccines and biological substances
0.714 0.286 0.000
Y58 Bacterial vaccines
0.714 0.286 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.714 0.286 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.714 0.286 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
E87.7 Fluid overload
0.713 0.287 0.000
L70 Acne
0.712 0.288 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.710 0.289 0.000
N15 Other renal tubulo-interstitial diseases
0.710 0.289 0.000
N00-N08 Glomerular diseases
0.710 0.290 0.000
L10-L14 Bullous disorders
0.709 0.290 0.000
D11.9 Major salivary gland, unspecified
0.709 0.291 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.707 0.293 0.000
D31 Benign neoplasm of eye and adnexa
0.707 0.293 0.000
C88 Malignant immunoproliferative diseases
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.703 0.297 0.000
Q35-Q37 Cleft lip and cleft palate
0.703 0.297 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.703 0.297 0.000
C34.3 Lower lobe, bronchus or lung
0.703 0.297 0.000
Q80-Q89 Other congenital malformations
0.702 0.297 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.702 0.298 0.000
L87 Transepidermal elimination disorders
0.702 0.298 0.000
L88 Pyoderma gangrenosum
0.702 0.298 0.000
L86 Keratoderma in diseases classified elsewhere
0.702 0.298 0.000
L80 Vitiligo
0.702 0.298 0.000
Y43.9 Primarily systemic agent, unspecified
0.701 0.299 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.701 0.299 0.000
Y43.6 Enzymes, not elsewhere classified
0.701 0.299 0.000
Y43.5 Acidifying and alkalising agents
0.701 0.299 0.000
Y43.2 Antineoplastic natural products
0.701 0.299 0.000
D30 Benign neoplasm of urinary organs
0.701 0.299 0.000
F60-F69 Disorders of adult personality and behaviour
0.701 0.299 0.000
L81.4 Other melanin hyperpigmentation
0.700 0.300 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.699 0.301 0.000
Q60.0 Renal agenesis, unilateral
0.699 0.301 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.699 0.301 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.699 0.301 0.000
C31 Malignant neoplasm of accessory sinuses
0.699 0.301 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.699 0.301 0.000
C37 Malignant neoplasm of thymus
0.699 0.301 0.000
C33 Malignant neoplasm of trachea
0.699 0.301 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.699 0.301 0.000
L43.9 Lichen planus, unspecified
0.699 0.301 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.699 0.301 0.000
D50-D53 Nutritional anaemias
0.699 0.301 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.698 0.302 0.000
S72 Fracture of femur
0.697 0.303 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.695 0.304 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.695 0.305 0.000
T00 Superficial injuries involving multiple body regions
0.695 0.305 0.000
N72 Inflammatory disease of cervix uteri
0.694 0.306 0.000
E83.5 Disorders of calcium metabolism
0.694 0.306 0.000
D32.9 Meninges, unspecified
0.694 0.306 0.000
L60.2 Onychogryphosis
0.693 0.307 0.000
C81 Hodgkin's disease
0.691 0.309 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.691 0.309 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.690 0.310 0.000
N25-N29 Other disorders of kidney and ureter
0.690 0.310 0.000
Y43.1 Antineoplastic antimetabolites
0.689 0.311 0.000
Y57.8 Other drugs and medicaments
0.689 0.311 0.000
D10 Benign neoplasm of mouth and pharynx
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.688 0.312 0.000
L65 Other nonscarring hair loss
0.688 0.312 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.687 0.313 0.000
S50-S59 Injuries to the elbow and forearm
0.687 0.313 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.686 0.313 0.000
D19 Benign neoplasm of mesothelial tissue
0.686 0.313 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.686 0.313 0.000
C77.9 Lymph node, unspecified
0.685 0.315 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.684 0.316 0.000
Q61.0 Congenital single renal cyst
0.683 0.317 0.000
Y41.0 Sulphonamides
0.683 0.317 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.682 0.318 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.682 0.318 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.681 0.319 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.681 0.319 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.681 0.319 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.680 0.320 0.000
F38 Other mood [affective] disorders
0.679 0.320 0.000
F34 Persistent mood [affective] disorders
0.679 0.320 0.000
F39 Unspecified mood [affective] disorder
0.679 0.320 0.000
Y57.5 X-ray contrast media
0.679 0.321 0.000
F43.1 Posttraumatic stress disorder
0.678 0.322 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.677 0.323 0.000
C09 Malignant neoplasm of tonsil
0.676 0.324 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.675 0.325 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.675 0.325 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.674 0.325 0.000
D26 Other benign neoplasms of uterus
0.674 0.326 0.000
F31.8 Other bipolar affective disorders
0.673 0.327 0.000
F31.7 Bipolar affective disorder, currently in remission
0.673 0.327 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.673 0.327 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.673 0.327 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.673 0.327 0.000
S71 Open wound of hip and thigh
0.673 0.327 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.672 0.328 0.000
T33-T35 Frostbite
0.672 0.328 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.672 0.328 0.000
F48 Other neurotic disorders
0.671 0.328 0.000
F44 Dissociative [conversion] disorders
0.671 0.328 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.671 0.329 0.000
E85 Amyloidosis
0.670 0.330 0.000
E84 Cystic fibrosis
0.670 0.330 0.000
E79 Disorders of purine and pyrimidine metabolism
0.670 0.330 0.000
E77 Disorders of glycoprotein metabolism
0.670 0.330 0.000
E76 Disorders of glycosaminoglycan metabolism
0.670 0.330 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.670 0.330 0.000
E74 Other disorders of carbohydrate metabolism
0.670 0.330 0.000
E72 Other disorders of amino-acid metabolism
0.670 0.330 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.670 0.330 0.000
E70 Disorders of aromatic amino-acid metabolism
0.670 0.330 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.670 0.330 0.000
L81.8 Other specified disorders of pigmentation
0.670 0.330 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.669 0.331 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.669 0.331 0.000
C32.8 Overlapping lesion of larynx
0.664 0.336 0.000
C32.3 Laryngeal cartilage
0.664 0.336 0.000
L85.3 Xerosis cutis
0.664 0.336 0.000
L85.2 Keratosis punctata (palmaris et plantaris)
0.664 0.336 0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.664 0.336 0.000
L85.0 Acquired ichthyosis
0.664 0.336 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.664 0.336 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.663 0.337 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.663 0.337 0.000
L73 Other follicular disorders
0.663 0.337 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.663 0.337 0.000
D11.7 Other major salivary glands
0.663 0.337 0.000
E87.3 Alkalosis
0.662 0.338 0.000
D16.9 Bone and articular cartilage, unspecified
0.662 0.338 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.662 0.338 0.000
S70 Superficial injury of hip and thigh
0.662 0.338 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.661 0.339 0.000
L60.8 Other nail disorders
0.660 0.340 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.659 0.341 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.658 0.342 0.000
Chapter IX Diseases of the circulatory system
0.658 0.342 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.658 0.342 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.658 0.342 0.000
A41.9 Septicaemia, unspecified
0.657 0.343 0.000
L83 Acanthosis nigricans
0.657 0.343 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.656 0.344 0.000
E83.8 Other disorders of mineral metabolism
0.656 0.344 0.000
E83.2 Disorders of zinc metabolism
0.656 0.344 0.000
E83.0 Disorders of copper metabolism
0.656 0.344 0.000
X50 Overexertion and strenuous or repetitive movements
0.655 0.345 0.000
L60.9 Nail disorder, unspecified
0.654 0.346 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
C95 Leukaemia of unspecified cell type
0.653 0.347 0.000
C94 Other leukaemias of specified cell type
0.653 0.347 0.000
C86 Other specified types of T/NK-cell lymphoma
0.653 0.347 0.000
F45 Somatoform disorders
0.653 0.347 0.000
D29 Benign neoplasm of male genital organs
0.652 0.347 0.000
O20 Haemorrhage in early pregnancy
0.652 0.348 0.000
N17.8 Other acute renal failure
0.652 0.348 0.000
N17.2 Acute renal failure with medullary necrosis
0.652 0.348 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.652 0.348 0.000
D35.1 Parathyroid gland
0.652 0.348 0.000
F40.0 Agoraphobia
0.650 0.349 0.000
S78 Traumatic amputation of hip and thigh
0.650 0.350 0.000
S77 Crushing injury of hip and thigh
0.650 0.350 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.650 0.350 0.000
S75 Injury of blood vessels at hip and thigh level
0.650 0.350 0.000
S74 Injury of nerves at hip and thigh level
0.650 0.350 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.650 0.350 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.649 0.351 0.000
C92.1 Chronic myeloid leukaemia
0.649 0.351 0.000
Y54.5 Other diuretics
0.649 0.351 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.648 0.352 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.647 0.353 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.647 0.353 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.646 0.354 0.000
N11 Chronic tubulo-interstitial nephritis
0.646 0.354 0.000
N75.1 Abscess of Bartholin's gland
0.646 0.354 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.646 0.354 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.645 0.355 0.000
D32.1 Spinal meninges
0.644 0.355 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.644 0.356 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.644 0.356 0.000
C34.2 Middle lobe, bronchus or lung
0.644 0.356 0.000
F99-F99 Unspecified mental disorder
0.644 0.356 0.000
E73.9 Lactose intolerance, unspecified
0.644 0.356 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.644 0.356 0.000
C64-C68 Malignant neoplasms of urinary tract
0.642 0.358 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.642 0.358 0.000
I10-I15 Hypertensive diseases
0.642 0.358 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.642 0.358 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.641 0.359 0.000
N76 Other inflammation of vagina and vulva
0.640 0.360 0.000
Q60.2 Renal agenesis, unspecified
0.640 0.360 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.640 0.360 0.000
F40.9 Phobic anxiety disorder, unspecified
0.638 0.362 0.000
F40.8 Other phobic anxiety disorders
0.638 0.362 0.000
F40.1 Social phobias
0.638 0.362 0.000
Q61.9 Cystic kidney disease, unspecified
0.637 0.362 0.000
Q61.8 Other cystic kidney diseases
0.637 0.362 0.000
Q61.5 Medullary cystic kidney
0.637 0.362 0.000
Q61.4 Renal dysplasia
0.637 0.362 0.000
Q61.1 Polycystic kidney, infantile type
0.637 0.362 0.000
L75 Apocrine sweat disorders
0.637 0.363 0.000
L74 Eccrine sweat disorders
0.637 0.363 0.000
L68 Hypertrichosis
0.637 0.363 0.000
L67 Hair colour and hair shaft abnormalities
0.637 0.363 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.637 0.363 0.000
L64 Androgenic alopecia
0.637 0.363 0.000
L63 Alopecia areata
0.637 0.363 0.000
L62 Nail disorders in diseases classified elsewhere
0.637 0.363 0.000
L95.9 Vasculitis limited to skin, unspecified
0.636 0.364 0.000
E50-E64 Other nutritional deficiencies
0.636 0.364 0.000
L20-L30 Dermatitis and eczema
0.635 0.365 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.635 0.365 0.000
N75.0 Cyst of Bartholin's gland
0.634 0.366 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.633 0.366 0.000
C79.6 Secondary malignant neoplasm of ovary
0.633 0.367 0.000
S91 Open wound of ankle and foot
0.633 0.367 0.000
Y95 Nosocomial condition
0.633 0.367 0.000
F22 Persistent delusional disorders
0.632 0.368 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.631 0.369 0.000
L84 Corns and callosities
0.629 0.371 0.000
I12 Hypertensive renal disease
0.629 0.371 0.000
O20.0 Threatened abortion
0.629 0.371 0.000
S79.7 Multiple injuries of hip and thigh
0.628 0.372 0.000
D36.9 Benign neoplasm of unspecified site
0.628 0.372 0.000
D36.0 Lymph nodes
0.628 0.372 0.000
C34.8 Overlapping lesion of bronchus and lung
0.627 0.373 0.000
Y42.9 Other and unspecified hormone antagonists
0.626 0.373 0.000
Y42.4 Oral contraceptives
0.626 0.373 0.000
Y42.2 Antithyroid drugs
0.626 0.373 0.000
Y42.1 Thyroid hormones and substitutes
0.626 0.373 0.000
O97 Death from sequelae of direct obstetric causes
0.626 0.374 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.626 0.374 0.000
O95 Obstetric death of unspecified cause
0.626 0.374 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.626 0.374 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.626 0.374 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.625 0.375 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.623 0.377 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.623 0.377 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.623 0.377 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.621 0.379 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.621 0.379 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.620 0.380 0.000
T66-T78 Other and unspecified effects of external causes
0.620 0.380 0.000
O00 Ectopic pregnancy
0.620 0.380 0.000
L94.0 Localised scleroderma [morphea]
0.620 0.380 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.619 0.381 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.618 0.382 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.618 0.382 0.000
N14.4 Toxic nephropathy, not elsewhere classified
0.617 0.382 0.000
N14.3 Nephropathy induced by heavy metals
0.617 0.382 0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
0.617 0.382 0.000
N14.0 Analgesic nephropathy
0.617 0.382 0.000
C07 Malignant neoplasm of parotid gland
0.617 0.383 0.000
N20-N23 Urolithiasis
0.617 0.383 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.616 0.384 0.000
N99-N99 Other disorders of the genitourinary system
0.616 0.384 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.615 0.384 0.000
A41.8 Other specified septicaemia
0.615 0.385 0.000
F80-F89 Disorders of psychological development
0.615 0.385 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.614 0.386 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.614 0.386 0.000
C91 Lymphoid leukaemia
0.614 0.386 0.000
L60.5 Yellow nail syndrome
0.613 0.387 0.000
L60.4 Beau's lines
0.613 0.387 0.000
L60.3 Nail dystrophy
0.613 0.387 0.000
L60.1 Onycholysis
0.613 0.387 0.000
D35.0 Adrenal gland
0.613 0.387 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.613 0.387 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.612 0.388 0.000
O80-O84 Delivery
0.611 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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