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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76014476
log Bayes Factor = 18.1518
Chromosome 7   position 105,107,249  (GRCh37) Explore rs76014476 on Ensembl!
Variant rs76014476 is part of Cluster X0170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
J18 Pneumonia, organism unspecified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
N18 Chronic renal failure
0.997 0.003 0.000
N17 Acute renal failure
0.995 0.005 0.000
J18.1 Lobar pneumonia, unspecified
0.995 0.005 0.000
N17.9 Acute renal failure, unspecified
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
J18.9 Pneumonia, unspecified
0.988 0.012 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.988 0.012 0.000
J40-J47 Chronic lower respiratory diseases
0.987 0.013 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.987 0.013 0.000
Chapter IX Diseases of the circulatory system
0.986 0.014 0.000
J47 Bronchiectasis
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.979 0.021 0.000
A30-A49 Other bacterial diseases
0.977 0.023 0.000
M23 Internal derangement of knee
0.974 0.026 0.000
R50-R69 General symptoms and signs
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.967 0.033 0.000
N30-N39 Other diseases of urinary system
0.967 0.033 0.000
M25 Other joint disorders, not elsewhere classified
0.964 0.036 0.000
K70-K77 Diseases of liver
0.963 0.037 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.962 0.038 0.000
I30-I52 Other forms of heart disease
0.958 0.042 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.952 0.048 0.000
M23.3 Other meniscus derangements
0.951 0.049 0.000
N18.3 Chronic kidney disease, stage 3
0.950 0.050 0.000
R63 Symptoms and signs concerning food and fluid intake
0.945 0.055 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.944 0.056 0.000
N18.9 Chronic renal failure, unspecified
0.940 0.060 0.000
I10-I15 Hypertensive diseases
0.940 0.060 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.937 0.063 0.000
K76 Other diseases of liver
0.934 0.066 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.927 0.073 0.000
R52 Pain, not elsewhere classified
0.926 0.074 0.000
R63.0 Anorexia
0.923 0.077 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.916 0.084 0.000
M86-M90 Other osteopathies
0.914 0.086 0.000
I10 Essential (primary) hypertension
0.913 0.087 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.911 0.089 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.910 0.090 0.000
Y43 Primarily systemic agents
0.909 0.091 0.000
I51 Complications and ill-defined descriptions of heart disease
0.909 0.091 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.908 0.092 0.000
M25.5 Pain in joint
0.906 0.094 0.000
M65-M68 Disorders of synovium and tendon
0.905 0.095 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.905 0.095 0.000
J30-J39 Other diseases of upper respiratory tract
0.904 0.096 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.899 0.101 0.000
N18.4 Chronic kidney disease, stage 4
0.899 0.101 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.896 0.104 0.000
A41 Other septicaemia
0.895 0.105 0.000
Y40 Systemic antibiotics
0.895 0.105 0.000
M45-M49 Spondylopathies
0.895 0.105 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.894 0.106 0.000
D80-D89 Certain disorders involving the immune mechanism
0.893 0.107 0.000
K70 Alcoholic liver disease
0.890 0.110 0.000
A00-A09 Intestinal infectious diseases
0.887 0.113 0.000
R52.1 Chronic intractable pain
0.886 0.114 0.000
N36 Other disorders of urethra
0.885 0.115 0.000
B35-B49 Mycoses
0.884 0.116 0.000
N39 Other disorders of urinary system
0.883 0.117 0.000
R82 Other abnormal findings in urine
0.879 0.121 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.872 0.128 0.000
Chapter VI Diseases of the nervous system
0.871 0.129 0.000
D60-D64 Aplastic and other anaemias
0.870 0.130 0.000
M24 Other specific joint derangements
0.870 0.130 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.869 0.131 0.000
A40 Streptococcal septicaemia
0.869 0.131 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.865 0.135 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.861 0.139 0.000
A46 Erysipelas
0.860 0.140 0.000
R42 Dizziness and giddiness
0.860 0.140 0.000
Y43.3 Other antineoplastic drugs
0.858 0.142 0.000
M67 Other disorders of synovium and tendon
0.856 0.144 0.000
I35 Nonrheumatic aortic valve disorders
0.855 0.145 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
E10-E14 Diabetes mellitus
0.854 0.146 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.854 0.146 0.000
Y52 Agents primarily affecting the cardiovascular system
0.851 0.149 0.000
M22 Disorders of patella
0.849 0.151 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.846 0.154 0.000
M48 Other spondylopathies
0.845 0.155 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.844 0.156 0.000
M40-M43 Deforming dorsopathies
0.844 0.156 0.000
K83 Other diseases of biliary tract
0.844 0.156 0.000
A41.9 Septicaemia, unspecified
0.842 0.158 0.000
I31 Other diseases of pericardium
0.840 0.160 0.000
N39.0 Urinary tract infection, site not specified
0.839 0.161 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.839 0.161 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.838 0.162 0.000
J95-J99 Other diseases of the respiratory system
0.838 0.162 0.000
I46 Cardiac arrest
0.837 0.163 0.000
I51.7 Cardiomegaly
0.831 0.169 0.000
M70-M79 Other soft tissue disorders
0.827 0.173 0.000
K74 Fibrosis and cirrhosis of liver
0.826 0.174 0.000
M34 Systemic sclerosis
0.823 0.177 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.820 0.180 0.000
M67.8 Other specified disorders of synovium and tendon
0.818 0.182 0.000
W00-W19 Falls
0.818 0.182 0.000
Y95 Nosocomial condition
0.815 0.185 0.000
M23.1 Discoid meniscus (congenital)
0.814 0.186 0.000
N99-N99 Other disorders of the genitourinary system
0.812 0.188 0.000
Chapter XXII Codes for special purposes
0.810 0.190 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.809 0.191 0.000
K85 Acute pancreatitis
0.809 0.191 0.000
N18.8 Other chronic renal failure
0.809 0.191 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.808 0.192 0.000
I05-I09 Chronic rheumatic heart diseases
0.807 0.193 0.000
R57 Shock, not elsewhere classified
0.804 0.196 0.000
M48.0 Spinal stenosis
0.803 0.197 0.000
J00-J06 Acute upper respiratory infections
0.802 0.198 0.000
K70.3 Alcoholic cirrhosis of liver
0.802 0.198 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.802 0.198 0.000
K65-K67 Diseases of peritoneum
0.801 0.199 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.800 0.200 0.000
M25.56 Pain in joint (Lower leg)
0.800 0.200 0.000
D64 Other anaemias
0.799 0.201 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.798 0.202 0.000
I26 Pulmonary embolism
0.796 0.204 0.000
D70 Agranulocytosis
0.795 0.205 0.000
N18.5 Chronic kidney disease, stage 5
0.794 0.206 0.000
N00-N08 Glomerular diseases
0.794 0.206 0.000
K75 Other inflammatory liver diseases
0.792 0.208 0.000
R26 Abnormalities of gait and mobility
0.792 0.208 0.000
R56 Convulsions, not elsewhere classified
0.792 0.208 0.000
R50 Fever of unknown origin
0.791 0.209 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.789 0.211 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.789 0.211 0.000
D73 Diseases of spleen
0.787 0.213 0.000
K90-K93 Other diseases of the digestive system
0.787 0.213 0.000
M86 Osteomyelitis
0.784 0.216 0.000
G20-G26 Extrapyramidal and movement disorders
0.783 0.217 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.783 0.217 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.781 0.219 0.000
G40-G47 Episodic and paroxysmal disorders
0.780 0.220 0.000
A48 Other bacterial diseases, not elsewhere classified
0.779 0.221 0.000
M89 Other disorders of bone
0.779 0.221 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.777 0.223 0.000
I31.9 Disease of pericardium, unspecified
0.775 0.225 0.000
M24.1 Other articular cartilage disorders
0.773 0.227 0.000
R29.6 Tendency to fall, not elsewhere classified
0.773 0.227 0.000
K83.8 Other specified diseases of biliary tract
0.772 0.228 0.000
J11 Influenza, virus not identified
0.772 0.228 0.000
J39 Other diseases of upper respiratory tract
0.771 0.229 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.770 0.230 0.000
R53 Malaise and fatigue
0.769 0.231 0.000
N32 Other disorders of bladder
0.768 0.232 0.000
I50 Heart failure
0.768 0.232 0.000
Y40.9 Systemic antibiotic, unspecified
0.766 0.234 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.765 0.235 0.000
R59 Enlarged lymph nodes
0.765 0.235 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.764 0.235 0.000
M23.4 Loose body in knee
0.764 0.235 0.000
A04 Other bacterial intestinal infections
0.764 0.236 0.000
N36.8 Other specified disorders of urethra
0.764 0.236 0.000
J18.0 Bronchopneumonia, unspecified
0.763 0.237 0.000
E11 Non-insulin-dependent diabetes mellitus
0.763 0.237 0.000
Y40.0 Penicillins
0.760 0.240 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.757 0.242 0.000
N34 Urethritis and urethral syndrome
0.757 0.243 0.000
M80-M85 Disorders of bone density and structure
0.757 0.243 0.000
J90-J94 Other diseases of pleura
0.756 0.244 0.000
M25.0 Haemarthrosis
0.755 0.245 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.754 0.246 0.000
M48.06 Spinal stenosis (Lumbar region)
0.752 0.248 0.000
A80-A89 Viral infections of the central nervous system
0.750 0.250 0.000
R82.9 Other and unspecified abnormal finding in urine
0.750 0.250 0.000
A40.9 Streptococcal septicaemia, unspecified
0.749 0.250 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.749 0.251 0.000
I51.8 Other ill-defined heart diseases
0.749 0.251 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.748 0.252 0.000
D64.9 Anaemia, unspecified
0.748 0.252 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.747 0.253 0.000
J14 Pneumonia due to Haemophilus influenzae
0.745 0.254 0.000
M25.52 Pain in joint (Upper arm)
0.745 0.255 0.000
E10 Insulin-dependent diabetes mellitus
0.745 0.255 0.000
M22.2 Patellofemoral disorders
0.745 0.255 0.000
J35 Chronic diseases of tonsils and adenoids
0.743 0.257 0.000
J31.0 Chronic rhinitis
0.742 0.258 0.000
R68 Other general symptoms and signs
0.742 0.258 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.742 0.258 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.741 0.259 0.000
K76.7 Hepatorenal syndrome
0.741 0.259 0.000
M25.9 Joint disorder, unspecified
0.740 0.260 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.739 0.261 0.000
D86 Sarcoidosis
0.738 0.262 0.000
N18.2 Chronic kidney disease, stage 2
0.737 0.263 0.000
N30 Cystitis
0.737 0.263 0.000
R52.0 Acute pain
0.737 0.263 0.000
I28 Other diseases of pulmonary vessels
0.736 0.264 0.000
J36 Peritonsillar abscess
0.735 0.265 0.000
M60-M63 Disorders of muscles
0.735 0.265 0.000
K74.6 Other and unspecified cirrhosis of liver
0.734 0.266 0.000
D80 Immunodeficiency with predominantly antibody defects
0.733 0.267 0.000
R54 Senility
0.733 0.267 0.000
K86 Other diseases of pancreas
0.733 0.267 0.000
J02 Acute pharyngitis
0.733 0.267 0.000
R80 Isolated proteinuria
0.732 0.268 0.000
M43 Other deforming dorsopathies
0.732 0.268 0.000
R45 Symptoms and signs involving emotional state
0.730 0.269 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.270 0.000
K70.9 Alcoholic liver disease, unspecified
0.727 0.273 0.000
N10-N16 Renal tubulo-interstitial diseases
0.727 0.273 0.000
I36 Nonrheumatic tricuspid valve disorders
0.727 0.273 0.000
J44 Other chronic obstructive pulmonary disease
0.727 0.273 0.000
R82.8 Abnormal findings on cytological and histological examination of urine
0.726 0.274 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.726 0.274 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.726 0.274 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.725 0.275 0.000
G20 Parkinson's disease
0.725 0.275 0.000
M21 Other acquired deformities of limbs
0.724 0.275 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.724 0.276 0.000
N25-N29 Other disorders of kidney and ureter
0.724 0.276 0.000
N60-N64 Disorders of breast
0.723 0.277 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.723 0.277 0.000
N39.9 Disorder of urinary system, unspecified
0.723 0.277 0.000
N36.9 Urethral disorder, unspecified
0.722 0.278 0.000
I51.9 Heart disease, unspecified
0.722 0.278 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.720 0.280 0.000
M25.54 Pain in joint (Hand)
0.720 0.280 0.000
G47 Sleep disorders
0.719 0.281 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.719 0.281 0.000
R63.1 Polydipsia
0.718 0.281 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.718 0.282 0.000
Chapter VII Diseases of the eye and adnexa
0.718 0.282 0.000
R61 Hyperhidrosis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J17 Pneumonia in diseases classified elsewhere
0.717 0.283 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.717 0.283 0.000
J12 Viral pneumonia, not elsewhere classified
0.717 0.283 0.000
J09 Influenza due to certain identified influenza virus
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
J18.8 Other pneumonia, organism unspecified
0.717 0.283 0.000
J18.2 Hypostatic pneumonia, unspecified
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
N18.1 Chronic kidney disease, stage 1
0.715 0.285 0.000
E16 Other disorders of pancreatic internal secretion
0.714 0.286 0.000
N17.8 Other acute renal failure
0.714 0.286 0.000
N17.2 Acute renal failure with medullary necrosis
0.714 0.286 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.714 0.286 0.000
N17.0 Acute renal failure with tubular necrosis
0.714 0.286 0.000
J42 Unspecified chronic bronchitis
0.713 0.287 0.000
R81 Glycosuria
0.713 0.287 0.000
B35 Dermatophytosis
0.713 0.287 0.000
B49 Unspecified mycosis
0.711 0.289 0.000
M25.8 Other specified joint disorders
0.710 0.290 0.000
I46.0 Cardiac arrest with successful resuscitation
0.710 0.290 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.710 0.290 0.000
W06 Fall involving bed
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.708 0.292 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.708 0.292 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.708 0.292 0.000
J41 Simple and mucopurulent chronic bronchitis
0.708 0.292 0.000
D55-D59 Haemolytic anaemias
0.708 0.292 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.708 0.292 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.707 0.293 0.000
I00-I02 Acute rheumatic fever
0.707 0.293 0.000
J45 Asthma
0.707 0.293 0.000
K35-K38 Diseases of appendix
0.707 0.293 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.706 0.294 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.704 0.296 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.703 0.297 0.000
A07 Other protozoal intestinal diseases
0.703 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.298 0.000
Y58 Bacterial vaccines
0.702 0.298 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.702 0.298 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.702 0.298 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.298 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.702 0.298 0.000
Y48 Anaesthetics and therapeutic gases
0.702 0.298 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
D73.0 Hyposplenism
0.702 0.298 0.000
R46 Symptoms and signs involving appearance and behaviour
0.701 0.298 0.000
I38 Endocarditis, valve unspecified
0.701 0.299 0.000
A44 Bartonellosis
0.700 0.299 0.000
A43 Nocardiosis
0.700 0.299 0.000
A42 Actinomycosis
0.700 0.299 0.000
A39 Meningococcal infection
0.700 0.299 0.000
A37 Whooping cough
0.700 0.299 0.000
A36 Diphtheria
0.700 0.299 0.000
A32 Listeriosis
0.700 0.299 0.000
A31 Infection due to other mycobacteria
0.700 0.299 0.000
A30 Leprosy [Hansen's disease]
0.700 0.299 0.000
A38 Scarlet fever
0.700 0.299 0.000
A35 Other tetanus
0.700 0.299 0.000
A34 Obstetrical tetanus
0.700 0.299 0.000
A33 Tetanus neonatorum
0.700 0.299 0.000
M25.4 Effusion of joint
0.699 0.301 0.000
M23.9 Internal derangement of knee, unspecified
0.698 0.301 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.698 0.301 0.000
M23.0 Cystic meniscus
0.698 0.301 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.698 0.302 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.698 0.302 0.000
B25-B34 Other viral diseases
0.698 0.302 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.697 0.302 0.000
R62 Lack of expected normal physiological development
0.697 0.302 0.000
R64 Cachexia
0.697 0.302 0.000
R58 Haemorrhage, not elsewhere classified
0.697 0.302 0.000
K76.6 Portal hypertension
0.697 0.303 0.000
M34.9 Systemic sclerosis, unspecified
0.697 0.303 0.000
K66 Other disorders of peritoneum
0.697 0.303 0.000
N36.2 Urethral caruncle
0.697 0.303 0.000
I44 Atrioventricular and left bundle-branch block
0.697 0.303 0.000
B44 Aspergillosis
0.696 0.304 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.305 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.693 0.306 0.000
N37 Urethral disorders in diseases classified elsewhere
0.693 0.307 0.000
N33 Bladder disorders in diseases classified elsewhere
0.693 0.307 0.000
I34 Nonrheumatic mitral valve disorders
0.693 0.307 0.000
I35.0 Aortic (valve) stenosis
0.693 0.307 0.000
M87 Osteonecrosis
0.692 0.308 0.000
Y44 Agents primarily affecting blood constituents
0.692 0.308 0.000
M25.3 Other instability of joint
0.691 0.308 0.000
M25.2 Flail joint
0.691 0.308 0.000
M25.1 Fistula of joint
0.691 0.308 0.000
K77 Liver disorders in diseases classified elsewhere
0.691 0.309 0.000
K73 Chronic hepatitis, not elsewhere classified
0.691 0.309 0.000
K71 Toxic liver disease
0.691 0.309 0.000
M86.9 Osteomyelitis, unspecified
0.691 0.309 0.000
K85.9 Acute pancreatitis, unspecified
0.690 0.310 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.689 0.311 0.000
M25.7 Osteophyte
0.689 0.311 0.000
I52 Other heart disorders in diseases classified elsewhere
0.687 0.313 0.000
I48 Atrial fibrillation and flutter
0.687 0.313 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.687 0.313 0.000
I41 Myocarditis in diseases classified elsewhere
0.687 0.313 0.000
I40 Acute myocarditis
0.687 0.313 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.687 0.313 0.000
I37 Pulmonary valve disorders
0.687 0.313 0.000
I32 Pericarditis in diseases classified elsewhere
0.687 0.313 0.000
I30 Acute pericarditis
0.687 0.313 0.000
R60 Oedema, not elsewhere classified
0.687 0.313 0.000
K83.0 Cholangitis
0.686 0.314 0.000
M35 Other systemic involvement of connective tissue
0.686 0.314 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.686 0.314 0.000
M31 Other necrotising vasculopathies
0.686 0.314 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
J02.9 Acute pharyngitis, unspecified
0.684 0.316 0.000
R57.2 Septic shock
0.683 0.317 0.000
I07 Rheumatic tricuspid valve diseases
0.683 0.317 0.000
N18.0 End-stage renal disease
0.683 0.317 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.683 0.317 0.000
M23.37 Other meniscus derangements-Capsular lig
0.682 0.318 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.682 0.318 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.682 0.318 0.000
J10 Influenza due to identified influenza virus
0.681 0.319 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.681 0.319 0.000
N32.9 Bladder disorder, unspecified
0.680 0.320 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.679 0.321 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.679 0.321 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.678 0.321 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.678 0.322 0.000
J98 Other respiratory disorders
0.678 0.322 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
I50.1 Left ventricular failure
0.678 0.322 0.000
K70.4 Alcoholic hepatic failure
0.678 0.322 0.000
M90 Osteopathies in diseases classified elsewhere
0.678 0.322 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.678 0.322 0.000
N19 Unspecified renal failure
0.678 0.322 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.677 0.323 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.677 0.323 0.000
R63.5 Abnormal weight gain
0.677 0.323 0.000
R63.3 Feeding difficulties and mismanagement
0.677 0.323 0.000
R63.2 Polyphagia
0.677 0.323 0.000
D50-D53 Nutritional anaemias
0.677 0.323 0.000
N39.8 Other specified disorders of urinary system
0.676 0.324 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.675 0.325 0.000
E20-E35 Disorders of other endocrine glands
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.674 0.326 0.000
I46.9 Cardiac arrest, unspecified
0.674 0.326 0.000
I15 Secondary hypertension
0.674 0.326 0.000
I13 Hypertensive heart and renal disease
0.674 0.326 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.672 0.328 0.000
N60 Benign mammary dysplasia
0.672 0.328 0.000
K85.1 Biliary acute pancreatitis
0.672 0.328 0.000
I35.1 Aortic (valve) insufficiency
0.671 0.329 0.000
J39.2 Other diseases of pharynx
0.671 0.329 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
K76.5 Hepatic veno-occlusive disease
0.669 0.330 0.000
K76.4 Peliosis hepatis
0.669 0.330 0.000
K76.3 Infarction of liver
0.669 0.330 0.000
K76.2 Central haemorrhagic necrosis of liver
0.669 0.330 0.000
K76.1 Chronic passive congestion of liver
0.669 0.330 0.000
I71 Aortic aneurysm and dissection
0.667 0.333 0.000
K83.9 Disease of biliary tract, unspecified
0.666 0.334 0.000
J15.1 Pneumonia due to Pseudomonas
0.666 0.334 0.000
M77 Other enthesopathies
0.666 0.334 0.000
M23.5 Chronic instability of knee
0.666 0.334 0.000
R43 Disturbances of smell and taste
0.665 0.335 0.000
Y57 Other and unspecified drugs and medicaments
0.664 0.336 0.000
I42 Cardiomyopathy
0.663 0.337 0.000
V20-V29 Motorcycle rider injured in transport accident
0.662 0.337 0.000
K81 Cholecystitis
0.662 0.338 0.000
R56.8 Other and unspecified convulsions
0.662 0.338 0.000
G30-G32 Other degenerative diseases of the nervous system
0.661 0.338 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.661 0.339 0.000
A40.8 Other streptococcal septicaemia
0.661 0.339 0.000
M22.8 Other disorders of patella
0.660 0.339 0.000
W13 Fall from, out of or through building or structure
0.660 0.340 0.000
R27 Other lack of coordination
0.660 0.340 0.000
E10.9 Without complications
0.660 0.340 0.000
Y43.4 Immunosuppressive agents
0.659 0.340 0.000
R59.0 Localised enlarged lymph nodes
0.660 0.340 0.000
E40-E46 Malnutrition
0.659 0.341 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.659 0.341 0.000
I35.9 Aortic valve disorder, unspecified
0.659 0.341 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.658 0.342 0.000
K11 Diseases of salivary glands
0.658 0.342 0.000
K70.0 Alcoholic fatty liver
0.657 0.343 0.000
D68 Other coagulation defects
0.657 0.343 0.000
R50.9 Fever, unspecified
0.656 0.344 0.000
I44.7 Left bundle-branch block, unspecified
0.655 0.345 0.000
K75.4 Autoimmune hepatitis
0.655 0.345 0.000
A04.8 Other specified bacterial intestinal infections
0.655 0.345 0.000
I11 Hypertensive heart disease
0.655 0.345 0.000
J20-J22 Other acute lower respiratory infections
0.654 0.346 0.000
E16.2 Hypoglycaemia, unspecified
0.654 0.346 0.000
M25.50 Pain in joint (Multiple sites)
0.653 0.347 0.000
R29.4 Clicking hip
0.653 0.347 0.000
R29.3 Abnormal posture
0.653 0.347 0.000
R29.2 Abnormal reflex
0.653 0.347 0.000
R29.1 Meningismus
0.653 0.347 0.000
R29.0 Tetany
0.653 0.347 0.000
Y43.9 Primarily systemic agent, unspecified
0.652 0.348 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.652 0.348 0.000
Y43.6 Enzymes, not elsewhere classified
0.652 0.348 0.000
Y43.5 Acidifying and alkalising agents
0.652 0.348 0.000
Y43.2 Antineoplastic natural products
0.652 0.348 0.000
Y43.1 Antineoplastic antimetabolites
0.652 0.348 0.000
Y43.0 Antiallergic and antiemetic drugs
0.652 0.348 0.000
J90 Pleural effusion, not elsewhere classified
0.652 0.348 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.652 0.348 0.000
I51.6 Cardiovascular disease, unspecified
0.652 0.348 0.000
I51.5 Myocardial degeneration
0.652 0.348 0.000
I51.4 Myocarditis, unspecified
0.652 0.348 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.652 0.348 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.652 0.348 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.652 0.348 0.000
I51.0 Cardiac septal defect, acquired
0.652 0.348 0.000
B37 Candidiasis
0.652 0.348 0.000
E11.4 With neurological complications
0.651 0.349 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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