TreeWAS – Variant ID: rs7601713

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N18 Chronic renal failure	0.000	0.890	0.110
N18.5 Chronic kidney disease, stage 5	0.000	0.891	0.109
N18.0 End-stage renal disease	0.000	0.893	0.107
N18.9 Chronic renal failure, unspecified	0.000	0.895	0.105
N18.8 Other chronic renal failure	0.000	0.904	0.096
N18.1 Chronic kidney disease, stage 1	0.000	0.914	0.086
N17-N19 Renal failure	0.000	0.914	0.086
N17 Acute renal failure	0.000	0.923	0.077
N19 Unspecified renal failure	0.000	0.927	0.073
N18.4 Chronic kidney disease, stage 4	0.000	0.930	0.070
N17.0 Acute renal failure with tubular necrosis	0.000	0.931	0.069
N17.9 Acute renal failure, unspecified	0.000	0.933	0.067
N18.2 Chronic kidney disease, stage 2	0.000	0.934	0.066
N17.2 Acute renal failure with medullary necrosis	0.000	0.944	0.055
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.950	0.050
N17.8 Other acute renal failure	0.000	0.951	0.049
D68 Other coagulation defects	0.031	0.969	0.000
D68.0 Von Willebrand's disease	0.028	0.971	0.000
D68.2 Hereditary deficiency of other clotting factors	0.028	0.972	0.000
D68.8 Other specified coagulation defects	0.026	0.974	0.000
D68.9 Coagulation defect, unspecified	0.026	0.974	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.026	0.974	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.025	0.975	0.000
D68.1 Hereditary factor XI deficiency	0.024	0.976	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.024	0.976	0.000
D68.4 Acquired coagulation factor deficiency	0.024	0.976	0.000
D68.6 Other Thrombophilia	0.023	0.977	0.000
D66 Hereditary factor VIII deficiency	0.023	0.977	0.000
D69 Purpura and other haemorrhagic conditions	0.022	0.978	0.000
D68.5 Primary Thrombophilia	0.021	0.979	0.000
D67 Hereditary factor IX deficiency	0.019	0.980	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.018	0.982	0.000
Z99.2 Dependence on renal dialysis	0.000	0.982	0.018
D69.9 Haemorrhagic condition, unspecified	0.017	0.983	0.000
D69.4 Other primary thrombocytopenia	0.017	0.983	0.000
D69.8 Other specified haemorrhagic conditions	0.015	0.985	0.000
D69.2 Other nonthrombocytopenic purpura	0.015	0.985	0.000
D69.1 Qualitative platelet defects	0.015	0.985	0.000
D69.0 Allergic purpura	0.014	0.986	0.000
C71.1 Frontal lobe	0.000	0.987	0.013
C71 Malignant neoplasm of brain	0.000	0.989	0.011
C71.8 Overlapping lesion of brain	0.000	0.990	0.010
D69.5 Secondary thrombocytopenia	0.010	0.990	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.009	0.991	0.000
C71.4 Occipital lobe	0.000	0.991	0.009
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
Y42.5 Other oestrogens and progestogens	0.009	0.991	0.000
C71.3 Parietal lobe	0.000	0.991	0.008
Y42.0 Glucocorticoids and synthetic analogs	0.008	0.992	0.000
Y42.1 Thyroid hormones and substitutes	0.008	0.992	0.000
Y42.7 Androgens and anabolic congeners	0.008	0.992	0.000
C71.9 Brain, unspecified	0.000	0.992	0.008
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.993	0.007
C71.6 Cerebellum	0.000	0.993	0.007
C71.5 Cerebral ventricle	0.000	0.993	0.007
C71.0 Cerebrum, except lobes and ventricles	0.000	0.993	0.007
Y42.2 Antithyroid drugs	0.007	0.993	0.000
C71.7 Brain stem	0.000	0.993	0.007
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.007	0.993	0.000
Y42.4 Oral contraceptives	0.007	0.993	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.993	0.007
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.993	0.007
Y42.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.993	0.007
C71.2 Temporal lobe	0.000	0.993	0.006
C69 Malignant neoplasm of eye and adnexa	0.000	0.994	0.006
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
C69.3 Choroid	0.000	0.994	0.006
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.994	0.006
C70 Malignant neoplasm of meninges	0.000	0.994	0.006
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.994	0.006
N18.3 Chronic kidney disease, stage 3	0.000	0.994	0.006
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.994	0.006
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.994	0.005
S02.50 Fracture of tooth (closed)	0.000	0.995	0.005
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.995	0.005
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.995	0.005
C69.4 Ciliary body	0.000	0.995	0.005
S02.30 Fracture of orbital floor (closed)	0.000	0.995	0.005
C70.0 Cerebral meninges	0.000	0.995	0.005
C69.8 Overlapping lesion of eye and adnexa	0.000	0.995	0.004
C69.5 Lachrymal gland and duct	0.000	0.995	0.004
C69.1 Cornea	0.000	0.995	0.004
C69.2 Retina	0.000	0.995	0.004
E10.5 With peripheral circulatory complications	0.000	0.995	0.005
T82.1 Mechanical complication of cardiac electronic device	0.000	0.995	0.005
C72.0 Spinal cord	0.000	0.995	0.004
C70.9 Meninges, unspecified	0.000	0.996	0.004
C70.1 Spinal meninges	0.000	0.996	0.004
C69.0 Conjunctiva	0.000	0.996	0.004
C72.9 Central nervous system, unspecified	0.000	0.996	0.004
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.996	0.004
C72.5 Other and unspecified cranial nerves	0.000	0.996	0.004
C72.4 Acoustic nerve	0.000	0.996	0.004
C72.3 Optic nerve	0.000	0.996	0.004
C72.2 Olfactory nerve	0.000	0.996	0.004
C72.1 Cauda equina	0.000	0.996	0.004
Q61.5 Medullary cystic kidney	0.000	0.996	0.004
M79.66 Pain in limb (Lower leg)	0.004	0.996	0.000
R41.3 Other amnesia	0.000	0.996	0.004
C69.9 Eye, unspecified	0.000	0.996	0.004
C69.6 Orbit	0.000	0.996	0.004
Q61 Cystic kidney disease	0.000	0.996	0.004
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.996	0.004
M25.78 Osteophyte (Other)	0.000	0.996	0.004
D80.1 Nonfamilial hypogammaglobulinaemia	0.004	0.996	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.996	0.004
E10.1 With ketoacidosis	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.000	0.996	0.004
Q61.2 Polycystic kidney, adult type	0.000	0.996	0.004
S02.5 Fracture of tooth	0.000	0.996	0.004
Q61.3 Polycystic kidney, unspecified	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.004	0.996	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.996	0.004
M25.84 Other specified joint disorders (Hand)	0.000	0.996	0.004
S02.3 Fracture of orbital floor	0.000	0.996	0.004
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
Q61.4 Renal dysplasia	0.000	0.997	0.003
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
E10.2 With renal complications	0.000	0.997	0.003
M25.8 Other specified joint disorders	0.000	0.997	0.003
M19.0 Primary arthrosis of other joints	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.000	0.997	0.003
Q61.1 Polycystic kidney, infantile type	0.000	0.997	0.003
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.997	0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.000	0.997	0.003
E10.7 With multiple complications	0.000	0.997	0.003
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.997	0.003
C41.1 Mandible	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.000	0.997	0.003
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.997	0.003
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.997	0.003
M25.83 Other specified joint disorders (Forearm)	0.000	0.997	0.003
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.997	0.003
E10.6 With other specified complications	0.000	0.997	0.003
M19.08 Primary arthrosis of other joints (Other)	0.000	0.997	0.003
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.997	0.003
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.997	0.003
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.997	0.003
E10.4 With neurological complications	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.997	0.002
M25.88 Other specified joint disorders (Other)	0.000	0.997	0.003
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.997	0.003
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
M25.82 Other specified joint disorders (Upper arm)	0.000	0.997	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.997	0.003
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.997	0.002
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.998	0.002
E10.8 With unspecified complications	0.000	0.998	0.002
S42.00 Fracture of clavicle (closed)	0.002	0.998	0.000
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.998	0.002
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
E10.0 With coma	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
N86 Erosion and ectropion of cervix uteri	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.998	0.002
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
M25.4 Effusion of joint	0.002	0.998	0.000
Y84.1 Kidney dialysis	0.000	0.998	0.002
Z33 Pregnant state, incidental	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.000	0.998	0.002
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
O00.1 Tubal pregnancy	0.002	0.998	0.000
X58.9 Unspecified place	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
S02.6 Fracture of mandible	0.000	0.998	0.002
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
K81.9 Cholecystitis, unspecified	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
C50.5 Lower-outer quadrant of breast	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.998	0.002
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.002	0.998	0.000
D27 Benign neoplasm of ovary	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.998	0.002
I84.8 Unspecified haemorrhoids with other complications	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.002	0.998	0.000
T86.1 Kidney transplant failure and rejection	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.998	0.002
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
Z99.0 Dependence on aspirator	0.000	0.998	0.002
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.000	0.998	0.002
D82.1 Di George's syndrome	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
Z36.8 Other antenatal screening	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.001	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.001
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
S02.60 Fracture of mandible (closed)	0.000	0.998	0.001
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.998	0.001
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.998	0.001
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.998	0.001
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.998	0.001
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.998	0.001
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.998	0.001
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.998	0.001
S51.7 Multiple open wounds of forearm	0.000	0.998	0.002
Z99.4 Dependence on artificial heart	0.000	0.998	0.001
E10.9 Without complications	0.000	0.998	0.002
G00 Bacterial meningitis, not elsewhere classified	0.000	0.998	0.001
M84.09 Malunion of fracture (Site unspecified)	0.001	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.001
H93.1 Tinnitus	0.000	0.998	0.002
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.999	0.001
O00.9 Ectopic pregnancy, unspecified	0.001	0.999	0.000
M24.02 Loose body in joint (Upper arm)	0.001	0.999	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.999	0.001
K29.3 Chronic superficial gastritis	0.000	0.999	0.001
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.999	0.001
C92.0 Acute myeloid leukaemia	0.001	0.999	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.999	0.001
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.000	0.999	0.001
T86.0 Bone-marrow transplant rejection	0.000	0.999	0.001
M84.08 Malunion of fracture (Other)	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.999	0.001
A41.1 Septicaemia due to other specified staphylococcus	0.001	0.999	0.000
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
G00.8 Other bacterial meningitis	0.000	0.999	0.001
G00.0 Haemophilus meningitis	0.000	0.999	0.001
G30 Alzheimer's disease	0.001	0.999	0.000
S82.30 Fracture of lower end of tibia (closed)	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.999	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.999	0.001
O00 Ectopic pregnancy	0.001	0.999	0.000
G00.2 Streptococcal meningitis	0.000	0.999	0.001
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.999	0.001
S02.11 Fracture of base of skull (open)	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
D84 Other immunodeficiencies	0.001	0.999	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.999	0.001
M84.06 Malunion of fracture (Lower leg)	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
C41.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
C41.8 Overlapping lesion of bone and articular cartilage	0.000	0.999	0.001
C41.3 Ribs, sternum and clavicle	0.000	0.999	0.001
G11.4 Hereditary spastic paraplegia	0.000	0.999	0.001
T94.1 Sequelae of injuries, not specified by body region	0.000	0.999	0.001
X58 Exposure to other specified factors	0.001	0.999	0.000
G00.3 Staphylococcal meningitis	0.000	0.999	0.001
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
S42.0 Fracture of clavicle	0.001	0.999	0.000
X58.2 School, other institution and public administrative area	0.001	0.999	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.999	0.001
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.999	0.001
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.999	0.001
B25.8 Other cytomegaloviral diseases	0.000	0.999	0.001
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
C41.2 Vertebral column	0.000	0.999	0.001
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.999	0.001
K65.9 Peritonitis, unspecified	0.000	0.999	0.001
O64.1 Obstructed labour due to breech presentation	0.001	0.999	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.999	0.001
T86 Failure and rejection of transplanted organs and tissues	0.000	0.999	0.001
C41.4 Pelvic bones, sacrum and coccyx	0.000	0.999	0.001
N95.2 Postmenopausal atrophic vaginitis	0.000	0.999	0.001
O00.8 Other ectopic pregnancy	0.001	0.999	0.000
O00.2 Ovarian pregnancy	0.001	0.999	0.000
O00.0 Abdominal pregnancy	0.001	0.999	0.000
B25 Cytomegaloviral disease	0.000	0.999	0.001
M19.27 Other secondary arthrosis (Ankle and foot)	0.000	0.999	0.001
A49.8 Other bacterial infections of unspecified site	0.001	0.999	0.000
C41.0 Bones of skull and face	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.001	0.999	0.000
K07.3 Anomalies of tooth position	0.000	0.999	0.001
N13.4 Hydroureter	0.000	0.999	0.001
S42.01 Fracture of clavicle (open)	0.001	0.999	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.999	0.001
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.999	0.001
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
J94.8 Other specified pleural conditions	0.000	0.999	0.001
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.999	0.001
X58.8 Other specified place	0.001	0.999	0.000
X58.0 Home	0.001	0.999	0.000
X58.7 Farm	0.001	0.999	0.000
X58.6 Industrial and construction area	0.001	0.999	0.000
X58.5 Trade and service area	0.001	0.999	0.000
X58.4 Street and highway	0.001	0.999	0.000
X58.1 Residential institution	0.001	0.999	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.001	0.999	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.999	0.001
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
X58.3 Sports and athletics area	0.001	0.999	0.000
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
T86.3 Heart-lung transplant failure and rejection	0.000	0.999	0.001
T86.2 Heart transplant failure and rejection	0.000	0.999	0.001
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.999	0.001
M06.34 Rheumatoid nodule (Hand)	0.001	0.999	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.001	0.999	0.000
A41.8 Other specified septicaemia	0.001	0.999	0.000
B25.2 Cytomegaloviral pancreatitis	0.000	0.999	0.001
B25.1 Cytomegaloviral hepatitis	0.000	0.999	0.001
B25.0 Cytomegaloviral pneumonitis	0.000	0.999	0.001
G12.2 Motor neuron disease	0.000	0.999	0.001
K07.0 Major anomalies of jaw size	0.000	0.999	0.001
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.999	0.001
N95.1 Menopausal and female climacteric states	0.000	0.999	0.001
T21.0 Burn of unspecified degree of trunk	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.000	0.999	0.001
C22.9 Liver, unspecified	0.001	0.999	0.000
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.999	0.001
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.999	0.001
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.999	0.001
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
X58.01 Exposure to other specified factors: Home: While engaged in leisure activity	0.001	0.999	0.000
X58.89 Exposure to other specified factors: Other specified places: During unspecified activity	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
T86.4 Liver transplant failure and rejection	0.000	0.999	0.001
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.999	0.001
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.999	0.001
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.999	0.001
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.999	0.001
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.999	0.001
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.999	0.001
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.999	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.999	0.001
H05.9 Disorder of orbit, unspecified	0.000	0.999	0.001
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.999	0.001
G30.8 Other Alzheimer's disease	0.001	0.999	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.999	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.001	0.999	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.999	0.001
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.999	0.001
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.999	0.001
M79.79 Fibromyalgia (Site unspecified)	0.000	0.999	0.001
D14.3 Bronchus and lung	0.000	0.999	0.001
D48.0 Bone and articular cartilage	0.001	0.999	0.000
H05.4 Enophthalmos	0.000	0.999	0.001
M70.6 Trochanteric bursitis	0.000	0.999	0.001
N95.9 Menopausal and perimenopausal disorder, unspecified	0.000	0.999	0.001
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M70.68 Trochanteric bursitis-Other	0.000	0.999	0.001
M70.67 Trochanteric bursitis-Ankle/Foot	0.000	0.999	0.001
M70.66 Trochanteric bursitis-Lower Leg	0.000	0.999	0.001
M70.64 Trochanteric bursitis-Hand	0.000	0.999	0.001
M70.63 Trochanteric bursitis-Forearm	0.000	0.999	0.001
M70.62 Trochanteric bursitis-Upper arm	0.000	0.999	0.001
M70.61 Trochanteric bursitis-Shldr region	0.000	0.999	0.001
M70.60 Trochanteric bursitis-Mult sites	0.000	0.999	0.001
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
I72.4 Aneurysm of artery of lower extremity	0.001	0.999	0.000
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
M54.14 Radiculopathy (Thoracic region)	0.001	0.999	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.999	0.001
K86.3 Pseudocyst of pancreas	0.001	0.999	0.000
O20.0 Threatened abortion	0.000	0.999	0.001
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
X41.9 Unspecified place	0.000	0.999	0.001
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.999	0.001
M54.12 Radiculopathy (Cervical region)	0.001	0.999	0.000
C85.0 Lymphosarcoma	0.000	0.999	0.001
D57.3 Sickle-cell trait	0.001	0.999	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
G02.1 Meningitis in mycoses	0.000	0.999	0.001
H65.3 Chronic mucoid otitis media	0.000	0.999	0.001
T11.0 Superficial injury of upper limb, level unspecified	0.001	0.999	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.999	0.001
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.999	0.001
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.999	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.999	0.001
M70.69 Trochanteric bursitis-Site unspec	0.000	0.999	0.001
S36.00 Injury of spleen (without open wound into cavity)	0.000	0.999	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D57.8 Other sickle-cell disorders	0.001	0.999	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.999	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.999	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.999	0.000
E23.2 Diabetes insipidus	0.000	0.999	0.001
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.999	0.001
H00.1 Chalazion	0.000	0.999	0.001
N95.3 States associated with artificial menopause	0.000	0.999	0.001
Q66.6 Other congenital valgus deformities of feet	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
D57 Sickle-cell disorders	0.001	0.999	0.000
D55 Anaemia due to enzyme disorders	0.001	0.999	0.000
D55-D59 Haemolytic anaemias	0.001	0.999	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.999	0.000
M87.86 Other osteonecrosis (Lower leg)	0.001	0.999	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.000	0.999	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.999	0.001
G11.9 Hereditary ataxia, unspecified	0.000	0.999	0.001
G11.8 Other hereditary ataxias	0.000	0.999	0.001
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.999	0.001
G11.2 Late-onset cerebellar ataxia	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations