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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76150537
log Bayes Factor = 15.7037
Chromosome 2   position 67,063,487  (GRCh37) Explore rs76150537 on Ensembl!
Variant rs76150537 is part of Cluster X0155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I20 Angina pectoris
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
I20.0 Unstable angina
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
M20-M25 Other joint disorders
0.986 0.014 0.000
I25 Chronic ischaemic heart disease
0.985 0.015 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.979 0.021 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.979 0.021 0.000
I21 Acute myocardial infarction
0.978 0.022 0.000
E70-E90 Metabolic disorders
0.978 0.022 0.000
Chapter X Diseases of the respiratory system
0.974 0.026 0.000
Chapter VII Diseases of the eye and adnexa
0.973 0.027 0.000
I84 Haemorrhoids
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.971 0.029 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.969 0.031 0.000
E78.0 Pure hypercholesterolaemia
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.965 0.035 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.963 0.037 0.000
M54 Dorsalgia
0.960 0.040 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
I84.6 Residual haemorrhoidal skin tags
0.957 0.043 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.955 0.045 0.000
Chapter XXI Factors influencing health status and contact with health services
0.955 0.045 0.000
M54.5 Low back pain
0.953 0.047 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.952 0.048 0.000
J40-J47 Chronic lower respiratory diseases
0.951 0.049 0.000
M23 Internal derangement of knee
0.948 0.052 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.946 0.054 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.941 0.059 0.000
H30-H36 Disorders of choroid and retina
0.940 0.060 0.000
M15-M19 Arthrosis
0.938 0.062 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.934 0.066 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.931 0.069 0.000
I25.1 Atherosclerotic heart disease
0.926 0.074 0.000
I20.9 Angina pectoris, unspecified
0.924 0.076 0.000
M45-M49 Spondylopathies
0.923 0.077 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.921 0.079 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.920 0.080 0.000
I35 Nonrheumatic aortic valve disorders
0.918 0.082 0.000
M54.56 Low back pain (Lumbar region)
0.910 0.090 0.000
E20-E35 Disorders of other endocrine glands
0.908 0.092 0.000
M25 Other joint disorders, not elsewhere classified
0.906 0.094 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.904 0.096 0.000
Chapter V Mental and behavioural disorders
0.900 0.100 0.000
R50-R69 General symptoms and signs
0.899 0.101 0.000
H35 Other retinal disorders
0.897 0.103 0.000
I95 Hypotension
0.896 0.104 0.000
R07 Pain in throat and chest
0.894 0.106 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.894 0.106 0.000
M54.57 Low back pain (Lumbosacral region)
0.892 0.108 0.000
I44 Atrioventricular and left bundle-branch block
0.891 0.109 0.000
M13 Other arthritis
0.890 0.110 0.000
M16 Coxarthrosis [arthrosis of hip]
0.887 0.113 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.885 0.115 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.879 0.121 0.000
I84.1 Internal haemorrhoids with other complications
0.877 0.123 0.000
I05-I09 Chronic rheumatic heart diseases
0.876 0.124 0.000
Chapter VI Diseases of the nervous system
0.870 0.130 0.000
M80-M85 Disorders of bone density and structure
0.869 0.131 0.000
I95.9 Hypotension, unspecified
0.865 0.135 0.000
I44.0 Atrioventricular block, first degree
0.864 0.136 0.000
M16.0 Primary coxarthrosis, bilateral
0.864 0.136 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.862 0.138 0.000
H34 Retinal vascular occlusions
0.852 0.148 0.000
M65-M68 Disorders of synovium and tendon
0.851 0.148 0.000
J44 Other chronic obstructive pulmonary disease
0.851 0.149 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.850 0.150 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.850 0.150 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.848 0.152 0.000
M17 Gonarthrosis [arthrosis of knee]
0.848 0.152 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.843 0.157 0.000
M13.9 Arthritis, unspecified
0.839 0.161 0.000
I45 Other conduction disorders
0.839 0.161 0.000
Chapter XX External causes of morbidity and mortality
0.838 0.162 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.835 0.165 0.000
J20-J22 Other acute lower respiratory infections
0.834 0.166 0.000
S40-S49 Injuries to the shoulder and upper arm
0.831 0.169 0.000
J47 Bronchiectasis
0.831 0.169 0.000
R07.3 Other chest pain
0.831 0.169 0.000
I21.9 Acute myocardial infarction, unspecified
0.829 0.171 0.000
M31 Other necrotising vasculopathies
0.827 0.173 0.000
M47 Spondylosis
0.826 0.174 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.824 0.176 0.000
J40 Bronchitis, not specified as acute or chronic
0.820 0.180 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.819 0.181 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.817 0.183 0.000
M06 Other rheumatoid arthritis
0.817 0.183 0.000
M22 Disorders of patella
0.815 0.185 0.000
S60-S69 Injuries to the wrist and hand
0.814 0.186 0.000
I35.1 Aortic (valve) insufficiency
0.812 0.188 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.812 0.188 0.000
I35.0 Aortic (valve) stenosis
0.812 0.188 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.810 0.190 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.810 0.190 0.000
J45 Asthma
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.810 0.190 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.809 0.191 0.000
J95-J99 Other diseases of the respiratory system
0.805 0.195 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.804 0.196 0.000
M46 Other inflammatory spondylopathies
0.801 0.199 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.799 0.200 0.000
H35.8 Other specified retinal disorders
0.799 0.201 0.000
I47 Paroxysmal tachycardia
0.799 0.201 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.798 0.202 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.796 0.203 0.000
R01 Cardiac murmurs and other cardiac sounds
0.796 0.204 0.000
I20.1 Angina pectoris with documented spasm
0.796 0.204 0.000
I84.2 Internal haemorrhoids without complication
0.794 0.206 0.000
M54.2 Cervicalgia
0.792 0.207 0.000
H35.3 Degeneration of macula and posterior pole
0.792 0.208 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.791 0.209 0.000
M25.8 Other specified joint disorders
0.791 0.209 0.000
M21 Other acquired deformities of limbs
0.789 0.211 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.788 0.212 0.000
M54.55 Low back pain (Thoracolumbar region)
0.787 0.213 0.000
H43-H45 Disorders of vitreous body and globe
0.786 0.214 0.000
M23.5 Chronic instability of knee
0.784 0.216 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.784 0.216 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.783 0.217 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.782 0.218 0.000
M17.0 Primary gonarthrosis, bilateral
0.781 0.219 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.781 0.219 0.000
M91-M94 Chondropathies
0.780 0.220 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.780 0.220 0.000
M40-M43 Deforming dorsopathies
0.779 0.221 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.777 0.223 0.000
R07.4 Chest pain, unspecified
0.777 0.223 0.000
I80 Phlebitis and thrombophlebitis
0.777 0.223 0.000
M25.4 Effusion of joint
0.776 0.224 0.000
I34 Nonrheumatic mitral valve disorders
0.775 0.225 0.000
R61 Hyperhidrosis
0.774 0.226 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.774 0.226 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
M17.1 Other primary gonarthrosis
0.773 0.227 0.000
I08 Multiple valve diseases
0.773 0.227 0.000
I35.9 Aortic valve disorder, unspecified
0.772 0.228 0.000
I21.4 Acute subendocardial myocardial infarction
0.770 0.230 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.770 0.230 0.000
J60-J70 Lung diseases due to external agents
0.769 0.231 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.768 0.232 0.000
H31 Other disorders of choroid
0.767 0.232 0.000
I25.5 Ischaemic cardiomyopathy
0.766 0.234 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.766 0.234 0.000
L85 Other epidermal thickening
0.764 0.236 0.000
M47.8 Other spondylosis
0.762 0.238 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.239 0.000
M54.1 Radiculopathy
0.759 0.241 0.000
E50-E64 Other nutritional deficiencies
0.759 0.241 0.000
M70-M79 Other soft tissue disorders
0.758 0.242 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.757 0.243 0.000
H34.8 Other retinal vascular occlusions
0.757 0.243 0.000
M10 Gout
0.753 0.247 0.000
Z50 Care involving use of rehabilitation procedures
0.753 0.247 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.752 0.248 0.000
T86 Failure and rejection of transplanted organs and tissues
0.751 0.249 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
J46 Status asthmaticus
0.749 0.251 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.748 0.252 0.000
F30-F39 Mood [affective] disorders
0.747 0.253 0.000
E83 Disorders of mineral metabolism
0.747 0.253 0.000
E27 Other disorders of adrenal gland
0.746 0.253 0.000
R63 Symptoms and signs concerning food and fluid intake
0.746 0.254 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.745 0.255 0.000
M86-M90 Other osteopathies
0.744 0.255 0.000
Chapter I Certain infectious and parasitic diseases
0.744 0.256 0.000
R60 Oedema, not elsewhere classified
0.744 0.256 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.744 0.256 0.000
M65 Synovitis and tenosynovitis
0.744 0.256 0.000
Z36 Antenatal screening
0.742 0.258 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.739 0.261 0.000
R53 Malaise and fatigue
0.739 0.261 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.738 0.262 0.000
L81 Other disorders of pigmentation
0.738 0.262 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.738 0.262 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.737 0.263 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.736 0.264 0.000
R02 Gangrene, not elsewhere classified
0.736 0.264 0.000
R73 Elevated blood glucose level
0.736 0.264 0.000
Z72 Problems related to lifestyle
0.736 0.264 0.000
J22 Unspecified acute lower respiratory infection
0.733 0.267 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.733 0.267 0.000
M24 Other specific joint derangements
0.731 0.269 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
J00-J06 Acute upper respiratory infections
0.728 0.272 0.000
E22 Hyperfunction of pituitary gland
0.727 0.273 0.000
I22 Subsequent myocardial infarction
0.726 0.273 0.000
I81 Portal vein thrombosis
0.725 0.275 0.000
E26 Hyperaldosteronism
0.724 0.276 0.000
G20-G26 Extrapyramidal and movement disorders
0.724 0.276 0.000
L40-L45 Papulosquamous disorders
0.724 0.276 0.000
G70-G73 Diseases of myoneural junction and muscle
0.723 0.276 0.000
H10-H13 Disorders of conjunctiva
0.723 0.276 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.722 0.278 0.000
M81 Osteoporosis without pathological fracture
0.721 0.279 0.000
S20-S29 Injuries to the thorax
0.719 0.280 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.718 0.282 0.000
M54.4 Lumbago with sciatica
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F03 Unspecified dementia
0.716 0.284 0.000
T81 Complications of procedures, not elsewhere classified
0.715 0.285 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.713 0.287 0.000
I84.3 External thrombosed haemorrhoids
0.713 0.287 0.000
J30-J39 Other diseases of upper respiratory tract
0.713 0.287 0.000
H55-H59 Other disorders of eye and adnexa
0.712 0.288 0.000
R55 Syncope and collapse
0.712 0.288 0.000
I30 Acute pericarditis
0.711 0.288 0.000
I84.5 External haemorrhoids without complication
0.711 0.289 0.000
L83 Acanthosis nigricans
0.709 0.291 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.708 0.292 0.000
T87 Complications peculiar to reattachment and amputation
0.708 0.292 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.708 0.292 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M34 Systemic sclerosis
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
I25.6 Silent myocardial ischaemia
0.706 0.293 0.000
I25.4 Coronary artery aneurysm
0.706 0.293 0.000
I25.3 Aneurysm of heart
0.706 0.293 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.706 0.293 0.000
M06.9 Rheumatoid arthritis, unspecified
0.706 0.294 0.000
M25.5 Pain in joint
0.705 0.295 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.703 0.297 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.702 0.298 0.000
L85.9 Epidermal thickening, unspecified
0.702 0.298 0.000
I88 Nonspecific lymphadenitis
0.702 0.298 0.000
I87 Other disorders of veins
0.702 0.298 0.000
I82 Other venous embolism and thrombosis
0.702 0.298 0.000
Z75 Problems related to medical facilities and other health care
0.702 0.298 0.000
I24 Other acute ischaemic heart diseases
0.702 0.298 0.000
M23.8 Other internal derangements of knee
0.702 0.298 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.701 0.298 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.701 0.298 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.701 0.298 0.000
E88 Other metabolic disorders
0.701 0.299 0.000
E85 Amyloidosis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
M25.84 Other specified joint disorders (Hand)
0.701 0.299 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.701 0.299 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.700 0.300 0.000
I60-I69 Cerebrovascular diseases
0.699 0.301 0.000
Z95.2 Presence of prosthetic heart valve
0.699 0.301 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.698 0.302 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.698 0.302 0.000
H35.0 Background retinopathy and retinal vascular changes
0.697 0.303 0.000
L60-L75 Disorders of skin appendages
0.697 0.303 0.000
I84.0 Internal thrombosed haemorrhoids
0.696 0.304 0.000
E23 Hypofunction and other disorders of pituitary gland
0.696 0.304 0.000
M53 Other dorsopathies, not elsewhere classified
0.696 0.304 0.000
R20 Disturbances of skin sensation
0.695 0.305 0.000
E78.8 Other disorders of lipoprotein metabolism
0.695 0.305 0.000
E78.6 Lipoprotein deficiency
0.695 0.305 0.000
E78.4 Other hyperlipidaemia
0.695 0.305 0.000
E78.3 Hyperchylomicronaemia
0.695 0.305 0.000
E78.2 Mixed hyperlipidaemia
0.695 0.305 0.000
E78.1 Pure hyperglyceridaemia
0.695 0.305 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.694 0.306 0.000
H53-H54 Visual disturbances and blindness
0.694 0.306 0.000
M31.6 Other giant cell arteritis
0.693 0.307 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.693 0.307 0.000
H34.2 Other retinal artery occlusions
0.692 0.308 0.000
I52 Other heart disorders in diseases classified elsewhere
0.692 0.308 0.000
I48 Atrial fibrillation and flutter
0.692 0.308 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.692 0.308 0.000
I41 Myocarditis in diseases classified elsewhere
0.692 0.308 0.000
I40 Acute myocarditis
0.692 0.308 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.692 0.308 0.000
I37 Pulmonary valve disorders
0.692 0.308 0.000
I36 Nonrheumatic tricuspid valve disorders
0.692 0.308 0.000
I32 Pericarditis in diseases classified elsewhere
0.692 0.308 0.000
L89 Decubitus ulcer
0.692 0.308 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.691 0.309 0.000
Chapter VIII Diseases of the ear and mastoid process
0.691 0.309 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.690 0.309 0.000
E89.3 Postprocedural hypopituitarism
0.690 0.310 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.690 0.310 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.690 0.310 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.690 0.310 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.690 0.310 0.000
Z74 Problems related to care-provider dependency
0.689 0.311 0.000
M54.8 Other dorsalgia
0.688 0.311 0.000
M54.6 Pain in thoracic spine
0.688 0.311 0.000
M54.0 Panniculitis affecting regions of neck and back
0.688 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.688 0.312 0.000
M12 Other specific arthropathies
0.688 0.312 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.688 0.312 0.000
M08 Juvenile arthritis
0.688 0.312 0.000
M07 Psoriatic and enteropathic arthropathies
0.688 0.312 0.000
M05 Seropositive rheumatoid arthritis
0.688 0.312 0.000
R54 Senility
0.688 0.312 0.000
I08.0 Disorders of both mitral and aortic valves
0.688 0.312 0.000
M84 Disorders of continuity of bone
0.688 0.312 0.000
M22.8 Other disorders of patella
0.688 0.312 0.000
R68 Other general symptoms and signs
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
I47.1 Supraventricular tachycardia
0.686 0.314 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.685 0.314 0.000
R61.9 Hyperhidrosis, unspecified
0.685 0.315 0.000
J98 Other respiratory disorders
0.684 0.316 0.000
M54.54 Low back pain-Thoracic
0.684 0.316 0.000
M54.53 Low back pain-Cervicothoracic
0.684 0.316 0.000
M54.52 Low back pain-Cervical
0.684 0.316 0.000
M54.51 Low back pain-Occipit-atl-axl
0.684 0.316 0.000
M54.50 Low back pain (Multiple sites in spine)
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.683 0.317 0.000
M25.46 Effusion of joint (Lower leg)
0.683 0.317 0.000
R01.1 Cardiac murmur, unspecified
0.683 0.317 0.000
L10-L14 Bullous disorders
0.683 0.317 0.000
M11 Other crystal arthropathies
0.682 0.318 0.000
J41 Simple and mucopurulent chronic bronchitis
0.682 0.318 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.681 0.319 0.000
I05 Rheumatic mitral valve diseases
0.681 0.319 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.681 0.319 0.000
I86 Varicose veins of other sites
0.680 0.320 0.000
Z36.8 Other antenatal screening
0.680 0.320 0.000
S70-S79 Injuries to the hip and thigh
0.679 0.320 0.000
M23.9 Internal derangement of knee, unspecified
0.679 0.320 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.679 0.320 0.000
M23.1 Discoid meniscus (congenital)
0.679 0.320 0.000
M23.0 Cystic meniscus
0.679 0.320 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.679 0.320 0.000
G30-G32 Other degenerative diseases of the nervous system
0.679 0.321 0.000
J45.9 Asthma, unspecified
0.679 0.321 0.000
I31 Other diseases of pericardium
0.678 0.322 0.000
R63.0 Anorexia
0.677 0.323 0.000
I33 Acute and subacute endocarditis
0.676 0.323 0.000
T90 Sequelae of injuries of head
0.676 0.324 0.000
M45 Ankylosing spondylitis
0.675 0.324 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.675 0.325 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.674 0.325 0.000
I99 Other and unspecified disorders of circulatory system
0.674 0.325 0.000
L50-L54 Urticaria and erythema
0.674 0.326 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.674 0.326 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.674 0.326 0.000
H30 Chorioretinal inflammation
0.674 0.326 0.000
T66-T78 Other and unspecified effects of external causes
0.673 0.327 0.000
M15 Polyarthrosis
0.672 0.327 0.000
I49 Other cardiac arrhythmias
0.672 0.328 0.000
Z97 Presence of other devices
0.672 0.328 0.000
Z72.1 Alcohol use
0.672 0.328 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.670 0.330 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.670 0.330 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.670 0.330 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.670 0.330 0.000
T82.3 Mechanical complication of other vascular grafts
0.670 0.330 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.670 0.330 0.000
T82.1 Mechanical complication of cardiac electronic device
0.670 0.330 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.670 0.330 0.000
R59 Enlarged lymph nodes
0.669 0.331 0.000
M23.3 Other meniscus derangements
0.668 0.332 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.667 0.333 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.667 0.333 0.000
R47-R49 Symptoms and signs involving speech and voice
0.665 0.334 0.000
R07.1 Chest pain on breathing
0.665 0.335 0.000
R56 Convulsions, not elsewhere classified
0.664 0.336 0.000
I45.5 Other specified heart block
0.664 0.336 0.000
R73.9 Hyperglycaemia, unspecified
0.663 0.337 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.662 0.338 0.000
H16 Keratitis
0.662 0.338 0.000
M49 Spondylopathies in diseases classified elsewhere
0.662 0.338 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.662 0.338 0.000
S40 Superficial injury of shoulder and upper arm
0.662 0.338 0.000
I34.0 Mitral (valve) insufficiency
0.661 0.339 0.000
H04 Disorders of lachrymal system
0.661 0.339 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.661 0.339 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.661 0.339 0.000
S32 Fracture of lumbar spine and pelvis
0.660 0.340 0.000
M23.4 Loose body in knee
0.659 0.341 0.000
I45.9 Conduction disorder, unspecified
0.659 0.341 0.000
Z93 Artificial opening status
0.659 0.341 0.000
I35.8 Other aortic valve disorders
0.658 0.342 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.658 0.342 0.000
I42 Cardiomyopathy
0.658 0.342 0.000
M54.29 Cervicalgia-Site unspe
0.657 0.343 0.000
Z50.1 Other physical therapy
0.657 0.343 0.000
I45.1 Other and unspecified right bundle-branch block
0.655 0.345 0.000
F80-F89 Disorders of psychological development
0.655 0.345 0.000
I84.8 Unspecified haemorrhoids with other complications
0.655 0.345 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.654 0.346 0.000
Z50.0 Cardiac rehabilitation
0.653 0.347 0.000
E87.5 Hyperkalaemia
0.652 0.347 0.000
I84.4 External haemorrhoids with other complications
0.652 0.348 0.000
S42 Fracture of shoulder and upper arm
0.651 0.349 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.651 0.349 0.000
E34 Other endocrine disorders
0.651 0.349 0.000
E32 Diseases of thymus
0.651 0.349 0.000
E31 Polyglandular dysfunction
0.651 0.349 0.000
E30 Disorders of puberty, not elsewhere classified
0.651 0.349 0.000
E29 Testicular dysfunction
0.651 0.349 0.000
E28 Ovarian dysfunction
0.651 0.349 0.000
E25 Adrenogenital disorders
0.651 0.349 0.000
E24 Cushing's syndrome
0.651 0.349 0.000
E20 Hypoparathyroidism
0.651 0.349 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.651 0.349 0.000
H35.4 Peripheral retinal degeneration
0.651 0.349 0.000
M54.59 Low back pain (Site unspecified)
0.651 0.349 0.000
M85 Other disorders of bone density and structure
0.651 0.349 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.651 0.349 0.000
H01 Other inflammation of eyelid
0.651 0.349 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.650 0.350 0.000
M47.82 Other spondylosis (Cervical region)
0.649 0.351 0.000
M25.9 Joint disorder, unspecified
0.649 0.351 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.649 0.351 0.000
M25.3 Other instability of joint
0.649 0.351 0.000
M25.2 Flail joint
0.649 0.351 0.000
M25.1 Fistula of joint
0.649 0.351 0.000
M25.0 Haemarthrosis
0.649 0.351 0.000
W20-W49 Exposure to inanimate mechanical forces
0.649 0.351 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.649 0.351 0.000
S80-S89 Injuries to the knee and lower leg
0.648 0.351 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.648 0.352 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.648 0.352 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.648 0.352 0.000
I95.1 Orthostatic hypotension
0.647 0.353 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.646 0.354 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.645 0.354 0.000
F70-F79 Mental retardation
0.645 0.354 0.000
F60-F69 Disorders of adult personality and behaviour
0.645 0.354 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.645 0.354 0.000
Z50.2 Alcohol rehabilitation
0.645 0.355 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.645 0.355 0.000
M75 Shoulder lesions
0.645 0.355 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.644 0.355 0.000
R62 Lack of expected normal physiological development
0.644 0.355 0.000
R57 Shock, not elsewhere classified
0.644 0.355 0.000
R64 Cachexia
0.644 0.355 0.000
R58 Haemorrhage, not elsewhere classified
0.644 0.355 0.000
F33 Recurrent depressive disorder
0.644 0.356 0.000
H31.0 Chorioretinal scars
0.644 0.356 0.000
R60.0 Localised oedema
0.644 0.356 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.644 0.356 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.644 0.356 0.000
R21 Rash and other nonspecific skin eruption
0.643 0.357 0.000
H35.9 Retinal disorder, unspecified
0.643 0.357 0.000
H35.7 Separation of retinal layers
0.643 0.357 0.000
H35.6 Retinal haemorrhage
0.643 0.357 0.000
H35.5 Hereditary retinal dystrophy
0.643 0.357 0.000
H35.2 Other proliferative retinopathy
0.643 0.357 0.000
H35.1 Retinopathy of prematurity
0.643 0.357 0.000
S64 Injury of nerves at wrist and hand level
0.642 0.358 0.000
I95.8 Other hypotension
0.642 0.358 0.000
I95.0 Idiopathic hypotension
0.642 0.358 0.000
L20-L30 Dermatitis and eczema
0.642 0.358 0.000
V10-V19 Pedal cyclist injured in transport accident
0.641 0.359 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.640 0.360 0.000
H43 Disorders of vitreous body
0.640 0.360 0.000
I44.6 Other and unspecified fascicular block
0.639 0.361 0.000
I44.5 Left posterior fascicular block
0.639 0.361 0.000
I44.4 Left anterior fascicular block
0.639 0.361 0.000
I44.3 Other and unspecified atrioventricular block
0.639 0.361 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.638 0.361 0.000
E87.0 Hyperosmolality and hypernatraemia
0.638 0.362 0.000
M13.8 Other specified arthritis
0.638 0.362 0.000
M13.1 Monoarthritis, not elsewhere classified
0.638 0.362 0.000
M13.0 Polyarthritis, unspecified
0.638 0.362 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.638 0.362 0.000
S50-S59 Injuries to the elbow and forearm
0.637 0.362 0.000
F99-F99 Unspecified mental disorder
0.636 0.363 0.000
M16.7 Other secondary coxarthrosis
0.636 0.364 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.636 0.364 0.000
M16.5 Other posttraumatic coxarthrosis
0.636 0.364 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.636 0.364 0.000
M16.3 Other dysplastic coxarthrosis
0.636 0.364 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.636 0.364 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.636 0.364 0.000
L81.9 Disorder of pigmentation, unspecified
0.636 0.364 0.000
M21.2 Flexion deformity
0.636 0.364 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.635 0.365 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.635 0.365 0.000
M47.89 Other spondylosis (Site unspecified)
0.634 0.366 0.000
J45.0 Predominantly allergic asthma
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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