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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76151551
log Bayes Factor = 7.90722
Chromosome 18   position 62,136,863  (GRCh37) Explore rs76151551 on Ensembl!
Variant rs76151551 is part of Cluster X0193

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.995 0.005 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
R05 Cough
0.993 0.007 0.000
H65-H75 Diseases of middle ear and mastoid
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.988 0.012 0.000
F30-F39 Mood [affective] disorders
0.987 0.013 0.000
R06 Abnormalities of breathing
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.986 0.014 0.000
M79.6 Pain in limb
0.986 0.014 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.981 0.019 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.977 0.023 0.000
F32 Depressive episode
0.971 0.029 0.000
R20 Disturbances of skin sensation
0.969 0.031 0.000
F32.9 Depressive episode, unspecified
0.966 0.034 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.966 0.034 0.000
Chapter XX External causes of morbidity and mortality
0.965 0.035 0.000
M79.69 Pain in limb (Site unspecified)
0.964 0.036 0.000
R06.0 Dyspnoea
0.957 0.043 0.000
R26 Abnormalities of gait and mobility
0.957 0.043 0.000
M79.0 Rheumatism, unspecified
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
M20-M25 Other joint disorders
0.950 0.050 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.949 0.051 0.000
M79.8 Other specified soft tissue disorders
0.949 0.051 0.000
R47-R49 Symptoms and signs involving speech and voice
0.943 0.057 0.000
F31 Bipolar affective disorder
0.943 0.057 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.942 0.058 0.000
R20.2 Paraesthesia of skin
0.939 0.061 0.000
M25 Other joint disorders, not elsewhere classified
0.938 0.062 0.000
H65 Nonsuppurative otitis media
0.936 0.064 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.932 0.068 0.000
R06.5 Mouth breathing
0.931 0.069 0.000
S20-S29 Injuries to the thorax
0.928 0.071 0.000
R23 Other skin changes
0.915 0.085 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.911 0.089 0.000
Chapter X Diseases of the respiratory system
0.903 0.097 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.901 0.099 0.000
M80-M85 Disorders of bone density and structure
0.896 0.104 0.000
H73 Other disorders of tympanic membrane
0.894 0.106 0.000
J09-J18 Influenza and pneumonia
0.891 0.109 0.000
R06.2 Wheezing
0.891 0.109 0.000
H72 Perforation of tympanic membrane
0.891 0.109 0.000
F31.9 Bipolar affective disorder, unspecified
0.889 0.111 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.884 0.116 0.000
Q43 Other congenital malformations of intestine
0.883 0.117 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.883 0.117 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.882 0.118 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.881 0.119 0.000
M79.2 Neuralgia and neuritis, unspecified
0.880 0.120 0.000
J18 Pneumonia, organism unspecified
0.879 0.121 0.000
J20-J22 Other acute lower respiratory infections
0.875 0.125 0.000
Chapter I Certain infectious and parasitic diseases
0.868 0.132 0.000
M05-M14 Inflammatory polyarthropathies
0.866 0.134 0.000
T42.4 Benzodiazepines
0.864 0.136 0.000
T39.1 4-Aminophenol derivatives
0.863 0.137 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.862 0.138 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.860 0.140 0.000
R49 Voice disturbances
0.860 0.140 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.857 0.143 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.854 0.146 0.000
M25.5 Pain in joint
0.851 0.149 0.000
H66 Suppurative and unspecified otitis media
0.849 0.151 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.846 0.154 0.000
Y42.7 Androgens and anabolic congeners
0.846 0.154 0.000
H65.3 Chronic mucoid otitis media
0.844 0.156 0.000
Q50-Q56 Congenital malformations of genital organs
0.844 0.156 0.000
J18.0 Bronchopneumonia, unspecified
0.843 0.157 0.000
R25 Abnormal involuntary movements
0.843 0.157 0.000
S22.4 Multiple fractures of ribs
0.842 0.158 0.000
H74 Other disorders of middle ear and mastoid
0.838 0.162 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.832 0.168 0.000
T51 Toxic effect of alcohol
0.830 0.170 0.000
M65-M68 Disorders of synovium and tendon
0.828 0.172 0.000
J22 Unspecified acute lower respiratory infection
0.825 0.175 0.000
T79-T79 Certain early complications of trauma
0.824 0.176 0.000
H73.8 Other specified disorders of tympanic membrane
0.824 0.176 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.821 0.179 0.000
M25.50 Pain in joint (Multiple sites)
0.820 0.180 0.000
M25.0 Haemarthrosis
0.817 0.183 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.816 0.184 0.000
M79.1 Myalgia
0.815 0.185 0.000
M23 Internal derangement of knee
0.814 0.186 0.000
Q43.0 Meckel's diverticulum
0.813 0.187 0.000
S22.40 Multiple fractures of ribs (closed)
0.812 0.188 0.000
R47 Speech disturbances, not elsewhere classified
0.812 0.188 0.000
H60-H62 Diseases of external ear
0.809 0.191 0.000
M85 Other disorders of bone density and structure
0.808 0.192 0.000
W20-W49 Exposure to inanimate mechanical forces
0.808 0.192 0.000
M07 Psoriatic and enteropathic arthropathies
0.806 0.194 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.803 0.197 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.802 0.198 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.801 0.199 0.000
M79.62 Pain in limb (Upper arm)
0.801 0.199 0.000
R49.0 Dysphonia
0.800 0.200 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.800 0.200 0.000
M25.8 Other specified joint disorders
0.799 0.201 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.797 0.203 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.796 0.204 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.796 0.204 0.000
M45-M49 Spondylopathies
0.795 0.205 0.000
M79.64 Pain in limb (Hand)
0.795 0.205 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.793 0.207 0.000
M86-M90 Other osteopathies
0.792 0.208 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.791 0.209 0.000
J18.1 Lobar pneumonia, unspecified
0.788 0.212 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.788 0.212 0.000
Chapter XXII Codes for special purposes
0.787 0.213 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.786 0.214 0.000
M75 Shoulder lesions
0.782 0.218 0.000
F60-F69 Disorders of adult personality and behaviour
0.781 0.218 0.000
M25.9 Joint disorder, unspecified
0.781 0.219 0.000
M25.56 Pain in joint (Lower leg)
0.779 0.221 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.778 0.222 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.776 0.224 0.000
T63 Toxic effect of contact with venomous animals
0.776 0.224 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.775 0.225 0.000
T36 Poisoning by systemic antibiotics
0.775 0.225 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.773 0.227 0.000
R27 Other lack of coordination
0.772 0.228 0.000
M00-M03 Infectious arthropathies
0.769 0.231 0.000
M31 Other necrotising vasculopathies
0.768 0.232 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.766 0.234 0.000
F30 Manic episode
0.766 0.234 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.765 0.235 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.765 0.235 0.000
T39.0 Salicylates
0.764 0.236 0.000
Y57 Other and unspecified drugs and medicaments
0.764 0.236 0.000
R23.8 Other and unspecified skin changes
0.763 0.237 0.000
X60-X84 Intentional self-harm
0.763 0.237 0.000
M07.3 Other psoriatic arthropathies
0.763 0.237 0.000
T51.9 Alcohol, unspecified
0.762 0.238 0.000
M25.7 Osteophyte
0.761 0.239 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.761 0.239 0.000
M79.08 Rheumatism, unspecified (Other)
0.758 0.242 0.000
M77 Other enthesopathies
0.758 0.242 0.000
M79.9 Soft tissue disorder, unspecified
0.755 0.245 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.755 0.245 0.000
F32.0 Mild depressive episode
0.755 0.245 0.000
H66.9 Otitis media, unspecified
0.754 0.246 0.000
M91-M94 Chondropathies
0.753 0.247 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.753 0.247 0.000
W50-W64 Exposure to animate mechanical forces
0.753 0.247 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.751 0.249 0.000
T00-T07 Injuries involving multiple body regions
0.751 0.249 0.000
F40 Phobic anxiety disorders
0.749 0.251 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.748 0.252 0.000
T56 Toxic effect of metals
0.747 0.253 0.000
M76 Enthesopathies of lower limb, excluding foot
0.747 0.253 0.000
J20 Acute bronchitis
0.747 0.253 0.000
M60-M63 Disorders of muscles
0.746 0.253 0.000
M25.51 Pain in joint (Shoulder region)
0.745 0.255 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.743 0.256 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.743 0.256 0.000
M65 Synovitis and tenosynovitis
0.742 0.258 0.000
Y43 Primarily systemic agents
0.741 0.259 0.000
R47.8 Other and unspecified speech disturbances
0.741 0.259 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.741 0.259 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.740 0.260 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.738 0.262 0.000
X20-X29 Contact with venomous animals and plants
0.735 0.265 0.000
T46.1 Calcium-channel blockers
0.735 0.265 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.735 0.265 0.000
H65.4 Other chronic nonsuppurative otitis media
0.734 0.266 0.000
R04 Haemorrhage from respiratory passages
0.734 0.266 0.000
M72 Fibroblastic disorders
0.733 0.267 0.000
T66-T78 Other and unspecified effects of external causes
0.732 0.268 0.000
M85.8 Other specified disorders of bone density and structure
0.732 0.268 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.731 0.269 0.000
R25.2 Cramp and spasm
0.731 0.269 0.000
M25.06 Haemarthrosis (Lower leg)
0.730 0.270 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.728 0.271 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.728 0.272 0.000
F99-F99 Unspecified mental disorder
0.727 0.273 0.000
R23.4 Changes in skin texture
0.726 0.274 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.726 0.274 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.725 0.275 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.725 0.275 0.000
M84 Disorders of continuity of bone
0.724 0.276 0.000
M79.67 Pain in limb (Ankle and foot)
0.723 0.277 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.723 0.277 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.723 0.277 0.000
R23.2 Flushing
0.722 0.278 0.000
M79.10 Myalgia (Multiple sites)
0.721 0.279 0.000
R23.3 Spontaneous ecchymoses
0.721 0.279 0.000
Q60-Q64 Congenital malformations of the urinary system
0.721 0.279 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.720 0.280 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.719 0.281 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.719 0.281 0.000
S27 Injury of other and unspecified intrathoracic organs
0.719 0.281 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.718 0.282 0.000
M23.8 Other internal derangements of knee
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
M79.3 Panniculitis, unspecified
0.717 0.283 0.000
J18.9 Pneumonia, unspecified
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
A00-A09 Intestinal infectious diseases
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
M82 Osteoporosis in diseases classified elsewhere
0.716 0.284 0.000
M79.7 Fibromyalgia
0.715 0.285 0.000
B25-B34 Other viral diseases
0.715 0.285 0.000
M24 Other specific joint derangements
0.714 0.286 0.000
M25.84 Other specified joint disorders (Hand)
0.714 0.286 0.000
Q00-Q07 Congenital malformations of the nervous system
0.712 0.288 0.000
F40.2 Specific (isolated) phobias
0.712 0.288 0.000
Q43.8 Other specified congenital malformations of intestine
0.711 0.289 0.000
T43.6 Psychostimulants with abuse potential
0.711 0.289 0.000
F34 Persistent mood [affective] disorders
0.711 0.289 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.711 0.289 0.000
H70 Mastoiditis and related conditions
0.711 0.289 0.000
H68 Eustachian salpingitis and obstruction
0.711 0.289 0.000
H67 Otitis media in diseases classified elsewhere
0.711 0.289 0.000
H69 Other disorders of Eustachian tube
0.710 0.290 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.710 0.290 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.292 0.000
F38 Other mood [affective] disorders
0.708 0.292 0.000
F39 Unspecified mood [affective] disorder
0.708 0.292 0.000
R06.7 Sneezing
0.707 0.293 0.000
R06.3 Periodic breathing
0.707 0.293 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.293 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.293 0.000
M79.68 Pain in limb (Other)
0.707 0.293 0.000
M79.61 Pain in limb (Shoulder region)
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
Q80-Q89 Other congenital malformations
0.705 0.295 0.000
Y54.3 Benzothiadiazine derivatives
0.703 0.297 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.703 0.297 0.000
M46 Other inflammatory spondylopathies
0.701 0.299 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.701 0.299 0.000
Y52 Agents primarily affecting the cardiovascular system
0.701 0.299 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.700 0.299 0.000
T39.4 Antirheumatics, not elsewhere classified
0.700 0.299 0.000
T39.2 Pyrazolone derivatives
0.700 0.299 0.000
S22.0 Fracture of thoracic vertebra
0.700 0.300 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.699 0.301 0.000
M79.63 Pain in limb (Forearm)
0.696 0.304 0.000
F32.8 Other depressive episodes
0.696 0.304 0.000
F33 Recurrent depressive disorder
0.695 0.305 0.000
R20.3 Hyperaesthesia
0.695 0.305 0.000
R20.1 Hypoaesthesia of skin
0.695 0.305 0.000
R20.0 Anaesthesia of skin
0.695 0.305 0.000
V20-V29 Motorcycle rider injured in transport accident
0.695 0.305 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.694 0.306 0.000
S10-S19 Injuries to the neck
0.693 0.307 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.693 0.307 0.000
A80-A89 Viral infections of the central nervous system
0.693 0.307 0.000
R23.1 Pallor
0.693 0.307 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.692 0.308 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.692 0.308 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.692 0.308 0.000
T42.3 Barbiturates
0.692 0.308 0.000
T42.2 Succinimides and oxazolidinediones
0.692 0.308 0.000
T42.1 Iminostilbenes
0.692 0.308 0.000
T42.0 Hydantoin derivatives
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.692 0.308 0.000
Y10-Y34 Event of undetermined intent
0.692 0.308 0.000
Y00-Y09 Assault
0.692 0.308 0.000
X85-X99 Assault
0.692 0.308 0.000
X30-X39 Exposure to forces of nature
0.692 0.308 0.000
X10-X19 Contact with heat and hot substances
0.692 0.308 0.000
X00-X09 Exposure to smoke, fire and flames
0.692 0.308 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.692 0.308 0.000
W75-W84 Other accidental threats to breathing
0.692 0.308 0.000
W65-W74 Accidental drowning and submersion
0.692 0.308 0.000
V98-V99 Other and unspecified transport accidents
0.692 0.308 0.000
V95-V97 Air and space transport accidents
0.692 0.308 0.000
V90-V94 Water transport accidents
0.692 0.308 0.000
V70-V79 Bus occupant injured in transport accident
0.692 0.308 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.692 0.308 0.000
V01-V09 Pedestrian injured in transport accident
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.691 0.308 0.000
M79.5 Residual foreign body in soft tissue
0.691 0.309 0.000
M25.4 Effusion of joint
0.690 0.310 0.000
Q51 Congenital malformations of uterus and cervix
0.688 0.312 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.687 0.313 0.000
B65-B83 Helminthiases
0.687 0.313 0.000
R26.1 Paralytic gait
0.686 0.314 0.000
R87 Abnormal findings in specimens from female genital organs
0.686 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.314 0.000
R25.1 Tremor, unspecified
0.686 0.314 0.000
Q52 Other congenital malformations of female genitalia
0.686 0.314 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.685 0.314 0.000
R06.6 Hiccough
0.684 0.316 0.000
M35 Other systemic involvement of connective tissue
0.684 0.316 0.000
H65.2 Chronic serous otitis media
0.683 0.316 0.000
F80-F89 Disorders of psychological development
0.683 0.317 0.000
J21 Acute bronchiolitis
0.683 0.317 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.683 0.317 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.683 0.317 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.683 0.317 0.000
M79.04 Rheumatism, unspecified (Hand)
0.683 0.317 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.683 0.317 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.683 0.317 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.683 0.317 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.682 0.317 0.000
Y58 Bacterial vaccines
0.682 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.682 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.682 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.682 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.682 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.317 0.000
Y54.5 Other diuretics
0.681 0.319 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.681 0.319 0.000
M33 Dermatopolymyositis
0.681 0.319 0.000
M32 Systemic lupus erythematosus
0.681 0.319 0.000
M30 Polyarteritis nodosa and related conditions
0.681 0.319 0.000
M79.88 Other specified soft tissue disorders (Other)
0.680 0.320 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.680 0.320 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.680 0.320 0.000
R09.1 Pleurisy
0.680 0.320 0.000
B35-B49 Mycoses
0.679 0.321 0.000
S22.5 Flail chest
0.679 0.321 0.000
R26.0 Ataxic gait
0.679 0.321 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.678 0.322 0.000
Q27 Other congenital malformations of peripheral vascular system
0.678 0.322 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.677 0.323 0.000
S22.3 Fracture of rib
0.676 0.324 0.000
H72.2 Other marginal perforations of tympanic membrane
0.676 0.324 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.676 0.324 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.676 0.324 0.000
F31.8 Other bipolar affective disorders
0.676 0.324 0.000
F31.7 Bipolar affective disorder, currently in remission
0.676 0.324 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.676 0.324 0.000
Q45 Other congenital malformations of digestive system
0.676 0.324 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.676 0.324 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.676 0.324 0.000
Q40 Other congenital malformations of upper alimentary tract
0.676 0.324 0.000
Q39 Congenital malformations of oesophagus
0.676 0.324 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.676 0.324 0.000
H61 Other disorders of external ear
0.676 0.324 0.000
M25.76 Osteophyte (Lower leg)
0.675 0.325 0.000
S29 Other and unspecified injuries of thorax
0.675 0.325 0.000
Y43.4 Immunosuppressive agents
0.675 0.325 0.000
M23.0 Cystic meniscus
0.675 0.325 0.000
R06.4 Hyperventilation
0.674 0.326 0.000
M25.2 Flail joint
0.672 0.328 0.000
M25.1 Fistula of joint
0.672 0.328 0.000
H65.1 Other acute nonsuppurative otitis media
0.671 0.329 0.000
H65.0 Acute serous otitis media
0.671 0.329 0.000
H90-H95 Other disorders of ear
0.670 0.330 0.000
H74.0 Tympanosclerosis
0.670 0.330 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.670 0.330 0.000
A30-A49 Other bacterial diseases
0.669 0.331 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.669 0.331 0.000
T65 Toxic effect of other and unspecified substances
0.668 0.331 0.000
T62 Toxic effect of other noxious substances eaten as food
0.668 0.331 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.668 0.331 0.000
T60 Toxic effect of pesticides
0.668 0.331 0.000
T57 Toxic effect of other inorganic substances
0.668 0.331 0.000
T54 Toxic effect of corrosive substances
0.668 0.331 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.668 0.331 0.000
T52 Toxic effect of organic solvents
0.668 0.331 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.668 0.331 0.000
T58 Toxic effect of carbon monoxide
0.668 0.331 0.000
T55 Toxic effect of soaps and detergents
0.668 0.331 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.667 0.333 0.000
J60-J70 Lung diseases due to external agents
0.666 0.334 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.666 0.334 0.000
S26 Injury of heart
0.666 0.334 0.000
S25 Injury of blood vessels of thorax
0.666 0.334 0.000
S24 Injury of nerves and spinal cord at thorax level
0.666 0.334 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.666 0.334 0.000
S21 Open wound of thorax
0.666 0.334 0.000
M75.3 Calcific tendinitis of shoulder
0.665 0.335 0.000
T63.4 Venom of other arthropods
0.664 0.336 0.000
M75.2 Bicipital tendinitis
0.664 0.336 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.662 0.338 0.000
Q18 Other congenital malformations of face and neck
0.662 0.338 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.660 0.339 0.000
M66 Spontaneous rupture of synovium and tendon
0.660 0.340 0.000
Q23 Congenital malformations of aortic and mitral valves
0.660 0.340 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.658 0.342 0.000
H80-H83 Diseases of inner ear
0.658 0.342 0.000
T14 Injury of unspecified body region
0.657 0.343 0.000
R23.0 Cyanosis
0.656 0.344 0.000
J20.9 Acute bronchitis, unspecified
0.655 0.345 0.000
S90-S99 Injuries to the ankle and foot
0.654 0.346 0.000
Y40 Systemic antibiotics
0.654 0.346 0.000
W22 Striking against or struck by other objects
0.654 0.346 0.000
J80 Adult respiratory distress syndrome
0.654 0.346 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.654 0.346 0.000
V10-V19 Pedal cyclist injured in transport accident
0.653 0.346 0.000
Y42.9 Other and unspecified hormone antagonists
0.653 0.347 0.000
Y42.4 Oral contraceptives
0.653 0.347 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.653 0.347 0.000
Y42.2 Antithyroid drugs
0.653 0.347 0.000
Y42.1 Thyroid hormones and substitutes
0.653 0.347 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.653 0.347 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.651 0.348 0.000
H72.8 Other perforations of tympanic membrane
0.651 0.349 0.000
J14 Pneumonia due to Haemophilus influenzae
0.651 0.349 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.651 0.349 0.000
X50-X57 Overexertion, travel and privation
0.651 0.349 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.650 0.350 0.000
M23.9 Internal derangement of knee, unspecified
0.648 0.352 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.648 0.352 0.000
M83 Adult osteomalacia
0.642 0.357 0.000
R22.1 Localised swelling, mass and lump, neck
0.642 0.358 0.000
R47.0 Dysphasia and aphasia
0.641 0.359 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.641 0.359 0.000
H73.1 Chronic myringitis
0.641 0.359 0.000
H73.0 Acute myringitis
0.641 0.359 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.640 0.360 0.000
J17 Pneumonia in diseases classified elsewhere
0.639 0.361 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.639 0.361 0.000
J12 Viral pneumonia, not elsewhere classified
0.639 0.361 0.000
J09 Influenza due to certain identified influenza virus
0.639 0.361 0.000
H72.1 Attic perforation of tympanic membrane
0.639 0.361 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.638 0.361 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.638 0.362 0.000
B50-B64 Protozoal diseases
0.637 0.363 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.637 0.363 0.000
T59 Toxic effect of other gases, fumes and vapours
0.636 0.364 0.000
J15.8 Other bacterial pneumonia
0.636 0.364 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.635 0.365 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.635 0.365 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.635 0.365 0.000
H72.0 Central perforation of tympanic membrane
0.635 0.365 0.000
M71 Other bursopathies
0.634 0.366 0.000
S22.9 Fracture of bony thorax, part unspecified
0.634 0.366 0.000
S22.8 Fracture of other parts of bony thorax
0.634 0.366 0.000
R27.8 Other and unspecified lack of coordination
0.633 0.366 0.000
M84.0 Malunion of fracture
0.633 0.367 0.000
Q43.7 Persistent cloaca
0.633 0.367 0.000
Q43.6 Congenital fistula of rectum and anus
0.633 0.367 0.000
Q43.5 Ectopic anus
0.633 0.367 0.000
Q43.4 Duplication of intestine
0.633 0.367 0.000
Q43.3 Congenital malformations of intestinal fixation
0.633 0.367 0.000
Q43.2 Other congenital functional disorders of colon
0.633 0.367 0.000
Q43.1 Hirschsprung's disease
0.633 0.367 0.000
M40-M43 Deforming dorsopathies
0.633 0.367 0.000
V40-V49 Car occupant injured in transport accident
0.633 0.367 0.000
Q53 Undescended testicle
0.632 0.367 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.632 0.368 0.000
T43.9 Psychotropic drug, unspecified
0.631 0.368 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.631 0.368 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.631 0.368 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.631 0.368 0.000
F69 Unspecified disorder of adult personality and behaviour
0.631 0.369 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.631 0.369 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.631 0.369 0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.631 0.369 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.631 0.369 0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.631 0.369 0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.631 0.369 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.631 0.369 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.631 0.369 0.000
J18.8 Other pneumonia, organism unspecified
0.631 0.369 0.000
J18.2 Hypostatic pneumonia, unspecified
0.631 0.369 0.000
S40-S49 Injuries to the shoulder and upper arm
0.631 0.369 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.630 0.370 0.000
R06.1 Stridor
0.630 0.370 0.000
M25.3 Other instability of joint
0.629 0.371 0.000
S22.1 Multiple fractures of thoracic spine
0.629 0.371 0.000
M85.6 Other cyst of bone
0.629 0.371 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.629 0.371 0.000
M87 Osteonecrosis
0.629 0.371 0.000
V80-V89 Other land transport accidents
0.628 0.372 0.000
M92 Other juvenile osteochondrosis
0.628 0.372 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.627 0.373 0.000
T43.2 Other and unspecified antidepressants
0.626 0.374 0.000
Y57.9 Drug or medicament, unspecified
0.626 0.374 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.626 0.374 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.624 0.376 0.000
T13 Other injuries of lower limb, level unspecified
0.624 0.376 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.624 0.376 0.000
M34 Systemic sclerosis
0.623 0.377 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.623 0.377 0.000
B99-B99 Other infectious diseases
0.622 0.378 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.622 0.378 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.622 0.378 0.000
A75-A79 Rickettsioses
0.622 0.378 0.000
A70-A74 Other diseases caused by chlamydiae
0.622 0.378 0.000
A65-A69 Other spirochaetal diseases
0.622 0.378 0.000
A20-A28 Certain zoonotic bacterial diseases
0.622 0.378 0.000
A15-A19 Tuberculosis
0.622 0.378 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.621 0.379 0.000
M12 Other specific arthropathies
0.621 0.379 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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