TreeWAS – Variant ID: rs76264592

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
E11.9 Without complications	1.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
E03.9 Hypothyroidism, unspecified	0.994	0.006
E03 Other hypothyroidism	0.992	0.008
E00-E07 Disorders of thyroid gland	0.992	0.008
Chapter IV Endocrine, nutritional and metabolic diseases	0.991	0.009
E14 Unspecified diabetes mellitus	0.981	0.019
E10 Insulin-dependent diabetes mellitus	0.960	0.040
E14.9 Without complications	0.946	0.054
E10.9 Without complications	0.933	0.067
E11.2 With renal complications	0.928	0.072
E14.3 With ophthalmic complications	0.875	0.125
E04 Other non-toxic goitre	0.866	0.134
E11.3 With ophthalmic complications	0.856	0.144
E04.2 Non-toxic multinodular goitre	0.838	0.162
E13 Other specified diabetes mellitus	0.830	0.170
E11.1 With ketoacidosis	0.801	0.199
E10.8 With unspecified complications	0.799	0.201
E11.0 With coma	0.755	0.245
E10.2 With renal complications	0.755	0.245
E10.0 With coma	0.741	0.259
E05 Thyrotoxicosis [hyperthyroidism]	0.729	0.271
E11.7 With multiple complications	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
E03.5 Myxoedema coma	0.711	0.288
E03.4 Atrophy of thyroid (acquired)	0.711	0.288
E03.3 Postinfectious hypothyroidism	0.711	0.288
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.711	0.288
E03.1 Congenital hypothyroidism without goitre	0.711	0.288
E03.0 Congenital hypothyroidism with diffuse goitre	0.711	0.288
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.711	0.289
E00 Congenital iodine-deficiency syndrome	0.711	0.289
E02 Subclinical iodine-deficiency hypothyroidism	0.711	0.289
E13.9 Without complications	0.708	0.291
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.708	0.292
E50-E64 Other nutritional deficiencies	0.705	0.295
E14.8 With unspecified complications	0.703	0.296
E14.7 With multiple complications	0.703	0.296
E14.6 With other specified complications	0.703	0.296
E14.5 With peripheral circulatory complications	0.703	0.296
E14.4 With neurological complications	0.703	0.296
E14.2 Withrenal complications	0.703	0.296
E14.1 With ketoacidosis	0.703	0.296
E14.0 With coma	0.703	0.296
E65-E68 Obesity and other hyperalimentation	0.702	0.298
E07 Other disorders of thyroid	0.690	0.310
E10.7 With multiple complications	0.688	0.311
E10.6 With other specified complications	0.688	0.311
E11.6 With other specified complications	0.671	0.329
E40-E46 Malnutrition	0.661	0.339
E11.8 With unspecified complications	0.654	0.346
E11.4 With neurological complications	0.653	0.347
E03.8 Other specified hypothyroidism	0.652	0.348
E10.3 With ophthalmic complications	0.652	0.348
E10.5 With peripheral circulatory complications	0.650	0.350
E04.0 Non-toxic diffuse goitre	0.629	0.371
E10.1 With ketoacidosis	0.623	0.377
E04.8 Other specified non-toxic goitre	0.621	0.379
E05.9 Thyrotoxicosis, unspecified	0.604	0.396
E13.8 With unspecified complications	0.595	0.405
E13.7 With multiple complications	0.595	0.405
E13.6 With other specified complications	0.595	0.405
E13.5 With peripheral circulatory complications	0.595	0.405
E13.4 With neurological complications	0.595	0.405
E13.3 With ophthalmic complications	0.595	0.405
E13.2 With renal complications	0.595	0.405
E13.1 With ketoacidosis	0.595	0.405
E13.0 With coma	0.595	0.405
E06 Thyroiditis	0.572	0.428
E65 Localised adiposity	0.568	0.432
E20-E35 Disorders of other endocrine glands	0.560	0.440
E11.5 With peripheral circulatory complications	0.550	0.449
E61 Deficiency of other nutrient elements	0.526	0.474
E05.8 Other thyrotoxicosis	0.523	0.477
E05.5 Thyroid crisis or storm	0.523	0.477
E05.4 Thyrotoxicosis factitia	0.523	0.477
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.523	0.477
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.523	0.477
E07.8 Other specified disorders of thyroid	0.518	0.482
E12.9 Without complications	0.514	0.486
E12.8 With unspecified complications	0.514	0.486
E12.7 With multiple complications	0.514	0.486
E12.6 With other specified complications	0.514	0.486
E12.5 With peripheral circulatory complications	0.514	0.486
E12.4 With neurological complications	0.514	0.486
E12.3 With ophthalmic complications	0.514	0.486
E12.2 With renal complications	0.514	0.486
E12.1 With ketoacidosis	0.514	0.486
E12.0 With coma	0.514	0.486
E04.1 Non-toxic single thyroid nodule	0.514	0.486
E55 Vitamin D deficiency	0.512	0.488
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.510	0.490
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.510	0.490
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.510	0.490
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.510	0.490
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.510	0.490
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.510	0.490
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.510	0.490
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.510	0.490
E15 Nondiabetic hypoglycaemic coma	0.508	0.492
E64 Sequelae of malnutrition and other nutritional deficiencies	0.505	0.494
E63 Other nutritional deficiencies	0.505	0.494
E56 Other vitamin deficiencies	0.505	0.494
E51 Thiamine deficiency	0.505	0.494
E50 Vitamin A deficiency	0.505	0.494
E60 Dietary zinc deficiency	0.505	0.494
E59 Dietary selenium deficiency	0.505	0.494
E58 Dietary calcium deficiency	0.505	0.494
E54 Ascorbic acid deficiency	0.505	0.494
E52 Niacin deficiency [pellagra]	0.505	0.494
E16 Other disorders of pancreatic internal secretion	0.505	0.495
E05.0 Thyrotoxicosis with diffuse goitre	0.504	0.495
E67 Other hyperalimentation	0.503	0.496
E68 Sequelae of hyperalimentation	0.503	0.496
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.502	0.498
E07.1 Dyshormogenetic goitre	0.495	0.505
E07.0 Hypersecretion of calcitonin	0.495	0.505
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.487	0.513
E10.4 With neurological complications	0.480	0.519
E44 Protein-energy malnutrition of moderate and mild degree	0.474	0.526
E45 Retarded development following protein-energy malnutrition	0.474	0.526
E43 Unspecified severe protein-energy malnutrition	0.474	0.526
E42 Marasmic kwashiorkor	0.474	0.526
E41 Nutritional marasmus	0.474	0.526
E40 Kwashiorkor	0.474	0.526
E53 Deficiency of other B group vitamins	0.469	0.531
T36-T50 Poisoning by drugs, medicaments and biological substances	0.468	0.532
E22 Hyperfunction of pituitary gland	0.447	0.553
E07.9 Disorder of thyroid, unspecified	0.445	0.555
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.444	0.556
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.430	0.570
E46 Unspecified protein-energy malnutrition	0.424	0.575
E61.2 Magnesium deficiency	0.421	0.579
E28 Ovarian dysfunction	0.412	0.588
E06.5 Other chronic thyroiditis	0.410	0.589
E06.4 Drug-induced thyroiditis	0.410	0.589
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.410	0.589
E06.1 Subacute thyroiditis	0.410	0.589
E06.0 Acute thyroiditis	0.410	0.589
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.405	0.595
E34 Other endocrine disorders	0.404	0.596
E29 Testicular dysfunction	0.403	0.597
E35 Disorders of endocrine glands in diseases classified elsewhere	0.402	0.598
E32 Diseases of thymus	0.402	0.598
E31 Polyglandular dysfunction	0.402	0.598
E30 Disorders of puberty, not elsewhere classified	0.402	0.598
E27 Other disorders of adrenal gland	0.402	0.598
E25 Adrenogenital disorders	0.402	0.598
E20 Hypoparathyroidism	0.402	0.598
T46 Poisoning by agents primarily affecting the cardiovascular system	0.400	0.600
# Top node	0.399	0.601
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.398	0.602
S90-S99 Injuries to the ankle and foot	0.398	0.602
Chapter V Mental and behavioural disorders	0.397	0.603
S92 Fracture of foot, except ankle	0.396	0.604
T43.2 Other and unspecified antidepressants	0.395	0.605
E66 Obesity	0.395	0.605
T42.4 Benzodiazepines	0.393	0.607
F60-F69 Disorders of adult personality and behaviour	0.391	0.609
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.388	0.611
M65-M68 Disorders of synovium and tendon	0.379	0.621
S92.0 Fracture of calcaneus	0.379	0.621
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.378	0.622
E61.9 Deficiency of nutrient element, unspecified	0.377	0.623
E61.8 Deficiency of other specified nutrient elements	0.377	0.623
E61.7 Deficiency of multiple nutrient elements	0.377	0.623
E61.6 Vanadium deficiency	0.377	0.623
E61.5 Molybdenum deficiency	0.377	0.623
E61.4 Chromium deficiency	0.377	0.623
E61.3 Manganese deficiency	0.377	0.623
E61.0 Copper deficiency	0.377	0.623
F60 Specific personality disorders	0.376	0.624
M86-M90 Other osteopathies	0.375	0.625
M80-M85 Disorders of bone density and structure	0.375	0.625
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.374	0.626
E55.9 Vitamin D deficiency, unspecified	0.373	0.627
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.371	0.629
M65 Synovitis and tenosynovitis	0.369	0.631
E16.1 Other hypoglycaemia	0.368	0.632
S92.00 Fracture of calcaneus (closed)	0.367	0.633
E55.0 Rickets, active	0.367	0.633
F40-F48 Neurotic, stress-related and somatoform disorders	0.364	0.636
S92.3 Fracture of metatarsal bone	0.363	0.637
E50.9 Vitamin A deficiency, unspecified	0.362	0.637
E50.8 Other manifestations of vitamin A deficiency	0.362	0.637
E50.7 Other ocular manifestations of vitamin A deficiency	0.362	0.637
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.362	0.637
E50.5 Vitamin A deficiency with night blindness	0.362	0.637
E50.4 Vitamin A deficiency with keratomalacia	0.362	0.637
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.362	0.637
E50.2 Vitamin A deficiency with corneal xerosis	0.362	0.637
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.362	0.637
E50.0 Vitamin A deficiency with conjunctival xerosis	0.362	0.637
E51.9 Thiamine deficiency, unspecified	0.362	0.637
E51.8 Other manifestations of thiamine deficiency	0.362	0.637
E51.2 Wernicke's encephalopathy	0.362	0.637
E51.1 Beriberi	0.362	0.637
E56.9 Vitamin deficiency, unspecified	0.362	0.637
E56.8 Deficiency of other vitamins	0.362	0.637
E56.1 Deficiency of vitamin K	0.362	0.637
E56.0 Deficiency of vitamin E	0.362	0.637
E63.9 Nutritional deficiency, unspecified	0.362	0.637
E63.8 Other specified nutritional deficiencies	0.362	0.637
E63.1 Imbalance of constituents of food intake	0.362	0.637
E63.0 Essential fatty acid [EFA] deficiency	0.362	0.637
E64.9 Sequelae of unspecified nutritional deficiency	0.362	0.637
E64.8 Sequelae of other nutritional deficiencies	0.362	0.637
E64.3 Sequelae of rickets	0.362	0.637
E64.2 Sequelae of vitamin C deficiency	0.362	0.637
E64.1 Sequelae of vitamin A deficiency	0.362	0.637
E64.0 Sequelae of protein-energy malnutrition	0.362	0.637
E16.9 Disorder of pancreatic internal secretion, unspecified	0.362	0.638
E16.8 Other specified disorders of pancreatic internal secretion	0.362	0.638
E16.4 Abnormal secretion of gastrin	0.362	0.638
E16.3 Increased secretion of glucagon	0.362	0.638
E67.8 Other specified hyperalimentation	0.361	0.639
E67.3 Hypervitaminosis D	0.361	0.639
E67.2 Megavitamin-B6 syndrome	0.361	0.639
E67.1 Hypercarotenaemia	0.361	0.639
E67.0 Hypervitaminosis A	0.361	0.639
E16.2 Hypoglycaemia, unspecified	0.361	0.639
M05-M14 Inflammatory polyarthropathies	0.358	0.642
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.358	0.642
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.356	0.644
E16.0 Drug-induced hypoglycaemia without coma	0.353	0.646
E06.3 Autoimmune thyroiditis	0.353	0.647
M65.9 Synovitis and tenosynovitis, unspecified	0.353	0.647
F60.9 Personality disorder, unspecified	0.353	0.647
E26 Hyperaldosteronism	0.351	0.649
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.350	0.650
E06.9 Thyroiditis, unspecified	0.350	0.650
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.350	0.650
T42.5 Mixed antiepileptics, not elsewhere classified	0.350	0.650
T42.3 Barbiturates	0.350	0.650
T42.2 Succinimides and oxazolidinediones	0.350	0.650
T42.1 Iminostilbenes	0.350	0.650
T42.0 Hydantoin derivatives	0.350	0.650
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.349	0.651
E24 Cushing's syndrome	0.349	0.651
F69 Unspecified disorder of adult personality and behaviour	0.348	0.652
T43.5 Other and unspecified antipsychotics and neuroleptics	0.345	0.655
E61.1 Iron deficiency	0.344	0.655
Chapter XII Diseases of the skin and subcutaneous tissue	0.343	0.657
E44.1 Mild protein-energy malnutrition	0.340	0.660
E44.0 Moderate protein-energy malnutrition	0.340	0.660
M85 Other disorders of bone density and structure	0.340	0.660
S92.30 Fracture of metatarsal bone (closed)	0.340	0.660
F40 Phobic anxiety disorders	0.337	0.663
T43.4 Butyrophenone and thioxanthene neuroleptics	0.337	0.663
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.336	0.663
E53.9 Vitamin B deficiency, unspecified	0.336	0.664
E53.1 Pyridoxine deficiency	0.336	0.664
E53.0 Riboflavin deficiency	0.336	0.664
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.336	0.664
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.336	0.664
T41 Poisoning by anaesthetics and therapeutic gases	0.336	0.664
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.336	0.664
T36 Poisoning by systemic antibiotics	0.336	0.664
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.336	0.664
L20-L30 Dermatitis and eczema	0.336	0.664
E28.3 Primary ovarian failure	0.335	0.665
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.331	0.669
E66.8 Other obesity	0.331	0.669
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.330	0.670
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.330	0.670
F60.3 Emotionally unstable personality disorder	0.329	0.671
F80-F89 Disorders of psychological development	0.329	0.671
S92.2 Fracture of other tarsal bone(s)	0.328	0.672
E22.0 Acromegaly and pituitary gigantism	0.328	0.672
F43 Reaction to severe stress, and adjustment disorders	0.327	0.673
M06 Other rheumatoid arthritis	0.327	0.673
M15-M19 Arthrosis	0.326	0.674
T46.1 Calcium-channel blockers	0.325	0.675
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.324	0.676
T46.5 Other antihypertensive drugs, not elsewhere classified	0.323	0.677
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.323	0.677
E27.4 Other and unspecified adrenocortical insufficiency	0.322	0.678
E22.9 Hyperfunction of pituitary gland, unspecified	0.321	0.679
E22.8 Other hyperfunction of pituitary gland	0.321	0.679
M89 Other disorders of bone	0.321	0.679
M60-M63 Disorders of muscles	0.319	0.681
T20-T25 Burns and corrosions of external body surface, specified by site	0.318	0.682
L29 Pruritus	0.317	0.683
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.317	0.683
M19 Other arthrosis	0.316	0.684
Q20-Q28 Congenital malformations of the circulatory system	0.316	0.684
S97 Crushing injury of ankle and foot	0.315	0.685
T00-T07 Injuries involving multiple body regions	0.315	0.685
E23 Hypofunction and other disorders of pituitary gland	0.311	0.688
M86 Osteomyelitis	0.311	0.689
M90 Osteopathies in diseases classified elsewhere	0.311	0.689
M65.1 Other infective (teno)synovitis	0.311	0.689
M19.9 Arthrosis, unspecified	0.310	0.690
E04.9 Non-toxic goitre, unspecified	0.309	0.691
T45.1 Antineoplastic and immunosuppressive drugs	0.309	0.691
T43.9 Psychotropic drug, unspecified	0.308	0.691
T43.8 Other psychotropic drugs, not elsewhere classified	0.308	0.691
T43.6 Psychostimulants with abuse potential	0.308	0.691
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.308	0.691
F40.2 Specific (isolated) phobias	0.308	0.692
M81 Osteoporosis without pathological fracture	0.305	0.695
E22.1 Hyperprolactinaemia	0.305	0.695
F44 Dissociative [conversion] disorders	0.304	0.696
T46.4 Angiotensin-converting-enzyme inhibitors	0.304	0.696
M05 Seropositive rheumatoid arthritis	0.303	0.697
E27.9 Disorder of adrenal gland, unspecified	0.302	0.698
M87 Osteonecrosis	0.302	0.698
S92.5 Fracture of other toe	0.301	0.699
M06.9 Rheumatoid arthritis, unspecified	0.300	0.700
E53.8 Deficiency of other specified B group vitamins	0.300	0.700
T38.1 Thyroid hormones and substitutes	0.298	0.702
M85.0 Fibrous dysplasia (monostotic)	0.298	0.702
Q60-Q64 Congenital malformations of the urinary system	0.297	0.702
L40-L45 Papulosquamous disorders	0.297	0.703
T45.5 Anticoagulants	0.296	0.703
M00-M03 Infectious arthropathies	0.296	0.704
E28.9 Ovarian dysfunction, unspecified	0.296	0.704
E28.8 Other ovarian dysfunction	0.296	0.704
E28.1 Androgen excess	0.296	0.704
E28.0 Oestrogen excess	0.296	0.704
M19.93 Arthrosis, unspecified (Forearm)	0.296	0.704
S31 Open wound of abdomen, lower back and pelvis	0.296	0.704
F99-F99 Unspecified mental disorder	0.295	0.704
E34.8 Other specified endocrine disorders	0.295	0.705
L27 Dermatitis due to substances taken internally	0.295	0.705
M19.99 Arthrosis, unspecified (Site unspecified)	0.295	0.705
T63 Toxic effect of contact with venomous animals	0.294	0.706
T43.0 Tricyclic and tetracyclic antidepressants	0.292	0.708
T33-T35 Frostbite	0.290	0.710
T26-T28 Burns and corrosions confined to eye and internal organs	0.290	0.710
E29.1 Testicular hypofunction	0.290	0.710
M45-M49 Spondylopathies	0.290	0.710
E34.5 Androgen resistance syndrome	0.290	0.710
E34.4 Constitutional tall stature	0.290	0.710
E34.3 Short stature, not elsewhere classified	0.290	0.710
E34.2 Ectopic hormone secretion, not elsewhere classified	0.290	0.710
E34.1 Other hypersecretion of intestinal hormones	0.290	0.710
E34.0 Carcinoid syndrome	0.290	0.710
F43.9 Reaction to severe stress, unspecified	0.290	0.710
L29.9 Pruritus, unspecified	0.289	0.711
E29.9 Testicular dysfunction, unspecified	0.289	0.711
E29.8 Other testicular dysfunction	0.289	0.711
E29.0 Testicular hyperfunction	0.289	0.711
E20.9 Hypoparathyroidism, unspecified	0.288	0.712
E20.8 Other hypoparathyroidism	0.288	0.712
E20.1 Pseudohypoparathyroidism	0.288	0.712
E20.0 Idiopathic hypoparathyroidism	0.288	0.712
E25.9 Adrenogenital disorder, unspecified	0.288	0.712
E25.8 Other adrenogenital disorders	0.288	0.712
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.288	0.712
E30.9 Disorder of puberty, unspecified	0.288	0.712
E30.8 Other disorders of puberty	0.288	0.712
E30.1 Precocious puberty	0.288	0.712
E30.0 Delayed puberty	0.288	0.712
E31.9 Polyglandular dysfunction, unspecified	0.288	0.712
E31.8 Other polyglandular dysfunction	0.288	0.712
E31.1 Polyglandular hyperfunction	0.288	0.712
E31.0 Autoimmune polyglandular failure	0.288	0.712
E32.9 Disease of thymus, unspecified	0.288	0.712
E32.8 Other diseases of thymus	0.288	0.712
E32.1 Abscess of thymus	0.288	0.712
E32.0 Persistent hyperplasia of thymus	0.288	0.712
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.288	0.712
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.288	0.712
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.288	0.712
E27.5 Adrenomedullary hyperfunction	0.288	0.712
E27.3 Drug-induced adrenocortical insufficiency	0.288	0.712
E27.2 Addisonian crisis	0.288	0.712
E27.0 Other adrenocortical overactivity	0.288	0.712
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.287	0.713
T46.8 Antivaricose drugs, including sclerosing agents	0.287	0.713
T46.7 Peripheral vasodilators	0.287	0.713
T46.3 Coronary vasodilators, not elsewhere classified	0.287	0.713
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.287	0.713
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.287	0.713
M85.6 Other cyst of bone	0.287	0.713
S92.7 Multiple fractures of foot	0.287	0.713
S91 Open wound of ankle and foot	0.287	0.713
S10-S19 Injuries to the neck	0.286	0.713
E34.9 Endocrine disorder, unspecified	0.286	0.714
Chapter XVI Certain conditions originating in the perinatal period	0.286	0.714
F10 Mental and behavioural disorders due to use of alcohol	0.286	0.714
S98 Traumatic amputation of ankle and foot	0.285	0.715
S96 Injury of muscle and tendon at ankle and foot level	0.285	0.715
S95 Injury of blood vessels at ankle and foot level	0.285	0.715
S94 Injury of nerves at ankle and foot level	0.285	0.715
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.285	0.715
F70-F79 Mental retardation	0.285	0.715
S92.9 Fracture of foot, unspecified	0.284	0.716
S92.4 Fracture of great toe	0.284	0.716
T15-T19 Effects of foreign body entering through natural orifice	0.284	0.716
M84 Disorders of continuity of bone	0.283	0.716
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.283	0.717
E66.2 Extreme obesity with alveolar hypoventilation	0.283	0.717
E66.1 Drug-induced obesity	0.283	0.717
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.283	0.717
M65.3 Trigger finger	0.282	0.718
T59 Toxic effect of other gases, fumes and vapours	0.282	0.718
S40-S49 Injuries to the shoulder and upper arm	0.282	0.718
M19.98 Arthrosis, unspecified (Other)	0.281	0.719
M80 Osteoporosis with pathological fracture	0.281	0.719
F68 Other disorders of adult personality and behaviour	0.280	0.720
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.280	0.720
F65 Disorders of sexual preference	0.280	0.720
F64 Gender identity disorders	0.280	0.720
F63 Habit and impulse disorders	0.280	0.720
F62 Enduring personality changes, not attributable to brain damage and disease	0.280	0.720
F61 Mixed and other personality disorders	0.280	0.720
S92.20 Fracture of other tarsal bone(s) (closed)	0.279	0.720
E21.5 Disorder of parathyroid gland, unspecified	0.279	0.721
E21.4 Other specified disorders of parathyroid gland	0.279	0.721
E21.2 Other hyperparathyroidism	0.279	0.721
E27.1 Primary adrenocortical insufficiency	0.278	0.722
M13 Other arthritis	0.276	0.724
F43.2 Adjustment disorders	0.275	0.725
F84 Pervasive developmental disorders	0.275	0.725
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.275	0.725
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.274	0.726
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.274	0.726
F40.8 Other phobic anxiety disorders	0.274	0.726
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.274	0.726
S70-S79 Injuries to the hip and thigh	0.273	0.727
T43.3 Phenothiazine antipsychotics and neuroleptics	0.273	0.727
F30-F39 Mood [affective] disorders	0.273	0.727
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.272	0.728
S92.01 Fracture of calcaneus (open)	0.272	0.728
M82 Osteoporosis in diseases classified elsewhere	0.272	0.728
T45.9 Primarily systemic and haematological agent, unspecified	0.271	0.729
T45.8 Other primarily systemic and haematological agents	0.271	0.729
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.271	0.729
T45.6 Fibrinolysis-affecting drugs	0.271	0.729
T45.4 Iron and its compounds	0.271	0.729
T45.3 Enzymes, not elsewhere classified	0.271	0.729
T45.2 Vitamins, not elsewhere classified	0.271	0.729
F43.1 Posttraumatic stress disorder	0.271	0.729
L60-L75 Disorders of skin appendages	0.271	0.729
L27.0 Generalised skin eruption due to drugs and medicaments	0.270	0.730
F60.8 Other specific personality disorders	0.270	0.730
F60.7 Dependent personality disorder	0.270	0.730
F60.6 Anxious [avoidant] personality disorder	0.270	0.730
F60.5 Anankastic personality disorder	0.270	0.730
F60.4 Histrionic personality disorder	0.270	0.730
F60.2 Dissocial personality disorder	0.270	0.730
F60.1 Schizoid personality disorder	0.270	0.730
F60.0 Paranoid personality disorder	0.270	0.730
M65.14 Other infective (teno)synovitis (Hand)	0.269	0.730
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.269	0.731
L29.2 Pruritus vulvae	0.269	0.731
M89.8 Other specified disorders of bone	0.269	0.731
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.269	0.731
M83 Adult osteomalacia	0.269	0.731
M67 Other disorders of synovium and tendon	0.269	0.731
Q21 Congenital malformations of cardiac septa	0.268	0.732
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.268	0.732
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.268	0.732
M48 Other spondylopathies	0.267	0.733
M19.1 Posttraumatic arthrosis of other joints	0.267	0.733
M65.8 Other synovitis and tenosynovitis	0.266	0.734
L28 Lichen simplex chronicus and prurigo	0.266	0.734
T56 Toxic effect of metals	0.266	0.734
M90.7 Fracture of bone in neoplastic disease	0.266	0.734
T11 Other injuries of upper limb, level unspecified	0.265	0.735
F10.0 Acute intoxication	0.265	0.735
T58 Toxic effect of carbon monoxide	0.265	0.735
M65.2 Calcific tendinitis	0.265	0.735
M65.0 Abscess of tendon sheath	0.265	0.735
S92.1 Fracture of talus	0.264	0.735
L40 Psoriasis	0.264	0.736
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.264	0.736
E66.0 Obesity due to excess calories	0.263	0.737
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.263	0.737
M05.9 Seropositive rheumatoid arthritis, unspecified	0.263	0.737
F81 Specific developmental disorders of scholastic skills	0.263	0.737
M62 Other disorders of muscle	0.263	0.737
T51 Toxic effect of alcohol	0.262	0.738
F48 Other neurotic disorders	0.261	0.738
T40.6 Other and unspecified narcotics	0.261	0.739
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.261	0.739
M91-M94 Chondropathies	0.261	0.739
S92.31 Fracture of metatarsal bone (open)	0.260	0.739
M65.4 Radial styloid tenosynovitis [de Quervain]	0.259	0.741
M15 Polyarthrosis	0.259	0.741
E21.3 Hyperparathyroidism, unspecified	0.259	0.741
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.258	0.742
Q00-Q07 Congenital malformations of the nervous system	0.258	0.742
Q23 Congenital malformations of aortic and mitral valves	0.257	0.743
M06.3 Rheumatoid nodule	0.257	0.743
M12 Other specific arthropathies	0.257	0.743
M09 Juvenile arthritis in diseases classified elsewhere	0.257	0.743
M08 Juvenile arthritis	0.257	0.743
S31.0 Open wound of lower back and pelvis	0.257	0.743
T38.9 Other and unspecified hormone antagonists	0.257	0.743
T38.8 Other and unspecified hormones and their synthetic substitutes	0.257	0.743
T38.7 Androgens and anabolic congeners	0.257	0.743
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.257	0.743
T38.5 Other oestrogens and progestogens	0.257	0.743
T38.4 Oral contraceptives	0.257	0.743
T38.2 Antithyroid drugs	0.257	0.743
T38.0 Glucocorticoids and synthetic analogues	0.257	0.743

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations