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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76542212
log Bayes Factor = 5.89986
Chromosome 6   position 28,198,122  (GRCh37) Explore rs76542212 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
E83 Disorders of mineral metabolism
0.000 0.001 0.999
K90.0 Coeliac disease
0.000 0.002 0.998
E70-E90 Metabolic disorders
0.000 0.004 0.996
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.006 0.994
E87.5 Hyperkalaemia
0.000 0.025 0.975
E87.2 Acidosis
0.000 0.028 0.972
E83.5 Disorders of calcium metabolism
0.000 0.038 0.962
E87.7 Fluid overload
0.000 0.117 0.883
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.118 0.882
E88 Other metabolic disorders
0.000 0.154 0.846
E89.0 Postprocedural hypothyroidism
0.000 0.171 0.829
E87.0 Hyperosmolality and hypernatraemia
0.000 0.205 0.795
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.206 0.794
E10-E14 Diabetes mellitus
0.000 0.211 0.789
E10 Insulin-dependent diabetes mellitus
0.000 0.220 0.780
E83.4 Disorders of magnesium metabolism
0.000 0.229 0.771
E10.9 Without complications
0.000 0.250 0.750
E87.3 Alkalosis
0.000 0.255 0.745
E14 Unspecified diabetes mellitus
0.000 0.256 0.744
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.262 0.738
E83.3 Disorders of phosphorus metabolism
0.000 0.271 0.729
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.284 0.716
E83.8 Other disorders of mineral metabolism
0.000 0.284 0.716
E83.2 Disorders of zinc metabolism
0.000 0.284 0.716
E83.0 Disorders of copper metabolism
0.000 0.284 0.716
E84 Cystic fibrosis
0.000 0.286 0.714
E79 Disorders of purine and pyrimidine metabolism
0.000 0.286 0.714
E77 Disorders of glycoprotein metabolism
0.000 0.286 0.714
E76 Disorders of glycosaminoglycan metabolism
0.000 0.286 0.714
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.286 0.714
E72 Other disorders of amino-acid metabolism
0.000 0.286 0.714
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.286 0.714
E70 Disorders of aromatic amino-acid metabolism
0.000 0.286 0.714
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.286 0.714
E87.4 Mixed disorder of acid-base balance
0.000 0.287 0.713
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.291 0.709
E14.9 Without complications
0.000 0.295 0.705
E85 Amyloidosis
0.000 0.295 0.705
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.302 0.698
E10.3 With ophthalmic complications
0.000 0.309 0.691
E86 Volume depletion
0.000 0.310 0.690
E74 Other disorders of carbohydrate metabolism
0.000 0.328 0.672
E87.6 Hypokalaemia
0.000 0.351 0.649
K90 Intestinal malabsorption
0.000 0.358 0.642
E73 Lactose intolerance
0.000 0.364 0.636
E10.4 With neurological complications
0.000 0.365 0.635
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.367 0.632
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.367 0.632
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.367 0.632
E89.5 Postprocedural testicular hypofunction
0.000 0.367 0.632
E89.4 Postprocedural ovarian failure
0.000 0.367 0.632
E89.1 Postprocedural hypoinsulinaemia
0.000 0.367 0.632
E16 Other disorders of pancreatic internal secretion
0.000 0.370 0.630
E40-E46 Malnutrition
0.000 0.374 0.626
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.385 0.615
E89.2 Postprocedural hypoparathyroidism
0.000 0.392 0.608
E88.9 Metabolic disorder, unspecified
0.000 0.393 0.606
E88.8 Other specified metabolic disorders
0.000 0.393 0.606
E88.3 Tumour lysis syndrome
0.000 0.393 0.606
E88.2 Lipomatosis, not elsewhere classified
0.000 0.393 0.606
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.393 0.606
E10.1 With ketoacidosis
0.000 0.400 0.600
E13 Other specified diabetes mellitus
0.000 0.401 0.599
E16.2 Hypoglycaemia, unspecified
0.000 0.403 0.597
E14.3 With ophthalmic complications
0.000 0.428 0.572
E10.5 With peripheral circulatory complications
0.000 0.429 0.571
E12 Malnutrition-related diabetes mellitus
0.000 0.434 0.566
E10.8 With unspecified complications
0.000 0.440 0.560
E10.7 With multiple complications
0.000 0.440 0.560
E10.6 With other specified complications
0.000 0.440 0.560
E10.0 With coma
0.000 0.440 0.560
E10.2 With renal complications
0.000 0.460 0.540
E14.8 With unspecified complications
0.000 0.466 0.534
E14.7 With multiple complications
0.000 0.466 0.534
E14.6 With other specified complications
0.000 0.466 0.534
E14.5 With peripheral circulatory complications
0.000 0.466 0.534
E14.4 With neurological complications
0.000 0.466 0.534
E14.2 Withrenal complications
0.000 0.466 0.534
E14.1 With ketoacidosis
0.000 0.466 0.534
E14.0 With coma
0.000 0.466 0.534
E89.3 Postprocedural hypopituitarism
0.000 0.468 0.532
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.488 0.512
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.488 0.512
E70.3 Albinism
0.000 0.488 0.512
E70.2 Disorders of tyrosine metabolism
0.000 0.488 0.512
E70.1 Other hyperphenylalaninaemias
0.000 0.488 0.512
E70.0 Classical phenylketonuria
0.000 0.488 0.512
E71.3 Disorders of fatty-acid metabolism
0.000 0.488 0.512
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.488 0.512
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.488 0.512
E71.0 Maple-syrup-urine disease
0.000 0.488 0.512
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.488 0.512
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.488 0.512
E72.5 Disorders of glycine metabolism
0.000 0.488 0.512
E72.4 Disorders of ornithine metabolism
0.000 0.488 0.512
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.488 0.512
E72.2 Disorders of urea cycle metabolism
0.000 0.488 0.512
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.488 0.512
E72.0 Disorders of amino-acid transport
0.000 0.488 0.512
E75.6 Lipid storage disorder, unspecified
0.000 0.488 0.512
E75.5 Other lipid storage disorders
0.000 0.488 0.512
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.488 0.512
E75.3 Sphingolipidosis, unspecified
0.000 0.488 0.512
E75.2 Other sphingolipidosis
0.000 0.488 0.512
E75.1 Other gangliosidosis
0.000 0.488 0.512
E75.0 GM2 gangliosidosis
0.000 0.488 0.512
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.488 0.512
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.488 0.512
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.488 0.512
E76.2 Other mucopolysaccharidoses
0.000 0.488 0.512
E76.1 Mucopolysaccharidosis, type II
0.000 0.488 0.512
E76.0 Mucopolysaccharidosis, type I
0.000 0.488 0.512
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.488 0.512
E77.8 Other disorders of glycoprotein metabolism
0.000 0.488 0.512
E77.1 Defects in glycoprotein degradation
0.000 0.488 0.512
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.488 0.512
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.488 0.512
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.488 0.512
E79.1 Lesch-Nyhan syndrome
0.000 0.488 0.512
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.488 0.512
E84.9 Cystic fibrosis, unspecified
0.000 0.488 0.512
E84.8 Cystic fibrosis with other manifestations
0.000 0.488 0.512
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.488 0.512
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.488 0.512
E85.4 Organ-limited amyloidosis
0.000 0.491 0.509
E85.8 Other amyloidosis
0.000 0.495 0.505
E85.3 Secondary systemic amyloidosis
0.000 0.495 0.505
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.495 0.505
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.495 0.505
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.495 0.505
E46 Unspecified protein-energy malnutrition
0.000 0.495 0.505
E15 Nondiabetic hypoglycaemic coma
0.000 0.499 0.501
E85.9 Amyloidosis, unspecified
0.000 0.508 0.492
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.518 0.482
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.518 0.482
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.518 0.482
E74.2 Disorders of galactose metabolism
0.000 0.518 0.482
E74.1 Disorders of fructose metabolism
0.000 0.518 0.482
E74.0 Glycogen storage disease
0.000 0.518 0.482
E13.9 Without complications
0.000 0.536 0.464
K90.8 Other intestinal malabsorption
0.000 0.540 0.460
K90.3 Pancreatic steatorrhoea
0.000 0.540 0.460
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.540 0.460
K90.1 Tropical sprue
0.000 0.540 0.460
K90.9 Intestinal malabsorption, unspecified
0.000 0.542 0.457
E73.8 Other lactose intolerance
0.000 0.544 0.456
E73.1 Secondary lactase deficiency
0.000 0.544 0.456
E73.0 Congenital lactase deficiency
0.000 0.544 0.456
E50-E64 Other nutritional deficiencies
0.000 0.547 0.453
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.548 0.452
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.548 0.452
E16.4 Abnormal secretion of gastrin
0.000 0.548 0.452
E16.3 Increased secretion of glucagon
0.000 0.548 0.452
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.551 0.449
E45 Retarded development following protein-energy malnutrition
0.000 0.551 0.449
E43 Unspecified severe protein-energy malnutrition
0.000 0.551 0.449
E42 Marasmic kwashiorkor
0.000 0.551 0.449
E41 Nutritional marasmus
0.000 0.551 0.449
E40 Kwashiorkor
0.000 0.551 0.449
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.559 0.441
E80.5 Crigler-Najjar syndrome
0.000 0.559 0.441
E80.3 Defects of catalase and peroxydase
0.000 0.559 0.441
E80.2 Other porphyria
0.000 0.559 0.441
E80.1 Porphyria cutanea tarda
0.000 0.559 0.441
E80.0 Hereditary erythropoietic porphyria
0.000 0.559 0.441
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.560 0.440
K90-K93 Other diseases of the digestive system
0.000 0.566 0.434
E13.8 With unspecified complications
0.000 0.570 0.430
E13.7 With multiple complications
0.000 0.570 0.430
E13.6 With other specified complications
0.000 0.570 0.430
E13.5 With peripheral circulatory complications
0.000 0.570 0.430
E13.4 With neurological complications
0.000 0.570 0.430
E13.3 With ophthalmic complications
0.000 0.570 0.430
E13.2 With renal complications
0.000 0.570 0.430
E13.1 With ketoacidosis
0.000 0.570 0.430
E13.0 With coma
0.000 0.570 0.430
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.578 0.422
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.579 0.421
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.579 0.421
E80.4 Gilbert's syndrome
0.000 0.592 0.408
E16.1 Other hypoglycaemia
0.000 0.594 0.406
E12.9 Without complications
0.000 0.594 0.406
E12.8 With unspecified complications
0.000 0.594 0.406
E12.7 With multiple complications
0.000 0.594 0.406
E12.6 With other specified complications
0.000 0.594 0.406
E12.5 With peripheral circulatory complications
0.000 0.594 0.406
E12.4 With neurological complications
0.000 0.594 0.406
E12.3 With ophthalmic complications
0.000 0.594 0.406
E12.2 With renal complications
0.000 0.594 0.406
E12.1 With ketoacidosis
0.000 0.594 0.406
E12.0 With coma
0.000 0.594 0.406
E65-E68 Obesity and other hyperalimentation
0.000 0.597 0.403
E80.6 Other disorders of bilirubin metabolism
0.000 0.615 0.385
K91.4 Colostomy and enterostomy malfunction
0.000 0.621 0.379
E73.9 Lactose intolerance, unspecified
0.000 0.622 0.377
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.623 0.377
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.668 0.332
K91.3 Postoperative intestinal obstruction
0.000 0.674 0.326
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.675 0.325
E63 Other nutritional deficiencies
0.000 0.675 0.325
E56 Other vitamin deficiencies
0.000 0.675 0.325
E51 Thiamine deficiency
0.000 0.675 0.325
E50 Vitamin A deficiency
0.000 0.675 0.325
E60 Dietary zinc deficiency
0.000 0.675 0.325
E59 Dietary selenium deficiency
0.000 0.675 0.325
E58 Dietary calcium deficiency
0.000 0.675 0.325
E54 Ascorbic acid deficiency
0.000 0.675 0.325
E52 Niacin deficiency [pellagra]
0.000 0.675 0.325
E44.1 Mild protein-energy malnutrition
0.000 0.678 0.322
E44.0 Moderate protein-energy malnutrition
0.000 0.678 0.322
E61 Deficiency of other nutrient elements
0.000 0.680 0.320
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.689 0.311
E65 Localised adiposity
0.000 0.690 0.310
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.698 0.302
K91.5 Postcholecystectomy syndrome
0.000 0.698 0.302
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.698 0.302
K91.1 Postgastric surgery syndromes
0.000 0.698 0.302
E67 Other hyperalimentation
0.000 0.711 0.289
E68 Sequelae of hyperalimentation
0.000 0.711 0.289
E55 Vitamin D deficiency
0.000 0.717 0.283
E53 Deficiency of other B group vitamins
0.000 0.724 0.276
E50.9 Vitamin A deficiency, unspecified
0.000 0.767 0.233
E50.8 Other manifestations of vitamin A deficiency
0.000 0.767 0.233
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.767 0.233
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.767 0.233
E50.5 Vitamin A deficiency with night blindness
0.000 0.767 0.233
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.767 0.233
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.767 0.233
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.767 0.233
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.767 0.233
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.767 0.233
E51.9 Thiamine deficiency, unspecified
0.000 0.767 0.233
E51.8 Other manifestations of thiamine deficiency
0.000 0.767 0.233
E51.2 Wernicke's encephalopathy
0.000 0.767 0.233
E51.1 Beriberi
0.000 0.767 0.233
E56.9 Vitamin deficiency, unspecified
0.000 0.767 0.233
E56.8 Deficiency of other vitamins
0.000 0.767 0.233
E56.1 Deficiency of vitamin K
0.000 0.767 0.233
E56.0 Deficiency of vitamin E
0.000 0.767 0.233
E63.9 Nutritional deficiency, unspecified
0.000 0.767 0.233
E63.8 Other specified nutritional deficiencies
0.000 0.767 0.233
E63.1 Imbalance of constituents of food intake
0.000 0.767 0.233
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.767 0.233
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.767 0.233
E64.8 Sequelae of other nutritional deficiencies
0.000 0.767 0.233
E64.3 Sequelae of rickets
0.000 0.767 0.233
E64.2 Sequelae of vitamin C deficiency
0.000 0.767 0.233
E64.1 Sequelae of vitamin A deficiency
0.000 0.767 0.233
E64.0 Sequelae of protein-energy malnutrition
0.000 0.767 0.233
E61.9 Deficiency of nutrient element, unspecified
0.000 0.770 0.230
E61.8 Deficiency of other specified nutrient elements
0.000 0.770 0.230
E61.7 Deficiency of multiple nutrient elements
0.000 0.770 0.230
E61.6 Vanadium deficiency
0.000 0.770 0.230
E61.5 Molybdenum deficiency
0.000 0.770 0.230
E61.4 Chromium deficiency
0.000 0.770 0.230
E61.3 Manganese deficiency
0.000 0.770 0.230
E61.2 Magnesium deficiency
0.000 0.770 0.230
E61.0 Copper deficiency
0.000 0.770 0.230
E61.1 Iron deficiency
0.000 0.775 0.225
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.777 0.223
K93.1 Megacolon in Chagas' disease
0.000 0.777 0.223
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.777 0.223
E67.8 Other specified hyperalimentation
0.000 0.792 0.207
E67.3 Hypervitaminosis D
0.000 0.792 0.207
E67.2 Megavitamin-B6 syndrome
0.000 0.792 0.207
E67.1 Hypercarotenaemia
0.000 0.792 0.207
E67.0 Hypervitaminosis A
0.000 0.792 0.207
E55.0 Rickets, active
0.000 0.797 0.203
E53.9 Vitamin B deficiency, unspecified
0.000 0.802 0.198
E53.1 Pyridoxine deficiency
0.000 0.802 0.198
E53.0 Riboflavin deficiency
0.000 0.802 0.198
E20-E35 Disorders of other endocrine glands
0.001 0.815 0.184
E00-E07 Disorders of thyroid gland
0.000 0.823 0.176
E55.9 Vitamin D deficiency, unspecified
0.000 0.839 0.160
E11 Non-insulin-dependent diabetes mellitus
0.000 0.847 0.153
E53.8 Deficiency of other specified B group vitamins
0.000 0.851 0.149
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.853 0.147
E24 Cushing's syndrome
0.000 0.853 0.147
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.856 0.143
E29 Testicular dysfunction
0.000 0.857 0.142
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.867 0.132
E32 Diseases of thymus
0.001 0.867 0.132
E31 Polyglandular dysfunction
0.001 0.867 0.132
E30 Disorders of puberty, not elsewhere classified
0.001 0.867 0.132
E25 Adrenogenital disorders
0.001 0.867 0.132
E20 Hypoparathyroidism
0.001 0.867 0.132
E34 Other endocrine disorders
0.001 0.870 0.130
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.873 0.127
E00 Congenital iodine-deficiency syndrome
0.000 0.873 0.127
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.873 0.127
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.874 0.126
E26 Hyperaldosteronism
0.001 0.875 0.124
E11.6 With other specified complications
0.000 0.878 0.122
E05.9 Thyrotoxicosis, unspecified
0.000 0.880 0.120
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.880 0.120
E11.5 With peripheral circulatory complications
0.000 0.880 0.120
E24.9 Cushing's syndrome, unspecified
0.000 0.880 0.119
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.884 0.116
E29.1 Testicular hypofunction
0.000 0.887 0.112
E11.7 With multiple complications
0.000 0.890 0.110
E11.2 With renal complications
0.000 0.890 0.110
E28 Ovarian dysfunction
0.001 0.891 0.108
E21.3 Hyperparathyroidism, unspecified
0.000 0.892 0.108
E05.8 Other thyrotoxicosis
0.000 0.894 0.106
E05.5 Thyroid crisis or storm
0.000 0.894 0.106
E05.4 Thyrotoxicosis factitia
0.000 0.894 0.106
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.894 0.106
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.894 0.106
E24.8 Other Cushing's syndrome
0.000 0.894 0.105
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.894 0.105
E24.3 Ectopic ACTH syndrome
0.000 0.894 0.105
E24.2 Drug-induced Cushing's syndrome
0.000 0.894 0.105
E24.1 Nelson's syndrome
0.000 0.894 0.105
E24.0 Pituitary-dependent Cushing's disease
0.000 0.894 0.105
E11.8 With unspecified complications
0.000 0.896 0.103
E11.0 With coma
0.000 0.897 0.103
E29.9 Testicular dysfunction, unspecified
0.000 0.897 0.102
E29.8 Other testicular dysfunction
0.000 0.897 0.102
E29.0 Testicular hyperfunction
0.000 0.897 0.102
E34.9 Endocrine disorder, unspecified
0.000 0.899 0.101
E07 Other disorders of thyroid
0.000 0.901 0.098
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.902 0.098
E20.9 Hypoparathyroidism, unspecified
0.001 0.904 0.095
E20.8 Other hypoparathyroidism
0.001 0.904 0.095
E20.1 Pseudohypoparathyroidism
0.001 0.904 0.095
E20.0 Idiopathic hypoparathyroidism
0.001 0.904 0.095
E25.9 Adrenogenital disorder, unspecified
0.001 0.904 0.095
E25.8 Other adrenogenital disorders
0.001 0.904 0.095
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.904 0.095
E30.9 Disorder of puberty, unspecified
0.001 0.904 0.095
E30.8 Other disorders of puberty
0.001 0.904 0.095
E30.1 Precocious puberty
0.001 0.904 0.095
E30.0 Delayed puberty
0.001 0.904 0.095
E31.9 Polyglandular dysfunction, unspecified
0.001 0.904 0.095
E31.8 Other polyglandular dysfunction
0.001 0.904 0.095
E31.1 Polyglandular hyperfunction
0.001 0.904 0.095
E31.0 Autoimmune polyglandular failure
0.001 0.904 0.095
E32.9 Disease of thymus, unspecified
0.001 0.904 0.095
E32.8 Other diseases of thymus
0.001 0.904 0.095
E32.1 Abscess of thymus
0.001 0.904 0.095
E32.0 Persistent hyperplasia of thymus
0.001 0.904 0.095
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.904 0.095
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.904 0.095
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.904 0.095
E06 Thyroiditis
0.001 0.906 0.093
E34.5 Androgen resistance syndrome
0.001 0.906 0.093
E34.4 Constitutional tall stature
0.001 0.906 0.093
E34.3 Short stature, not elsewhere classified
0.001 0.906 0.093
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.906 0.093
E34.1 Other hypersecretion of intestinal hormones
0.001 0.906 0.093
E34.0 Carcinoid syndrome
0.001 0.906 0.093
E11.4 With neurological complications
0.000 0.908 0.092
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.909 0.091
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.909 0.091
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.909 0.091
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.909 0.091
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.909 0.091
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.909 0.091
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.909 0.091
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.909 0.091
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.909 0.090
E21.4 Other specified disorders of parathyroid gland
0.000 0.909 0.090
E21.2 Other hyperparathyroidism
0.000 0.909 0.090
E26.9 Hyperaldosteronism, unspecified
0.001 0.910 0.089
E26.8 Other hyperaldosteronism
0.001 0.910 0.089
E26.1 Secondary hyperaldosteronism
0.001 0.910 0.089
E78.8 Other disorders of lipoprotein metabolism
0.000 0.911 0.089
E27 Other disorders of adrenal gland
0.001 0.911 0.088
E78.4 Other hyperlipidaemia
0.000 0.913 0.087
E22 Hyperfunction of pituitary gland
0.001 0.913 0.086
E78.2 Mixed hyperlipidaemia
0.000 0.914 0.086
E11.3 With ophthalmic complications
0.000 0.916 0.084
E78.6 Lipoprotein deficiency
0.000 0.916 0.084
E78.3 Hyperchylomicronaemia
0.000 0.916 0.084
E26.0 Primary hyperaldosteronism
0.001 0.918 0.081
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.919 0.080
E34.8 Other specified endocrine disorders
0.001 0.920 0.080
E23 Hypofunction and other disorders of pituitary gland
0.001 0.921 0.079
E28.9 Ovarian dysfunction, unspecified
0.001 0.922 0.078
E28.8 Other ovarian dysfunction
0.001 0.922 0.078
E28.3 Primary ovarian failure
0.001 0.922 0.078
E28.1 Androgen excess
0.001 0.922 0.078
E28.0 Oestrogen excess
0.001 0.922 0.078
E78.1 Pure hyperglyceridaemia
0.000 0.924 0.076
E11.1 With ketoacidosis
0.000 0.926 0.074
E07.8 Other specified disorders of thyroid
0.000 0.929 0.070
E07.1 Dyshormogenetic goitre
0.000 0.929 0.070
E07.0 Hypersecretion of calcitonin
0.000 0.929 0.070
E06.9 Thyroiditis, unspecified
0.001 0.930 0.069
E03 Other hypothyroidism
0.000 0.932 0.068
E06.5 Other chronic thyroiditis
0.001 0.932 0.067
E06.4 Drug-induced thyroiditis
0.001 0.932 0.067
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.932 0.067
E06.1 Subacute thyroiditis
0.001 0.932 0.067
E06.0 Acute thyroiditis
0.001 0.932 0.067
E27.1 Primary adrenocortical insufficiency
0.000 0.934 0.065
E27.5 Adrenomedullary hyperfunction
0.001 0.936 0.063
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.936 0.063
E27.2 Addisonian crisis
0.001 0.936 0.063
E27.0 Other adrenocortical overactivity
0.001 0.936 0.063
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.938 0.062
E22.8 Other hyperfunction of pituitary gland
0.001 0.938 0.062
E21.0 Primary hyperparathyroidism
0.000 0.940 0.060
E27.8 Other specified disorders of adrenal gland
0.001 0.941 0.059
E66 Obesity
0.000 0.941 0.059
E22.0 Acromegaly and pituitary gigantism
0.001 0.941 0.058
E23.7 Disorder of pituitary gland, unspecified
0.001 0.943 0.056
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.943 0.056
E23.1 Drug-induced hypopituitarism
0.001 0.943 0.056
E27.4 Other and unspecified adrenocortical insufficiency
0.001 0.944 0.055
E28.2 Polycystic ovarian syndrome
0.001 0.946 0.053
E03.8 Other specified hypothyroidism
0.000 0.948 0.052
E22.1 Hyperprolactinaemia
0.001 0.949 0.050
E03.5 Myxoedema coma
0.000 0.951 0.049
E03.4 Atrophy of thyroid (acquired)
0.000 0.951 0.049
E03.3 Postinfectious hypothyroidism
0.000 0.951 0.049
E03.1 Congenital hypothyroidism without goitre
0.000 0.951 0.049
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.951 0.049
E23.6 Other disorders of pituitary gland
0.001 0.951 0.048
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.952 0.048
E23.2 Diabetes insipidus
0.001 0.955 0.044
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.955 0.044
E04 Other non-toxic goitre
0.000 0.955 0.044
K92 Other diseases of digestive system
0.000 0.956 0.044
E23.0 Hypopituitarism
0.001 0.957 0.043
E66.1 Drug-induced obesity
0.000 0.957 0.042
E07.9 Disorder of thyroid, unspecified
0.001 0.958 0.042
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.958 0.041
E27.9 Disorder of adrenal gland, unspecified
0.001 0.960 0.039
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.963 0.037
E66.0 Obesity due to excess calories
0.000 0.964 0.036
K92.8 Other specified diseases of digestive system
0.000 0.966 0.034
E04.8 Other specified non-toxic goitre
0.000 0.968 0.032
K92.9 Disease of digestive system, unspecified
0.000 0.968 0.032
E04.0 Non-toxic diffuse goitre
0.000 0.969 0.030
E06.3 Autoimmune thyroiditis
0.002 0.971 0.027
E04.9 Non-toxic goitre, unspecified
0.000 0.978 0.022
H40.2 Primary angle-closure glaucoma
0.022 0.978 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.979 0.020
E04.2 Non-toxic multinodular goitre
0.000 0.979 0.020
E66.8 Other obesity
0.000 0.985 0.015
E78.5 Hyperlipidaemia, unspecified
0.000 0.986 0.014
H53.9 Visual disturbance, unspecified
0.012 0.988 0.000
M06.9 Rheumatoid arthritis, unspecified
0.012 0.988 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.011 0.989 0.000
K92.0 Haematemesis
0.000 0.989 0.011
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.011 0.989 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.011 0.989 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.011 0.989 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.010 0.990 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.009 0.991 0.000
I42.0 Dilated cardiomyopathy
0.009 0.991 0.000
H40 Glaucoma
0.009 0.991 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.009 0.991 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.009 0.991 0.000
H40.8 Other glaucoma
0.008 0.992 0.000
H40.5 Glaucoma secondary to other eye disorders
0.008 0.992 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.008 0.992 0.000
E66.9 Obesity, unspecified
0.000 0.992 0.008
M06 Other rheumatoid arthritis
0.008 0.992 0.000
I42 Cardiomyopathy
0.008 0.992 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.008 0.992 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.007 0.993 0.000
H40.6 Glaucoma secondary to drugs
0.007 0.993 0.000
H40.4 Glaucoma secondary to eye inflammation
0.007 0.993 0.000
H40.3 Glaucoma secondary to eye trauma
0.007 0.993 0.000
H40.1 Primary open-angle glaucoma
0.007 0.993 0.000
I42.6 Alcoholic cardiomyopathy
0.006 0.993 0.000
M06.4 Inflammatory polyarthropathy
0.006 0.994 0.000
I42.2 Other hypertrophic cardiomyopathy
0.006 0.994 0.000
K92.1 Melaena
0.000 0.994 0.006
M06.0 Seronegative rheumatoid arthritis
0.006 0.994 0.000
M06.3 Rheumatoid nodule
0.006 0.994 0.000
I42.8 Other cardiomyopathies
0.006 0.994 0.000
I42.9 Cardiomyopathy, unspecified
0.006 0.994 0.000
M06.8 Other specified rheumatoid arthritis
0.006 0.994 0.000
M06.2 Rheumatoid bursitis
0.006 0.994 0.000
M06.1 Adult-onset Still's disease
0.006 0.994 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.006 0.994 0.000
I42.5 Other restrictive cardiomyopathy
0.006 0.994 0.000
I42.4 Endocardial fibroelastosis
0.006 0.994 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.006 0.994 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.005 0.995 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.005 0.995 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.005 0.995 0.000
N87.0 Mild cervical dysplasia
0.005 0.995 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.005 0.995 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.005 0.995 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.005 0.995 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.005 0.995 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.005 0.995 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.005 0.995 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.005 0.995 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.005 0.995 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.005 0.995 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.005 0.995 0.000
M06.34 Rheumatoid nodule (Hand)
0.005 0.995 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.005 0.995 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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