TreeWAS – Variant ID: rs7665090

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G35 Multiple sclerosis	0.086	0.914	0.000
R94.5 Abnormal results of liver function studies	0.040	0.960	0.000
R94.4 Abnormal results of kidney function studies	0.036	0.964	0.000
R94 Abnormal results of function studies	0.035	0.965	0.000
R41.3 Other amnesia	0.034	0.966	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.030	0.970	0.000
R90.0 Intracranial space-occupying lesion	0.029	0.971	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.029	0.971	0.000
L40.0 Psoriasis vulgaris	0.029	0.971	0.000
R94.2 Abnormal results of pulmonary function studies	0.028	0.972	0.000
D86.0 Sarcoidosis of lung	0.028	0.972	0.000
R94.6 Abnormal results of thyroid function studies	0.027	0.973	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.027	0.973	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.027	0.973	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.027	0.973	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.025	0.974	0.000
R41.0 Disorientation, unspecified	0.026	0.974	0.000
L40 Psoriasis	0.025	0.975	0.000
D86 Sarcoidosis	0.025	0.975	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.024	0.976	0.000
D23.1 Skin of eyelid, including canthus	0.000	0.976	0.024
L40.9 Psoriasis, unspecified	0.024	0.976	0.000
D60-D64 Aplastic and other anaemias	0.023	0.977	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.023	0.977	0.000
D86.9 Sarcoidosis, unspecified	0.023	0.977	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.022	0.978	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.022	0.978	0.000
D80-D89 Certain disorders involving the immune mechanism	0.022	0.978	0.000
D70 Agranulocytosis	0.022	0.978	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.021	0.979	0.000
L40.3 Pustulosis palmaris et plantaris	0.021	0.979	0.000
L40.5 Arthropathic psoriasis	0.021	0.979	0.000
D64 Other anaemias	0.021	0.979	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.021	0.979	0.000
R94.0 Abnormal results of function studies of central nervous system	0.020	0.979	0.000
D61 Other aplastic anaemias	0.021	0.979	0.000
D63.0 Anaemia in neoplastic disease	0.020	0.980	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.020	0.980	0.000
D55-D59 Haemolytic anaemias	0.019	0.981	0.000
D64.9 Anaemia, unspecified	0.019	0.981	0.000
R41.1 Anterograde amnesia	0.019	0.981	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.019	0.981	0.000
L40.1 Generalised pustular psoriasis	0.019	0.981	0.000
D59 Acquired haemolytic anaemia	0.019	0.981	0.000
L40.2 Acrodermatitis continua	0.018	0.981	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.018	0.981	0.000
D80 Immunodeficiency with predominantly antibody defects	0.018	0.982	0.000
D59.1 Other autoimmune haemolytic anaemias	0.018	0.982	0.000
D86.3 Sarcoidosis of skin	0.018	0.982	0.000
L40.4 Guttate psoriasis	0.018	0.982	0.000
L40.8 Other psoriasis	0.017	0.982	0.000
D61.9 Aplastic anaemia, unspecified	0.017	0.983	0.000
R94.7 Abnormal results of other endocrine function studies	0.017	0.983	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.017	0.983	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.017	0.983	0.000
D82 Immunodeficiency associated with other major defects	0.016	0.983	0.000
D61.0 Constitutional aplastic anaemia	0.016	0.984	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.016	0.984	0.000
D81 Combined immunodeficiencies	0.016	0.984	0.000
R41.2 Retrograde amnesia	0.016	0.984	0.000
D58 Other hereditary haemolytic anaemias	0.016	0.984	0.000
D61.1 Drug-induced aplastic anaemia	0.016	0.984	0.000
D64.0 Hereditary sideroblastic anaemia	0.015	0.984	0.000
D64.8 Other specified anaemias	0.015	0.985	0.000
D64.4 Congenital dyserythropoietic anaemia	0.015	0.985	0.000
D64.3 Other sideroblastic anaemias	0.015	0.985	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.015	0.985	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.015	0.985	0.000
D57 Sickle-cell disorders	0.015	0.985	0.000
D61.8 Other specified aplastic anaemias	0.015	0.985	0.000
D61.3 Idiopathic aplastic anaemia	0.015	0.985	0.000
D61.2 Aplastic anaemia due to other external agents	0.015	0.985	0.000
D86.1 Sarcoidosis of lymph nodes	0.015	0.985	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.015	0.985	0.000
Q44.6 Cystic disease of liver	0.015	0.985	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.014	0.986	0.000
D86.8 Sarcoidosis of other and combined sites	0.014	0.986	0.000
D84 Other immunodeficiencies	0.014	0.986	0.000
D74 Methaemoglobinaemia	0.014	0.986	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.014	0.986	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.014	0.986	0.000
D83 Common variable immunodeficiency	0.014	0.986	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.014	0.986	0.000
D55 Anaemia due to enzyme disorders	0.014	0.986	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.014	0.986	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.014	0.986	0.000
D62 Acute posthaemorrhagic anaemia	0.014	0.986	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.014	0.986	0.000
D59.8 Other acquired haemolytic anaemias	0.013	0.986	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.013	0.986	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.013	0.986	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.013	0.986	0.000
D59.3 Haemolytic-uraemic syndrome	0.013	0.986	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.013	0.986	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.013	0.987	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.013	0.987	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.013	0.987	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.013	0.987	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.013	0.987	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.013	0.987	0.000
D72 Other disorders of white blood cells	0.013	0.987	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.013	0.987	0.000
G36 Other acute disseminated demyelination	0.012	0.987	0.000
D82.1 Di George's syndrome	0.012	0.987	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.012	0.988	0.000
D60.8 Other acquired pure red cell aplasias	0.012	0.988	0.000
D60.1 Transient acquired pure red cell aplasia	0.012	0.988	0.000
D60.0 Chronic acquired pure red cell aplasia	0.012	0.988	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.012	0.988	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.012	0.988	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.012	0.988	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.012	0.988	0.000
D82.2 Immunodeficiency with short-limbed stature	0.012	0.988	0.000
D82.0 Wiskott-Aldrich syndrome	0.012	0.988	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.012	0.988	0.000
C85.1 B-cell lymphoma, unspecified	0.012	0.988	0.000
D58.2 Other haemoglobinopathies	0.012	0.988	0.000
D57.1 Sickle-cell anaemia without crisis	0.012	0.988	0.000
D73 Diseases of spleen	0.012	0.988	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.012	0.988	0.000
D81.9 Combined immunodeficiency, unspecified	0.011	0.988	0.000
D81.8 Other combined immunodeficiencies	0.011	0.988	0.000
D81.7 Major histocompatibility complex class II deficiency	0.011	0.988	0.000
D81.6 Major histocompatibility complex class I deficiency	0.011	0.988	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.011	0.988	0.000
D81.4 Nezelof's syndrome	0.011	0.988	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.011	0.988	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.011	0.988	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.011	0.988	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.011	0.988	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.011	0.988	0.000
D58.1 Hereditary elliptocytosis	0.011	0.988	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.011	0.989	0.000
M25.06 Haemarthrosis (Lower leg)	0.000	0.989	0.011
D57.8 Other sickle-cell disorders	0.011	0.989	0.000
D57.3 Sickle-cell trait	0.011	0.989	0.000
D57.2 Double heterozygous sickling disorders	0.011	0.989	0.000
D57.0 Sickle-cell anaemia with crisis	0.011	0.989	0.000
T78.3 Angioneurotic oedema	0.011	0.989	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.010	0.989	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.010	0.989	0.000
D74.9 Methaemoglobinaemia, unspecified	0.010	0.989	0.000
D74.8 Other methaemoglobinaemias	0.010	0.989	0.000
D74.0 Congenital methaemoglobinaemia	0.010	0.989	0.000
D83.8 Other common variable immunodeficiencies	0.010	0.989	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.010	0.989	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.010	0.989	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.010	0.989	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.010	0.990	0.000
D55.8 Other anaemias due to enzyme disorders	0.010	0.990	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.010	0.990	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.010	0.990	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.010	0.990	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.010	0.990	0.000
Q44.7 Other congenital malformations of liver	0.010	0.990	0.000
D56 Thalassaemia	0.010	0.990	0.000
D73.3 Abscess of spleen	0.010	0.990	0.000
D75 Other diseases of blood and blood-forming organs	0.010	0.990	0.000
D84.8 Other specified immunodeficiencies	0.010	0.990	0.000
D84.9 Immunodeficiency, unspecified	0.010	0.990	0.000
D84.1 Defects in the complement system	0.010	0.990	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.990	0.010
Q44.5 Other congenital malformations of bile ducts	0.010	0.990	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.009	0.990	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.009	0.990	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.009	0.990	0.000
D72.8 Other specified disorders of white blood cells	0.010	0.990	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.990	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.010	0.990	0.000
D72.9 Disorder of white blood cells, unspecified	0.009	0.990	0.000
D72.0 Genetic anomalies of leukocytes	0.009	0.990	0.000
D73.9 Disease of spleen, unspecified	0.009	0.991	0.000
G36.9 Acute disseminated demyelination, unspecified	0.009	0.991	0.000
G36.8 Other specified acute disseminated demyelination	0.009	0.991	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.009	0.991	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.991	0.009
D73.1 Hypersplenism	0.009	0.991	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.009	0.991	0.000
Q44.4 Choledochal cyst	0.009	0.991	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.009	0.991	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.009	0.991	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.009	0.991	0.000
Q44.2 Atresia of bile ducts	0.009	0.991	0.000
Q44.1 Other congenital malformations of gallbladder	0.009	0.991	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.009	0.991	0.000
D73.4 Cyst of spleen	0.009	0.991	0.000
D83.9 Common variable immunodeficiency, unspecified	0.009	0.991	0.000
Q61.3 Polycystic kidney, unspecified	0.009	0.991	0.000
L40-L45 Papulosquamous disorders	0.009	0.991	0.000
D73.2 Chronic congestive splenomegaly	0.009	0.991	0.000
D21.5 Connective and other soft tissue of pelvis	0.000	0.991	0.009
D89.9 Disorder involving the immune mechanism, unspecified	0.008	0.991	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.009	0.991	0.000
D76.3 Other histiocytosis syndromes	0.008	0.991	0.000
D50-D53 Nutritional anaemias	0.009	0.991	0.000
Q61 Cystic kidney disease	0.008	0.992	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.992	0.008
D89.3 Immune reconstitution syndrome	0.008	0.992	0.000
D58.0 Hereditary spherocytosis	0.008	0.992	0.000
D21.9 Connective and other soft tissue, unspecified	0.000	0.992	0.008
G36.0 Neuromyelitis optica [Devic]	0.008	0.992	0.000
U88 Agent resistant to multiple antibiotics	0.008	0.992	0.000
D73.5 Infarction of spleen	0.008	0.992	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
Q61.2 Polycystic kidney, adult type	0.008	0.992	0.000
T78 Adverse effects, not elsewhere classified	0.008	0.992	0.000
G37 Other demyelinating diseases of central nervous system	0.008	0.992	0.000
D56.9 Thalassaemia, unspecified	0.007	0.992	0.000
D56.8 Other thalassaemias	0.007	0.992	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.007	0.992	0.000
D56.2 Delta-beta thalassaemia	0.007	0.992	0.000
D56.0 Alpha thalassaemia	0.007	0.992	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.992	0.008
D72.1 Eosinophilia	0.008	0.992	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.008	0.992	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
Q61.0 Congenital single renal cyst	0.008	0.992	0.000
D89.1 Cryoglobulinaemia	0.007	0.993	0.000
D73.8 Other diseases of spleen	0.007	0.993	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
Q61.9 Cystic kidney disease, unspecified	0.007	0.993	0.000
D21.4 Connective and other soft tissue of abdomen	0.000	0.993	0.007
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.993	0.007
D89.0 Polyclonal hypergammaglobulinaemia	0.007	0.993	0.000
L41 Parapsoriasis	0.007	0.993	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.007	0.993	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.000	0.993	0.007
D21.3 Connective and other soft tissue of thorax	0.000	0.993	0.007
D75.1 Secondary polycythaemia	0.007	0.993	0.000
U89.8 Agent resistant to other single specified antibiotic	0.007	0.993	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.007	0.993	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.007	0.993	0.000
Q61.4 Renal dysplasia	0.007	0.993	0.000
T78.2 Anaphylactic shock, unspecified	0.007	0.993	0.000
D51 Vitamin B12 deficiency anaemia	0.007	0.993	0.000
C85.0 Lymphosarcoma	0.007	0.993	0.000
L44 Other papulosquamous disorders	0.006	0.993	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.006	0.993	0.000
D56.3 Thalassaemia trait	0.006	0.993	0.000
U89 Agent resistant to other and unspecified antibiotics	0.006	0.994	0.000
Q40 Other congenital malformations of upper alimentary tract	0.006	0.994	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.006	0.994	0.000
H92.1 Otorrhoea	0.000	0.994	0.006
Q61.8 Other cystic kidney diseases	0.006	0.994	0.000
Q61.1 Polycystic kidney, infantile type	0.006	0.994	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.006	0.994	0.000
T78.9 Adverse effect, unspecified	0.006	0.994	0.000
T78.8 Other adverse effects, not elsewhere classified	0.006	0.994	0.000
D75.2 Essential thrombocytosis	0.006	0.994	0.000
Q45 Other congenital malformations of digestive system	0.006	0.994	0.000
D75.0 Familial erythrocytosis	0.006	0.994	0.000
M80 Osteoporosis with pathological fracture	0.006	0.994	0.000
L43 Lichen planus	0.006	0.994	0.000
D53 Other nutritional anaemias	0.006	0.994	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.006	0.994	0.000
D56.1 Beta thalassaemia	0.005	0.994	0.001
G37.5 Concentric sclerosis [Balo]	0.006	0.994	0.000
G37.4 Subacute necrotising myelitis	0.006	0.994	0.000
G37.2 Central pontine myelinolysis	0.006	0.994	0.000
G37.1 Central demyelination of corpus callosum	0.006	0.994	0.000
G37.0 Diffuse sclerosis	0.006	0.994	0.000
L41.1 Pityriasis lichenoides chronica	0.006	0.994	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.006	0.994	0.000
D52 Folate deficiency anaemia	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
Q39 Congenital malformations of oesophagus	0.006	0.994	0.000
R25.1 Tremor, unspecified	0.006	0.994	0.000
R94.3 Abnormal results of cardiovascular function studies	0.005	0.994	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.005	0.994	0.000
L42 Pityriasis rosea	0.005	0.994	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.005	0.995	0.000
L41.9 Parapsoriasis, unspecified	0.005	0.995	0.000
L41.8 Other parapsoriasis	0.005	0.995	0.000
L41.5 Retiform parapsoriasis	0.005	0.995	0.000
L41.4 Large plaque parapsoriasis	0.005	0.995	0.000
L41.3 Small plaque parapsoriasis	0.005	0.995	0.000
L41.2 Lymphomatoid papulosis	0.005	0.995	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.005	0.995	0.000
M62.88 Other specified disorders of muscle (Other)	0.005	0.995	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.005	0.995	0.000
Q38.8 Other congenital malformations of pharynx	0.005	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.005	0.995	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.005	0.995	0.000
D51.2 Transcobalamin II deficiency	0.005	0.995	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.005	0.995	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.005	0.995	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q40.1 Congenital hiatus hernia	0.005	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.005	0.995	0.000
L44.9 Papulosquamous disorder, unspecified	0.005	0.995	0.000
L44.8 Other specified papulosquamous disorders	0.005	0.995	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.005	0.995	0.000
L44.3 Lichen ruber moniliformis	0.005	0.995	0.000
L44.2 Lichen striatus	0.005	0.995	0.000
L44.1 Lichen nitidus	0.005	0.995	0.000
L44.0 Pityriasis rubra pilaris	0.005	0.995	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.005	0.995	0.000
Q38.6 Other congenital malformations of mouth	0.005	0.995	0.000
Q45.8 Other specified congenital malformations of digestive system	0.005	0.995	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.005	0.995	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.005	0.995	0.000
L43.0 Hypertrophic lichen planus	0.005	0.995	0.000
Q39.4 Oesophageal web	0.005	0.995	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.005	0.995	0.000
U84 Resistance to other antimicrobial drugs	0.005	0.995	0.000
U83 Resistance to other antibiotics	0.005	0.995	0.000
U82 Resistance to betalactam antibiotics	0.005	0.995	0.000
U85 Resistance to antineoplastic drugs	0.005	0.995	0.000
F60.9 Personality disorder, unspecified	0.000	0.995	0.005
Q38.5 Congenital malformations of palate, not elsewhere classified	0.005	0.995	0.000
L43.8 Other lichen planus	0.005	0.995	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.005	0.995	0.000
Q38.3 Other congenital malformations of tongue	0.005	0.995	0.000
Q38.2 Macroglossia	0.005	0.995	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.005	0.995	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.005	0.995	0.000
B99 Other and unspecified infectious diseases	0.005	0.995	0.000
M25.0 Haemarthrosis	0.000	0.995	0.005
Q61.5 Medullary cystic kidney	0.004	0.995	0.000
U89.9 Agent resistant to unspecified antibiotic	0.005	0.995	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.995	0.000
Q45.2 Congenital pancreatic cyst	0.004	0.995	0.000
Q45.1 Annular pancreas	0.004	0.995	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.995	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.005	0.995	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.004	0.995	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.004	0.995	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.004	0.995	0.000
Q38.7 Pharyngeal pouch	0.005	0.995	0.000
L43.3 Subacute (active) lichen planus	0.004	0.995	0.000
L43.2 Lichenoid drug reaction	0.004	0.995	0.000
L43.1 Bullous lichen planus	0.004	0.995	0.000
Q38.1 Ankyloglossia	0.004	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.005	0.995	0.000
M81.4 Drug-induced osteoporosis	0.005	0.995	0.000
D53.8 Other specified nutritional anaemias	0.004	0.995	0.000
D53.2 Scorbutic anaemia	0.004	0.995	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.004	0.995	0.000
D53.0 Protein deficiency anaemia	0.004	0.995	0.000
R25 Abnormal involuntary movements	0.005	0.995	0.000
R25.3 Fasciculation	0.004	0.996	0.000
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
D52.8 Other folate deficiency anaemias	0.004	0.996	0.000
D52.1 Drug-induced folate deficiency anaemia	0.004	0.996	0.000
D52.0 Dietary folate deficiency anaemia	0.004	0.996	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.004	0.996	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.004	0.996	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.004	0.996	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.004	0.996	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.004	0.996	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.004	0.996	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.004	0.996	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.004	0.996	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.004	0.996	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.004	0.996	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.004	0.996	0.000
Q39.8 Other congenital malformations of oesophagus	0.004	0.996	0.000
Q39.5 Congenital dilatation of oesophagus	0.004	0.996	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.004	0.996	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.004	0.996	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.004	0.996	0.000
Q39.0 Atresia of oesophagus without fistula	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
M62.8 Other specified disorders of muscle	0.004	0.996	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.004	0.996	0.000
M80.8 Other osteoporosis with pathological fracture	0.004	0.996	0.000
M85.0 Fibrous dysplasia (monostotic)	0.004	0.996	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.004	0.996	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.996	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.996	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.996	0.004
D75.9 Disease of blood and blood-forming organs, unspecified	0.004	0.996	0.000
R84.5 Abnormal microbiological findings	0.000	0.996	0.004
D53.9 Nutritional anaemia, unspecified	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
Z89 Acquired absence of limb	0.000	0.996	0.004
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.996	0.004
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.004	0.996	0.000
Q39.6 Diverticulum of oesophagus	0.004	0.996	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.996	0.004
R27.0 Ataxia, unspecified	0.004	0.996	0.000
M85.4 Solitary bone cyst	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
D52.9 Folate deficiency anaemia, unspecified	0.004	0.996	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.996	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.004	0.996	0.000
U82.8 Resistance to other betalactam antibiotics	0.004	0.996	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.004	0.996	0.000
U82.1 Resistance to methicillin	0.004	0.996	0.000
U82.0 Resistance to penicillin	0.004	0.996	0.000
U83.9 Resistance to unspecified antibiotic	0.004	0.996	0.000
U83.8 Resistance to other single specified antibiotic	0.004	0.996	0.000
U83.7 Resistance to multiple antibiotics	0.004	0.996	0.000
U83.2 Resistance to quinolones	0.004	0.996	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.004	0.996	0.000
U83.0 Resistance to vancomycin	0.004	0.996	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.004	0.996	0.000
U84.8 Resistance to other specified antimicrobial drug	0.004	0.996	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.004	0.996	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.004	0.996	0.000
U84.2 Resistance to antiviral drug(s)	0.004	0.996	0.000
U84.1 Resistance to antifungal drug(s)	0.004	0.996	0.000
U84.0 Resistance to antiparasitic drug(s)	0.004	0.996	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
S20.2 Contusion of thorax	0.004	0.996	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.004	0.996	0.000
M35.0 Sicca syndrome [Sjogren]	0.004	0.996	0.000
M25.09 Haemarthrosis (Site unspecified)	0.000	0.996	0.003
M25.08 Haemarthrosis (Other)	0.000	0.996	0.003
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.996	0.003
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.996	0.003
M25.04 Haemarthrosis (Hand)	0.000	0.996	0.003
M25.03 Haemarthrosis (Forearm)	0.000	0.996	0.003
M25.02 Haemarthrosis (Upper arm)	0.000	0.996	0.003
M25.01 Haemarthrosis (Shoulder region)	0.000	0.996	0.003
M25.00 Haemarthrosis (Multiple sites)	0.000	0.996	0.003
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.003	0.996	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.003	0.996	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.003	0.996	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.003	0.996	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.003	0.996	0.000
M83 Adult osteomalacia	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.996	0.000
M85.2 Hyperostosis of skull	0.004	0.996	0.000
M62.84 Other specified disorders of muscle (Hand)	0.003	0.996	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.003	0.996	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.003	0.996	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.003	0.996	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.003	0.996	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.003	0.996	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.003	0.996	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.003	0.996	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.003	0.996	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.003	0.996	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.003	0.996	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.003	0.996	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.003	0.996	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.003	0.996	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.003	0.996	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.003	0.996	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.003	0.996	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.003	0.996	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.003	0.996	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.003	0.996	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.003	0.996	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.003	0.996	0.000
D69.9 Haemorrhagic condition, unspecified	0.004	0.996	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.996	0.000
M62 Other disorders of muscle	0.004	0.996	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.996	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.996	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.996	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.996	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.996	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.996	0.000
Q43 Other congenital malformations of intestine	0.003	0.996	0.000
M81.8 Other osteoporosis	0.003	0.996	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.996	0.004
R25.0 Abnormal head movements	0.003	0.996	0.000
N99.5 Malfunction of external stoma of urinary tract	0.003	0.996	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.996	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.997	0.003
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.997	0.003
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.003	0.997	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.997	0.003
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations