TreeWAS – Variant ID: rs7665939

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.786	0.214	0.000
C79 Secondary malignant neoplasm of other sites	0.585	0.415	0.000
C79.2 Secondary malignant neoplasm of skin	0.541	0.459	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.507	0.493	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.494	0.506	0.000
C79.6 Secondary malignant neoplasm of ovary	0.474	0.526	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.398	0.602	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.387	0.613	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.382	0.618	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.296	0.704	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.236	0.764	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.055	0.945	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.040	0.959	0.000
C80 Malignant neoplasm without specification of site	0.040	0.960	0.000
C80.9 Malignant neoplasm, unspecified	0.031	0.969	0.000
C76.3 Pelvis	0.030	0.970	0.000
C76.0 Head, face and neck	0.030	0.970	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.029	0.971	0.000
C76.7 Other ill-defined sites	0.029	0.971	0.000
C76.5 Lower limb	0.029	0.971	0.000
C76.4 Upper limb	0.029	0.971	0.000
C76.2 Abdomen	0.029	0.971	0.000
C76.1 Thorax	0.029	0.971	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.026	0.974	0.000
H69.9 Eustachian tube disorder, unspecified	0.021	0.979	0.000
H69 Other disorders of Eustachian tube	0.020	0.980	0.000
H66 Suppurative and unspecified otitis media	0.019	0.980	0.000
H65-H75 Diseases of middle ear and mastoid	0.019	0.981	0.000
H72 Perforation of tympanic membrane	0.019	0.981	0.000
H66.9 Otitis media, unspecified	0.019	0.981	0.000
H72.8 Other perforations of tympanic membrane	0.018	0.982	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.017	0.983	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.017	0.983	0.000
C77.4 Inguinal and lower limb lymph nodes	0.016	0.984	0.000
H66.3 Other chronic suppurative otitis media	0.016	0.984	0.000
H69.8 Other specified disorders of Eustachian tube	0.015	0.985	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.015	0.985	0.000
H74 Other disorders of middle ear and mastoid	0.015	0.985	0.000
H70 Mastoiditis and related conditions	0.015	0.985	0.000
H69.0 Patulous Eustachian tube	0.014	0.985	0.000
H66.4 Suppurative otitis media, unspecified	0.014	0.985	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.014	0.986	0.000
H66.0 Acute suppurative otitis media	0.014	0.986	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.014	0.986	0.000
H68 Eustachian salpingitis and obstruction	0.014	0.986	0.000
H67 Otitis media in diseases classified elsewhere	0.014	0.986	0.000
H72.2 Other marginal perforations of tympanic membrane	0.014	0.986	0.000
H72.1 Attic perforation of tympanic membrane	0.014	0.986	0.000
H72.0 Central perforation of tympanic membrane	0.013	0.987	0.000
C77.1 Intrathoracic lymph nodes	0.013	0.987	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.013	0.987	0.000
H73 Other disorders of tympanic membrane	0.012	0.988	0.000
L89.1 Stage II decubitus ulcer	0.012	0.988	0.000
H65 Nonsuppurative otitis media	0.012	0.988	0.000
C77.5 Intrapelvic lymph nodes	0.012	0.988	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.012	0.988	0.000
H70.9 Mastoiditis, unspecified	0.012	0.988	0.000
H74.4 Polyp of middle ear	0.011	0.988	0.000
C77.3 Axillary and upper limb lymph nodes	0.011	0.989	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.011	0.989	0.000
H74.1 Adhesive middle ear disease	0.011	0.989	0.000
H70.8 Other mastoiditis and related conditions	0.011	0.989	0.000
H70.2 Petrositis	0.011	0.989	0.000
H70.1 Chronic mastoiditis	0.011	0.989	0.000
H70.0 Acute mastoiditis	0.011	0.989	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.011	0.989	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.011	0.989	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.989	0.011
H74.8 Other specified disorders of middle ear and mastoid	0.011	0.989	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.010	0.990	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.010	0.990	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.010	0.990	0.000
H68.1 Obstruction of Eustachian tube	0.010	0.990	0.000
H68.0 Eustachian salpingitis	0.010	0.990	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.010	0.990	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
H65.2 Chronic serous otitis media	0.010	0.990	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.010	0.990	0.000
H74.0 Tympanosclerosis	0.010	0.990	0.000
C77.0 Lymph nodes of head, face and neck	0.009	0.991	0.000
H71 Cholesteatoma of middle ear	0.009	0.991	0.000
H73.1 Chronic myringitis	0.009	0.991	0.000
H73.0 Acute myringitis	0.009	0.991	0.000
H65.1 Other acute nonsuppurative otitis media	0.009	0.991	0.000
H65.0 Acute serous otitis media	0.009	0.991	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.009	0.991	0.000
Z92.3 Personal history of irradiation	0.009	0.991	0.000
C77.8 Lymph nodes of multiple regions	0.008	0.991	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.009	0.991	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.008	0.992	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.008	0.992	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.007	0.993	0.000
Z92 Personal history of medical treatment	0.007	0.993	0.000
G20 Parkinson's disease	0.007	0.993	0.000
C77.9 Lymph node, unspecified	0.007	0.993	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.007	0.993	0.000
H65.4 Other chronic nonsuppurative otitis media	0.007	0.993	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.993	0.007
G12.2 Motor neuron disease	0.007	0.993	0.000
C78.0 Secondary malignant neoplasm of lung	0.006	0.994	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.006	0.994	0.000
Z92.0 Personal history of contraception	0.006	0.994	0.000
D12.2 Ascending colon	0.000	0.994	0.006
Z92.8 Personal history of other medical treatment	0.006	0.994	0.000
Z92.9 Personal history of medical treatment, unspecified	0.005	0.994	0.000
Z92.5 Personal history of rehabilitation measures	0.005	0.994	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.994	0.000
L89 Decubitus ulcer	0.005	0.994	0.000
G12 Spinal muscular atrophy and related syndromes	0.005	0.995	0.000
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
G47.9 Sleep disorder, unspecified	0.005	0.995	0.000
N95.2 Postmenopausal atrophic vaginitis	0.005	0.995	0.000
L89.2 Stage III decubitus ulcer	0.005	0.995	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.005	0.995	0.000
L89.3 Stage IV decubitus ulcer	0.004	0.995	0.000
Z53.9 Procedure not carried out, unspecified reason	0.004	0.996	0.000
G12.9 Spinal muscular atrophy, unspecified	0.004	0.996	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.004	0.996	0.000
G12.1 Other inherited spinal muscular atrophy	0.004	0.996	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.004	0.996	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.004	0.996	0.000
G20-G26 Extrapyramidal and movement disorders	0.004	0.996	0.000
G11 Hereditary ataxia	0.004	0.996	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.004	0.996	0.000
G80 Infantile cerebral palsy	0.004	0.996	0.000
Z22.3 Carrier of other specified bacterial diseases	0.004	0.996	0.000
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
G83 Other paralytic syndromes	0.004	0.996	0.000
C78.2 Secondary malignant neoplasm of pleura	0.004	0.996	0.000
G83.1 Monoplegia of lower limb	0.004	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.004	0.996	0.000
G11.9 Hereditary ataxia, unspecified	0.004	0.996	0.000
C77.2 Intra-abdominal lymph nodes	0.004	0.996	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.003	0.996	0.000
G14 Postpolio syndrome	0.003	0.996	0.000
G10 Huntington's disease	0.003	0.996	0.000
I51.8 Other ill-defined heart diseases	0.000	0.996	0.004
O80.9 Single spontaneous delivery, unspecified	0.000	0.996	0.004
G80.9 Infantile cerebral palsy, unspecified	0.003	0.996	0.000
C78.7 Secondary malignant neoplasm of liver	0.004	0.996	0.000
Chapter VI Diseases of the nervous system	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.003	0.997	0.000
G93 Other disorders of brain	0.003	0.997	0.000
G90-G99 Other disorders of the nervous system	0.003	0.997	0.000
G70-G73 Diseases of myoneural junction and muscle	0.003	0.997	0.000
G80.1 Spastic diplegia	0.003	0.997	0.000
G93.4 Encephalopathy, unspecified	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
G71 Primary disorders of muscles	0.003	0.997	0.000
G11.4 Hereditary spastic paraplegia	0.003	0.997	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.003	0.997	0.000
G23 Other degenerative diseases of basal ganglia	0.003	0.997	0.000
G21 Secondary Parkinsonism	0.003	0.997	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.003	0.997	0.000
G22 Parkinsonism in diseases classified elsewhere	0.003	0.997	0.000
G11.8 Other hereditary ataxias	0.003	0.997	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.003	0.997	0.000
G11.2 Late-onset cerebellar ataxia	0.003	0.997	0.000
G11.1 Early-onset cerebellar ataxia	0.003	0.997	0.000
G11.0 Congenital nonprogressive ataxia	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.003	0.997	0.000
G83.9 Paralytic syndrome, unspecified	0.003	0.997	0.000
G93.8 Other specified disorders of brain	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.003	0.997	0.000
G80.8 Other infantile cerebral palsy	0.003	0.997	0.000
G80.4 Ataxic cerebral palsy	0.003	0.997	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.997	0.000
G80.2 Infantile hemiplegia	0.003	0.997	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.003	0.997	0.000
N64.9 Disorder of breast, unspecified	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.003	0.997	0.000
G83.5 Locked-in syndrome	0.003	0.997	0.000
G83.3 Monoplegia, unspecified	0.003	0.997	0.000
G83.0 Diplegia of upper limbs	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.003	0.997	0.000
G72 Other myopathies	0.003	0.997	0.000
G47 Sleep disorders	0.003	0.997	0.000
G93.6 Cerebral oedema	0.003	0.997	0.000
G83.8 Other specified paralytic syndromes	0.003	0.997	0.000
N64.8 Other specified disorders of breast	0.000	0.997	0.003
N64 Other disorders of breast	0.000	0.997	0.003
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.003	0.997	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.003	0.997	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.003	0.997	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.003	0.997	0.000
G96 Other disorders of central nervous system	0.003	0.997	0.000
G91 Hydrocephalus	0.003	0.997	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.003	0.997	0.000
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
N64.1 Fat necrosis of breast	0.000	0.997	0.003
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.997	0.003
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.003	0.997	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.003	0.997	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.002	0.997	0.000
G82.4 Spastic tetraplegia	0.003	0.997	0.000
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
G82.0 Flaccid paraplegia	0.003	0.997	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.003	0.997	0.000
G95 Other diseases of spinal cord	0.003	0.997	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.003	0.997	0.000
G92 Toxic encephalopathy	0.003	0.997	0.000
G93.7 Reye's syndrome	0.003	0.997	0.000
K25 Gastric ulcer	0.000	0.997	0.003
Y40 Systemic antibiotics	0.003	0.997	0.000
N64.5 Other signs and symptoms in breast	0.000	0.997	0.003
I31.9 Disease of pericardium, unspecified	0.000	0.997	0.003
G24 Dystonia	0.002	0.997	0.000
G71.9 Primary disorder of muscle, unspecified	0.002	0.997	0.000
G71.8 Other primary disorders of muscles	0.002	0.997	0.000
G71.2 Congenital myopathies	0.002	0.997	0.000
G71.1 Myotonic disorders	0.002	0.997	0.000
G71.0 Muscular dystrophy	0.002	0.997	0.000
G40-G47 Episodic and paroxysmal disorders	0.003	0.997	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.003	0.997	0.000
G21.9 Secondary Parkinsonism, unspecified	0.002	0.997	0.000
G21.8 Other secondary Parkinsonism	0.002	0.997	0.000
G21.4 Vascular parkinsonism	0.002	0.997	0.000
G21.3 Postencephalitic Parkinsonism	0.002	0.997	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.002	0.997	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.002	0.997	0.000
G21.0 Malignant neuroleptic syndrome	0.002	0.997	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.002	0.997	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.997	0.000
G23.3 Multiple system atrophy, cerebellar type	0.002	0.997	0.000
G23.2 Striatonigral degeneration	0.002	0.997	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.002	0.997	0.000
G23.0 Hallervorden-Spatz disease	0.002	0.997	0.000
G93.5 Compression of brain	0.002	0.997	0.000
G70 Myasthenia gravis and other myoneural disorders	0.002	0.997	0.000
G90 Disorders of autonomic nervous system	0.002	0.997	0.000
G47.4 Narcolepsy and cataplexy	0.002	0.997	0.000
G72.0 Drug-induced myopathy	0.002	0.997	0.000
G83.2 Monoplegia of upper limb	0.002	0.997	0.000
G44 Other headache syndromes	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.002	0.997	0.000
G72.9 Myopathy, unspecified	0.002	0.997	0.000
G93.3 Postviral fatigue syndrome	0.002	0.997	0.000
Y40.3 Macrolides	0.002	0.997	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.997	0.000
O20.0 Threatened abortion	0.000	0.997	0.002
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.002	0.998	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.002	0.998	0.000
Z71.8 Other specified counselling	0.002	0.998	0.000
G91.0 Communicating hydrocephalus	0.002	0.998	0.000
Z22 Carrier of infectious disease	0.002	0.998	0.000
G72.8 Other specified myopathies	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.002	0.998	0.000
G72.3 Periodic paralysis	0.002	0.998	0.000
G72.2 Myopathy due to other toxic agents	0.002	0.998	0.000
G72.1 Alcoholic myopathy	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.002	0.998	0.000
G91.1 Obstructive hydrocephalus	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
G90.3 Multisystem degeneration	0.002	0.998	0.000
G93.0 Cerebral cysts	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
N64.3 Galactorrhoea not associated with childbirth	0.000	0.998	0.002
N64.2 Atrophy of breast	0.000	0.998	0.002
N64.0 Fissure and fistula of nipple	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.002	0.998	0.000
G95.0 Syringomyelia and syringobulbia	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
G44.2 Tension-type headache	0.002	0.998	0.000
G91.8 Other hydrocephalus	0.002	0.998	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.002	0.998	0.000
G44.8 Other specified headache syndromes	0.002	0.998	0.000
G90.2 Horner's syndrome	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.002	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
G96.0 Cerebrospinal fluid leak	0.002	0.998	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
G81 Hemiplegia	0.002	0.998	0.000
K25.0 Acute with haemorrhage	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
G73.7 Myopathy other diseases classified elsewhere	0.002	0.998	0.000
G73.6 Myopathy in metabolic diseases	0.002	0.998	0.000
G73.5 Myopathy in endocrine diseases	0.002	0.998	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.002	0.998	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.002	0.998	0.000
G73.1 Eaton-Lambert syndrome	0.002	0.998	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.002	0.998	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.002	0.998	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.002	0.998	0.000
G94.1 Hydrocephalus in neoplastic disease	0.002	0.998	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
K25.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
K25.5 Chronic or unspecified with perforation	0.000	0.998	0.002
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.998	0.002
K25.2 Acute with both haemorrhage and perforation	0.000	0.998	0.002
K25.1 Acute with perforation	0.000	0.998	0.002
R01.1 Cardiac murmur, unspecified	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.998	0.000
G24.3 Spasmodic torticollis	0.002	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.998	0.000
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
G24.0 Drug-induced dystonia	0.002	0.998	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.002	0.998	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.002	0.998	0.000
G70.2 Congenital and developmental myasthenia	0.002	0.998	0.000
G70.1 Toxic myoneural disorders	0.002	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
G90.4 Autonomic dysreflexia	0.002	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
N64.4 Mastodynia	0.000	0.998	0.002
G06 Intracranial and intraspinal abscess and granuloma	0.002	0.998	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.002	0.998	0.000
I22 Subsequent myocardial infarction	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.002	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
G44.3 Chronic posttraumatic headache	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
G30-G32 Other degenerative diseases of the nervous system	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
G47.8 Other sleep disorders	0.002	0.998	0.000
Z22.9 Carrier of infectious disease, unspecified	0.002	0.998	0.000
Z22.8 Carrier of other infectious diseases	0.002	0.998	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.002	0.998	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
Z22.2 Carrier of diphtheria	0.002	0.998	0.000
Z22.0 Carrier of typhoid	0.002	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.002	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
D50.8 Other iron deficiency anaemias	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
G41 Status epilepticus	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
D11.0 Parotid gland	0.000	0.998	0.002
J39.2 Other diseases of pharynx	0.000	0.998	0.002
N95.8 Other specified menopausal and perimenopausal disorders	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.002	0.998	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
G61.1 Serum neuropathy	0.002	0.998	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.002	0.998	0.000
G40 Epilepsy	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.002	0.998	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G02.1 Meningitis in mycoses	0.002	0.998	0.000
M16.1 Other primary coxarthrosis	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
G64 Other disorders of peripheral nervous system	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.002	0.998	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
D35.2 Pituitary gland	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.002	0.998	0.000
G04.1 Tropical spastic paraplegia	0.002	0.998	0.000
G04.0 Acute disseminated encephalitis	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.002	0.998	0.000
G06.2 Extradural and subdural abscess, unspecified	0.002	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.002	0.998	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.002	0.998	0.000
G46.6 Pure sensory lacunar syndrome	0.002	0.998	0.000
G46.5 Pure motor lacunar syndrome	0.002	0.998	0.000
G46.4 Cerebellar stroke syndrome	0.002	0.998	0.000
G46.3 Brain stem stroke syndrome	0.002	0.998	0.000
G46.2 Posterior cerebral artery syndrome	0.002	0.998	0.000
G46.1 Anterior cerebral artery syndrome	0.002	0.998	0.000
G46.0 Middle cerebral artery syndrome	0.002	0.998	0.000
N95 Menopausal and other perimenopausal disorders	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
G46.7 Other lacunar syndromes	0.002	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
G06.0 Intracranial abscess and granuloma	0.002	0.998	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.001	0.998	0.000
S22.3 Fracture of rib	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Z22.5 Carrier of viral hepatitis	0.002	0.998	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
G03.8 Meningitis due to other specified causes	0.001	0.998	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.001	0.998	0.000
G03.1 Chronic meningitis	0.001	0.998	0.000
G03.0 Nonpyogenic meningitis	0.001	0.998	0.000
G41.8 Other status epilepticus	0.001	0.998	0.000
G41.2 Complex partial status epilepticus	0.001	0.998	0.000
G41.1 Petit mal status epilepticus	0.001	0.998	0.000
G41.0 Grand mal status epilepticus	0.001	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.998	0.002
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.001	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.998	0.002
R26.3 Immobility	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
G00.8 Other bacterial meningitis	0.001	0.998	0.000
G00.3 Staphylococcal meningitis	0.001	0.998	0.000
G00.2 Streptococcal meningitis	0.001	0.998	0.000
G00.0 Haemophilus meningitis	0.001	0.998	0.000
G40.8 Other epilepsy	0.002	0.998	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.998	0.000
E16.3 Increased secretion of glucagon	0.001	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.998	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.001	0.998	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.001	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations