TreeWAS – Variant ID: rs766903

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13.3 Other and unspecified hydronephrosis	0.264	0.736	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.260	0.740	0.000
N13 Obstructive and reflux uropathy	0.255	0.745	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.220	0.780	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.211	0.789	0.000
N13.4 Hydroureter	0.189	0.811	0.000
N13.8 Other obstructive and reflux uropathy	0.162	0.838	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.161	0.839	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.147	0.853	0.000
N13.6 Pyonephrosis	0.134	0.866	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.128	0.872	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.896	0.104
Y45.0 Opioids and related analgesics	0.000	0.897	0.103
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.897	0.103
Y52 Agents primarily affecting the cardiovascular system	0.000	0.905	0.095
N10-N16 Renal tubulo-interstitial diseases	0.093	0.907	0.000
Y45.2 Propionic acid derivatives	0.000	0.907	0.093
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.907	0.093
Y57 Other and unspecified drugs and medicaments	0.000	0.909	0.091
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.909	0.091
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.912	0.088
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.914	0.086
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.915	0.085
Y45.5 4-Aminophenol derivatives	0.000	0.917	0.083
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.917	0.083
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.918	0.082
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.918	0.082
Y54.3 Benzothiadiazine derivatives	0.000	0.919	0.081
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.921	0.078
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.922	0.078
Y48 Anaesthetics and therapeutic gases	0.000	0.923	0.077
N11 Chronic tubulo-interstitial nephritis	0.077	0.923	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.923	0.076
Y54.5 Other diuretics	0.000	0.923	0.076
Y49.2 Other and unspecified antidepressants	0.000	0.923	0.076
Y57.8 Other drugs and medicaments	0.000	0.924	0.076
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.924	0.076
Y45.4 Antirheumatics	0.000	0.925	0.074
Y49.5 Other antipsychotics and neuroleptics	0.000	0.926	0.074
Y59 Other and unspecified vaccines and biological substances	0.000	0.926	0.074
Y58 Bacterial vaccines	0.000	0.926	0.074
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.926	0.074
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.926	0.074
Y57.5 X-ray contrast media	0.000	0.927	0.073
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.927	0.073
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.928	0.072
Y54.4 Loop [high-ceiling] diuretics	0.000	0.928	0.072
Y40 Systemic antibiotics	0.000	0.928	0.072
Y57.9 Drug or medicament, unspecified	0.000	0.929	0.071
N15 Other renal tubulo-interstitial diseases	0.070	0.930	0.000
Y52.1 Calcium-channel blockers	0.000	0.930	0.070
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.931	0.069
Y53.4 Other laxatives	0.000	0.931	0.069
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.932	0.068
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.932	0.068
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.932	0.068
Y52.7 Peripheral vasodilators	0.000	0.932	0.068
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.932	0.068
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.932	0.068
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.067	0.933	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.067	0.933	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.933	0.067
Y54.9 Mineral salts, not elsewhere classified	0.000	0.933	0.067
Y54.8 Agents affecting uric acid metabolism	0.000	0.933	0.067
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.933	0.067
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.933	0.067
Y54.0 Mineralocorticoids	0.000	0.933	0.067
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.933	0.067
Y57.6 Other diagnostic agents	0.000	0.933	0.067
Y57.7 Vitamins, not elsewhere classified	0.000	0.934	0.066
Y57.4 Pharmaceutical excipients	0.000	0.934	0.066
Y57.3 Alcohol deterrents	0.000	0.934	0.066
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.934	0.066
Y57.1 Lipotropic drugs	0.000	0.934	0.066
Y57.0 Appetite depressants [anorectics]	0.000	0.934	0.066
Y49.9 Psychotropic drug, unspecified	0.000	0.935	0.065
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.935	0.065
Y49.7 Psychostimulants with abuse potential	0.000	0.935	0.065
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.935	0.065
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.935	0.065
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.935	0.065
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.935	0.065
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.935	0.065
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.935	0.065
Y44 Agents primarily affecting blood constituents	0.000	0.935	0.064
Y42.9 Other and unspecified hormone antagonists	0.000	0.936	0.063
Y42.4 Oral contraceptives	0.000	0.936	0.063
Y42.2 Antithyroid drugs	0.000	0.936	0.063
Y42.1 Thyroid hormones and substitutes	0.000	0.936	0.063
Y41.0 Sulphonamides	0.000	0.938	0.062
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.938	0.062
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.938	0.062
Y53.7 Emetics	0.000	0.938	0.062
Y53.6 Antidiarrhoeal drugs	0.000	0.938	0.062
Y53.5 Digestants	0.000	0.938	0.062
Y53.3 Saline and osmotic laxatives	0.000	0.938	0.062
Y53.2 Stimulant laxatives	0.000	0.938	0.062
Y53.0 Histamine H2-receptor antagonists	0.000	0.938	0.062
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.061	0.939	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.939	0.061
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.061	0.939	0.000
Y47.1 Benzodiazepines	0.000	0.940	0.060
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.940	0.060
Y40.8 Other systemic antibiotics	0.000	0.940	0.060
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.940	0.060
Y41.4 Anthelminthics	0.000	0.940	0.060
Y41.3 Other antiprotozoal drugs	0.000	0.940	0.060
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.940	0.060
Y41.1 Antimycobacterial drugs	0.000	0.940	0.060
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.940	0.060
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.059	0.941	0.000
Y48.3 Local anaesthetics	0.000	0.942	0.058
Y41.5 Antiviral drugs	0.000	0.942	0.058
Y45.1 Salicylates	0.000	0.942	0.058
Y54.7 Agents affecting calcification	0.000	0.943	0.057
Y40.0 Penicillins	0.000	0.943	0.057
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.944	0.056
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.944	0.056
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.944	0.056
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.944	0.056
Y47.4 Bromine compounds	0.000	0.944	0.056
Y47.3 Paraldehyde	0.000	0.944	0.056
Y47.2 Chloral derivatives	0.000	0.944	0.056
Y47.0 Barbiturates, not elsewhere classified	0.000	0.944	0.056
Y48.4 Anaesthetic, unspecified	0.000	0.944	0.056
Y48.5 Therapeutic gases	0.000	0.944	0.055
Y48.1 Parenteral anaesthetics	0.000	0.944	0.055
Y48.0 Inhaled anaesthetics	0.000	0.944	0.055
N11.8 Other chronic tubulo-interstitial nephritis	0.055	0.945	0.000
N11.1 Chronic obstructive pyelonephritis	0.055	0.945	0.000
Y40.3 Macrolides	0.000	0.945	0.055
Y48.2 Other and unspecified general anaesthetics	0.000	0.945	0.055
Y43 Primarily systemic agents	0.000	0.945	0.055
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.945	0.054
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.945	0.054
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.945	0.054
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.945	0.054
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.945	0.054
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.945	0.054
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.945	0.054
Y51.0 Anticholinesterase agents	0.000	0.945	0.054
N15.1 Renal and perinephric abscess	0.053	0.947	0.000
Y50.9 Central nervous system stimulant, unspecified	0.000	0.947	0.053
Y50.8 Other central nervous system stimulants	0.000	0.947	0.053
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.947	0.053
Y50.1 Opioid receptor antagonists	0.000	0.947	0.053
Y50.0 Analeptics	0.000	0.947	0.053
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.947	0.053
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.947	0.053
Y55.5 Anticommon cold drugs	0.000	0.947	0.053
Y55.4 Expectorants	0.000	0.947	0.053
Y55.3 Antitussives	0.000	0.947	0.053
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.947	0.053
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.947	0.053
Y55.0 Oxytocic drugs	0.000	0.947	0.053
Y58.9 Other and unspecified bacterial vaccines	0.000	0.947	0.053
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.947	0.053
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.947	0.053
Y58.5 Diphtheria vaccine	0.000	0.947	0.053
Y58.4 Tetanus vaccine	0.000	0.947	0.053
Y58.3 Plague vaccine	0.000	0.947	0.053
Y58.2 Cholera vaccine	0.000	0.947	0.053
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.947	0.053
Y58.0 BCG vaccine	0.000	0.947	0.053
Y59.9 Vaccine or biological substance, unspecified	0.000	0.947	0.053
Y59.8 Other specified vaccines and biological substances	0.000	0.947	0.053
Y59.3 Immunoglobulin	0.000	0.947	0.053
Y59.2 Protozoal vaccines	0.000	0.947	0.053
Y59.1 Rickettsial vaccines	0.000	0.947	0.053
Y59.0 Viral vaccines	0.000	0.947	0.053
Y40.6 Rifamycins	0.000	0.948	0.051
Y40.5 Aminoglycosides	0.000	0.948	0.051
Y40.4 Tetracyclines	0.000	0.948	0.051
Y40.2 Chloramphenicol group	0.000	0.948	0.051
N15.9 Renal tubulo-interstitial disease, unspecified	0.050	0.949	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.050	0.949	0.000
N15.0 Balkan nephropathy	0.050	0.949	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.951	0.049
N10 Acute tubulo-interstitial nephritis	0.049	0.951	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.048	0.952	0.000
N14.3 Nephropathy induced by heavy metals	0.048	0.952	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.048	0.952	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.048	0.952	0.000
N14.0 Analgesic nephropathy	0.048	0.952	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.048	0.952	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.048	0.952	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.048	0.952	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.048	0.952	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.048	0.952	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.048	0.952	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.048	0.952	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.952	0.048
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.953	0.046
Y44.7 Plasma substitutes	0.000	0.953	0.046
Y44.6 Natural blood and blood products	0.000	0.953	0.046
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.953	0.046
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.953	0.046
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.953	0.046
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.953	0.046
Y43.4 Immunosuppressive agents	0.000	0.954	0.046
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.955	0.045
Y46.6 Other and unspecified antiepileptics	0.000	0.955	0.044
Y44.2 Anticoagulants	0.000	0.956	0.044
Y46.8 Antispasticity drugs	0.000	0.956	0.044
Y46.7 Anti-Parkinsonism drugs	0.000	0.956	0.044
Y46.5 Valproic acid	0.000	0.956	0.044
Y46.3 Deoxybarbiturates	0.000	0.956	0.044
Y46.1 Oxazolidinediones	0.000	0.956	0.044
Y46.0 Succinimides	0.000	0.956	0.044
Y46.4 Iminostilbenes	0.000	0.956	0.044
Y40.7 Antifungal antibiotics, systemically used	0.000	0.956	0.044
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.958	0.042
Y56.9 Topical agent, unspecified	0.000	0.959	0.040
Y56.8 Other topical agents	0.000	0.959	0.040
Y56.7 Dental drugs, topically applied	0.000	0.959	0.040
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.959	0.040
Y56.5 Ophthalmological drugs and preparations	0.000	0.959	0.040
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.959	0.040
Y56.3 Emollients, demulcents and protectants	0.000	0.959	0.040
Y56.2 Local astringents and local detergents	0.000	0.959	0.040
Y56.1 Antipruritics	0.000	0.959	0.040
Y44.5 Thrombolytic drugs	0.000	0.960	0.040
Y43.9 Primarily systemic agent, unspecified	0.000	0.961	0.039
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.961	0.039
Y43.6 Enzymes, not elsewhere classified	0.000	0.961	0.039
Y43.5 Acidifying and alkalising agents	0.000	0.961	0.039
Y43.2 Antineoplastic natural products	0.000	0.961	0.039
Y43.1 Antineoplastic antimetabolites	0.000	0.961	0.039
Y42.5 Other oestrogens and progestogens	0.000	0.962	0.038
Y43.0 Antiallergic and antiemetic drugs	0.000	0.964	0.035
M54.57 Low back pain (Lumbosacral region)	0.034	0.966	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.967	0.032
Y46.2 Hydantoin derivatives	0.001	0.970	0.029
M54.5 Low back pain	0.028	0.972	0.000
M54.50 Low back pain (Multiple sites in spine)	0.026	0.974	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.026	0.974	0.000
I08 Multiple valve diseases	0.000	0.975	0.025
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.975	0.025
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.976	0.024
I08.8 Other multiple valve diseases	0.000	0.977	0.023
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.977	0.022
I08.0 Disorders of both mitral and aortic valves	0.000	0.977	0.023
M54.54 Low back pain-Thoracic	0.022	0.978	0.000
M54.53 Low back pain-Cervicothoracic	0.020	0.979	0.000
M54.52 Low back pain-Cervical	0.020	0.979	0.000
M54.51 Low back pain-Occipit-atl-axl	0.020	0.979	0.000
M54.55 Low back pain (Thoracolumbar region)	0.020	0.980	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.982	0.018
M54.1 Radiculopathy	0.018	0.982	0.000
M54 Dorsalgia	0.018	0.982	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.017	0.983	0.000
M54.56 Low back pain (Lumbar region)	0.017	0.983	0.000
M54.9 Dorsalgia, unspecified	0.017	0.983	0.000
M54.12 Radiculopathy (Cervical region)	0.017	0.983	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.016	0.984	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.984	0.016
M54.19 Radiculopathy (Site unspecified)	0.015	0.985	0.000
R47.8 Other and unspecified speech disturbances	0.015	0.985	0.000
M54.6 Pain in thoracic spine	0.015	0.985	0.000
R47.1 Dysarthria and anarthria	0.015	0.985	0.000
R47 Speech disturbances, not elsewhere classified	0.014	0.986	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.014	0.986	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.014	0.986	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.013	0.987	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.013	0.987	0.000
M54.14 Radiculopathy (Thoracic region)	0.013	0.987	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.013	0.987	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.013	0.987	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.013	0.987	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.013	0.987	0.000
M54.0 Panniculitis affecting regions of neck and back	0.013	0.987	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.013	0.987	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.013	0.987	0.000
M54.16 Radiculopathy (Lumbar region)	0.013	0.987	0.000
M54.8 Other dorsalgia	0.012	0.987	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.012	0.988	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.012	0.988	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.012	0.988	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.012	0.988	0.000
R47.0 Dysphasia and aphasia	0.011	0.989	0.000
M54.69 Pain in thoracic spine-Site unspe	0.011	0.989	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.011	0.989	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.011	0.989	0.000
M54.66 Pain in thoracic spine-Lumbar	0.011	0.989	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.011	0.989	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.011	0.989	0.000
M54.62 Pain in thoracic spine-Cervical	0.011	0.989	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.011	0.989	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.011	0.989	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.010	0.990	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.010	0.990	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.010	0.990	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.010	0.990	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.010	0.990	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.010	0.990	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.010	0.990	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.010	0.990	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.010	0.990	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.010	0.990	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.009	0.991	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.009	0.991	0.000
M54.86 Other dorsalgia (Lumbar region)	0.009	0.991	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.009	0.991	0.000
M54.84 Other dorsalgia (Thoracic region)	0.009	0.991	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.009	0.991	0.000
M54.82 Other dorsalgia (Cervical region)	0.009	0.991	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.009	0.991	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.009	0.991	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.991	0.009
I07 Rheumatic tricuspid valve diseases	0.000	0.991	0.009
I07.1 Tricuspid insufficiency	0.000	0.991	0.009
M54.89 Other dorsalgia (Site unspecified)	0.008	0.991	0.000
R47-R49 Symptoms and signs involving speech and voice	0.008	0.992	0.000
M54.2 Cervicalgia	0.008	0.992	0.000
B37.8 Candidiasis of other sites	0.007	0.993	0.000
R49 Voice disturbances	0.007	0.993	0.000
M54.3 Sciatica	0.007	0.993	0.000
R49.0 Dysphonia	0.007	0.993	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.993	0.006
I07.8 Other tricuspid valve diseases	0.000	0.993	0.006
I07.2 Tricuspid stenosis with insufficiency	0.000	0.993	0.006
I07.0 Tricuspid stenosis	0.000	0.993	0.006
M81.98 Osteoporosis, unspecified (Other)	0.006	0.993	0.000
R49.1 Aphonia	0.006	0.994	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.006	0.994	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.006	0.994	0.000
I09 Other rheumatic heart diseases	0.000	0.994	0.006
I06 Rheumatic aortic valve diseases	0.000	0.994	0.006
Q51.3 Bicornate uterus	0.006	0.994	0.000
M81.9 Osteoporosis, unspecified	0.006	0.994	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.994	0.006
M65.34 Trigger finger-Hand	0.006	0.994	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.006	0.994	0.000
M54.27 Cervicalgia-Lumbosacral	0.006	0.994	0.000
M54.26 Cervicalgia-Lumbar	0.006	0.994	0.000
M54.25 Cervicalgia-Thoracolumbar	0.006	0.994	0.000
M54.24 Cervicalgia-Thoracic	0.006	0.994	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.006	0.994	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.006	0.994	0.000
M54.20 Cervicalgia-Mult site	0.006	0.994	0.000
R49.2 Hypernasality and hyponasality	0.005	0.994	0.000
M54.4 Lumbago with sciatica	0.005	0.994	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.995	0.005
M54.29 Cervicalgia-Site unspe	0.005	0.995	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.005	0.995	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
R49.8 Other and unspecified voice disturbances	0.005	0.995	0.000
M54.35 Sciatica (Thoracolumbar region)	0.005	0.995	0.000
M54.34 Sciatica-Thoracic	0.005	0.995	0.000
M54.33 Sciatica-Cervicothoracic	0.005	0.995	0.000
M54.32 Sciatica-Cervical	0.005	0.995	0.000
M54.31 Sciatica-Occipit-atl-axl	0.005	0.995	0.000
M54.30 Sciatica (Multiple sites in spine)	0.005	0.995	0.000
K86.3 Pseudocyst of pancreas	0.005	0.995	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.005	0.995	0.000
Y43.3 Other antineoplastic drugs	0.000	0.995	0.005
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.995	0.005
R48.8 Other and unspecified symbolic dysfunctions	0.005	0.995	0.000
R48.2 Apraxia	0.005	0.995	0.000
R48.1 Agnosia	0.005	0.995	0.000
R48.0 Dyslexia and alexia	0.005	0.995	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.005	0.995	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.995	0.004
I09.2 Chronic rheumatic pericarditis	0.000	0.995	0.004
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.995	0.004
I09.0 Rheumatic myocarditis	0.000	0.995	0.004
N18.5 Chronic kidney disease, stage 5	0.000	0.995	0.005
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.995	0.004
I06.8 Other rheumatic aortic valve diseases	0.000	0.995	0.004
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.995	0.004
I06.0 Rheumatic aortic stenosis	0.000	0.995	0.004
I61.8 Other intracerebral haemorrhage	0.005	0.995	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.996	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.004	0.996	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.996	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.004	0.996	0.000
I61 Intracerebral haemorrhage	0.004	0.996	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.004	0.996	0.000
M54.44 Lumbago with sciatica-Thoracic	0.004	0.996	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.004	0.996	0.000
M54.42 Lumbago with sciatica-Cervical	0.004	0.996	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.004	0.996	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
M54.37 Sciatica (Lumbosacral region)	0.004	0.996	0.000
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
K86 Other diseases of pancreas	0.004	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.996	0.004
M81.96 Osteoporosis, unspecified (Lower leg)	0.004	0.996	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.004	0.996	0.000
I06.1 Rheumatic aortic insufficiency	0.000	0.996	0.004
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.004	0.996	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.996	0.004
Z49.1 Extracorporeal dialysis	0.000	0.996	0.004
I61.9 Intracerebral haemorrhage, unspecified	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.004	0.996	0.000
O75.9 Complication of labour and delivery, unspecified	0.000	0.996	0.004
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.996	0.004
O75.4 Other complications of obstetric surgery and procedures	0.000	0.996	0.004
O75.3 Other infection during labour	0.000	0.996	0.004
O75.1 Shock during or following labour and delivery	0.000	0.996	0.004
I61.4 Intracerebral haemorrhage in cerebellum	0.004	0.996	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.004	0.996	0.000
M65.3 Trigger finger	0.004	0.996	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.996	0.004
O75.0 Maternal distress during labour and delivery	0.000	0.996	0.003
L29.2 Pruritus vulvae	0.000	0.996	0.004
I05 Rheumatic mitral valve diseases	0.000	0.996	0.003
M54.49 Lumbago with sciatica (Site unspecified)	0.003	0.996	0.001
M81.1 Postoophorectomy osteoporosis	0.003	0.996	0.000
Q51.2 Other doubling of uterus	0.003	0.997	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.003	0.997	0.000
M50-M54 Other dorsopathies	0.003	0.997	0.000
N87.0 Mild cervical dysplasia	0.000	0.997	0.003
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
K82.1 Hydrops of gallbladder	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
K82.8 Other specified diseases of gallbladder	0.003	0.997	0.000
N18.0 End-stage renal disease	0.000	0.997	0.003
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.002	0.997	0.001
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
H57.0 Anomalies of pupillary function	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.003	0.997	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
K82 Other diseases of gallbladder	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
E87.5 Hyperkalaemia	0.000	0.997	0.003
M54.59 Low back pain (Site unspecified)	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M65.39 Trigger finger-Site unspec	0.003	0.997	0.000
M65.38 Trigger finger-Other	0.003	0.997	0.000
M65.37 Trigger finger-Ankle/foot	0.003	0.997	0.000
M65.36 Trigger finger-Lower leg	0.003	0.997	0.000
M65.35 Trigger finger-Pelvic/thigh	0.003	0.997	0.000
M65.33 Trigger finger-Forearm	0.003	0.997	0.000
M65.32 Trigger finger-Upper arm	0.003	0.997	0.000
M65.31 Trigger finger-Shldr region	0.003	0.997	0.000
M65.30 Trigger finger-Mult sites	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
O71 Other obstetric trauma	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.000	0.997	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
K82.3 Fistula of gallbladder	0.003	0.997	0.000
M53 Other dorsopathies, not elsewhere classified	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
K86.9 Disease of pancreas, unspecified	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.003	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.997	0.002
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.997	0.000
Z49 Care involving dialysis	0.000	0.997	0.003
O71.8 Other specified obstetric trauma	0.000	0.997	0.002
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Z49.2 Other dialysis	0.000	0.997	0.002
K86.1 Other chronic pancreatitis	0.002	0.997	0.000
M53.2 Spinal instabilities	0.002	0.997	0.000
Q54 Hypospadias	0.002	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations