TreeWAS – Variant ID: rs76866386

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	1.000	0.000	0.000
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K80.1 Calculus of gallbladder with other cholecystitis	1.000	0.000	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	1.000	0.000	0.000
K81.9 Cholecystitis, unspecified	1.000	0.000	0.000
K81.1 Chronic cholecystitis	1.000	0.000	0.000
K81.0 Acute cholecystitis	1.000	0.000	0.000
K82.8 Other specified diseases of gallbladder	1.000	0.000	0.000
K82.4 Cholesterolosis of gallbladder	1.000	0.000	0.000
K83.8 Other specified diseases of biliary tract	1.000	0.000	0.000
R10.1 Pain localised to upper abdomen	1.000	0.000	0.000
Z90.4 Acquired absence of other parts of digestive tract	1.000	0.000	0.000
K83 Other diseases of biliary tract	1.000	0.000	0.000
K82 Other diseases of gallbladder	1.000	0.000	0.000
K81 Cholecystitis	1.000	0.000	0.000
K80 Cholelithiasis	1.000	0.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000	0.000
K83.1 Obstruction of bile duct	1.000	0.000	0.000
K80.4 Calculus of bile duct with cholecystitis	0.996	0.004	0.000
K82.1 Hydrops of gallbladder	0.992	0.008	0.000
I25.1 Atherosclerotic heart disease	0.000	0.017	0.983
R94.5 Abnormal results of liver function studies	0.978	0.022	0.000
K65-K67 Diseases of peritoneum	0.973	0.027	0.000
K66 Other disorders of peritoneum	0.970	0.030	0.000
Chapter XI Diseases of the digestive system	0.968	0.032	0.000
K66.0 Peritoneal adhesions	0.968	0.032	0.000
K86 Other diseases of pancreas	0.964	0.036	0.000
I25 Chronic ischaemic heart disease	0.000	0.039	0.961
K65 Peritonitis	0.956	0.044	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.046	0.954
K40-K46 Hernia	0.948	0.052	0.000
I20 Angina pectoris	0.000	0.055	0.945
I20-I25 Ischaemic heart diseases	0.000	0.056	0.944
I20.9 Angina pectoris, unspecified	0.000	0.061	0.939
K65.0 Acute peritonitis	0.939	0.061	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.063	0.937
K85 Acute pancreatitis	0.932	0.068	0.000
I20.0 Unstable angina	0.000	0.074	0.926
K43 Ventral hernia	0.923	0.077	0.000
K86.8 Other specified diseases of pancreas	0.921	0.079	0.000
K82.9 Disease of gallbladder, unspecified	0.904	0.096	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.104	0.896
K35-K38 Diseases of appendix	0.884	0.116	0.000
K41 Femoral hernia	0.861	0.139	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.860	0.140	0.000
K85.1 Biliary acute pancreatitis	0.857	0.143	0.000
K65.8 Other peritonitis	0.848	0.152	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.847	0.153	0.000
K80.8 Other cholelithiasis	0.843	0.157	0.000
R94 Abnormal results of function studies	0.836	0.164	0.000
K86.9 Disease of pancreas, unspecified	0.831	0.169	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.170	0.830
K82.3 Fistula of gallbladder	0.826	0.174	0.000
K81.8 Other cholecystitis	0.819	0.181	0.000
R94.4 Abnormal results of kidney function studies	0.802	0.198	0.000
K46 Unspecified abdominal hernia	0.800	0.200	0.000
K82.0 Obstruction of gallbladder	0.799	0.201	0.000
K66.9 Disorder of peritoneum, unspecified	0.797	0.203	0.000
K38 Other diseases of appendix	0.790	0.210	0.000
R10 Abdominal and pelvic pain	0.779	0.221	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.772	0.228	0.000
R10.4 Other and unspecified abdominal pain	0.768	0.232	0.000
I24 Other acute ischaemic heart diseases	0.000	0.247	0.753
K35 Acute appendicitis	0.752	0.248	0.000
K85.8 Other acute pancreatitis	0.745	0.255	0.000
K86.1 Other chronic pancreatitis	0.739	0.261	0.000
K86.3 Pseudocyst of pancreas	0.737	0.263	0.000
K42 Umbilical hernia	0.736	0.264	0.000
I25.2 Old myocardial infarction	0.000	0.264	0.736
K83.0 Cholangitis	0.734	0.266	0.000
K80.3 Calculus of bile duct with cholangitis	0.717	0.283	0.000
K83.5 Biliary cyst	0.717	0.283	0.000
K83.4 Spasm of sphincter of Oddi	0.717	0.283	0.000
K83.3 Fistula of bile duct	0.717	0.283	0.000
K83.2 Perforation of bile duct	0.717	0.283	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.712	0.288	0.000
K36 Other appendicitis	0.709	0.291	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.298	0.702
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.301	0.699
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.697	0.302	0.000
K85.9 Acute pancreatitis, unspecified	0.696	0.304	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.694	0.306	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.306	0.694
K38.8 Other specified diseases of appendix	0.694	0.306	0.000
I25.6 Silent myocardial ischaemia	0.000	0.311	0.689
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.688	0.312	0.000
E78.6 Lipoprotein deficiency	0.000	0.316	0.684
E78.4 Other hyperlipidaemia	0.000	0.316	0.684
E78.3 Hyperchylomicronaemia	0.000	0.316	0.684
E78.1 Pure hyperglyceridaemia	0.000	0.316	0.684
K82.2 Perforation of gallbladder	0.684	0.316	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.323	0.677
R94.8 Abnormal results of function studies of other organs and systems	0.674	0.326	0.000
K85.3 Drug-induced acute pancreatitis	0.669	0.331	0.000
K85.2 Alcohol-induced acute pancreatitis	0.669	0.331	0.000
K85.0 Idiopathic acute pancreatitis	0.669	0.331	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.669	0.331	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.662	0.338	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.662	0.338	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.662	0.338	0.000
K43.4 Parastomal hernia with gangrene	0.662	0.338	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.662	0.338	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.662	0.338	0.000
K43.1 Ventral hernia with gangrene	0.662	0.338	0.000
R10.0 Acute abdomen	0.661	0.339	0.000
K83.9 Disease of biliary tract, unspecified	0.660	0.340	0.000
K66.1 Haemoperitoneum	0.648	0.352	0.000
K38.1 Appendicular concretions	0.634	0.366	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.631	0.368	0.000
K45 Other abdominal hernia	0.627	0.373	0.000
I25.3 Aneurysm of heart	0.000	0.379	0.621
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.617	0.383	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.617	0.383	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.617	0.383	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.617	0.383	0.000
I22 Subsequent myocardial infarction	0.000	0.391	0.609
E78.8 Other disorders of lipoprotein metabolism	0.000	0.393	0.607
R94.7 Abnormal results of other endocrine function studies	0.599	0.400	0.000
R94.6 Abnormal results of thyroid function studies	0.599	0.400	0.000
R94.2 Abnormal results of pulmonary function studies	0.599	0.400	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.599	0.400	0.000
R94.0 Abnormal results of function studies of central nervous system	0.599	0.400	0.000
I25.4 Coronary artery aneurysm	0.000	0.409	0.590
K66.8 Other specified disorders of peritoneum	0.590	0.410	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.586	0.413	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.420	0.580
K46.1 Unspecified abdominal hernia with gangrene	0.574	0.426	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.574	0.426	0.000
I20.8 Other forms of angina pectoris	0.000	0.432	0.568
K38.9 Disease of appendix, unspecified	0.567	0.433	0.000
K38.3 Fistula of appendix	0.567	0.433	0.000
K38.2 Diverticulum of appendix	0.567	0.433	0.000
K38.0 Hyperplasia of appendix	0.567	0.433	0.000
K86.2 Cyst of pancreas	0.550	0.450	0.000
I24.1 Dressler's syndrome	0.000	0.460	0.540
K42.1 Umbilical hernia with gangrene	0.528	0.472	0.000
K44 Diaphragmatic hernia	0.527	0.473	0.000
K35.3 Acute appendicitis with localized peritonitis	0.526	0.474	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.477	0.523
K35.8 Acute appendicitis, other and unspecified	0.522	0.478	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.514	0.486	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.514	0.486	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.499	0.501
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.500	0.500	0.000
K67.3 Tuberculous peritonitis	0.500	0.500	0.000
K67.2 Syphilitic peritonitis	0.500	0.500	0.000
K67.1 Gonococcal peritonitis	0.500	0.500	0.000
K67.0 Chlamydial peritonitis	0.500	0.500	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.514	0.485
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.514	0.485
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.514	0.485
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.514	0.485
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.514	0.485
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.514	0.485
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.514	0.485
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.514	0.485
I22.8 Subsequent myocardial infarction of other sites	0.000	0.521	0.479
K65.9 Peritonitis, unspecified	0.468	0.532	0.000
K37 Unspecified appendicitis	0.453	0.547	0.000
K45.1 Other specified abdominal hernia with gangrene	0.450	0.550	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.450	0.550	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.560	0.440
K35.9 Acute appendicitis, unspecified	0.417	0.583	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.587	0.413
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.596	0.404
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.397	0.603	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.389	0.611	0.000
K44.1 Diaphragmatic hernia with gangrene	0.378	0.622	0.000
K40 Inguinal hernia	0.373	0.627	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.350	0.649	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.348	0.652	0.000
R94.3 Abnormal results of cardiovascular function studies	0.345	0.655	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.664	0.336
R93 Abnormal findings on diagnostic imaging of other body structures	0.325	0.675	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.300	0.700	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.703	0.297
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.290	0.710	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.278	0.722	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.275	0.725	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.271	0.728	0.001
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.267	0.732	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.267	0.732	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.264	0.736	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.262	0.738	0.000
K50-K52 Noninfective enteritis and colitis	0.260	0.740	0.000
R10.2 Pelvic and perineal pain	0.250	0.750	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.240	0.760	0.000
K90-K93 Other diseases of the digestive system	0.238	0.762	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.237	0.763	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.233	0.767	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.231	0.769	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.224	0.776	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.217	0.783	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.216	0.784	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.214	0.785	0.000
I21 Acute myocardial infarction	0.000	0.800	0.200
K70-K77 Diseases of liver	0.192	0.808	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.170	0.829	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.831	0.169
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.159	0.841	0.000
K73 Chronic hepatitis, not elsewhere classified	0.148	0.852	0.000
K51 Ulcerative colitis	0.147	0.853	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.854	0.146
R90.0 Intracranial space-occupying lesion	0.144	0.856	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.856	0.144
K77 Liver disorders in diseases classified elsewhere	0.138	0.862	0.000
K71 Toxic liver disease	0.138	0.862	0.000
K51.5 Mucosal proctocolitis	0.138	0.862	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.134	0.865	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.134	0.866	0.000
K91.4 Colostomy and enterostomy malfunction	0.132	0.868	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.132	0.868	0.000
K52 Other non-infective gastro-enteritis and colitis	0.131	0.869	0.000
K91.1 Postgastric surgery syndromes	0.127	0.873	0.000
K75 Other inflammatory liver diseases	0.125	0.875	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.122	0.877	0.000
K93.1 Megacolon in Chagas' disease	0.122	0.877	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.122	0.877	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.118	0.882	0.000
K72 Hepatic failure, not elsewhere classified	0.117	0.883	0.000
K73.9 Chronic hepatitis, unspecified	0.116	0.884	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.114	0.886	0.000
K91.5 Postcholecystectomy syndrome	0.114	0.886	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.114	0.886	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.113	0.887	0.000
K76 Other diseases of liver	0.110	0.890	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.894	0.106
K73.8 Other chronic hepatitis, not elsewhere classified	0.106	0.894	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.106	0.894	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.106	0.894	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.106	0.894	0.000
R10.3 Pain localised to other parts of lower abdomen	0.106	0.894	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.105	0.895	0.000
K76.9 Liver disease, unspecified	0.104	0.896	0.000
K75.9 Inflammatory liver disease, unspecified	0.102	0.898	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.102	0.898	0.000
K71.9 Toxic liver disease, unspecified	0.099	0.901	0.000
K71.8 Toxic liver disease with other disorders of liver	0.099	0.901	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.099	0.901	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.099	0.901	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.099	0.901	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.099	0.901	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.099	0.901	0.000
K71.2 Toxic liver disease with acute hepatitis	0.099	0.901	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.099	0.901	0.000
K71.0 Toxic liver disease with cholestasis	0.099	0.901	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.099	0.901	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.099	0.901	0.000
K51.4 Pseudopolyposis of colon	0.098	0.902	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.902	0.098
K52.0 Gastro-enteritis and colitis due to radiation	0.097	0.903	0.000
K72.0 Acute and subacute hepatic failure	0.093	0.906	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.093	0.907	0.000
K75.8 Other specified inflammatory liver diseases	0.093	0.907	0.000
K52.3 Indeterminate colitis	0.091	0.909	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.089	0.910	0.000
K75.2 Nonspecific reactive hepatitis	0.089	0.910	0.000
K75.1 Phlebitis of portal vein	0.089	0.910	0.000
K90 Intestinal malabsorption	0.088	0.911	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.087	0.912	0.000
K52.1 Toxic gastro-enteritis and colitis	0.085	0.914	0.000
K72.1 Chronic hepatic failure	0.084	0.916	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.084	0.916	0.000
K51.8 Other ulcerative colitis	0.083	0.917	0.000
K75.4 Autoimmune hepatitis	0.082	0.918	0.000
K74 Fibrosis and cirrhosis of liver	0.081	0.919	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.921	0.079
K76.5 Hepatic veno-occlusive disease	0.079	0.921	0.000
K76.4 Peliosis hepatis	0.079	0.921	0.000
K76.3 Infarction of liver	0.079	0.921	0.000
K76.2 Central haemorrhagic necrosis of liver	0.079	0.921	0.000
K76.1 Chronic passive congestion of liver	0.079	0.921	0.000
K91.3 Postoperative intestinal obstruction	0.078	0.921	0.000
K76.7 Hepatorenal syndrome	0.077	0.923	0.000
K50 Crohn's disease [regional enteritis]	0.072	0.928	0.000
K51.2 Ulcerative (chronic) proctitis	0.066	0.934	0.000
K90.9 Intestinal malabsorption, unspecified	0.065	0.935	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.936	0.064
K90.8 Other intestinal malabsorption	0.064	0.936	0.000
K90.3 Pancreatic steatorrhoea	0.064	0.936	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.064	0.936	0.000
K90.1 Tropical sprue	0.064	0.936	0.000
K70 Alcoholic liver disease	0.063	0.937	0.000
K74.0 Hepatic fibrosis	0.058	0.941	0.000
K74.4 Secondary biliary cirrhosis	0.058	0.942	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.058	0.942	0.000
K74.1 Hepatic sclerosis	0.058	0.942	0.000
K75.0 Abscess of liver	0.057	0.942	0.001
K76.6 Portal hypertension	0.057	0.943	0.000
M54.39 Sciatica (Site unspecified)	0.054	0.946	0.000
K51.9 Ulcerative colitis, unspecified	0.053	0.947	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.947	0.053
K74.5 Biliary cirrhosis, unspecified	0.051	0.948	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.949	0.051
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.051	0.949	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.950	0.050
K50.1 Crohn's disease of large intestine	0.049	0.951	0.000
K50.8 Other Crohn's disease	0.048	0.952	0.000
K74.3 Primary biliary cirrhosis	0.047	0.953	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.953	0.047
Z95.0 Presence of cardiac pacemaker	0.000	0.954	0.046
K70.3 Alcoholic cirrhosis of liver	0.045	0.954	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.045	0.955	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.045	0.955	0.000
K76.8 Other specified diseases of liver	0.044	0.956	0.000
K70.0 Alcoholic fatty liver	0.044	0.956	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.957	0.043
K72.9 Hepatic failure, unspecified	0.041	0.958	0.001
K70.4 Alcoholic hepatic failure	0.040	0.959	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.039	0.961	0.000
K74.6 Other and unspecified cirrhosis of liver	0.039	0.961	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.961	0.039
N90.7 Vulvar cyst	0.039	0.961	0.000
K92 Other diseases of digestive system	0.037	0.963	0.000
K13 Other diseases of lip and oral mucosa	0.036	0.964	0.000
K12 Stomatitis and related lesions	0.036	0.964	0.000
K50.0 Crohn's disease of small intestine	0.033	0.967	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.967	0.033
K03 Other diseases of hard tissues of teeth	0.033	0.967	0.000
K05 Gingivitis and periodontal diseases	0.032	0.968	0.000
K13.0 Diseases of lips	0.032	0.968	0.000
K92.9 Disease of digestive system, unspecified	0.032	0.968	0.000
K00 Disorders of tooth development and eruption	0.032	0.968	0.000
K10 Other diseases of jaws	0.031	0.969	0.000
K07 Dentofacial anomalies [including malocclusion]	0.031	0.969	0.000
K12.0 Recurrent oral aphthae	0.031	0.969	0.000
K70.1 Alcoholic hepatitis	0.030	0.970	0.001
K14 Diseases of tongue	0.030	0.970	0.000
K55-K64 Other diseases of intestines	0.030	0.970	0.000
M54.3 Sciatica	0.030	0.970	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.029	0.971	0.000
K01 Embedded and impacted teeth	0.029	0.971	0.000
K12.3 Oral mucositis (ulcerative)	0.029	0.971	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.029	0.971	0.000
K04 Diseases of pulp and periapical tissues	0.029	0.971	0.000
K92.8 Other specified diseases of digestive system	0.028	0.972	0.000
K04.7 Periapical abscess without sinus	0.028	0.972	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.028	0.972	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.027	0.973	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.027	0.973	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.026	0.973	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.026	0.974	0.000
K13.5 Oral submucous fibrosis	0.026	0.974	0.000
K13.3 Hairy leukoplakia	0.026	0.974	0.000
K13.1 Cheek and lip biting	0.026	0.974	0.000
M79.67 Pain in limb (Ankle and foot)	0.026	0.974	0.000
K05.6 Periodontal disease, unspecified	0.026	0.974	0.000
K00.0 Anodontia	0.026	0.974	0.000
K70.9 Alcoholic liver disease, unspecified	0.025	0.974	0.000
K01.0 Embedded teeth	0.025	0.975	0.000
K14.6 Glossodynia	0.025	0.975	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.975	0.025
K06 Other disorders of gingiva and edentulous alveolar ridge	0.024	0.975	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.975	0.025
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.025	0.975	0.000
K07.3 Anomalies of tooth position	0.024	0.976	0.000
N90.5 Atrophy of vulva	0.024	0.976	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.023	0.976	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.023	0.976	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.023	0.976	0.000
K03.6 Deposits [accretions] on teeth	0.023	0.976	0.000
K03.5 Ankylosis of teeth	0.023	0.976	0.000
K03.4 Hypercementosis	0.023	0.976	0.000
K03.3 Pathological resorption of teeth	0.023	0.976	0.000
K03.2 Erosion of teeth	0.023	0.976	0.000
K03.1 Abrasion of teeth	0.023	0.976	0.000
K03.0 Excessive attrition of teeth	0.023	0.976	0.000
K56.6 Other and unspecified intestinal obstruction	0.024	0.976	0.000
K10.2 Inflammatory conditions of jaws	0.023	0.976	0.000
K12.1 Other forms of stomatitis	0.023	0.977	0.000
K05.2 Acute periodontitis	0.023	0.977	0.000
K05.5 Other periodontal diseases	0.023	0.977	0.000
K05.4 Periodontosis	0.023	0.977	0.000
K05.0 Acute gingivitis	0.023	0.977	0.000
K00.9 Disorder of tooth development, unspecified	0.023	0.977	0.000
K00.8 Other disorders of tooth development	0.023	0.977	0.000
K00.7 Teething syndrome	0.023	0.977	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.023	0.977	0.000
K00.4 Disturbances in tooth formation	0.023	0.977	0.000
K00.3 Mottled teeth	0.023	0.977	0.000
K00.2 Abnormalities of size and form of teeth	0.023	0.977	0.000
K00.1 Supernumerary teeth	0.023	0.977	0.000
E70-E90 Metabolic disorders	0.000	0.977	0.023
K07.4 Malocclusion, unspecified	0.023	0.977	0.000
Z82.3 Family history of stroke	0.000	0.977	0.023
K10.9 Disease of jaws, unspecified	0.023	0.977	0.000
K10.3 Alveolitis of jaws	0.023	0.977	0.000
K10.1 Giant cell granuloma, central	0.023	0.977	0.000
K10.0 Developmental disorders of jaws	0.023	0.977	0.000
K07.9 Dentofacial anomaly, unspecified	0.023	0.977	0.000
K07.8 Other dentofacial anomalies	0.023	0.977	0.000
K07.5 Dentofacial functional abnormalities	0.023	0.977	0.000
K07.2 Anomalies of dental arch relationship	0.023	0.977	0.000
K07.0 Major anomalies of jaw size	0.023	0.977	0.000
K12.2 Cellulitis and abscess of mouth	0.023	0.977	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.022	0.978	0.000
K09 Cysts of oral region, not elsewhere classified	0.022	0.978	0.000
K05.1 Chronic gingivitis	0.022	0.978	0.000
K14.5 Plicated tongue	0.022	0.978	0.000
K14.4 Atrophy of tongue papillae	0.022	0.978	0.000
K14.3 Hypertrophy of tongue papillae	0.022	0.978	0.000
K14.2 Median rhomboid glossitis	0.022	0.978	0.000
K14.1 Geographic tongue	0.022	0.978	0.000
M54.37 Sciatica (Lumbosacral region)	0.022	0.978	0.000
K56.0 Paralytic ileus	0.022	0.978	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.022	0.978	0.000
K63 Other diseases of intestine	0.022	0.978	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.021	0.978	0.000
M54.35 Sciatica (Thoracolumbar region)	0.021	0.978	0.000
M54.34 Sciatica-Thoracic	0.021	0.978	0.000
M54.33 Sciatica-Cervicothoracic	0.021	0.978	0.000
M54.32 Sciatica-Cervical	0.021	0.978	0.000
M54.31 Sciatica-Occipit-atl-axl	0.021	0.978	0.000
M54.30 Sciatica (Multiple sites in spine)	0.021	0.978	0.000
K56.3 Gallstone ileus	0.022	0.978	0.000
K63.2 Fistula of intestine	0.021	0.979	0.000
N90.4 Leukoplakia of vulva	0.021	0.979	0.000
K04.3 Abnormal hard tissue formation in pulp	0.021	0.979	0.000
K04.2 Pulp degeneration	0.021	0.979	0.000
K04.1 Necrosis of pulp	0.021	0.979	0.000
K04.0 Pulpitis	0.021	0.979	0.000
M54.36 Sciatica (Lumbar region)	0.021	0.979	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.021	0.979	0.000
K14.0 Glossitis	0.021	0.979	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.021	0.979	0.000
K10.8 Other specified diseases of jaws	0.020	0.980	0.000
N90.6 Hypertrophy of vulva	0.020	0.980	0.000
K05.3 Chronic periodontitis	0.020	0.980	0.000
K14.9 Disease of tongue, unspecified	0.020	0.980	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.980	0.020
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.020	0.980	0.000
N90.3 Dysplasia of vulva, unspecified	0.020	0.980	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.020	0.980	0.000
N90.1 Moderate vulvar dysplasia	0.020	0.980	0.000
N90.0 Mild vulvar dysplasia	0.020	0.980	0.000
K07.6 Temporomandibular joint disorders	0.019	0.980	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.981	0.019
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.019	0.981	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.019	0.981	0.000
K14.8 Other diseases of tongue	0.019	0.981	0.000
K63.1 Perforation of intestine (nontraumatic)	0.019	0.981	0.000
K11 Diseases of salivary glands	0.018	0.981	0.000
K56.1 Intussusception	0.018	0.982	0.000
K02 Dental caries	0.018	0.982	0.000
K04.6 Periapical abscess with sinus	0.018	0.982	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.018	0.982	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.018	0.982	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.018	0.982	0.000
K06.1 Gingival enlargement	0.018	0.982	0.000
K06.0 Gingival recession	0.018	0.982	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.982	0.018
Z82.1 Family history of blindness and visual loss	0.000	0.982	0.018
K50.9 Crohn's disease, unspecified	0.018	0.982	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.982	0.018
K00.6 Disturbances in tooth eruption	0.017	0.982	0.000
K58 Irritable bowel syndrome	0.017	0.983	0.000
K05.22 Aggressive periodontitis, generalized	0.017	0.983	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.983	0.017
K63.0 Abscess of intestine	0.017	0.983	0.000
E84 Cystic fibrosis	0.000	0.983	0.017
E79 Disorders of purine and pyrimidine metabolism	0.000	0.983	0.017
E77 Disorders of glycoprotein metabolism	0.000	0.983	0.017
E76 Disorders of glycosaminoglycan metabolism	0.000	0.983	0.017
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.983	0.017
E74 Other disorders of carbohydrate metabolism	0.000	0.983	0.017
E72 Other disorders of amino-acid metabolism	0.000	0.983	0.017
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.983	0.017
E70 Disorders of aromatic amino-acid metabolism	0.000	0.983	0.017
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.983	0.017
K59 Other functional intestinal disorders	0.016	0.984	0.000
K09.9 Cyst of oral region, unspecified	0.016	0.984	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.016	0.984	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.016	0.984	0.000
K63.3 Ulcer of intestine	0.016	0.984	0.000
E83 Disorders of mineral metabolism	0.000	0.984	0.016
K64.9 Haemorrhoids, unspecified	0.016	0.984	0.000
K64.8 Other specified haemorrhoids	0.016	0.984	0.000
K64.5 Perianal venous thrombosis	0.016	0.984	0.000
K64.4 Residual haemorrhoidal skin tags	0.016	0.984	0.000
K64.3 Fourth degree haemorrhoids	0.016	0.984	0.000
K64.2 Third degree haemorrhoids	0.016	0.984	0.000
K64.1 Second degree haemorrhoids	0.016	0.984	0.000
K64.0 First degree haemorrhoids	0.016	0.984	0.000
K63.4 Enteroptosis	0.016	0.984	0.000
E73 Lactose intolerance	0.000	0.984	0.016
K59.3 Megacolon, not elsewhere classified	0.016	0.984	0.000
Z82.2 Family history of deafness and hearing loss	0.000	0.985	0.015
E88 Other metabolic disorders	0.000	0.985	0.015
K11.9 Disease of salivary gland, unspecified	0.015	0.985	0.000
K56.4 Other impaction of intestine	0.015	0.985	0.000
Z90.8 Acquired absence of other organs	0.015	0.985	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.985	0.014
K11.8 Other diseases of salivary glands	0.014	0.986	0.000
N41.1 Chronic prostatitis	0.014	0.986	0.000
N41.0 Acute prostatitis	0.014	0.986	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.986	0.014
K11.7 Disturbances of salivary secretion	0.013	0.986	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations