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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77052778
log Bayes Factor = 6.40134
Chromosome 2   position 171,579,290  (GRCh37) Explore rs77052778 on Ensembl!
Variant rs77052778 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
M54 Dorsalgia
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
M24 Other specific joint derangements
0.990 0.010 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.984 0.016 0.000
M54.3 Sciatica
0.980 0.020 0.000
F30-F39 Mood [affective] disorders
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.976 0.024 0.000
J90-J94 Other diseases of pleura
0.974 0.026 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.970 0.030 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.968 0.032 0.000
M25 Other joint disorders, not elsewhere classified
0.968 0.032 0.000
F31 Bipolar affective disorder
0.963 0.037 0.000
Chapter XXII Codes for special purposes
0.958 0.042 0.000
J93 Pneumothorax
0.957 0.043 0.000
M54.36 Sciatica (Lumbar region)
0.953 0.047 0.000
S40-S49 Injuries to the shoulder and upper arm
0.953 0.047 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.947 0.053 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.945 0.055 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.943 0.057 0.000
J93.9 Pneumothorax, unspecified
0.943 0.057 0.000
S90-S99 Injuries to the ankle and foot
0.937 0.063 0.000
J92 Pleural plaque
0.937 0.063 0.000
F20 Schizophrenia
0.934 0.066 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.933 0.067 0.000
M24.1 Other articular cartilage disorders
0.927 0.073 0.000
M20 Acquired deformities of fingers and toes
0.925 0.075 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.925 0.075 0.000
M54.5 Low back pain
0.924 0.076 0.000
M54.39 Sciatica (Site unspecified)
0.924 0.076 0.000
L20-L30 Dermatitis and eczema
0.914 0.086 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.914 0.086 0.000
M20.5 Other deformities of toe(s) (acquired)
0.912 0.088 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.908 0.092 0.000
M23 Internal derangement of knee
0.906 0.094 0.000
J84 Other interstitial pulmonary diseases
0.905 0.095 0.000
W00-W19 Falls
0.904 0.096 0.000
J90 Pleural effusion, not elsewhere classified
0.899 0.101 0.000
J92.9 Pleural plaque without asbestos
0.898 0.102 0.000
M25.4 Effusion of joint
0.894 0.106 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.887 0.113 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.886 0.114 0.000
S32 Fracture of lumbar spine and pelvis
0.885 0.115 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.883 0.117 0.000
T92 Sequelae of injuries of upper limb
0.882 0.118 0.000
M23.3 Other meniscus derangements
0.882 0.118 0.000
M32 Systemic lupus erythematosus
0.879 0.121 0.000
U51 Admission status on psychiatric patients
0.879 0.121 0.000
M24.5 Contracture of joint
0.876 0.124 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.876 0.124 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.872 0.128 0.000
Y86 Sequelae of other accidents
0.870 0.130 0.000
F20.9 Schizophrenia, unspecified
0.870 0.130 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.869 0.131 0.000
Y88 Sequelae of surgical and medical care as external cause
0.868 0.132 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.860 0.140 0.000
M54.57 Low back pain (Lumbosacral region)
0.860 0.140 0.000
L29 Pruritus
0.859 0.141 0.000
M21 Other acquired deformities of limbs
0.854 0.146 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.853 0.147 0.000
T90 Sequelae of injuries of head
0.851 0.149 0.000
M20.2 Hallux rigidus
0.850 0.150 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.849 0.151 0.000
S43.0 Dislocation of shoulder joint
0.846 0.154 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.845 0.155 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.839 0.161 0.000
T98 Sequelae of other and unspecified effects of external causes
0.838 0.162 0.000
S80-S89 Injuries to the knee and lower leg
0.835 0.165 0.000
F20.0 Paranoid schizophrenia
0.831 0.169 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.831 0.169 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.830 0.170 0.000
M54.9 Dorsalgia, unspecified
0.826 0.174 0.000
W17 Other fall from one level to another
0.825 0.175 0.000
S10-S19 Injuries to the neck
0.824 0.176 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.823 0.177 0.000
M54.1 Radiculopathy
0.818 0.182 0.000
M24.2 Disorder of ligament
0.816 0.184 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.815 0.185 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.813 0.187 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.813 0.187 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.812 0.187 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.812 0.188 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.810 0.190 0.000
M25.5 Pain in joint
0.810 0.190 0.000
M54.56 Low back pain (Lumbar region)
0.809 0.191 0.000
M31 Other necrotising vasculopathies
0.809 0.191 0.000
S43.1 Dislocation of acromioclavicular joint
0.806 0.194 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.804 0.196 0.000
T79-T79 Certain early complications of trauma
0.804 0.196 0.000
F31.9 Bipolar affective disorder, unspecified
0.801 0.199 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.800 0.200 0.000
F52.2 Failure of genital response
0.800 0.200 0.000
M25.9 Joint disorder, unspecified
0.794 0.206 0.000
F32 Depressive episode
0.794 0.206 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.793 0.207 0.000
U80 Agent resistant to penicillin and related antibiotics
0.792 0.208 0.000
M25.0 Haemarthrosis
0.791 0.209 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.789 0.211 0.000
S32.5 Fracture of pubis
0.789 0.211 0.000
F25 Schizoaffective disorders
0.788 0.211 0.000
W50-W64 Exposure to animate mechanical forces
0.786 0.214 0.000
S92 Fracture of foot, except ankle
0.786 0.214 0.000
M25.40 Effusion of joint (Multiple sites)
0.784 0.216 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.783 0.217 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.783 0.217 0.000
S20-S29 Injuries to the thorax
0.781 0.218 0.000
M21.3 Wrist or foot drop (acquired)
0.780 0.220 0.000
Y52 Agents primarily affecting the cardiovascular system
0.778 0.222 0.000
J95-J99 Other diseases of the respiratory system
0.778 0.222 0.000
V01-V09 Pedestrian injured in transport accident
0.777 0.223 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.774 0.226 0.000
M40-M43 Deforming dorsopathies
0.772 0.228 0.000
L29.9 Pruritus, unspecified
0.770 0.230 0.000
J93.1 Other spontaneous pneumothorax
0.770 0.230 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.770 0.230 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.769 0.231 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.768 0.232 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.768 0.232 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.767 0.233 0.000
V10-V19 Pedal cyclist injured in transport accident
0.766 0.234 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.766 0.234 0.000
F29 Unspecified nonorganic psychosis
0.764 0.236 0.000
L10-L14 Bullous disorders
0.763 0.237 0.000
M33 Dermatopolymyositis
0.763 0.237 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.763 0.237 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.762 0.238 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.762 0.238 0.000
L27 Dermatitis due to substances taken internally
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.760 0.240 0.000
M50 Cervical disk disorders
0.759 0.241 0.000
L08 Other local infections of skin and subcutaneous tissue
0.758 0.242 0.000
X60-X84 Intentional self-harm
0.758 0.242 0.000
O24 Diabetes mellitus in pregnancy
0.758 0.242 0.000
J92.0 Pleural plaque with presence of asbestos
0.758 0.242 0.000
S90 Superficial injury of ankle and foot
0.756 0.244 0.000
T92.0 Sequelae of open wound of upper limb
0.755 0.245 0.000
O26.8 Other specified pregnancy-related conditions
0.755 0.245 0.000
M25.46 Effusion of joint (Lower leg)
0.753 0.247 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.753 0.247 0.000
U51.1 Previously admitted to a psychiatric hospital of the provider
0.751 0.249 0.000
M15-M19 Arthrosis
0.751 0.249 0.000
Y40 Systemic antibiotics
0.750 0.250 0.000
X50-X57 Overexertion, travel and privation
0.747 0.253 0.000
S32.4 Fracture of acetabulum
0.747 0.253 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.745 0.255 0.000
M23.8 Other internal derangements of knee
0.745 0.255 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.744 0.255 0.000
W17.4 Street and highway
0.743 0.257 0.000
M25.56 Pain in joint (Lower leg)
0.743 0.257 0.000
M25.3 Other instability of joint
0.741 0.259 0.000
M24.6 Ankylosis of joint
0.741 0.259 0.000
S91 Open wound of ankle and foot
0.741 0.259 0.000
W06 Fall involving bed
0.741 0.259 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.738 0.262 0.000
S32.3 Fracture of ilium
0.737 0.263 0.000
T91 Sequelae of injuries of neck and trunk
0.736 0.264 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.736 0.264 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.735 0.265 0.000
F39 Unspecified mood [affective] disorder
0.735 0.265 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.735 0.265 0.000
M54.55 Low back pain (Thoracolumbar region)
0.733 0.267 0.000
S86 Injury of muscle and tendon at lower leg level
0.733 0.267 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.733 0.267 0.000
S99 Other and unspecified injuries of ankle and foot
0.732 0.268 0.000
F80-F89 Disorders of psychological development
0.731 0.269 0.000
T40.2 Other opioids
0.730 0.270 0.000
L21 Seborrhoeic dermatitis
0.730 0.270 0.000
L03 Cellulitis
0.730 0.270 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.729 0.271 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.729 0.271 0.000
T00-T07 Injuries involving multiple body regions
0.729 0.271 0.000
M30 Polyarteritis nodosa and related conditions
0.727 0.273 0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
0.727 0.273 0.000
M54.4 Lumbago with sciatica
0.727 0.273 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.727 0.273 0.000
Y42.5 Other oestrogens and progestogens
0.725 0.275 0.000
M80-M85 Disorders of bone density and structure
0.724 0.276 0.000
M65-M68 Disorders of synovium and tendon
0.724 0.276 0.000
T43.2 Other and unspecified antidepressants
0.722 0.278 0.000
M21.2 Flexion deformity
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.720 0.280 0.000
S32.50 Fracture of pubis (closed)
0.720 0.280 0.000
L29.2 Pruritus vulvae
0.719 0.281 0.000
S31 Open wound of abdomen, lower back and pelvis
0.718 0.281 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.718 0.282 0.000
T90.5 Sequelae of intracranial injury
0.718 0.282 0.000
M70-M79 Other soft tissue disorders
0.718 0.282 0.000
M54.12 Radiculopathy (Cervical region)
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
M24.57 Contracture of joint (Ankle and foot)
0.716 0.284 0.000
M17 Gonarthrosis [arthrosis of knee]
0.715 0.285 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.715 0.285 0.000
S81 Open wound of lower leg
0.715 0.285 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
S37 Injury of urinary and pelvic organs
0.714 0.286 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.713 0.287 0.000
S36 Injury of intra-abdominal organs
0.712 0.287 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.712 0.288 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.712 0.288 0.000
Y89 Sequelae of other external causes
0.712 0.288 0.000
O00-O08 Pregnancy with abortive outcome
0.712 0.288 0.000
M91-M94 Chondropathies
0.711 0.288 0.000
U80.1 Methicillin resistant agent
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
M54.8 Other dorsalgia
0.711 0.289 0.000
M54.0 Panniculitis affecting regions of neck and back
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
M24.9 Joint derangement, unspecified
0.710 0.290 0.000
M24.7 Protrusio acetabuli
0.710 0.290 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.710 0.290 0.000
M17.9 Gonarthrosis, unspecified
0.708 0.292 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.708 0.292 0.000
L05 Pilonidal cyst
0.708 0.292 0.000
F32.1 Moderate depressive episode
0.707 0.293 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.706 0.294 0.000
L29.8 Other pruritus
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.705 0.295 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.705 0.295 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.703 0.296 0.000
M24.56 Contracture of joint (Lower leg)
0.703 0.297 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.702 0.298 0.000
M54.35 Sciatica (Thoracolumbar region)
0.702 0.298 0.000
M54.34 Sciatica-Thoracic
0.702 0.298 0.000
M54.33 Sciatica-Cervicothoracic
0.702 0.298 0.000
M54.32 Sciatica-Cervical
0.702 0.298 0.000
M54.31 Sciatica-Occipit-atl-axl
0.702 0.298 0.000
M54.30 Sciatica (Multiple sites in spine)
0.702 0.298 0.000
L30 Other dermatitis
0.701 0.299 0.000
F38 Other mood [affective] disorders
0.701 0.299 0.000
F34 Persistent mood [affective] disorders
0.701 0.299 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.700 0.300 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.699 0.301 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.698 0.302 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.698 0.302 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.697 0.302 0.000
M25.57 Pain in joint (Ankle and foot)
0.697 0.303 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.697 0.303 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.696 0.304 0.000
S41 Open wound of shoulder and upper arm
0.696 0.304 0.000
W20-W49 Exposure to inanimate mechanical forces
0.695 0.304 0.000
T95 Sequelae of burns, corrosions and frostbite
0.696 0.304 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.696 0.304 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.696 0.304 0.000
M24.54 Contracture of joint (Hand)
0.695 0.305 0.000
M53 Other dorsopathies, not elsewhere classified
0.695 0.305 0.000
F28 Other nonorganic psychotic disorders
0.694 0.306 0.000
F24 Induced delusional disorder
0.694 0.306 0.000
F21 Schizotypal disorder
0.694 0.306 0.000
M25.2 Flail joint
0.694 0.306 0.000
M25.1 Fistula of joint
0.694 0.306 0.000
Q66 Congenital deformities of feet
0.693 0.307 0.000
M31.6 Other giant cell arteritis
0.693 0.307 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.692 0.308 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.690 0.310 0.000
F23 Acute and transient psychotic disorders
0.690 0.310 0.000
F31.8 Other bipolar affective disorders
0.690 0.310 0.000
F31.7 Bipolar affective disorder, currently in remission
0.690 0.310 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.690 0.310 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.688 0.312 0.000
Q00-Q07 Congenital malformations of the nervous system
0.687 0.313 0.000
J93.0 Spontaneous tension pneumothorax
0.686 0.314 0.000
J20-J22 Other acute lower respiratory infections
0.686 0.314 0.000
M25.43 Effusion of joint (Forearm)
0.686 0.314 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.685 0.314 0.000
O02 Other abnormal products of conception
0.685 0.315 0.000
L03.9 Cellulitis, unspecified
0.685 0.315 0.000
L25 Unspecified contact dermatitis
0.684 0.316 0.000
S48 Traumatic amputation of shoulder and upper arm
0.683 0.317 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.683 0.317 0.000
S44 Injury of nerves at shoulder and upper arm level
0.683 0.317 0.000
S47 Crushing injury of shoulder and upper arm
0.683 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.683 0.317 0.000
S12 Fracture of neck
0.682 0.318 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.681 0.319 0.000
Y00-Y09 Assault
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.677 0.323 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.676 0.324 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.676 0.324 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.676 0.324 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.676 0.324 0.000
S91.1 Open wound of toe(s) without damage to nail
0.676 0.324 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.675 0.324 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.675 0.325 0.000
M86-M90 Other osteopathies
0.675 0.325 0.000
M23.1 Discoid meniscus (congenital)
0.674 0.326 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.674 0.326 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.673 0.327 0.000
S98 Traumatic amputation of ankle and foot
0.672 0.328 0.000
S97 Crushing injury of ankle and foot
0.672 0.328 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.672 0.328 0.000
S95 Injury of blood vessels at ankle and foot level
0.672 0.328 0.000
S94 Injury of nerves at ankle and foot level
0.672 0.328 0.000
M00-M03 Infectious arthropathies
0.671 0.328 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.671 0.329 0.000
M23.0 Cystic meniscus
0.670 0.330 0.000
F20.8 Other schizophrenia
0.669 0.331 0.000
F20.6 Simple schizophrenia
0.669 0.331 0.000
F20.5 Residual schizophrenia
0.669 0.331 0.000
F20.4 Postschizophrenic depression
0.669 0.331 0.000
F20.3 Undifferentiated schizophrenia
0.669 0.331 0.000
F20.2 Catatonic schizophrenia
0.669 0.331 0.000
F20.1 Hebephrenic schizophrenia
0.669 0.331 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.669 0.331 0.000
M99 Biomechanical lesions, not elsewhere classified
0.668 0.332 0.000
M24.0 Loose body in joint
0.667 0.333 0.000
T39.1 4-Aminophenol derivatives
0.667 0.333 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.666 0.334 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.666 0.334 0.000
O28 Abnormal findings on antenatal screening of mother
0.666 0.334 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.665 0.335 0.000
M24.18 Other articular cartilage disorders (Other)
0.665 0.335 0.000
M24.14 Other articular cartilage disorders (Hand)
0.665 0.335 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.665 0.335 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.665 0.335 0.000
M25.06 Haemarthrosis (Lower leg)
0.664 0.336 0.000
T90.1 Sequelae of open wound of head
0.664 0.336 0.000
W10 Fall on and from stairs and steps
0.664 0.336 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.664 0.336 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.663 0.337 0.000
U50 Level of care administered to neonates
0.663 0.337 0.000
U07 Emergency use of U07
0.663 0.337 0.000
U06 Emergency use of U06
0.663 0.337 0.000
U04 Severe acute respiratory syndrome [SARS]
0.663 0.337 0.000
U52 First in a series of a regular day/night admissions
0.663 0.337 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.663 0.337 0.000
M54.54 Low back pain-Thoracic
0.663 0.337 0.000
M54.53 Low back pain-Cervicothoracic
0.663 0.337 0.000
M54.52 Low back pain-Cervical
0.663 0.337 0.000
M54.51 Low back pain-Occipit-atl-axl
0.663 0.337 0.000
V80-V89 Other land transport accidents
0.662 0.338 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.660 0.339 0.000
M54.6 Pain in thoracic spine
0.659 0.341 0.000
S10 Superficial injury of neck
0.659 0.341 0.000
V20-V29 Motorcycle rider injured in transport accident
0.659 0.341 0.000
J80 Adult respiratory distress syndrome
0.658 0.342 0.000
Y52.1 Calcium-channel blockers
0.657 0.343 0.000
M25.54 Pain in joint (Hand)
0.657 0.343 0.000
L03.2 Cellulitis of face
0.657 0.343 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.657 0.343 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.656 0.344 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.656 0.344 0.000
L24 Irritant contact dermatitis
0.655 0.344 0.000
L23 Allergic contact dermatitis
0.655 0.344 0.000
L20 Atopic dermatitis
0.655 0.344 0.000
L26 Exfoliative dermatitis
0.655 0.344 0.000
L22 Diaper [napkin] dermatitis
0.655 0.344 0.000
F60-F69 Disorders of adult personality and behaviour
0.655 0.345 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.655 0.345 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.655 0.345 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.655 0.345 0.000
S43.4 Sprain and strain of shoulder joint
0.655 0.345 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.655 0.345 0.000
S43.2 Dislocation of sternoclavicular joint
0.655 0.345 0.000
W08 Fall involving other furniture
0.654 0.346 0.000
F33 Recurrent depressive disorder
0.654 0.346 0.000
J60-J70 Lung diseases due to external agents
0.654 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.653 0.347 0.000
W13 Fall from, out of or through building or structure
0.653 0.347 0.000
F50 Eating disorders
0.653 0.347 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.651 0.349 0.000
F51 Nonorganic sleep disorders
0.651 0.349 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.651 0.349 0.000
F55 Abuse of non-dependence-producing substances
0.651 0.349 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.651 0.349 0.000
W17.5 Trade and service area
0.651 0.349 0.000
T40.6 Other and unspecified narcotics
0.651 0.349 0.000
M23.9 Internal derangement of knee, unspecified
0.650 0.350 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
J84.8 Other specified interstitial pulmonary diseases
0.649 0.351 0.000
J84.0 Alveolar and parietoalveolar conditions
0.649 0.351 0.000
F25.0 Schizoaffective disorder, manic type
0.649 0.351 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.649 0.351 0.000
J81 Pulmonary oedema
0.648 0.351 0.000
S32.1 Fracture of sacrum
0.648 0.352 0.000
S32.40 Fracture of acetabulum (closed)
0.648 0.352 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.648 0.352 0.000
W15 Fall from cliff
0.648 0.352 0.000
W14 Fall from tree
0.648 0.352 0.000
W12 Fall on and from scaffolding
0.648 0.352 0.000
W11 Fall on and from ladder
0.648 0.352 0.000
W09 Fall involving playground equipment
0.648 0.352 0.000
W05 Fall involving wheelchair
0.648 0.352 0.000
W04 Fall while being carried or supported by other persons
0.648 0.352 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.648 0.352 0.000
W00 Fall on same level involving ice and snow
0.648 0.352 0.000
F22 Persistent delusional disorders
0.647 0.352 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.648 0.352 0.000
M25.47 Effusion of joint (Ankle and foot)
0.646 0.354 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.646 0.354 0.000
M54.50 Low back pain (Multiple sites in spine)
0.645 0.355 0.000
O02.1 Missed abortion
0.645 0.355 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.644 0.356 0.000
J94 Other pleural conditions
0.644 0.356 0.000
S11 Open wound of neck
0.643 0.357 0.000
M60-M63 Disorders of muscles
0.642 0.358 0.000
J98 Other respiratory disorders
0.642 0.358 0.000
M25.49 Effusion of joint (Site unspecified)
0.641 0.359 0.000
M25.48 Effusion of joint (Other)
0.641 0.359 0.000
M25.44 Effusion of joint (Hand)
0.641 0.359 0.000
M25.42 Effusion of joint (Upper arm)
0.641 0.359 0.000
M25.41 Effusion of joint (Shoulder region)
0.641 0.359 0.000
T18 Foreign body in alimentary tract
0.641 0.359 0.000
S92.3 Fracture of metatarsal bone
0.641 0.359 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.640 0.360 0.000
W55 Bitten or struck by other mammals
0.640 0.360 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.639 0.361 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.638 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.638 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.638 0.362 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.637 0.363 0.000
M25.94 Joint disorder, unspecified (Hand)
0.636 0.364 0.000
Y59 Other and unspecified vaccines and biological substances
0.636 0.364 0.000
Y58 Bacterial vaccines
0.636 0.364 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.636 0.364 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.636 0.364 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.636 0.364 0.000
W07 Fall involving chair
0.635 0.365 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.635 0.365 0.000
W18 Other fall on same level
0.635 0.365 0.000
Q28 Other congenital malformations of circulatory system
0.635 0.365 0.000
M34 Systemic sclerosis
0.634 0.365 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.634 0.365 0.000
S32.2 Fracture of coccyx
0.634 0.365 0.000
S40 Superficial injury of shoulder and upper arm
0.634 0.365 0.000
M41 Scoliosis
0.633 0.367 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.633 0.367 0.000
M23.37 Other meniscus derangements-Capsular lig
0.632 0.367 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.631 0.369 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.630 0.369 0.000
M32.8 Other forms of systemic lupus erythematosus
0.630 0.369 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.630 0.369 0.000
S32.30 Fracture of ilium (closed)
0.630 0.369 0.000
U51.2 Previously admitted to a psychiatric hospital of another provider
0.630 0.369 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.630 0.370 0.000
M23.4 Loose body in knee
0.630 0.370 0.000
J93.8 Other pneumothorax
0.629 0.371 0.000
Q66.8 Other congenital deformities of feet
0.629 0.371 0.000
T16 Foreign body in ear
0.629 0.371 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.628 0.372 0.000
M24.59 Contracture of joint (Site unspecified)
0.628 0.372 0.000
M24.58 Contracture of joint (Other)
0.628 0.372 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.628 0.372 0.000
M24.53 Contracture of joint (Forearm)
0.628 0.372 0.000
M24.52 Contracture of joint (Upper arm)
0.628 0.372 0.000
M24.51 Contracture of joint (Shoulder region)
0.628 0.372 0.000
M24.50 Contracture of joint (Multiple sites)
0.628 0.372 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.628 0.372 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.628 0.372 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.628 0.372 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.628 0.372 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.628 0.372 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.628 0.372 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.628 0.372 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.628 0.372 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.628 0.372 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.627 0.372 0.000
S80 Superficial injury of lower leg
0.627 0.373 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.627 0.373 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.627 0.373 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.625 0.375 0.000
L04 Acute lymphadenitis
0.625 0.375 0.000
L01 Impetigo
0.625 0.375 0.000
L00 Staphylococcal scalded skin syndrome
0.625 0.375 0.000
T45.0 Antiallergic and antiemetic drugs
0.625 0.375 0.000
W06.0 Home
0.625 0.375 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.624 0.376 0.000
M24.24 Disorder of ligament (Hand)
0.623 0.377 0.000
T43.9 Psychotropic drug, unspecified
0.623 0.377 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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