TreeWAS – Variant ID: rs7711337

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I49.0 Ventricular fibrillation and flutter	0.080	0.920	0.000
I49 Other cardiac arrhythmias	0.077	0.923	0.000
I49.3 Ventricular premature depolarisation	0.076	0.924	0.000
I49.1 Atrial premature depolarisation	0.073	0.927	0.000
I49.5 Sick sinus syndrome	0.068	0.932	0.000
I49.9 Cardiac arrhythmia, unspecified	0.068	0.932	0.000
I72.3 Aneurysm of iliac artery	0.057	0.943	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.057	0.943	0.000
I72 Other aneurysm	0.056	0.944	0.000
I49.2 Junctional premature depolarisation	0.055	0.944	0.000
I77 Other disorders of arteries and arterioles	0.055	0.945	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.054	0.946	0.000
I72.4 Aneurysm of artery of lower extremity	0.053	0.947	0.000
I70 Atherosclerosis	0.050	0.950	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.048	0.952	0.000
I77.6 Arteritis, unspecified	0.047	0.953	0.000
I77.8 Other specified disorders of arteries and arterioles	0.047	0.953	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.046	0.954	0.000
I78 Diseases of capillaries	0.042	0.958	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.040	0.960	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.040	0.960	0.000
I72.8 Aneurysm of other specified arteries	0.040	0.960	0.000
I77.5 Necrosis of artery	0.040	0.960	0.000
I77.4 Coeliac artery compression syndrome	0.040	0.960	0.000
I77.3 Arterial fibromuscular dysplasia	0.040	0.960	0.000
I72.0 Aneurysm of carotid artery	0.040	0.960	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.039	0.961	0.000
I72.2 Aneurysm of renal artery	0.039	0.961	0.000
I74 Arterial embolism and thrombosis	0.039	0.961	0.000
I74.5 Embolism and thrombosis of iliac artery	0.037	0.963	0.000
I71 Aortic aneurysm and dissection	0.037	0.963	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.036	0.964	0.000
I70.0 Atherosclerosis of aorta	0.036	0.964	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.036	0.964	0.000
I70.9 Generalised and unspecified atherosclerosis	0.035	0.965	0.000
I77.0 Arteriovenous fistula, acquired	0.035	0.965	0.000
I70.1 Atherosclerosis of renal artery	0.035	0.965	0.000
I70.8 Atherosclerosis of other arteries	0.035	0.965	0.000
I72.1 Aneurysm of artery of upper extremity	0.034	0.966	0.000
I77.2 Rupture of artery	0.032	0.967	0.000
I78.9 Disease of capillaries, unspecified	0.031	0.968	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.031	0.969	0.000
I78.1 Naevus, nonneoplastic	0.031	0.969	0.000
I78.8 Other diseases of capillaries	0.031	0.969	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.031	0.969	0.000
I77.1 Stricture of artery	0.031	0.969	0.000
I73 Other peripheral vascular diseases	0.031	0.969	0.000
I74.8 Embolism and thrombosis of other arteries	0.029	0.971	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.028	0.972	0.000
I72.9 Aneurysm of unspecified site	0.028	0.972	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.028	0.972	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.028	0.972	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.027	0.973	0.000
I73.8 Other specified peripheral vascular diseases	0.027	0.973	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.026	0.973	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.026	0.973	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.026	0.974	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.026	0.974	0.000
I79.1 Aortitis in diseases classified elsewhere	0.026	0.974	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.026	0.974	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.026	0.974	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.025	0.974	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.025	0.975	0.000
I49.8 Other specified cardiac arrhythmias	0.025	0.975	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.025	0.975	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.025	0.975	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.025	0.975	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.024	0.975	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.024	0.976	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.023	0.977	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.977	0.023
I74.9 Embolism and thrombosis of unspecified artery	0.022	0.978	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.022	0.978	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.978	0.022
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.021	0.979	0.000
T92 Sequelae of injuries of upper limb	0.000	0.979	0.021
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.981	0.019
I71.3 Abdominal aortic aneurysm, ruptured	0.019	0.981	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.982	0.018
I73.9 Peripheral vascular disease, unspecified	0.017	0.983	0.000
S30.0 Contusion of lower back and pelvis	0.000	0.983	0.017
T92.0 Sequelae of open wound of upper limb	0.000	0.984	0.016
I71.0 Dissection of aorta [any part]	0.016	0.984	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.984	0.016
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.015	0.985	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.985	0.015
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.985	0.015
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.985	0.015
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.986	0.014
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.987	0.013
M22.8 Other disorders of patella	0.013	0.987	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.012	0.988	0.000
Y52.1 Calcium-channel blockers	0.012	0.988	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.012	0.988	0.000
I49.4 Other and unspecified premature depolarisation	0.011	0.988	0.001
Y52 Agents primarily affecting the cardiovascular system	0.012	0.988	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.011	0.989	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.989	0.011
S42.20 Fracture of upper end of humerus (closed)	0.000	0.989	0.011
A08.4 Viral intestinal infection, unspecified	0.000	0.989	0.011
T92.1 Sequelae of fracture of arm	0.000	0.990	0.010
C18.4 Transverse colon	0.000	0.990	0.010
S30.2 Contusion of external genital organs	0.000	0.990	0.010
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.990	0.010
H61.0 Perichondritis of external ear	0.000	0.990	0.010
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.990	0.010
Y52.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.990	0.010
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.009	0.991	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.991	0.009
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.991	0.009
Y52.7 Peripheral vasodilators	0.009	0.991	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.009	0.991	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.009	0.991	0.000
R80 Isolated proteinuria	0.000	0.992	0.008
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
S42.2 Fracture of upper end of humerus	0.000	0.992	0.008
S42.00 Fracture of clavicle (closed)	0.000	0.992	0.008
N75.1 Abscess of Bartholin's gland	0.007	0.993	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.993	0.007
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.993	0.007
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.993	0.007
T82.1 Mechanical complication of cardiac electronic device	0.000	0.993	0.007
N75.0 Cyst of Bartholin's gland	0.007	0.993	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.993	0.006
O26.8 Other specified pregnancy-related conditions	0.000	0.993	0.007
S42.0 Fracture of clavicle	0.000	0.994	0.006
N75 Diseases of Bartholin's gland	0.006	0.994	0.000
K25.7 Chronic without haemorrhage or perforation	0.006	0.994	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.994	0.006
S42.21 Fracture of upper end of humerus (open)	0.000	0.994	0.006
Z43.2 Attention to ileostomy	0.000	0.994	0.006
S42 Fracture of shoulder and upper arm	0.000	0.995	0.005
N80.8 Other endometriosis	0.000	0.995	0.005
Z43 Attention to artificial openings	0.000	0.995	0.005
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.995	0.005
N75.8 Other diseases of Bartholin's gland	0.005	0.995	0.000
Z43.3 Attention to colostomy	0.000	0.995	0.005
A08 Viral and other specified intestinal infections	0.000	0.995	0.005
I73.0 Raynaud's syndrome	0.005	0.995	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.995	0.005
I31.3 Pericardial effusion (noninflammatory)	0.005	0.995	0.000
A08.3 Other viral enteritis	0.000	0.995	0.005
S42.01 Fracture of clavicle (open)	0.000	0.995	0.005
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.995	0.005
S30.1 Contusion of abdominal wall	0.000	0.995	0.004
Z43.5 Attention to cyctostomy	0.000	0.995	0.005
N75.9 Disease of Bartholin's gland, unspecified	0.005	0.995	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.995	0.004
E83.4 Disorders of magnesium metabolism	0.000	0.995	0.005
Z43.0 Attention to tracheostomy	0.000	0.995	0.005
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.996	0.004
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.996	0.004
Z43.9 Attention to unspecified artificial opening	0.000	0.996	0.004
Z43.7 Attention to artificial vagina	0.000	0.996	0.004
H61 Other disorders of external ear	0.000	0.996	0.004
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.996	0.004
A08.0 Rotaviral enteritis	0.000	0.996	0.004
G03.9 Meningitis, unspecified	0.000	0.996	0.004
A08.2 Adenoviral enteritis	0.000	0.996	0.004
H21.8 Other specified disorders of iris and ciliary body	0.004	0.996	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.996	0.004
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.996	0.004
A08.5 Other specified intestinal infections	0.000	0.996	0.004
Z93.2 Ileostomy status	0.000	0.996	0.004
K04.5 Chronic apical periodontitis	0.000	0.996	0.004
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.996	0.004
I31 Other diseases of pericardium	0.003	0.997	0.000
H61.2 Impacted cerumen	0.000	0.997	0.003
Z43.8 Attention to other artificial openings	0.000	0.997	0.003
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.997	0.003
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.997	0.003
S42.1 Fracture of scapula	0.000	0.997	0.003
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.997	0.003
H66.9 Otitis media, unspecified	0.000	0.997	0.003
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.997	0.003
W08.0 Home	0.000	0.997	0.003
H61.1 Non-infective disorders of pinna	0.000	0.997	0.003
I31.9 Disease of pericardium, unspecified	0.003	0.997	0.000
O64.1 Obstructed labour due to breech presentation	0.000	0.997	0.003
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
K05.3 Chronic periodontitis	0.000	0.997	0.003
S42.3 Fracture of shaft of humerus	0.000	0.997	0.003
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.997	0.003
H61.9 Disorder of external ear, unspecified	0.000	0.997	0.003
I31.0 Chronic adhesive pericarditis	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.997	0.003
K04.8 Radicular cyst	0.000	0.997	0.003
I31.8 Other specified diseases of pericardium	0.003	0.997	0.000
I31.2 Haemopericardium, not elsewhere classified	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.000	0.997	0.003
I38 Endocarditis, valve unspecified	0.003	0.997	0.000
K56.7 Ileus, unspecified	0.000	0.997	0.003
M13.00 Polyarthritis, unspecified (Multiple sites)	0.003	0.997	0.000
D10.1 Tongue	0.000	0.997	0.003
Z43.1 Attention to gastrostomy	0.000	0.997	0.003
M43.02 Spondylolysis (Cervical region)	0.000	0.997	0.003
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.997	0.002
I31.1 Chronic constrictive pericarditis	0.002	0.997	0.000
I30.1 Infective pericarditis	0.003	0.997	0.000
S42.11 Fracture of scapula (open)	0.000	0.997	0.002
M79.63 Pain in limb (Forearm)	0.000	0.998	0.002
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.002
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
Y83.3 Surgical operation with formation of external stoma	0.000	0.998	0.002
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
Z93.3 Colostomy status	0.000	0.998	0.002
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.000	0.998	0.002
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
R81 Glycosuria	0.000	0.998	0.002
J38.4 Oedema of larynx	0.000	0.998	0.002
G03 Meningitis due to other and unspecified causes	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
D43.0 Brain, supratentorial	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.002	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.998	0.002
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
W45.6 Industrial and construction area	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.001
N83.3 Acquired atrophy of ovary and Fallopian tube	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
I30-I52 Other forms of heart disease	0.002	0.998	0.000
G03.8 Meningitis due to other specified causes	0.000	0.998	0.002
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.998	0.002
G03.1 Chronic meningitis	0.000	0.998	0.002
G03.0 Nonpyogenic meningitis	0.000	0.998	0.002
O30.0 Twin pregnancy	0.002	0.998	0.000
H66 Suppurative and unspecified otitis media	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
S72.80 Fractures of other parts of femur (closed)	0.000	0.998	0.002
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
D39.0 Uterus	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
M06.0 Seronegative rheumatoid arthritis	0.000	0.998	0.002
O26.0 Excessive weight gain in pregnancy	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.998	0.002
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.998	0.000
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.000	0.998	0.002
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
O26.5 Maternal hypotension syndrome	0.000	0.998	0.001
O26.4 Herpes gestationis	0.000	0.998	0.001
O26.1 Low weight gain in pregnancy	0.000	0.998	0.001
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
O26.2 Pregnancy care of habitual aborter	0.000	0.998	0.002
M19.1 Posttraumatic arthrosis of other joints	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
W29.9 Unspecified place	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.001
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
D40.1 Testis	0.001	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.998	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.001	0.998	0.000
I48 Atrial fibrillation and flutter	0.001	0.998	0.000
I41 Myocarditis in diseases classified elsewhere	0.001	0.998	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I32 Pericarditis in diseases classified elsewhere	0.001	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.001	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.998	0.001
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.001
E83.2 Disorders of zinc metabolism	0.000	0.998	0.001
E83.0 Disorders of copper metabolism	0.000	0.998	0.001
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
S72.8 Fractures of other parts of femur	0.000	0.998	0.001
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.001	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.001	0.998	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.001	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.000	0.999	0.001
D46 Myelodysplastic syndromes	0.001	0.999	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.999	0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.999	0.001
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.999	0.001
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.999	0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.999	0.001
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.999	0.001
D40.9 Male genital organ, unspecified	0.001	0.999	0.000
D43.9 Central nervous system, unspecified	0.001	0.999	0.000
D43.7 Other parts of central nervous system	0.001	0.999	0.000
D43.3 Cranial nerves	0.001	0.999	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.001	0.999	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.999	0.001
K04 Diseases of pulp and periapical tissues	0.000	0.999	0.001
O21 Excessive vomiting in pregnancy	0.001	0.999	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.001	0.999	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.001	0.999	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.001	0.999	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.001	0.999	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.999	0.001
S42.10 Fracture of scapula (closed)	0.000	0.999	0.001
D47.1 Chronic myeloproliferative disease	0.001	0.999	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.001	0.999	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.999	0.001
M88.9 Paget's disease of bone, unspecified	0.000	0.999	0.001
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.000	0.999	0.001
D40.7 Other male genital organs	0.001	0.999	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.999	0.001
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.999	0.001
D45 Polycythaemia vera	0.001	0.999	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
D47.4 Osteomyelofibrosis	0.001	0.999	0.000
J69.8 Pneumonitis due to other solids and liquids	0.001	0.999	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.999	0.001
D14.0 Middle ear, nasal cavity and accessory sinuses	0.001	0.999	0.000
D39.9 Female genital organ, unspecified	0.001	0.999	0.000
D39.2 Placenta	0.001	0.999	0.000
D39.1 Ovary	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.000	0.999	0.001
I32.8 Pericarditis in other diseases classified elsewhere	0.001	0.999	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.001	0.999	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.001	0.999	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.001	0.999	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.001	0.999	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.001	0.999	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.001	0.999	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.001	0.999	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.001	0.999	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.001	0.999	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.001	0.999	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.001	0.999	0.000
I48.4 Atypical atrial flutter	0.001	0.999	0.000
I48.3 Typical atrial flutter	0.001	0.999	0.000
I48.2 Chronic atrial fibrillation	0.001	0.999	0.000
I48.1 Persistent atrial fibrillation	0.001	0.999	0.000
I48.0 Paroxysmal atrial fibrillation	0.001	0.999	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.001	0.999	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.001	0.999	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.999	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.001	0.999	0.000
I40 Acute myocarditis	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.999	0.001
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.001	0.999	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.001	0.999	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.001	0.999	0.000
O92.1 Cracked nipple associated with childbirth	0.001	0.999	0.000
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.999	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.001	0.999	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.999	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.999	0.000
O21.8 Other vomiting complicating pregnancy	0.001	0.999	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.999	0.001
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.999	0.001
W08 Fall involving other furniture	0.000	0.999	0.001
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
D16.4 Bones of skull and face	0.001	0.999	0.000
D44.8 Pluriglandular involvement	0.001	0.999	0.000
H10.9 Conjunctivitis, unspecified	0.001	0.999	0.000
K04.3 Abnormal hard tissue formation in pulp	0.000	0.999	0.001
K04.2 Pulp degeneration	0.000	0.999	0.001
K04.1 Necrosis of pulp	0.000	0.999	0.001
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.999	0.001
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.999	0.001
D14.1 Larynx	0.001	0.999	0.000
D46.4 Refractory anaemia, unspecified	0.001	0.999	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.999	0.000
S72 Fracture of femur	0.000	0.999	0.001
F99-F99 Unspecified mental disorder	0.000	0.999	0.001
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.999	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.999	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.999	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.999	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.999	0.001
S72.31 Fracture of shaft of femur (open)	0.000	0.999	0.001
D46.1 Refractory anaemia with sideroblasts	0.001	0.999	0.000
G06.2 Extradural and subdural abscess, unspecified	0.001	0.999	0.000
I35.1 Aortic (valve) insufficiency	0.001	0.999	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
M13.0 Polyarthritis, unspecified	0.001	0.999	0.000
O64.5 Obstructed labour due to compound presentation	0.000	0.999	0.001
O64.4 Obstructed labour due to shoulder presentation	0.000	0.999	0.001
O64.3 Obstructed labour due to brow presentation	0.000	0.999	0.001
O92.7 Other and unspecified disorders of lactation	0.001	0.999	0.000
O92.6 Galactorrhoea	0.001	0.999	0.000
O92.5 Suppressed lactation	0.001	0.999	0.000
O92.4 Hypogalactia	0.001	0.999	0.000
O92.3 Agalactia	0.001	0.999	0.000
O92.0 Retracted nipple associated with childbirth	0.001	0.999	0.000
R85.5 Abnormal microbiological findings	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
D39.7 Other female genital organs	0.001	0.999	0.000
H66.0 Acute suppurative otitis media	0.000	0.999	0.001
I63.8 Other cerebral infarction	0.001	0.999	0.000
S61.1 Open wound of finger(s) with damage to nail	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.000	0.999	0.001
W45.8 Other specified place	0.001	0.999	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.999	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.001	0.999	0.000
O28 Abnormal findings on antenatal screening of mother	0.001	0.999	0.000
D43.4 Spinal cord	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.999	0.000
D47.2 Monoclonal gammopathy	0.001	0.999	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.999	0.000
D48.4 Peritoneum	0.001	0.999	0.000
I33 Acute and subacute endocarditis	0.001	0.999	0.000
W45 Foreign body or object entering through skin	0.001	0.999	0.000
S62.61 Fracture of other finger (open)	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
E83.5 Disorders of calcium metabolism	0.000	0.999	0.001
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.999	0.001
I40.8 Other acute myocarditis	0.001	0.999	0.000
I40.1 Isolated myocarditis	0.001	0.999	0.000
J38.6 Stenosis of larynx	0.000	0.999	0.001
Q05.9 Spina bifida, unspecified	0.000	0.999	0.001
S80.0 Contusion of knee	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.000	0.999	0.001
W13.9 Unspecified place	0.001	0.999	0.000
W45.4 Street and highway	0.001	0.999	0.000
D43.1 Brain, infratentorial	0.001	0.999	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.001	0.999	0.000
I33.9 Acute endocarditis, unspecified	0.001	0.999	0.000
N90.5 Atrophy of vulva	0.000	0.999	0.001
O64.2 Obstructed labour due to face presentation	0.000	0.999	0.001
W08.8 Other specified place	0.000	0.999	0.001
W08.7 Farm	0.000	0.999	0.001
W08.6 Industrial and construction area	0.000	0.999	0.001
W08.5 Trade and service area	0.000	0.999	0.001
W08.4 Street and highway	0.000	0.999	0.001
W08.3 Sports and athletics area	0.000	0.999	0.001
W08.2 School, other institution and public administrative area	0.000	0.999	0.001
W08.1 Residential institution	0.000	0.999	0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.001	0.999	0.000
I36 Nonrheumatic tricuspid valve disorders	0.001	0.999	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.001	0.999	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.999	0.001
D38.0 Larynx	0.001	0.999	0.000
K04.0 Pulpitis	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations