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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77330364
log Bayes Factor = 16.5387
Chromosome 3   position 79,373,033  (GRCh37) Explore rs77330364 on Ensembl!
Variant rs77330364 is part of Cluster X0257

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.998 0.002 0.000
K55-K64 Other diseases of intestines
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.986 0.014 0.000
Z87 Personal history of other diseases and conditions
0.982 0.018 0.000
M15-M19 Arthrosis
0.981 0.019 0.000
N39 Other disorders of urinary system
0.977 0.023 0.000
N10-N16 Renal tubulo-interstitial diseases
0.977 0.023 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.974 0.026 0.000
K59 Other functional intestinal disorders
0.972 0.028 0.000
M19 Other arthrosis
0.969 0.031 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.969 0.031 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.966 0.034 0.000
R30-R39 Symptoms and signs involving the urinary system
0.964 0.036 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
M19.9 Arthrosis, unspecified
0.957 0.043 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.956 0.044 0.000
N13 Obstructive and reflux uropathy
0.956 0.044 0.000
N39.0 Urinary tract infection, site not specified
0.954 0.046 0.000
K59.0 Constipation
0.951 0.049 0.000
Z53.0 Procedure not carried out because of contraindication
0.946 0.054 0.000
N17-N19 Renal failure
0.945 0.055 0.000
Z50 Care involving use of rehabilitation procedures
0.939 0.061 0.000
Chapter IX Diseases of the circulatory system
0.939 0.061 0.000
N35 Urethral stricture
0.934 0.066 0.000
K50-K52 Noninfective enteritis and colitis
0.933 0.067 0.000
Chapter VII Diseases of the eye and adnexa
0.933 0.067 0.000
Z93 Artificial opening status
0.933 0.067 0.000
N30 Cystitis
0.930 0.070 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.928 0.072 0.000
R32 Unspecified urinary incontinence
0.928 0.072 0.000
R33 Retention of urine
0.925 0.075 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.924 0.076 0.000
Z45 Adjustment and management of implanted device
0.915 0.085 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.914 0.086 0.000
R11 Nausea and vomiting
0.912 0.088 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.908 0.092 0.000
S50-S59 Injuries to the elbow and forearm
0.908 0.092 0.000
Chapter V Mental and behavioural disorders
0.902 0.098 0.000
H30-H36 Disorders of choroid and retina
0.895 0.105 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.892 0.108 0.000
K61 Abscess of anal and rectal regions
0.890 0.110 0.000
N35.9 Urethral stricture, unspecified
0.889 0.111 0.000
K60 Fissure and fistula of anal and rectal regions
0.887 0.113 0.000
M06 Other rheumatoid arthritis
0.886 0.114 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.884 0.116 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.884 0.116 0.000
Z87.1 Personal history of diseases of the digestive system
0.884 0.116 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.882 0.118 0.000
N17 Acute renal failure
0.877 0.123 0.000
K70-K77 Diseases of liver
0.877 0.123 0.000
N13.3 Other and unspecified hydronephrosis
0.876 0.124 0.000
M20-M25 Other joint disorders
0.874 0.126 0.000
K35-K38 Diseases of appendix
0.872 0.128 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.871 0.129 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.870 0.130 0.000
H43-H45 Disorders of vitreous body and globe
0.868 0.131 0.000
E65-E68 Obesity and other hyperalimentation
0.867 0.133 0.000
Z46 Fitting and adjustment of other devices
0.863 0.137 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.858 0.142 0.000
H33 Retinal detachments and breaks
0.857 0.143 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.854 0.146 0.000
T81 Complications of procedures, not elsewhere classified
0.854 0.146 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.854 0.146 0.000
Z51 Other medical care
0.845 0.155 0.000
N39.4 Other specified urinary incontinence
0.845 0.155 0.000
K55 Vascular disorders of intestine
0.844 0.156 0.000
R42 Dizziness and giddiness
0.844 0.156 0.000
S52 Fracture of forearm
0.842 0.158 0.000
I60-I69 Cerebrovascular diseases
0.841 0.159 0.000
N00-N08 Glomerular diseases
0.840 0.160 0.000
K50 Crohn's disease [regional enteritis]
0.839 0.161 0.000
K51 Ulcerative colitis
0.835 0.165 0.000
Z96 Presence of other functional implants
0.834 0.166 0.000
E66 Obesity
0.833 0.167 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.833 0.167 0.000
R18 Ascites
0.829 0.171 0.000
N17.9 Acute renal failure, unspecified
0.829 0.171 0.000
Chapter VIII Diseases of the ear and mastoid process
0.828 0.172 0.000
D50-D53 Nutritional anaemias
0.827 0.173 0.000
Z86 Personal history of certain other diseases
0.827 0.173 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.824 0.176 0.000
N30.2 Other chronic cystitis
0.823 0.177 0.000
H43 Disorders of vitreous body
0.823 0.177 0.000
M50-M54 Other dorsopathies
0.820 0.180 0.000
K74 Fibrosis and cirrhosis of liver
0.818 0.182 0.000
N20-N23 Urolithiasis
0.815 0.185 0.000
Z47 Other orthopaedic follow-up care
0.813 0.187 0.000
M06.0 Seronegative rheumatoid arthritis
0.813 0.187 0.000
I10-I15 Hypertensive diseases
0.812 0.188 0.000
Z50.8 Care involving use of rehabilitation procedures
0.812 0.188 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.812 0.188 0.000
S52.5 Fracture of lower end of radius
0.810 0.190 0.000
K63 Other diseases of intestine
0.809 0.191 0.000
M25 Other joint disorders, not elsewhere classified
0.809 0.191 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.808 0.192 0.000
M80-M85 Disorders of bone density and structure
0.807 0.193 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.807 0.193 0.000
M16 Coxarthrosis [arthrosis of hip]
0.806 0.194 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.805 0.195 0.000
K57 Diverticular disease of intestine
0.805 0.195 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.804 0.195 0.000
N36 Other disorders of urethra
0.804 0.196 0.000
I05-I09 Chronic rheumatic heart diseases
0.804 0.196 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.801 0.199 0.000
Z50.1 Other physical therapy
0.800 0.200 0.000
D50 Iron deficiency anaemia
0.800 0.200 0.000
Z93.1 Gastrostomy status
0.799 0.201 0.000
S80-S89 Injuries to the knee and lower leg
0.798 0.202 0.000
M35 Other systemic involvement of connective tissue
0.798 0.202 0.000
M07 Psoriatic and enteropathic arthropathies
0.796 0.204 0.000
Z93.3 Colostomy status
0.793 0.207 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.793 0.207 0.000
Chapter I Certain infectious and parasitic diseases
0.792 0.208 0.000
K60.1 Chronic anal fissure
0.792 0.208 0.000
Z97 Presence of other devices
0.791 0.208 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.791 0.209 0.000
T87 Complications peculiar to reattachment and amputation
0.789 0.211 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.789 0.211 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.789 0.211 0.000
E66.9 Obesity, unspecified
0.789 0.211 0.000
I84 Haemorrhoids
0.789 0.211 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.788 0.212 0.000
S52.50 Fracture of lower end of radius (closed)
0.787 0.213 0.000
I80 Phlebitis and thrombophlebitis
0.785 0.215 0.000
Z87.8 Personal history of other specified conditions
0.783 0.217 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.783 0.217 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.782 0.218 0.000
Z53.8 Procedure not carried out for other reasons
0.781 0.219 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
I84.9 Unspecified haemorrhoids without complication
0.780 0.220 0.000
D50.9 Iron deficiency anaemia, unspecified
0.780 0.220 0.000
M13 Other arthritis
0.780 0.220 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.779 0.221 0.000
K35 Acute appendicitis
0.779 0.221 0.000
S90-S99 Injuries to the ankle and foot
0.778 0.222 0.000
M45-M49 Spondylopathies
0.777 0.223 0.000
Chapter XXII Codes for special purposes
0.776 0.224 0.000
Z93.2 Ileostomy status
0.775 0.225 0.000
M70-M79 Other soft tissue disorders
0.773 0.227 0.000
M60-M63 Disorders of muscles
0.767 0.232 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.766 0.234 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.765 0.235 0.000
Z46.6 Fitting and adjustment of urinary device
0.765 0.235 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.765 0.235 0.000
H43.1 Vitreous haemorrhage
0.764 0.236 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.763 0.237 0.000
N25-N29 Other disorders of kidney and ureter
0.762 0.238 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.760 0.240 0.000
N18 Chronic renal failure
0.757 0.243 0.000
K61.0 Anal abscess
0.756 0.244 0.000
S40-S49 Injuries to the shoulder and upper arm
0.756 0.244 0.000
M19.0 Primary arthrosis of other joints
0.755 0.245 0.000
M19.94 Arthrosis, unspecified (Hand)
0.755 0.245 0.000
H33.0 Retinal detachment with retinal break
0.755 0.245 0.000
M40-M43 Deforming dorsopathies
0.749 0.251 0.000
N30.1 Interstitial cystitis (chronic)
0.747 0.253 0.000
K11 Diseases of salivary glands
0.746 0.254 0.000
K61.3 Ischiorectal abscess
0.746 0.254 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
Z86.7 Personal history of diseases of the circulatory system
0.744 0.256 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.743 0.257 0.000
N39.8 Other specified disorders of urinary system
0.743 0.257 0.000
K50.9 Crohn's disease, unspecified
0.743 0.257 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.743 0.257 0.000
N03 Chronic nephritic syndrome
0.742 0.258 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.742 0.258 0.000
Z45.1 Adjustment and management of infusion pump
0.739 0.261 0.000
K75 Other inflammatory liver diseases
0.738 0.262 0.000
Z91.6 Personal history of other physical trauma
0.737 0.263 0.000
K55.2 Angiodysplasia of colon
0.735 0.264 0.000
R50-R69 General symptoms and signs
0.735 0.265 0.000
K59.8 Other specified functional intestinal disorders
0.734 0.266 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.734 0.266 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.733 0.267 0.000
N30.9 Cystitis, unspecified
0.733 0.267 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.733 0.267 0.000
H33.4 Traction detachment of retina
0.732 0.268 0.000
Z42 Follow-up care involving plastic surgery
0.732 0.268 0.000
S70-S79 Injuries to the hip and thigh
0.732 0.268 0.000
N30.3 Trigonitis
0.732 0.268 0.000
Z94 Transplanted organ and tissue status
0.731 0.269 0.000
E10-E14 Diabetes mellitus
0.731 0.269 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.730 0.270 0.000
Z93.5 Cystostomy status
0.730 0.270 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.730 0.270 0.000
S00-S09 Injuries to the head
0.730 0.270 0.000
R16.1 Splenomegaly, not elsewhere classified
0.729 0.271 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.729 0.271 0.000
I63 Cerebral infarction
0.729 0.271 0.000
Chapter II Neoplasms
0.728 0.272 0.000
I85 Oesophageal varices
0.728 0.272 0.000
K09 Cysts of oral region, not elsewhere classified
0.728 0.272 0.000
K90-K93 Other diseases of the digestive system
0.727 0.273 0.000
Chapter XX External causes of morbidity and mortality
0.727 0.273 0.000
N60-N64 Disorders of breast
0.726 0.274 0.000
H35 Other retinal disorders
0.725 0.275 0.000
M19.1 Posttraumatic arthrosis of other joints
0.724 0.276 0.000
T93 Sequelae of injuries of lower limb
0.724 0.276 0.000
R30 Pain associated with micturition
0.724 0.276 0.000
N19 Unspecified renal failure
0.723 0.277 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.723 0.277 0.000
N13.8 Other obstructive and reflux uropathy
0.722 0.278 0.000
Z29 Need for other prophylactic measures
0.722 0.278 0.000
M16.1 Other primary coxarthrosis
0.720 0.280 0.000
M54 Dorsalgia
0.720 0.280 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.719 0.281 0.000
I81 Portal vein thrombosis
0.718 0.282 0.000
F80-F89 Disorders of psychological development
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.717 0.283 0.000
Z54 Convalescence
0.716 0.284 0.000
Z52 Donors of organs and tissues
0.716 0.284 0.000
Z49 Care involving dialysis
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.715 0.285 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.714 0.285 0.000
Z51.5 Palliative care
0.715 0.285 0.000
K14 Diseases of tongue
0.714 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.713 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.286 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.713 0.287 0.000
H33.2 Serous retinal detachment
0.711 0.289 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.710 0.290 0.000
K10 Other diseases of jaws
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.709 0.291 0.000
H43.8 Other disorders of vitreous body
0.709 0.291 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.709 0.291 0.000
E20-E35 Disorders of other endocrine glands
0.709 0.291 0.000
Z43 Attention to artificial openings
0.708 0.292 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.708 0.292 0.000
N20 Calculus of kidney and ureter
0.707 0.293 0.000
K63.5 Polyp of colon
0.707 0.293 0.000
Z89 Acquired absence of limb
0.707 0.293 0.000
Z84 Family history of other conditions
0.707 0.293 0.000
Z81 Family history of mental and behavioural disorders
0.707 0.293 0.000
E66.8 Other obesity
0.706 0.294 0.000
M25.4 Effusion of joint
0.705 0.295 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.704 0.296 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.704 0.296 0.000
I12 Hypertensive renal disease
0.704 0.296 0.000
M15 Polyarthrosis
0.703 0.297 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.702 0.298 0.000
M10 Gout
0.702 0.298 0.000
M06.9 Rheumatoid arthritis, unspecified
0.702 0.298 0.000
Z36 Antenatal screening
0.701 0.299 0.000
K56.2 Volvulus
0.701 0.299 0.000
N39.2 Orthostatic proteinuria, unspecified
0.700 0.299 0.000
N39.1 Persistent proteinuria, unspecified
0.700 0.299 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.700 0.299 0.000
N15 Other renal tubulo-interstitial diseases
0.700 0.299 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.700 0.299 0.000
N11 Chronic tubulo-interstitial nephritis
0.700 0.299 0.000
N10 Acute tubulo-interstitial nephritis
0.700 0.299 0.000
Z96.8 Presence of other specified functional implants
0.699 0.301 0.000
N40-N51 Diseases of male genital organs
0.699 0.301 0.000
T51 Toxic effect of alcohol
0.699 0.301 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.698 0.302 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.698 0.302 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.698 0.302 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.698 0.302 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.698 0.302 0.000
M19.98 Arthrosis, unspecified (Other)
0.698 0.302 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.698 0.302 0.000
K59.9 Functional intestinal disorder, unspecified
0.697 0.303 0.000
K59.4 Anal spasm
0.697 0.303 0.000
K59.3 Megacolon, not elsewhere classified
0.697 0.303 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.697 0.303 0.000
K59.1 Functional diarrhoea
0.697 0.303 0.000
I26 Pulmonary embolism
0.697 0.303 0.000
S82 Fracture of lower leg, including ankle
0.696 0.304 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.696 0.304 0.000
I86 Varicose veins of other sites
0.695 0.305 0.000
M19.8 Other specified arthrosis
0.695 0.305 0.000
M19.2 Other secondary arthrosis
0.695 0.305 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.695 0.305 0.000
K65-K67 Diseases of peritoneum
0.693 0.307 0.000
E00-E07 Disorders of thyroid gland
0.692 0.308 0.000
K74.0 Hepatic fibrosis
0.691 0.309 0.000
R36 Urethral discharge
0.691 0.309 0.000
R34 Anuria and oliguria
0.691 0.309 0.000
K74.3 Primary biliary cirrhosis
0.689 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.688 0.312 0.000
M12 Other specific arthropathies
0.688 0.312 0.000
M11 Other crystal arthropathies
0.688 0.312 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.688 0.312 0.000
M08 Juvenile arthritis
0.688 0.312 0.000
M05 Seropositive rheumatoid arthritis
0.688 0.312 0.000
M35.0 Sicca syndrome [Sjogren]
0.688 0.312 0.000
I83 Varicose veins of lower extremities
0.688 0.312 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.687 0.313 0.000
M86-M90 Other osteopathies
0.687 0.313 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.686 0.314 0.000
I08 Multiple valve diseases
0.686 0.314 0.000
N39.9 Disorder of urinary system, unspecified
0.686 0.314 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.686 0.314 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.686 0.314 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.685 0.314 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.685 0.315 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.685 0.315 0.000
N13.6 Pyonephrosis
0.685 0.315 0.000
N13.4 Hydroureter
0.685 0.315 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.685 0.315 0.000
M35.3 Polymyalgia rheumatica
0.685 0.315 0.000
H10-H13 Disorders of conjunctiva
0.683 0.317 0.000
S60-S69 Injuries to the wrist and hand
0.682 0.317 0.000
K74.6 Other and unspecified cirrhosis of liver
0.682 0.318 0.000
T81.9 Unspecified complication of procedure
0.682 0.318 0.000
T66-T78 Other and unspecified effects of external causes
0.681 0.318 0.000
R40 Somnolence, stupor and coma
0.681 0.319 0.000
Z40 Prophylactic surgery
0.681 0.319 0.000
M16.0 Primary coxarthrosis, bilateral
0.681 0.319 0.000
H90-H95 Other disorders of ear
0.680 0.320 0.000
K72 Hepatic failure, not elsewhere classified
0.679 0.321 0.000
M07.3 Other psoriatic arthropathies
0.679 0.321 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.678 0.322 0.000
Z47.8 Other specified orthopaedic follow-up care
0.678 0.322 0.000
K08 Other disorders of teeth and supporting structures
0.677 0.323 0.000
K13 Other diseases of lip and oral mucosa
0.676 0.324 0.000
F30-F39 Mood [affective] disorders
0.674 0.326 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.674 0.326 0.000
Z50.6 Orthoptic training
0.673 0.326 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.673 0.326 0.000
Z50.3 Drug rehabilitation
0.673 0.326 0.000
I00-I02 Acute rheumatic fever
0.673 0.326 0.000
N99-N99 Other disorders of the genitourinary system
0.673 0.327 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.673 0.327 0.000
Z50.2 Alcohol rehabilitation
0.673 0.327 0.000
N03.9 Unspecified
0.673 0.327 0.000
K60.2 Anal fissure, unspecified
0.671 0.329 0.000
Z83 Family history of other specific disorders
0.671 0.329 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.671 0.329 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.670 0.329 0.000
N35.8 Other urethral stricture
0.670 0.330 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.670 0.330 0.000
N35.0 Posttraumatic urethral stricture
0.670 0.330 0.000
K35.9 Acute appendicitis, unspecified
0.670 0.330 0.000
K51.9 Ulcerative colitis, unspecified
0.669 0.331 0.000
H55-H59 Other disorders of eye and adnexa
0.669 0.331 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.669 0.331 0.000
Z48 Other surgical follow-up care
0.669 0.331 0.000
Z93.9 Artificial opening status, unspecified
0.669 0.331 0.000
Z93.8 Other artificial opening status
0.669 0.331 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.669 0.331 0.000
Z93.0 Tracheostomy status
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.668 0.332 0.000
N30.4 Irradiation cystitis
0.667 0.333 0.000
N30.0 Acute cystitis
0.667 0.333 0.000
N36.8 Other specified disorders of urethra
0.665 0.335 0.000
M25.7 Osteophyte
0.665 0.335 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.664 0.335 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.664 0.336 0.000
Z86.0 Personal history of other neoplasms
0.663 0.337 0.000
K50.1 Crohn's disease of large intestine
0.662 0.338 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.661 0.339 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.660 0.339 0.000
M22 Disorders of patella
0.660 0.340 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.659 0.341 0.000
T92 Sequelae of injuries of upper limb
0.659 0.341 0.000
R12 Heartburn
0.656 0.344 0.000
Z34 Supervision of normal pregnancy
0.656 0.344 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.656 0.344 0.000
Z45.3 Adjustment and management of implanted hearing device
0.656 0.344 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.655 0.345 0.000
E40-E46 Malnutrition
0.655 0.345 0.000
M17 Gonarthrosis [arthrosis of knee]
0.655 0.345 0.000
N21 Calculus of lower urinary tract
0.655 0.345 0.000
Z96.6 Presence of orthopaedic joint implants
0.654 0.346 0.000
Z97.8 Presence of other specified devices
0.652 0.348 0.000
D80-D89 Certain disorders involving the immune mechanism
0.652 0.348 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.652 0.348 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.651 0.349 0.000
I88 Nonspecific lymphadenitis
0.651 0.349 0.000
I87 Other disorders of veins
0.651 0.349 0.000
I82 Other venous embolism and thrombosis
0.651 0.349 0.000
S59 Other and unspecified injuries of forearm
0.651 0.349 0.000
S58 Traumatic amputation of forearm
0.651 0.349 0.000
S57 Crushing injury of forearm
0.651 0.349 0.000
S56 Injury of muscle and tendon at forearm level
0.651 0.349 0.000
S55 Injury of blood vessels at forearm level
0.651 0.349 0.000
S54 Injury of nerves at forearm level
0.651 0.349 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.651 0.349 0.000
S51 Open wound of forearm
0.651 0.349 0.000
S50 Superficial injury of forearm
0.651 0.349 0.000
H33.3 Retinal breaks without detachment
0.650 0.349 0.000
N20.1 Calculus of ureter
0.649 0.351 0.000
H34 Retinal vascular occlusions
0.647 0.353 0.000
F99-F99 Unspecified mental disorder
0.646 0.353 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.646 0.353 0.000
F70-F79 Mental retardation
0.646 0.353 0.000
F60-F69 Disorders of adult personality and behaviour
0.646 0.353 0.000
K63.1 Perforation of intestine (nontraumatic)
0.647 0.353 0.000
K60.3 Anal fistula
0.645 0.355 0.000
K50.8 Other Crohn's disease
0.645 0.355 0.000
H60-H62 Diseases of external ear
0.645 0.355 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.643 0.357 0.000
T87.6 Other and unspecified complications of amputation stump
0.642 0.358 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.642 0.358 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.642 0.358 0.000
H31 Other disorders of choroid
0.642 0.358 0.000
H30 Chorioretinal inflammation
0.642 0.358 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.640 0.359 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.640 0.360 0.000
K51.4 Pseudopolyposis of colon
0.640 0.360 0.000
M47 Spondylosis
0.640 0.360 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.640 0.360 0.000
K03 Other diseases of hard tissues of teeth
0.640 0.360 0.000
K00 Disorders of tooth development and eruption
0.640 0.360 0.000
K07 Dentofacial anomalies [including malocclusion]
0.640 0.360 0.000
E10 Insulin-dependent diabetes mellitus
0.639 0.361 0.000
M81 Osteoporosis without pathological fracture
0.639 0.361 0.000
K61.4 Intrasphincteric abscess
0.638 0.362 0.000
K61.2 Anorectal abscess
0.638 0.362 0.000
K61.1 Rectal abscess
0.638 0.362 0.000
I62 Other nontraumatic intracranial haemorrhage
0.638 0.362 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.637 0.363 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.637 0.363 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.636 0.364 0.000
K60.5 Anorectal fistula
0.636 0.364 0.000
K60.4 Rectal fistula
0.636 0.364 0.000
K60.0 Acute anal fissure
0.636 0.364 0.000
T88.4 Failed or difficult intubation
0.636 0.364 0.000
N18.9 Chronic renal failure, unspecified
0.636 0.364 0.000
R81 Glycosuria
0.635 0.365 0.000
M06.8 Other specified rheumatoid arthritis
0.635 0.365 0.000
M06.4 Inflammatory polyarthropathy
0.635 0.365 0.000
M06.3 Rheumatoid nodule
0.635 0.365 0.000
M06.2 Rheumatoid bursitis
0.635 0.365 0.000
M06.1 Adult-onset Still's disease
0.635 0.365 0.000
K56.7 Ileus, unspecified
0.635 0.365 0.000
A80-A89 Viral infections of the central nervous system
0.634 0.366 0.000
R46 Symptoms and signs involving appearance and behaviour
0.634 0.366 0.000
R43 Disturbances of smell and taste
0.634 0.366 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.634 0.366 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.634 0.366 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.634 0.366 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.634 0.366 0.000
T83.2 Mechanical complication of graft of urinary organ
0.634 0.366 0.000
I69 Sequelae of cerebrovascular disease
0.633 0.367 0.000
N32 Other disorders of bladder
0.633 0.367 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.632 0.368 0.000
K37 Unspecified appendicitis
0.632 0.368 0.000
T93.2 Sequelae of other fractures of lower limb
0.631 0.369 0.000
K12 Stomatitis and related lesions
0.631 0.369 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.631 0.369 0.000
M50 Cervical disk disorders
0.631 0.369 0.000
R53 Malaise and fatigue
0.631 0.369 0.000
Z96.7 Presence of other bone and tendon implants
0.630 0.370 0.000
N41 Inflammatory diseases of prostate
0.630 0.370 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.630 0.370 0.000
Z85 Personal history of malignant neoplasm
0.629 0.371 0.000
N17.8 Other acute renal failure
0.629 0.371 0.000
N17.2 Acute renal failure with medullary necrosis
0.629 0.371 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.629 0.371 0.000
N17.0 Acute renal failure with tubular necrosis
0.629 0.371 0.000
R45 Symptoms and signs involving emotional state
0.629 0.371 0.000
D50.8 Other iron deficiency anaemias
0.629 0.371 0.000
F41 Other anxiety disorders
0.629 0.371 0.000
F43 Reaction to severe stress, and adjustment disorders
0.629 0.371 0.000
K77 Liver disorders in diseases classified elsewhere
0.629 0.371 0.000
K73 Chronic hepatitis, not elsewhere classified
0.629 0.371 0.000
K71 Toxic liver disease
0.629 0.371 0.000
R31 Unspecified haematuria
0.628 0.372 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.627 0.373 0.000
M34 Systemic sclerosis
0.627 0.373 0.000
M33 Dermatopolymyositis
0.627 0.373 0.000
M32 Systemic lupus erythematosus
0.627 0.373 0.000
M30 Polyarteritis nodosa and related conditions
0.627 0.373 0.000
M21 Other acquired deformities of limbs
0.627 0.373 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.627 0.373 0.000
I84.1 Internal haemorrhoids with other complications
0.626 0.374 0.000
K38 Other diseases of appendix
0.625 0.374 0.000
K36 Other appendicitis
0.625 0.374 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.625 0.375 0.000
D55-D59 Haemolytic anaemias
0.624 0.375 0.000
F45 Somatoform disorders
0.624 0.376 0.000
H52 Disorders of refraction and accommodation
0.624 0.376 0.000
N30.8 Other cystitis
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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