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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7740197
log Bayes Factor = 63.4771
Chromosome 6   position 26,663,478  (GRCh37) Explore rs7740197 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
E10.9 Without complications
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.998 0.002 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
E03 Other hypothyroidism
0.994 0.006 0.000
M17 Gonarthrosis [arthrosis of knee]
0.993 0.007 0.000
N40 Hyperplasia of prostate
0.000 0.007 0.993
E05.9 Thyrotoxicosis, unspecified
0.993 0.007 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
K90 Intestinal malabsorption
0.992 0.008 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.991 0.009 0.000
E03.9 Hypothyroidism, unspecified
0.990 0.010 0.000
H25-H28 Disorders of lens
0.988 0.012 0.000
E16 Other disorders of pancreatic internal secretion
0.984 0.016 0.000
M17.0 Primary gonarthrosis, bilateral
0.984 0.016 0.000
H30-H36 Disorders of choroid and retina
0.981 0.019 0.000
H26 Other cataract
0.978 0.022 0.000
E16.2 Hypoglycaemia, unspecified
0.977 0.023 0.000
M31 Other necrotising vasculopathies
0.976 0.024 0.000
E20-E35 Disorders of other endocrine glands
0.974 0.026 0.000
E27 Other disorders of adrenal gland
0.972 0.028 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.971 0.029 0.000
M34 Systemic sclerosis
0.967 0.033 0.000
E27.1 Primary adrenocortical insufficiency
0.963 0.037 0.000
L20-L30 Dermatitis and eczema
0.956 0.044 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.955 0.045 0.000
M31.6 Other giant cell arteritis
0.951 0.049 0.000
H26.9 Cataract, unspecified
0.946 0.054 0.000
K90.9 Intestinal malabsorption, unspecified
0.944 0.056 0.000
M65-M68 Disorders of synovium and tendon
0.943 0.057 0.000
H34 Retinal vascular occlusions
0.939 0.061 0.000
H53-H54 Visual disturbances and blindness
0.938 0.062 0.000
H26.4 After-cataract
0.937 0.063 0.000
E10.1 With ketoacidosis
0.937 0.063 0.000
M17.9 Gonarthrosis, unspecified
0.935 0.065 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.934 0.066 0.000
M67 Other disorders of synovium and tendon
0.930 0.070 0.000
M11 Other crystal arthropathies
0.927 0.073 0.000
M67.8 Other specified disorders of synovium and tendon
0.925 0.075 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.923 0.077 0.000
L40-L45 Papulosquamous disorders
0.923 0.077 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.922 0.078 0.000
K90-K93 Other diseases of the digestive system
0.920 0.079 0.000
L30 Other dermatitis
0.915 0.085 0.000
E10.3 With ophthalmic complications
0.914 0.086 0.000
Chapter XI Diseases of the digestive system
0.913 0.087 0.000
K75 Other inflammatory liver diseases
0.912 0.088 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.911 0.089 0.000
M34.1 CR(E)ST syndrome
0.911 0.089 0.000
M25 Other joint disorders, not elsewhere classified
0.911 0.089 0.000
K70-K77 Diseases of liver
0.910 0.090 0.000
H35 Other retinal disorders
0.909 0.091 0.000
L28 Lichen simplex chronicus and prurigo
0.906 0.094 0.000
Q50-Q56 Congenital malformations of genital organs
0.904 0.096 0.000
M19 Other arthrosis
0.901 0.099 0.000
M10 Gout
0.900 0.100 0.000
H35.3 Degeneration of macula and posterior pole
0.900 0.100 0.000
L40 Psoriasis
0.897 0.103 0.000
M07 Psoriatic and enteropathic arthropathies
0.895 0.105 0.000
M25.7 Osteophyte
0.894 0.106 0.000
H43-H45 Disorders of vitreous body and globe
0.888 0.112 0.000
E10.2 With renal complications
0.885 0.115 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.884 0.116 0.000
K75.4 Autoimmune hepatitis
0.884 0.116 0.000
L50-L54 Urticaria and erythema
0.883 0.117 0.000
K75.9 Inflammatory liver disease, unspecified
0.881 0.119 0.000
L30.9 Dermatitis, unspecified
0.880 0.120 0.000
E50-E64 Other nutritional deficiencies
0.878 0.122 0.000
M19.0 Primary arthrosis of other joints
0.876 0.124 0.000
H18 Other disorders of cornea
0.875 0.125 0.000
M11.2 Other chondrocalcinosis
0.868 0.132 0.000
H34.8 Other retinal vascular occlusions
0.865 0.135 0.000
L10-L14 Bullous disorders
0.864 0.136 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.860 0.140 0.000
M25.71 Osteophyte (Shoulder region)
0.860 0.140 0.000
H54 Blindness and low vision
0.857 0.143 0.000
M00-M03 Infectious arthropathies
0.853 0.147 0.000
M24 Other specific joint derangements
0.852 0.148 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.851 0.149 0.000
H46 Optic neuritis
0.849 0.151 0.000
L28.0 Lichen simplex chronicus
0.841 0.159 0.000
K75.8 Other specified inflammatory liver diseases
0.841 0.159 0.000
M34.9 Systemic sclerosis, unspecified
0.837 0.163 0.000
M08 Juvenile arthritis
0.834 0.166 0.000
E13 Other specified diabetes mellitus
0.833 0.167 0.000
M24.1 Other articular cartilage disorders
0.831 0.169 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.831 0.169 0.000
H18.5 Hereditary corneal dystrophies
0.826 0.174 0.000
H26.1 Traumatic cataract
0.826 0.174 0.000
M07.3 Other psoriatic arthropathies
0.824 0.176 0.000
E10.5 With peripheral circulatory complications
0.822 0.178 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.821 0.179 0.000
H31 Other disorders of choroid
0.820 0.180 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.819 0.181 0.000
M14 Arthropathies in other diseases classified elsewhere
0.815 0.185 0.000
L40.0 Psoriasis vulgaris
0.815 0.185 0.000
Q51 Congenital malformations of uterus and cervix
0.814 0.186 0.000
O46.9 Antepartum haemorrhage, unspecified
0.814 0.186 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.813 0.187 0.000
H18.6 Keratoconus
0.809 0.191 0.000
M25.9 Joint disorder, unspecified
0.807 0.193 0.000
E27.2 Addisonian crisis
0.806 0.194 0.000
M13 Other arthritis
0.800 0.200 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.800 0.200 0.000
L27 Dermatitis due to substances taken internally
0.799 0.201 0.000
K72 Hepatic failure, not elsewhere classified
0.799 0.201 0.000
H27 Other disorders of lens
0.798 0.202 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.798 0.202 0.000
H43 Disorders of vitreous body
0.797 0.203 0.000
L52 Erythema nodosum
0.793 0.207 0.000
Q53 Undescended testicle
0.793 0.207 0.000
H53 Visual disturbances
0.793 0.207 0.000
M35 Other systemic involvement of connective tissue
0.789 0.210 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.786 0.214 0.000
M17.5 Other secondary gonarthrosis
0.785 0.215 0.000
L40.1 Generalised pustular psoriasis
0.784 0.216 0.000
H53.1 Subjective visual disturbances
0.784 0.216 0.000
L40.3 Pustulosis palmaris et plantaris
0.782 0.218 0.000
M30 Polyarteritis nodosa and related conditions
0.780 0.220 0.000
M25.74 Osteophyte (Hand)
0.780 0.220 0.000
E10.8 With unspecified complications
0.779 0.221 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.779 0.221 0.000
M86-M90 Other osteopathies
0.778 0.222 0.000
M22 Disorders of patella
0.777 0.223 0.000
M31.7 Microscopic polyangiitis
0.777 0.223 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.775 0.225 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.774 0.226 0.000
M10.0 Idiopathic gout
0.771 0.229 0.000
M10.9 Gout, unspecified
0.769 0.231 0.000
E31 Polyglandular dysfunction
0.767 0.233 0.000
E10.7 With multiple complications
0.767 0.233 0.000
L50 Urticaria
0.767 0.233 0.000
L28.1 Prurigo nodularis
0.765 0.235 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.764 0.236 0.000
H10-H13 Disorders of conjunctiva
0.764 0.236 0.000
M17.3 Other posttraumatic gonarthrosis
0.763 0.237 0.000
L23 Allergic contact dermatitis
0.760 0.240 0.000
M67.4 Ganglion
0.760 0.240 0.000
M00 Pyogenic arthritis
0.759 0.241 0.000
K73 Chronic hepatitis, not elsewhere classified
0.757 0.243 0.000
H43.1 Vitreous haemorrhage
0.756 0.244 0.000
E55 Vitamin D deficiency
0.754 0.246 0.000
H34.9 Retinal vascular occlusion, unspecified
0.754 0.246 0.000
M13.0 Polyarthritis, unspecified
0.753 0.247 0.000
M34.8 Other forms of systemic sclerosis
0.753 0.247 0.000
O44 Placenta praevia
0.749 0.251 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.749 0.251 0.000
K71 Toxic liver disease
0.745 0.255 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.744 0.256 0.000
M35.0 Sicca syndrome [Sjogren]
0.742 0.258 0.000
M60-M63 Disorders of muscles
0.741 0.259 0.000
E40-E46 Malnutrition
0.741 0.259 0.000
H34.2 Other retinal artery occlusions
0.741 0.259 0.000
M32 Systemic lupus erythematosus
0.740 0.260 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.740 0.260 0.000
O48 Prolonged pregnancy
0.739 0.261 0.000
E61 Deficiency of other nutrient elements
0.739 0.261 0.000
M12 Other specific arthropathies
0.738 0.262 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.734 0.266 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.734 0.266 0.000
M18 Arthrosis of first carpometacarpal joint
0.734 0.266 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.733 0.267 0.000
H54.0 Blindness, both eyes
0.733 0.267 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.731 0.268 0.000
H34.1 Central retinal artery occlusion
0.729 0.271 0.000
L40.8 Other psoriasis
0.728 0.272 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.728 0.272 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.727 0.273 0.000
M86 Osteomyelitis
0.726 0.274 0.000
M19.2 Other secondary arthrosis
0.726 0.274 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.725 0.275 0.000
L11 Other acantholytic disorders
0.724 0.276 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.722 0.278 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.722 0.278 0.000
H30 Chorioretinal inflammation
0.722 0.278 0.000
M08.9 Juvenile arthritis, unspecified
0.720 0.279 0.000
L43 Lichen planus
0.720 0.280 0.000
L30.8 Other specified dermatitis
0.720 0.280 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.719 0.281 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.719 0.281 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.718 0.282 0.000
E10.6 With other specified complications
0.718 0.282 0.000
E24 Cushing's syndrome
0.718 0.282 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.715 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.715 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.715 0.284 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.715 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
E14 Unspecified diabetes mellitus
0.714 0.286 0.000
E13.9 Without complications
0.713 0.287 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.713 0.287 0.000
E03.5 Myxoedema coma
0.712 0.287 0.000
E03.4 Atrophy of thyroid (acquired)
0.712 0.287 0.000
E03.3 Postinfectious hypothyroidism
0.712 0.287 0.000
E03.1 Congenital hypothyroidism without goitre
0.712 0.287 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.712 0.287 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.712 0.288 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.712 0.288 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
K90.3 Pancreatic steatorrhoea
0.711 0.289 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.711 0.289 0.000
K90.1 Tropical sprue
0.711 0.289 0.000
E15 Nondiabetic hypoglycaemic coma
0.710 0.290 0.000
H35.8 Other specified retinal disorders
0.709 0.291 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.709 0.291 0.000
Q55 Other congenital malformations of male genital organs
0.708 0.292 0.000
H54.6 Unqualified visual loss, one eye
0.708 0.292 0.000
E10.0 With coma
0.707 0.293 0.000
H31.8 Other specified disorders of choroid
0.706 0.293 0.000
Q51.2 Other doubling of uterus
0.706 0.294 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.706 0.294 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.706 0.294 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.706 0.294 0.000
E16.4 Abnormal secretion of gastrin
0.706 0.294 0.000
E16.3 Increased secretion of glucagon
0.706 0.294 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.706 0.294 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.704 0.296 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.703 0.297 0.000
L50.0 Allergic urticaria
0.703 0.297 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.703 0.297 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.702 0.298 0.000
H35.2 Other proliferative retinopathy
0.702 0.298 0.000
O00-O08 Pregnancy with abortive outcome
0.701 0.299 0.000
H26.3 Drug-induced cataract
0.701 0.299 0.000
Q40 Other congenital malformations of upper alimentary tract
0.700 0.300 0.000
H54.7 Unspecified visual loss
0.700 0.300 0.000
M31.8 Other specified necrotising vasculopathies
0.700 0.300 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.700 0.300 0.000
M31.2 Lethal midline granuloma
0.700 0.300 0.000
M31.1 Thrombotic microangiopathy
0.700 0.300 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.700 0.300 0.000
H17 Corneal scars and opacities
0.700 0.300 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.699 0.301 0.000
E25 Adrenogenital disorders
0.699 0.301 0.000
K72.0 Acute and subacute hepatic failure
0.698 0.302 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.698 0.302 0.000
E32 Diseases of thymus
0.698 0.302 0.000
E30 Disorders of puberty, not elsewhere classified
0.698 0.302 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.698 0.302 0.000
H35.7 Separation of retinal layers
0.698 0.302 0.000
D55-D59 Haemolytic anaemias
0.697 0.303 0.000
E27.5 Adrenomedullary hyperfunction
0.697 0.303 0.000
E27.0 Other adrenocortical overactivity
0.697 0.303 0.000
Q27 Other congenital malformations of peripheral vascular system
0.697 0.303 0.000
H35.4 Peripheral retinal degeneration
0.696 0.304 0.000
M11.9 Crystal arthropathy, unspecified
0.695 0.305 0.000
L25 Unspecified contact dermatitis
0.695 0.305 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.694 0.306 0.000
M34.0 Progressive systemic sclerosis
0.694 0.306 0.000
E23 Hypofunction and other disorders of pituitary gland
0.694 0.306 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.693 0.307 0.000
M11.8 Other specified crystal arthropathies
0.693 0.307 0.000
M00.9 Pyogenic arthritis, unspecified
0.693 0.307 0.000
O46.8 Other antepartum haemorrhage
0.692 0.308 0.000
Q53.1 Undescended testicle, unilateral
0.691 0.309 0.000
M19.8 Other specified arthrosis
0.690 0.310 0.000
M67.0 Short Achilles tendon (acquired)
0.690 0.310 0.000
L12 Pemphigoid
0.689 0.311 0.000
M31.3 Wegener's granulomatosis
0.689 0.311 0.000
E20 Hypoparathyroidism
0.689 0.311 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.688 0.312 0.000
M14.6 Neuropathic arthropathy
0.688 0.312 0.000
M31.9 Necrotising vasculopathy, unspecified
0.688 0.312 0.000
H18.3 Changes in corneal membranes
0.686 0.314 0.000
L24 Irritant contact dermatitis
0.685 0.315 0.000
L26 Exfoliative dermatitis
0.685 0.315 0.000
L22 Diaper [napkin] dermatitis
0.685 0.315 0.000
H15 Disorders of sclera
0.684 0.316 0.000
E16.1 Other hypoglycaemia
0.680 0.319 0.000
Q28 Other congenital malformations of circulatory system
0.680 0.320 0.000
H18.0 Corneal pigmentations and deposits
0.677 0.323 0.000
C81 Hodgkin's disease
0.676 0.324 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.676 0.324 0.000
Q39 Congenital malformations of oesophagus
0.675 0.325 0.000
E51 Thiamine deficiency
0.675 0.325 0.000
L13 Other bullous disorders
0.675 0.325 0.000
M35.7 Hypermobility syndrome
0.675 0.325 0.000
H54.2 Low vision, both eyes
0.674 0.326 0.000
E03.8 Other specified hypothyroidism
0.673 0.327 0.000
H34.0 Transient retinal artery occlusion
0.673 0.327 0.000
O44.1 Placenta praevia with haemorrhage
0.671 0.329 0.000
M10.90 Gout, unspecified (Multiple sites)
0.670 0.330 0.000
M25.77 Osteophyte (Ankle and foot)
0.670 0.330 0.000
Q35-Q37 Cleft lip and cleft palate
0.670 0.330 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.670 0.330 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.670 0.330 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.670 0.330 0.000
H26.2 Complicated cataract
0.669 0.331 0.000
M66 Spontaneous rupture of synovium and tendon
0.669 0.331 0.000
H47.2 Optic atrophy
0.668 0.332 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.668 0.332 0.000
H44 Disorders of globe
0.667 0.333 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.667 0.333 0.000
M67.3 Transient synovitis
0.667 0.333 0.000
E55.9 Vitamin D deficiency, unspecified
0.665 0.335 0.000
M11.1 Familial chondrocalcinosis
0.665 0.335 0.000
M11.0 Hydroxyapatite deposition disease
0.665 0.335 0.000
M13.8 Other specified arthritis
0.665 0.335 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.665 0.335 0.000
M07.38 Other psoriatic arthropathies (Other)
0.664 0.336 0.000
D59 Acquired haemolytic anaemia
0.663 0.337 0.000
O00 Ectopic pregnancy
0.662 0.337 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.662 0.338 0.000
H27.1 Dislocation of lens
0.662 0.338 0.000
L44 Other papulosquamous disorders
0.662 0.338 0.000
L41 Parapsoriasis
0.662 0.338 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.662 0.338 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.661 0.339 0.000
Q51.3 Bicornate uterus
0.661 0.339 0.000
H31.9 Disorder of choroid, unspecified
0.661 0.339 0.000
Q52 Other congenital malformations of female genitalia
0.660 0.340 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.660 0.340 0.000
M17.1 Other primary gonarthrosis
0.660 0.340 0.000
H25 Senile cataract
0.660 0.340 0.000
D80-D89 Certain disorders involving the immune mechanism
0.659 0.341 0.000
M86.9 Osteomyelitis, unspecified
0.659 0.341 0.000
O43 Placental disorders
0.657 0.343 0.000
L30.5 Pityriasis alba
0.656 0.344 0.000
L30.2 Cutaneous autosensitisation
0.656 0.344 0.000
L30.1 Dyshidrosis [pompholyx]
0.656 0.344 0.000
L30.0 Nummular dermatitis
0.656 0.344 0.000
M31.0 Hypersensitivity angiitis
0.656 0.344 0.000
K75.2 Nonspecific reactive hepatitis
0.654 0.346 0.000
K75.1 Phlebitis of portal vein
0.654 0.346 0.000
M25.2 Flail joint
0.653 0.347 0.000
M25.1 Fistula of joint
0.653 0.347 0.000
K77 Liver disorders in diseases classified elsewhere
0.653 0.347 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.652 0.348 0.000
H35.1 Retinopathy of prematurity
0.652 0.348 0.000
O16 Unspecified maternal hypertension
0.652 0.348 0.000
L20 Atopic dermatitis
0.651 0.349 0.000
E22 Hyperfunction of pituitary gland
0.651 0.349 0.000
M33 Dermatopolymyositis
0.651 0.349 0.000
E61.1 Iron deficiency
0.651 0.349 0.000
H36 Retinal disorders in diseases classified elsewhere
0.650 0.350 0.000
H25.0 Senile incipient cataract
0.650 0.350 0.000
L28.2 Other prurigo
0.649 0.350 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.649 0.351 0.000
M10.94 Gout, unspecified (Hand)
0.648 0.352 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.648 0.352 0.000
L30.3 Infective dermatitis
0.648 0.352 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.648 0.352 0.000
E56 Other vitamin deficiencies
0.646 0.354 0.000
M10.4 Other secondary gout
0.645 0.354 0.000
M10.3 Gout due to impairment of renal function
0.645 0.354 0.000
M10.2 Drug-induced gout
0.645 0.354 0.000
M10.1 Lead-induced gout
0.645 0.354 0.000
O85-O92 Complications predominantly related to the puerperium
0.644 0.355 0.000
M22.8 Other disorders of patella
0.644 0.356 0.000
L40.9 Psoriasis, unspecified
0.644 0.356 0.000
M25.73 Osteophyte (Forearm)
0.643 0.356 0.000
L40.4 Guttate psoriasis
0.643 0.357 0.000
L40.2 Acrodermatitis continua
0.643 0.357 0.000
L30.4 Erythema intertrigo
0.643 0.357 0.000
M22.3 Other derangements of patella
0.643 0.357 0.000
C85.1 B-cell lymphoma, unspecified
0.642 0.358 0.000
M25.79 Osteophyte (Site unspecified)
0.642 0.358 0.000
M07.6 Other enteropathic arthropathies
0.641 0.358 0.000
M07.5 Arthropathy in ulcerative colitis
0.641 0.358 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.641 0.358 0.000
M07.2 Psoriatic spondylitis
0.641 0.358 0.000
M07.1 Arthritis mutilans
0.641 0.358 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.641 0.358 0.000
M25.70 Osteophyte (Multiple sites)
0.641 0.359 0.000
O36 Maternal care for other known or suspected foetal problems
0.640 0.360 0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)
0.639 0.361 0.000
K75.0 Abscess of liver
0.639 0.361 0.000
C81.9 Hodgkin's disease, unspecified
0.637 0.363 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.636 0.363 0.000
H54.9 Unspecified visual impairment (binocular)
0.635 0.365 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.634 0.366 0.000
H18.9 Disorder of cornea, unspecified
0.634 0.366 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.634 0.366 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.634 0.366 0.000
K90.8 Other intestinal malabsorption
0.633 0.367 0.000
L54 Erythema in diseases classified elsewhere
0.633 0.367 0.000
O00.1 Tubal pregnancy
0.632 0.368 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.631 0.368 0.000
C95 Leukaemia of unspecified cell type
0.632 0.368 0.000
C91 Lymphoid leukaemia
0.631 0.369 0.000
O31 Complications specific to multiple gestation
0.630 0.370 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.630 0.370 0.000
M30.0 Polyarteritis nodosa
0.630 0.370 0.000
Q27.3 Peripheral arteriovenous malformation
0.630 0.370 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.629 0.371 0.000
E63 Other nutritional deficiencies
0.629 0.371 0.000
E50 Vitamin A deficiency
0.629 0.371 0.000
E60 Dietary zinc deficiency
0.629 0.371 0.000
E59 Dietary selenium deficiency
0.629 0.371 0.000
E58 Dietary calcium deficiency
0.629 0.371 0.000
E54 Ascorbic acid deficiency
0.629 0.371 0.000
E52 Niacin deficiency [pellagra]
0.629 0.371 0.000
H11 Other disorders of conjunctiva
0.628 0.372 0.000
M19.08 Primary arthrosis of other joints (Other)
0.628 0.372 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.628 0.372 0.000
H18.7 Other corneal deformities
0.627 0.373 0.000
L50.9 Urticaria, unspecified
0.627 0.373 0.000
Q50.5 Embryonic cyst of broad ligament
0.626 0.374 0.000
H53.8 Other visual disturbances
0.626 0.374 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.624 0.376 0.000
H43.2 Crystalline deposits in vitreous body
0.623 0.377 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.623 0.377 0.000
M11.29 Other chondrocalcinosis (Site unspecified)
0.622 0.378 0.000
M11.28 Other chondrocalcinosis (Other)
0.622 0.378 0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)
0.622 0.378 0.000
M11.24 Other chondrocalcinosis (Hand)
0.622 0.378 0.000
M11.23 Other chondrocalcinosis (Forearm)
0.622 0.378 0.000
M11.22 Other chondrocalcinosis (Upper arm)
0.622 0.378 0.000
M11.21 Other chondrocalcinosis (Shoulder region)
0.622 0.378 0.000
M11.20 Other chondrocalcinosis (Multiple sites)
0.622 0.378 0.000
O33 Maternal care for known or suspected disproportion
0.621 0.379 0.000
H18.8 Other specified disorders of cornea
0.620 0.380 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.620 0.380 0.000
M25.3 Other instability of joint
0.620 0.380 0.000
E31.0 Autoimmune polyglandular failure
0.619 0.380 0.000
L10 Pemphigus
0.619 0.381 0.000
L14 Bullous disorders in diseases classified elsewhere
0.619 0.381 0.000
K72.9 Hepatic failure, unspecified
0.619 0.381 0.000
E14.1 With ketoacidosis
0.619 0.381 0.000
Q53.9 Undescended testicle, unspecified
0.619 0.381 0.000
M40-M43 Deforming dorsopathies
0.619 0.381 0.000
H16 Keratitis
0.617 0.383 0.000
H54.3 Unqualified visual loss, both eyes
0.614 0.385 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.613 0.387 0.000
Q45 Other congenital malformations of digestive system
0.613 0.387 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.611 0.389 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.611 0.389 0.000
M24.9 Joint derangement, unspecified
0.611 0.389 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.611 0.389 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.610 0.389 0.000
E05.8 Other thyrotoxicosis
0.610 0.390 0.000
Q60-Q64 Congenital malformations of the urinary system
0.610 0.390 0.000
H11.3 Conjunctival haemorrhage
0.610 0.390 0.000
E24.2 Drug-induced Cushing's syndrome
0.609 0.391 0.000
H27.0 Aphakia
0.609 0.391 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.608 0.391 0.000
M25.76 Osteophyte (Lower leg)
0.608 0.392 0.000
Q40.2 Other specified congenital malformations of stomach
0.607 0.393 0.000
H35.5 Hereditary retinal dystrophy
0.606 0.393 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.606 0.394 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.605 0.395 0.000
M67.43 Ganglion, wrist
0.605 0.395 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.604 0.396 0.000
O24 Diabetes mellitus in pregnancy
0.602 0.398 0.000
L11.0 Acquired keratosis follicularis
0.602 0.398 0.000
D86 Sarcoidosis
0.601 0.399 0.000
M19.23 Other secondary arthrosis (Forearm)
0.601 0.399 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.601 0.399 0.000
E27.9 Disorder of adrenal gland, unspecified
0.600 0.400 0.000
H31.3 Choroidal haemorrhage and rupture
0.600 0.400 0.000
O04 Medical abortion
0.600 0.400 0.000
M86.6 Other chronic osteomyelitis
0.599 0.400 0.000
L23.1 Allergic contact dermatitis due to adhesives
0.598 0.402 0.000
M08.8 Other juvenile arthritis
0.598 0.402 0.000
M08.4 Pauciarticular juvenile arthritis
0.598 0.402 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.598 0.402 0.000
M08.2 Juvenile arthritis with systemic onset
0.598 0.402 0.000
M08.1 Juvenile ankylosing spondylitis
0.598 0.402 0.000
M08.0 Juvenile rheumatoid arthritis
0.598 0.402 0.000
C91.1 Chronic lymphocytic leukaemia
0.598 0.402 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.598 0.402 0.000
E13.8 With unspecified complications
0.597 0.403 0.000
E13.7 With multiple complications
0.597 0.403 0.000
E13.6 With other specified complications
0.597 0.403 0.000
E13.5 With peripheral circulatory complications
0.597 0.403 0.000
E13.4 With neurological complications
0.597 0.403 0.000
E13.3 With ophthalmic complications
0.597 0.403 0.000
E13.2 With renal complications
0.597 0.403 0.000
E13.1 With ketoacidosis
0.597 0.403 0.000
E13.0 With coma
0.597 0.403 0.000
H54.5 Low vision, one eye
0.597 0.403 0.000
H43.9 Disorder of vitreous body, unspecified
0.597 0.403 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.596 0.404 0.000
M24.18 Other articular cartilage disorders (Other)
0.596 0.404 0.000
M24.14 Other articular cartilage disorders (Hand)
0.596 0.404 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.596 0.404 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.596 0.404 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.596 0.404 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.596 0.404 0.000
Q43 Other congenital malformations of intestine
0.596 0.404 0.000
H18.1 Bullous keratopathy
0.592 0.408 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.591 0.409 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.591 0.409 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.591 0.409 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.591 0.409 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.591 0.409 0.000
M24.7 Protrusio acetabuli
0.590 0.410 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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