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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7746199
log Bayes Factor = 87.2247
Chromosome 6   position 27,261,324  (GRCh37) Explore rs7746199 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
E27 Other disorders of adrenal gland
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
E27.1 Primary adrenocortical insufficiency
0.994 0.006 0.000
E16.2 Hypoglycaemia, unspecified
0.994 0.006 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.006 0.994
T42.4 Benzodiazepines
0.000 0.008 0.992
E03 Other hypothyroidism
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.009 0.991
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.012 0.988
T39.1 4-Aminophenol derivatives
0.000 0.013 0.987
E03.9 Hypothyroidism, unspecified
0.983 0.017 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.021 0.979
N40 Hyperplasia of prostate
0.000 0.023 0.977
E10.3 With ophthalmic complications
0.976 0.024 0.000
R31 Unspecified haematuria
0.000 0.024 0.976
E27.4 Other and unspecified adrenocortical insufficiency
0.964 0.036 0.000
E14 Unspecified diabetes mellitus
0.927 0.073 0.000
E10.1 With ketoacidosis
0.911 0.089 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.908 0.092 0.000
E10.2 With renal complications
0.899 0.101 0.000
E24 Cushing's syndrome
0.897 0.103 0.000
T39.0 Salicylates
0.000 0.115 0.885
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.122 0.878
E50-E64 Other nutritional deficiencies
0.858 0.142 0.000
E10.5 With peripheral circulatory complications
0.845 0.155 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.156 0.844
E31 Polyglandular dysfunction
0.836 0.164 0.000
E13 Other specified diabetes mellitus
0.825 0.175 0.000
E24.2 Drug-induced Cushing's syndrome
0.824 0.175 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.815 0.185 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.189 0.811
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.194 0.806
E14.1 With ketoacidosis
0.804 0.196 0.000
E14.3 With ophthalmic complications
0.802 0.198 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.203 0.797
E27.3 Drug-induced adrenocortical insufficiency
0.792 0.208 0.000
E16.1 Other hypoglycaemia
0.790 0.210 0.000
E40-E46 Malnutrition
0.778 0.222 0.000
E20 Hypoparathyroidism
0.775 0.225 0.000
K90 Intestinal malabsorption
0.771 0.229 0.000
E24.0 Pituitary-dependent Cushing's disease
0.761 0.239 0.000
E22 Hyperfunction of pituitary gland
0.747 0.253 0.000
E53 Deficiency of other B group vitamins
0.746 0.254 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.255 0.745
E27.2 Addisonian crisis
0.744 0.256 0.000
T36 Poisoning by systemic antibiotics
0.000 0.261 0.739
T42.0 Hydantoin derivatives
0.000 0.262 0.738
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.262 0.738
E10.6 With other specified complications
0.737 0.262 0.000
E25 Adrenogenital disorders
0.732 0.268 0.000
E10.0 With coma
0.730 0.270 0.000
E05.8 Other thyrotoxicosis
0.726 0.273 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.275 0.725
E14.2 Withrenal complications
0.723 0.277 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.722 0.278 0.000
E31.0 Autoimmune polyglandular failure
0.720 0.280 0.000
E34 Other endocrine disorders
0.720 0.280 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.715 0.285 0.000
E27.0 Other adrenocortical overactivity
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.287 0.712
T42.3 Barbiturates
0.000 0.287 0.712
T42.2 Succinimides and oxazolidinediones
0.000 0.287 0.712
E03.5 Myxoedema coma
0.711 0.289 0.000
E03.4 Atrophy of thyroid (acquired)
0.711 0.289 0.000
E03.3 Postinfectious hypothyroidism
0.711 0.289 0.000
E03.1 Congenital hypothyroidism without goitre
0.711 0.289 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.290 0.710
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.290 0.710
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.290 0.710
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.290 0.710
T39.4 Antirheumatics, not elsewhere classified
0.000 0.291 0.709
T39.2 Pyrazolone derivatives
0.000 0.291 0.709
E13.9 Without complications
0.699 0.301 0.000
T42.1 Iminostilbenes
0.000 0.302 0.698
T40.4 Other synthetic narcotics
0.000 0.303 0.697
E10.8 With unspecified complications
0.696 0.304 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.305 0.695
E03.8 Other specified hypothyroidism
0.693 0.307 0.000
E14.6 With other specified complications
0.691 0.309 0.000
E10.4 With neurological complications
0.688 0.312 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.312 0.688
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.317 0.682
K90.9 Intestinal malabsorption, unspecified
0.681 0.319 0.000
E14.5 With peripheral circulatory complications
0.679 0.321 0.000
E23 Hypofunction and other disorders of pituitary gland
0.673 0.327 0.000
T40.2 Other opioids
0.000 0.327 0.673
E11 Non-insulin-dependent diabetes mellitus
0.672 0.328 0.000
E26 Hyperaldosteronism
0.668 0.332 0.000
E14.9 Without complications
0.666 0.334 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.335 0.664
E14.7 With multiple complications
0.664 0.336 0.000
E14.0 With coma
0.664 0.336 0.000
E61 Deficiency of other nutrient elements
0.664 0.336 0.000
E07 Other disorders of thyroid
0.660 0.340 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.647 0.353 0.000
E53.8 Deficiency of other specified B group vitamins
0.645 0.355 0.000
E56 Other vitamin deficiencies
0.644 0.356 0.000
E24.8 Other Cushing's syndrome
0.643 0.357 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.643 0.357 0.000
E24.3 Ectopic ACTH syndrome
0.643 0.357 0.000
E24.1 Nelson's syndrome
0.643 0.357 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.635 0.365 0.000
E14.8 With unspecified complications
0.633 0.367 0.000
E29 Testicular dysfunction
0.631 0.369 0.000
T50.8 Diagnostic agents
0.000 0.371 0.629
T50.7 Analeptics and opioid receptor antagonists
0.000 0.371 0.629
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.371 0.629
T50.5 Appetite depressants
0.000 0.371 0.629
T50.4 Drugs affecting uric acid metabolism
0.000 0.371 0.629
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.371 0.629
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.371 0.629
T50.1 Loop [high-ceiling] diuretics
0.000 0.371 0.629
T50.0 Mineralocorticoids and their antagonists
0.000 0.371 0.629
T43.6 Psychostimulants with abuse potential
0.000 0.381 0.619
E46 Unspecified protein-energy malnutrition
0.618 0.382 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.615 0.384 0.000
E63 Other nutritional deficiencies
0.615 0.384 0.000
E50 Vitamin A deficiency
0.615 0.384 0.000
E60 Dietary zinc deficiency
0.615 0.384 0.000
E59 Dietary selenium deficiency
0.615 0.384 0.000
E58 Dietary calcium deficiency
0.615 0.384 0.000
E54 Ascorbic acid deficiency
0.615 0.384 0.000
E52 Niacin deficiency [pellagra]
0.615 0.384 0.000
E20.9 Hypoparathyroidism, unspecified
0.615 0.385 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.387 0.613
T40.6 Other and unspecified narcotics
0.000 0.394 0.606
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.395 0.605
T40.8 Lysergide [LSD]
0.000 0.395 0.605
T40.7 Cannabis (derivatives)
0.000 0.395 0.605
T40.5 Cocaine
0.000 0.395 0.605
T40.3 Methadone
0.000 0.395 0.605
T40.1 Heroin
0.000 0.395 0.605
T40.0 Opium
0.000 0.395 0.605
N40-N51 Diseases of male genital organs
0.000 0.396 0.604
E51 Thiamine deficiency
0.603 0.397 0.000
E14.4 With neurological complications
0.602 0.398 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.400 0.600
E31.9 Polyglandular dysfunction, unspecified
0.599 0.400 0.000
E31.8 Other polyglandular dysfunction
0.599 0.400 0.000
E31.1 Polyglandular hyperfunction
0.599 0.400 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.593 0.407 0.000
E13.8 With unspecified complications
0.591 0.409 0.000
E13.7 With multiple complications
0.591 0.409 0.000
E13.6 With other specified complications
0.591 0.409 0.000
E13.5 With peripheral circulatory complications
0.591 0.409 0.000
E13.4 With neurological complications
0.591 0.409 0.000
E13.3 With ophthalmic complications
0.591 0.409 0.000
E13.2 With renal complications
0.591 0.409 0.000
E13.1 With ketoacidosis
0.591 0.409 0.000
E13.0 With coma
0.591 0.409 0.000
N41 Inflammatory diseases of prostate
0.000 0.412 0.588
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.414 0.586
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.417 0.582
T43.9 Psychotropic drug, unspecified
0.000 0.418 0.581
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.418 0.581
E11.5 With peripheral circulatory complications
0.581 0.419 0.000
E53.9 Vitamin B deficiency, unspecified
0.578 0.422 0.000
E34.9 Endocrine disorder, unspecified
0.577 0.422 0.000
T45.0 Antiallergic and antiemetic drugs
0.000 0.431 0.569
N41.1 Chronic prostatitis
0.000 0.434 0.566
N42 Other disorders of prostate
0.000 0.434 0.566
E55 Vitamin D deficiency
0.564 0.436 0.000
E22.1 Hyperprolactinaemia
0.560 0.440 0.000
T36.0 Penicillins
0.000 0.442 0.558
N41.0 Acute prostatitis
0.000 0.442 0.558
E44 Protein-energy malnutrition of moderate and mild degree
0.558 0.442 0.000
E45 Retarded development following protein-energy malnutrition
0.558 0.442 0.000
E43 Unspecified severe protein-energy malnutrition
0.558 0.442 0.000
E42 Marasmic kwashiorkor
0.558 0.442 0.000
E41 Nutritional marasmus
0.558 0.442 0.000
E40 Kwashiorkor
0.558 0.442 0.000
E20.8 Other hypoparathyroidism
0.556 0.444 0.000
E20.1 Pseudohypoparathyroidism
0.556 0.444 0.000
E20.0 Idiopathic hypoparathyroidism
0.556 0.444 0.000
K90.8 Other intestinal malabsorption
0.553 0.447 0.000
K90.3 Pancreatic steatorrhoea
0.553 0.447 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.553 0.447 0.000
K90.1 Tropical sprue
0.553 0.447 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.542 0.458 0.000
N42.8 Other specified disorders of prostate
0.000 0.464 0.536
E22.9 Hyperfunction of pituitary gland, unspecified
0.536 0.464 0.000
E22.8 Other hyperfunction of pituitary gland
0.536 0.464 0.000
E53.1 Pyridoxine deficiency
0.535 0.465 0.000
E53.0 Riboflavin deficiency
0.535 0.465 0.000
E11.6 With other specified complications
0.533 0.467 0.000
T43.2 Other and unspecified antidepressants
0.000 0.468 0.532
E04 Other non-toxic goitre
0.531 0.468 0.001
T36.9 Systemic antibiotic, unspecified
0.000 0.470 0.530
T36.8 Other systemic antibiotics
0.000 0.470 0.530
T36.7 Antifungal antibiotics, systemically used
0.000 0.470 0.530
T36.6 Rifamycins
0.000 0.470 0.530
T36.5 Aminoglycosides
0.000 0.470 0.530
T36.4 Tetracyclines
0.000 0.470 0.530
T36.3 Macrolides
0.000 0.470 0.530
T36.2 Chloramphenicol group
0.000 0.470 0.530
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.470 0.530
E61.1 Iron deficiency
0.526 0.474 0.000
E25.9 Adrenogenital disorder, unspecified
0.525 0.475 0.000
E25.8 Other adrenogenital disorders
0.525 0.475 0.000
E11.0 With coma
0.524 0.476 0.000
T45.2 Vitamins, not elsewhere classified
0.000 0.477 0.523
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.480 0.520
T45.8 Other primarily systemic and haematological agents
0.000 0.480 0.520
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.480 0.520
T45.6 Fibrinolysis-affecting drugs
0.000 0.480 0.520
T45.4 Iron and its compounds
0.000 0.480 0.520
T45.3 Enzymes, not elsewhere classified
0.000 0.480 0.520
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.481 0.518
E06 Thyroiditis
0.518 0.482 0.000
T45.5 Anticoagulants
0.000 0.482 0.518
E27.9 Disorder of adrenal gland, unspecified
0.517 0.482 0.000
E11.2 With renal complications
0.517 0.483 0.000
E34.5 Androgen resistance syndrome
0.516 0.484 0.000
E34.4 Constitutional tall stature
0.516 0.484 0.000
E34.3 Short stature, not elsewhere classified
0.516 0.484 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.516 0.484 0.000
E34.1 Other hypersecretion of intestinal hormones
0.516 0.484 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.485 0.515
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E23.7 Disorder of pituitary gland, unspecified
0.513 0.487 0.000
E30.9 Disorder of puberty, unspecified
0.513 0.487 0.000
E30.8 Other disorders of puberty
0.513 0.487 0.000
E30.1 Precocious puberty
0.513 0.487 0.000
E30.0 Delayed puberty
0.513 0.487 0.000
E32.9 Disease of thymus, unspecified
0.513 0.487 0.000
E32.8 Other diseases of thymus
0.513 0.487 0.000
E32.1 Abscess of thymus
0.513 0.487 0.000
E32.0 Persistent hyperplasia of thymus
0.513 0.487 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.513 0.487 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.513 0.487 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.513 0.487 0.000
E34.8 Other specified endocrine disorders
0.513 0.487 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.491 0.509
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.491 0.509
T37.5 Antiviral drugs
0.000 0.491 0.509
T37.4 Anthelminthics
0.000 0.491 0.509
T37.3 Other antiprotozoal drugs
0.000 0.491 0.509
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.491 0.509
T37.1 Antimycobacterial drugs
0.000 0.491 0.509
T37.0 Sulphonamides
0.000 0.491 0.509
T41.5 Therapeutic gases
0.000 0.491 0.509
T41.4 Anaesthetic, unspecified
0.000 0.491 0.509
T41.3 Local anaesthetics
0.000 0.491 0.509
T41.2 Other and unspecified general anaesthetics
0.000 0.491 0.509
T41.1 Intravenous anaesthetics
0.000 0.491 0.509
T41.0 Inhaled anaesthetics
0.000 0.491 0.509
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.491 0.509
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.491 0.509
T48.5 Anti-common-cold drugs
0.000 0.491 0.509
T48.4 Expectorants
0.000 0.491 0.509
T48.3 Antitussives
0.000 0.491 0.509
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.491 0.509
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.491 0.509
T48.0 Oxytocic drugs
0.000 0.491 0.509
T49.9 Topical agent, unspecified
0.000 0.491 0.509
T49.8 Other topical agents
0.000 0.491 0.509
T49.7 Dental drugs, topically applied
0.000 0.491 0.509
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.491 0.509
T49.5 Ophthalmological drugs and preparations
0.000 0.491 0.509
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.491 0.509
T49.3 Emollients, demulcents and protectants
0.000 0.491 0.509
T49.2 Local astringents and local detergents
0.000 0.491 0.509
T49.1 Antipruritics
0.000 0.491 0.509
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.491 0.509
E04.9 Non-toxic goitre, unspecified
0.502 0.498 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.498 0.502
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.501 0.498
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.501 0.498
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.501 0.498
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.501 0.498
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.501 0.498
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.501 0.498
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.501 0.498
T44.0 Anticholinesterase agents
0.000 0.501 0.498
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.506 0.493
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.506 0.493
T47.7 Emetics
0.000 0.506 0.493
T47.6 Antidiarrhoeal drugs
0.000 0.506 0.493
T47.5 Digestants
0.000 0.506 0.493
T47.3 Saline and osmotic laxatives
0.000 0.506 0.493
T47.2 Stimulant laxatives
0.000 0.506 0.493
T47.0 Histamine H(2)-receptor antagonists
0.000 0.506 0.493
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.507 0.493
E56.1 Deficiency of vitamin K
0.489 0.510 0.000
E28 Ovarian dysfunction
0.483 0.517 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.483 0.517 0.000
E23.1 Drug-induced hypopituitarism
0.483 0.517 0.000
E11.7 With multiple complications
0.482 0.518 0.000
E23.2 Diabetes insipidus
0.480 0.520 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.520 0.480
E26.9 Hyperaldosteronism, unspecified
0.479 0.521 0.000
E26.8 Other hyperaldosteronism
0.479 0.521 0.000
E26.1 Secondary hyperaldosteronism
0.479 0.521 0.000
E23.6 Other disorders of pituitary gland
0.478 0.522 0.000
E61.9 Deficiency of nutrient element, unspecified
0.476 0.524 0.000
E61.8 Deficiency of other specified nutrient elements
0.476 0.524 0.000
E61.7 Deficiency of multiple nutrient elements
0.476 0.524 0.000
E61.6 Vanadium deficiency
0.476 0.524 0.000
E61.5 Molybdenum deficiency
0.476 0.524 0.000
E61.4 Chromium deficiency
0.476 0.524 0.000
E61.3 Manganese deficiency
0.476 0.524 0.000
E61.0 Copper deficiency
0.476 0.524 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.525 0.475
E61.2 Magnesium deficiency
0.474 0.526 0.000
E07.1 Dyshormogenetic goitre
0.473 0.527 0.000
E07.0 Hypersecretion of calcitonin
0.473 0.527 0.000
E07.8 Other specified disorders of thyroid
0.472 0.527 0.000
E11.1 With ketoacidosis
0.471 0.529 0.000
E11.4 With neurological complications
0.471 0.529 0.000
E22.0 Acromegaly and pituitary gigantism
0.468 0.532 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.467 0.532 0.000
E56.9 Vitamin deficiency, unspecified
0.461 0.538 0.000
E56.8 Deficiency of other vitamins
0.461 0.538 0.000
E56.0 Deficiency of vitamin E
0.461 0.538 0.000
N42.0 Calculus of prostate
0.000 0.544 0.455
N46 Male infertility
0.000 0.547 0.453
E29.9 Testicular dysfunction, unspecified
0.452 0.548 0.000
E29.8 Other testicular dysfunction
0.452 0.548 0.000
E29.0 Testicular hyperfunction
0.452 0.548 0.000
T47.4 Other laxatives
0.000 0.555 0.445
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.557 0.442
E50.9 Vitamin A deficiency, unspecified
0.441 0.558 0.000
E50.8 Other manifestations of vitamin A deficiency
0.441 0.558 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.441 0.558 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.441 0.558 0.000
E50.5 Vitamin A deficiency with night blindness
0.441 0.558 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.441 0.558 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.441 0.558 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.441 0.558 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.441 0.558 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.441 0.558 0.000
E63.9 Nutritional deficiency, unspecified
0.441 0.558 0.000
E63.8 Other specified nutritional deficiencies
0.441 0.558 0.000
E63.1 Imbalance of constituents of food intake
0.441 0.558 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.441 0.558 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.441 0.558 0.000
E64.8 Sequelae of other nutritional deficiencies
0.441 0.558 0.000
E64.3 Sequelae of rickets
0.441 0.558 0.000
E64.2 Sequelae of vitamin C deficiency
0.441 0.558 0.000
E64.1 Sequelae of vitamin A deficiency
0.441 0.558 0.000
E64.0 Sequelae of protein-energy malnutrition
0.441 0.558 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.559 0.440
N42.1 Congestion and haemorrhage of prostate
0.000 0.561 0.439
E34.0 Carcinoid syndrome
0.438 0.561 0.000
N42.2 Atrophy of prostate
0.000 0.562 0.438
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.567 0.433
E51.9 Thiamine deficiency, unspecified
0.432 0.567 0.000
E51.8 Other manifestations of thiamine deficiency
0.432 0.567 0.000
E51.1 Beriberi
0.432 0.567 0.000
E26.0 Primary hyperaldosteronism
0.432 0.568 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.569 0.430
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.569 0.430
T38.7 Androgens and anabolic congeners
0.000 0.569 0.430
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.569 0.430
T38.5 Other oestrogens and progestogens
0.000 0.569 0.430
T38.4 Oral contraceptives
0.000 0.569 0.430
T38.2 Antithyroid drugs
0.000 0.569 0.430
T38.0 Glucocorticoids and synthetic analogues
0.000 0.569 0.430
T46.1 Calcium-channel blockers
0.000 0.574 0.426
E24.9 Cushing's syndrome, unspecified
0.424 0.575 0.000
N48 Other disorders of penis
0.000 0.578 0.422
N41.3 Prostatocystitis
0.000 0.578 0.422
N41.2 Abscess of prostate
0.000 0.578 0.422
E51.2 Wernicke's encephalopathy
0.420 0.580 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.582 0.418
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.582 0.418
T46.7 Peripheral vasodilators
0.000 0.582 0.418
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.582 0.418
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.582 0.418
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.582 0.418
E07.9 Disorder of thyroid, unspecified
0.417 0.583 0.000
T38.1 Thyroid hormones and substitutes
0.000 0.587 0.413
E11.3 With ophthalmic complications
0.410 0.590 0.000
E23.0 Hypopituitarism
0.407 0.593 0.000
N42.3 Dysplasia of prostate
0.000 0.594 0.406
E55.0 Rickets, active
0.405 0.595 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.598 0.401
E44.1 Mild protein-energy malnutrition
0.400 0.600 0.000
E44.0 Moderate protein-energy malnutrition
0.400 0.600 0.000
E27.8 Other specified disorders of adrenal gland
0.396 0.603 0.001
E11.8 With unspecified complications
0.395 0.605 0.000
N44 Torsion of testis
0.000 0.605 0.395
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.612 0.387
N48.1 Balanoposthitis
0.000 0.614 0.386
E04.8 Other specified non-toxic goitre
0.381 0.619 0.001
N48.2 Other inflammatory disorders of penis
0.000 0.622 0.378
E06.5 Other chronic thyroiditis
0.371 0.628 0.000
E06.4 Drug-induced thyroiditis
0.371 0.628 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.371 0.628 0.000
E06.1 Subacute thyroiditis
0.371 0.628 0.000
E06.0 Acute thyroiditis
0.371 0.628 0.000
E29.1 Testicular hypofunction
0.367 0.633 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.641 0.358
E04.0 Non-toxic diffuse goitre
0.356 0.643 0.001
E55.9 Vitamin D deficiency, unspecified
0.353 0.647 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.647 0.353
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.647 0.353
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.647 0.353
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.653 0.347
E28.9 Ovarian dysfunction, unspecified
0.346 0.653 0.000
E28.8 Other ovarian dysfunction
0.346 0.653 0.000
E28.1 Androgen excess
0.346 0.653 0.000
E28.0 Oestrogen excess
0.346 0.653 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.654 0.345
E06.9 Thyroiditis, unspecified
0.342 0.657 0.000
N48.5 Ulcer of penis
0.000 0.673 0.327
N48.3 Priapism
0.000 0.678 0.322
E65-E68 Obesity and other hyperalimentation
0.314 0.686 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.689 0.310
N51.2 Balanitis in diseases classified elsewhere
0.000 0.689 0.310
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.689 0.310
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.689 0.310
N48.0 Leukoplakia of penis
0.000 0.691 0.309
N45 Orchitis and epididymitis
0.000 0.694 0.306
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.706 0.294
R30-R39 Symptoms and signs involving the urinary system
0.000 0.710 0.290
N48.9 Disorder of penis, unspecified
0.000 0.716 0.284
F32.9 Depressive episode, unspecified
0.000 0.719 0.281
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.720 0.280
E28.3 Primary ovarian failure
0.277 0.722 0.000
F32 Depressive episode
0.000 0.726 0.274
F30-F39 Mood [affective] disorders
0.000 0.730 0.269
F33 Recurrent depressive disorder
0.000 0.734 0.266
F33.9 Recurrent depressive disorder, unspecified
0.000 0.739 0.261
R35 Polyuria
0.000 0.744 0.256
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.747 0.253
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.749 0.251
E28.2 Polycystic ovarian syndrome
0.238 0.762 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.767 0.233
F39 Unspecified mood [affective] disorder
0.000 0.769 0.231
E06.3 Autoimmune thyroiditis
0.229 0.771 0.000
N43 Hydrocele and spermatocele
0.000 0.771 0.229
E67 Other hyperalimentation
0.225 0.774 0.000
E68 Sequelae of hyperalimentation
0.225 0.774 0.000
F30 Manic episode
0.000 0.775 0.225
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.779 0.221
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.780 0.220
N48.4 Impotence of organic origin
0.000 0.783 0.217
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.784 0.216
R34 Anuria and oliguria
0.000 0.787 0.213
F32.8 Other depressive episodes
0.000 0.789 0.211
R32 Unspecified urinary incontinence
0.000 0.800 0.200
R39 Other symptoms and signs involving the urinary system
0.000 0.801 0.199
F31 Bipolar affective disorder
0.000 0.803 0.197
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.195 0.805 0.001
F30.0 Hypomania
0.000 0.806 0.194
F38 Other mood [affective] disorders
0.000 0.807 0.193
E11.9 Without complications
0.193 0.807 0.000
F33.8 Other recurrent depressive disorders
0.000 0.809 0.190
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.809 0.190
F34 Persistent mood [affective] disorders
0.000 0.812 0.188
R33 Retention of urine
0.000 0.812 0.188
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.819 0.181
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.820 0.180
R36 Urethral discharge
0.000 0.824 0.176

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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