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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7749305
log Bayes Factor = 164.186
Chromosome 6   position 27,446,566  (GRCh37) Explore rs7749305 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
K40 Inguinal hernia
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
N39 Other disorders of urinary system
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
K40-K46 Hernia
0.000 0.001 0.999
N40-N51 Diseases of male genital organs
0.000 0.001 0.999
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.001 0.999
K44 Diaphragmatic hernia
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.998 0.002 0.000
H25-H28 Disorders of lens
0.997 0.003 0.000
H26.9 Cataract, unspecified
0.997 0.003 0.000
H26 Other cataract
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.994 0.006 0.000
Chapter XI Diseases of the digestive system
0.150 0.007 0.843
N39.8 Other specified disorders of urinary system
0.000 0.009 0.991
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.010 0.990
D80-D89 Certain disorders involving the immune mechanism
0.988 0.012 0.000
N42 Other disorders of prostate
0.000 0.013 0.987
K90-K93 Other diseases of the digestive system
0.152 0.015 0.833
H36 Retinal disorders in diseases classified elsewhere
0.984 0.016 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.017 0.983
M05-M14 Inflammatory polyarthropathies
0.982 0.018 0.000
N32 Other disorders of bladder
0.000 0.019 0.981
Chapter XII Diseases of the skin and subcutaneous tissue
0.979 0.021 0.000
N32.0 Bladder-neck obstruction
0.000 0.022 0.978
E05.0 Thyrotoxicosis with diffuse goitre
0.978 0.022 0.000
M15-M19 Arthrosis
0.976 0.024 0.000
H36.0 Diabetic retinopathy
0.975 0.025 0.000
M17 Gonarthrosis [arthrosis of knee]
0.974 0.026 0.000
M17.9 Gonarthrosis, unspecified
0.973 0.027 0.000
H43-H45 Disorders of vitreous body and globe
0.967 0.033 0.000
D86 Sarcoidosis
0.965 0.035 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.963 0.037 0.000
M20.1 Hallux valgus (acquired)
0.000 0.040 0.960
E14 Unspecified diabetes mellitus
0.958 0.042 0.000
M23 Internal derangement of knee
0.958 0.042 0.000
M20 Acquired deformities of fingers and toes
0.001 0.044 0.955
N80-N98 Noninflammatory disorders of female genital tract
0.000 0.045 0.955
E20-E35 Disorders of other endocrine glands
0.953 0.047 0.000
K50-K52 Noninfective enteritis and colitis
0.073 0.051 0.877
N39.3 Stress incontinence
0.000 0.051 0.949
E27 Other disorders of adrenal gland
0.949 0.051 0.000
H43 Disorders of vitreous body
0.946 0.054 0.000
E27.1 Primary adrenocortical insufficiency
0.946 0.054 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.057 0.943
K51 Ulcerative colitis
0.001 0.059 0.940
D86.9 Sarcoidosis, unspecified
0.939 0.061 0.000
H34 Retinal vascular occlusions
0.938 0.062 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.062 0.938
K51.2 Ulcerative (chronic) proctitis
0.000 0.064 0.936
N87 Dysplasia of cervix uteri
0.000 0.065 0.935
E70-E90 Metabolic disorders
0.934 0.066 0.000
H43.1 Vitreous haemorrhage
0.932 0.068 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.070 0.930
N85 Other noninflammatory disorders of uterus, except cervix
0.000 0.070 0.930
H47 Other disorders of optic [2nd] nerve and visual pathways
0.927 0.073 0.000
E14.3 With ophthalmic complications
0.926 0.074 0.000
L40-L45 Papulosquamous disorders
0.926 0.074 0.000
N97 Female infertility
0.000 0.076 0.924
N84 Polyp of female genital tract
0.000 0.077 0.923
N81 Female genital prolapse
0.000 0.078 0.922
I70-I79 Diseases of arteries, arterioles and capillaries
0.920 0.080 0.000
L20-L30 Dermatitis and eczema
0.920 0.080 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.920 0.080 0.000
N42.8 Other specified disorders of prostate
0.000 0.080 0.920
I73 Other peripheral vascular diseases
0.920 0.080 0.000
M60-M63 Disorders of muscles
0.920 0.080 0.000
L50-L54 Urticaria and erythema
0.920 0.080 0.000
M22 Disorders of patella
0.919 0.081 0.000
M34 Systemic sclerosis
0.919 0.081 0.000
E10.2 With renal complications
0.914 0.086 0.000
N84.1 Polyp of cervix uteri
0.000 0.088 0.912
L43 Lichen planus
0.912 0.088 0.000
I73.9 Peripheral vascular disease, unspecified
0.911 0.089 0.000
M11 Other crystal arthropathies
0.911 0.089 0.000
M31 Other necrotising vasculopathies
0.909 0.091 0.000
M10 Gout
0.909 0.091 0.000
N30 Cystitis
0.000 0.092 0.908
E10.1 With ketoacidosis
0.907 0.093 0.000
N85.2 Hypertrophy of uterus
0.000 0.095 0.905
L43.9 Lichen planus, unspecified
0.902 0.098 0.000
N41 Inflammatory diseases of prostate
0.000 0.100 0.900
R30-R39 Symptoms and signs involving the urinary system
0.000 0.101 0.899
K90 Intestinal malabsorption
0.830 0.104 0.066
E10.4 With neurological complications
0.893 0.107 0.000
M35.3 Polymyalgia rheumatica
0.892 0.108 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.000 0.108 0.892
N81.2 Incomplete uterovaginal prolapse
0.000 0.108 0.892
N42.1 Congestion and haemorrhage of prostate
0.000 0.109 0.891
N97.9 Female infertility, unspecified
0.000 0.110 0.890
N39.9 Disorder of urinary system, unspecified
0.000 0.119 0.881
N34 Urethritis and urethral syndrome
0.000 0.122 0.878
L30 Other dermatitis
0.877 0.123 0.000
H34.8 Other retinal vascular occlusions
0.876 0.124 0.000
I77 Other disorders of arteries and arterioles
0.875 0.125 0.000
K51.4 Pseudopolyposis of colon
0.000 0.133 0.867
M23.2 Derangement of meniscus due to old tear or injury
0.867 0.133 0.000
M62 Other disorders of muscle
0.866 0.134 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.866 0.134 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.863 0.137 0.000
I73.0 Raynaud's syndrome
0.861 0.139 0.000
M17.1 Other primary gonarthrosis
0.861 0.139 0.000
E78.5 Hyperlipidaemia, unspecified
0.860 0.140 0.000
H26.1 Traumatic cataract
0.860 0.140 0.000
N81.4 Uterovaginal prolapse, unspecified
0.000 0.142 0.858
N85.0 Endometrial glandular hyperplasia
0.000 0.143 0.857
R33 Retention of urine
0.000 0.145 0.855
M24 Other specific joint derangements
0.854 0.146 0.000
M23.3 Other meniscus derangements
0.851 0.149 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.153 0.847
N30.2 Other chronic cystitis
0.000 0.153 0.847
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.846 0.154 0.000
E83 Disorders of mineral metabolism
0.792 0.155 0.053
N87.0 Mild cervical dysplasia
0.000 0.155 0.845
K92 Other diseases of digestive system
0.003 0.158 0.839
M11.2 Other chondrocalcinosis
0.842 0.158 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.159 0.841
L30.9 Dermatitis, unspecified
0.840 0.160 0.000
E78.6 Lipoprotein deficiency
0.838 0.162 0.000
N36 Other disorders of urethra
0.000 0.164 0.836
E78.9 Disorder of lipoprotein metabolism, unspecified
0.836 0.164 0.000
L10-L14 Bullous disorders
0.835 0.165 0.000
I70 Atherosclerosis
0.834 0.166 0.000
M31.6 Other giant cell arteritis
0.833 0.167 0.000
Chapter IX Diseases of the circulatory system
0.832 0.168 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.169 0.831
H27 Other disorders of lens
0.831 0.169 0.000
K92.0 Haematemesis
0.000 0.170 0.830
L52 Erythema nodosum
0.830 0.170 0.000
M22.3 Other derangements of patella
0.829 0.171 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.826 0.174 0.000
I74 Arterial embolism and thrombosis
0.825 0.175 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.825 0.175 0.000
H26.4 After-cataract
0.823 0.177 0.000
H47.3 Other disorders of optic disk
0.823 0.177 0.000
M70-M79 Other soft tissue disorders
0.822 0.178 0.000
H47.2 Optic atrophy
0.820 0.180 0.000
M10.0 Idiopathic gout
0.820 0.180 0.000
N41.0 Acute prostatitis
0.000 0.184 0.816
M72 Fibroblastic disorders
0.814 0.186 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.811 0.189 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.810 0.190 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.809 0.191 0.000
M06 Other rheumatoid arthritis
0.808 0.192 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.808 0.192 0.000
D83 Common variable immunodeficiency
0.807 0.193 0.000
I77.1 Stricture of artery
0.806 0.194 0.000
M62.8 Other specified disorders of muscle
0.805 0.195 0.000
I77.6 Arteritis, unspecified
0.803 0.197 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.803 0.197 0.000
N30.3 Trigonitis
0.000 0.198 0.802
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.801 0.199 0.000
E78.1 Pure hyperglyceridaemia
0.801 0.199 0.000
H35 Other retinal disorders
0.799 0.201 0.000
N46 Male infertility
0.000 0.202 0.798
D86.8 Sarcoidosis of other and combined sites
0.798 0.202 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.203 0.797
D80 Immunodeficiency with predominantly antibody defects
0.796 0.204 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.792 0.208 0.000
H31 Other disorders of choroid
0.791 0.209 0.000
E10.5 With peripheral circulatory complications
0.789 0.211 0.000
M34.1 CR(E)ST syndrome
0.789 0.211 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.213 0.787
T39.1 4-Aminophenol derivatives
0.000 0.216 0.784
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.784 0.216 0.000
N30.8 Other cystitis
0.000 0.217 0.783
K50 Crohn's disease [regional enteritis]
0.004 0.218 0.778
M65-M68 Disorders of synovium and tendon
0.780 0.220 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.220 0.780
M15 Polyarthrosis
0.778 0.222 0.000
M34.9 Systemic sclerosis, unspecified
0.778 0.222 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.777 0.223 0.000
D55-D59 Haemolytic anaemias
0.777 0.223 0.000
N42.0 Calculus of prostate
0.000 0.225 0.775
E10.8 With unspecified complications
0.774 0.226 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.229 0.771
M23.6 Other spontaneous disruption of ligament(s) of knee
0.770 0.230 0.000
D84 Other immunodeficiencies
0.770 0.230 0.000
M22.2 Patellofemoral disorders
0.769 0.231 0.000
M23.9 Internal derangement of knee, unspecified
0.769 0.231 0.000
N85.6 Intra-uterine synechiae
0.000 0.234 0.766
E07 Other disorders of thyroid
0.766 0.234 0.000
H53-H54 Visual disturbances and blindness
0.766 0.234 0.000
E83.5 Disorders of calcium metabolism
0.763 0.235 0.002
H30 Chorioretinal inflammation
0.765 0.235 0.000
K46 Unspecified abdominal hernia
0.000 0.235 0.764
L80-L99 Other disorders of the skin and subcutaneous tissue
0.764 0.236 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.764 0.236 0.000
H34.2 Other retinal artery occlusions
0.764 0.236 0.000
L27 Dermatitis due to substances taken internally
0.763 0.237 0.000
N84.9 Polyp of female genital tract, unspecified
0.000 0.238 0.762
H35.8 Other specified retinal disorders
0.762 0.238 0.000
H46 Optic neuritis
0.762 0.238 0.000
N34.2 Other urethritis
0.000 0.238 0.762
N87.1 Moderate cervical dysplasia
0.000 0.239 0.761
N91 Absent, scanty and rare menstruation
0.000 0.242 0.758
N36.2 Urethral caruncle
0.000 0.242 0.758
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.243 0.757
M10.9 Gout, unspecified
0.756 0.244 0.000
M33 Dermatopolymyositis
0.755 0.245 0.000
E73 Lactose intolerance
0.755 0.245 0.000
K92.1 Melaena
0.000 0.245 0.755
L28 Lichen simplex chronicus and prurigo
0.754 0.246 0.000
N97.1 Female infertility of tubal origin
0.000 0.246 0.754
M06.9 Rheumatoid arthritis, unspecified
0.753 0.247 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.753 0.247 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.722 0.249 0.029
E20 Hypoparathyroidism
0.751 0.249 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.250 0.750
E11 Non-insulin-dependent diabetes mellitus
0.750 0.250 0.000
L50 Urticaria
0.749 0.250 0.000
E06 Thyroiditis
0.748 0.251 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.747 0.253 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.747 0.253 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.745 0.255 0.000
E78.4 Other hyperlipidaemia
0.745 0.255 0.000
M07 Psoriatic and enteropathic arthropathies
0.742 0.258 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.259 0.741
T42.4 Benzodiazepines
0.000 0.259 0.741
E84 Cystic fibrosis
0.740 0.259 0.000
L53 Other erythematous conditions
0.740 0.260 0.000
E10.0 With coma
0.740 0.260 0.000
N32.1 Vesicointestinal fistula
0.000 0.260 0.740
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.261 0.739
E16.1 Other hypoglycaemia
0.736 0.264 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.735 0.265 0.000
M35.7 Hypermobility syndrome
0.734 0.266 0.000
E10.6 With other specified complications
0.734 0.266 0.000
K92.9 Disease of digestive system, unspecified
0.001 0.267 0.732
M23.1 Discoid meniscus (congenital)
0.732 0.268 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.732 0.268 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.732 0.268 0.000
N41.1 Chronic prostatitis
0.000 0.271 0.729
M12 Other specific arthropathies
0.728 0.272 0.000
N45 Orchitis and epididymitis
0.000 0.272 0.728
M00-M03 Infectious arthropathies
0.727 0.273 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.727 0.273 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.726 0.274 0.000
H43.2 Crystalline deposits in vitreous body
0.725 0.275 0.000
M22.8 Other disorders of patella
0.724 0.276 0.000
M11.9 Crystal arthropathy, unspecified
0.724 0.276 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.000 0.277 0.723
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.278 0.722
T39.0 Salicylates
0.000 0.278 0.722
N20-N23 Urolithiasis
0.000 0.279 0.721
E13 Other specified diabetes mellitus
0.721 0.279 0.000
M35.1 Other overlap syndromes
0.719 0.281 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.281 0.719
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.281 0.718
M13 Other arthritis
0.716 0.283 0.001
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.283 0.717
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.000 0.283 0.717
N33 Bladder disorders in diseases classified elsewhere
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.283 0.717
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.284 0.716
N44 Torsion of testis
0.000 0.284 0.716
K44.1 Diaphragmatic hernia with gangrene
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.715 0.284 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
N81.9 Female genital prolapse, unspecified
0.000 0.285 0.715
H26.3 Drug-induced cataract
0.714 0.285 0.000
E03.8 Other specified hypothyroidism
0.714 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.286 0.000
H43.9 Disorder of vitreous body, unspecified
0.714 0.286 0.000
H47.1 Papilloedema, unspecified
0.714 0.286 0.000
M14 Arthropathies in other diseases classified elsewhere
0.713 0.287 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.711 0.289 0.000
I70.0 Atherosclerosis of aorta
0.710 0.290 0.000
N42.2 Atrophy of prostate
0.000 0.290 0.710
M62.6 Muscle strain
0.709 0.291 0.000
D82 Immunodeficiency associated with other major defects
0.709 0.291 0.000
D81 Combined immunodeficiencies
0.709 0.291 0.000
H43.8 Other disorders of vitreous body
0.708 0.292 0.000
N42.3 Dysplasia of prostate
0.000 0.292 0.708
E74 Other disorders of carbohydrate metabolism
0.707 0.292 0.000
M34.8 Other forms of systemic sclerosis
0.707 0.293 0.000
L23 Allergic contact dermatitis
0.707 0.293 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.109 0.294 0.597
M23.4 Loose body in knee
0.706 0.294 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.706 0.294 0.000
R35 Polyuria
0.000 0.294 0.706
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
N81.3 Complete uterovaginal prolapse
0.000 0.297 0.703
E50-E64 Other nutritional deficiencies
0.703 0.297 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.297 0.703
N32.2 Vesical fistula, not elsewhere classified
0.000 0.297 0.703
M17.5 Other secondary gonarthrosis
0.703 0.297 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.702 0.297 0.000
D86.3 Sarcoidosis of skin
0.702 0.298 0.000
I77.8 Other specified disorders of arteries and arterioles
0.700 0.300 0.000
M23.0 Cystic meniscus
0.699 0.301 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.699 0.301 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.699 0.301 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.698 0.302 0.000
Q50-Q56 Congenital malformations of genital organs
0.698 0.302 0.000
R32 Unspecified urinary incontinence
0.000 0.304 0.696
M24.1 Other articular cartilage disorders
0.695 0.305 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.695 0.305 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.695 0.305 0.000
E14.1 With ketoacidosis
0.694 0.306 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.694 0.306 0.000
K90.9 Intestinal malabsorption, unspecified
0.665 0.306 0.029
N34.3 Urethral syndrome, unspecified
0.000 0.306 0.693
D86.0 Sarcoidosis of lung
0.693 0.307 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.692 0.308 0.000
E05.8 Other thyrotoxicosis
0.691 0.308 0.000
M35.2 Behcet's disease
0.691 0.309 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.690 0.310 0.000
H27.0 Aphakia
0.690 0.310 0.000
E14.9 Without complications
0.689 0.311 0.000
D61 Other aplastic anaemias
0.688 0.312 0.000
M25 Other joint disorders, not elsewhere classified
0.687 0.313 0.000
M67 Other disorders of synovium and tendon
0.687 0.313 0.000
E14.8 With unspecified complications
0.687 0.313 0.000
E14.7 With multiple complications
0.687 0.313 0.000
E14.6 With other specified complications
0.687 0.313 0.000
E14.5 With peripheral circulatory complications
0.687 0.313 0.000
E14.4 With neurological complications
0.687 0.313 0.000
E14.2 Withrenal complications
0.687 0.313 0.000
E14.0 With coma
0.687 0.313 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.685 0.315 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.317 0.000
E32 Diseases of thymus
0.683 0.317 0.000
E31 Polyglandular dysfunction
0.683 0.317 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.317 0.000
E25 Adrenogenital disorders
0.683 0.317 0.000
Chapter XX External causes of morbidity and mortality
0.682 0.318 0.000
D64.8 Other specified anaemias
0.682 0.318 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.681 0.319 0.000
L13 Other bullous disorders
0.681 0.319 0.000
E27.5 Adrenomedullary hyperfunction
0.680 0.320 0.000
E27.0 Other adrenocortical overactivity
0.680 0.320 0.000
E11.5 With peripheral circulatory complications
0.680 0.320 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.321 0.679
E24 Cushing's syndrome
0.679 0.321 0.000
L94 Other localised connective tissue disorders
0.679 0.321 0.000
H43.0 Vitreous prolapse
0.678 0.322 0.000
D83.9 Common variable immunodeficiency, unspecified
0.678 0.322 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.001 0.325 0.674
K51.8 Other ulcerative colitis
0.000 0.326 0.674
L30.8 Other specified dermatitis
0.674 0.326 0.000
H34.9 Retinal vascular occlusion, unspecified
0.673 0.327 0.000
H34.0 Transient retinal artery occlusion
0.673 0.327 0.000
M24.2 Disorder of ligament
0.671 0.329 0.000
H44 Disorders of globe
0.671 0.329 0.000
E11.3 With ophthalmic complications
0.671 0.329 0.000
N30.0 Acute cystitis
0.000 0.330 0.670
M23.30 Other meniscus derangements (Multiple sites)
0.670 0.330 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.670 0.330 0.000
E79 Disorders of purine and pyrimidine metabolism
0.669 0.331 0.000
E77 Disorders of glycoprotein metabolism
0.669 0.331 0.000
E76 Disorders of glycosaminoglycan metabolism
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
E72 Other disorders of amino-acid metabolism
0.669 0.331 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.669 0.331 0.000
E70 Disorders of aromatic amino-acid metabolism
0.669 0.331 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.669 0.331 0.000
M86-M90 Other osteopathies
0.669 0.331 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.668 0.331 0.000
E27.2 Addisonian crisis
0.668 0.332 0.000
K50.8 Other Crohn's disease
0.002 0.332 0.666
M62.80 Other specified disorders of muscle (Multiple sites)
0.667 0.333 0.000
I70.8 Atherosclerosis of other arteries
0.667 0.333 0.000
N85.5 Inversion of uterus
0.000 0.333 0.667
N85.3 Subinvolution of uterus
0.000 0.333 0.667
N84.8 Polyp of other parts of female genital tract
0.000 0.334 0.666
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.335 0.665
H47.7 Disorder of visual pathways, unspecified
0.665 0.335 0.000
H47.6 Disorders of visual cortex
0.665 0.335 0.000
H47.5 Disorders of other visual pathways
0.665 0.335 0.000
H47.4 Disorders of optic chiasm
0.665 0.335 0.000
I78 Diseases of capillaries
0.665 0.335 0.000
L44 Other papulosquamous disorders
0.664 0.336 0.000
L41 Parapsoriasis
0.664 0.336 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.664 0.336 0.000
N97.8 Female infertility of other origin
0.000 0.337 0.663
N97.4 Female infertility associated with male factors
0.000 0.337 0.663
N97.3 Female infertility of cervical origin
0.000 0.337 0.663
N97.2 Female infertility of uterine origin
0.000 0.337 0.663
N97.0 Female infertility associated with anovulation
0.000 0.337 0.663
M13.0 Polyarthritis, unspecified
0.662 0.337 0.000
H34.1 Central retinal artery occlusion
0.661 0.339 0.000
H21 Other disorders of iris and ciliary body
0.660 0.340 0.000
L25 Unspecified contact dermatitis
0.660 0.340 0.000
L24 Irritant contact dermatitis
0.660 0.340 0.000
L26 Exfoliative dermatitis
0.660 0.340 0.000
L22 Diaper [napkin] dermatitis
0.660 0.340 0.000
E78.3 Hyperchylomicronaemia
0.660 0.340 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.659 0.340 0.000
M61 Calcification and ossification of muscle
0.659 0.340 0.000
L54 Erythema in diseases classified elsewhere
0.659 0.341 0.000
M22.1 Recurrent subluxation of patella
0.659 0.341 0.000
M22.9 Disorder of patella, unspecified
0.659 0.341 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.659 0.341 0.000
M34.0 Progressive systemic sclerosis
0.659 0.341 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.659 0.341 0.000
E27.9 Disorder of adrenal gland, unspecified
0.658 0.342 0.000
N84.3 Polyp of vulva
0.000 0.342 0.657
D86.1 Sarcoidosis of lymph nodes
0.656 0.344 0.000
H35.0 Background retinopathy and retinal vascular changes
0.655 0.345 0.000
M22.0 Recurrent dislocation of patella
0.655 0.345 0.000
M76 Enthesopathies of lower limb, excluding foot
0.655 0.345 0.000
L43.8 Other lichen planus
0.654 0.346 0.000
E40-E46 Malnutrition
0.654 0.346 0.000
L43.3 Subacute (active) lichen planus
0.654 0.346 0.000
L43.2 Lichenoid drug reaction
0.654 0.346 0.000
L43.1 Bullous lichen planus
0.654 0.346 0.000
L43.0 Hypertrophic lichen planus
0.654 0.346 0.000
E88 Other metabolic disorders
0.653 0.346 0.000
M11.8 Other specified crystal arthropathies
0.653 0.347 0.000
M11.1 Familial chondrocalcinosis
0.653 0.347 0.000
M11.0 Hydroxyapatite deposition disease
0.653 0.347 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.653 0.347 0.000
H54 Blindness and low vision
0.653 0.347 0.000
M31.9 Necrotising vasculopathy, unspecified
0.652 0.348 0.000
M31.8 Other specified necrotising vasculopathies
0.652 0.348 0.000
M31.7 Microscopic polyangiitis
0.652 0.348 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.652 0.348 0.000
M31.2 Lethal midline granuloma
0.652 0.348 0.000
M31.1 Thrombotic microangiopathy
0.652 0.348 0.000
M31.0 Hypersensitivity angiitis
0.652 0.348 0.000
M10.4 Other secondary gout
0.651 0.348 0.000
M10.3 Gout due to impairment of renal function
0.651 0.348 0.000
M10.2 Drug-induced gout
0.651 0.348 0.000
M10.1 Lead-induced gout
0.651 0.348 0.000
L50.0 Allergic urticaria
0.651 0.349 0.000
L12 Pemphigoid
0.651 0.349 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.650 0.350 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.648 0.352 0.000
M10.06 Idiopathic gout (Lower leg)
0.647 0.353 0.000
L51 Erythema multiforme
0.647 0.353 0.000
I77.2 Rupture of artery
0.646 0.354 0.000
N32.8 Other specified disorders of bladder
0.000 0.355 0.645
N41.3 Prostatocystitis
0.000 0.355 0.645
N41.2 Abscess of prostate
0.000 0.355 0.645
N20 Calculus of kidney and ureter
0.000 0.355 0.645
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.356 0.644
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.356 0.644

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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