TreeWAS – Variant ID: rs7756516

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E10.9 Without complications	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
E16.2 Hypoglycaemia, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
E10.1 With ketoacidosis	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E14 Unspecified diabetes mellitus	0.000	0.000	1.000
E16 Other disorders of pancreatic internal secretion	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.000	1.000
M07 Psoriatic and enteropathic arthropathies	0.999	0.001	0.000
M07.3 Other psoriatic arthropathies	0.999	0.001	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.996	0.004	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.995	0.005	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.007	0.993
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.007	0.993
E10.4 With neurological complications	0.000	0.008	0.992
E14.9 Without complications	0.000	0.008	0.992
E00-E07 Disorders of thyroid gland	0.000	0.008	0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.990	0.010	0.000
M06.3 Rheumatoid nodule	0.990	0.010	0.000
E14.3 With ophthalmic complications	0.000	0.014	0.986
E10.2 With renal complications	0.000	0.023	0.977
C44.7 Skin of lower limb, including hip	0.960	0.040	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.951	0.049	0.000
M06.0 Seronegative rheumatoid arthritis	0.949	0.051	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.064	0.936
E40-E46 Malnutrition	0.000	0.066	0.934
C44 Other malignant neoplasms of skin	0.924	0.076	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.080	0.920
G37 Other demyelinating diseases of central nervous system	0.000	0.080	0.920
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.907	0.093	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.905	0.095	0.000
E10.5 With peripheral circulatory complications	0.000	0.096	0.904
C43 Malignant melanoma of skin	0.902	0.098	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.113	0.887
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.886	0.114	0.000
M06.34 Rheumatoid nodule (Hand)	0.886	0.114	0.000
C44.3 Skin of other and unspecified parts of face	0.882	0.118	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.880	0.120	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.876	0.124	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.874	0.125	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.133	0.867
C43.6 Malignant melanoma of upper limb, including shoulder	0.863	0.137	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.862	0.138	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.862	0.138	0.000
E50-E64 Other nutritional deficiencies	0.000	0.139	0.861
R31 Unspecified haematuria	0.861	0.139	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.859	0.141	0.000
K90 Intestinal malabsorption	0.000	0.148	0.852
E14.8 With unspecified complications	0.000	0.153	0.847
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.837	0.163	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.835	0.165	0.000
M06.4 Inflammatory polyarthropathy	0.829	0.171	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.827	0.173	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.177	0.823
C44.5 Skin of trunk	0.823	0.177	0.000
L40.1 Generalised pustular psoriasis	0.823	0.177	0.000
E14.2 Withrenal complications	0.000	0.184	0.816
E10.8 With unspecified complications	0.000	0.190	0.810
K90.9 Intestinal malabsorption, unspecified	0.000	0.192	0.808
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.806	0.194	0.000
E14.6 With other specified complications	0.000	0.195	0.805
M06.33 Rheumatoid nodule (Forearm)	0.800	0.200	0.000
C43.4 Malignant melanoma of scalp and neck	0.799	0.201	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.797	0.203	0.000
E10.0 With coma	0.000	0.207	0.792
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.791	0.209	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.210	0.790
M07.36 Other psoriatic arthropathies (Lower leg)	0.786	0.214	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.786	0.214	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.786	0.214	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.784	0.216	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.783	0.217	0.000
E10.7 With multiple complications	0.000	0.218	0.782
C43.3 Malignant melanoma of other and unspecified parts of face	0.776	0.224	0.000
L40.8 Other psoriasis	0.776	0.224	0.000
M05.8 Other seropositive rheumatoid arthritis	0.775	0.225	0.000
M05.2 Rheumatoid vasculitis	0.774	0.226	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.772	0.228	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.770	0.230	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.231	0.769
M07.34 Other psoriatic arthropathies (Hand)	0.769	0.231	0.000
M05.1 Rheumatoid lung disease	0.767	0.233	0.000
E55 Vitamin D deficiency	0.000	0.235	0.765
M07.31 Other psoriatic arthropathies (Shoulder region)	0.760	0.240	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.758	0.242	0.000
E10.6 With other specified complications	0.000	0.243	0.757
M06.30 Rheumatoid nodule (Multiple sites)	0.755	0.245	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.755	0.245	0.000
L40.0 Psoriasis vulgaris	0.755	0.245	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.746	0.254	0.000
M08 Juvenile arthritis	0.739	0.261	0.000
M14 Arthropathies in other diseases classified elsewhere	0.732	0.268	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.730	0.270	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.280	0.720
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.283	0.717
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.283	0.717
E16.4 Abnormal secretion of gastrin	0.000	0.283	0.717
E16.3 Increased secretion of glucagon	0.000	0.283	0.717
E14.7 With multiple complications	0.000	0.283	0.717
E14.0 With coma	0.000	0.283	0.717
E15 Nondiabetic hypoglycaemic coma	0.000	0.283	0.717
M07.5 Arthropathy in ulcerative colitis	0.716	0.283	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.716	0.283	0.000
M07.2 Psoriatic spondylitis	0.716	0.283	0.000
M07.1 Arthritis mutilans	0.716	0.283	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.716	0.283	0.000
M07.38 Other psoriatic arthropathies (Other)	0.716	0.284	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.716	0.284	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.716	0.284	0.000
G36 Other acute disseminated demyelination	0.000	0.284	0.715
E05.5 Thyroid crisis or storm	0.000	0.288	0.712
E05.4 Thyrotoxicosis factitia	0.000	0.288	0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.288	0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.289	0.711
E00 Congenital iodine-deficiency syndrome	0.000	0.289	0.711
E14.5 With peripheral circulatory complications	0.000	0.290	0.710
M06.39 Rheumatoid nodule (Site unspecified)	0.710	0.290	0.000
M06.38 Rheumatoid nodule (Other)	0.710	0.290	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.710	0.290	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.710	0.290	0.000
C43.0 Malignant melanoma of lip	0.706	0.294	0.000
L40-L45 Papulosquamous disorders	0.701	0.298	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.701	0.299	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.303	0.697
M06.8 Other specified rheumatoid arthritis	0.694	0.306	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.693	0.307	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.691	0.309	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.309	0.691
M07.6 Other enteropathic arthropathies	0.686	0.313	0.000
M11 Other crystal arthropathies	0.682	0.318	0.000
L40.3 Pustulosis palmaris et plantaris	0.681	0.319	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.681	0.319	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.681	0.319	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.681	0.319	0.000
L40.4 Guttate psoriasis	0.680	0.320	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.330	0.670
E45 Retarded development following protein-energy malnutrition	0.000	0.330	0.670
E43 Unspecified severe protein-energy malnutrition	0.000	0.330	0.670
E42 Marasmic kwashiorkor	0.000	0.330	0.670
E41 Nutritional marasmus	0.000	0.330	0.670
E40 Kwashiorkor	0.000	0.330	0.670
E58 Dietary calcium deficiency	0.000	0.333	0.667
M06.04 Seronegative rheumatoid arthritis (Hand)	0.665	0.335	0.000
C44.8 Overlapping lesion of skin	0.663	0.337	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.662	0.338	0.000
E14.1 With ketoacidosis	0.000	0.338	0.661
G37.5 Concentric sclerosis [Balo]	0.000	0.340	0.660
G37.4 Subacute necrotising myelitis	0.000	0.340	0.660
G37.2 Central pontine myelinolysis	0.000	0.340	0.660
G37.1 Central demyelination of corpus callosum	0.000	0.340	0.660
G37.0 Diffuse sclerosis	0.000	0.340	0.660
L57.0 Actinic keratosis	0.653	0.347	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.349	0.650
C43.8 Overlapping malignant melanoma of skin	0.647	0.353	0.000
E16.1 Other hypoglycaemia	0.000	0.355	0.645
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.367	0.633
E07 Other disorders of thyroid	0.000	0.368	0.632
E61 Deficiency of other nutrient elements	0.000	0.370	0.630
M06.46 Inflammatory polyarthropathy (Lower leg)	0.628	0.371	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.627	0.373	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.382	0.618
E63 Other nutritional deficiencies	0.000	0.382	0.618
E50 Vitamin A deficiency	0.000	0.382	0.618
E60 Dietary zinc deficiency	0.000	0.382	0.618
E59 Dietary selenium deficiency	0.000	0.382	0.618
E54 Ascorbic acid deficiency	0.000	0.382	0.618
E52 Niacin deficiency [pellagra]	0.000	0.382	0.618
K90.3 Pancreatic steatorrhoea	0.000	0.389	0.611
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.389	0.611
K90.1 Tropical sprue	0.000	0.389	0.611
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.610	0.390	0.000
E13 Other specified diabetes mellitus	0.000	0.391	0.609
C44.0 Skin of lip	0.606	0.394	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.606	0.394	0.000
E53 Deficiency of other B group vitamins	0.000	0.395	0.605
C43.2 Malignant melanoma of ear and external auricular canal	0.605	0.395	0.000
M12 Other specific arthropathies	0.602	0.397	0.000
E05.8 Other thyrotoxicosis	0.000	0.398	0.602
M14.6 Neuropathic arthropathy	0.601	0.398	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.601	0.399	0.000
K90.8 Other intestinal malabsorption	0.000	0.402	0.597
E51 Thiamine deficiency	0.000	0.403	0.597
C43.1 Malignant melanoma of eyelid, including canthus	0.596	0.404	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.594	0.406	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.594	0.406	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.594	0.406	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.594	0.406	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.594	0.406	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.594	0.406	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.594	0.406	0.000
C44.4 Skin of scalp and neck	0.594	0.406	0.000
L42 Pityriasis rosea	0.585	0.415	0.000
E14.4 With neurological complications	0.000	0.424	0.575
E56 Other vitamin deficiencies	0.000	0.429	0.571
M05.20 Rheumatoid vasculitis (Multiple sites)	0.562	0.437	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.560	0.439	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.442	0.558
M05.88 Other seropositive rheumatoid arthritis (Other)	0.556	0.444	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.556	0.444	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.556	0.444	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.556	0.444	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.556	0.444	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.556	0.444	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.556	0.444	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.556	0.444	0.000
M05.28 Rheumatoid vasculitis (Other)	0.555	0.445	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.555	0.445	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.555	0.445	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.555	0.445	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.555	0.445	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.555	0.445	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.555	0.445	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.555	0.445	0.000
M08.0 Juvenile rheumatoid arthritis	0.552	0.448	0.000
M05.18 Rheumatoid lung disease (Other)	0.550	0.450	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.550	0.450	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.550	0.450	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.550	0.450	0.000
M05.14 Rheumatoid lung disease (Hand)	0.550	0.450	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.550	0.450	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.550	0.450	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.550	0.450	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.550	0.450	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.549	0.451	0.000
E55.0 Rickets, active	0.000	0.451	0.549
C43.9 Malignant melanoma of skin, unspecified	0.549	0.451	0.000
M11.9 Crystal arthropathy, unspecified	0.541	0.459	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.530	0.470	0.000
M08.9 Juvenile arthritis, unspecified	0.530	0.470	0.000
M08.8 Other juvenile arthritis	0.530	0.470	0.000
M08.4 Pauciarticular juvenile arthritis	0.530	0.470	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.530	0.470	0.000
M08.2 Juvenile arthritis with systemic onset	0.530	0.470	0.000
M08.1 Juvenile ankylosing spondylitis	0.530	0.470	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.524	0.475	0.000
M14.4 Arthropathy in amyloidosis	0.524	0.475	0.000
M14.3 Lipoid dermatoarthritis	0.524	0.475	0.000
M14.2 Diabetic arthropathy	0.524	0.475	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.524	0.475	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.524	0.475	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.514	0.486	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.514	0.486	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.514	0.486	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.514	0.486	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.514	0.486	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.514	0.486	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.514	0.486	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.514	0.486	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.514	0.486	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.514	0.486	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.514	0.486	0.000
M07.18 Arthritis mutilans (Other)	0.514	0.486	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.514	0.486	0.000
M07.16 Arthritis mutilans (Lower leg)	0.514	0.486	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.514	0.486	0.000
M07.14 Arthritis mutilans (Hand)	0.514	0.486	0.000
M07.13 Arthritis mutilans (Forearm)	0.514	0.486	0.000
M07.12 Arthritis mutilans (Upper arm)	0.514	0.486	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.514	0.486	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.514	0.486	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.514	0.486	0.000
M07.28 Psoriatic spondylitis (Other)	0.514	0.486	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.514	0.486	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.514	0.486	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.514	0.486	0.000
M07.24 Psoriatic spondylitis (Hand)	0.514	0.486	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.514	0.486	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.514	0.486	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.514	0.486	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.514	0.486	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.514	0.486	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.514	0.486	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.514	0.486	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.514	0.486	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.514	0.486	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.514	0.486	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.514	0.486	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.514	0.486	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.514	0.486	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.514	0.486	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.514	0.486	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.514	0.486	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.514	0.486	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.514	0.486	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.514	0.486	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.514	0.486	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.514	0.486	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.514	0.486	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.514	0.486	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.514	0.486	0.000
C43.5 Malignant melanoma of trunk	0.514	0.486	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.487	0.513
G36.8 Other specified acute disseminated demyelination	0.000	0.487	0.513
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.487	0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.490	0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.490	0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.490	0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.490	0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.490	0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.490	0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.490	0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.490	0.510
L44 Other papulosquamous disorders	0.509	0.490	0.000
L41 Parapsoriasis	0.507	0.493	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.503	0.497	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.498	0.502	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.498	0.502	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.498	0.502	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.498	0.502	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.498	0.502	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.498	0.502	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.498	0.502	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.498	0.502	0.000
M07.68 Other enteropathic arthropathies (Other)	0.492	0.508	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.492	0.508	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.492	0.508	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.492	0.508	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.492	0.508	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.492	0.508	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.492	0.508	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.492	0.508	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.492	0.508	0.000
M11.1 Familial chondrocalcinosis	0.489	0.511	0.000
M11.0 Hydroxyapatite deposition disease	0.489	0.511	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.487	0.513	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.487	0.513	0.000
E06 Thyroiditis	0.001	0.514	0.485
M11.8 Other specified crystal arthropathies	0.484	0.516	0.000
E61.2 Magnesium deficiency	0.000	0.518	0.482
E44.1 Mild protein-energy malnutrition	0.000	0.520	0.480
E44.0 Moderate protein-energy malnutrition	0.000	0.520	0.480
L57.4 Cutis laxa senilis	0.473	0.527	0.000
L57.5 Actinic granuloma	0.466	0.534	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.462	0.538	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.459	0.540	0.001
M10 Gout	0.459	0.541	0.000
E07.8 Other specified disorders of thyroid	0.000	0.544	0.456
E07.1 Dyshormogenetic goitre	0.000	0.547	0.453
E07.0 Hypersecretion of calcitonin	0.000	0.547	0.453
E53.9 Vitamin B deficiency, unspecified	0.000	0.548	0.452
E61.9 Deficiency of nutrient element, unspecified	0.000	0.548	0.452
E61.8 Deficiency of other specified nutrient elements	0.000	0.548	0.452
E61.7 Deficiency of multiple nutrient elements	0.000	0.548	0.452
E61.6 Vanadium deficiency	0.000	0.548	0.452
E61.5 Molybdenum deficiency	0.000	0.548	0.452
E61.4 Chromium deficiency	0.000	0.548	0.452
E61.3 Manganese deficiency	0.000	0.548	0.452
E61.0 Copper deficiency	0.000	0.548	0.452
M13 Other arthritis	0.450	0.550	0.000
C44.6 Skin of upper limb, including shoulder	0.447	0.553	0.000
L43 Lichen planus	0.444	0.556	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.557	0.443
E50.8 Other manifestations of vitamin A deficiency	0.000	0.557	0.443
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.557	0.443
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.557	0.443
E50.5 Vitamin A deficiency with night blindness	0.000	0.557	0.443
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.557	0.443
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.557	0.443
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.557	0.443
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.557	0.443
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.557	0.443
E63.9 Nutritional deficiency, unspecified	0.000	0.557	0.443
E63.8 Other specified nutritional deficiencies	0.000	0.557	0.443
E63.1 Imbalance of constituents of food intake	0.000	0.557	0.443
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.557	0.443
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.557	0.443
E64.8 Sequelae of other nutritional deficiencies	0.000	0.557	0.443
E64.3 Sequelae of rickets	0.000	0.557	0.443
E64.2 Sequelae of vitamin C deficiency	0.000	0.557	0.443
E64.1 Sequelae of vitamin A deficiency	0.000	0.557	0.443
E64.0 Sequelae of protein-energy malnutrition	0.000	0.557	0.443
D86.9 Sarcoidosis, unspecified	0.000	0.558	0.442
E03 Other hypothyroidism	0.001	0.561	0.438
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.439	0.561	0.000
E13.8 With unspecified complications	0.000	0.563	0.437
E13.7 With multiple complications	0.000	0.563	0.437
E13.6 With other specified complications	0.000	0.563	0.437
E13.5 With peripheral circulatory complications	0.000	0.563	0.437
E13.4 With neurological complications	0.000	0.563	0.437
E13.2 With renal complications	0.000	0.563	0.437
E13.1 With ketoacidosis	0.000	0.563	0.437
E13.0 With coma	0.000	0.563	0.437
E53.1 Pyridoxine deficiency	0.000	0.566	0.434
E53.0 Riboflavin deficiency	0.000	0.566	0.434
M12.5 Traumatic arthropathy	0.432	0.568	0.000
M12.4 Intermittent hydrarthrosis	0.432	0.568	0.000
M12.1 Kaschin-Beck disease	0.432	0.568	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.432	0.568	0.000
E61.1 Iron deficiency	0.000	0.570	0.430
E51.9 Thiamine deficiency, unspecified	0.000	0.572	0.428
E51.8 Other manifestations of thiamine deficiency	0.000	0.572	0.428
E51.1 Beriberi	0.000	0.572	0.428
M14.8 Arthropathies in other specified diseases classified elsewhere	0.425	0.574	0.000
D86 Sarcoidosis	0.000	0.576	0.424
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.418	0.582	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.413	0.587	0.000
E56.9 Vitamin deficiency, unspecified	0.000	0.591	0.409
E56.8 Deficiency of other vitamins	0.000	0.591	0.409
E56.0 Deficiency of vitamin E	0.000	0.591	0.409
E51.2 Wernicke's encephalopathy	0.000	0.593	0.407
Chapter XII Diseases of the skin and subcutaneous tissue	0.402	0.595	0.003
M12.3 Palindromic rheumatism	0.399	0.600	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.602	0.398
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.396	0.604	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.396	0.604	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.396	0.604	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.396	0.604	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.396	0.604	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.396	0.604	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.396	0.604	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.396	0.604	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.396	0.604	0.000
L57.3 Poikiloderma of Civatte	0.394	0.606	0.000
L57.2 Cutis rhomboidalis nuchae	0.394	0.606	0.000
L57.1 Actinic reticuloid	0.394	0.606	0.000
E13.3 With ophthalmic complications	0.000	0.608	0.391
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.388	0.612	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.388	0.612	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.388	0.612	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.388	0.612	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.388	0.612	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.388	0.612	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.388	0.612	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.388	0.612	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations