TreeWAS – Variant ID: rs7758736

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
D50-D53 Nutritional anaemias	0.999	0.001	0.000
D50.9 Iron deficiency anaemia, unspecified	0.999	0.001	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
D50 Iron deficiency anaemia	0.999	0.001	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.001	0.999
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
E10.1 With ketoacidosis	0.999	0.001	0.000
N00-N08 Glomerular diseases	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.998	0.002	0.000
D86 Sarcoidosis	0.998	0.002	0.000
M06 Other rheumatoid arthritis	0.000	0.002	0.998
E27 Other disorders of adrenal gland	0.998	0.002	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.998	0.002	0.000
H30-H36 Disorders of choroid and retina	0.998	0.002	0.000
E27.1 Primary adrenocortical insufficiency	0.998	0.002	0.000
D69 Purpura and other haemorrhagic conditions	0.998	0.002	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.003	0.997
E03 Other hypothyroidism	0.997	0.003	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.995	0.005	0.000
N04 Nephrotic syndrome	0.994	0.006	0.000
Chapter XIV Diseases of the genitourinary system	0.994	0.006	0.000
M05-M14 Inflammatory polyarthropathies	0.004	0.007	0.988
N08 Glomerular disorders in diseases classified elsewhere	0.992	0.008	0.000
M80-M85 Disorders of bone density and structure	0.992	0.008	0.000
E03.9 Hypothyroidism, unspecified	0.992	0.008	0.000
D86.9 Sarcoidosis, unspecified	0.992	0.008	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.992	0.008	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.991	0.009	0.000
M05 Seropositive rheumatoid arthritis	0.002	0.009	0.989
Chapter I Certain infectious and parasitic diseases	0.991	0.009	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.009	0.991
N17-N19 Renal failure	0.991	0.009	0.000
Chapter VI Diseases of the nervous system	0.990	0.010	0.000
D69.6 Thrombocytopenia, unspecified	0.989	0.011	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.012	0.988
N17 Acute renal failure	0.988	0.012	0.000
N17.9 Acute renal failure, unspecified	0.986	0.014	0.000
N04.9 Unspecified	0.986	0.014	0.000
H33 Retinal detachments and breaks	0.984	0.016	0.000
R50-R69 General symptoms and signs	0.984	0.016	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.983	0.017	0.000
E10.2 With renal complications	0.980	0.020	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.980	0.020	0.000
H36 Retinal disorders in diseases classified elsewhere	0.979	0.021	0.000
N05 Unspecified nephritic syndrome	0.978	0.022	0.000
R53 Malaise and fatigue	0.978	0.022	0.000
E14 Unspecified diabetes mellitus	0.978	0.022	0.000
R59 Enlarged lymph nodes	0.977	0.023	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.973	0.027	0.000
L50-L54 Urticaria and erythema	0.971	0.029	0.000
Chapter II Neoplasms	0.968	0.032	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.968	0.032	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.968	0.032	0.000
R59.9 Enlarged lymph nodes, unspecified	0.968	0.032	0.000
M60-M63 Disorders of muscles	0.968	0.032	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.967	0.033	0.000
G56 Mononeuropathies of upper limb	0.966	0.034	0.000
M81 Osteoporosis without pathological fracture	0.966	0.034	0.000
R63 Symptoms and signs concerning food and fluid intake	0.966	0.034	0.000
H36.0 Diabetic retinopathy	0.965	0.035	0.000
L40-L45 Papulosquamous disorders	0.965	0.035	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.963	0.037	0.000
H33.3 Retinal breaks without detachment	0.963	0.037	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.037	0.963
R63.4 Abnormal weight loss	0.963	0.037	0.000
G56.0 Carpal tunnel syndrome	0.961	0.039	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.960	0.040	0.000
L43 Lichen planus	0.960	0.040	0.000
L43.9 Lichen planus, unspecified	0.957	0.043	0.000
H06.2 Dysthyroid exophthalmos	0.955	0.045	0.000
M15-M19 Arthrosis	0.955	0.045	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.954	0.046	0.000
L10-L14 Bullous disorders	0.953	0.046	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.952	0.048	0.000
M18 Arthrosis of first carpometacarpal joint	0.950	0.050	0.000
R42 Dizziness and giddiness	0.947	0.053	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.947	0.053	0.000
H50 Other strabismus	0.945	0.055	0.000
E14.3 With ophthalmic complications	0.945	0.055	0.000
E23 Hypofunction and other disorders of pituitary gland	0.944	0.056	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.939	0.061	0.000
M81.9 Osteoporosis, unspecified	0.937	0.063	0.000
G51 Facial nerve disorders	0.935	0.065	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.935	0.065	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.934	0.066	0.000
D69.4 Other primary thrombocytopenia	0.933	0.067	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.070	0.930
M62 Other disorders of muscle	0.930	0.070	0.000
E70-E90 Metabolic disorders	0.929	0.071	0.000
N05.2 Diffuse membranous glomerulonephritis	0.929	0.071	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.928	0.072	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.928	0.072	0.000
B15-B19 Viral hepatitis	0.927	0.073	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.073	0.927
R76 Other abnormal immunological findings in serum	0.927	0.073	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.926	0.074	0.000
L13 Other bullous disorders	0.925	0.075	0.000
G59.0 Diabetic mononeuropathy	0.923	0.077	0.000
N18 Chronic renal failure	0.922	0.078	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.922	0.078	0.000
M06.3 Rheumatoid nodule	0.000	0.085	0.915
E24 Cushing's syndrome	0.914	0.086	0.000
C85.1 B-cell lymphoma, unspecified	0.914	0.086	0.000
E10.4 With neurological complications	0.913	0.087	0.000
C81 Hodgkin's disease	0.912	0.088	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.912	0.088	0.000
A30-A49 Other bacterial diseases	0.911	0.089	0.000
Chapter IX Diseases of the circulatory system	0.911	0.089	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.910	0.090	0.000
E89.0 Postprocedural hypothyroidism	0.908	0.092	0.000
G51.0 Bell's palsy	0.907	0.093	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.906	0.094	0.000
D86.0 Sarcoidosis of lung	0.906	0.094	0.000
L13.0 Dermatitis herpetiformis	0.904	0.096	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.903	0.097	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.902	0.098	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.899	0.101	0.000
M80 Osteoporosis with pathological fracture	0.897	0.103	0.000
R76.8 Other specified abnormal immunological findings in serum	0.896	0.104	0.000
M62.8 Other specified disorders of muscle	0.895	0.105	0.000
H50.9 Strabismus, unspecified	0.895	0.105	0.000
L52 Erythema nodosum	0.894	0.106	0.000
L53 Other erythematous conditions	0.892	0.108	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.892	0.108	0.000
N05.1 Focal and segmental glomerular lesions	0.892	0.108	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.891	0.109	0.000
R60 Oedema, not elsewhere classified	0.888	0.112	0.000
R47-R49 Symptoms and signs involving speech and voice	0.887	0.113	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.886	0.114	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.885	0.115	0.000
N18.3 Chronic kidney disease, stage 3	0.884	0.116	0.000
E06 Thyroiditis	0.880	0.120	0.000
A41 Other septicaemia	0.879	0.121	0.000
H49 Paralytic strabismus	0.877	0.123	0.000
R59.0 Localised enlarged lymph nodes	0.877	0.123	0.000
H05 Disorders of orbit	0.875	0.125	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.874	0.126	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.131	0.869
L51 Erythema multiforme	0.869	0.131	0.000
M82 Osteoporosis in diseases classified elsewhere	0.868	0.131	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.868	0.132	0.000
Q43 Other congenital malformations of intestine	0.865	0.135	0.000
C04 Malignant neoplasm of floor of mouth	0.863	0.137	0.000
M81.2 Osteoporosis of disuse	0.861	0.139	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.860	0.140	0.000
R46 Symptoms and signs involving appearance and behaviour	0.860	0.140	0.000
R49 Voice disturbances	0.860	0.140	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.859	0.141	0.000
C81.9 Hodgkin's disease, unspecified	0.858	0.142	0.000
C07 Malignant neoplasm of parotid gland	0.858	0.142	0.000
I74 Arterial embolism and thrombosis	0.856	0.144	0.000
C84.5 Other and unspecified T-cell lymphomas	0.855	0.145	0.000
H10-H13 Disorders of conjunctiva	0.854	0.146	0.000
I60-I69 Cerebrovascular diseases	0.854	0.146	0.000
I10-I15 Hypertensive diseases	0.851	0.149	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.850	0.150	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.850	0.150	0.000
B35-B49 Mycoses	0.850	0.150	0.000
C34 Malignant neoplasm of bronchus and lung	0.850	0.150	0.000
D73 Diseases of spleen	0.849	0.151	0.000
B25-B34 Other viral diseases	0.848	0.152	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.846	0.154	0.000
C91 Lymphoid leukaemia	0.846	0.154	0.000
M00-M03 Infectious arthropathies	0.846	0.154	0.000
Q44.6 Cystic disease of liver	0.845	0.155	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.845	0.155	0.000
M15 Polyarthrosis	0.844	0.156	0.000
D69.2 Other nonthrombocytopenic purpura	0.844	0.156	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.843	0.157	0.000
H33.0 Retinal detachment with retinal break	0.842	0.158	0.000
N04.2 Diffuse membranous glomerulonephritis	0.840	0.160	0.000
E86 Volume depletion	0.839	0.161	0.000
I12 Hypertensive renal disease	0.834	0.166	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.166	0.834
E23.2 Diabetes insipidus	0.834	0.166	0.000
R60.0 Localised oedema	0.831	0.169	0.000
R40 Somnolence, stupor and coma	0.830	0.170	0.000
N18.0 End-stage renal disease	0.830	0.170	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.827	0.173	0.000
C88 Malignant immunoproliferative diseases	0.826	0.174	0.000
H50.5 Heterophoria	0.825	0.175	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.823	0.177	0.000
B16 Acute hepatitis B	0.821	0.179	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.820	0.180	0.000
E10.0 With coma	0.819	0.180	0.000
H05.2 Exophthalmic conditions	0.819	0.181	0.000
I12.9 Hypertensive renal disease without renal failure	0.819	0.181	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.819	0.181	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.818	0.182	0.000
N04.1 Focal and segmental glomerular lesions	0.817	0.183	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.184	0.816
M60 Myositis	0.813	0.187	0.000
E23.6 Other disorders of pituitary gland	0.813	0.187	0.000
C34.3 Lower lobe, bronchus or lung	0.812	0.188	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.812	0.188	0.000
B07 Viral warts	0.811	0.189	0.000
D69.9 Haemorrhagic condition, unspecified	0.810	0.190	0.000
R71 Abnormality of red blood cells	0.810	0.190	0.000
D73.5 Infarction of spleen	0.810	0.190	0.000
E10.7 With multiple complications	0.809	0.191	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.808	0.192	0.000
E14.8 With unspecified complications	0.808	0.192	0.000
D52 Folate deficiency anaemia	0.808	0.192	0.000
E29 Testicular dysfunction	0.806	0.194	0.000
G54 Nerve root and plexus disorders	0.806	0.194	0.000
D86.3 Sarcoidosis of skin	0.806	0.194	0.000
G52 Disorders of other cranial nerves	0.805	0.195	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.804	0.196	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.804	0.196	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.197	0.803
L51.9 Erythema multiforme, unspecified	0.803	0.197	0.000
G58 Other mononeuropathies	0.802	0.198	0.000
M85 Other disorders of bone density and structure	0.802	0.198	0.000
E13 Other specified diabetes mellitus	0.800	0.200	0.000
A63.0 Anogenital (venereal) warts	0.798	0.202	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.798	0.202	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.798	0.202	0.000
R49.8 Other and unspecified voice disturbances	0.797	0.203	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.797	0.203	0.000
I77 Other disorders of arteries and arterioles	0.797	0.203	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.797	0.203	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.795	0.205	0.000
A15-A19 Tuberculosis	0.793	0.207	0.000
L53.0 Toxic erythema	0.789	0.211	0.000
B17 Other acute viral hepatitis	0.789	0.211	0.000
D51 Vitamin B12 deficiency anaemia	0.789	0.211	0.000
E28 Ovarian dysfunction	0.788	0.212	0.000
E24.9 Cushing's syndrome, unspecified	0.787	0.213	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.786	0.214	0.000
C92 Myeloid leukaemia	0.786	0.214	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.214	0.786
I63 Cerebral infarction	0.784	0.216	0.000
G56.4 Causalgia	0.784	0.216	0.000
R74 Abnormal serum enzyme levels	0.782	0.218	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.780	0.220	0.000
M82.1 Osteoporosis in endocrine disorders	0.780	0.220	0.000
E23.7 Disorder of pituitary gland, unspecified	0.780	0.220	0.000
E78.2 Mixed hyperlipidaemia	0.779	0.221	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.779	0.221	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.779	0.221	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.779	0.221	0.000
C04.9 Floor of mouth, unspecified	0.778	0.222	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.778	0.222	0.000
L53.9 Erythematous condition, unspecified	0.778	0.222	0.000
G11 Hereditary ataxia	0.776	0.224	0.000
C03 Malignant neoplasm of gum	0.775	0.225	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.226	0.774
I95-I99 Other and unspecified disorders of the circulatory system	0.772	0.227	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.772	0.228	0.000
D82 Immunodeficiency associated with other major defects	0.770	0.230	0.000
M40-M43 Deforming dorsopathies	0.769	0.231	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.769	0.231	0.000
E14.1 With ketoacidosis	0.768	0.232	0.000
E14.2 Withrenal complications	0.768	0.232	0.000
H33.4 Traction detachment of retina	0.768	0.232	0.000
E10.8 With unspecified complications	0.768	0.232	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.767	0.233	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.765	0.234	0.000
H31 Other disorders of choroid	0.765	0.235	0.000
G56.1 Other lesions of median nerve	0.765	0.235	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.765	0.235	0.000
R49.0 Dysphonia	0.765	0.235	0.000
R46.2 Strange and inexplicable behaviour	0.764	0.236	0.000
D89.1 Cryoglobulinaemia	0.764	0.236	0.000
E24.0 Pituitary-dependent Cushing's disease	0.764	0.236	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.764	0.236	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.763	0.237	0.000
D86.8 Sarcoidosis of other and combined sites	0.762	0.238	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.239	0.761
M91-M94 Chondropathies	0.761	0.239	0.000
C80 Malignant neoplasm without specification of site	0.761	0.239	0.000
E03.8 Other specified hypothyroidism	0.761	0.239	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.761	0.239	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.761	0.239	0.000
H11 Other disorders of conjunctiva	0.760	0.240	0.000
C84.0 Mycosis fungoides	0.760	0.240	0.000
D62 Acute posthaemorrhagic anaemia	0.759	0.241	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.758	0.242	0.000
H34 Retinal vascular occlusions	0.757	0.243	0.000
C34.2 Middle lobe, bronchus or lung	0.756	0.244	0.000
R63.3 Feeding difficulties and mismanagement	0.756	0.244	0.000
M83 Adult osteomalacia	0.756	0.244	0.000
H33.1 Retinoschisis and retinal cysts	0.755	0.245	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.754	0.246	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.753	0.247	0.000
H33.2 Serous retinal detachment	0.752	0.248	0.000
R44.1 Visual hallucinations	0.752	0.248	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.752	0.248	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.248	0.751
E27.3 Drug-induced adrenocortical insufficiency	0.750	0.250	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.750	0.250	0.000
H50.0 Convergent concomitant strabismus	0.750	0.250	0.000
B00 Herpesviral [herpes simplex] infections	0.749	0.251	0.000
B18 Chronic viral hepatitis	0.747	0.253	0.000
I77.1 Stricture of artery	0.746	0.254	0.000
M14 Arthropathies in other diseases classified elsewhere	0.003	0.255	0.742
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.745	0.255	0.000
H49.1 Fourth [trochlear] nerve palsy	0.744	0.256	0.000
B25 Cytomegaloviral disease	0.743	0.257	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.257	0.743
N17.0 Acute renal failure with tubular necrosis	0.743	0.257	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.742	0.258	0.000
E04 Other non-toxic goitre	0.742	0.258	0.000
T39.1 4-Aminophenol derivatives	0.000	0.259	0.741
C02.9 Tongue, unspecified	0.741	0.259	0.000
G53.0 Postzoster neuralgia	0.740	0.260	0.000
E07 Other disorders of thyroid	0.739	0.261	0.000
Q60-Q64 Congenital malformations of the urinary system	0.738	0.262	0.000
R86 Abnormal findings in specimens from male genital organs	0.738	0.262	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.262	0.738
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.738	0.262	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.736	0.264	0.000
H49.2 Sixth [abducent] nerve palsy	0.736	0.264	0.000
C34.8 Overlapping lesion of bronchus and lung	0.735	0.265	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.735	0.265	0.000
Q43.8 Other specified congenital malformations of intestine	0.732	0.268	0.000
Q43.0 Meckel's diverticulum	0.732	0.268	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.268	0.732
H50.8 Other specified strabismus	0.732	0.268	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.268	0.732
A80-A89 Viral infections of the central nervous system	0.731	0.268	0.000
M86-M90 Other osteopathies	0.731	0.269	0.000
I74.8 Embolism and thrombosis of other arteries	0.731	0.269	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.731	0.269	0.000
D84 Other immunodeficiencies	0.730	0.270	0.000
H30 Chorioretinal inflammation	0.729	0.270	0.000
C05 Malignant neoplasm of palate	0.729	0.270	0.000
E40-E46 Malnutrition	0.729	0.271	0.000
B02 Zoster [herpes zoster]	0.729	0.271	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.729	0.271	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.729	0.271	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.728	0.272	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.728	0.272	0.000
R40.2 Coma, unspecified	0.727	0.273	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.726	0.274	0.000
E06.3 Autoimmune thyroiditis	0.726	0.274	0.000
G62 Other polyneuropathies	0.723	0.277	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.723	0.277	0.000
A65-A69 Other spirochaetal diseases	0.723	0.277	0.000
R43 Disturbances of smell and taste	0.722	0.278	0.000
M35.0 Sicca syndrome [Sjogren]	0.722	0.278	0.000
D86.1 Sarcoidosis of lymph nodes	0.720	0.280	0.000
E78.4 Other hyperlipidaemia	0.720	0.280	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.719	0.281	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.281	0.719
M07 Psoriatic and enteropathic arthropathies	0.002	0.282	0.716
C91.1 Chronic lymphocytic leukaemia	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E31 Polyglandular dysfunction	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.284	0.000
D50.1 Sideropenic dysphagia	0.716	0.284	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.716	0.284	0.000
N06 Isolated proteinuria with specified morphological lesion	0.716	0.284	0.000
N01 Rapidly progressive nephritic syndrome	0.716	0.284	0.000
N00 Acute nephritic syndrome	0.716	0.284	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.284	0.716
M06.2 Rheumatoid bursitis	0.000	0.284	0.716
M06.1 Adult-onset Still's disease	0.000	0.284	0.716
E27.5 Adrenomedullary hyperfunction	0.716	0.284	0.000
E27.0 Other adrenocortical overactivity	0.716	0.284	0.000
D67 Hereditary factor IX deficiency	0.715	0.284	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.715	0.285	0.000
D69.8 Other specified haemorrhagic conditions	0.715	0.285	0.000
D69.1 Qualitative platelet defects	0.715	0.285	0.000
E14.4 With neurological complications	0.715	0.285	0.000
E03.5 Myxoedema coma	0.715	0.285	0.000
E03.4 Atrophy of thyroid (acquired)	0.715	0.285	0.000
E03.3 Postinfectious hypothyroidism	0.715	0.285	0.000
E03.1 Congenital hypothyroidism without goitre	0.715	0.285	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.715	0.285	0.000
G11.9 Hereditary ataxia, unspecified	0.715	0.285	0.000
D83 Common variable immunodeficiency	0.714	0.285	0.000
M20-M25 Other joint disorders	0.714	0.286	0.000
E06.9 Thyroiditis, unspecified	0.713	0.287	0.000
M35 Other systemic involvement of connective tissue	0.713	0.287	0.000
M60.9 Myositis, unspecified	0.713	0.287	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.713	0.287	0.000
N04.8 Other	0.713	0.287	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.713	0.287	0.000
N04.6 Dense deposit disease	0.713	0.287	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.713	0.287	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.713	0.287	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.713	0.287	0.000
N04.0 Minor glomerular abnormality	0.713	0.287	0.000
E74 Other disorders of carbohydrate metabolism	0.713	0.287	0.000
E26 Hyperaldosteronism	0.712	0.288	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.003	0.288	0.708
M08 Juvenile arthritis	0.003	0.288	0.708
N08.8 Glomerular disorders in other diseases classified elsewhere	0.711	0.289	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.711	0.289	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.711	0.289	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.711	0.289	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.711	0.289	0.000
H49.4 Progressive external ophthalmoplegia	0.711	0.289	0.000
I70 Atherosclerosis	0.711	0.289	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.711	0.289	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.711	0.289	0.000
M05.8 Other seropositive rheumatoid arthritis	0.002	0.289	0.709
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.289	0.709
M05.2 Rheumatoid vasculitis	0.002	0.289	0.709
M05.1 Rheumatoid lung disease	0.002	0.289	0.709
M05.0 Felty's syndrome	0.002	0.289	0.709
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.289	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.710	0.289	0.000
A75-A79 Rickettsioses	0.710	0.289	0.000
A70-A74 Other diseases caused by chlamydiae	0.710	0.289	0.000
A20-A28 Certain zoonotic bacterial diseases	0.710	0.289	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.289	0.710
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.289	0.710
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.289	0.710
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.289	0.710
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.289	0.710
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.289	0.710
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.289	0.710
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.289	0.710
M81.0 Postmenopausal osteoporosis	0.710	0.289	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.290	0.710
C40-C41 Malignant neoplasms of bone and articular cartilage	0.710	0.290	0.000
C81.2 Mixed cellularity	0.709	0.291	0.000
R46.4 Slowness and poor responsiveness	0.709	0.291	0.000
N17.2 Acute renal failure with medullary necrosis	0.708	0.292	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.708	0.292	0.000
B01 Varicella [chickenpox]	0.708	0.292	0.000
E27.8 Other specified disorders of adrenal gland	0.707	0.293	0.000
E20 Hypoparathyroidism	0.707	0.293	0.000
M00 Pyogenic arthritis	0.707	0.293	0.000
R62 Lack of expected normal physiological development	0.705	0.294	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.295	0.705
D73.1 Hypersplenism	0.704	0.296	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.704	0.296	0.000
M62.0 Diastasis of muscle	0.703	0.297	0.000
R54 Senility	0.702	0.298	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.702	0.298	0.000
H50.1 Divergent concomitant strabismus	0.702	0.298	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.702	0.298	0.000
Q44.5 Other congenital malformations of bile ducts	0.702	0.298	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.701	0.299	0.000
N05.6 Dense deposit disease	0.701	0.299	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.701	0.299	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.701	0.299	0.000
N05.0 Minor glomerular abnormality	0.701	0.299	0.000
E14.7 With multiple complications	0.701	0.299	0.000
E14.5 With peripheral circulatory complications	0.701	0.299	0.000
E14.0 With coma	0.701	0.299	0.000
E24.2 Drug-induced Cushing's syndrome	0.700	0.300	0.000
R60.9 Oedema, unspecified	0.700	0.300	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.699	0.301	0.000
B44 Aspergillosis	0.699	0.301	0.000
C86 Other specified types of T/NK-cell lymphoma	0.699	0.301	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.697	0.303	0.000
C94 Other leukaemias of specified cell type	0.697	0.303	0.000
R74.8 Abnormal levels of other serum enzymes	0.697	0.303	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.697	0.303	0.000
A31 Infection due to other mycobacteria	0.697	0.303	0.000
H46 Optic neuritis	0.696	0.304	0.000
L54 Erythema in diseases classified elsewhere	0.696	0.304	0.000
C93 Monocytic leukaemia	0.696	0.304	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations