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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7758976
log Bayes Factor = 67.1818
Chromosome 6   position 30,987,786  (GRCh37) Explore rs7758976 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.005 0.995
E03.9 Hypothyroidism, unspecified
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
L40.0 Psoriasis vulgaris
0.973 0.027 0.000
G35 Multiple sclerosis
0.000 0.045 0.955
E06 Thyroiditis
0.000 0.063 0.937
K90 Intestinal malabsorption
0.000 0.108 0.892
E06.3 Autoimmune thyroiditis
0.000 0.144 0.856
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.159 0.841
E53.8 Deficiency of other specified B group vitamins
0.000 0.192 0.808
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.193 0.807
E53 Deficiency of other B group vitamins
0.000 0.195 0.805
E06.9 Thyroiditis, unspecified
0.000 0.195 0.805
E50-E64 Other nutritional deficiencies
0.000 0.202 0.798
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.205 0.795
L40.1 Generalised pustular psoriasis
0.762 0.238 0.000
E03.8 Other specified hypothyroidism
0.000 0.254 0.746
K90.9 Intestinal malabsorption, unspecified
0.000 0.271 0.729
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.286 0.713
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.713
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.713
E53.9 Vitamin B deficiency, unspecified
0.000 0.287 0.713
K90.8 Other intestinal malabsorption
0.000 0.288 0.712
L40.4 Guttate psoriasis
0.710 0.290 0.000
L40.8 Other psoriasis
0.701 0.299 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.312 0.688
E06.5 Other chronic thyroiditis
0.000 0.326 0.673
E06.4 Drug-induced thyroiditis
0.000 0.328 0.671
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.328 0.671
E06.0 Acute thyroiditis
0.000 0.328 0.671
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.337 0.662
E03.1 Congenital hypothyroidism without goitre
0.000 0.340 0.660
L40.3 Pustulosis palmaris et plantaris
0.658 0.342 0.000
E07 Other disorders of thyroid
0.000 0.360 0.640
K90.3 Pancreatic steatorrhoea
0.000 0.360 0.640
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.360 0.640
K90.1 Tropical sprue
0.000 0.360 0.640
E06.1 Subacute thyroiditis
0.000 0.362 0.638
G37 Other demyelinating diseases of central nervous system
0.000 0.363 0.637
E58 Dietary calcium deficiency
0.000 0.390 0.610
E51 Thiamine deficiency
0.000 0.404 0.596
E04 Other non-toxic goitre
0.000 0.412 0.588
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.420 0.579
E53.1 Pyridoxine deficiency
0.000 0.422 0.577
E53.0 Riboflavin deficiency
0.000 0.422 0.577
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.423 0.577
E56 Other vitamin deficiencies
0.000 0.427 0.573
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.428 0.572
E63 Other nutritional deficiencies
0.000 0.428 0.572
E50 Vitamin A deficiency
0.000 0.428 0.572
E60 Dietary zinc deficiency
0.000 0.428 0.572
E59 Dietary selenium deficiency
0.000 0.428 0.572
E52 Niacin deficiency [pellagra]
0.000 0.428 0.572
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.432 0.568
E05.8 Other thyrotoxicosis
0.000 0.443 0.556
E61 Deficiency of other nutrient elements
0.000 0.449 0.551
E40-E46 Malnutrition
0.000 0.451 0.549
E54 Ascorbic acid deficiency
0.000 0.452 0.548
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.461 0.539
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E04.0 Non-toxic diffuse goitre
0.000 0.493 0.507
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.500 0.500
E04.2 Non-toxic multinodular goitre
0.000 0.518 0.482
G36 Other acute disseminated demyelination
0.000 0.518 0.482
E07.8 Other specified disorders of thyroid
0.000 0.520 0.480
E55 Vitamin D deficiency
0.000 0.528 0.472
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.541 0.459
E07.1 Dyshormogenetic goitre
0.000 0.541 0.459
E07.0 Hypersecretion of calcitonin
0.000 0.541 0.459
G37.5 Concentric sclerosis [Balo]
0.000 0.543 0.456
G37.4 Subacute necrotising myelitis
0.000 0.543 0.456
G37.2 Central pontine myelinolysis
0.000 0.543 0.456
G37.1 Central demyelination of corpus callosum
0.000 0.543 0.456
G37.0 Diffuse sclerosis
0.000 0.543 0.456
E51.2 Wernicke's encephalopathy
0.000 0.549 0.451
E51.9 Thiamine deficiency, unspecified
0.000 0.573 0.427
E51.8 Other manifestations of thiamine deficiency
0.000 0.573 0.427
E51.1 Beriberi
0.000 0.573 0.427
E04.8 Other specified non-toxic goitre
0.000 0.578 0.422
E70-E90 Metabolic disorders
0.000 0.584 0.416
E89.0 Postprocedural hypothyroidism
0.000 0.586 0.414
E56.1 Deficiency of vitamin K
0.000 0.588 0.412
E56.9 Vitamin deficiency, unspecified
0.000 0.589 0.411
E56.8 Deficiency of other vitamins
0.000 0.589 0.411
E56.0 Deficiency of vitamin E
0.000 0.589 0.411
E50.9 Vitamin A deficiency, unspecified
0.000 0.590 0.410
E50.8 Other manifestations of vitamin A deficiency
0.000 0.590 0.410
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.590 0.410
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.590 0.410
E50.5 Vitamin A deficiency with night blindness
0.000 0.590 0.410
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.590 0.410
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.590 0.410
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.590 0.410
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.590 0.410
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.590 0.410
E63.9 Nutritional deficiency, unspecified
0.000 0.590 0.410
E63.8 Other specified nutritional deficiencies
0.000 0.590 0.410
E63.1 Imbalance of constituents of food intake
0.000 0.590 0.410
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.590 0.410
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.590 0.410
E64.8 Sequelae of other nutritional deficiencies
0.000 0.590 0.410
E64.3 Sequelae of rickets
0.000 0.590 0.410
E64.2 Sequelae of vitamin C deficiency
0.000 0.590 0.410
E64.1 Sequelae of vitamin A deficiency
0.000 0.590 0.410
E64.0 Sequelae of protein-energy malnutrition
0.000 0.590 0.410
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.590 0.410
L40-L45 Papulosquamous disorders
0.399 0.601 0.000
E61.1 Iron deficiency
0.000 0.603 0.397
E61.9 Deficiency of nutrient element, unspecified
0.000 0.605 0.395
E61.8 Deficiency of other specified nutrient elements
0.000 0.605 0.395
E61.7 Deficiency of multiple nutrient elements
0.000 0.605 0.395
E61.6 Vanadium deficiency
0.000 0.605 0.395
E61.5 Molybdenum deficiency
0.000 0.605 0.395
E61.4 Chromium deficiency
0.000 0.605 0.395
E61.3 Manganese deficiency
0.000 0.605 0.395
E61.0 Copper deficiency
0.000 0.605 0.395
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.606 0.394
E45 Retarded development following protein-energy malnutrition
0.000 0.606 0.394
E43 Unspecified severe protein-energy malnutrition
0.000 0.606 0.394
E42 Marasmic kwashiorkor
0.000 0.606 0.394
E41 Nutritional marasmus
0.000 0.606 0.394
E40 Kwashiorkor
0.000 0.606 0.394
E83.1 Disorders of iron metabolism
0.000 0.617 0.383
E83 Disorders of mineral metabolism
0.000 0.620 0.380
E46 Unspecified protein-energy malnutrition
0.000 0.627 0.373
E61.2 Magnesium deficiency
0.000 0.627 0.373
E65-E68 Obesity and other hyperalimentation
0.000 0.631 0.369
E10-E14 Diabetes mellitus
0.000 0.633 0.367
E15 Nondiabetic hypoglycaemic coma
0.000 0.641 0.358
E07.9 Disorder of thyroid, unspecified
0.000 0.652 0.348
G36.9 Acute disseminated demyelination, unspecified
0.000 0.654 0.346
G36.8 Other specified acute disseminated demyelination
0.000 0.654 0.346
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.654 0.346
E55.0 Rickets, active
0.000 0.662 0.338
G36.0 Neuromyelitis optica [Devic]
0.000 0.665 0.335
E10 Insulin-dependent diabetes mellitus
0.000 0.671 0.329
E10.9 Without complications
0.000 0.674 0.326
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.675 0.325
E84 Cystic fibrosis
0.000 0.697 0.302
E77 Disorders of glycoprotein metabolism
0.000 0.701 0.299
E76 Disorders of glycosaminoglycan metabolism
0.000 0.701 0.299
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.701 0.299
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.701 0.299
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.703 0.297
L42 Pityriasis rosea
0.297 0.703 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.703 0.297
L44 Other papulosquamous disorders
0.296 0.704 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.706 0.294
E89.1 Postprocedural hypoinsulinaemia
0.000 0.706 0.294
E79 Disorders of purine and pyrimidine metabolism
0.000 0.711 0.288
E16 Other disorders of pancreatic internal secretion
0.000 0.712 0.288
E88 Other metabolic disorders
0.000 0.713 0.287
E10.3 With ophthalmic complications
0.000 0.714 0.286
L41 Parapsoriasis
0.286 0.714 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.286 0.714 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.714 0.286
E04.9 Non-toxic goitre, unspecified
0.000 0.717 0.283
E44.1 Mild protein-energy malnutrition
0.000 0.717 0.283
E44.0 Moderate protein-energy malnutrition
0.000 0.717 0.283
E85 Amyloidosis
0.000 0.719 0.281
E80.4 Gilbert's syndrome
0.000 0.727 0.273
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.728 0.272
E83.8 Other disorders of mineral metabolism
0.000 0.728 0.272
E83.2 Disorders of zinc metabolism
0.000 0.728 0.272
E83.0 Disorders of copper metabolism
0.000 0.728 0.272
E89.4 Postprocedural ovarian failure
0.000 0.728 0.272
E73 Lactose intolerance
0.000 0.729 0.270
E72 Other disorders of amino-acid metabolism
0.000 0.731 0.268
E89.2 Postprocedural hypoparathyroidism
0.000 0.735 0.265
E67 Other hyperalimentation
0.000 0.735 0.264
E68 Sequelae of hyperalimentation
0.000 0.735 0.264
E10.2 With renal complications
0.000 0.737 0.263
E12 Malnutrition-related diabetes mellitus
0.000 0.737 0.263
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.738 0.262
E65 Localised adiposity
0.000 0.740 0.260
E74 Other disorders of carbohydrate metabolism
0.000 0.741 0.259
L43 Lichen planus
0.251 0.749 0.000
E89.5 Postprocedural testicular hypofunction
0.000 0.750 0.250
E80.1 Porphyria cutanea tarda
0.000 0.751 0.249
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.752 0.248
E20-E35 Disorders of other endocrine glands
0.000 0.753 0.247
E89.3 Postprocedural hypopituitarism
0.000 0.758 0.242
E55.9 Vitamin D deficiency, unspecified
0.000 0.762 0.238
E80.6 Other disorders of bilirubin metabolism
0.000 0.766 0.234
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.767 0.233
E80.5 Crigler-Najjar syndrome
0.000 0.767 0.233
E80.3 Defects of catalase and peroxydase
0.000 0.767 0.233
E80.0 Hereditary erythropoietic porphyria
0.000 0.767 0.233
E27.1 Primary adrenocortical insufficiency
0.000 0.768 0.232
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.769 0.231
E27 Other disorders of adrenal gland
0.000 0.770 0.230
E10.5 With peripheral circulatory complications
0.000 0.773 0.227
L44.0 Pityriasis rubra pilaris
0.222 0.778 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.779 0.221
E84.8 Cystic fibrosis with other manifestations
0.000 0.783 0.217
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.783 0.217
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.783 0.217
E85.4 Organ-limited amyloidosis
0.000 0.785 0.215
E71.3 Disorders of fatty-acid metabolism
0.000 0.786 0.214
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.786 0.214
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.786 0.214
E71.0 Maple-syrup-urine disease
0.000 0.786 0.214
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.786 0.214
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.786 0.214
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.786 0.214
E76.2 Other mucopolysaccharidoses
0.000 0.786 0.214
E76.1 Mucopolysaccharidosis, type II
0.000 0.786 0.214
E76.0 Mucopolysaccharidosis, type I
0.000 0.786 0.214
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.786 0.214
E77.8 Other disorders of glycoprotein metabolism
0.000 0.786 0.214
E77.1 Defects in glycoprotein degradation
0.000 0.786 0.214
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.786 0.214
E13 Other specified diabetes mellitus
0.000 0.787 0.213
E88.3 Tumour lysis syndrome
0.000 0.787 0.213
L44.9 Papulosquamous disorder, unspecified
0.212 0.788 0.000
L44.8 Other specified papulosquamous disorders
0.212 0.788 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.212 0.788 0.000
L44.3 Lichen ruber moniliformis
0.212 0.788 0.000
L44.2 Lichen striatus
0.212 0.788 0.000
L44.1 Lichen nitidus
0.212 0.788 0.000
E10.7 With multiple complications
0.000 0.789 0.211
E85.8 Other amyloidosis
0.000 0.792 0.207
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.793 0.207
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.793 0.207
E79.1 Lesch-Nyhan syndrome
0.000 0.793 0.207
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.793 0.207
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.793 0.207
E16.4 Abnormal secretion of gastrin
0.000 0.793 0.207
E16.3 Increased secretion of glucagon
0.000 0.793 0.207
L41.9 Parapsoriasis, unspecified
0.205 0.795 0.000
L41.8 Other parapsoriasis
0.205 0.795 0.000
L41.5 Retiform parapsoriasis
0.205 0.795 0.000
L41.4 Large plaque parapsoriasis
0.205 0.795 0.000
L41.3 Small plaque parapsoriasis
0.205 0.795 0.000
L41.2 Lymphomatoid papulosis
0.205 0.795 0.000
L41.1 Pityriasis lichenoides chronica
0.205 0.795 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.205 0.795 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.795 0.205
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.795 0.205
E70.2 Disorders of tyrosine metabolism
0.000 0.795 0.205
E70.1 Other hyperphenylalaninaemias
0.000 0.795 0.205
E70.0 Classical phenylketonuria
0.000 0.795 0.205
E14 Unspecified diabetes mellitus
0.000 0.796 0.204
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.798 0.202
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.798 0.202
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.798 0.202
E88.9 Metabolic disorder, unspecified
0.000 0.803 0.197
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.803 0.197
E73.8 Other lactose intolerance
0.000 0.806 0.194
E73.1 Secondary lactase deficiency
0.000 0.806 0.194
E73.0 Congenital lactase deficiency
0.000 0.806 0.194
E14.3 With ophthalmic complications
0.000 0.806 0.194
E10.1 With ketoacidosis
0.000 0.807 0.193
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.807 0.193
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.807 0.193
E72.5 Disorders of glycine metabolism
0.000 0.807 0.193
E72.4 Disorders of ornithine metabolism
0.000 0.807 0.193
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.807 0.193
E72.2 Disorders of urea cycle metabolism
0.000 0.807 0.193
E70.3 Albinism
0.000 0.808 0.192
E22 Hyperfunction of pituitary gland
0.000 0.808 0.192
E29 Testicular dysfunction
0.000 0.809 0.191
E67.8 Other specified hyperalimentation
0.000 0.810 0.190
E67.3 Hypervitaminosis D
0.000 0.810 0.190
E67.2 Megavitamin-B6 syndrome
0.000 0.810 0.190
E67.1 Hypercarotenaemia
0.000 0.810 0.190
E67.0 Hypervitaminosis A
0.000 0.810 0.190
E12.9 Without complications
0.000 0.811 0.189
E12.8 With unspecified complications
0.000 0.811 0.189
E12.7 With multiple complications
0.000 0.811 0.189
E12.6 With other specified complications
0.000 0.811 0.189
E12.5 With peripheral circulatory complications
0.000 0.811 0.189
E12.4 With neurological complications
0.000 0.811 0.189
E12.3 With ophthalmic complications
0.000 0.811 0.189
E12.2 With renal complications
0.000 0.811 0.189
E12.1 With ketoacidosis
0.000 0.811 0.189
E12.0 With coma
0.000 0.811 0.189
E75.6 Lipid storage disorder, unspecified
0.000 0.812 0.188
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.812 0.188
E75.3 Sphingolipidosis, unspecified
0.000 0.812 0.188
E75.1 Other gangliosidosis
0.000 0.812 0.188
E75.0 GM2 gangliosidosis
0.000 0.812 0.188
E20 Hypoparathyroidism
0.000 0.812 0.188
E10.8 With unspecified complications
0.000 0.812 0.187
E88.8 Other specified metabolic disorders
0.000 0.814 0.186
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.814 0.186
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.814 0.186
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.814 0.186
E74.2 Disorders of galactose metabolism
0.000 0.814 0.186
E74.1 Disorders of fructose metabolism
0.000 0.814 0.186
E74.0 Glycogen storage disease
0.000 0.814 0.186
E72.0 Disorders of amino-acid transport
0.000 0.815 0.185
E85.3 Secondary systemic amyloidosis
0.000 0.815 0.185
E80.2 Other porphyria
0.000 0.816 0.184
E83.3 Disorders of phosphorus metabolism
0.000 0.817 0.183
E10.6 With other specified complications
0.000 0.818 0.181
E31 Polyglandular dysfunction
0.000 0.819 0.181
L43.8 Other lichen planus
0.180 0.819 0.000
L43.3 Subacute (active) lichen planus
0.180 0.820 0.000
L43.2 Lichenoid drug reaction
0.180 0.820 0.000
L43.1 Bullous lichen planus
0.180 0.820 0.000
L43.0 Hypertrophic lichen planus
0.180 0.820 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.821 0.179
E75.5 Other lipid storage disorders
0.000 0.822 0.178
E85.9 Amyloidosis, unspecified
0.000 0.822 0.178
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.823 0.177
E32 Diseases of thymus
0.000 0.823 0.177
E30 Disorders of puberty, not elsewhere classified
0.000 0.823 0.177
E22.1 Hyperprolactinaemia
0.000 0.827 0.173
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.828 0.172
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.828 0.172
E73.9 Lactose intolerance, unspecified
0.000 0.834 0.166
E75.2 Other sphingolipidosis
0.000 0.835 0.165
E27.5 Adrenomedullary hyperfunction
0.000 0.835 0.165
E27.0 Other adrenocortical overactivity
0.000 0.835 0.165
E10.4 With neurological complications
0.000 0.838 0.162
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.840 0.159
E16.1 Other hypoglycaemia
0.000 0.841 0.159
E26 Hyperaldosteronism
0.000 0.843 0.157
E25 Adrenogenital disorders
0.000 0.843 0.157
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.843 0.157
E20.9 Hypoparathyroidism, unspecified
0.000 0.843 0.156
E10.0 With coma
0.000 0.846 0.154
E13.8 With unspecified complications
0.000 0.847 0.152
E13.7 With multiple complications
0.000 0.847 0.152
E13.6 With other specified complications
0.000 0.847 0.152
E13.5 With peripheral circulatory complications
0.000 0.847 0.152
E13.4 With neurological complications
0.000 0.847 0.152
E13.3 With ophthalmic complications
0.000 0.847 0.152
E13.2 With renal complications
0.000 0.847 0.152
E13.1 With ketoacidosis
0.000 0.847 0.152
E13.0 With coma
0.000 0.847 0.152
E16.2 Hypoglycaemia, unspecified
0.000 0.849 0.151
E29.1 Testicular hypofunction
0.000 0.849 0.151
E14.6 With other specified complications
0.000 0.850 0.150
E27.2 Addisonian crisis
0.000 0.851 0.149
E14.8 With unspecified complications
0.000 0.853 0.147
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.853 0.146
E14.7 With multiple complications
0.000 0.854 0.146
E14.0 With coma
0.000 0.854 0.146
E28 Ovarian dysfunction
0.000 0.855 0.145
E22.0 Acromegaly and pituitary gigantism
0.000 0.855 0.145
L43.9 Lichen planus, unspecified
0.144 0.856 0.000
E14.5 With peripheral circulatory complications
0.000 0.859 0.141
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.862 0.137
E22.8 Other hyperfunction of pituitary gland
0.000 0.862 0.137
E29.9 Testicular dysfunction, unspecified
0.000 0.863 0.137
E29.8 Other testicular dysfunction
0.000 0.863 0.137
E29.0 Testicular hyperfunction
0.000 0.863 0.137
R31 Unspecified haematuria
0.136 0.864 0.000
E20.8 Other hypoparathyroidism
0.000 0.865 0.135
E20.0 Idiopathic hypoparathyroidism
0.000 0.865 0.135
E31.0 Autoimmune polyglandular failure
0.000 0.867 0.133
E34 Other endocrine disorders
0.000 0.869 0.131
E31.9 Polyglandular dysfunction, unspecified
0.000 0.870 0.130
E31.8 Other polyglandular dysfunction
0.000 0.870 0.130
E31.1 Polyglandular hyperfunction
0.000 0.870 0.130
E30.9 Disorder of puberty, unspecified
0.000 0.873 0.127
E30.8 Other disorders of puberty
0.000 0.873 0.127
E30.1 Precocious puberty
0.000 0.873 0.127
E30.0 Delayed puberty
0.000 0.873 0.127
E32.9 Disease of thymus, unspecified
0.000 0.873 0.127
E32.8 Other diseases of thymus
0.000 0.873 0.127
E32.1 Abscess of thymus
0.000 0.873 0.127
E32.0 Persistent hyperplasia of thymus
0.000 0.873 0.127
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.873 0.127
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.873 0.127
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.873 0.127
E14.2 Withrenal complications
0.000 0.876 0.124
E14.1 With ketoacidosis
0.000 0.876 0.123
E27.9 Disorder of adrenal gland, unspecified
0.000 0.880 0.119
E28.3 Primary ovarian failure
0.000 0.880 0.119
E20.1 Pseudohypoparathyroidism
0.000 0.884 0.115
E26.9 Hyperaldosteronism, unspecified
0.000 0.887 0.113
E26.8 Other hyperaldosteronism
0.000 0.887 0.113
E26.1 Secondary hyperaldosteronism
0.000 0.887 0.113
E25.9 Adrenogenital disorder, unspecified
0.000 0.887 0.113
E25.8 Other adrenogenital disorders
0.000 0.887 0.113
E14.4 With neurological complications
0.000 0.891 0.109
E83.5 Disorders of calcium metabolism
0.000 0.894 0.106
E83.4 Disorders of magnesium metabolism
0.000 0.894 0.106
E23 Hypofunction and other disorders of pituitary gland
0.000 0.895 0.105
E28.9 Ovarian dysfunction, unspecified
0.000 0.895 0.104
E28.8 Other ovarian dysfunction
0.000 0.895 0.104
E28.1 Androgen excess
0.000 0.895 0.104
E28.0 Oestrogen excess
0.000 0.895 0.104
E24 Cushing's syndrome
0.001 0.897 0.102
E13.9 Without complications
0.000 0.898 0.102
E34.0 Carcinoid syndrome
0.000 0.903 0.097
E34.5 Androgen resistance syndrome
0.000 0.906 0.094
E34.4 Constitutional tall stature
0.000 0.906 0.094
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.906 0.094
E34.1 Other hypersecretion of intestinal hormones
0.000 0.906 0.094
E34.3 Short stature, not elsewhere classified
0.000 0.906 0.094
E26.0 Primary hyperaldosteronism
0.000 0.907 0.093
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.907 0.093
E27.8 Other specified disorders of adrenal gland
0.000 0.912 0.088
E23.7 Disorder of pituitary gland, unspecified
0.000 0.921 0.079
E86 Volume depletion
0.000 0.923 0.077
E34.8 Other specified endocrine disorders
0.000 0.923 0.077
E66 Obesity
0.000 0.924 0.076
E24.0 Pituitary-dependent Cushing's disease
0.001 0.925 0.075
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.925 0.075
E23.1 Drug-induced hypopituitarism
0.000 0.925 0.075
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.926 0.074
E24.3 Ectopic ACTH syndrome
0.001 0.926 0.074
E24.1 Nelson's syndrome
0.001 0.926 0.074
M35.0 Sicca syndrome [Sjogren]
0.000 0.926 0.074
E34.9 Endocrine disorder, unspecified
0.000 0.929 0.071
E24.8 Other Cushing's syndrome
0.001 0.931 0.068
E24.2 Drug-induced Cushing's syndrome
0.001 0.931 0.068
K90-K93 Other diseases of the digestive system
0.000 0.932 0.068
E23.2 Diabetes insipidus
0.000 0.932 0.067
E04.1 Non-toxic single thyroid nodule
0.000 0.933 0.067
E23.6 Other disorders of pituitary gland
0.000 0.934 0.066
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.938 0.062
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.940 0.060
E66.1 Drug-induced obesity
0.000 0.945 0.054
J47 Bronchiectasis
0.000 0.945 0.055
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.948 0.052
E66.8 Other obesity
0.000 0.949 0.051
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.951 0.049
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.951 0.048
E21.2 Other hyperparathyroidism
0.000 0.953 0.047
F41.9 Anxiety disorder, unspecified
0.047 0.953 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.958 0.042
F41 Other anxiety disorders
0.042 0.958 0.000
M35 Other systemic involvement of connective tissue
0.000 0.958 0.042
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.041 0.959 0.000
F41.2 Mixed anxiety and depressive disorder
0.040 0.960 0.000
E66.0 Obesity due to excess calories
0.000 0.964 0.035
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.964 0.035
K93.1 Megacolon in Chagas' disease
0.000 0.964 0.035
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.964 0.035
M35.7 Hypermobility syndrome
0.000 0.965 0.035
E23.0 Hypopituitarism
0.000 0.966 0.034
M35.1 Other overlap syndromes
0.000 0.968 0.032
E28.2 Polycystic ovarian syndrome
0.001 0.969 0.030
M35.2 Behcet's disease
0.000 0.969 0.030
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.970 0.030
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.970 0.030
M35.5 Multifocal fibrosclerosis
0.000 0.970 0.030
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.970 0.030
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.970 0.030
M35.3 Polymyalgia rheumatica
0.000 0.970 0.030
F41.8 Other specified anxiety disorders
0.029 0.971 0.000
E24.9 Cushing's syndrome, unspecified
0.002 0.971 0.027
M35.8 Other specified systemic involvement of connective tissue
0.000 0.971 0.028
F41.3 Other mixed anxiety disorders
0.024 0.976 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.977 0.023
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.978 0.022
C32.0 Glottis
0.021 0.979 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.980 0.020
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.980 0.020
E87.6 Hypokalaemia
0.000 0.982 0.018
E87.4 Mixed disorder of acid-base balance
0.000 0.983 0.016
D23.1 Skin of eyelid, including canthus
0.000 0.984 0.016
E21.0 Primary hyperparathyroidism
0.000 0.984 0.016
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.984 0.016
E87.5 Hyperkalaemia
0.000 0.985 0.015
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.985 0.015
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.985 0.015
E21.3 Hyperparathyroidism, unspecified
0.000 0.985 0.015
Q61 Cystic kidney disease
0.015 0.985 0.000
Q61.3 Polycystic kidney, unspecified
0.014 0.985 0.000
R30-R39 Symptoms and signs involving the urinary system
0.015 0.985 0.000
Q61.2 Polycystic kidney, adult type
0.014 0.986 0.000
Q61.0 Congenital single renal cyst
0.014 0.986 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.986 0.014
K91.1 Postgastric surgery syndromes
0.000 0.986 0.014
R30 Pain associated with micturition
0.014 0.986 0.000
R30.0 Dysuria
0.013 0.987 0.000
C32 Malignant neoplasm of larynx
0.013 0.987 0.000
R34 Anuria and oliguria
0.012 0.988 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.988 0.012
M62.8 Other specified disorders of muscle
0.000 0.989 0.011
Q61.4 Renal dysplasia
0.011 0.989 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.000 0.989 0.011
Q61.9 Cystic kidney disease, unspecified
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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