TreeWAS – Variant ID: rs77958594

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter XIV Diseases of the genitourinary system	0.999	0.001
K20-K31 Diseases of oesophagus, stomach and duodenum	0.995	0.005
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.993	0.007
M50-M54 Other dorsopathies	0.992	0.008
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.989	0.011
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.989	0.011
N00-N08 Glomerular diseases	0.984	0.016
Chapter IV Endocrine, nutritional and metabolic diseases	0.983	0.017
N17-N19 Renal failure	0.982	0.018
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.980	0.020
M45-M49 Spondylopathies	0.979	0.021
M54 Dorsalgia	0.976	0.024
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.976	0.024
R19 Other symptoms and signs involving the digestive system and abdomen	0.975	0.025
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.975	0.025
K21 Gastro-oesophageal reflux disease	0.971	0.029
N80-N98 Noninflammatory disorders of female genital tract	0.971	0.029
N18 Chronic renal failure	0.969	0.031
K26 Duodenal ulcer	0.968	0.032
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.964	0.036
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.959	0.041
Chapter II Neoplasms	0.958	0.042
K08 Other disorders of teeth and supporting structures	0.956	0.044
R06 Abnormalities of breathing	0.953	0.047
D10-D36 Benign neoplasms	0.949	0.051
R07 Pain in throat and chest	0.945	0.055
K70-K77 Diseases of liver	0.945	0.055
M54.9 Dorsalgia, unspecified	0.940	0.060
I34 Nonrheumatic mitral valve disorders	0.937	0.063
E70-E90 Metabolic disorders	0.935	0.065
L20-L30 Dermatitis and eczema	0.934	0.066
D68 Other coagulation defects	0.930	0.070
I42 Cardiomyopathy	0.929	0.071
K08.3 Retained dental root	0.925	0.075
M20-M25 Other joint disorders	0.925	0.075
I45 Other conduction disorders	0.925	0.075
M54.3 Sciatica	0.924	0.076
D25 Leiomyoma of uterus	0.919	0.081
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.917	0.083
M47 Spondylosis	0.916	0.084
M50 Cervical disk disorders	0.916	0.084
I70-I79 Diseases of arteries, arterioles and capillaries	0.914	0.086
K22 Other diseases of oesophagus	0.910	0.090
D25.9 Leiomyoma of uterus, unspecified	0.908	0.092
L00-L08 Infections of the skin and subcutaneous tissue	0.908	0.092
N02 Recurrent and persistent haematuria	0.906	0.094
I49 Other cardiac arrhythmias	0.905	0.095
E20-E35 Disorders of other endocrine glands	0.903	0.097
M54.99 Dorsalgia, unspecified (Site unspecified)	0.902	0.098
D50-D53 Nutritional anaemias	0.900	0.100
N03 Chronic nephritic syndrome	0.898	0.102
M54.39 Sciatica (Site unspecified)	0.898	0.102
L80-L99 Other disorders of the skin and subcutaneous tissue	0.895	0.105
I47 Paroxysmal tachycardia	0.893	0.107
M70-M79 Other soft tissue disorders	0.891	0.109
N70-N77 Inflammatory diseases of female pelvic organs	0.888	0.112
M47.9 Spondylosis, unspecified	0.887	0.113
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.887	0.113
R05 Cough	0.884	0.116
K65-K67 Diseases of peritoneum	0.883	0.117
I34.0 Mitral (valve) insufficiency	0.883	0.117
R07.2 Precordial pain	0.882	0.118
R15 Faecal incontinence	0.882	0.118
L30 Other dermatitis	0.878	0.122
N18.5 Chronic kidney disease, stage 5	0.876	0.124
I33 Acute and subacute endocarditis	0.876	0.124
K22.1 Ulcer of oesophagus	0.873	0.127
M05-M14 Inflammatory polyarthropathies	0.872	0.128
M80-M85 Disorders of bone density and structure	0.870	0.130
R19.4 Change in bowel habit	0.870	0.130
N86 Erosion and ectropion of cervix uteri	0.867	0.133
R06.0 Dyspnoea	0.865	0.135
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.863	0.137
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.859	0.141
N92 Excessive, frequent and irregular menstruation	0.859	0.141
N99-N99 Other disorders of the genitourinary system	0.857	0.143
N87 Dysplasia of cervix uteri	0.857	0.143
K74 Fibrosis and cirrhosis of liver	0.856	0.144
K26.3 Acute without haemorrhage or perforation	0.856	0.144
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.853	0.147
I60-I69 Cerebrovascular diseases	0.850	0.150
D37-D48 Neoplasms of uncertain or unknown behaviour	0.848	0.152
M50.1 Cervical disk disorder with radiculopathy	0.847	0.153
D68.9 Coagulation defect, unspecified	0.846	0.154
D50 Iron deficiency anaemia	0.845	0.155
N02.9 Unspecified	0.844	0.156
R06.8 Other and unspecified abnormalities of breathing	0.842	0.158
E87 Other disorders of fluid, electrolyte and acid-base balance	0.842	0.158
I42.9 Cardiomyopathy, unspecified	0.839	0.161
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.838	0.162
N03.9 Unspecified	0.837	0.163
M45 Ankylosing spondylitis	0.836	0.164
R07.4 Chest pain, unspecified	0.834	0.166
L03 Cellulitis	0.834	0.166
Chapter V Mental and behavioural disorders	0.833	0.167
N18.2 Chronic kidney disease, stage 2	0.833	0.167
N88 Other noninflammatory disorders of cervix uteri	0.832	0.168
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.832	0.168
N18.0 End-stage renal disease	0.829	0.171
I73 Other peripheral vascular diseases	0.829	0.171
M48 Other spondylopathies	0.827	0.173
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.826	0.174
E83 Disorders of mineral metabolism	0.826	0.174
N19 Unspecified renal failure	0.826	0.174
N92.0 Excessive and frequent menstruation with regular cycle	0.825	0.175
D69 Purpura and other haemorrhagic conditions	0.824	0.176
L40-L45 Papulosquamous disorders	0.824	0.176
L30.9 Dermatitis, unspecified	0.823	0.177
I45.3 Trifascicular block	0.823	0.177
I37 Pulmonary valve disorders	0.819	0.181
I47.1 Supraventricular tachycardia	0.818	0.182
K25 Gastric ulcer	0.817	0.183
K65 Peritonitis	0.814	0.186
K02 Dental caries	0.813	0.187
E00-E07 Disorders of thyroid gland	0.811	0.189
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.809	0.191
R03 Abnormal blood-pressure reading, without diagnosis	0.809	0.191
N08 Glomerular disorders in diseases classified elsewhere	0.808	0.192
N18.4 Chronic kidney disease, stage 4	0.808	0.192
M23 Internal derangement of knee	0.807	0.193
M79 Other soft tissue disorders, not elsewhere classified	0.806	0.194
M86-M90 Other osteopathies	0.802	0.198
N80 Endometriosis	0.802	0.198
K14 Diseases of tongue	0.801	0.199
I44 Atrioventricular and left bundle-branch block	0.801	0.199
M13 Other arthritis	0.800	0.200
D12.8 Rectum	0.798	0.202
L08 Other local infections of skin and subcutaneous tissue	0.798	0.202
F40-F48 Neurotic, stress-related and somatoform disorders	0.797	0.203
D27 Benign neoplasm of ovary	0.797	0.203
I45.9 Conduction disorder, unspecified	0.797	0.203
K75 Other inflammatory liver diseases	0.795	0.205
K72 Hepatic failure, not elsewhere classified	0.792	0.207
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.791	0.209
D12.2 Ascending colon	0.790	0.210
D36 Benign neoplasm of other and unspecified sites	0.789	0.211
K11 Diseases of salivary glands	0.789	0.211
R01 Cardiac murmurs and other cardiac sounds	0.788	0.212
I33.0 Acute and subacute infective endocarditis	0.788	0.212
D68.8 Other specified coagulation defects	0.788	0.212
M35 Other systemic involvement of connective tissue	0.787	0.213
L89 Decubitus ulcer	0.785	0.215
D12.0 Caecum	0.784	0.216
Chapter XXII Codes for special purposes	0.783	0.217
I42.0 Dilated cardiomyopathy	0.780	0.220
R07.1 Chest pain on breathing	0.780	0.220
L29 Pruritus	0.778	0.222
E23 Hypofunction and other disorders of pituitary gland	0.777	0.223
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.777	0.223
L91 Hypertrophic disorders of skin	0.776	0.224
K26.7 Chronic without haemorrhage or perforation	0.775	0.225
K05 Gingivitis and periodontal diseases	0.775	0.225
D50.9 Iron deficiency anaemia, unspecified	0.775	0.225
E40-E46 Malnutrition	0.774	0.225
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.774	0.226
N93 Other abnormal uterine and vaginal bleeding	0.773	0.227
M77 Other enthesopathies	0.773	0.227
K12 Stomatitis and related lesions	0.773	0.227
N70 Salpingitis and oophoritis	0.772	0.228
I35 Nonrheumatic aortic valve disorders	0.772	0.228
K08.2 Atrophy of edentulous alveolar ridge	0.770	0.230
M47.92 Spondylosis, unspecified (Cervical region)	0.769	0.231
R06.5 Mouth breathing	0.768	0.232
I38 Endocarditis, valve unspecified	0.767	0.233
N80.9 Endometriosis, unspecified	0.766	0.234
D69.6 Thrombocytopenia, unspecified	0.765	0.235
M47.96 Spondylosis, unspecified (Lumbar region)	0.764	0.236
I10-I15 Hypertensive diseases	0.763	0.237
R17 Unspecified jaundice	0.762	0.238
L03.0 Cellulitis of finger and toe	0.762	0.238
E87.2 Acidosis	0.761	0.239
M23.3 Other meniscus derangements	0.757	0.243
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.757	0.243
N60-N64 Disorders of breast	0.756	0.244
S20-S29 Injuries to the thorax	0.756	0.244
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.755	0.245
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.755	0.245
K04 Diseases of pulp and periapical tissues	0.754	0.245
K35-K38 Diseases of appendix	0.754	0.246
D18 Haemangioma and lymphangioma, any site	0.754	0.246
N04 Nephrotic syndrome	0.753	0.246
N18.9 Chronic renal failure, unspecified	0.753	0.247
D68.5 Primary Thrombophilia	0.752	0.248
I50 Heart failure	0.751	0.249
D10 Benign neoplasm of mouth and pharynx	0.750	0.250
I64 Stroke, not specified as haemorrhage or infarction	0.749	0.250
M13.9 Arthritis, unspecified	0.748	0.252
D68.2 Hereditary deficiency of other clotting factors	0.748	0.252
M00-M03 Infectious arthropathies	0.748	0.252
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.747	0.253
Chapter VIII Diseases of the ear and mastoid process	0.747	0.253
M47.99 Spondylosis, unspecified (Site unspecified)	0.746	0.254
N18.3 Chronic kidney disease, stage 3	0.744	0.256
M46 Other inflammatory spondylopathies	0.742	0.258
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.742	0.258
M54.5 Low back pain	0.742	0.258
L43 Lichen planus	0.741	0.259
K76 Other diseases of liver	0.741	0.259
K22.0 Achalasia of cardia	0.740	0.259
E87.7 Fluid overload	0.740	0.260
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.739	0.261
N05 Unspecified nephritic syndrome	0.739	0.261
M25 Other joint disorders, not elsewhere classified	0.738	0.262
E10-E14 Diabetes mellitus	0.738	0.262
D25.2 Subserosal leiomyoma of uterus	0.737	0.263
M80 Osteoporosis with pathological fracture	0.737	0.263
I49.8 Other specified cardiac arrhythmias	0.736	0.264
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.736	0.264
I49.4 Other and unspecified premature depolarisation	0.736	0.264
N87.0 Mild cervical dysplasia	0.735	0.265
R06.6 Hiccough	0.735	0.265
D12.4 Descending colon	0.735	0.265
M50.0 Cervical disk disorder with myelopathy	0.734	0.266
N73 Other female pelvic inflammatory diseases	0.734	0.266
D26 Other benign neoplasms of uterus	0.734	0.266
L84 Corns and callosities	0.734	0.266
I77 Other disorders of arteries and arterioles	0.733	0.267
N89 Other noninflammatory disorders of vagina	0.733	0.267
I05-I09 Chronic rheumatic heart diseases	0.732	0.268
C45 Mesothelioma	0.732	0.268
I49.5 Sick sinus syndrome	0.732	0.268
I49.9 Cardiac arrhythmia, unspecified	0.727	0.273
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.727	0.273
L92 Granulomatous disorders of skin and subcutaneous tissue	0.727	0.273
D23 Other benign neoplasms of skin	0.726	0.274
N83.1 Corpus luteum cyst	0.725	0.275
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.724	0.276
K74.6 Other and unspecified cirrhosis of liver	0.723	0.277
F41 Other anxiety disorders	0.721	0.279
E27 Other disorders of adrenal gland	0.720	0.280
K86 Other diseases of pancreas	0.719	0.281
K85 Acute pancreatitis	0.719	0.281
K74.0 Hepatic fibrosis	0.718	0.282
I73.0 Raynaud's syndrome	0.718	0.282
M48.0 Spinal stenosis	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I36 Nonrheumatic tricuspid valve disorders	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I30 Acute pericarditis	0.717	0.283
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.716	0.284
D00-D09 In situ neoplasms	0.716	0.284
N87.1 Moderate cervical dysplasia	0.715	0.285
I34.1 Mitral (valve) prolapse	0.714	0.286
K28 Gastrojejunal ulcer	0.713	0.286
K23 Disorders of oesophagus in diseases classified elsewhere	0.713	0.286
N93.0 Postcoital and contact bleeding	0.713	0.287
M10 Gout	0.713	0.287
K65.0 Acute peritonitis	0.713	0.287
F43 Reaction to severe stress, and adjustment disorders	0.712	0.288
R95-R99 Ill-defined and unknown causes of mortality	0.712	0.288
R03.1 Nonspecific low blood-pressure reading	0.712	0.288
M53 Other dorsopathies, not elsewhere classified	0.711	0.288
K22.9 Disease of oesophagus, unspecified	0.711	0.288
M22 Disorders of patella	0.711	0.289
M13.99 Arthritis, unspecified (Site unspecified)	0.710	0.290
L10-L14 Bullous disorders	0.710	0.290
E05 Thyrotoxicosis [hyperthyroidism]	0.709	0.291
K10 Other diseases of jaws	0.709	0.291
K09 Cysts of oral region, not elsewhere classified	0.709	0.291
K03 Other diseases of hard tissues of teeth	0.709	0.291
K00 Disorders of tooth development and eruption	0.709	0.291
E88 Other metabolic disorders	0.709	0.291
M24 Other specific joint derangements	0.708	0.291
M31 Other necrotising vasculopathies	0.708	0.291
K06 Other disorders of gingiva and edentulous alveolar ridge	0.707	0.293
R10 Abdominal and pelvic pain	0.707	0.293
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.706	0.294
F41.9 Anxiety disorder, unspecified	0.706	0.294
D34 Benign neoplasm of thyroid gland	0.705	0.294
N07 Hereditary nephropathy, not elsewhere classified	0.705	0.294
N06 Isolated proteinuria with specified morphological lesion	0.705	0.294
N01 Rapidly progressive nephritic syndrome	0.705	0.294
N00 Acute nephritic syndrome	0.705	0.294
L03.9 Cellulitis, unspecified	0.705	0.295
D60-D64 Aplastic and other anaemias	0.704	0.296
D55-D59 Haemolytic anaemias	0.702	0.298
M49 Spondylopathies in diseases classified elsewhere	0.702	0.298
Chapter VI Diseases of the nervous system	0.702	0.298
K72.0 Acute and subacute hepatic failure	0.701	0.299
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.701	0.299
I73.9 Peripheral vascular disease, unspecified	0.701	0.299
K65.9 Peritonitis, unspecified	0.700	0.300
E89.3 Postprocedural hypopituitarism	0.700	0.300
M54.8 Other dorsalgia	0.699	0.300
M54.6 Pain in thoracic spine	0.699	0.300
M54.0 Panniculitis affecting regions of neck and back	0.699	0.300
K27 Peptic ulcer, site unspecified	0.699	0.301
E89.0 Postprocedural hypothyroidism	0.699	0.301
R19.6 Halitosis	0.699	0.301
R19.3 Abdominal rigidity	0.699	0.301
R19.2 Visible peristalsis	0.699	0.301
R19.1 Abnormal bowel sounds	0.699	0.301
I70 Atherosclerosis	0.699	0.301
D45 Polycythaemia vera	0.698	0.302
N94.1 Dyspareunia	0.698	0.302
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.697	0.303
N98 Complications associated with artificial fertilisation	0.696	0.304
N91 Absent, scanty and rare menstruation	0.696	0.304
N82 Fistulae involving female genital tract	0.696	0.304
N96 Habitual aborter	0.696	0.304
L30.8 Other specified dermatitis	0.696	0.304
S22 Fracture of rib(s), sternum and thoracic spine	0.695	0.305
N18.8 Other chronic renal failure	0.695	0.305
N18.1 Chronic kidney disease, stage 1	0.695	0.305
L83 Acanthosis nigricans	0.694	0.306
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.694	0.306
K26.5 Chronic or unspecified with perforation	0.694	0.306
K26.2 Acute with both haemorrhage and perforation	0.694	0.306
K26.1 Acute with perforation	0.694	0.306
K26.0 Acute with haemorrhage	0.694	0.306
M54.4 Lumbago with sciatica	0.691	0.309
K01 Embedded and impacted teeth	0.691	0.309
I12 Hypertensive renal disease	0.690	0.310
M81 Osteoporosis without pathological fracture	0.690	0.310
I37.1 Pulmonary valve insufficiency	0.690	0.310
K11.6 Mucocele of salivary gland	0.690	0.310
N70.1 Chronic salpingitis and oophoritis	0.690	0.310
E83.1 Disorders of iron metabolism	0.689	0.311
R18 Ascites	0.688	0.312
K02.9 Dental caries, unspecified	0.688	0.312
D67 Hereditary factor IX deficiency	0.688	0.312
D66 Hereditary factor VIII deficiency	0.688	0.312
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.688	0.312
M45.X9 Ankylosing spondylitis (Site unspecified)	0.688	0.312
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.687	0.312
C40-C41 Malignant neoplasms of bone and articular cartilage	0.687	0.313
K75.9 Inflammatory liver disease, unspecified	0.686	0.314
K08.0 Exfoliation of teeth due to systemic causes	0.685	0.314
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.684	0.316
K22.2 Oesophageal obstruction	0.683	0.316
R06.7 Sneezing	0.683	0.317
R06.3 Periodic breathing	0.683	0.317
R06.1 Stridor	0.683	0.317
N08.3 Glomerular disorders in diabetes mellitus	0.682	0.317
K81 Cholecystitis	0.682	0.318
L43.9 Lichen planus, unspecified	0.682	0.318
N88.8 Other specified noninflammatory disorders of cervix uteri	0.681	0.319
D31 Benign neoplasm of eye and adnexa	0.681	0.319
D30 Benign neoplasm of urinary organs	0.681	0.319
D29 Benign neoplasm of male genital organs	0.681	0.319
D28 Benign neoplasm of other and unspecified female genital organs	0.681	0.319
D21 Other benign neoplasms of connective and other soft tissue	0.681	0.319
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.681	0.319
D19 Benign neoplasm of mesothelial tissue	0.681	0.319
D16 Benign neoplasm of bone and articular cartilage	0.681	0.319
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.681	0.319
D14 Benign neoplasm of middle ear and respiratory system	0.681	0.319
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.680	0.319
N62 Hypertrophy of breast	0.679	0.321
I67 Other cerebrovascular diseases	0.679	0.321
M35.3 Polymyalgia rheumatica	0.679	0.321
K08.8 Other specified disorders of teeth and supporting structures	0.679	0.321
N02.8 Other	0.678	0.322
D23.6 Skin of upper limb, including shoulder	0.678	0.322
K77 Liver disorders in diseases classified elsewhere	0.678	0.322
K73 Chronic hepatitis, not elsewhere classified	0.678	0.322
K71 Toxic liver disease	0.678	0.322
L89.1 Stage II decubitus ulcer	0.678	0.322
M79.8 Other specified soft tissue disorders	0.677	0.323
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.677	0.323
I78 Diseases of capillaries	0.676	0.324
D46 Myelodysplastic syndromes	0.675	0.325
N76 Other inflammation of vagina and vulva	0.675	0.325
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.674	0.326
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.674	0.326
M54.94 Dorsalgia, unspecified (Thoracic region)	0.674	0.326
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.674	0.326
M54.92 Dorsalgia, unspecified (Cervical region)	0.674	0.326
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.674	0.326
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.674	0.326
D36.1 Peripheral nerves and autonomic nervous system	0.674	0.326
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.674	0.326
I35.0 Aortic (valve) stenosis	0.672	0.327
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.671	0.328
I34.8 Other nonrheumatic mitral valve disorders	0.671	0.328
I34.2 Nonrheumatic mitral (valve) stenosis	0.671	0.328
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.671	0.329
E85 Amyloidosis	0.671	0.329
E84 Cystic fibrosis	0.671	0.329
E79 Disorders of purine and pyrimidine metabolism	0.671	0.329
E77 Disorders of glycoprotein metabolism	0.671	0.329
E76 Disorders of glycosaminoglycan metabolism	0.671	0.329
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.671	0.329
E74 Other disorders of carbohydrate metabolism	0.671	0.329
E73 Lactose intolerance	0.671	0.329
E72 Other disorders of amino-acid metabolism	0.671	0.329
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.671	0.329
E70 Disorders of aromatic amino-acid metabolism	0.671	0.329
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.671	0.329
I45.6 Preexcitation syndrome	0.670	0.330
Q20-Q28 Congenital malformations of the circulatory system	0.670	0.330
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.670	0.330
L25 Unspecified contact dermatitis	0.669	0.331
L24 Irritant contact dermatitis	0.669	0.331
L23 Allergic contact dermatitis	0.669	0.331
L21 Seborrhoeic dermatitis	0.669	0.331
L20 Atopic dermatitis	0.669	0.331
L26 Exfoliative dermatitis	0.669	0.331
L22 Diaper [napkin] dermatitis	0.669	0.331
Chapter I Certain infectious and parasitic diseases	0.669	0.331
K04.6 Periapical abscess with sinus	0.668	0.332
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.668	0.332
L91.8 Other hypertrophic disorders of skin	0.667	0.333
D68.6 Other Thrombophilia	0.667	0.333
D68.4 Acquired coagulation factor deficiency	0.667	0.333
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.667	0.333
D68.1 Hereditary factor XI deficiency	0.667	0.333
D68.0 Von Willebrand's disease	0.667	0.333
K83 Other diseases of biliary tract	0.666	0.334
D50.8 Other iron deficiency anaemias	0.666	0.334
I42.8 Other cardiomyopathies	0.666	0.334
I42.7 Cardiomyopathy due to drugs and other external agents	0.666	0.334
I42.6 Alcoholic cardiomyopathy	0.666	0.334
I42.5 Other restrictive cardiomyopathy	0.666	0.334
I42.4 Endocardial fibroelastosis	0.666	0.334
I42.3 Endomyocardial (eosinophilic) disease	0.666	0.334
I42.2 Other hypertrophic cardiomyopathy	0.666	0.334
I42.1 Obstructive hypertrophic cardiomyopathy	0.666	0.334
K25.7 Chronic without haemorrhage or perforation	0.666	0.334
L28 Lichen simplex chronicus and prurigo	0.665	0.335
D52 Folate deficiency anaemia	0.665	0.335
K08.9 Disorder of teeth and supporting structures, unspecified	0.664	0.336
I60 Subarachnoid haemorrhage	0.664	0.336
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.663	0.336
M34 Systemic sclerosis	0.663	0.336
M33 Dermatopolymyositis	0.663	0.336
M32 Systemic lupus erythematosus	0.663	0.336
M30 Polyarteritis nodosa and related conditions	0.663	0.336
N25-N29 Other disorders of kidney and ureter	0.663	0.337
I45.8 Other specified conduction disorders	0.663	0.337
I45.5 Other specified heart block	0.663	0.337
I45.4 Nonspecific intraventricular block	0.663	0.337
I45.2 Bifascicular block	0.663	0.337
I45.0 Right fascicular block	0.663	0.337
N90 Other noninflammatory disorders of vulva and perineum	0.663	0.337
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.662	0.337
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.662	0.338
M54.37 Sciatica (Lumbosacral region)	0.662	0.338
M54.35 Sciatica (Thoracolumbar region)	0.662	0.338
M54.34 Sciatica-Thoracic	0.662	0.338
M54.33 Sciatica-Cervicothoracic	0.662	0.338
M54.32 Sciatica-Cervical	0.662	0.338
M54.31 Sciatica-Occipit-atl-axl	0.662	0.338
M54.30 Sciatica (Multiple sites in spine)	0.662	0.338
D11 Benign neoplasm of major salivary glands	0.662	0.338
M51 Other intervertebral disk disorders	0.661	0.339
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.660	0.340
M21 Other acquired deformities of limbs	0.659	0.341
M71 Other bursopathies	0.658	0.341
S80-S89 Injuries to the knee and lower leg	0.659	0.341
N92.1 Excessive and frequent menstruation with irregular cycle	0.657	0.343
M65-M68 Disorders of synovium and tendon	0.657	0.343
L03.8 Cellulitis of other sites	0.657	0.343
M47.1 Other spondylosis with myelopathy	0.657	0.343
M47.0 Anterior spinal and vertebral artery compression syndromes	0.657	0.343
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.657	0.343
M50.9 Cervical disk disorder, unspecified	0.656	0.343
M50.8 Other cervical disk disorders	0.656	0.343
M89 Other disorders of bone	0.656	0.343
M54.56 Low back pain (Lumbar region)	0.656	0.344
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.656	0.344
D25.1 Intramural leiomyoma of uterus	0.656	0.344
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.655	0.344
I72 Other aneurysm	0.655	0.344
I49.0 Ventricular fibrillation and flutter	0.655	0.345
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.654	0.346
I80 Phlebitis and thrombophlebitis	0.654	0.346
E28 Ovarian dysfunction	0.653	0.347
I87 Other disorders of veins	0.653	0.347
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.653	0.347
M77.0 Medial epicondylitis	0.653	0.347
N71 Inflammatory disease of uterus, except cervix	0.653	0.347
I81 Portal vein thrombosis	0.653	0.347
K07 Dentofacial anomalies [including malocclusion]	0.653	0.347
I44.2 Atrioventricular block, complete	0.652	0.348
K22.5 Diverticulum of oesophagus, acquired	0.652	0.348
K22.3 Perforation of oesophagus	0.652	0.348
K74.3 Primary biliary cirrhosis	0.652	0.348
R10.1 Pain localised to upper abdomen	0.652	0.348
L04 Acute lymphadenitis	0.651	0.349
L01 Impetigo	0.651	0.349
L00 Staphylococcal scalded skin syndrome	0.651	0.349
I44.3 Other and unspecified atrioventricular block	0.651	0.349
K25.4 Chronic or unspecified with haemorrhage	0.651	0.349

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations