TreeWAS – Variant ID: rs7799006

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C22.1 Intrahepatic bile duct carcinoma	0.235	0.765	0.000
C22.0 Liver cell carcinoma	0.232	0.768	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.231	0.769	0.000
C22.9 Liver, unspecified	0.210	0.790	0.000
C22.7 Other specified carcinomas of liver	0.166	0.834	0.000
C22.4 Other sarcomas of liver	0.166	0.834	0.000
C22.3 Angiosarcoma of liver	0.166	0.834	0.000
C22.2 Hepatoblastoma	0.166	0.834	0.000
E04.1 Non-toxic single thyroid nodule	0.023	0.977	0.000
N42.8 Other specified disorders of prostate	0.000	0.977	0.023
E04.9 Non-toxic goitre, unspecified	0.020	0.980	0.000
E04 Other non-toxic goitre	0.019	0.981	0.000
E04.0 Non-toxic diffuse goitre	0.017	0.983	0.000
K81.9 Cholecystitis, unspecified	0.017	0.983	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.986	0.014
E04.8 Other specified non-toxic goitre	0.014	0.986	0.000
T93 Sequelae of injuries of lower limb	0.000	0.988	0.012
T93.0 Sequelae of open wound of lower limb	0.000	0.988	0.012
T93.1 Sequelae of fracture of femur	0.000	0.988	0.012
N42 Other disorders of prostate	0.000	0.989	0.011
G45.9 Transient cerebral ischaemic attack, unspecified	0.011	0.989	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.990	0.010
N42.9 Disorder of prostate, unspecified	0.000	0.990	0.010
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.991	0.009
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.991	0.009
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.991	0.009
N42.0 Calculus of prostate	0.000	0.991	0.009
N42.1 Congestion and haemorrhage of prostate	0.000	0.992	0.008
N42.3 Dysplasia of prostate	0.000	0.992	0.008
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.992	0.008
N42.2 Atrophy of prostate	0.000	0.993	0.007
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.993	0.006
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.994	0.006
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.994	0.006
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.006	0.994	0.000
T90 Sequelae of injuries of head	0.000	0.994	0.006
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.994	0.006
Z82.3 Family history of stroke	0.006	0.994	0.000
T92 Sequelae of injuries of upper limb	0.000	0.994	0.006
U80.0 Penicillin resistant agent	0.000	0.994	0.006
I25.3 Aneurysm of heart	0.006	0.994	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.994	0.006
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
T90.8 Sequelae of other specified injuries of head	0.000	0.995	0.005
Y52 Agents primarily affecting the cardiovascular system	0.005	0.995	0.000
S51.8 Open wound of other parts of forearm	0.000	0.995	0.005
H52.0 Hypermetropia	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
T90.1 Sequelae of open wound of head	0.000	0.995	0.005
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.000	0.995	0.005
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.005	0.995	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.995	0.005
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.995	0.005
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.995	0.005
Y42.7 Androgens and anabolic congeners	0.005	0.995	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.995	0.005
F31 Bipolar affective disorder	0.000	0.995	0.005
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.995	0.005
U80 Agent resistant to penicillin and related antibiotics	0.000	0.995	0.005
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
T90.4 Sequelae of injury of eye and orbit	0.000	0.996	0.004
T94 Sequelae of injuries involving multiple and unspecified body regions	0.000	0.996	0.004
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.996	0.004
S51.0 Open wound of elbow	0.000	0.996	0.004
Y42.2 Antithyroid drugs	0.004	0.996	0.000
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
T90.3 Sequelae of injury of cranial nerves	0.000	0.996	0.004
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
T95 Sequelae of burns, corrosions and frostbite	0.000	0.996	0.004
T91 Sequelae of injuries of neck and trunk	0.000	0.996	0.004
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
T98 Sequelae of other and unspecified effects of external causes	0.000	0.996	0.004
T90.5 Sequelae of intracranial injury	0.000	0.996	0.004
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.996	0.004
K81 Cholecystitis	0.004	0.996	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.004
T90.0 Sequelae of superficial injury of head	0.000	0.996	0.004
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.996	0.004
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
S51 Open wound of forearm	0.000	0.996	0.004
Y42.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
C34.0 Main bronchus	0.004	0.996	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.996	0.004
G59.0 Diabetic mononeuropathy	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.996	0.004
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.996	0.004
U80.1 Methicillin resistant agent	0.000	0.996	0.004
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.996	0.004
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.996	0.004
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.004	0.996	0.000
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
Z82.1 Family history of blindness and visual loss	0.004	0.996	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.004
H52 Disorders of refraction and accommodation	0.004	0.996	0.000
K37 Unspecified appendicitis	0.000	0.996	0.004
Y42.4 Oral contraceptives	0.003	0.996	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.996	0.000
Z82.2 Family history of deafness and hearing loss	0.003	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.004	0.996	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.996	0.004
T91.1 Sequelae of fracture of spine	0.000	0.996	0.004
K04.7 Periapical abscess without sinus	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
H52.3 Anisometropia and aniseikonia	0.003	0.997	0.000
O12.0 Gestational oedema	0.003	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.000	0.997	0.003
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.000	0.997	0.003
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.000	0.997	0.003
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.000	0.997	0.003
H52.2 Astigmatism	0.003	0.997	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.997	0.003
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.997	0.003
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.997	0.003
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.000	0.997	0.003
T98.2 Sequelae of certain early complications of trauma	0.000	0.997	0.003
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.997	0.003
H50.2 Vertical strabismus	0.003	0.997	0.000
L73.8 Other specified follicular disorders	0.003	0.997	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
Z73.3 Stress, not elsewhere classified	0.003	0.997	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.997	0.003
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.000	0.997	0.003
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
H50 Other strabismus	0.003	0.997	0.000
T94.1 Sequelae of injuries, not specified by body region	0.000	0.997	0.003
V18.0 Driver injured in nontraffic accident	0.000	0.997	0.003
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
L03.1 Cellulitis of other parts of limb	0.000	0.997	0.003
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
K81.1 Chronic cholecystitis	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
H50.6 Mechanical strabismus	0.003	0.997	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.000	0.997	0.003
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
K81.8 Other cholecystitis	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
H50.9 Strabismus, unspecified	0.003	0.997	0.000
S51.7 Multiple open wounds of forearm	0.000	0.997	0.003
H52.6 Other disorders of refraction	0.003	0.997	0.000
H52.5 Disorders of accommodation	0.003	0.997	0.000
N90.5 Atrophy of vulva	0.000	0.997	0.003
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.997	0.003
Y59.3 Immunoglobulin	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
K66.0 Peritoneal adhesions	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
G45.3 Amaurosis fugax	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.003	0.997	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.000	0.997	0.003
H52.7 Disorder of refraction, unspecified	0.003	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
T92.0 Sequelae of open wound of upper limb	0.000	0.997	0.002
H52.4 Presbyopia	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.997	0.003
H50.4 Other and unspecified heterotropia	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
H49 Paralytic strabismus	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.997	0.003
K66.1 Haemoperitoneum	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.002	0.997	0.000
H51 Other disorders of binocular movement	0.002	0.997	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
Y59.0 Viral vaccines	0.002	0.997	0.000
H50.3 Intermittent heterotropia	0.002	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.997	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
K66 Other disorders of peritoneum	0.002	0.998	0.000
N17.0 Acute renal failure with tubular necrosis	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
K66.9 Disorder of peritoneum, unspecified	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
F20 Schizophrenia	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.002	0.998	0.000
H51.2 Internuclear ophthalmoplegia	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.002	0.998	0.000
H50.8 Other specified strabismus	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.002	0.998	0.000
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
N28.8 Other specified disorders of kidney and ureter	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
G45.0 Vertebro-basilar artery syndrome	0.002	0.998	0.000
H51.9 Disorder of binocular movement, unspecified	0.002	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.002	0.998	0.000
H51.1 Convergence insufficiency and excess	0.002	0.998	0.000
H51.0 Palsy of conjugate gaze	0.002	0.998	0.000
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.000	0.998	0.002
H50.5 Heterophoria	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
J85.2 Abscess of lung without pneumonia	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
Z35.4 Supervision of pregnancy with grand multiparity	0.002	0.998	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.998	0.002
M41.8 Other forms of scoliosis	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
F20.8 Other schizophrenia	0.000	0.998	0.002
O12.1 Gestational proteinuria	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
D16.4 Bones of skull and face	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
U50 Level of care administered to neonates	0.000	0.998	0.002
U07 Emergency use of U07	0.000	0.998	0.002
U06 Emergency use of U06	0.000	0.998	0.002
U04 Severe acute respiratory syndrome [SARS]	0.000	0.998	0.002
U52 First in a series of a regular day/night admissions	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.998	0.002
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.002
H49.9 Paralytic strabismus, unspecified	0.001	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
V18.3 Person injured while boarding or alighting	0.000	0.998	0.002
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.998	0.002
C78.7 Secondary malignant neoplasm of liver	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y53.4 Other laxatives	0.001	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.998	0.002
I49.9 Cardiac arrhythmia, unspecified	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.002
K25.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.001
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
T17.3 Foreign body in larynx	0.002	0.998	0.000
V18.1 Passenger injured in nontraffic accident	0.000	0.998	0.002
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.998	0.002
I77.6 Arteritis, unspecified	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
V18.5 Passenger injured in traffic accident	0.000	0.998	0.001
Y54.7 Agents affecting calcification	0.001	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.000	0.998	0.002
T01.2 Open wounds involving multiple regions of upper limb(s)	0.000	0.998	0.001
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.998	0.001
U06.9 Emergency use of U06.9	0.000	0.998	0.001
U06.8 Emergency use of U06.8	0.000	0.998	0.001
U06.7 Emergency use of U06.7	0.000	0.998	0.001
U06.6 Emergency use of U06.6	0.000	0.998	0.001
U06.5 Emergency use of U06.5	0.000	0.998	0.001
U06.4 Emergency use of U06.4	0.000	0.998	0.001
U06.3 Emergency use of U06.3	0.000	0.998	0.001
U06.2 Emergency use of U06.2	0.000	0.998	0.001
U06.1 Emergency use of U06.1	0.000	0.998	0.001
U06.0 Emergency use of U06.0	0.000	0.998	0.001
U07.9 Emergency use of U07.9	0.000	0.998	0.001
U07.8 Emergency use of U07.8	0.000	0.998	0.001
U07.7 Emergency use of U07.7	0.000	0.998	0.001
U07.6 Emergency use of U07.6	0.000	0.998	0.001
U07.5 Emergency use of U07.5	0.000	0.998	0.001
U07.4 Emergency use of U07.4	0.000	0.998	0.001
U07.3 Emergency use of U07.3	0.000	0.998	0.001
U07.2 Emergency use of U07.2	0.000	0.998	0.001
U07.1 Emergency use of U07.1	0.000	0.998	0.001
U07.0 Emergency use of U07.0	0.000	0.998	0.001
U50.9 Inquest Adjourned Death	0.000	0.998	0.001
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.000	0.998	0.001
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.000	0.998	0.001
U50.1 Level of care administered to neonates (Special Care)	0.000	0.998	0.001
U50.0 Level of care administered to neonates (Normal Care)	0.000	0.998	0.001
Y57.5 X-ray contrast media	0.001	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
D16.3 Short bones of lower limb	0.000	0.998	0.001
G59.8 Other mononeuropathies in diseases classified elsewhere	0.001	0.998	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.998	0.001
V18.4 Driver injured in traffic accident	0.000	0.998	0.001
Y45.8 Other analgesics and antipyretics	0.001	0.998	0.000
L73 Other follicular disorders	0.002	0.998	0.000
U51 Admission status on psychiatric patients	0.000	0.998	0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.001	0.998	0.000
M41.4 Neuromuscular scoliosis	0.001	0.998	0.000
M41.3 Thoracogenic scoliosis	0.001	0.998	0.000
M41.2 Other idiopathic scoliosis	0.001	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.001	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.001	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.000	0.998	0.001
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.001
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
Y51.0 Anticholinesterase agents	0.001	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.999	0.000
Z73.6 Limitation of activities due to disability	0.001	0.999	0.000
M06.34 Rheumatoid nodule (Hand)	0.001	0.999	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.001	0.999	0.000
M06.3 Rheumatoid nodule	0.001	0.999	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
C26.9 Ill-defined sites within the digestive system	0.001	0.999	0.000
F32.0 Mild depressive episode	0.000	0.999	0.001
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.999	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.999	0.001
O21.0 Mild hyperemesis gravidarum	0.001	0.999	0.000
C10.9 Oropharynx, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations