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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78049802
log Bayes Factor = 10.8707
Chromosome 4   position 24,302,114  (GRCh37) Explore rs78049802 on Ensembl!
Variant rs78049802 is part of Cluster X0074

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.998 0.002 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.996 0.004 0.000
F17.1 Harmful use
0.995 0.005 0.000
R47-R49 Symptoms and signs involving speech and voice
0.994 0.006 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.984 0.016 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.980 0.020 0.000
A30-A49 Other bacterial diseases
0.980 0.020 0.000
Chapter VIII Diseases of the ear and mastoid process
0.975 0.025 0.000
R47 Speech disturbances, not elsewhere classified
0.975 0.025 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.972 0.028 0.000
R06 Abnormalities of breathing
0.971 0.029 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.964 0.036 0.000
H65-H75 Diseases of middle ear and mastoid
0.964 0.036 0.000
R06.5 Mouth breathing
0.963 0.037 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.957 0.043 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.945 0.055 0.000
R49 Voice disturbances
0.932 0.068 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.932 0.068 0.000
E00-E07 Disorders of thyroid gland
0.932 0.068 0.000
F10.0 Acute intoxication
0.931 0.069 0.000
A49 Bacterial infection of unspecified site
0.926 0.074 0.000
D80-D89 Certain disorders involving the immune mechanism
0.917 0.083 0.000
R21 Rash and other nonspecific skin eruption
0.915 0.085 0.000
R06.0 Dyspnoea
0.910 0.090 0.000
R20 Disturbances of skin sensation
0.908 0.092 0.000
H66 Suppurative and unspecified otitis media
0.905 0.095 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.904 0.096 0.000
Chapter X Diseases of the respiratory system
0.903 0.097 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.899 0.101 0.000
H74 Other disorders of middle ear and mastoid
0.898 0.102 0.000
J30-J39 Other diseases of upper respiratory tract
0.897 0.103 0.000
A46 Erysipelas
0.892 0.108 0.000
S80-S89 Injuries to the knee and lower leg
0.891 0.109 0.000
B95-B98 Bacterial, viral and other infectious agents
0.889 0.111 0.000
E20-E35 Disorders of other endocrine glands
0.889 0.111 0.000
R49.0 Dysphonia
0.888 0.112 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.888 0.112 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.888 0.112 0.000
J34 Other disorders of nose and nasal sinuses
0.887 0.113 0.000
R47.8 Other and unspecified speech disturbances
0.885 0.115 0.000
F80-F89 Disorders of psychological development
0.883 0.117 0.000
R20.2 Paraesthesia of skin
0.883 0.117 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.880 0.120 0.000
R47.0 Dysphasia and aphasia
0.877 0.123 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.871 0.129 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.870 0.130 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.865 0.135 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.864 0.136 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.856 0.144 0.000
E50-E64 Other nutritional deficiencies
0.856 0.144 0.000
R47.1 Dysarthria and anarthria
0.855 0.145 0.000
R29.6 Tendency to fall, not elsewhere classified
0.852 0.148 0.000
H66.3 Other chronic suppurative otitis media
0.852 0.148 0.000
E05.9 Thyrotoxicosis, unspecified
0.852 0.148 0.000
R26 Abnormalities of gait and mobility
0.846 0.154 0.000
R27 Other lack of coordination
0.845 0.155 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.845 0.155 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.844 0.156 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.843 0.157 0.000
D86 Sarcoidosis
0.841 0.159 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.841 0.159 0.000
T92 Sequelae of injuries of upper limb
0.840 0.160 0.000
S10-S19 Injuries to the neck
0.837 0.163 0.000
J31.0 Chronic rhinitis
0.837 0.163 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.828 0.172 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.828 0.172 0.000
S80 Superficial injury of lower leg
0.827 0.173 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.822 0.178 0.000
J34.3 Hypertrophy of nasal turbinates
0.822 0.178 0.000
B25-B34 Other viral diseases
0.817 0.183 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.817 0.183 0.000
B15-B19 Viral hepatitis
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.811 0.189 0.000
A49.9 Bacterial infection, unspecified
0.808 0.192 0.000
T91 Sequelae of injuries of neck and trunk
0.804 0.196 0.000
Chapter IX Diseases of the circulatory system
0.803 0.197 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.803 0.197 0.000
E10-E14 Diabetes mellitus
0.803 0.197 0.000
R06.8 Other and unspecified abnormalities of breathing
0.795 0.205 0.000
F10.5 Psychotic disorder
0.795 0.205 0.000
T93 Sequelae of injuries of lower limb
0.790 0.210 0.000
R06.2 Wheezing
0.789 0.211 0.000
L40-L45 Papulosquamous disorders
0.789 0.211 0.000
D68 Other coagulation defects
0.788 0.212 0.000
S80.9 Superficial injury of lower leg, unspecified
0.786 0.214 0.000
F10.2 Dependence syndrome
0.786 0.214 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.785 0.215 0.000
S30.1 Contusion of abdominal wall
0.784 0.216 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.783 0.217 0.000
D80 Immunodeficiency with predominantly antibody defects
0.782 0.218 0.000
H71 Cholesteatoma of middle ear
0.781 0.219 0.000
A49.1 Streptococcal infection, unspecified
0.781 0.219 0.000
A40 Streptococcal septicaemia
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.778 0.222 0.000
A63.0 Anogenital (venereal) warts
0.777 0.223 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.777 0.223 0.000
W20-W49 Exposure to inanimate mechanical forces
0.776 0.224 0.000
F10.6 Amnesic syndrome
0.773 0.227 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.773 0.227 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.772 0.228 0.000
D60-D64 Aplastic and other anaemias
0.771 0.229 0.000
S60-S69 Injuries to the wrist and hand
0.771 0.229 0.000
F80 Specific developmental disorders of speech and language
0.771 0.229 0.000
J34.2 Deviated nasal septum
0.768 0.232 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.768 0.232 0.000
Y45.0 Opioids and related analgesics
0.767 0.233 0.000
A00-A09 Intestinal infectious diseases
0.764 0.236 0.000
E06 Thyroiditis
0.761 0.238 0.000
I74 Arterial embolism and thrombosis
0.761 0.239 0.000
W75-W84 Other accidental threats to breathing
0.761 0.239 0.000
L08 Other local infections of skin and subcutaneous tissue
0.760 0.240 0.000
I60-I69 Cerebrovascular diseases
0.759 0.241 0.000
W00-W19 Falls
0.759 0.241 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.757 0.243 0.000
H90-H95 Other disorders of ear
0.757 0.243 0.000
J39 Other diseases of upper respiratory tract
0.757 0.243 0.000
E53 Deficiency of other B group vitamins
0.756 0.244 0.000
A15-A19 Tuberculosis
0.756 0.244 0.000
T00-T07 Injuries involving multiple body regions
0.755 0.245 0.000
H69 Other disorders of Eustachian tube
0.753 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.752 0.248 0.000
D50-D53 Nutritional anaemias
0.751 0.249 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.749 0.251 0.000
S31 Open wound of abdomen, lower back and pelvis
0.748 0.252 0.000
X20-X29 Contact with venomous animals and plants
0.748 0.252 0.000
I67 Other cerebrovascular diseases
0.747 0.253 0.000
Y40 Systemic antibiotics
0.745 0.255 0.000
A49.0 Staphylococcal infection, unspecified
0.744 0.256 0.000
L50-L54 Urticaria and erythema
0.742 0.258 0.000
D86.0 Sarcoidosis of lung
0.742 0.258 0.000
Y00-Y09 Assault
0.740 0.260 0.000
J09-J18 Influenza and pneumonia
0.738 0.262 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.738 0.262 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.737 0.263 0.000
R27.0 Ataxia, unspecified
0.737 0.263 0.000
J60-J70 Lung diseases due to external agents
0.736 0.264 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.736 0.264 0.000
R40 Somnolence, stupor and coma
0.736 0.264 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.735 0.265 0.000
S32 Fracture of lumbar spine and pelvis
0.734 0.266 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.734 0.266 0.000
S30.2 Contusion of external genital organs
0.733 0.267 0.000
E21.0 Primary hyperparathyroidism
0.733 0.267 0.000
E70-E90 Metabolic disorders
0.733 0.267 0.000
R23 Other skin changes
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.732 0.268 0.000
H70 Mastoiditis and related conditions
0.730 0.270 0.000
X10-X19 Contact with heat and hot substances
0.730 0.270 0.000
J33 Nasal polyp
0.730 0.270 0.000
E23 Hypofunction and other disorders of pituitary gland
0.729 0.271 0.000
F30-F39 Mood [affective] disorders
0.728 0.272 0.000
Y43 Primarily systemic agents
0.727 0.273 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.727 0.273 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.726 0.274 0.000
Chapter VI Diseases of the nervous system
0.726 0.274 0.000
X50-X57 Overexertion, travel and privation
0.726 0.274 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.724 0.276 0.000
V40-V49 Car occupant injured in transport accident
0.724 0.276 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.723 0.276 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.721 0.279 0.000
H73 Other disorders of tympanic membrane
0.720 0.280 0.000
T63 Toxic effect of contact with venomous animals
0.719 0.281 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
Y48 Anaesthetics and therapeutic gases
0.716 0.284 0.000
F17.9 Unspecified mental and behavioural disorder
0.714 0.286 0.000
F17.8 Other mental and behavioural disorders
0.714 0.286 0.000
F17.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F17.6 Amnesic syndrome
0.714 0.286 0.000
F17.5 Psychotic disorder
0.714 0.286 0.000
F17.4 Withdrawal state with delirium
0.714 0.286 0.000
F17.3 Withdrawal state
0.714 0.286 0.000
F17.0 Acute intoxication
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.713 0.286 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.713 0.287 0.000
R29.4 Clicking hip
0.711 0.289 0.000
R29.3 Abnormal posture
0.711 0.289 0.000
R29.2 Abnormal reflex
0.711 0.289 0.000
R29.1 Meningismus
0.711 0.289 0.000
R29.0 Tetany
0.711 0.289 0.000
H74.4 Polyp of middle ear
0.711 0.289 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.710 0.290 0.000
D64 Other anaemias
0.709 0.291 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.709 0.291 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.708 0.291 0.000
F84 Pervasive developmental disorders
0.705 0.295 0.000
R25 Abnormal involuntary movements
0.705 0.295 0.000
A49.8 Other bacterial infections of unspecified site
0.705 0.295 0.000
H66.9 Otitis media, unspecified
0.703 0.297 0.000
N17-N19 Renal failure
0.703 0.297 0.000
A48 Other bacterial diseases, not elsewhere classified
0.703 0.297 0.000
A44 Bartonellosis
0.703 0.297 0.000
A43 Nocardiosis
0.703 0.297 0.000
A42 Actinomycosis
0.703 0.297 0.000
A39 Meningococcal infection
0.703 0.297 0.000
A37 Whooping cough
0.703 0.297 0.000
A36 Diphtheria
0.703 0.297 0.000
A32 Listeriosis
0.703 0.297 0.000
A31 Infection due to other mycobacteria
0.703 0.297 0.000
A30 Leprosy [Hansen's disease]
0.703 0.297 0.000
A38 Scarlet fever
0.703 0.297 0.000
A35 Other tetanus
0.703 0.297 0.000
A34 Obstetrical tetanus
0.703 0.297 0.000
A33 Tetanus neonatorum
0.703 0.297 0.000
T98 Sequelae of other and unspecified effects of external causes
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
N18 Chronic renal failure
0.701 0.299 0.000
J33.9 Nasal polyp, unspecified
0.701 0.299 0.000
F60-F69 Disorders of adult personality and behaviour
0.700 0.300 0.000
A04 Other bacterial intestinal infections
0.699 0.301 0.000
Y52 Agents primarily affecting the cardiovascular system
0.699 0.301 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
N17 Acute renal failure
0.698 0.302 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.698 0.302 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.698 0.302 0.000
R06.7 Sneezing
0.696 0.304 0.000
R06.3 Periodic breathing
0.696 0.304 0.000
I26 Pulmonary embolism
0.696 0.304 0.000
H90 Conductive and sensorineural hearing loss
0.696 0.304 0.000
T51 Toxic effect of alcohol
0.696 0.304 0.000
N17.9 Acute renal failure, unspecified
0.695 0.305 0.000
D68.9 Coagulation defect, unspecified
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
E34 Other endocrine disorders
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.307 0.000
I73 Other peripheral vascular diseases
0.692 0.308 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.692 0.308 0.000
F10.9 Unspecified mental and behavioural disorder
0.691 0.309 0.000
F10.8 Other mental and behavioural disorders
0.691 0.309 0.000
F10.7 Residual and late-onset psychotic disorder
0.691 0.309 0.000
F80.1 Expressive language disorder
0.691 0.309 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.691 0.309 0.000
H68 Eustachian salpingitis and obstruction
0.691 0.309 0.000
H67 Otitis media in diseases classified elsewhere
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
E03 Other hypothyroidism
0.690 0.310 0.000
B65-B83 Helminthiases
0.690 0.310 0.000
S90-S99 Injuries to the ankle and foot
0.689 0.311 0.000
Y44 Agents primarily affecting blood constituents
0.688 0.312 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.688 0.312 0.000
I67.8 Other specified cerebrovascular diseases
0.687 0.313 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.686 0.314 0.000
S37 Injury of urinary and pelvic organs
0.686 0.314 0.000
S36 Injury of intra-abdominal organs
0.686 0.314 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.686 0.314 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.686 0.314 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.686 0.314 0.000
D69 Purpura and other haemorrhagic conditions
0.686 0.314 0.000
E14 Unspecified diabetes mellitus
0.686 0.314 0.000
E53.8 Deficiency of other specified B group vitamins
0.685 0.315 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.685 0.315 0.000
A41 Other septicaemia
0.684 0.316 0.000
S50-S59 Injuries to the elbow and forearm
0.684 0.316 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.684 0.316 0.000
E16 Other disorders of pancreatic internal secretion
0.683 0.317 0.000
L43 Lichen planus
0.683 0.317 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.682 0.318 0.000
T17 Foreign body in respiratory tract
0.680 0.320 0.000
T18 Foreign body in alimentary tract
0.680 0.320 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
J35 Chronic diseases of tonsils and adenoids
0.679 0.321 0.000
F33 Recurrent depressive disorder
0.678 0.322 0.000
X60-X84 Intentional self-harm
0.677 0.322 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
I77 Other disorders of arteries and arterioles
0.677 0.323 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.323 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.676 0.324 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.675 0.325 0.000
R06.1 Stridor
0.675 0.325 0.000
S40-S49 Injuries to the shoulder and upper arm
0.675 0.325 0.000
L53 Other erythematous conditions
0.674 0.326 0.000
E40-E46 Malnutrition
0.674 0.326 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.673 0.327 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.673 0.327 0.000
S86 Injury of muscle and tendon at lower leg level
0.672 0.328 0.000
S81 Open wound of lower leg
0.672 0.328 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.672 0.328 0.000
D86.1 Sarcoidosis of lymph nodes
0.671 0.329 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.670 0.330 0.000
D55-D59 Haemolytic anaemias
0.669 0.331 0.000
J95-J99 Other diseases of the respiratory system
0.669 0.331 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.669 0.331 0.000
R49.8 Other and unspecified voice disturbances
0.668 0.332 0.000
R49.2 Hypernasality and hyponasality
0.668 0.332 0.000
R49.1 Aphonia
0.668 0.332 0.000
Y59 Other and unspecified vaccines and biological substances
0.668 0.332 0.000
Y58 Bacterial vaccines
0.668 0.332 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.332 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.668 0.332 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.668 0.332 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.668 0.332 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.668 0.332 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.668 0.332 0.000
E00 Congenital iodine-deficiency syndrome
0.668 0.332 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.668 0.332 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.668 0.332 0.000
R06.4 Hyperventilation
0.667 0.333 0.000
L40 Psoriasis
0.667 0.333 0.000
B35-B49 Mycoses
0.665 0.335 0.000
D64.9 Anaemia, unspecified
0.665 0.335 0.000
Chapter XIV Diseases of the genitourinary system
0.665 0.335 0.000
T56 Toxic effect of metals
0.664 0.336 0.000
A49.3 Mycoplasma infection, unspecified
0.664 0.336 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.664 0.336 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.663 0.337 0.000
R40.0 Somnolence
0.663 0.337 0.000
A04.8 Other specified bacterial intestinal infections
0.662 0.338 0.000
I67.9 Cerebrovascular disease, unspecified
0.662 0.338 0.000
N18.9 Chronic renal failure, unspecified
0.661 0.339 0.000
R02 Gangrene, not elsewhere classified
0.661 0.339 0.000
R45 Symptoms and signs involving emotional state
0.661 0.339 0.000
N18.3 Chronic kidney disease, stage 3
0.660 0.340 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.659 0.341 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.658 0.342 0.000
I74.5 Embolism and thrombosis of iliac artery
0.658 0.342 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.658 0.342 0.000
D84 Other immunodeficiencies
0.657 0.343 0.000
D83 Common variable immunodeficiency
0.657 0.343 0.000
D82 Immunodeficiency associated with other major defects
0.657 0.343 0.000
D81 Combined immunodeficiencies
0.657 0.343 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.656 0.343 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.656 0.344 0.000
H74.0 Tympanosclerosis
0.654 0.346 0.000
B25 Cytomegaloviral disease
0.654 0.346 0.000
R26.3 Immobility
0.653 0.347 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.653 0.347 0.000
Y45.1 Salicylates
0.652 0.348 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.652 0.348 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.651 0.349 0.000
W29 Contact with other powered hand tools and household machinery
0.651 0.349 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.651 0.349 0.000
R20.3 Hyperaesthesia
0.651 0.349 0.000
R20.1 Hypoaesthesia of skin
0.651 0.349 0.000
R20.0 Anaesthesia of skin
0.651 0.349 0.000
R26.0 Ataxic gait
0.651 0.349 0.000
W17 Other fall from one level to another
0.650 0.350 0.000
J31.2 Chronic pharyngitis
0.649 0.351 0.000
H66.4 Suppurative otitis media, unspecified
0.649 0.351 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.649 0.351 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.649 0.351 0.000
H66.0 Acute suppurative otitis media
0.649 0.351 0.000
T45.0 Antiallergic and antiemetic drugs
0.647 0.353 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.647 0.353 0.000
I70 Atherosclerosis
0.646 0.354 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.646 0.354 0.000
E26 Hyperaldosteronism
0.646 0.354 0.000
S70-S79 Injuries to the hip and thigh
0.645 0.355 0.000
H65 Nonsuppurative otitis media
0.645 0.355 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.645 0.355 0.000
A59 Trichomoniasis
0.645 0.355 0.000
A56 Other sexually transmitted chlamydial diseases
0.645 0.355 0.000
A54 Gonococcal infection
0.645 0.355 0.000
A53 Other and unspecified syphilis
0.645 0.355 0.000
A52 Late syphilis
0.645 0.355 0.000
A51 Early syphilis
0.645 0.355 0.000
A50 Congenital syphilis
0.645 0.355 0.000
A64 Unspecified sexually transmitted disease
0.645 0.355 0.000
A58 Granuloma inguinale
0.645 0.355 0.000
A57 Chancroid
0.645 0.355 0.000
A55 Chlamydial lymphogranuloma (venereum)
0.645 0.355 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.643 0.356 0.000
H74.1 Adhesive middle ear disease
0.643 0.356 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.643 0.356 0.000
I67.2 Cerebral atherosclerosis
0.643 0.357 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.643 0.357 0.000
E61 Deficiency of other nutrient elements
0.643 0.357 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.642 0.358 0.000
D68.5 Primary Thrombophilia
0.642 0.358 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.642 0.358 0.000
Y45.8 Other analgesics and antipyretics
0.641 0.359 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.641 0.359 0.000
E21.3 Hyperparathyroidism, unspecified
0.641 0.359 0.000
T66-T78 Other and unspecified effects of external causes
0.640 0.360 0.000
S12 Fracture of neck
0.639 0.360 0.000
E28 Ovarian dysfunction
0.639 0.361 0.000
T36 Poisoning by systemic antibiotics
0.639 0.361 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.639 0.361 0.000
S88 Traumatic amputation of lower leg
0.639 0.361 0.000
S87 Crushing injury of lower leg
0.639 0.361 0.000
S85 Injury of blood vessels at lower leg level
0.639 0.361 0.000
S84 Injury of nerves at lower leg level
0.639 0.361 0.000
I27 Other pulmonary heart diseases
0.638 0.362 0.000
I73.9 Peripheral vascular disease, unspecified
0.638 0.362 0.000
R06.6 Hiccough
0.637 0.362 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.637 0.362 0.000
E32 Diseases of thymus
0.637 0.362 0.000
E31 Polyglandular dysfunction
0.637 0.362 0.000
E30 Disorders of puberty, not elsewhere classified
0.637 0.362 0.000
E25 Adrenogenital disorders
0.637 0.362 0.000
E24 Cushing's syndrome
0.637 0.362 0.000
E20 Hypoparathyroidism
0.637 0.362 0.000
B15 Acute hepatitis A
0.637 0.363 0.000
E05.8 Other thyrotoxicosis
0.637 0.363 0.000
E05.5 Thyroid crisis or storm
0.637 0.363 0.000
E05.4 Thyrotoxicosis factitia
0.637 0.363 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.637 0.363 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.637 0.363 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.637 0.363 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.636 0.363 0.000
S30.0 Contusion of lower back and pelvis
0.636 0.363 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.636 0.364 0.000
E14.9 Without complications
0.635 0.365 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.635 0.365 0.000
D86.9 Sarcoidosis, unspecified
0.635 0.365 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.634 0.366 0.000
B34 Viral infection of unspecified site
0.634 0.366 0.000
D86.8 Sarcoidosis of other and combined sites
0.633 0.366 0.000
F89 Unspecified disorder of psychological development
0.633 0.367 0.000
F88 Other disorders of psychological development
0.633 0.367 0.000
F83 Mixed specific developmental disorders
0.633 0.367 0.000
F82 Specific developmental disorder of motor function
0.633 0.367 0.000
S89 Other and unspecified injuries of lower leg
0.632 0.368 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.631 0.369 0.000
D67 Hereditary factor IX deficiency
0.631 0.369 0.000
D66 Hereditary factor VIII deficiency
0.631 0.369 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.631 0.369 0.000
H90.5 Sensorineural hearing loss, unspecified
0.631 0.369 0.000
Q80-Q89 Other congenital malformations
0.630 0.369 0.000
I69 Sequelae of cerebrovascular disease
0.630 0.369 0.000
B18 Chronic viral hepatitis
0.630 0.370 0.000
H60-H62 Diseases of external ear
0.630 0.370 0.000
T23 Burn and corrosion of wrist and hand
0.627 0.372 0.000
V10-V19 Pedal cyclist injured in transport accident
0.627 0.373 0.000
I77.1 Stricture of artery
0.627 0.373 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.625 0.374 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.625 0.375 0.000
E11 Non-insulin-dependent diabetes mellitus
0.625 0.375 0.000
T65 Toxic effect of other and unspecified substances
0.624 0.375 0.000
T62 Toxic effect of other noxious substances eaten as food
0.624 0.375 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.624 0.375 0.000
T60 Toxic effect of pesticides
0.624 0.375 0.000
T57 Toxic effect of other inorganic substances
0.624 0.375 0.000
T54 Toxic effect of corrosive substances
0.624 0.375 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.624 0.375 0.000
T52 Toxic effect of organic solvents
0.624 0.375 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.624 0.375 0.000
T58 Toxic effect of carbon monoxide
0.624 0.375 0.000
T55 Toxic effect of soaps and detergents
0.624 0.375 0.000
J39.8 Other specified diseases of upper respiratory tract
0.624 0.376 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.624 0.376 0.000
F99-F99 Unspecified mental disorder
0.623 0.376 0.000
W00 Fall on same level involving ice and snow
0.624 0.376 0.000
L10-L14 Bullous disorders
0.623 0.376 0.000
S64 Injury of nerves at wrist and hand level
0.623 0.377 0.000
H72 Perforation of tympanic membrane
0.623 0.377 0.000
T91.3 Sequelae of injury of spinal cord
0.622 0.378 0.000
F10.3 Withdrawal state
0.622 0.378 0.000
S20-S29 Injuries to the thorax
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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