TreeWAS – Variant ID: rs790006

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K74.6 Other and unspecified cirrhosis of liver	0.040	0.960	0.000
K65.0 Acute peritonitis	0.000	0.962	0.038
K65 Peritonitis	0.000	0.965	0.035
K65.8 Other peritonitis	0.000	0.965	0.035
K74 Fibrosis and cirrhosis of liver	0.031	0.969	0.000
K65.9 Peritonitis, unspecified	0.000	0.971	0.029
K74.5 Biliary cirrhosis, unspecified	0.027	0.973	0.000
K74.3 Primary biliary cirrhosis	0.026	0.974	0.000
K74.0 Hepatic fibrosis	0.024	0.976	0.000
E27 Other disorders of adrenal gland	0.024	0.976	0.000
K74.4 Secondary biliary cirrhosis	0.022	0.977	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.022	0.977	0.000
K74.1 Hepatic sclerosis	0.022	0.978	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.022	0.978	0.000
E20-E35 Disorders of other endocrine glands	0.022	0.978	0.000
E23 Hypofunction and other disorders of pituitary gland	0.021	0.979	0.000
E27.2 Addisonian crisis	0.021	0.979	0.000
I87 Other disorders of veins	0.020	0.980	0.000
I87.1 Compression of vein	0.020	0.980	0.000
E23.0 Hypopituitarism	0.020	0.980	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.020	0.980	0.000
E27.1 Primary adrenocortical insufficiency	0.020	0.980	0.000
E29 Testicular dysfunction	0.020	0.980	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.020	0.980	0.000
E22 Hyperfunction of pituitary gland	0.019	0.981	0.000
I87.8 Other specified disorders of veins	0.019	0.981	0.000
E23.2 Diabetes insipidus	0.019	0.981	0.000
E29.1 Testicular hypofunction	0.018	0.981	0.000
E27.8 Other specified disorders of adrenal gland	0.018	0.982	0.000
E24 Cushing's syndrome	0.018	0.982	0.000
E27.9 Disorder of adrenal gland, unspecified	0.017	0.982	0.000
E26 Hyperaldosteronism	0.017	0.982	0.000
E27.5 Adrenomedullary hyperfunction	0.017	0.983	0.000
E27.0 Other adrenocortical overactivity	0.017	0.983	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.017	0.983	0.000
E22.0 Acromegaly and pituitary gigantism	0.017	0.983	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.983	0.017
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.016	0.983	0.000
E23.7 Disorder of pituitary gland, unspecified	0.016	0.984	0.000
I87.9 Disorder of vein, unspecified	0.016	0.984	0.000
I87.0 Postphlebitic syndrome	0.016	0.984	0.000
E32 Diseases of thymus	0.016	0.984	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.016	0.984	0.000
E30 Disorders of puberty, not elsewhere classified	0.016	0.984	0.000
E23.1 Drug-induced hypopituitarism	0.016	0.984	0.000
E23.6 Other disorders of pituitary gland	0.015	0.984	0.000
E29.9 Testicular dysfunction, unspecified	0.015	0.985	0.000
E26.0 Primary hyperaldosteronism	0.015	0.985	0.000
E29.8 Other testicular dysfunction	0.014	0.985	0.000
E29.0 Testicular hyperfunction	0.014	0.985	0.000
E31 Polyglandular dysfunction	0.014	0.986	0.000
L03.0 Cellulitis of finger and toe	0.014	0.986	0.000
E24.9 Cushing's syndrome, unspecified	0.014	0.986	0.000
E24.0 Pituitary-dependent Cushing's disease	0.014	0.986	0.000
S70 Superficial injury of hip and thigh	0.014	0.986	0.000
E20 Hypoparathyroidism	0.014	0.986	0.000
E22.8 Other hyperfunction of pituitary gland	0.014	0.986	0.000
E25 Adrenogenital disorders	0.014	0.986	0.000
S70.0 Contusion of hip	0.014	0.986	0.000
E34 Other endocrine disorders	0.013	0.986	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.013	0.987	0.000
E24.8 Other Cushing's syndrome	0.013	0.987	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.013	0.987	0.000
E24.3 Ectopic ACTH syndrome	0.013	0.987	0.000
E24.1 Nelson's syndrome	0.013	0.987	0.000
E26.8 Other hyperaldosteronism	0.013	0.987	0.000
E26.1 Secondary hyperaldosteronism	0.013	0.987	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.013	0.987	0.000
E24.2 Drug-induced Cushing's syndrome	0.012	0.987	0.000
E26.9 Hyperaldosteronism, unspecified	0.012	0.988	0.000
E22.1 Hyperprolactinaemia	0.012	0.988	0.000
E32.9 Disease of thymus, unspecified	0.012	0.988	0.000
E32.8 Other diseases of thymus	0.012	0.988	0.000
S70-S79 Injuries to the hip and thigh	0.012	0.988	0.000
E32.1 Abscess of thymus	0.012	0.988	0.000
E32.0 Persistent hyperplasia of thymus	0.012	0.988	0.000
E28 Ovarian dysfunction	0.012	0.988	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.012	0.988	0.000
E30.9 Disorder of puberty, unspecified	0.011	0.988	0.000
E30.8 Other disorders of puberty	0.011	0.988	0.000
E30.1 Precocious puberty	0.011	0.988	0.000
E30.0 Delayed puberty	0.011	0.988	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.011	0.988	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.011	0.988	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.011	0.988	0.000
S70.1 Contusion of thigh	0.011	0.988	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.011	0.989	0.000
E20.1 Pseudohypoparathyroidism	0.011	0.989	0.000
E34.9 Endocrine disorder, unspecified	0.011	0.989	0.000
S73.0 Dislocation of hip	0.011	0.989	0.000
S72 Fracture of femur	0.011	0.989	0.000
S70.8 Other superficial injuries of hip and thigh	0.011	0.989	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.011	0.989	0.000
E31.9 Polyglandular dysfunction, unspecified	0.010	0.989	0.000
E31.8 Other polyglandular dysfunction	0.010	0.989	0.000
E31.1 Polyglandular hyperfunction	0.010	0.989	0.000
E20.8 Other hypoparathyroidism	0.010	0.989	0.000
E20.0 Idiopathic hypoparathyroidism	0.010	0.990	0.000
E25.9 Adrenogenital disorder, unspecified	0.010	0.990	0.000
E25.8 Other adrenogenital disorders	0.010	0.990	0.000
E34.5 Androgen resistance syndrome	0.010	0.990	0.000
E34.4 Constitutional tall stature	0.010	0.990	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.010	0.990	0.000
E34.1 Other hypersecretion of intestinal hormones	0.010	0.990	0.000
E21.4 Other specified disorders of parathyroid gland	0.010	0.990	0.000
E34.8 Other specified endocrine disorders	0.010	0.990	0.000
S71 Open wound of hip and thigh	0.010	0.990	0.000
S72.4 Fracture of lower end of femur	0.010	0.990	0.000
E34.3 Short stature, not elsewhere classified	0.009	0.991	0.000
F32.9 Depressive episode, unspecified	0.000	0.991	0.009
S72.1 Pertrochanteric fracture	0.009	0.991	0.000
E31.0 Autoimmune polyglandular failure	0.009	0.991	0.000
E21.2 Other hyperparathyroidism	0.009	0.991	0.000
S73.1 Sprain and strain of hip	0.009	0.991	0.000
H26.4 After-cataract	0.000	0.991	0.009
S75 Injury of blood vessels at hip and thigh level	0.009	0.991	0.000
S72.2 Subtrochanteric fracture	0.009	0.991	0.000
S74 Injury of nerves at hip and thigh level	0.009	0.991	0.000
S72.9 Fracture of femur, part unspecified	0.009	0.991	0.000
S78 Traumatic amputation of hip and thigh	0.009	0.991	0.000
S77 Crushing injury of hip and thigh	0.009	0.991	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.009	0.991	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.991	0.000
E28.9 Ovarian dysfunction, unspecified	0.008	0.991	0.000
E28.8 Other ovarian dysfunction	0.008	0.991	0.000
E28.1 Androgen excess	0.008	0.991	0.000
E28.0 Oestrogen excess	0.008	0.991	0.000
E28.3 Primary ovarian failure	0.008	0.991	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.008	0.991	0.000
S72.7 Multiple fractures of femur	0.008	0.992	0.000
S71.1 Open wound of thigh	0.008	0.992	0.000
K65-K67 Diseases of peritoneum	0.000	0.992	0.008
S72.10 Pertrochanteric fracture (closed)	0.008	0.992	0.000
S72.41 Fracture of lower end of femur (open)	0.008	0.992	0.000
S72.3 Fracture of shaft of femur	0.008	0.992	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.007	0.992	0.000
S72.40 Fracture of lower end of femur (closed)	0.008	0.992	0.000
S72.8 Fractures of other parts of femur	0.007	0.992	0.000
S72.20 Subtrochanteric fracture (closed)	0.007	0.993	0.000
S71.7 Multiple open wounds of of hip and thigh	0.007	0.993	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.007	0.993	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.007	0.993	0.000
S79 Other and unspecified injuries of hip and thigh	0.007	0.993	0.000
O04.9 Complete or unspecified, without complication	0.000	0.993	0.007
S72.11 Pertrochanteric fracture (open)	0.007	0.993	0.000
S75.0 Injury of femoral artery	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.006	0.993	0.001
E34.0 Carcinoid syndrome	0.006	0.993	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.006	0.993	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.006	0.993	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.006	0.993	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.006	0.993	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.006	0.993	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.006	0.993	0.000
S72.21 Subtrochanteric fracture (open)	0.006	0.993	0.000
S72.70 Multiple fractures of femur (closed)	0.006	0.993	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.006	0.993	0.000
S74.8 Injury of other nerves at hip and thigh level	0.006	0.993	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.006	0.993	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.006	0.993	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.006	0.993	0.000
S72.91 Fracture of femur, part unspecified (open)	0.006	0.993	0.000
S77.2 Crushing injury of hip with thigh	0.006	0.993	0.000
S77.1 Crushing injury of thigh	0.006	0.993	0.000
S77.0 Crushing injury of hip	0.006	0.993	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.006	0.993	0.000
S78.1 Traumatic amputation at level between hip and knee	0.006	0.993	0.000
S78.0 Traumatic amputation at hip joint	0.006	0.993	0.000
S71.0 Open wound of hip	0.006	0.994	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.006	0.994	0.000
S72.71 Multiple fractures of femur (open)	0.006	0.994	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.994	0.006
S72.0 Fracture of neck of femur	0.006	0.994	0.000
S76.0 Injury of muscle and tendon of hip	0.006	0.994	0.000
C83.3 Large cell (diffuse)	0.000	0.994	0.006
S72.31 Fracture of shaft of femur (open)	0.006	0.994	0.000
S76.1 Injury of quadriceps muscle and tendon	0.005	0.994	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.005	0.994	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.005	0.994	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
S72.30 Fracture of shaft of femur (closed)	0.006	0.994	0.000
S72.81 Fractures of other parts of femur (open)	0.005	0.994	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.994	0.006
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.006	0.994	0.000
E21.0 Primary hyperparathyroidism	0.005	0.994	0.000
O04 Medical abortion	0.000	0.995	0.005
S79.7 Multiple injuries of hip and thigh	0.005	0.995	0.000
R68.8 Other specified general symptoms and signs	0.005	0.995	0.000
S72.80 Fractures of other parts of femur (closed)	0.005	0.995	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
K70-K77 Diseases of liver	0.005	0.995	0.000
H43.1 Vitreous haemorrhage	0.000	0.995	0.005
S79.8 Other specified injuries of hip and thigh	0.005	0.995	0.000
E28.2 Polycystic ovarian syndrome	0.005	0.995	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.995	0.005
I08 Multiple valve diseases	0.005	0.995	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.995	0.005
K67.3 Tuberculous peritonitis	0.000	0.995	0.005
K67.2 Syphilitic peritonitis	0.000	0.995	0.005
K67.1 Gonococcal peritonitis	0.000	0.995	0.005
K67.0 Chlamydial peritonitis	0.000	0.995	0.005
E21.3 Hyperparathyroidism, unspecified	0.005	0.995	0.000
K71 Toxic liver disease	0.005	0.995	0.000
S72.01 Fracture of neck of femur (open)	0.004	0.995	0.000
O04.4 Incomplete, without complication	0.000	0.995	0.005
S91 Open wound of ankle and foot	0.000	0.995	0.005
S91.0 Open wound of ankle	0.000	0.995	0.004
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.004	0.995	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.996	0.004
S90-S99 Injuries to the ankle and foot	0.000	0.996	0.004
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.996	0.004
S79.9 Unspecified injury of hip and thigh	0.004	0.996	0.000
S90 Superficial injury of ankle and foot	0.000	0.996	0.004
H43 Disorders of vitreous body	0.000	0.996	0.004
O04.7 Complete or unspecified, complicated by embolism	0.000	0.996	0.004
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.996	0.004
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.996	0.004
O04.3 Incomplete, with other and unspecified complications	0.000	0.996	0.004
O04.2 Incomplete, complicated by embolism	0.000	0.996	0.004
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.996	0.004
K77 Liver disorders in diseases classified elsewhere	0.004	0.996	0.000
C67.5 Bladder neck	0.000	0.996	0.004
I08.8 Other multiple valve diseases	0.004	0.996	0.000
L91.8 Other hypertrophic disorders of skin	0.004	0.996	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.004	0.996	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.996	0.004
S91.1 Open wound of toe(s) without damage to nail	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.000	0.996	0.004
I08.0 Disorders of both mitral and aortic valves	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.996	0.004
K76 Other diseases of liver	0.004	0.996	0.000
C67.0 Trigone of bladder	0.000	0.996	0.004
H43.8 Other disorders of vitreous body	0.000	0.996	0.004
I08.1 Disorders of both mitral and tricuspid valves	0.004	0.996	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.003	0.996	0.001
K71.9 Toxic liver disease, unspecified	0.004	0.996	0.000
S97 Crushing injury of ankle and foot	0.000	0.996	0.004
K71.0 Toxic liver disease with cholestasis	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.996	0.004
C65 Malignant neoplasm of renal pelvis	0.000	0.996	0.004
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.996	0.004
S92.4 Fracture of great toe	0.000	0.996	0.004
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.996	0.004
I08.9 Multiple valve disease, unspecified	0.004	0.996	0.000
S92.5 Fracture of other toe	0.000	0.996	0.004
Z73.3 Stress, not elsewhere classified	0.000	0.996	0.004
K76.8 Other specified diseases of liver	0.004	0.996	0.000
S92.40 Fracture of great toe (closed)	0.000	0.996	0.004
S92.51 Fracture of other toe (open)	0.000	0.996	0.004
H43.3 Other vitreous opacities	0.000	0.996	0.004
K71.8 Toxic liver disease with other disorders of liver	0.003	0.996	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.003	0.996	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.003	0.996	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.003	0.996	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.003	0.996	0.000
K71.2 Toxic liver disease with acute hepatitis	0.003	0.996	0.000
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
O34.2 Maternal care due to uterine scar from previous surgery	0.004	0.996	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.996	0.003
S98 Traumatic amputation of ankle and foot	0.000	0.996	0.003
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.003	0.997	0.000
K76.6 Portal hypertension	0.003	0.997	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.997	0.003
H43.0 Vitreous prolapse	0.000	0.997	0.003
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.997	0.003
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
S90.0 Contusion of ankle	0.000	0.997	0.003
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
K72 Hepatic failure, not elsewhere classified	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.000	0.997	0.003
S97.1 Crushing injury of toe(s)	0.000	0.997	0.003
S92.1 Fracture of talus	0.000	0.997	0.003
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.997	0.003
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
H43.9 Disorder of vitreous body, unspecified	0.000	0.997	0.003
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.997	0.003
S90.2 Contusion of toe(s) with damage to nail	0.000	0.997	0.003
R68 Other general symptoms and signs	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
S93.1 Dislocation of toe(s)	0.000	0.997	0.003
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.997	0.003
K77.8 Liver disorders in other diseases classified elsewhere	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.003
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
K76.1 Chronic passive congestion of liver	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.000	0.997	0.003
K76.5 Hepatic veno-occlusive disease	0.003	0.997	0.000
K76.4 Peliosis hepatis	0.003	0.997	0.000
K76.2 Central haemorrhagic necrosis of liver	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.000	0.997	0.003
S90.1 Contusion of toe(s) without damage to nail	0.000	0.997	0.003
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.997	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.997	0.003
S97.0 Crushing injury of ankle	0.000	0.997	0.003
H43.2 Crystalline deposits in vitreous body	0.000	0.997	0.003
S90.3 Contusion of other and unspecified parts of foot	0.000	0.997	0.003
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.003	0.997	0.000
S93.4 Sprain and strain of ankle	0.000	0.997	0.003
S93.5 Sprain and strain of toe(s)	0.000	0.997	0.003
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.997	0.003
S98.1 Traumatic amputation of one toe	0.000	0.997	0.003
K76.3 Infarction of liver	0.003	0.997	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.003	0.997	0.000
K73 Chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.997	0.003
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
K66 Other disorders of peritoneum	0.000	0.997	0.003
S92.50 Fracture of other toe (closed)	0.000	0.997	0.003
C67.7 Urachus	0.000	0.997	0.003
S92.7 Multiple fractures of foot	0.000	0.997	0.003
C68.9 Urinary organ, unspecified	0.000	0.997	0.003
R68.3 Clubbing of fingers	0.003	0.997	0.000
M54.36 Sciatica (Lumbar region)	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.997	0.003
S98.3 Traumatic amputation of other parts of foot	0.000	0.997	0.003
S98.2 Traumatic amputation of two or more toes	0.000	0.997	0.003
S98.0 Traumatic amputation of foot at ankle level	0.000	0.997	0.003
S92.10 Fracture of talus (closed)	0.000	0.997	0.003
C68.8 Overlapping lesion of urinary organs	0.000	0.997	0.003
C68.1 Paraurethral glands	0.000	0.997	0.003
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.000	0.997	0.003
I06 Rheumatic aortic valve diseases	0.003	0.997	0.000
R68.2 Dry mouth, unspecified	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.997	0.003
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.997	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.997	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.997	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.997	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.997	0.002
S94.1 Injury of medial plantar nerve	0.000	0.997	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.997	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.997	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.997	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.997	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.997	0.002
S95.1 Injury of plantar artery of foot	0.000	0.997	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.997	0.002
C66 Malignant neoplasm of ureter	0.000	0.997	0.002
N50.1 Vascular disorders of male genital organs	0.003	0.997	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.997	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.997	0.002
S92.0 Fracture of calcaneus	0.001	0.997	0.002
Z82.3 Family history of stroke	0.000	0.997	0.003
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.997	0.002
I06.0 Rheumatic aortic stenosis	0.002	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.997	0.002
S92.11 Fracture of talus (open)	0.000	0.997	0.002
K63.1 Perforation of intestine (nontraumatic)	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.000	0.997	0.002
S92.91 Fracture of foot, unspecified (open)	0.000	0.997	0.002
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
C67.1 Dome of bladder	0.000	0.997	0.002
C68.0 Urethra	0.000	0.998	0.002
N39.9 Disorder of urinary system, unspecified	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
C67.8 Overlapping lesion of bladder	0.000	0.998	0.002
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.002	0.998	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
K76.7 Hepatorenal syndrome	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.000	0.998	0.002
C67.6 Ureteric orifice	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.002	0.998	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.998	0.002
K75 Other inflammatory liver diseases	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.002
Z86.6 Personal history of diseases of the nervous system and sense organs	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.002	0.998	0.000
L71.1 Rhinophyma	0.000	0.998	0.002
I05.0 Mitral stenosis	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.001
H40.2 Primary angle-closure glaucoma	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.002	0.998	0.000
R54 Senility	0.002	0.998	0.000
K66.0 Peritoneal adhesions	0.000	0.998	0.002
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
K70 Alcoholic liver disease	0.002	0.998	0.000
N50.0 Atrophy of testis	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.002	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.001
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
K66.1 Haemoperitoneum	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
J95.0 Tracheostomy malfunction	0.002	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
K73.9 Chronic hepatitis, unspecified	0.001	0.998	0.000
N18.0 End-stage renal disease	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.001	0.998	0.001
Z89.2 Acquired absence of upper limb above wrist	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
Z92.8 Personal history of other medical treatment	0.002	0.998	0.000
L03 Cellulitis	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
D32.9 Meninges, unspecified	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
N20.1 Calculus of ureter	0.002	0.998	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.001
N50 Other disorders of male genital organs	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.000	0.998	0.001
L71.8 Other rosacea	0.000	0.998	0.001
H43-H45 Disorders of vitreous body and globe	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.000	0.998	0.002
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.000	0.998	0.001
L71.0 Perioral dermatitis	0.000	0.998	0.001
N48.8 Other specified disorders of penis	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.001
F25.9 Schizoaffective disorder, unspecified	0.001	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.000	0.998	0.001
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.001
L03.9 Cellulitis, unspecified	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.001	0.998	0.000
N48.0 Leukoplakia of penis	0.001	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.001
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations