TreeWAS – Variant ID: rs79336250

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
E11.9 Without complications	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001
E10-E14 Diabetes mellitus	0.999	0.001
Chapter X Diseases of the respiratory system	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
I60-I69 Cerebrovascular diseases	0.998	0.002
J30-J39 Other diseases of upper respiratory tract	0.997	0.003
I20-I25 Ischaemic heart diseases	0.994	0.006
I20 Angina pectoris	0.994	0.006
Chapter V Mental and behavioural disorders	0.989	0.011
I20.9 Angina pectoris, unspecified	0.988	0.012
D10-D36 Benign neoplasms	0.986	0.014
Chapter II Neoplasms	0.984	0.016
I70-I79 Diseases of arteries, arterioles and capillaries	0.983	0.017
M20-M25 Other joint disorders	0.978	0.022
J34 Other disorders of nose and nasal sinuses	0.976	0.024
J40-J47 Chronic lower respiratory diseases	0.974	0.026
D17 Benign lipomatous neoplasm	0.974	0.026
I63 Cerebral infarction	0.973	0.027
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.972	0.028
J44 Other chronic obstructive pulmonary disease	0.971	0.029
M70-M79 Other soft tissue disorders	0.970	0.030
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.969	0.031
I77 Other disorders of arteries and arterioles	0.965	0.035
M45-M49 Spondylopathies	0.964	0.036
R07 Pain in throat and chest	0.964	0.036
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.963	0.037
R07.2 Precordial pain	0.963	0.037
I64 Stroke, not specified as haemorrhage or infarction	0.962	0.038
I20.0 Unstable angina	0.959	0.041
M75 Shoulder lesions	0.957	0.043
I63.9 Cerebral infarction, unspecified	0.956	0.044
R79 Other abnormal findings of blood chemistry	0.954	0.046
R30-R39 Symptoms and signs involving the urinary system	0.949	0.051
R79.8 Other specified abnormal findings of blood chemistry	0.941	0.059
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.939	0.061
F00-F09 Organic, including symptomatic, mental disorders	0.937	0.063
J34.8 Other specified disorders of nose and nasal sinuses	0.936	0.064
E65-E68 Obesity and other hyperalimentation	0.935	0.065
C51-C58 Malignant neoplasms of female genital organs	0.934	0.066
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.933	0.067
Chapter VII Diseases of the eye and adnexa	0.930	0.070
I77.9 Disorder of arteries and arterioles, unspecified	0.928	0.072
M46 Other inflammatory spondylopathies	0.924	0.076
J44.9 Chronic obstructive pulmonary disease, unspecified	0.922	0.078
J34.3 Hypertrophy of nasal turbinates	0.910	0.090
R06 Abnormalities of breathing	0.909	0.091
D35 Benign neoplasm of other and unspecified endocrine glands	0.906	0.094
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.905	0.095
M23 Internal derangement of knee	0.904	0.096
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.904	0.096
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.903	0.097
R39 Other symptoms and signs involving the urinary system	0.903	0.097
J35 Chronic diseases of tonsils and adenoids	0.903	0.097
R41 Other symptoms and signs involving cognitive functions and awareness	0.897	0.103
M24 Other specific joint derangements	0.896	0.104
D14 Benign neoplasm of middle ear and respiratory system	0.894	0.106
M75.1 Rotator cuff syndrome	0.894	0.106
M46.9 Inflammatory spondylopathy, unspecified	0.892	0.108
H43-H45 Disorders of vitreous body and globe	0.891	0.109
R06.0 Dyspnoea	0.890	0.110
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.889	0.111
E66 Obesity	0.888	0.112
M23.3 Other meniscus derangements	0.886	0.114
F40-F48 Neurotic, stress-related and somatoform disorders	0.886	0.114
J32 Chronic sinusitis	0.886	0.114
M75.4 Impingement syndrome of shoulder	0.882	0.118
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.881	0.119
D22 Melanocytic naevi	0.878	0.122
J47 Bronchiectasis	0.875	0.125
R35 Polyuria	0.873	0.127
M75.3 Calcific tendinitis of shoulder	0.872	0.128
F03 Unspecified dementia	0.865	0.135
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.865	0.135
D23 Other benign neoplasms of skin	0.864	0.136
R30 Pain associated with micturition	0.859	0.141
D11 Benign neoplasm of major salivary glands	0.858	0.142
I74 Arterial embolism and thrombosis	0.857	0.143
H43 Disorders of vitreous body	0.856	0.144
C53 Malignant neoplasm of cervix uteri	0.851	0.149
I20.8 Other forms of angina pectoris	0.847	0.153
J39 Other diseases of upper respiratory tract	0.845	0.155
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.844	0.156
R80 Isolated proteinuria	0.843	0.157
J30 Vasomotor and allergic rhinitis	0.843	0.157
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.842	0.158
R94 Abnormal results of function studies	0.841	0.159
D34 Benign neoplasm of thyroid gland	0.840	0.160
Chapter I Certain infectious and parasitic diseases	0.836	0.164
J00-J06 Acute upper respiratory infections	0.834	0.166
I71 Aortic aneurysm and dissection	0.832	0.168
M40-M43 Deforming dorsopathies	0.832	0.168
D17.9 Benign lipomatous neoplasm, unspecified	0.830	0.170
M25 Other joint disorders, not elsewhere classified	0.829	0.171
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.828	0.172
I77.1 Stricture of artery	0.828	0.172
R93 Abnormal findings on diagnostic imaging of other body structures	0.828	0.172
D36 Benign neoplasm of other and unspecified sites	0.826	0.174
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.825	0.175
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.821	0.179
E66.9 Obesity, unspecified	0.820	0.180
I60 Subarachnoid haemorrhage	0.819	0.181
D35.1 Parathyroid gland	0.817	0.182
R41.3 Other amnesia	0.815	0.185
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.815	0.185
M22 Disorders of patella	0.815	0.185
I27 Other pulmonary heart diseases	0.815	0.185
M80-M85 Disorders of bone density and structure	0.814	0.186
I67 Other cerebrovascular diseases	0.810	0.190
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.810	0.190
R07.4 Chest pain, unspecified	0.809	0.191
R45 Symptoms and signs involving emotional state	0.807	0.193
I62 Other nontraumatic intracranial haemorrhage	0.803	0.197
E11.0 With coma	0.799	0.201
D14.0 Middle ear, nasal cavity and accessory sinuses	0.798	0.202
M24.1 Other articular cartilage disorders	0.797	0.203
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.796	0.204
C51 Malignant neoplasm of vulva	0.795	0.205
M31 Other necrotising vasculopathies	0.794	0.205
D23.1 Skin of eyelid, including canthus	0.793	0.207
I77.0 Arteriovenous fistula, acquired	0.792	0.208
C53.9 Cervix uteri, unspecified	0.792	0.208
M47 Spondylosis	0.789	0.211
D33 Benign neoplasm of brain and other parts of central nervous system	0.788	0.212
M45 Ankylosing spondylitis	0.788	0.212
R94.5 Abnormal results of liver function studies	0.788	0.212
R01 Cardiac murmurs and other cardiac sounds	0.786	0.214
E20-E35 Disorders of other endocrine glands	0.785	0.215
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.783	0.217
R30.0 Dysuria	0.782	0.218
I61 Intracerebral haemorrhage	0.782	0.218
J33 Nasal polyp	0.781	0.219
H43.8 Other disorders of vitreous body	0.780	0.219
D28 Benign neoplasm of other and unspecified female genital organs	0.779	0.221
F41 Other anxiety disorders	0.778	0.222
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.777	0.223
J34.1 Cyst and mucocele of nose and nasal sinus	0.777	0.223
H46-H48 Disorders of optic nerve and visual pathways	0.776	0.224
E11.2 With renal complications	0.775	0.225
E11.8 With unspecified complications	0.775	0.225
D22.1 Melanocytic naevi of eyelid, including canthus	0.775	0.225
E11.4 With neurological complications	0.774	0.226
F43 Reaction to severe stress, and adjustment disorders	0.772	0.228
H50 Other strabismus	0.771	0.229
M71 Other bursopathies	0.771	0.229
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.770	0.230
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.769	0.231
I05-I09 Chronic rheumatic heart diseases	0.768	0.232
I10-I15 Hypertensive diseases	0.767	0.233
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.766	0.234
E11.1 With ketoacidosis	0.765	0.235
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.762	0.238
D18 Haemangioma and lymphangioma, any site	0.762	0.238
J32.8 Other chronic sinusitis	0.761	0.239
J35.0 Chronic tonsillitis	0.761	0.239
E66.0 Obesity due to excess calories	0.761	0.239
Chapter VI Diseases of the nervous system	0.761	0.239
R71 Abnormality of red blood cells	0.760	0.240
A30-A49 Other bacterial diseases	0.760	0.240
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.759	0.241
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.758	0.242
Chapter XXII Codes for special purposes	0.758	0.242
D26 Other benign neoplasms of uterus	0.758	0.242
R07.1 Chest pain on breathing	0.757	0.243
M21 Other acquired deformities of limbs	0.757	0.243
C54 Malignant neoplasm of corpus uteri	0.756	0.244
M50-M54 Other dorsopathies	0.753	0.247
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.751	0.249
D32 Benign neoplasm of meninges	0.751	0.249
J35.1 Hypertrophy of tonsils	0.751	0.249
J44.8 Other specified chronic obstructive pulmonary disease	0.750	0.250
J36 Peritonsillar abscess	0.748	0.252
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.746	0.254
E40-E46 Malnutrition	0.745	0.254
D22.2 Melanocytic naevi of ear and external auricular canal	0.746	0.254
D30 Benign neoplasm of urinary organs	0.745	0.255
D24 Benign neoplasm of breast	0.744	0.256
E14 Unspecified diabetes mellitus	0.742	0.258
R26 Abnormalities of gait and mobility	0.742	0.258
B15-B19 Viral hepatitis	0.739	0.261
H10-H13 Disorders of conjunctiva	0.737	0.263
D29 Benign neoplasm of male genital organs	0.737	0.263
F60-F69 Disorders of adult personality and behaviour	0.736	0.264
F05 Delirium, not induced by alcohol and other psychoactive substances	0.736	0.264
C55 Malignant neoplasm of uterus, part unspecified	0.736	0.264
I27.0 Primary pulmonary hypertension	0.734	0.266
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.733	0.267
F20 Schizophrenia	0.731	0.269
D23.4 Skin of scalp and neck	0.730	0.270
M47.2 Other spondylosis with radiculopathy	0.727	0.273
M75.2 Bicipital tendinitis	0.727	0.273
H55-H59 Other disorders of eye and adnexa	0.725	0.275
R91 Abnormal findings on diagnostic imaging of lung	0.724	0.276
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.724	0.276
F99-F99 Unspecified mental disorder	0.723	0.277
D11.0 Parotid gland	0.722	0.278
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.722	0.278
D14.1 Larynx	0.721	0.279
H43.1 Vitreous haemorrhage	0.719	0.281
I72 Other aneurysm	0.719	0.281
J32.0 Chronic maxillary sinusitis	0.719	0.281
J39.8 Other specified diseases of upper respiratory tract	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
E11.7 With multiple complications	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.716	0.284
M60-M63 Disorders of muscles	0.716	0.284
E11.6 With other specified complications	0.716	0.284
F80-F89 Disorders of psychological development	0.716	0.284
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.716	0.284
I68 Cerebrovascular disorders in diseases classified elsewhere	0.715	0.285
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.715	0.285
M76 Enthesopathies of lower limb, excluding foot	0.715	0.285
H43.3 Other vitreous opacities	0.713	0.287
I23 Certain current complications following acute myocardial infarction	0.713	0.287
F25 Schizoaffective disorders	0.713	0.287
M91-M94 Chondropathies	0.712	0.288
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.711	0.289
D35.0 Adrenal gland	0.710	0.290
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.709	0.291
F70-F79 Mental retardation	0.709	0.291
J37 Chronic laryngitis and laryngotracheitis	0.708	0.292
D21 Other benign neoplasms of connective and other soft tissue	0.708	0.292
F01 Vascular dementia	0.708	0.292
H50.1 Divergent concomitant strabismus	0.707	0.293
R06.5 Mouth breathing	0.707	0.293
D31 Benign neoplasm of eye and adnexa	0.707	0.293
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.707	0.293
D19 Benign neoplasm of mesothelial tissue	0.707	0.293
D16 Benign neoplasm of bone and articular cartilage	0.707	0.293
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.707	0.293
I27.2 Other secondary pulmonary hypertension	0.706	0.294
J90-J94 Other diseases of pleura	0.706	0.294
M25.6 Stiffness of joint, not elsewhere classified	0.706	0.294
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.706	0.294
C40-C41 Malignant neoplasms of bone and articular cartilage	0.706	0.294
M22.4 Chondromalacia patellae	0.706	0.294
F00 Dementia in Alzheimer's disease	0.705	0.295
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.705	0.295
M05-M14 Inflammatory polyarthropathies	0.704	0.296
M23.9 Internal derangement of knee, unspecified	0.703	0.297
E13 Other specified diabetes mellitus	0.703	0.297
J60-J70 Lung diseases due to external agents	0.703	0.297
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.702	0.298
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.702	0.298
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.702	0.298
I24 Other acute ischaemic heart diseases	0.702	0.298
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.701	0.298
M33 Dermatopolymyositis	0.701	0.298
M32 Systemic lupus erythematosus	0.701	0.298
M30 Polyarteritis nodosa and related conditions	0.701	0.298
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.701	0.299
M24.5 Contracture of joint	0.700	0.300
F41.2 Mixed anxiety and depressive disorder	0.700	0.300
R47-R49 Symptoms and signs involving speech and voice	0.699	0.301
M86-M90 Other osteopathies	0.699	0.301
M46.4 Discitis, unspecified	0.698	0.302
J41 Simple and mucopurulent chronic bronchitis	0.698	0.302
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.698	0.302
M00-M03 Infectious arthropathies	0.698	0.302
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.698	0.302
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.698	0.302
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.698	0.302
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.698	0.302
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.698	0.302
M70 Soft tissue disorders related to use, overuse and pressure	0.697	0.303
R78 Findings of drugs and other substances, not normally found in blood	0.697	0.303
R77 Other abnormalities of plasma proteins	0.697	0.303
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.697	0.303
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.697	0.303
J35.8 Other chronic diseases of tonsils and adenoids	0.697	0.303
E50-E64 Other nutritional deficiencies	0.696	0.304
I67.2 Cerebral atherosclerosis	0.696	0.304
M73 Soft tissue disorders in diseases classified elsewhere	0.695	0.305
R73 Elevated blood glucose level	0.695	0.305
Chapter XX External causes of morbidity and mortality	0.695	0.305
C51.9 Vulva, unspecified	0.694	0.306
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.694	0.306
D11.9 Major salivary gland, unspecified	0.694	0.306
J34.0 Abscess, furuncle and carbuncle of nose	0.694	0.306
R79.0 Abnormal level of blood mineral	0.694	0.306
J80-J84 Other respiratory diseases principally affecting the interstitium	0.693	0.307
I77.8 Other specified disorders of arteries and arterioles	0.692	0.308
I77.5 Necrosis of artery	0.692	0.308
I77.4 Coeliac artery compression syndrome	0.692	0.308
I77.3 Arterial fibromuscular dysplasia	0.692	0.308
I77.2 Rupture of artery	0.692	0.308
Chapter XII Diseases of the skin and subcutaneous tissue	0.692	0.308
M23.30 Other meniscus derangements (Multiple sites)	0.691	0.309
M49 Spondylopathies in diseases classified elsewhere	0.691	0.309
M54 Dorsalgia	0.691	0.309
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.691	0.309
D35.2 Pituitary gland	0.690	0.310
F22 Persistent delusional disorders	0.690	0.310
R01.0 Benign and innocent cardiac murmurs	0.690	0.310
R46 Symptoms and signs involving appearance and behaviour	0.689	0.311
J06 Acute upper respiratory infections of multiple and unspecified sites	0.689	0.311
R32 Unspecified urinary incontinence	0.689	0.311
C64-C68 Malignant neoplasms of urinary tract	0.688	0.312
H44 Disorders of globe	0.688	0.312
J46 Status asthmaticus	0.686	0.314
M75.8 Other shoulder lesions	0.686	0.314
M75.9 Shoulder lesion, unspecified	0.686	0.314
D22.6 Melanocytic naevi of upper limb, including shoulder	0.686	0.314
A49 Bacterial infection of unspecified site	0.686	0.314
R79.9 Abnormal finding of blood chemistry, unspecified	0.684	0.316
Q20-Q28 Congenital malformations of the circulatory system	0.684	0.316
R26.8 Other and unspecified abnormalities of gait and mobility	0.684	0.316
G20-G26 Extrapyramidal and movement disorders	0.684	0.316
M24.8 Other specific joint derangements, not elsewhere classified	0.683	0.317
R45.2 Unhappiness	0.683	0.317
R74 Abnormal serum enzyme levels	0.683	0.317
R39.1 Other difficulties with micturition	0.683	0.317
I25 Chronic ischaemic heart disease	0.682	0.318
R36 Urethral discharge	0.680	0.320
R34 Anuria and oliguria	0.680	0.320
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.680	0.320
M34 Systemic sclerosis	0.679	0.321
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.679	0.321
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.676	0.324
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.676	0.324
M43 Other deforming dorsopathies	0.676	0.324
D36.7 Other specified sites	0.675	0.325
I10 Essential (primary) hypertension	0.675	0.325
D17.7 Benign lipomatous neoplasm of other sites	0.675	0.325
R92 Abnormal findings on diagnostic imaging of breast	0.673	0.327
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.673	0.327
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.672	0.328
F02 Dementia in other diseases classified elsewhere	0.672	0.328
F09 Unspecified organic or symptomatic mental disorder	0.672	0.328
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.672	0.328
D23.2 Skin of ear and external auricular canal	0.671	0.328
J33.9 Nasal polyp, unspecified	0.671	0.329
E67 Other hyperalimentation	0.670	0.330
E68 Sequelae of hyperalimentation	0.670	0.330
E65 Localised adiposity	0.670	0.330
C57 Malignant neoplasm of other and unspecified female genital organs	0.670	0.330
C58 Malignant neoplasm of placenta	0.670	0.330
C52 Malignant neoplasm of vagina	0.670	0.330
I30-I52 Other forms of heart disease	0.670	0.330
M24.4 Recurrent dislocation and subluxation of joint	0.669	0.331
R43 Disturbances of smell and taste	0.669	0.331
R40 Somnolence, stupor and coma	0.669	0.331
R45.1 Restlessness and agitation	0.669	0.331
J30.1 Allergic rhinitis due to pollen	0.668	0.332
R44 Other symptoms and signs involving general sensations and perceptions	0.666	0.334
M24.16 Other articular cartilage disorders (Lower leg)	0.666	0.334
I70 Atherosclerosis	0.666	0.334
I77.6 Arteritis, unspecified	0.666	0.334
J30.4 Allergic rhinitis, unspecified	0.664	0.336
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.664	0.336
D23.5 Skin of trunk	0.664	0.336
F23 Acute and transient psychotic disorders	0.663	0.336
M46.8 Other specified inflammatory spondylopathies	0.663	0.337
M46.5 Other infective spondylopathies	0.663	0.337
M46.3 Infection of intervertebral disk (pyogenic)	0.663	0.337
M46.2 Osteomyelitis of vertebra	0.663	0.337
M46.1 Sacro-iliitis, not elsewhere classified	0.663	0.337
M46.0 Spinal enthesopathy	0.663	0.337
M31.6 Other giant cell arteritis	0.663	0.337
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.662	0.338
I78 Diseases of capillaries	0.661	0.339
R41.0 Disorientation, unspecified	0.661	0.339
I82 Other venous embolism and thrombosis	0.660	0.340
F29 Unspecified nonorganic psychosis	0.658	0.342
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.658	0.342
R30.9 Painful micturition, unspecified	0.658	0.342
F20.9 Schizophrenia, unspecified	0.657	0.343
H47 Other disorders of optic [2nd] nerve and visual pathways	0.656	0.344
M84 Disorders of continuity of bone	0.656	0.344
F30-F39 Mood [affective] disorders	0.656	0.344
J32.4 Chronic pansinusitis	0.655	0.345
I71.0 Dissection of aorta [any part]	0.655	0.345
M54.5 Low back pain	0.653	0.347
M80 Osteoporosis with pathological fracture	0.653	0.347
R06.7 Sneezing	0.652	0.348
R06.6 Hiccough	0.652	0.348
R06.3 Periodic breathing	0.652	0.348
R72 Abnormality of white blood cells, not elsewhere classified	0.651	0.348
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.650	0.349
M41 Scoliosis	0.651	0.349
M24.11 Other articular cartilage disorders (Shoulder region)	0.650	0.350
D35.9 Endocrine gland, unspecified	0.650	0.350
D35.8 Pluriglandular involvement	0.650	0.350
D35.7 Other specified endocrine glands	0.650	0.350
D35.6 Aortic body and other paraganglia	0.650	0.350
D35.5 Carotid body	0.650	0.350
D35.4 Pineal gland	0.650	0.350
D35.3 Craniopharyngeal duct	0.650	0.350
R76 Other abnormal immunological findings in serum	0.649	0.351
D36.1 Peripheral nerves and autonomic nervous system	0.649	0.351
L00-L08 Infections of the skin and subcutaneous tissue	0.649	0.351
M23.1 Discoid meniscus (congenital)	0.648	0.352
M23.0 Cystic meniscus	0.648	0.352
M23.6 Other spontaneous disruption of ligament(s) of knee	0.648	0.352
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.648	0.352
E66.8 Other obesity	0.648	0.352
R39.2 Extrarenal uraemia	0.647	0.353
R39.0 Extravasation of urine	0.647	0.353
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.647	0.353
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.647	0.353
J35.2 Hypertrophy of adenoids	0.647	0.353
M77 Other enthesopathies	0.647	0.353
I67.8 Other specified cerebrovascular diseases	0.646	0.354
R41.2 Retrograde amnesia	0.643	0.357
R41.1 Anterograde amnesia	0.643	0.357
M24.9 Joint derangement, unspecified	0.642	0.358
M24.7 Protrusio acetabuli	0.642	0.358
M24.6 Ankylosis of joint	0.642	0.358
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.642	0.358
M24.2 Disorder of ligament	0.642	0.358
C83 Diffuse non-Hodgkin's lymphoma	0.642	0.358
J02 Acute pharyngitis	0.642	0.358
J30.3 Other allergic rhinitis	0.641	0.358
D14.4 Respiratory system, unspecified	0.641	0.359
D14.3 Bronchus and lung	0.641	0.359
D14.2 Trachea	0.641	0.359
H52 Disorders of refraction and accommodation	0.640	0.360
J39.2 Other diseases of pharynx	0.640	0.360
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.639	0.361
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.639	0.361
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.639	0.361
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.639	0.361
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.639	0.361
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.639	0.361
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.639	0.361
M75.5 Bursitis of shoulder	0.639	0.361
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.639	0.361
D22.7 Melanocytic naevi of lower limb, including hip	0.638	0.362
H50.0 Convergent concomitant strabismus	0.638	0.362
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.638	0.362
M54.59 Low back pain (Site unspecified)	0.637	0.363
F28 Other nonorganic psychotic disorders	0.637	0.363
F24 Induced delusional disorder	0.637	0.363
F21 Schizotypal disorder	0.637	0.363
I50 Heart failure	0.637	0.363
E66.2 Extreme obesity with alveolar hypoventilation	0.637	0.363
E66.1 Drug-induced obesity	0.637	0.363
R81 Glycosuria	0.636	0.364
F43.2 Adjustment disorders	0.636	0.364
M25.0 Haemarthrosis	0.636	0.364
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.636	0.364
D22.0 Melanocytic naevi of lip	0.636	0.364
M23.37 Other meniscus derangements-Capsular lig	0.635	0.364
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.635	0.364
F48 Other neurotic disorders	0.635	0.365
F44 Dissociative [conversion] disorders	0.635	0.365
J32.3 Chronic sphenoidal sinusitis	0.635	0.365
J32.1 Chronic frontal sinusitis	0.635	0.365
M25.7 Osteophyte	0.635	0.365
R06.1 Stridor	0.634	0.365
R82 Other abnormal findings in urine	0.634	0.366
E11.3 With ophthalmic complications	0.634	0.366
J92 Pleural plaque	0.634	0.366
M24.0 Loose body in joint	0.633	0.367
I05 Rheumatic mitral valve diseases	0.633	0.367
D22.4 Melanocytic naevi of scalp and neck	0.633	0.367
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.633	0.367
E11.5 With peripheral circulatory complications	0.632	0.368
G20 Parkinson's disease	0.632	0.368
I28 Other diseases of pulmonary vessels	0.632	0.368
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.632	0.368
A46 Erysipelas	0.631	0.369
J32.2 Chronic ethmoidal sinusitis	0.631	0.369
E14.9 Without complications	0.631	0.369
D22.9 Melanocytic naevi, unspecified	0.630	0.370
C90 Multiple myeloma and malignant plasma cell neoplasms	0.629	0.371
R06.4 Hyperventilation	0.628	0.372
C54.1 Endometrium	0.628	0.372
M71.2 Synovial cyst of popliteal space [Baker]	0.628	0.372
J32.9 Chronic sinusitis, unspecified	0.627	0.373
I61.9 Intracerebral haemorrhage, unspecified	0.627	0.373
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.627	0.373
D28.2 Uterine tubes and ligaments	0.627	0.373
F43.0 Acute stress reaction	0.626	0.374
M45.X9 Ankylosing spondylitis (Site unspecified)	0.626	0.374
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.625	0.375
A40 Streptococcal septicaemia	0.625	0.375
M25.9 Joint disorder, unspecified	0.624	0.376
D33.2 Brain, unspecified	0.624	0.376
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.624	0.376
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.623	0.377
B65-B83 Helminthiases	0.620	0.380
D23.9 Skin, unspecified	0.620	0.380
D23.0 Skin of lip	0.620	0.380
M47.1 Other spondylosis with myelopathy	0.619	0.381
E22 Hyperfunction of pituitary gland	0.618	0.382
I25.2 Old myocardial infarction	0.617	0.383
R30.1 Vesical tenesmus	0.616	0.384
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.616	0.384
M85 Other disorders of bone density and structure	0.616	0.384
D11.7 Other major salivary glands	0.615	0.385
J20-J22 Other acute lower respiratory infections	0.615	0.385
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.614	0.386
I74.9 Embolism and thrombosis of unspecified artery	0.614	0.386

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations