TreeWAS – Variant ID: rs79588679

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.001	0.999
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.003	0.997
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.004	0.996
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.015	0.985
T39.1 4-Aminophenol derivatives	0.000	0.015	0.985
T43.2 Other and unspecified antidepressants	0.000	0.021	0.979
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.052	0.948
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.069	0.931
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.089	0.911
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.093	0.907
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.102	0.898
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.112	0.888
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.141	0.859
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.159	0.841
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.163	0.837
T40.2 Other opioids	0.000	0.176	0.824
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.191	0.809
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.193	0.807
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.242	0.758
T43.6 Psychostimulants with abuse potential	0.000	0.242	0.758
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.246	0.754
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.249	0.751
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.249	0.751
T40.4 Other synthetic narcotics	0.000	0.252	0.748
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.260	0.740
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.263	0.737
T39.0 Salicylates	0.000	0.267	0.733
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.284	0.716
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.284	0.716
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.284	0.716
T42.4 Benzodiazepines	0.000	0.285	0.715
T43.9 Psychotropic drug, unspecified	0.000	0.285	0.715
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.285	0.715
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.285	0.715
T39.4 Antirheumatics, not elsewhere classified	0.000	0.286	0.714
T39.2 Pyrazolone derivatives	0.000	0.286	0.714
T45.0 Antiallergic and antiemetic drugs	0.000	0.291	0.709
T45.5 Anticoagulants	0.000	0.296	0.704
T46.1 Calcium-channel blockers	0.000	0.309	0.691
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.309	0.691
T36 Poisoning by systemic antibiotics	0.000	0.314	0.686
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.320	0.679
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.320	0.679
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.320	0.679
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.320	0.679
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.320	0.679
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.320	0.679
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.320	0.679
T44.0 Anticholinesterase agents	0.000	0.320	0.679
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.325	0.675
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.339	0.661
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.347	0.653
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.347	0.653
T46.7 Peripheral vasodilators	0.000	0.347	0.653
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.347	0.653
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.347	0.653
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.350	0.650
T40.8 Lysergide [LSD]	0.000	0.350	0.650
T40.7 Cannabis (derivatives)	0.000	0.350	0.650
T40.5 Cocaine	0.000	0.350	0.650
T40.3 Methadone	0.000	0.350	0.650
T40.1 Heroin	0.000	0.350	0.650
T40.0 Opium	0.000	0.350	0.650
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.363	0.637
T45.8 Other primarily systemic and haematological agents	0.000	0.363	0.637
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.363	0.637
T45.6 Fibrinolysis-affecting drugs	0.000	0.363	0.637
T45.4 Iron and its compounds	0.000	0.363	0.637
T45.3 Enzymes, not elsewhere classified	0.000	0.363	0.637
T45.2 Vitamins, not elsewhere classified	0.000	0.363	0.637
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.371	0.628
T38.9 Other and unspecified hormone antagonists	0.000	0.384	0.616
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.384	0.616
T38.7 Androgens and anabolic congeners	0.000	0.384	0.616
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.384	0.616
T38.5 Other oestrogens and progestogens	0.000	0.384	0.616
T38.4 Oral contraceptives	0.000	0.384	0.616
T38.2 Antithyroid drugs	0.000	0.384	0.616
T38.1 Thyroid hormones and substitutes	0.000	0.384	0.616
T38.0 Glucocorticoids and synthetic analogues	0.000	0.384	0.616
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.397	0.603
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.397	0.603
T42.2 Succinimides and oxazolidinediones	0.000	0.397	0.603
T50.8 Diagnostic agents	0.000	0.400	0.600
T50.7 Analeptics and opioid receptor antagonists	0.000	0.400	0.600
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.400	0.600
T50.5 Appetite depressants	0.000	0.400	0.600
T50.4 Drugs affecting uric acid metabolism	0.000	0.400	0.600
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.400	0.600
T50.1 Loop [high-ceiling] diuretics	0.000	0.400	0.600
T50.0 Mineralocorticoids and their antagonists	0.000	0.400	0.600
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.403	0.597
T42.1 Iminostilbenes	0.000	0.411	0.588
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.413	0.587
T42.0 Hydantoin derivatives	0.000	0.419	0.581
T40.6 Other and unspecified narcotics	0.000	0.428	0.572
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.432	0.568
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.432	0.568
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.445	0.555
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.455	0.545
T41.5 Therapeutic gases	0.000	0.486	0.513
T41.4 Anaesthetic, unspecified	0.000	0.486	0.513
T41.3 Local anaesthetics	0.000	0.486	0.513
T41.2 Other and unspecified general anaesthetics	0.000	0.486	0.513
T41.1 Intravenous anaesthetics	0.000	0.486	0.513
T41.0 Inhaled anaesthetics	0.000	0.486	0.513
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.486	0.513
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.486	0.513
T48.5 Anti-common-cold drugs	0.000	0.486	0.513
T48.4 Expectorants	0.000	0.486	0.513
T48.3 Antitussives	0.000	0.486	0.513
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.486	0.513
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.486	0.513
T48.0 Oxytocic drugs	0.000	0.486	0.513
T49.9 Topical agent, unspecified	0.000	0.486	0.513
T49.8 Other topical agents	0.000	0.486	0.513
T49.7 Dental drugs, topically applied	0.000	0.486	0.513
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.486	0.513
T49.5 Ophthalmological drugs and preparations	0.000	0.486	0.513
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.486	0.513
T49.3 Emollients, demulcents and protectants	0.000	0.486	0.513
T49.2 Local astringents and local detergents	0.000	0.486	0.513
T49.1 Antipruritics	0.000	0.486	0.513
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.486	0.513
T36.9 Systemic antibiotic, unspecified	0.000	0.508	0.492
T36.8 Other systemic antibiotics	0.000	0.508	0.492
T36.7 Antifungal antibiotics, systemically used	0.000	0.508	0.492
T36.6 Rifamycins	0.000	0.508	0.492
T36.5 Aminoglycosides	0.000	0.508	0.492
T36.4 Tetracyclines	0.000	0.508	0.492
T36.3 Macrolides	0.000	0.508	0.492
T36.2 Chloramphenicol group	0.000	0.508	0.492
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.508	0.492
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.516	0.484
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.516	0.484
T47.7 Emetics	0.000	0.516	0.484
T47.6 Antidiarrhoeal drugs	0.000	0.516	0.484
T47.5 Digestants	0.000	0.516	0.484
T47.4 Other laxatives	0.000	0.516	0.484
T47.3 Saline and osmotic laxatives	0.000	0.516	0.484
T47.2 Stimulant laxatives	0.000	0.516	0.484
T47.0 Histamine H(2)-receptor antagonists	0.000	0.516	0.484
T36.0 Penicillins	0.000	0.537	0.462
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.549	0.450
T37.5 Antiviral drugs	0.000	0.549	0.450
T37.4 Anthelminthics	0.000	0.549	0.450
T37.3 Other antiprotozoal drugs	0.000	0.549	0.450
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.549	0.450
T37.1 Antimycobacterial drugs	0.000	0.549	0.450
T37.0 Sulphonamides	0.000	0.549	0.450
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.557	0.443
T42.3 Barbiturates	0.001	0.585	0.414
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.637	0.363
K75.4 Autoimmune hepatitis	0.024	0.976	0.000
K75 Other inflammatory liver diseases	0.023	0.977	0.000
K75.8 Other specified inflammatory liver diseases	0.022	0.978	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.020	0.980	0.000
D47.1 Chronic myeloproliferative disease	0.020	0.980	0.000
C71.9 Brain, unspecified	0.000	0.981	0.019
K76.6 Portal hypertension	0.019	0.981	0.000
D47.2 Monoclonal gammopathy	0.018	0.982	0.000
K76.9 Liver disease, unspecified	0.018	0.982	0.000
K70-K77 Diseases of liver	0.018	0.982	0.000
K75.0 Abscess of liver	0.018	0.982	0.000
K76 Other diseases of liver	0.017	0.983	0.000
C71 Malignant neoplasm of brain	0.000	0.983	0.017
D47.4 Osteomyelofibrosis	0.017	0.983	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.016	0.983	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.016	0.984	0.000
K75.2 Nonspecific reactive hepatitis	0.016	0.984	0.000
K75.1 Phlebitis of portal vein	0.016	0.984	0.000
C71.2 Temporal lobe	0.000	0.984	0.016
C71.3 Parietal lobe	0.000	0.984	0.016
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.015	0.985	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.014	0.986	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.014	0.986	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.014	0.986	0.000
K66.0 Peritoneal adhesions	0.000	0.986	0.014
C71.1 Frontal lobe	0.000	0.986	0.014
D37.5 Rectum	0.014	0.986	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.014	0.986	0.000
K73 Chronic hepatitis, not elsewhere classified	0.014	0.986	0.000
K71 Toxic liver disease	0.014	0.986	0.000
K76.7 Hepatorenal syndrome	0.013	0.987	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.013	0.987	0.000
C71.8 Overlapping lesion of brain	0.000	0.987	0.013
K70 Alcoholic liver disease	0.013	0.987	0.000
K77 Liver disorders in diseases classified elsewhere	0.013	0.987	0.000
K65.0 Acute peritonitis	0.000	0.987	0.013
K76.5 Hepatic veno-occlusive disease	0.013	0.987	0.000
K76.4 Peliosis hepatis	0.013	0.987	0.000
K76.3 Infarction of liver	0.013	0.987	0.000
K76.2 Central haemorrhagic necrosis of liver	0.013	0.987	0.000
K76.1 Chronic passive congestion of liver	0.013	0.987	0.000
K72 Hepatic failure, not elsewhere classified	0.013	0.987	0.000
C71.7 Brain stem	0.000	0.987	0.012
C71.6 Cerebellum	0.000	0.987	0.012
C71.5 Cerebral ventricle	0.000	0.987	0.012
K01.1 Impacted teeth	0.013	0.987	0.000
K66 Other disorders of peritoneum	0.000	0.988	0.012
K75.9 Inflammatory liver disease, unspecified	0.012	0.988	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.988	0.012
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.012	0.988	0.000
K73.9 Chronic hepatitis, unspecified	0.012	0.988	0.000
C71.4 Occipital lobe	0.000	0.988	0.012
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.012	0.988	0.000
K70.3 Alcoholic cirrhosis of liver	0.012	0.988	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.011	0.989	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.011	0.989	0.000
K65 Peritonitis	0.000	0.989	0.011
Y42.5 Other oestrogens and progestogens	0.011	0.989	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.011	0.989	0.000
D37.0 Lip, oral cavity and pharynx	0.011	0.989	0.000
Y42.7 Androgens and anabolic congeners	0.011	0.989	0.000
Y57 Other and unspecified drugs and medicaments	0.011	0.989	0.000
Y57.5 X-ray contrast media	0.011	0.989	0.000
D46 Myelodysplastic syndromes	0.010	0.989	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.010	0.990	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.010	0.990	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.990	0.010
D45 Polycythaemia vera	0.010	0.990	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.010	0.990	0.000
K70.9 Alcoholic liver disease, unspecified	0.010	0.990	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.010	0.990	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.010	0.990	0.000
K65-K67 Diseases of peritoneum	0.000	0.990	0.010
K71.9 Toxic liver disease, unspecified	0.010	0.990	0.000
K71.8 Toxic liver disease with other disorders of liver	0.010	0.990	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.010	0.990	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.010	0.990	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.010	0.990	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.010	0.990	0.000
K71.2 Toxic liver disease with acute hepatitis	0.010	0.990	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.010	0.990	0.000
K71.0 Toxic liver disease with cholestasis	0.010	0.990	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.010	0.990	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.010	0.990	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.010	0.990	0.000
I85.9 Oesophageal varices without bleeding	0.010	0.990	0.000
D37.9 Digestive organ, unspecified	0.010	0.990	0.000
D39.1 Ovary	0.010	0.990	0.000
K66.1 Haemoperitoneum	0.000	0.990	0.010
D37.1 Stomach	0.010	0.990	0.000
D43.1 Brain, infratentorial	0.010	0.990	0.000
D37.3 Appendix	0.010	0.990	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.010	0.990	0.000
D37.4 Colon	0.010	0.990	0.000
K72.0 Acute and subacute hepatic failure	0.010	0.990	0.000
D43.2 Brain, unspecified	0.010	0.990	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.009	0.990	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.009	0.990	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.009	0.990	0.000
K74 Fibrosis and cirrhosis of liver	0.009	0.990	0.000
K72.1 Chronic hepatic failure	0.009	0.991	0.000
D37.2 Small intestine	0.009	0.991	0.000
D44.6 Carotid body	0.009	0.991	0.000
K65.9 Peritonitis, unspecified	0.000	0.991	0.009
K73.2 Chronic active hepatitis, not elsewhere classified	0.009	0.991	0.000
Y45.1 Salicylates	0.009	0.991	0.000
K72.9 Hepatic failure, unspecified	0.009	0.991	0.000
K70.0 Alcoholic fatty liver	0.009	0.991	0.000
D37.6 Liver, gallbladder and bile ducts	0.009	0.991	0.000
D43.9 Central nervous system, unspecified	0.009	0.991	0.000
D43.7 Other parts of central nervous system	0.009	0.991	0.000
D43.4 Spinal cord	0.009	0.991	0.000
D43.3 Cranial nerves	0.009	0.991	0.000
K70.1 Alcoholic hepatitis	0.009	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.009	0.991	0.000
D39.9 Female genital organ, unspecified	0.008	0.991	0.000
D39.7 Other female genital organs	0.008	0.991	0.000
D39.2 Placenta	0.008	0.991	0.000
D39.0 Uterus	0.008	0.991	0.000
D43.0 Brain, supratentorial	0.008	0.991	0.000
Y54.5 Other diuretics	0.008	0.991	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.991	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.008	0.991	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.008	0.991	0.000
Y57.8 Other drugs and medicaments	0.008	0.992	0.000
Y57.6 Other diagnostic agents	0.008	0.992	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.008	0.992	0.000
D46.1 Refractory anaemia with sideroblasts	0.008	0.992	0.000
D40.1 Testis	0.008	0.992	0.000
D44.4 Craniopharyngeal duct	0.008	0.992	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.008	0.992	0.000
D44.0 Thyroid gland	0.008	0.992	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
D44.9 Endocrine gland, unspecified	0.008	0.992	0.000
D44.8 Pluriglandular involvement	0.008	0.992	0.000
D44.7 Aortic body and other paraganglia	0.008	0.992	0.000
D44.5 Pineal gland	0.008	0.992	0.000
D44.2 Parathyroid gland	0.008	0.992	0.000
D46.2 Refractory anaemia with excess of blasts	0.008	0.992	0.000
Y54.3 Benzothiadiazine derivatives	0.008	0.992	0.000
D38.1 Trachea, bronchus and lung	0.008	0.992	0.000
Y59 Other and unspecified vaccines and biological substances	0.008	0.992	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.008	0.992	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Y57.7 Vitamins, not elsewhere classified	0.008	0.992	0.000
Y57.4 Pharmaceutical excipients	0.008	0.992	0.000
Y57.3 Alcohol deterrents	0.008	0.992	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.008	0.992	0.000
Y57.1 Lipotropic drugs	0.008	0.992	0.000
Y57.0 Appetite depressants [anorectics]	0.008	0.992	0.000
K74.6 Other and unspecified cirrhosis of liver	0.008	0.992	0.000
D46.7 Other myelodysplastic syndromes	0.008	0.992	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.008	0.992	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.008	0.992	0.000
D46.4 Refractory anaemia, unspecified	0.008	0.992	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.008	0.992	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.008	0.992	0.000
D40.9 Male genital organ, unspecified	0.008	0.992	0.000
D40.7 Other male genital organs	0.008	0.992	0.000
Y42.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
Y42.4 Oral contraceptives	0.008	0.992	0.000
Y42.2 Antithyroid drugs	0.008	0.992	0.000
Y57.9 Drug or medicament, unspecified	0.008	0.992	0.000
Y42.1 Thyroid hormones and substitutes	0.008	0.992	0.000
Y58 Bacterial vaccines	0.008	0.992	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.008	0.992	0.000
D44.3 Pituitary gland	0.008	0.992	0.000
Y45.4 Antirheumatics	0.008	0.992	0.000
D38.6 Respiratory organ, unspecified	0.007	0.992	0.000
D38.5 Other respiratory organs	0.007	0.992	0.000
D38.4 Thymus	0.007	0.992	0.000
D38.3 Mediastinum	0.007	0.992	0.000
D38.2 Pleura	0.007	0.992	0.000
Y52 Agents primarily affecting the cardiovascular system	0.008	0.992	0.000
D42.9 Meninges, unspecified	0.007	0.992	0.000
D42.1 Spinal meninges	0.007	0.992	0.000
D42.0 Cerebral meninges	0.007	0.992	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.992	0.007
Y48 Anaesthetics and therapeutic gases	0.008	0.992	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.008	0.992	0.000
D40.0 Prostate	0.007	0.992	0.000
D44.1 Adrenal gland	0.007	0.993	0.000
D48.1 Connective and other soft tissue	0.007	0.993	0.000
Y54.9 Mineral salts, not elsewhere classified	0.007	0.993	0.000
Y54.7 Agents affecting calcification	0.007	0.993	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.007	0.993	0.000
Y54.0 Mineralocorticoids	0.007	0.993	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.007	0.993	0.000
Y45.5 4-Aminophenol derivatives	0.007	0.993	0.000
D38.0 Larynx	0.007	0.993	0.000
K74.4 Secondary biliary cirrhosis	0.007	0.993	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.007	0.993	0.000
K74.1 Hepatic sclerosis	0.007	0.993	0.000
Y54.8 Agents affecting uric acid metabolism	0.007	0.993	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.007	0.993	0.000
Y41.1 Antimycobacterial drugs	0.007	0.993	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.007	0.993	0.000
Y41.0 Sulphonamides	0.007	0.993	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
H53.2 Diplopia	0.007	0.993	0.000
Y41.5 Antiviral drugs	0.007	0.993	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.007	0.993	0.000
K70.4 Alcoholic hepatic failure	0.007	0.993	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
Y54.4 Loop [high-ceiling] diuretics	0.007	0.993	0.000
Y47.1 Benzodiazepines	0.006	0.993	0.000
S42.20 Fracture of upper end of humerus (closed)	0.006	0.994	0.000
Y40 Systemic antibiotics	0.006	0.994	0.000
K74.0 Hepatic fibrosis	0.006	0.994	0.000
M47.2 Other spondylosis with radiculopathy	0.006	0.994	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
Y41.4 Anthelminthics	0.006	0.994	0.000
Y41.3 Other antiprotozoal drugs	0.006	0.994	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.006	0.994	0.000
Y44 Agents primarily affecting blood constituents	0.006	0.994	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.994	0.006
D37.7 Other digestive organs	0.006	0.994	0.000
D48.4 Peritoneum	0.006	0.994	0.000
D48.3 Retroperitoneum	0.006	0.994	0.000
Y52.7 Peripheral vasodilators	0.006	0.994	0.000
Y52.1 Calcium-channel blockers	0.006	0.994	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.006	0.994	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.006	0.994	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.006	0.994	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.006	0.994	0.000
Y47.4 Bromine compounds	0.006	0.994	0.000
Y47.3 Paraldehyde	0.006	0.994	0.000
Y47.2 Chloral derivatives	0.006	0.994	0.000
Y47.0 Barbiturates, not elsewhere classified	0.006	0.994	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y53.7 Emetics	0.006	0.994	0.000
Y53.6 Antidiarrhoeal drugs	0.006	0.994	0.000
Y53.5 Digestants	0.006	0.994	0.000
Y53.3 Saline and osmotic laxatives	0.006	0.994	0.000
Y53.2 Stimulant laxatives	0.006	0.994	0.000
Y53.0 Histamine H2-receptor antagonists	0.006	0.994	0.000
Y59.3 Immunoglobulin	0.006	0.994	0.000
Y49.5 Other antipsychotics and neuroleptics	0.006	0.994	0.000
Y49.2 Other and unspecified antidepressants	0.006	0.994	0.000
Y59.9 Vaccine or biological substance, unspecified	0.006	0.994	0.000
Y59.8 Other specified vaccines and biological substances	0.006	0.994	0.000
Y59.2 Protozoal vaccines	0.006	0.994	0.000
Y59.1 Rickettsial vaccines	0.006	0.994	0.000
Y59.0 Viral vaccines	0.006	0.994	0.000
Y49.9 Psychotropic drug, unspecified	0.006	0.994	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
Y49.7 Psychostimulants with abuse potential	0.006	0.994	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.006	0.994	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
K74.3 Primary biliary cirrhosis	0.006	0.994	0.000
Y48.3 Local anaesthetics	0.006	0.994	0.000
Y50.9 Central nervous system stimulant, unspecified	0.006	0.994	0.000
Y50.8 Other central nervous system stimulants	0.006	0.994	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.006	0.994	0.000
Y50.1 Opioid receptor antagonists	0.006	0.994	0.000
Y50.0 Analeptics	0.006	0.994	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
Y55.5 Anticommon cold drugs	0.006	0.994	0.000
Y55.4 Expectorants	0.006	0.994	0.000
Y55.3 Antitussives	0.006	0.994	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
Y55.0 Oxytocic drugs	0.006	0.994	0.000
Y58.9 Other and unspecified bacterial vaccines	0.006	0.994	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.006	0.994	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.006	0.994	0.000
Y58.5 Diphtheria vaccine	0.006	0.994	0.000
Y58.4 Tetanus vaccine	0.006	0.994	0.000
Y58.3 Plague vaccine	0.006	0.994	0.000
Y58.2 Cholera vaccine	0.006	0.994	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.006	0.994	0.000
Y58.0 BCG vaccine	0.006	0.994	0.000
Y43.4 Immunosuppressive agents	0.006	0.994	0.000
Y48.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.994	0.006
K67.3 Tuberculous peritonitis	0.000	0.994	0.006
K67.2 Syphilitic peritonitis	0.000	0.994	0.006
K67.1 Gonococcal peritonitis	0.000	0.994	0.006
K67.0 Chlamydial peritonitis	0.000	0.994	0.006
Y48.5 Therapeutic gases	0.006	0.994	0.000
Y48.1 Parenteral anaesthetics	0.006	0.994	0.000
Y48.0 Inhaled anaesthetics	0.006	0.994	0.000
Y56.9 Topical agent, unspecified	0.006	0.994	0.000
Y56.8 Other topical agents	0.006	0.994	0.000
Y56.7 Dental drugs, topically applied	0.006	0.994	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
Y56.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
Y56.3 Emollients, demulcents and protectants	0.006	0.994	0.000
Y56.2 Local astringents and local detergents	0.006	0.994	0.000
Y56.1 Antipruritics	0.006	0.994	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.006	0.994	0.000
H54.0 Blindness, both eyes	0.006	0.994	0.000
K65.8 Other peritonitis	0.000	0.994	0.005
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
K01 Embedded and impacted teeth	0.006	0.994	0.000
Y53.4 Other laxatives	0.005	0.994	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.994	0.006
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.994	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.994	0.000
D48.0 Bone and articular cartilage	0.005	0.994	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.006	0.994	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.994	0.006
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
S42.40 Fracture of lower end of humerus (closed)	0.005	0.995	0.000
Y48.4 Anaesthetic, unspecified	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.995	0.005
M77.9 Enthesopathy, unspecified	0.005	0.995	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.995	0.005
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
T93 Sequelae of injuries of lower limb	0.000	0.995	0.005
D48.6 Breast	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.005	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.995	0.000
Y43.2 Antineoplastic natural products	0.005	0.995	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
Y51.0 Anticholinesterase agents	0.005	0.995	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.995	0.005
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
S42.2 Fracture of upper end of humerus	0.005	0.995	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations