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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7968960
log Bayes Factor = 18.337
Chromosome 12   position 111,426,615  (GRCh37) Explore rs7968960 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.999 0.001 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.996 0.004 0.000
I10 Essential (primary) hypertension
0.996 0.004 0.000
E03 Other hypothyroidism
0.993 0.007 0.000
I10-I15 Hypertensive diseases
0.988 0.012 0.000
M06.9 Rheumatoid arthritis, unspecified
0.987 0.013 0.000
Chapter IX Diseases of the circulatory system
0.985 0.015 0.000
M06 Other rheumatoid arthritis
0.982 0.018 0.000
E00-E07 Disorders of thyroid gland
0.981 0.019 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.979 0.021 0.000
I25.5 Ischaemic cardiomyopathy
0.974 0.026 0.000
M06.0 Seronegative rheumatoid arthritis
0.968 0.032 0.000
E06 Thyroiditis
0.968 0.032 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.961 0.039 0.000
I27 Other pulmonary heart diseases
0.960 0.040 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.958 0.042 0.000
E06.3 Autoimmune thyroiditis
0.958 0.042 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.956 0.044 0.000
Z95.1 Presence of aortocoronary bypass graft
0.952 0.048 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.951 0.049 0.000
E05.9 Thyrotoxicosis, unspecified
0.944 0.056 0.000
Z95.2 Presence of prosthetic heart valve
0.942 0.058 0.000
I27.2 Other secondary pulmonary hypertension
0.941 0.059 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.938 0.062 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.933 0.067 0.000
Z95.4 Presence of other heart-valve replacement
0.930 0.070 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.930 0.070 0.000
M05-M14 Inflammatory polyarthropathies
0.930 0.070 0.000
I22 Subsequent myocardial infarction
0.925 0.075 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.914 0.086 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.913 0.087 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.906 0.094 0.000
M05 Seropositive rheumatoid arthritis
0.905 0.095 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.905 0.095 0.000
I23 Certain current complications following acute myocardial infarction
0.903 0.097 0.000
M07 Psoriatic and enteropathic arthropathies
0.901 0.099 0.000
I26 Pulmonary embolism
0.894 0.106 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.887 0.113 0.000
M07.3 Other psoriatic arthropathies
0.880 0.120 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.875 0.125 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.862 0.138 0.000
E03.8 Other specified hypothyroidism
0.857 0.143 0.000
I27.0 Primary pulmonary hypertension
0.854 0.146 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.839 0.161 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.831 0.169 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.830 0.170 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.828 0.172 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.826 0.174 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.823 0.177 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.818 0.182 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.816 0.184 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.808 0.192 0.000
I15 Secondary hypertension
0.805 0.195 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.804 0.196 0.000
I25.2 Old myocardial infarction
0.801 0.199 0.000
I28 Other diseases of pulmonary vessels
0.789 0.211 0.000
E05.8 Other thyrotoxicosis
0.787 0.213 0.000
I23.8 Other current complications following acute myocardial infarction
0.783 0.217 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.766 0.233 0.000
I25.6 Silent myocardial ischaemia
0.766 0.234 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.766 0.234 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.764 0.236 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.763 0.237 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.759 0.241 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.757 0.243 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.755 0.245 0.000
M06.4 Inflammatory polyarthropathy
0.746 0.254 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.742 0.258 0.000
M08 Juvenile arthritis
0.738 0.262 0.000
E03.1 Congenital hypothyroidism without goitre
0.730 0.270 0.000
E06.9 Thyroiditis, unspecified
0.726 0.274 0.000
I25.3 Aneurysm of heart
0.720 0.280 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.714 0.286 0.000
E03.5 Myxoedema coma
0.712 0.288 0.000
E03.4 Atrophy of thyroid (acquired)
0.712 0.288 0.000
E03.3 Postinfectious hypothyroidism
0.712 0.288 0.000
I13 Hypertensive heart and renal disease
0.709 0.291 0.000
M06.2 Rheumatoid bursitis
0.704 0.296 0.000
M06.1 Adult-onset Still's disease
0.704 0.296 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.703 0.297 0.000
E00 Congenital iodine-deficiency syndrome
0.703 0.297 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.298 0.000
I11 Hypertensive heart disease
0.696 0.303 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.696 0.304 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.694 0.305 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.694 0.306 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.694 0.306 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.694 0.306 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.694 0.306 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.694 0.306 0.000
E06.4 Drug-induced thyroiditis
0.694 0.306 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.694 0.306 0.000
E06.0 Acute thyroiditis
0.694 0.306 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.693 0.307 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.690 0.310 0.000
I27.1 Kyphoscoliotic heart disease
0.688 0.312 0.000
E06.1 Subacute thyroiditis
0.687 0.313 0.000
E05.5 Thyroid crisis or storm
0.687 0.313 0.000
E05.4 Thyrotoxicosis factitia
0.687 0.313 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.687 0.313 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.684 0.315 0.000
E06.5 Other chronic thyroiditis
0.683 0.316 0.000
I22.8 Subsequent myocardial infarction of other sites
0.680 0.320 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.676 0.323 0.000
I27.8 Other specified pulmonary heart diseases
0.674 0.326 0.000
M05.1 Rheumatoid lung disease
0.672 0.328 0.000
M12 Other specific arthropathies
0.670 0.329 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.670 0.330 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.668 0.332 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.667 0.333 0.000
M05.2 Rheumatoid vasculitis
0.662 0.338 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.662 0.338 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.661 0.339 0.000
I25.4 Coronary artery aneurysm
0.658 0.342 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.654 0.346 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.653 0.347 0.000
I28.8 Other specified diseases of pulmonary vessels
0.653 0.347 0.000
I15.1 Hypertension secondary to other renal disorders
0.652 0.348 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.649 0.351 0.000
M05.0 Felty's syndrome
0.649 0.351 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.648 0.352 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.648 0.352 0.000
M07.6 Other enteropathic arthropathies
0.646 0.354 0.000
M07.5 Arthropathy in ulcerative colitis
0.646 0.354 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.646 0.354 0.000
M07.2 Psoriatic spondylitis
0.646 0.354 0.000
M07.1 Arthritis mutilans
0.646 0.354 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.646 0.354 0.000
I21.9 Acute myocardial infarction, unspecified
0.643 0.357 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.639 0.361 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.636 0.364 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.636 0.364 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.636 0.364 0.000
M07.38 Other psoriatic arthropathies (Other)
0.631 0.369 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.631 0.369 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.631 0.369 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.631 0.369 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.628 0.372 0.000
Z95.3 Presence of xenogenic heart valve
0.626 0.374 0.000
M05.8 Other seropositive rheumatoid arthritis
0.610 0.390 0.000
I21.4 Acute subendocardial myocardial infarction
0.608 0.392 0.000
I15.0 Renovascular hypertension
0.596 0.404 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.596 0.404 0.000
I15.9 Seconday hypertension, unspecified
0.589 0.411 0.000
M08.9 Juvenile arthritis, unspecified
0.587 0.413 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.586 0.414 0.000
I15.8 Other secondary hypertension
0.577 0.423 0.000
I15.2 Hypertension secondary to endocrine disorders
0.577 0.423 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.566 0.434 0.000
I28.1 Aneurysm of pulmonary artery
0.566 0.434 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.566 0.434 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.566 0.434 0.000
M14 Arthropathies in other diseases classified elsewhere
0.554 0.446 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.551 0.448 0.000
M08.0 Juvenile rheumatoid arthritis
0.548 0.451 0.000
M06.3 Rheumatoid nodule
0.544 0.456 0.000
M11 Other crystal arthropathies
0.544 0.456 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.543 0.457 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.535 0.465 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.535 0.465 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.535 0.465 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.535 0.465 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.535 0.465 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.535 0.465 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.535 0.465 0.000
M08.8 Other juvenile arthritis
0.529 0.471 0.000
M08.4 Pauciarticular juvenile arthritis
0.529 0.471 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.529 0.471 0.000
M08.2 Juvenile arthritis with systemic onset
0.529 0.471 0.000
M08.1 Juvenile ankylosing spondylitis
0.529 0.471 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.529 0.471 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.527 0.473 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.519 0.481 0.000
M12.2 Villonodular synovitis (pigmented)
0.509 0.491 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.508 0.492 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.508 0.492 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.508 0.492 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.508 0.492 0.000
M10 Gout
0.505 0.495 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.505 0.495 0.000
M06.18 Adult-onset Still's disease (Other)
0.505 0.495 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.505 0.495 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.505 0.495 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.505 0.495 0.000
M06.14 Adult-onset Still's disease (Hand)
0.505 0.495 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.505 0.495 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.505 0.495 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.505 0.495 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.505 0.495 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.505 0.495 0.000
M06.28 Rheumatoid bursitis (Other)
0.505 0.495 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.505 0.495 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.505 0.495 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.505 0.495 0.000
M06.24 Rheumatoid bursitis (Hand)
0.505 0.495 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.505 0.495 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.505 0.495 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.505 0.495 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.505 0.495 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.505 0.495 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.505 0.495 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.504 0.496 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.504 0.496 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.504 0.496 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.504 0.496 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.504 0.496 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.504 0.496 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.504 0.496 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.504 0.496 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.503 0.497 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.503 0.497 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.503 0.497 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.503 0.497 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.503 0.497 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.503 0.497 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.503 0.497 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.503 0.497 0.000
M12.5 Traumatic arthropathy
0.502 0.498 0.000
I02 Rheumatic chorea
0.499 0.501 0.000
I01 Rheumatic fever with heart involvement
0.499 0.501 0.000
I00 Rheumatic fever without mention of heart involvement
0.489 0.511 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.488 0.512 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.484 0.516 0.000
M05.18 Rheumatoid lung disease (Other)
0.482 0.518 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.482 0.518 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.482 0.518 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.482 0.518 0.000
M05.14 Rheumatoid lung disease (Hand)
0.482 0.518 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.482 0.518 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.482 0.518 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.482 0.518 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.482 0.518 0.000
M12.4 Intermittent hydrarthrosis
0.481 0.519 0.000
M12.1 Kaschin-Beck disease
0.481 0.519 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.481 0.519 0.000
I27.9 Pulmonary heart disease, unspecified
0.480 0.520 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.478 0.522 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.478 0.522 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.478 0.522 0.000
M09.0 Juvenile arthritis in psoriasis
0.478 0.522 0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)
0.478 0.522 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.477 0.522 0.000
M05.28 Rheumatoid vasculitis (Other)
0.475 0.525 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.475 0.525 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.475 0.525 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.475 0.525 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.475 0.525 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.475 0.525 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.475 0.525 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.475 0.525 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.475 0.525 0.000
M05.09 Felty's syndrome (Site unspecified)
0.465 0.535 0.000
M05.08 Felty's syndrome (Other)
0.465 0.535 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.465 0.535 0.000
M05.06 Felty's syndrome (Lower leg)
0.465 0.535 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.465 0.535 0.000
M05.04 Felty's syndrome (Hand)
0.465 0.535 0.000
M05.03 Felty's syndrome (Forearm)
0.465 0.535 0.000
M05.02 Felty's syndrome (Upper arm)
0.465 0.535 0.000
M05.01 Felty's syndrome (Shoulder region)
0.465 0.535 0.000
M05.00 Felty's syndrome (Multiple sites)
0.465 0.535 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.465 0.535 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.465 0.535 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.465 0.535 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.465 0.535 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.465 0.535 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.465 0.535 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.465 0.535 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.465 0.535 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.465 0.535 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.465 0.535 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.463 0.537 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.463 0.537 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.463 0.537 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.463 0.537 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.463 0.537 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.463 0.537 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.463 0.537 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.463 0.537 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.463 0.537 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.463 0.537 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.463 0.537 0.000
M07.18 Arthritis mutilans (Other)
0.463 0.537 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.463 0.537 0.000
M07.16 Arthritis mutilans (Lower leg)
0.463 0.537 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.463 0.537 0.000
M07.14 Arthritis mutilans (Hand)
0.463 0.537 0.000
M07.13 Arthritis mutilans (Forearm)
0.463 0.537 0.000
M07.12 Arthritis mutilans (Upper arm)
0.463 0.537 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.463 0.537 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.463 0.537 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.463 0.537 0.000
M07.28 Psoriatic spondylitis (Other)
0.463 0.537 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.463 0.537 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.463 0.537 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.463 0.537 0.000
M07.24 Psoriatic spondylitis (Hand)
0.463 0.537 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.463 0.537 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.463 0.537 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.463 0.537 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.463 0.537 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.463 0.537 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.463 0.537 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.463 0.537 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.463 0.537 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.463 0.537 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.463 0.537 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.463 0.537 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.463 0.537 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.463 0.537 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.463 0.537 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.463 0.537 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.463 0.537 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.463 0.537 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.463 0.537 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.463 0.537 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.463 0.537 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.463 0.537 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.463 0.537 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.463 0.537 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.463 0.537 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.463 0.537 0.000
M07.68 Other enteropathic arthropathies (Other)
0.463 0.537 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.463 0.537 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.463 0.537 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.463 0.537 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.463 0.537 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.463 0.537 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.463 0.537 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.463 0.537 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.463 0.537 0.000
E07 Other disorders of thyroid
0.457 0.542 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.450 0.549 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.448 0.552 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.437 0.563 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.437 0.563 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.437 0.563 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.437 0.563 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.437 0.563 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.437 0.563 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.437 0.563 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.437 0.563 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.437 0.563 0.000
M12.3 Palindromic rheumatism
0.429 0.571 0.000
M08.98 Juvenile arthritis, unspecified (Other)
0.421 0.579 0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)
0.421 0.579 0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)
0.421 0.579 0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)
0.421 0.579 0.000
M08.94 Juvenile arthritis, unspecified (Hand)
0.421 0.579 0.000
M08.93 Juvenile arthritis, unspecified (Forearm)
0.421 0.579 0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)
0.421 0.579 0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)
0.421 0.579 0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)
0.421 0.579 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.412 0.587 0.000
I05-I09 Chronic rheumatic heart diseases
0.407 0.593 0.000
I12 Hypertensive renal disease
0.406 0.594 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.398 0.602 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.397 0.602 0.000
M14.4 Arthropathy in amyloidosis
0.397 0.602 0.000
M14.3 Lipoid dermatoarthritis
0.397 0.602 0.000
M14.2 Diabetic arthropathy
0.397 0.602 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.397 0.602 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.397 0.602 0.000
M10.0 Idiopathic gout
0.396 0.604 0.000
S72 Fracture of femur
0.395 0.605 0.000
S72.00 Fracture of neck of femur (closed)
0.395 0.605 0.000
S72.0 Fracture of neck of femur
0.394 0.606 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.393 0.607 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.393 0.607 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.393 0.607 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.393 0.607 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.393 0.607 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.393 0.607 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.393 0.607 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.393 0.607 0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.393 0.607 0.000
M11.9 Crystal arthropathy, unspecified
0.392 0.608 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.391 0.609 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.390 0.610 0.000
M06.38 Rheumatoid nodule (Other)
0.390 0.610 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.390 0.610 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.390 0.610 0.000
M06.33 Rheumatoid nodule (Forearm)
0.390 0.610 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.390 0.610 0.000
M11.1 Familial chondrocalcinosis
0.390 0.610 0.000
M11.0 Hydroxyapatite deposition disease
0.390 0.610 0.000
S72.1 Pertrochanteric fracture
0.389 0.611 0.000
M06.34 Rheumatoid nodule (Hand)
0.385 0.615 0.000
S72.10 Pertrochanteric fracture (closed)
0.385 0.615 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.382 0.618 0.000
M12.57 Traumatic arthropathy (Ankle and foot)
0.381 0.619 0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.379 0.620 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.379 0.620 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.379 0.620 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.379 0.620 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.379 0.620 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.379 0.620 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.379 0.620 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.379 0.620 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.379 0.620 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.379 0.620 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.379 0.620 0.000
M08.28 Juvenile arthritis with systemic onset (Other)
0.379 0.620 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.379 0.620 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.379 0.620 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.379 0.620 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.379 0.620 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.379 0.620 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.379 0.620 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.379 0.620 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.379 0.620 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.379 0.620 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.379 0.620 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.379 0.620 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.379 0.620 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.379 0.620 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.379 0.620 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.379 0.620 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.379 0.620 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.379 0.620 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.379 0.620 0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.379 0.620 0.000
M08.48 Pauciarticular juvenile arthritis (Other)
0.379 0.620 0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.379 0.620 0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.379 0.620 0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.379 0.620 0.000
M08.44 Pauciarticular juvenile arthritis (Hand)
0.379 0.620 0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.379 0.620 0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.379 0.620 0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)
0.379 0.620 0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)
0.379 0.620 0.000
M08.89 Other juvenile arthritis (Site unspecified)
0.379 0.620 0.000
M08.88 Other juvenile arthritis (Other)
0.379 0.620 0.000
M08.87 Other juvenile arthritis (Ankle and foot)
0.379 0.620 0.000
M08.86 Other juvenile arthritis (Lower leg)
0.379 0.620 0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)
0.379 0.620 0.000
M08.84 Other juvenile arthritis (Hand)
0.379 0.620 0.000
M08.83 Other juvenile arthritis (Forearm)
0.379 0.620 0.000
M08.82 Other juvenile arthritis (Upper arm)
0.379 0.620 0.000
M08.81 Other juvenile arthritis (Shoulder region)
0.379 0.620 0.000
M08.80 Other juvenile arthritis (Multiple sites)
0.379 0.620 0.000
M11.8 Other specified crystal arthropathies
0.377 0.623 0.000
S72.3 Fracture of shaft of femur
0.371 0.629 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.367 0.633 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.365 0.635 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.365 0.635 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.365 0.635 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.365 0.635 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.365 0.635 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.365 0.635 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.365 0.635 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.365 0.635 0.000
M10.4 Other secondary gout
0.362 0.637 0.000
M10.3 Gout due to impairment of renal function
0.362 0.637 0.000
M10.2 Drug-induced gout
0.362 0.637 0.000
M10.1 Lead-induced gout
0.362 0.637 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.362 0.638 0.000
M41.9 Scoliosis, unspecified
0.361 0.639 0.000
M40-M43 Deforming dorsopathies
0.361 0.639 0.000
M12.59 Traumatic arthropathy (Site unspecified)
0.360 0.640 0.000
M12.58 Traumatic arthropathy (Other)
0.360 0.640 0.000
M12.56 Traumatic arthropathy (Lower leg)
0.360 0.640 0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.360 0.640 0.000
M12.54 Traumatic arthropathy (Hand)
0.360 0.640 0.000
M12.53 Traumatic arthropathy (Forearm)
0.360 0.640 0.000
M12.52 Traumatic arthropathy (Upper arm)
0.360 0.640 0.000
M12.51 Traumatic arthropathy (Shoulder region)
0.360 0.640 0.000
M12.50 Traumatic arthropathy (Multiple sites)
0.360 0.640 0.000
M41 Scoliosis
0.359 0.641 0.000
S72.4 Fracture of lower end of femur
0.358 0.642 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.358 0.642 0.000
I01.8 Other acute rheumatic heart disease
0.358 0.642 0.000
I01.2 Acute rheumatic myocarditis
0.358 0.642 0.000
I01.1 Acute rheumatic endocarditis
0.358 0.642 0.000
I01.0 Acute rheumatic pericarditis
0.358 0.642 0.000
I02.9 Rheumatic chorea without heart involvement
0.358 0.642 0.000
I02.0 Rheumatic chorea with heart involvement
0.358 0.642 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.356 0.644 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.356 0.644 0.000
S72.30 Fracture of shaft of femur (closed)
0.351 0.649 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.350 0.650 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.348 0.652 0.000
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)
0.345 0.655 0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)
0.345 0.655 0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)
0.345 0.655 0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)
0.345 0.655 0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)
0.345 0.655 0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)
0.345 0.655 0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)
0.345 0.655 0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)
0.345 0.655 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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