TreeWAS – Variant ID: rs8005745

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O70.1 Second degree perineal laceration during delivery	0.038	0.962	0.000
K22.2 Oesophageal obstruction	0.000	0.973	0.027
O70 Perineal laceration during delivery	0.024	0.976	0.000
O70.2 Third degree perineal laceration during delivery	0.019	0.981	0.000
O70.3 Fourth degree perineal laceration during delivery	0.019	0.981	0.000
O70.9 Perineal laceration during delivery, unspecified	0.018	0.982	0.000
O60-O75 Complications of labour and delivery	0.016	0.984	0.000
O63 Long labour	0.014	0.986	0.000
O63.1 Prolonged second stage (of labour)	0.014	0.986	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.013	0.987	0.000
O66 Other obstructed labour	0.013	0.987	0.000
S72.00 Fracture of neck of femur (closed)	0.013	0.987	0.000
O62 Abnormalities of forces of labour	0.013	0.987	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.013	0.987	0.000
O74 Complications of anaesthesia during labour and delivery	0.012	0.988	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.988	0.012
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.012	0.988	0.000
O62.3 Precipitate labour	0.012	0.988	0.000
O16 Unspecified maternal hypertension	0.012	0.988	0.000
D48.6 Breast	0.000	0.988	0.012
O60 Preterm delivery	0.011	0.989	0.000
O63.9 Long labour, unspecified	0.011	0.989	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.011	0.989	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.011	0.989	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.011	0.989	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.011	0.989	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.011	0.989	0.000
K61.0 Anal abscess	0.000	0.989	0.011
Chapter XV Pregnancy, childbirth and the puerperium	0.011	0.989	0.000
D48.5 Skin	0.000	0.989	0.011
O73 Retained placenta and membranes, without haemorrhage	0.011	0.989	0.000
O61 Failed induction of labour	0.011	0.989	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.010	0.989	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.989	0.011
O75 Other complications of labour and delivery, not elsewhere classified	0.010	0.990	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O62.9 Abnormality of forces of labour, unspecified	0.010	0.990	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.010	0.990	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.010	0.990	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.990	0.010
D37.0 Lip, oral cavity and pharynx	0.000	0.990	0.010
O66.2 Obstructed labour due to unusually large foetus	0.010	0.990	0.000
O62.8 Other abnormalities of forces of labour	0.010	0.990	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.990	0.010
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.990	0.010
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.010	0.990	0.000
O66.8 Other specified obstructed labour	0.010	0.990	0.000
O64.2 Obstructed labour due to face presentation	0.009	0.990	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.009	0.990	0.000
O66.1 Obstructed labour due to locked twins	0.009	0.990	0.000
O62.2 Other uterine inertia	0.009	0.990	0.000
O85-O92 Complications predominantly related to the puerperium	0.009	0.991	0.000
O64.3 Obstructed labour due to brow presentation	0.009	0.991	0.000
O66.9 Obstructed labour, unspecified	0.009	0.991	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.009	0.991	0.000
O64.5 Obstructed labour due to compound presentation	0.009	0.991	0.000
O64.4 Obstructed labour due to shoulder presentation	0.009	0.991	0.000
D48.0 Bone and articular cartilage	0.000	0.991	0.009
O62.1 Secondary uterine inertia	0.009	0.991	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.009	0.991	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.009	0.991	0.000
D48.1 Connective and other soft tissue	0.000	0.991	0.009
D48.4 Peritoneum	0.000	0.991	0.009
D48.3 Retroperitoneum	0.000	0.991	0.009
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.009	0.991	0.000
D45 Polycythaemia vera	0.000	0.991	0.009
O80-O84 Delivery	0.009	0.991	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.009	0.991	0.000
O75.0 Maternal distress during labour and delivery	0.009	0.991	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.991	0.009
D46 Myelodysplastic syndromes	0.000	0.991	0.009
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.009	0.991	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.009	0.991	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.009	0.991	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.009	0.991	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.009	0.991	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.009	0.991	0.000
D48.7 Other specified sites	0.000	0.991	0.009
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.009	0.991	0.000
O66.4 Failed trial of labour, unspecified	0.009	0.991	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.991	0.008
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.008	0.991	0.000
O20 Haemorrhage in early pregnancy	0.009	0.991	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.991	0.009
O60.3 Preterm delivery without spontaneous labour	0.008	0.992	0.000
O60.2 Preterm spontaneous labour with term delivery	0.008	0.992	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.008	0.992	0.000
O60.0 Preterm labour without delivery	0.008	0.992	0.000
O61.9 Failed induction of labour, unspecified	0.008	0.992	0.000
D37.1 Stomach	0.000	0.992	0.008
O75.3 Other infection during labour	0.008	0.992	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.008	0.992	0.000
O20.0 Threatened abortion	0.008	0.992	0.000
O67.8 Other intrapartum haemorrhage	0.008	0.992	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.008	0.992	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.008	0.992	0.000
O87 Venous complications in the puerperium	0.008	0.992	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.992	0.008
D47.1 Chronic myeloproliferative disease	0.000	0.992	0.008
O85 Puerperal sepsis	0.008	0.992	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.992	0.008
O61.8 Other failed induction of labour	0.008	0.992	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.008	0.992	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.008	0.992	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.008	0.992	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.008	0.992	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.008	0.992	0.000
O65.0 Obstructed labour due to deformed pelvis	0.008	0.992	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.008	0.992	0.000
O61.1 Failed instrumental induction of labour	0.008	0.992	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.992	0.008
O81 Single delivery by forceps and vacuum extractor	0.008	0.992	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.008	0.992	0.000
O75.9 Complication of labour and delivery, unspecified	0.008	0.992	0.000
O75.4 Other complications of obstetric surgery and procedures	0.008	0.992	0.000
O75.1 Shock during or following labour and delivery	0.008	0.992	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.008	0.992	0.000
D37.5 Rectum	0.000	0.992	0.008
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.992	0.007
O28 Abnormal findings on antenatal screening of mother	0.008	0.992	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.007	0.992	0.000
O15 Eclampsia	0.007	0.992	0.000
D37.9 Digestive organ, unspecified	0.000	0.993	0.007
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.993	0.007
D47.4 Osteomyelofibrosis	0.000	0.993	0.007
O89 Complications of anaesthesia during the puerperium	0.007	0.993	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.993	0.007
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.007	0.993	0.000
O64.1 Obstructed labour due to breech presentation	0.007	0.993	0.000
O71 Other obstetric trauma	0.007	0.993	0.001
D37.3 Appendix	0.000	0.993	0.007
D46.7 Other myelodysplastic syndromes	0.000	0.993	0.007
O91 Infections of breast associated with childbirth	0.007	0.993	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.007	0.993	0.000
O72 Postpartum haemorrhage	0.007	0.993	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.993	0.007
O48 Prolonged pregnancy	0.007	0.993	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O20.8 Other haemorrhage in early pregnancy	0.007	0.993	0.000
O81.4 Vacuum extractor delivery	0.007	0.993	0.000
O88 Obstetric embolism	0.007	0.993	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.993	0.007
O23 Infections of genito-urinary tract in pregnancy	0.007	0.993	0.000
O62.0 Primary inadequate contractions	0.007	0.993	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.007	0.993	0.000
O22 Venous complications in pregnancy	0.007	0.993	0.000
O83 Other assisted single delivery	0.007	0.993	0.000
O86 Other puerperal infections	0.007	0.993	0.000
S72.0 Fracture of neck of femur	0.007	0.993	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.007	0.993	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.007	0.993	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.993	0.007
O84 Multiple delivery	0.007	0.993	0.000
O82 Single delivery by Caesarean section	0.007	0.993	0.000
O75.8 Other specified complications of labour and delivery	0.007	0.993	0.000
O29 Complications of anaesthesia during pregnancy	0.007	0.993	0.000
O25 Malnutrition in pregnancy	0.007	0.993	0.000
O12.0 Gestational oedema	0.007	0.993	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.993	0.007
D37.2 Small intestine	0.000	0.993	0.007
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.993	0.007
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.993	0.006
D46.4 Refractory anaemia, unspecified	0.000	0.993	0.006
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.993	0.006
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.993	0.007
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.993	0.006
O61.0 Failed medical induction of labour	0.006	0.993	0.000
O87.2 Haemorrhoids in the puerperium	0.006	0.993	0.000
O90 Complications of the puerperium, not elsewhere classified	0.006	0.993	0.000
O63.0 Prolonged first stage (of labour)	0.006	0.993	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.994	0.006
D47.2 Monoclonal gammopathy	0.000	0.994	0.006
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.006	0.994	0.000
O73.0 Retained placenta, without haemorrhage	0.006	0.994	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.994	0.006
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.994	0.006
O87.0 Superficial thrombophlebitis in the puerperium	0.006	0.994	0.000
O87.8 Other venous complications in the puerperium	0.006	0.994	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.994	0.006
D44.4 Craniopharyngeal duct	0.000	0.994	0.006
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.006	0.994	0.000
D40.7 Other male genital organs	0.000	0.994	0.006
O20.9 Haemorrhage in early pregnancy, unspecified	0.006	0.994	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.006	0.994	0.000
D44.8 Pluriglandular involvement	0.000	0.994	0.006
D44.9 Endocrine gland, unspecified	0.000	0.994	0.006
O94-O99 Other obstetric conditions, not elsewhere classified	0.006	0.994	0.000
D37.4 Colon	0.000	0.994	0.006
O46 Antepartum haemorrhage, not elsewhere classified	0.006	0.994	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.006	0.994	0.000
D38.0 Larynx	0.000	0.994	0.006
D44.6 Carotid body	0.000	0.994	0.006
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.006	0.994	0.000
O14.0 Moderate preeclampsia	0.006	0.994	0.000
O80 Single spontaneous delivery	0.006	0.994	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.006	0.994	0.000
O81.0 Low forceps delivery	0.006	0.994	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.006	0.994	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.006	0.994	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.000	0.994	0.006
D40.0 Prostate	0.000	0.994	0.006
D44.7 Aortic body and other paraganglia	0.000	0.994	0.006
O28.0 Abnormal haematological finding on antenatal screening of mother	0.006	0.994	0.000
D40.9 Male genital organ, unspecified	0.000	0.994	0.006
D40.1 Testis	0.000	0.994	0.006
O14.9 Preeclampsia, unspecified	0.006	0.994	0.000
O21 Excessive vomiting in pregnancy	0.006	0.994	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.006	0.994	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.994	0.006
D44.5 Pineal gland	0.000	0.994	0.006
D44.2 Parathyroid gland	0.000	0.994	0.006
O12.2 Gestational oedema with proteinuria	0.006	0.994	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.006	0.994	0.000
O81.2 Mid-cavity forceps with rotation	0.006	0.994	0.000
O81.1 Mid-cavity forceps delivery	0.006	0.994	0.000
O14.2 HELLP syndrome	0.006	0.994	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.994	0.000
O91.1 Abscess of breast associated with childbirth	0.006	0.994	0.000
O87.9 Venous complication in the puerperium, unspecified	0.006	0.994	0.000
O70.0 First degree perineal laceration during delivery	0.006	0.994	0.000
D38.3 Mediastinum	0.000	0.994	0.006
D43.4 Spinal cord	0.000	0.994	0.006
O22.4 Haemorrhoids in pregnancy	0.006	0.994	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.006	0.994	0.000
O43 Placental disorders	0.006	0.994	0.000
D42.1 Spinal meninges	0.000	0.994	0.005
D42.0 Cerebral meninges	0.000	0.994	0.005
O28.8 Other abnormal findings on antenatal screening of mother	0.006	0.994	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.006	0.994	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.006	0.994	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.006	0.994	0.000
O24 Diabetes mellitus in pregnancy	0.006	0.994	0.000
O86.4 Pyrexia of unknown origin following delivery	0.006	0.994	0.000
D38.6 Respiratory organ, unspecified	0.000	0.994	0.005
D38.4 Thymus	0.000	0.994	0.005
O15.9 Eclampsia, unspecified as to time period	0.005	0.994	0.000
O15.1 Eclampsia in labour	0.005	0.994	0.000
O15.0 Eclampsia in pregnancy	0.005	0.994	0.000
D42.9 Meninges, unspecified	0.000	0.994	0.005
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.005	0.994	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.005	0.994	0.000
O89.6 Failed or difficult intubation during the puerperium	0.005	0.994	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.005	0.994	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.005	0.994	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.005	0.994	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.005	0.994	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.005	0.994	0.000
D38.2 Pleura	0.000	0.994	0.005
O71.9 Obstetric trauma, unspecified	0.005	0.994	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.994	0.005
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.994	0.001
R16.1 Splenomegaly, not elsewhere classified	0.000	0.994	0.006
D44.0 Thyroid gland	0.000	0.994	0.005
O90.9 Complication of the puerperium, unspecified	0.005	0.994	0.000
E28 Ovarian dysfunction	0.000	0.994	0.006
O71.2 Postpartum inversion of uterus	0.005	0.994	0.001
O71.1 Rupture of uterus during labour	0.005	0.994	0.001
O71.0 Rupture of uterus before onset of labour	0.005	0.994	0.001
O86.1 Other infection of genital tract following delivery	0.005	0.994	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.994	0.006
O14.1 Severe preeclampsia	0.005	0.994	0.000
O91.0 Infection of nipple associated with childbirth	0.005	0.994	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.005	0.994	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.005	0.994	0.000
O69.3 Labour and delivery complicated by short cord	0.005	0.994	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.005	0.994	0.000
O47 False labour	0.005	0.994	0.000
O41 Other disorders of amniotic fluid and membranes	0.005	0.994	0.000
O71.3 Obstetric laceration of cervix	0.005	0.995	0.001
O81.3 Other and unspecified forceps delivery	0.005	0.995	0.000
D44.3 Pituitary gland	0.000	0.995	0.005
E28.3 Primary ovarian failure	0.000	0.995	0.005
O72.3 Postpartum coagulation defects	0.005	0.995	0.000
O83.1 Other assisted breech delivery	0.005	0.995	0.000
O90.1 Disruption of perineal obstetric wound	0.005	0.995	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.005	0.995	0.000
O71.5 Other obstetric injury to pelvic organs	0.005	0.995	0.001
O86.2 Urinary tract infection following delivery	0.005	0.995	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.005	0.995	0.000
O15.2 Eclampsia in the puerperium	0.005	0.995	0.000
O71.7 Obstetric haematoma of pelvis	0.005	0.995	0.001
E28.2 Polycystic ovarian syndrome	0.000	0.995	0.005
O00-O08 Pregnancy with abortive outcome	0.005	0.995	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O23.0 Infections of kidney in pregnancy	0.005	0.995	0.000
O44 Placenta praevia	0.005	0.995	0.000
D44.1 Adrenal gland	0.000	0.995	0.005
O69.0 Labour and delivery complicated by prolapse of cord	0.005	0.995	0.000
O88.8 Other obstetric embolism	0.005	0.995	0.000
O88.3 Obstetric pyaemic and septic embolism	0.005	0.995	0.000
O88.2 Obstetric blood-clot embolism	0.005	0.995	0.000
O88.1 Amniotic fluid embolism	0.005	0.995	0.000
O88.0 Obstetric air embolism	0.005	0.995	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.005	0.995	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.005	0.995	0.000
O23.2 Infections of urethra in pregnancy	0.005	0.995	0.000
O23.1 Infections of bladder in pregnancy	0.005	0.995	0.000
O46.8 Other antepartum haemorrhage	0.005	0.995	0.000
O82.1 Delivery by emergency Caesarean section	0.005	0.995	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
D38.5 Other respiratory organs	0.000	0.995	0.005
D38.1 Trachea, bronchus and lung	0.000	0.995	0.005
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O22.9 Venous complication in pregnancy, unspecified	0.005	0.995	0.000
O22.8 Other venous complications in pregnancy	0.005	0.995	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.005	0.995	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.005	0.995	0.000
O83.9 Assisted single delivery, unspecified	0.005	0.995	0.000
O83.8 Other specified assisted single delivery	0.005	0.995	0.000
O83.4 Destructive operation for delivery	0.005	0.995	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.005	0.995	0.000
O83.2 Other manipulation-assisted delivery	0.005	0.995	0.000
O83.0 Breech extraction	0.005	0.995	0.000
S72.01 Fracture of neck of femur (open)	0.005	0.995	0.000
O86.3 Other genito-urinary tract infections following delivery	0.005	0.995	0.000
O92.7 Other and unspecified disorders of lactation	0.005	0.995	0.000
O92.6 Galactorrhoea	0.005	0.995	0.000
O92.5 Suppressed lactation	0.005	0.995	0.000
O92.4 Hypogalactia	0.005	0.995	0.000
O92.3 Agalactia	0.005	0.995	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.005	0.995	0.000
O92.0 Retracted nipple associated with childbirth	0.005	0.995	0.000
O84.2 Multiple delivery, all by Caesarean section	0.005	0.995	0.000
O30 Multiple gestation	0.005	0.995	0.000
O82.9 Delivery by Caesarean section, unspecified	0.005	0.995	0.000
O82.8 Other single delivery by Caesarean section	0.005	0.995	0.000
O82.2 Delivery by Caesarean hysterectomy	0.005	0.995	0.000
O84.9 Multiple delivery, unspecified	0.005	0.995	0.000
O84.8 Other multiple delivery	0.005	0.995	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.005	0.995	0.000
O84.0 Multiple delivery, all spontaneous	0.005	0.995	0.000
O36 Maternal care for other known or suspected foetal problems	0.005	0.995	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.005	0.995	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.995	0.005
D43.9 Central nervous system, unspecified	0.000	0.995	0.005
D43.7 Other parts of central nervous system	0.000	0.995	0.005
D43.3 Cranial nerves	0.000	0.995	0.005
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.995	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.005	0.995	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.005	0.995	0.000
O29.6 Failed or difficult intubation during pregnancy	0.005	0.995	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.005	0.995	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.005	0.995	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.005	0.995	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.005	0.995	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.005	0.995	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.005	0.995	0.000
D41.9 Urinary organ, unspecified	0.000	0.995	0.005
D41.7 Other urinary organs	0.000	0.995	0.005
D41.3 Urethra	0.000	0.995	0.005
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.995	0.005
O46.9 Antepartum haemorrhage, unspecified	0.005	0.995	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.005	0.995	0.000
D41.4 Bladder	0.000	0.995	0.005
O21.9 Vomiting of pregnancy, unspecified	0.005	0.995	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.005	0.995	0.000
D43.1 Brain, infratentorial	0.000	0.995	0.005
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O86.8 Other specified puerperal infections	0.005	0.995	0.000
O92.1 Cracked nipple associated with childbirth	0.005	0.995	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.005	0.995	0.000
O90.5 Postpartum thyroiditis	0.005	0.995	0.000
O90.4 Postpartum acute renal failure	0.005	0.995	0.000
O90.3 Cardiomyopathy in the puerperium	0.005	0.995	0.000
O22.1 Genital varices in pregnancy	0.005	0.995	0.000
O82.0 Delivery by elective Caesarean section	0.005	0.995	0.000
D39.0 Uterus	0.000	0.995	0.005
B95-B98 Bacterial, viral and other infectious agents	0.000	0.995	0.005
O43.8 Other placental disorders	0.005	0.995	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.005	0.995	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.005	0.995	0.000
O90.2 Haematoma of obstetric wound	0.005	0.995	0.000
D41.1 Renal pelvis	0.000	0.995	0.005
O47.0 False labour before 37 completed weeks of gestation	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.995	0.005
D39.9 Female genital organ, unspecified	0.000	0.995	0.005
D39.2 Placenta	0.000	0.995	0.005
O72.0 Third-stage haemorrhage	0.005	0.995	0.000
J33.9 Nasal polyp, unspecified	0.000	0.995	0.005
D43.0 Brain, supratentorial	0.000	0.995	0.005
V18.0 Driver injured in nontraffic accident	0.000	0.995	0.005
D37.7 Other digestive organs	0.000	0.995	0.005
D41.0 Kidney	0.000	0.995	0.005
E27 Other disorders of adrenal gland	0.000	0.995	0.005
O23.5 Infections of the genital tract in pregnancy	0.005	0.995	0.000
O71.4 Obstetric high vaginal laceration alone	0.004	0.995	0.001
O80.8 Other single spontaneous delivery	0.005	0.995	0.000
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
O43.1 Malformation of placenta	0.005	0.995	0.000
O45 Premature separation of placenta [abruptio placentae]	0.005	0.995	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.004	0.995	0.000
L57.0 Actinic keratosis	0.005	0.995	0.000
O97 Death from sequelae of direct obstetric causes	0.004	0.995	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.995	0.000
O95 Obstetric death of unspecified cause	0.004	0.995	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.004	0.995	0.000
O40 Polyhydramnios	0.005	0.995	0.000
O80.1 Spontaneous breech delivery	0.004	0.995	0.000
D39.7 Other female genital organs	0.000	0.995	0.004
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.004	0.995	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.004	0.995	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.004	0.995	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.004	0.995	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.004	0.995	0.000
E34 Other endocrine disorders	0.000	0.995	0.005
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.995	0.005
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.004	0.995	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.005	0.995	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.004	0.995	0.000
O80.9 Single spontaneous delivery, unspecified	0.005	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
D41.2 Ureter	0.000	0.996	0.004
O47.9 False labour, unspecified	0.004	0.996	0.000
O36.4 Maternal care for intra-uterine death	0.004	0.996	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.000	0.996	0.004
J92.0 Pleural plaque with presence of asbestos	0.004	0.996	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.004	0.996	0.000
O43.2 Morbidly adherent placenta	0.004	0.996	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.004	0.996	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.004	0.996	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.004	0.996	0.000
O06 Unspecified abortion	0.004	0.996	0.000
O21.8 Other vomiting complicating pregnancy	0.004	0.996	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.004	0.996	0.000
O36.6 Maternal care for excessive foetal growth	0.004	0.996	0.000
O90.0 Disruption of Caesarean section wound	0.004	0.996	0.001
O00 Ectopic pregnancy	0.004	0.996	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.996	0.004
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.996	0.004
O43.9 Placental disorder, unspecified	0.004	0.996	0.000
O41.1 Infection of amniotic sac and membranes	0.004	0.996	0.000
O01 Hydatidiform mole	0.004	0.996	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.000	0.996	0.004
E28.9 Ovarian dysfunction, unspecified	0.000	0.996	0.004
E28.8 Other ovarian dysfunction	0.000	0.996	0.004
E28.1 Androgen excess	0.000	0.996	0.004
E28.0 Oestrogen excess	0.000	0.996	0.004
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.004	0.996	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.004	0.996	0.000
O44.1 Placenta praevia with haemorrhage	0.004	0.996	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.996	0.004
O08 Complications following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O12.1 Gestational proteinuria	0.004	0.996	0.001
O21.2 Late vomiting of pregnancy	0.004	0.996	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.004	0.996	0.000
O41.0 Oligohydramnios	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
O07 Failed attempted abortion	0.004	0.996	0.000
O05 Other abortion	0.004	0.996	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.004
O36.1 Maternal care for other isoimmunisation	0.004	0.996	0.000
O43.0 Placental transfusion syndromes	0.004	0.996	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.996	0.004
E27.8 Other specified disorders of adrenal gland	0.000	0.996	0.004
E27.2 Addisonian crisis	0.000	0.996	0.004
O24.9 Diabetes mellitus in pregnancy, unspecified	0.004	0.996	0.000
O30.0 Twin pregnancy	0.004	0.996	0.000
E25 Adrenogenital disorders	0.000	0.996	0.004
O31 Complications specific to multiple gestation	0.004	0.996	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.996	0.004
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.996	0.004
O30.9 Multiple gestation, unspecified	0.004	0.996	0.000
O30.8 Other multiple gestation	0.004	0.996	0.000
O30.2 Quadruplet pregnancy	0.004	0.996	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.004	0.996	0.000
E24 Cushing's syndrome	0.000	0.996	0.004
O36.9 Maternal care for foetal problem, unspecified	0.004	0.996	0.000
O36.2 Maternal care for hydrops foetalis	0.004	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.004	0.996	0.000
O86.0 Infection of obstetric surgical wound	0.004	0.996	0.000
J92 Pleural plaque	0.004	0.996	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.996	0.004
O00.9 Ectopic pregnancy, unspecified	0.004	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.004	0.996	0.000
O71.8 Other specified obstetric trauma	0.003	0.996	0.001
O33.9 Maternal care for disproportion, unspecified	0.004	0.996	0.000
O21.0 Mild hyperemesis gravidarum	0.004	0.996	0.000
E29 Testicular dysfunction	0.000	0.996	0.004
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.996	0.004
O24.4 Diabetes mellitus arising in pregnancy	0.004	0.996	0.000
O33.8 Maternal care for disproportion of other origin	0.004	0.996	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.004	0.996	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.004	0.996	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.004	0.996	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.004	0.996	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.004	0.996	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.004	0.996	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations