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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80166972
log Bayes Factor = 9.23193
Chromosome 4   position 172,193,847  (GRCh37) Explore rs80166972 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
M80-M85 Disorders of bone density and structure
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
B95-B98 Bacterial, viral and other infectious agents
0.992 0.008 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.990 0.010 0.000
M81 Osteoporosis without pathological fracture
0.988 0.012 0.000
M65-M68 Disorders of synovium and tendon
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
M81.9 Osteoporosis, unspecified
0.981 0.019 0.000
M51 Other intervertebral disk disorders
0.980 0.020 0.000
Chapter XIV Diseases of the genitourinary system
0.977 0.023 0.000
M54 Dorsalgia
0.970 0.030 0.000
Chapter V Mental and behavioural disorders
0.969 0.031 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.969 0.031 0.000
M51.2 Other specified intervertebral disk displacement
0.969 0.031 0.000
G90-G99 Other disorders of the nervous system
0.964 0.036 0.000
M65 Synovitis and tenosynovitis
0.964 0.036 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.956 0.044 0.000
Chapter VII Diseases of the eye and adnexa
0.955 0.045 0.000
M45-M49 Spondylopathies
0.952 0.048 0.000
D50-D53 Nutritional anaemias
0.950 0.050 0.000
D50.9 Iron deficiency anaemia, unspecified
0.947 0.053 0.000
D50 Iron deficiency anaemia
0.947 0.053 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.946 0.054 0.000
Chapter XXI Factors influencing health status and contact with health services
0.941 0.059 0.000
M20-M25 Other joint disorders
0.939 0.061 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.939 0.061 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.932 0.068 0.000
M54.5 Low back pain
0.931 0.069 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.931 0.069 0.000
N00-N08 Glomerular diseases
0.931 0.069 0.000
M47 Spondylosis
0.931 0.069 0.000
N30-N39 Other diseases of urinary system
0.927 0.073 0.000
N60-N64 Disorders of breast
0.923 0.077 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.917 0.083 0.000
M05-M14 Inflammatory polyarthropathies
0.914 0.086 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.905 0.095 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.900 0.100 0.000
H30-H36 Disorders of choroid and retina
0.897 0.103 0.000
G93 Other disorders of brain
0.896 0.104 0.000
M47.8 Other spondylosis
0.895 0.105 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.890 0.110 0.000
M67 Other disorders of synovium and tendon
0.887 0.113 0.000
M54.57 Low back pain (Lumbosacral region)
0.886 0.114 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.882 0.118 0.000
F03 Unspecified dementia
0.879 0.121 0.000
N03 Chronic nephritic syndrome
0.874 0.126 0.000
N61 Inflammatory disorders of breast
0.872 0.128 0.000
M81.98 Osteoporosis, unspecified (Other)
0.870 0.130 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.869 0.131 0.000
N62 Hypertrophy of breast
0.867 0.133 0.000
N32 Other disorders of bladder
0.867 0.133 0.000
M35 Other systemic involvement of connective tissue
0.862 0.138 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.861 0.139 0.000
Z73 Problems related to life-management difficulty
0.859 0.141 0.000
M54.2 Cervicalgia
0.852 0.148 0.000
S40-S49 Injuries to the shoulder and upper arm
0.850 0.150 0.000
T79-T79 Certain early complications of trauma
0.845 0.155 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.844 0.156 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.844 0.156 0.000
M47.86 Other spondylosis (Lumbar region)
0.843 0.157 0.000
A80-A89 Viral infections of the central nervous system
0.842 0.158 0.000
H35 Other retinal disorders
0.841 0.159 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.841 0.159 0.000
M40-M43 Deforming dorsopathies
0.840 0.160 0.000
H52 Disorders of refraction and accommodation
0.836 0.164 0.000
N32.3 Diverticulum of bladder
0.835 0.165 0.000
Z74 Problems related to care-provider dependency
0.835 0.165 0.000
M86-M90 Other osteopathies
0.834 0.166 0.000
N03.9 Unspecified
0.834 0.166 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.833 0.167 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.833 0.167 0.000
N10-N16 Renal tubulo-interstitial diseases
0.832 0.168 0.000
Z75 Problems related to medical facilities and other health care
0.831 0.169 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.830 0.170 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.826 0.174 0.000
M07 Psoriatic and enteropathic arthropathies
0.825 0.175 0.000
F80-F89 Disorders of psychological development
0.825 0.175 0.000
M85 Other disorders of bone density and structure
0.822 0.178 0.000
H35.3 Degeneration of macula and posterior pole
0.817 0.183 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.816 0.184 0.000
G96 Other disorders of central nervous system
0.813 0.187 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.809 0.191 0.000
M54.4 Lumbago with sciatica
0.807 0.193 0.000
M24 Other specific joint derangements
0.807 0.193 0.000
N72 Inflammatory disease of cervix uteri
0.806 0.194 0.000
M21 Other acquired deformities of limbs
0.804 0.196 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.803 0.197 0.000
M47.9 Spondylosis, unspecified
0.802 0.198 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.801 0.199 0.000
M67.8 Other specified disorders of synovium and tendon
0.801 0.199 0.000
N36 Other disorders of urethra
0.801 0.199 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.800 0.200 0.000
B15-B19 Viral hepatitis
0.797 0.203 0.000
M81.4 Drug-induced osteoporosis
0.797 0.203 0.000
B65-B83 Helminthiases
0.797 0.203 0.000
G93.9 Disorder of brain, unspecified
0.795 0.205 0.000
Z60 Problems related to social environment
0.790 0.210 0.000
M25 Other joint disorders, not elsewhere classified
0.789 0.211 0.000
M80 Osteoporosis with pathological fracture
0.787 0.213 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.786 0.214 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.784 0.216 0.000
O60-O75 Complications of labour and delivery
0.782 0.218 0.000
M51.8 Other specified intervertebral disk disorders
0.781 0.219 0.000
M54.22 Cervicalgia (Cervical region)
0.781 0.219 0.000
M65.3 Trigger finger
0.779 0.221 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.777 0.223 0.000
N13 Obstructive and reflux uropathy
0.777 0.223 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.773 0.226 0.000
G90 Disorders of autonomic nervous system
0.772 0.228 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.771 0.229 0.000
B50-B64 Protozoal diseases
0.768 0.232 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.768 0.232 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.767 0.233 0.000
G93.8 Other specified disorders of brain
0.767 0.233 0.000
G57 Mononeuropathies of lower limb
0.766 0.234 0.000
M54.56 Low back pain (Lumbar region)
0.766 0.234 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.766 0.234 0.000
G51 Facial nerve disorders
0.765 0.235 0.000
G93.6 Cerebral oedema
0.765 0.235 0.000
F00 Dementia in Alzheimer's disease
0.764 0.236 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.763 0.237 0.000
O00-O08 Pregnancy with abortive outcome
0.763 0.237 0.000
G95 Other diseases of spinal cord
0.762 0.238 0.000
M07.3 Other psoriatic arthropathies
0.762 0.238 0.000
G58 Other mononeuropathies
0.761 0.238 0.000
Z51 Other medical care
0.760 0.240 0.000
G70-G73 Diseases of myoneural junction and muscle
0.759 0.241 0.000
M00-M03 Infectious arthropathies
0.759 0.241 0.000
N60 Benign mammary dysplasia
0.758 0.242 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.754 0.246 0.000
M65.1 Other infective (teno)synovitis
0.752 0.248 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.752 0.248 0.000
S42 Fracture of shoulder and upper arm
0.750 0.250 0.000
Z73.3 Stress, not elsewhere classified
0.748 0.252 0.000
T18 Foreign body in alimentary tract
0.747 0.253 0.000
Chapter VIII Diseases of the ear and mastoid process
0.746 0.254 0.000
M35.0 Sicca syndrome [Sjogren]
0.746 0.254 0.000
H31 Other disorders of choroid
0.742 0.258 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.741 0.259 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.738 0.262 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.738 0.262 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.738 0.262 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.738 0.262 0.000
Z51.5 Palliative care
0.737 0.263 0.000
H10-H13 Disorders of conjunctiva
0.736 0.264 0.000
G81 Hemiplegia
0.735 0.265 0.000
F01 Vascular dementia
0.735 0.265 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.735 0.265 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.734 0.266 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.733 0.267 0.000
Z60.2 Living alone
0.733 0.267 0.000
A87 Viral meningitis
0.732 0.268 0.000
N35 Urethral stricture
0.732 0.268 0.000
N32.8 Other specified disorders of bladder
0.731 0.269 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.731 0.269 0.000
Z74.0 Reduced mobility
0.730 0.269 0.000
M82 Osteoporosis in diseases classified elsewhere
0.730 0.270 0.000
H49 Paralytic strabismus
0.727 0.273 0.000
M35.3 Polymyalgia rheumatica
0.726 0.274 0.000
M48 Other spondylopathies
0.726 0.274 0.000
M84 Disorders of continuity of bone
0.726 0.274 0.000
Z56 Problems related to employment and unemployment
0.725 0.274 0.000
M47.84 Other spondylosis (Thoracic region)
0.723 0.277 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.723 0.277 0.000
M54.3 Sciatica
0.723 0.277 0.000
H33 Retinal detachments and breaks
0.722 0.278 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.722 0.278 0.000
M65.8 Other synovitis and tenosynovitis
0.721 0.278 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.721 0.279 0.000
M53 Other dorsopathies, not elsewhere classified
0.720 0.280 0.000
M66 Spontaneous rupture of synovium and tendon
0.720 0.280 0.000
Z43 Attention to artificial openings
0.720 0.280 0.000
F81 Specific developmental disorders of scholastic skills
0.719 0.281 0.000
M14 Arthropathies in other diseases classified elsewhere
0.719 0.281 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.718 0.282 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.718 0.282 0.000
N04 Nephrotic syndrome
0.718 0.282 0.000
M47.1 Other spondylosis with myelopathy
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
M23 Internal derangement of knee
0.715 0.285 0.000
M83 Adult osteomalacia
0.714 0.286 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
M06 Other rheumatoid arthritis
0.713 0.287 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.287 0.000
B25-B34 Other viral diseases
0.712 0.288 0.000
G94.1 Hydrocephalus in neoplastic disease
0.709 0.291 0.000
M81.8 Other osteoporosis
0.709 0.291 0.000
M81.6 Localised osteoporosis [Lequesne]
0.709 0.291 0.000
M81.5 Idiopathic osteoporosis
0.709 0.291 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.709 0.291 0.000
M81.2 Osteoporosis of disuse
0.709 0.291 0.000
M81.1 Postoophorectomy osteoporosis
0.709 0.291 0.000
M81.0 Postmenopausal osteoporosis
0.709 0.291 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.708 0.291 0.000
M51.9 Intervertebral disk disorder, unspecified
0.708 0.292 0.000
F02 Dementia in other diseases classified elsewhere
0.708 0.292 0.000
O02 Other abnormal products of conception
0.703 0.297 0.000
Z52 Donors of organs and tissues
0.703 0.297 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.703 0.297 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.703 0.297 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.703 0.297 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.703 0.297 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.703 0.297 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.703 0.297 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.703 0.297 0.000
M54.55 Low back pain (Thoracolumbar region)
0.703 0.297 0.000
M51.3 Other specified intervertebral disk degeneration
0.702 0.297 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.702 0.297 0.000
M51.4 Schmorl's nodes
0.702 0.297 0.000
Z74.8 Other problems related to care-provider dependency
0.702 0.298 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.702 0.298 0.000
D52 Folate deficiency anaemia
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.700 0.300 0.000
M25.8 Other specified joint disorders
0.700 0.300 0.000
N36.8 Other specified disorders of urethra
0.700 0.300 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.699 0.301 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.698 0.302 0.000
Z75.3 Unavailability and inaccessibility of health-care facilities
0.697 0.303 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
M25.7 Osteophyte
0.696 0.304 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.695 0.304 0.000
M54.8 Other dorsalgia
0.695 0.305 0.000
M54.0 Panniculitis affecting regions of neck and back
0.695 0.305 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.695 0.305 0.000
F70-F79 Mental retardation
0.695 0.305 0.000
N05 Unspecified nephritic syndrome
0.694 0.306 0.000
T79.8 Other early complications of trauma
0.693 0.307 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.691 0.309 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.691 0.309 0.000
G92 Toxic encephalopathy
0.691 0.309 0.000
M65.2 Calcific tendinitis
0.691 0.309 0.000
M65.0 Abscess of tendon sheath
0.691 0.309 0.000
H52.3 Anisometropia and aniseikonia
0.691 0.309 0.000
M89 Other disorders of bone
0.690 0.310 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.690 0.310 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.688 0.312 0.000
T18.1 Foreign body in oesophagus
0.688 0.312 0.000
M24.2 Disorder of ligament
0.688 0.312 0.000
M43 Other deforming dorsopathies
0.686 0.314 0.000
S42.2 Fracture of upper end of humerus
0.686 0.314 0.000
O03 Spontaneous abortion
0.685 0.315 0.000
M11 Other crystal arthropathies
0.685 0.315 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.685 0.315 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.684 0.316 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.683 0.317 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.683 0.317 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.683 0.317 0.000
M23.3 Other meniscus derangements
0.683 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.682 0.317 0.000
Z40 Prophylactic surgery
0.682 0.318 0.000
M91-M94 Chondropathies
0.682 0.318 0.000
D53 Other nutritional anaemias
0.681 0.318 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.681 0.319 0.000
H65-H75 Diseases of middle ear and mastoid
0.680 0.320 0.000
G82 Paraplegia and tetraplegia
0.680 0.320 0.000
D50.1 Sideropenic dysphagia
0.679 0.321 0.000
M34 Systemic sclerosis
0.679 0.321 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.678 0.322 0.000
H52.7 Disorder of refraction, unspecified
0.678 0.322 0.000
H35.0 Background retinopathy and retinal vascular changes
0.678 0.322 0.000
T17 Foreign body in respiratory tract
0.677 0.323 0.000
H52.2 Astigmatism
0.675 0.325 0.000
Z51.2 Other chemotherapy
0.674 0.326 0.000
M85.8 Other specified disorders of bone density and structure
0.674 0.326 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
M33 Dermatopolymyositis
0.674 0.326 0.000
M32 Systemic lupus erythematosus
0.674 0.326 0.000
M30 Polyarteritis nodosa and related conditions
0.674 0.326 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.673 0.327 0.000
M67.1 Other contracture of tendon (sheath)
0.673 0.327 0.000
D55-D59 Haemolytic anaemias
0.672 0.327 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.672 0.328 0.000
H50 Other strabismus
0.672 0.328 0.000
H52.0 Hypermetropia
0.672 0.328 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.671 0.329 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.670 0.330 0.000
M21.1 Varus deformity, not elsewhere classified
0.668 0.332 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.668 0.332 0.000
F09 Unspecified organic or symptomatic mental disorder
0.668 0.332 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.668 0.332 0.000
M54.54 Low back pain-Thoracic
0.668 0.332 0.000
M54.53 Low back pain-Cervicothoracic
0.668 0.332 0.000
M54.52 Low back pain-Cervical
0.668 0.332 0.000
M54.51 Low back pain-Occipit-atl-axl
0.668 0.332 0.000
M54.50 Low back pain (Multiple sites in spine)
0.668 0.332 0.000
Z43.3 Attention to colostomy
0.668 0.332 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.667 0.333 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.667 0.333 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.667 0.333 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.667 0.333 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.667 0.333 0.000
N06 Isolated proteinuria with specified morphological lesion
0.667 0.333 0.000
N01 Rapidly progressive nephritic syndrome
0.667 0.333 0.000
N00 Acute nephritic syndrome
0.667 0.333 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.667 0.333 0.000
M54.6 Pain in thoracic spine
0.665 0.335 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.665 0.335 0.000
N37 Urethral disorders in diseases classified elsewhere
0.665 0.335 0.000
N33 Bladder disorders in diseases classified elsewhere
0.665 0.335 0.000
G20-G26 Extrapyramidal and movement disorders
0.665 0.335 0.000
M41 Scoliosis
0.664 0.336 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.663 0.337 0.000
O85-O92 Complications predominantly related to the puerperium
0.662 0.338 0.000
N34 Urethritis and urethral syndrome
0.661 0.339 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.660 0.340 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.659 0.340 0.000
G96.0 Cerebrospinal fluid leak
0.659 0.341 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.659 0.341 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.659 0.341 0.000
D51 Vitamin B12 deficiency anaemia
0.659 0.341 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.658 0.342 0.000
G91 Hydrocephalus
0.658 0.342 0.000
N60.0 Solitary cyst of breast
0.658 0.342 0.000
G81.9 Hemiplegia, unspecified
0.657 0.343 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.657 0.343 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.656 0.344 0.000
S40 Superficial injury of shoulder and upper arm
0.656 0.344 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.656 0.344 0.000
H43-H45 Disorders of vitreous body and globe
0.656 0.344 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.656 0.344 0.000
M13 Other arthritis
0.656 0.344 0.000
B80 Enterobiasis
0.656 0.344 0.000
M12 Other specific arthropathies
0.655 0.345 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.655 0.345 0.000
M08 Juvenile arthritis
0.655 0.345 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.654 0.346 0.000
A87.9 Viral meningitis, unspecified
0.654 0.346 0.000
M87 Osteonecrosis
0.654 0.346 0.000
Z76 Persons encountering health services in other circumstances
0.654 0.346 0.000
S42.4 Fracture of lower end of humerus
0.653 0.347 0.000
M35.7 Hypermobility syndrome
0.652 0.347 0.000
H53-H54 Visual disturbances and blindness
0.652 0.348 0.000
Z75.8 Other problems related to medical facilities and other health care
0.652 0.348 0.000
H04 Disorders of lachrymal system
0.652 0.348 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.652 0.348 0.000
S10-S19 Injuries to the neck
0.652 0.348 0.000
N36.0 Urethral fistula
0.652 0.348 0.000
S43.0 Dislocation of shoulder joint
0.651 0.349 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.651 0.349 0.000
O02.1 Missed abortion
0.650 0.350 0.000
G30-G32 Other degenerative diseases of the nervous system
0.650 0.350 0.000
T33-T35 Frostbite
0.649 0.351 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.649 0.351 0.000
T00-T07 Injuries involving multiple body regions
0.649 0.351 0.000
O62 Abnormalities of forces of labour
0.649 0.351 0.000
G58.9 Mononeuropathy, unspecified
0.649 0.351 0.000
N76 Other inflammation of vagina and vulva
0.649 0.351 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.648 0.352 0.000
N99-N99 Other disorders of the genitourinary system
0.648 0.352 0.000
H34 Retinal vascular occlusions
0.648 0.352 0.000
M65.34 Trigger finger-Hand
0.647 0.353 0.000
M47.2 Other spondylosis with radiculopathy
0.647 0.353 0.000
H51 Other disorders of binocular movement
0.646 0.354 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.644 0.356 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.643 0.357 0.000
H30 Chorioretinal inflammation
0.643 0.357 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.643 0.357 0.000
G93.7 Reye's syndrome
0.642 0.358 0.000
G93.5 Compression of brain
0.642 0.358 0.000
G93.2 Benign intracranial hypertension
0.642 0.358 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.642 0.358 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.642 0.358 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.642 0.358 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.642 0.358 0.000
G51.0 Bell's palsy
0.640 0.360 0.000
H21 Other disorders of iris and ciliary body
0.639 0.361 0.000
S42.20 Fracture of upper end of humerus (closed)
0.639 0.361 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.638 0.362 0.000
G52 Disorders of other cranial nerves
0.638 0.362 0.000
H40-H42 Glaucoma
0.638 0.362 0.000
H33.3 Retinal breaks without detachment
0.637 0.363 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.637 0.363 0.000
M10 Gout
0.636 0.364 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.636 0.364 0.000
M67.4 Ganglion
0.636 0.364 0.000
M67.3 Transient synovitis
0.636 0.364 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.636 0.364 0.000
M67.0 Short Achilles tendon (acquired)
0.636 0.364 0.000
N10 Acute tubulo-interstitial nephritis
0.635 0.365 0.000
G90.2 Horner's syndrome
0.634 0.365 0.000
H20 Iridocyclitis
0.632 0.367 0.000
S90-S99 Injuries to the ankle and foot
0.632 0.368 0.000
H31.0 Chorioretinal scars
0.630 0.370 0.000
Z51.1 Chemotherapy session for neoplasm
0.630 0.370 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.630 0.370 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.629 0.371 0.000
S41 Open wound of shoulder and upper arm
0.629 0.371 0.000
N71 Inflammatory disease of uterus, except cervix
0.628 0.372 0.000
D80-D89 Certain disorders involving the immune mechanism
0.628 0.372 0.000
N03.8 Other
0.627 0.373 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.627 0.373 0.000
N03.6 Dense deposit disease
0.627 0.373 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.627 0.373 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.627 0.373 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.627 0.373 0.000
N03.2 Diffuse membranous glomerulonephritis
0.627 0.373 0.000
N03.1 Focal and segmental glomerular lesions
0.627 0.373 0.000
N03.0 Minor glomerular abnormality
0.627 0.373 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.626 0.374 0.000
M22 Disorders of patella
0.626 0.374 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.625 0.375 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.624 0.376 0.000
O03.9 Complete or unspecified, without complication
0.624 0.376 0.000
H16 Keratitis
0.624 0.376 0.000
Z65 Problems related to other psychosocial circumstances
0.623 0.377 0.000
Z64 Problems related to certain psychosocial circumstances
0.623 0.377 0.000
Z62 Other problems related to upbringing
0.623 0.377 0.000
Z61 Problems related to negative life events in childhood
0.623 0.377 0.000
Z59 Problems related to housing and economic circumstances
0.623 0.377 0.000
Z58 Problems related to physical environment
0.623 0.377 0.000
Z55 Problems related to education and literacy
0.623 0.377 0.000
M54.39 Sciatica (Site unspecified)
0.623 0.377 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.622 0.378 0.000
G12 Spinal muscular atrophy and related syndromes
0.622 0.378 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.622 0.378 0.000
B35-B49 Mycoses
0.622 0.378 0.000
N32.4 Rupture of bladder, nontraumatic
0.621 0.379 0.000
N32.2 Vesical fistula, not elsewhere classified
0.621 0.379 0.000
N32.1 Vesicointestinal fistula
0.621 0.379 0.000
B15 Acute hepatitis A
0.621 0.379 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.621 0.379 0.000
G57.6 Lesion of plantar nerve
0.620 0.380 0.000
Z49 Care involving dialysis
0.620 0.380 0.000
M24.1 Other articular cartilage disorders
0.619 0.381 0.000
G57.8 Other mononeuropathies of lower limb
0.618 0.382 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.618 0.382 0.000
M35.8 Other specified systemic involvement of connective tissue
0.618 0.382 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.618 0.382 0.000
M35.5 Multifocal fibrosclerosis
0.618 0.382 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.618 0.382 0.000
M35.2 Behcet's disease
0.618 0.382 0.000
M35.1 Other overlap syndromes
0.618 0.382 0.000
O72 Postpartum haemorrhage
0.618 0.382 0.000
N13.3 Other and unspecified hydronephrosis
0.617 0.383 0.000
A30-A49 Other bacterial diseases
0.617 0.383 0.000
M70-M79 Other soft tissue disorders
0.617 0.383 0.000
Q60-Q64 Congenital malformations of the urinary system
0.617 0.383 0.000
H73 Other disorders of tympanic membrane
0.616 0.384 0.000
M21.0 Valgus deformity, not elsewhere classified
0.616 0.384 0.000
Z73.8 Other problems related to life-management difficulty
0.616 0.384 0.000
Z73.6 Limitation of activities due to disability
0.616 0.384 0.000
Z73.5 Social role conflict, not elsewhere classified
0.616 0.384 0.000
Z73.4 Inadequate social skills, not elsewhere classified
0.616 0.384 0.000
Z73.2 Lack of relaxation and leisure
0.616 0.384 0.000
Z73.1 Accentuation of personality traits
0.616 0.384 0.000
Z73.0 Burn-out
0.616 0.384 0.000
Z63 Other problems related to primary support group, including family circumstances
0.614 0.385 0.000
N13.4 Hydroureter
0.614 0.386 0.000
Z52.4 Kidney donor
0.613 0.387 0.000
M47.89 Other spondylosis (Site unspecified)
0.613 0.387 0.000
M21.6 Other acquired deformities of ankle and foot
0.612 0.388 0.000
T21 Burn and corrosion of trunk
0.612 0.388 0.000
M85.6 Other cyst of bone
0.611 0.388 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.611 0.389 0.000
M54.27 Cervicalgia-Lumbosacral
0.611 0.389 0.000
M54.26 Cervicalgia-Lumbar
0.611 0.389 0.000
M54.25 Cervicalgia-Thoracolumbar
0.611 0.389 0.000
M54.24 Cervicalgia-Thoracic
0.611 0.389 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.611 0.389 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.611 0.389 0.000
M54.20 Cervicalgia-Mult site
0.611 0.389 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.611 0.389 0.000
G51.3 Clonic hemifacial spasm
0.611 0.389 0.000
M25.76 Osteophyte (Lower leg)
0.610 0.390 0.000
O66 Other obstructed labour
0.610 0.390 0.000
G93.4 Encephalopathy, unspecified
0.610 0.390 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.610 0.390 0.000
S48 Traumatic amputation of shoulder and upper arm
0.609 0.390 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.609 0.390 0.000
S44 Injury of nerves at shoulder and upper arm level
0.609 0.390 0.000
S47 Crushing injury of shoulder and upper arm
0.609 0.390 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.609 0.391 0.000
G54 Nerve root and plexus disorders
0.608 0.392 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.608 0.392 0.000
Z57 Occupational exposure to risk-factors
0.608 0.392 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.607 0.392 0.000
M25.86 Other specified joint disorders (Lower leg)
0.608 0.392 0.000
H35.4 Peripheral retinal degeneration
0.607 0.393 0.000
G50 Disorders of trigeminal nerve
0.607 0.393 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.607 0.393 0.000
F22 Persistent delusional disorders
0.607 0.393 0.000
Q50-Q56 Congenital malformations of genital organs
0.605 0.394 0.000
B59 Pneumocystosis
0.605 0.395 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.605 0.395 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.605 0.395 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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