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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8045334
log Bayes Factor = <0.0001
Chromosome 16   position 63,573,376  (GRCh37) Explore rs8045334 on Ensembl!
Variant rs8045334 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.025 0.975 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.025 0.975 0.000
M06.9 Rheumatoid arthritis, unspecified
0.024 0.976 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.020 0.980 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.020 0.980 0.000
Q23.1 Congenital insufficiency of aortic valve
0.000 0.981 0.019
O20.0 Threatened abortion
0.000 0.981 0.019
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.017 0.983 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.016 0.984 0.000
Q23 Congenital malformations of aortic and mitral valves
0.000 0.984 0.016
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.016 0.984 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.015 0.985 0.000
Q23.0 Congenital stenosis of aortic valve
0.000 0.985 0.015
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.014 0.986 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.012 0.988 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.000 0.988 0.012
Q23.8 Other congenital malformations of aortic and mitral valves
0.000 0.988 0.012
Q23.4 Hypoplastic left heart syndrome
0.000 0.988 0.012
Q23.3 Congenital mitral insufficiency
0.000 0.988 0.012
Q23.2 Congenital mitral stenosis
0.000 0.988 0.012
Q20-Q28 Congenital malformations of the circulatory system
0.000 0.989 0.011
Q24 Other congenital malformations of heart
0.000 0.990 0.010
Q25 Congenital malformations of great arteries
0.000 0.991 0.009
M06 Other rheumatoid arthritis
0.009 0.991 0.000
U88 Agent resistant to multiple antibiotics
0.000 0.991 0.009
H18.9 Disorder of cornea, unspecified
0.009 0.991 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.000 0.991 0.008
H18 Other disorders of cornea
0.009 0.991 0.000
Q24.8 Other specified congenital malformations of heart
0.000 0.992 0.008
M13.90 Arthritis, unspecified (Multiple sites)
0.008 0.992 0.000
Q27 Other congenital malformations of peripheral vascular system
0.000 0.992 0.008
F17.2 Dependence syndrome
0.000 0.992 0.008
Q28 Other congenital malformations of circulatory system
0.000 0.992 0.008
Q26 Congenital malformations of great veins
0.000 0.992 0.008
Q20 Congenital malformations of cardiac chambers and connexions
0.000 0.992 0.008
N80.0 Endometriosis of uterus
0.000 0.992 0.008
H18.8 Other specified disorders of cornea
0.008 0.992 0.000
K85.1 Biliary acute pancreatitis
0.008 0.992 0.000
H18.3 Changes in corneal membranes
0.007 0.993 0.000
Q25.1 Coarctation of aorta
0.000 0.993 0.007
H18.5 Hereditary corneal dystrophies
0.007 0.993 0.000
Q24.0 Dextrocardia
0.000 0.993 0.007
Q25.4 Other congenital malformations of aorta
0.000 0.993 0.007
Q43 Other congenital malformations of intestine
0.000 0.993 0.007
Q24.6 Congenital heart block
0.000 0.993 0.007
Q24.4 Congenital subaortic stenosis
0.000 0.993 0.007
Q24.3 Pulmonary infundibular stenosis
0.000 0.993 0.007
Q24.2 Cor triatriatum
0.000 0.993 0.007
Q24.1 Levocardia
0.000 0.993 0.007
G82.1 Spastic paraplegia
0.000 0.993 0.007
M06.4 Inflammatory polyarthropathy
0.007 0.993 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.000 0.993 0.007
H18.4 Corneal degeneration
0.007 0.993 0.000
G82.2 Paraplegia, unspecified
0.000 0.993 0.007
Q28.2 Arteriovenous malformation of cerebral vessels
0.000 0.993 0.007
H18.2 Other corneal oedema
0.007 0.993 0.000
Q25.3 Stenosis of aorta
0.000 0.993 0.007
Q27.3 Peripheral arteriovenous malformation
0.000 0.993 0.007
Q43.8 Other specified congenital malformations of intestine
0.000 0.993 0.007
H18.0 Corneal pigmentations and deposits
0.007 0.993 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.000 0.993 0.007
Q25.8 Other congenital malformations of great arteries
0.000 0.993 0.007
Q25.7 Other congenital malformations of pulmonary artery
0.000 0.993 0.007
Q25.5 Atresia of pulmonary artery
0.000 0.993 0.007
Q25.2 Atresia of aorta
0.000 0.993 0.007
Q25.6 Stenosis of pulmonary artery
0.000 0.993 0.007
Q25.0 Patent ductus arteriosus
0.000 0.993 0.007
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.000 0.993 0.007
Q43.9 Congenital malformation of intestine, unspecified
0.000 0.993 0.007
M06.2 Rheumatoid bursitis
0.007 0.993 0.000
M06.1 Adult-onset Still's disease
0.007 0.993 0.000
M06.8 Other specified rheumatoid arthritis
0.007 0.993 0.000
O20 Haemorrhage in early pregnancy
0.000 0.993 0.007
G82 Paraplegia and tetraplegia
0.000 0.993 0.007
Q24.5 Malformation of coronary vessels
0.000 0.993 0.006
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.007 0.993 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.006 0.994 0.000
H18.7 Other corneal deformities
0.006 0.994 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.000 0.994 0.006
Q38.7 Pharyngeal pouch
0.000 0.994 0.006
R02 Gangrene, not elsewhere classified
0.000 0.994 0.006
Q27.4 Congenital phlebectasia
0.000 0.994 0.006
Q27.2 Other congenital malformations of renal artery
0.000 0.994 0.006
Q27.1 Congenital renal artery stenosis
0.000 0.994 0.006
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.000 0.994 0.006
H18.6 Keratoconus
0.006 0.994 0.000
Q43.0 Meckel's diverticulum
0.000 0.994 0.006
Q38 Other congenital malformations of tongue, mouth and pharynx
0.000 0.994 0.006
H18.1 Bullous keratopathy
0.006 0.994 0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.000 0.994 0.006
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.000 0.994 0.006
Q20.6 Isomerism of atrial appendages
0.000 0.994 0.006
Q20.5 Discordant atrioventricular connexion
0.000 0.994 0.006
Q20.4 Double inlet ventricle
0.000 0.994 0.006
Q20.3 Discordant ventriculoarterial connexion
0.000 0.994 0.006
Q20.2 Double outlet left ventricle
0.000 0.994 0.006
Q20.1 Double outlet right ventricle
0.000 0.994 0.006
Q20.0 Common arterial trunk
0.000 0.994 0.006
Q26.9 Congenital malformation of great vein, unspecified
0.000 0.994 0.006
Q26.8 Other congenital malformations of great veins
0.000 0.994 0.006
Q26.6 Portal vein-hepatic artery fistula
0.000 0.994 0.006
Q26.5 Anomalous portal venous connexion
0.000 0.994 0.006
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.000 0.994 0.006
Q26.3 Partial anomalous pulmonary venous connexion
0.000 0.994 0.006
Q26.2 Total anomalous pulmonary venous connexion
0.000 0.994 0.006
Q26.1 Persistent left superior vena cava
0.000 0.994 0.006
Q26.0 Congenital stenosis of vena cava
0.000 0.994 0.006
Q28.9 Congenital malformation of circulatory system, unspecified
0.000 0.994 0.006
Q28.8 Other specified congenital malformations of circulatory system
0.000 0.994 0.006
Q28.1 Other malformations of precerebral vessels
0.000 0.994 0.006
Q43.1 Hirschsprung's disease
0.000 0.994 0.006
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.994 0.006
M06.46 Inflammatory polyarthropathy (Lower leg)
0.005 0.994 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.006 0.994 0.000
Q43.7 Persistent cloaca
0.000 0.994 0.005
Q43.6 Congenital fistula of rectum and anus
0.000 0.994 0.005
Q43.5 Ectopic anus
0.000 0.994 0.005
Q43.4 Duplication of intestine
0.000 0.994 0.005
Q43.2 Other congenital functional disorders of colon
0.000 0.994 0.005
Q27.8 Other specified congenital malformations of peripheral vascular system
0.000 0.995 0.005
Q43.3 Congenital malformations of intestinal fixation
0.000 0.995 0.005
M06.48 Inflammatory polyarthropathy (Other)
0.005 0.995 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.005 0.995 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.005 0.995 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.005 0.995 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.005 0.995 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.005 0.995 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.005 0.995 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.000 0.995 0.005
Q22.8 Other congenital malformations of tricuspid valve
0.000 0.995 0.005
Q22.6 Hypoplastic right heart syndrome
0.000 0.995 0.005
Q22.5 Ebstein's anomaly
0.000 0.995 0.005
Q22.4 Congenital tricuspid stenosis
0.000 0.995 0.005
Q22.3 Other congenital malformations of pulmonary valve
0.000 0.995 0.005
Q22.2 Congenital pulmonary valve insufficiency
0.000 0.995 0.005
Q22.0 Pulmonary valve atresia
0.000 0.995 0.005
G82.5 Tetraplegia, unspecified
0.000 0.995 0.005
M06.3 Rheumatoid nodule
0.005 0.995 0.000
Q28.3 Other malformations of cerebral vessels
0.000 0.995 0.005
Q45 Other congenital malformations of digestive system
0.000 0.995 0.005
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.005 0.995 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.005 0.995 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.005 0.995 0.000
M06.18 Adult-onset Still's disease (Other)
0.005 0.995 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.005 0.995 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.005 0.995 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.005 0.995 0.000
M06.14 Adult-onset Still's disease (Hand)
0.005 0.995 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.005 0.995 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.005 0.995 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.005 0.995 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.005 0.995 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.005 0.995 0.000
M06.28 Rheumatoid bursitis (Other)
0.005 0.995 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.005 0.995 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.005 0.995 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.005 0.995 0.000
M06.24 Rheumatoid bursitis (Hand)
0.005 0.995 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.005 0.995 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.005 0.995 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.005 0.995 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.005 0.995 0.000
G82.4 Spastic tetraplegia
0.000 0.995 0.005
M06.0 Seronegative rheumatoid arthritis
0.005 0.995 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.005 0.995 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.005 0.995 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.005 0.995 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.005 0.995 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.005 0.995 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.005 0.995 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.005 0.995 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.005 0.995 0.000
G82.3 Flaccid tetraplegia
0.000 0.995 0.005
G82.0 Flaccid paraplegia
0.000 0.995 0.005
Q28.0 Arteriovenous malformation of precerebral vessels
0.000 0.995 0.005
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.005 0.995 0.000
Q39 Congenital malformations of oesophagus
0.000 0.995 0.005
Q42 Congenital absence, atresia and stenosis of large intestine
0.000 0.995 0.005
Q41 Congenital absence, atresia and stenosis of small intestine
0.000 0.995 0.005
Q40 Other congenital malformations of upper alimentary tract
0.000 0.995 0.005
O20.8 Other haemorrhage in early pregnancy
0.000 0.995 0.005
Q38.8 Other congenital malformations of pharynx
0.000 0.995 0.004
Q38.6 Other congenital malformations of mouth
0.000 0.995 0.004
Q38.5 Congenital malformations of palate, not elsewhere classified
0.000 0.995 0.004
Q38.4 Congenital malformations of salivary glands and ducts
0.000 0.995 0.004
Q38.3 Other congenital malformations of tongue
0.000 0.995 0.004
Q38.2 Macroglossia
0.000 0.995 0.004
Q38.0 Congenital malformations of lips, not elsewhere classified
0.000 0.995 0.004
Q22.1 Congenital pulmonary valve stenosis
0.000 0.995 0.004
U89 Agent resistant to other and unspecified antibiotics
0.000 0.995 0.005
O21.0 Mild hyperemesis gravidarum
0.000 0.995 0.005
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.004 0.995 0.000
Q45.8 Other specified congenital malformations of digestive system
0.000 0.996 0.004
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.000 0.996 0.004
Q21 Congenital malformations of cardiac septa
0.000 0.996 0.004
U84 Resistance to other antimicrobial drugs
0.000 0.996 0.004
U83 Resistance to other antibiotics
0.000 0.996 0.004
U82 Resistance to betalactam antibiotics
0.000 0.996 0.004
U85 Resistance to antineoplastic drugs
0.000 0.996 0.004
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.004 0.996 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.996 0.004
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.004 0.996 0.000
Q38.1 Ankyloglossia
0.000 0.996 0.004
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.004 0.996 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.996 0.004
M06.39 Rheumatoid nodule (Site unspecified)
0.004 0.996 0.000
M06.38 Rheumatoid nodule (Other)
0.004 0.996 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.004 0.996 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.004 0.996 0.000
M06.33 Rheumatoid nodule (Forearm)
0.004 0.996 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.004 0.996 0.000
U89.8 Agent resistant to other single specified antibiotic
0.000 0.996 0.004
Q45.9 Congenital malformation of digestive system, unspecified
0.000 0.996 0.004
Q45.3 Other congenital malformations of pancreas and pancreatic duct
0.000 0.996 0.004
Q45.2 Congenital pancreatic cyst
0.000 0.996 0.004
Q45.1 Annular pancreas
0.000 0.996 0.004
Q45.0 Agenesis, aplasia and hypoplasia of pancreas
0.000 0.996 0.004
Q39.4 Oesophageal web
0.000 0.996 0.004
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.004 0.996 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.004 0.996 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.004 0.996 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.004 0.996 0.000
M06.34 Rheumatoid nodule (Hand)
0.004 0.996 0.000
D43.2 Brain, unspecified
0.004 0.996 0.000
O21 Excessive vomiting in pregnancy
0.000 0.996 0.004
M06.08 Seronegative rheumatoid arthritis (Other)
0.004 0.996 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.004 0.996 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.004 0.996 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.004 0.996 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.004 0.996 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.004 0.996 0.000
Q40.2 Other specified congenital malformations of stomach
0.000 0.996 0.004
M06.37 Rheumatoid nodule (Ankle and foot)
0.004 0.996 0.000
Q39.9 Congenital malformation of oesophagus, unspecified
0.000 0.996 0.004
Q39.8 Other congenital malformations of oesophagus
0.000 0.996 0.004
Q39.5 Congenital dilatation of oesophagus
0.000 0.996 0.004
Q39.3 Congenital stenosis and stricture of oesophagus
0.000 0.996 0.004
Q39.2 Congenital tracheooesophageal fistula without atresia
0.000 0.996 0.004
Q39.1 Atresia of oesophagus with tracheooesophageal fistula
0.000 0.996 0.004
Q39.0 Atresia of oesophagus without fistula
0.000 0.996 0.004
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified
0.000 0.996 0.004
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine
0.000 0.996 0.004
Q41.2 Congenital absence, atresia and stenosis of ileum
0.000 0.996 0.004
Q41.1 Congenital absence, atresia and stenosis of jejunum
0.000 0.996 0.004
Q41.0 Congenital absence, atresia and stenosis of duodenum
0.000 0.996 0.004
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified
0.000 0.996 0.004
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine
0.000 0.996 0.004
Q42.3 Congenital absence, atresia and stenosis of anus without fistula
0.000 0.996 0.004
Q42.2 Congenital absence, atresia and stenosis of anus with fistula
0.000 0.996 0.004
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula
0.000 0.996 0.004
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula
0.000 0.996 0.004
M06.30 Rheumatoid nodule (Multiple sites)
0.003 0.996 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.004 0.996 0.000
I30.9 Acute pericarditis, unspecified
0.004 0.996 0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified
0.000 0.996 0.003
Q40.1 Congenital hiatus hernia
0.000 0.996 0.003
Q40.0 Congenital hypertrophic pyloric stenosis
0.000 0.996 0.003
M06.32 Rheumatoid nodule (Upper arm)
0.003 0.996 0.000
Q44.6 Cystic disease of liver
0.000 0.996 0.003
O21.8 Other vomiting complicating pregnancy
0.000 0.996 0.003
Q21.9 Congenital malformation of cardiac septum, unspecified
0.000 0.997 0.003
K59.8 Other specified functional intestinal disorders
0.000 0.997 0.003
O21.9 Vomiting of pregnancy, unspecified
0.000 0.997 0.003
Q39.6 Diverticulum of oesophagus
0.000 0.997 0.003
Q40.3 Congenital malformation of stomach, unspecified
0.000 0.997 0.003
Q44.7 Other congenital malformations of liver
0.000 0.997 0.003
Q44.4 Choledochal cyst
0.000 0.997 0.003
Q44.3 Congenital stenosis and stricture of bile ducts
0.000 0.997 0.003
Q44.2 Atresia of bile ducts
0.000 0.997 0.003
Q44.1 Other congenital malformations of gallbladder
0.000 0.997 0.003
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.000 0.997 0.003
Q21.8 Other congenital malformations of cardiac septa
0.000 0.997 0.003
Q21.4 Aortopulmonary septal defect
0.000 0.997 0.003
Q21.2 Atrioventricular septal defect
0.000 0.997 0.003
M05-M14 Inflammatory polyarthropathies
0.003 0.997 0.000
Q40.8 Other specified congenital malformations of upper alimentary tract
0.000 0.997 0.003
U82.9 Resistance to betalactam antibiotics, unspecified
0.000 0.997 0.003
U82.8 Resistance to other betalactam antibiotics
0.000 0.997 0.003
U82.2 Extended spectrum betalactamase (ESBL) resistance
0.000 0.997 0.003
U82.1 Resistance to methicillin
0.000 0.997 0.003
U82.0 Resistance to penicillin
0.000 0.997 0.003
U83.9 Resistance to unspecified antibiotic
0.000 0.997 0.003
U83.8 Resistance to other single specified antibiotic
0.000 0.997 0.003
U83.7 Resistance to multiple antibiotics
0.000 0.997 0.003
U83.2 Resistance to quinolones
0.000 0.997 0.003
U83.1 Resistance to other vancomycin related antibiotics
0.000 0.997 0.003
U83.0 Resistance to vancomycin
0.000 0.997 0.003
U84.9 Resistance to unspecified antimicrobial drugs
0.000 0.997 0.003
U84.8 Resistance to other specified antimicrobial drug
0.000 0.997 0.003
U84.7 Resistance to multiple antimicrobial drugs
0.000 0.997 0.003
U84.3 Resistance to tuberculostatic drug(s)
0.000 0.997 0.003
U84.2 Resistance to antiviral drug(s)
0.000 0.997 0.003
U84.1 Resistance to antifungal drug(s)
0.000 0.997 0.003
U84.0 Resistance to antiparasitic drug(s)
0.000 0.997 0.003
U89.9 Agent resistant to unspecified antibiotic
0.000 0.997 0.003
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.997 0.003
Q80-Q89 Other congenital malformations
0.000 0.997 0.003
Q30-Q34 Congenital malformations of the respiratory system
0.000 0.997 0.003
M05 Seropositive rheumatoid arthritis
0.003 0.997 0.000
Q82 Other congenital malformations of skin
0.000 0.997 0.003
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.003 0.997 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.000 0.997 0.003
M12 Other specific arthropathies
0.003 0.997 0.000
Q82.5 Congenital nonneoplastic naevus
0.000 0.997 0.003
Q21.3 Tetralogy of Fallot
0.000 0.997 0.003
M14 Arthropathies in other diseases classified elsewhere
0.003 0.997 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.003 0.997 0.000
M54.12 Radiculopathy (Cervical region)
0.000 0.997 0.003
O21.2 Late vomiting of pregnancy
0.000 0.997 0.003
M66.24 Spontaneous rupture of extensor tendons (Hand)
0.003 0.997 0.000
Q35-Q37 Cleft lip and cleft palate
0.000 0.997 0.003
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.000 0.997 0.003
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.000 0.997 0.003
M14.2 Diabetic arthropathy
0.003 0.997 0.000
M08 Juvenile arthritis
0.003 0.997 0.000
Q44.5 Other congenital malformations of bile ducts
0.000 0.997 0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.003 0.997 0.000
E87.7 Fluid overload
0.003 0.997 0.000
M05.2 Rheumatoid vasculitis
0.003 0.997 0.000
M12.3 Palindromic rheumatism
0.003 0.997 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.000 0.997 0.003
M12.2 Villonodular synovitis (pigmented)
0.003 0.997 0.000
K59.3 Megacolon, not elsewhere classified
0.000 0.997 0.003
M05.8 Other seropositive rheumatoid arthritis
0.003 0.997 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.003 0.997 0.000
Q82.8 Other specified congenital malformations of skin
0.000 0.997 0.003
M05.9 Seropositive rheumatoid arthritis, unspecified
0.003 0.997 0.000
M05.1 Rheumatoid lung disease
0.003 0.997 0.000
N05.9 Unspecified
0.003 0.997 0.000
Q82.2 Mastocytosis
0.000 0.997 0.003
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.002 0.997 0.000
Q21.0 Ventricular septal defect
0.000 0.997 0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.003 0.997 0.000
M14.6 Neuropathic arthropathy
0.003 0.997 0.000
Q18 Other congenital malformations of face and neck
0.000 0.997 0.003
Q34 Other congenital malformations of respiratory system
0.000 0.997 0.002
Q33 Congenital malformations of lung
0.000 0.997 0.002
Q32 Congenital malformations of trachea and bronchus
0.000 0.997 0.002
Q31 Congenital malformations of larynx
0.000 0.997 0.002
Q30 Congenital malformations of nose
0.000 0.997 0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.000 0.997 0.002
Q85 Phakomatoses, not elsewhere classified
0.000 0.997 0.003
Q84 Other congenital malformations of integument
0.000 0.997 0.002
Q81 Epidermolysis bullosa
0.000 0.997 0.002
Q80 Congenital ichthyosis
0.000 0.997 0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.002 0.997 0.000
M05.0 Felty's syndrome
0.002 0.997 0.000
Q82.9 Congenital malformation of skin, unspecified
0.000 0.997 0.002
Q82.4 Ectodermal dysplasia (anhidrotic)
0.000 0.997 0.002
Q82.3 Incontinentia pigmenti
0.000 0.997 0.002
Q82.1 Xeroderma pigmentosum
0.000 0.997 0.002
Q82.0 Hereditary lymphoedema
0.000 0.997 0.002
R54 Senility
0.000 0.997 0.003
Q60-Q64 Congenital malformations of the urinary system
0.000 0.997 0.002
M12.39 Palindromic rheumatism (Site unspecified)
0.002 0.997 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.000 0.997 0.002
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.997 0.000
M12.5 Traumatic arthropathy
0.002 0.997 0.000
M12.4 Intermittent hydrarthrosis
0.002 0.997 0.000
M12.1 Kaschin-Beck disease
0.002 0.997 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.997 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.000 0.997 0.003
M14.8 Arthropathies in other specified diseases classified elsewhere
0.002 0.997 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.002 0.997 0.000
M14.4 Arthropathy in amyloidosis
0.002 0.997 0.000
M14.3 Lipoid dermatoarthritis
0.002 0.997 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.002 0.997 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.002 0.997 0.000
M08.0 Juvenile rheumatoid arthritis
0.002 0.997 0.000
Chapter XXII Codes for special purposes
0.000 0.997 0.002
Q15 Other congenital malformations of eye
0.000 0.998 0.002
Q36 Cleft lip
0.000 0.998 0.002
Q35 Cleft palate
0.000 0.998 0.002
Q61 Cystic kidney disease
0.000 0.998 0.002
Q50-Q56 Congenital malformations of genital organs
0.000 0.998 0.002
Q00-Q07 Congenital malformations of the nervous system
0.000 0.998 0.002
M05.20 Rheumatoid vasculitis (Multiple sites)
0.002 0.998 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.002 0.998 0.000
Q85.9 Phakomatosis, unspecified
0.000 0.998 0.002
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.000 0.998 0.002
Q61.2 Polycystic kidney, adult type
0.000 0.998 0.002
M10 Gout
0.002 0.998 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.000 0.998 0.002
Q13 Congenital malformations of anterior segment of eye
0.000 0.998 0.002
M05.29 Rheumatoid vasculitis (Site unspecified)
0.002 0.998 0.000
Q17 Other congenital malformations of ear
0.000 0.998 0.002
M08.9 Juvenile arthritis, unspecified
0.002 0.998 0.000
M08.8 Other juvenile arthritis
0.002 0.998 0.000
M08.4 Pauciarticular juvenile arthritis
0.002 0.998 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.002 0.998 0.000
M08.2 Juvenile arthritis with systemic onset
0.002 0.998 0.000
M08.1 Juvenile ankylosing spondylitis
0.002 0.998 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.002 0.998 0.000
M10.0 Idiopathic gout
0.002 0.998 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.000 0.998 0.002
Q61.9 Cystic kidney disease, unspecified
0.000 0.998 0.002
O23 Infections of genito-urinary tract in pregnancy
0.000 0.998 0.002
M12.38 Palindromic rheumatism (Other)
0.002 0.998 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.002 0.998 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.002 0.998 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.002 0.998 0.000
M12.34 Palindromic rheumatism (Hand)
0.002 0.998 0.000
M12.33 Palindromic rheumatism (Forearm)
0.002 0.998 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.002 0.998 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.002 0.998 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.002 0.998 0.000
M11 Other crystal arthropathies
0.002 0.998 0.000
Q37 Cleft palate with cleft lip
0.000 0.998 0.002
M05.28 Rheumatoid vasculitis (Other)
0.002 0.998 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.002 0.998 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.002 0.998 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.002 0.998 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.002 0.998 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.002 0.998 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.002 0.998 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.002 0.998 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.002 0.998 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.002 0.998 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.002 0.998 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.002 0.998 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.002 0.998 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.002 0.998 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.002 0.998 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.002 0.998 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.002 0.998 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.000 0.998 0.002
Q99 Other chromosome abnormalities, not elsewhere classified
0.000 0.998 0.002
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.000 0.998 0.002
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.000 0.998 0.002
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.000 0.998 0.002
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.000 0.998 0.002
Q91 Edwards' syndrome and Patau's syndrome
0.000 0.998 0.002
Q14 Congenital malformations of posterior segment of eye
0.000 0.998 0.002
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.002 0.998 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.002 0.998 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.002 0.998 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.002 0.998 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.002 0.998 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.002 0.998 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.002 0.998 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.002 0.998 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.002 0.998 0.000
R22.1 Localised swelling, mass and lump, neck
0.000 0.998 0.002
M05.19 Rheumatoid lung disease (Site unspecified)
0.002 0.998 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.002 0.998 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.002 0.998 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.002 0.998 0.000
M09.0 Juvenile arthritis in psoriasis
0.002 0.998 0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance
0.000 0.998 0.002
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.002 0.998 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.000 0.998 0.002
Q55 Other congenital malformations of male genital organs
0.000 0.998 0.002
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.000 0.998 0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.000 0.998 0.002
N05.7 Diffuse crescentic glomerulonephritis
0.002 0.998 0.000
N05 Unspecified nephritic syndrome
0.002 0.998 0.000
Q12 Congenital lens malformations
0.000 0.998 0.002
Q51 Congenital malformations of uterus and cervix
0.000 0.998 0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.002 0.998 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.002 0.998 0.000
M05.18 Rheumatoid lung disease (Other)
0.002 0.998 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.002 0.998 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.002 0.998 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.002 0.998 0.000
M05.14 Rheumatoid lung disease (Hand)
0.002 0.998 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.002 0.998 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.002 0.998 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.002 0.998 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.002 0.998 0.000
C71.3 Parietal lobe
0.000 0.998 0.002
N04.9 Unspecified
0.002 0.998 0.000
T91.3 Sequelae of injury of spinal cord
0.000 0.998 0.002
Q83 Congenital malformations of breast
0.000 0.998 0.002
M12.24 Villonodular synovitis (pigmented) (Hand)
0.002 0.998 0.000
K74.6 Other and unspecified cirrhosis of liver
0.002 0.998 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.000 0.998 0.002
Q90 Down's syndrome
0.000 0.998 0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.002 0.998 0.000
Q18.9 Congenital malformation of face and neck, unspecified
0.000 0.998 0.002
Q18.8 Other specified congenital malformations of face and neck
0.000 0.998 0.002
Q18.7 Microcheilia
0.000 0.998 0.002
Q18.6 Macrocheilia
0.000 0.998 0.002
Q18.5 Microstomia
0.000 0.998 0.002
Q18.4 Macrostomia
0.000 0.998 0.002
Q18.3 Webbing of neck
0.000 0.998 0.002
Q18.2 Other branchial cleft malformations
0.000 0.998 0.002
Q18.1 Preauricular sinus and cyst
0.000 0.998 0.002
Q30.9 Congenital malformation of nose, unspecified
0.000 0.998 0.002
Q30.8 Other congenital malformations of nose
0.000 0.998 0.002
Q30.3 Congenital perforated nasal septum
0.000 0.998 0.002
Q30.2 Fissured, notched and cleft nose
0.000 0.998 0.002
Q30.1 Agenesis and underdevelopment of nose
0.000 0.998 0.002
Q30.0 Choanal atresia
0.000 0.998 0.002
Q31.9 Congenital malformation of larynx, unspecified
0.000 0.998 0.002
Q31.8 Other congenital malformations of larynx
0.000 0.998 0.002
Q31.5 Congenital laryngomalacia
0.000 0.998 0.002
Q31.4 Congenital laryngeal stridor
0.000 0.998 0.002
Q31.3 Laryngocele
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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